Hub : Genes

GLDC

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2390	0.0520	8.2e-10	0.103	0.106	0.140	0.127	0.150	1.9e-12	7.7e-13	1.2e-16	3.3e-15	8.5e-18
2	ROSMAP	Brain Pre-frontal Cortex	0.1081	0.0414	1.7e-03	-0.002	0.006	0.013	0.008	-0.002	1.0e+00	4.3e-02	7.4e-03	2.5e-02	6.0e-01
3	TCGA	Breast Invasive Carcinoma	0.0652	0.0227	2.7e-07	0.024	0.039	0.044	NA	0.047	7.1e-06	1.8e-08	2.0e-09	NA	5.8e-10
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.1320	0.0369	1.2e-09	0.091	0.080	0.087	NA	0.092	1.8e-10	2.8e-09	5.3e-10	NA	1.7e-10
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1600	0.0640	2.7e-04	0.116	0.028	0.082	NA	0.086	3.6e-07	1.0e-02	2.0e-05	NA	1.2e-05
6	TCGA	Lung Adenocarcinoma	0.0466	0.0194	8.1e-04	0.012	0.028	0.024	NA	0.028	1.3e-02	2.6e-04	6.8e-04	NA	2.6e-04
7	TCGA	Prostate Adenocarcinoma	0.3276	0.0510	0.0e+00	0.333	0.301	0.325	NA	0.335	8.8e-36	7.1e-32	9.7e-35	NA	4.8e-36
8	TCGA	Thyroid Carcinoma	0.1110	0.0390	1.5e-05	0.103	0.060	0.080	NA	0.093	3.2e-10	1.6e-06	3.1e-08	NA	2.2e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.3	0.5	1.4	0.7	0.6	-0.3	0.5	0.4	-1.2	-0.7	-1.0
Bipolar Disorder or Schizophrenia	0.3	0.7	2.2	0.9	0.2	0.2	1.4	0.4	-1.5	0.5	-0.0
Depressed Affect (Nagel 2018)	1.0	2.1	4.0	-0.9	-0.2	1.2	-2.0	-1.4	1.4	1.6	-1.9
Depression (Nagel 2018)	2.4	3.7	9.3	-1.0	0.6	2.6	-3.0	-0.7	3.0	1.4	-0.8
Intelligence (Savage-Jansen 2018)	0.3	1.0	4.2	-0.7	-0.4	-1.0	0.1	-0.9	-2.0	-1.0	-0.4
Neuroticism (Nagel 2018)	1.2	2.9	7.5	-1.9	-0.6	1.9	-2.7	-1.2	1.9	1.1	-1.3
Schizophrenia (2018)	0.3	0.7	1.8	0.6	-0.2	0.5	1.4	0.3	-0.9	1.2	0.8
Schizophrenia vs Biploar Disorder	0.7	1.0	3.3	0.7	0.4	1.3	-0.2	0.5	0.9	1.0	1.8
Worry (Nagel 2018)	0.4	0.9	1.7	-1.3	-0.8	1.3	-1.0	0.9	1.3	-0.0	0.0
Alzheimer’s Disease (in mother)	2.6	3.0	8.5	2.9	2.8	-1.6	1.1	0.3	-1.4	-1.5	-0.3
Alzheimer’s Disease (in father)	0.6	0.6	1.8	-0.4	-1.1	-1.1	-0.2	-1.3	-0.9	-0.1	-0.0
Alzheimer’s Disease (including proxy)	1.0	1.4	5.2	2.3	2.2	-0.3	0.1	-0.3	-0.4	-0.8	0.2
Crohns Disease (2017)	0.3	0.7	1.5	-1.2	0.6	-0.6	0.9	0.3	-1.1	-0.7	-0.8
Irritable Bowel Disease (IBD)	0.7	1.6	5.4	-0.3	0.1	-1.4	2.0	0.2	-2.3	-0.0	-1.2
Ulcerative Colitis (UC)	1.0	1.9	6.3	0.7	-0.6	-1.4	2.3	0.1	-2.5	0.5	-0.8
Major Depression (MDD)	0.5	0.6	1.4	0.7	0.4	0.2	1.1	-0.2	-0.6	1.2	0.9
Reaction Time	0.5	1.0	4.2	2.0	1.2	0.7	0.8	1.1	0.3	-0.1	0.4
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.5	0.4	-0.7	0.6	-0.1	-0.1	-0.7	-0.1	-0.1
Breast Cancer	0.4	0.9	4.0	1.0	0.3	0.4	-0.5	-0.1	2.0	1.2	0.4
Ovarian Cancer	0.7	0.9	3.2	-0.2	0.5	-0.7	1.8	-0.5	-1.3	0.9	0.3
Prostate Cancer	0.9	1.2	4.7	-0.7	-1.0	-0.6	0.6	2.2	0.3	-0.6	1.6
Age at First Birth	0.5	0.7	3.2	0.6	-0.7	0.6	0.3	0.4	0.1	1.0	1.8
Bipolar Disorder (2011)	0.9	0.8	2.3	-1.2	-0.7	0.3	0.5	-0.7	-1.5	0.4	-1.3
Body Mass Index (BMI) (2010)	0.3	0.4	2.3	-1.5	-0.4	0.6	-0.4	0.5	0.1	-0.5	0.2
Coronary Artery Disease (CAD)	0.9	1.1	2.8	-1.7	-1.6	-0.1	1.2	0.8	-0.9	-0.1	-0.6
Crohns Disease (2012)	0.8	1.4	4.0	-1.1	-0.5	-1.2	1.0	0.8	-1.5	-2.0	-0.1
Mean Putamen Volume	1.7	1.9	4.1	-0.6	-0.6	2.0	-2.0	-0.3	1.7	1.6	1.1
Fasting Glucose	1.0	1.2	3.2	-1.3	0.1	-0.7	1.2	-1.8	-1.4	-0.5	0.7
HbA1C	0.2	0.3	0.7	-0.2	-0.4	0.7	-0.1	-0.8	-0.3	0.6	-0.4
HDL Cholesterol	0.3	0.5	1.2	-0.1	-0.6	-1.1	0.5	-1.0	-0.9	-0.5	0.7
LDL Cholesterol	0.4	0.6	2.6	0.8	-0.9	0.1	0.4	1.6	0.1	0.7	-0.3
Lupus	0.8	1.2	2.4	1.2	-1.1	-0.3	1.6	-1.2	-1.4	-0.1	0.9
Neuroticism (2016)	1.3	1.8	6.3	-2.5	-1.8	0.6	-0.6	-1.7	0.1	1.1	-0.6
Primary Biliary Cirrhosis	0.6	0.8	3.1	-0.3	0.6	-0.9	1.8	0.4	-1.0	-1.0	0.4
Rheumatoid Arthritis	2.3	3.2	5.2	-1.9	-1.0	2.3	-2.0	-2.0	1.9	1.1	-1.7
Schizophrenia (2014)	0.4	0.8	2.3	0.9	0.8	0.5	1.5	0.2	-1.2	0.8	0.7
Triglycerides	0.7	1.1	4.4	-0.2	-0.9	-0.6	1.7	2.1	-0.2	-0.4	0.0
Type 2 Diabetes (T2D) (2012)	1.2	1.3	5.7	-0.9	-2.4	0.3	-0.4	0.3	0.6	-0.3	1.8
Ulcerative Colitis	2.4	3.4	10.2	-0.7	-1.6	-1.7	3.2	0.8	-3.2	-0.1	-0.8
Blood Eosinophil Count	15.0	115.3	718.2	10.6	26.8	-2.1	-3.2	-1.0	0.9	-2.7	-8.3
Blood Platelet Count	0.1	1.4	3.7	-1.0	-0.9	-1.3	1.0	0.8	-1.9	-1.4	-0.1
Blood Red Count	0.2	2.2	7.1	1.1	0.8	-2.7	2.5	0.4	-1.3	-0.7	0.1
Blood White Count	0.3	1.9	5.7	0.5	2.4	-1.6	1.1	-1.0	-1.7	0.7	-1.0
Heel T-Score	0.4	3.4	13.7	-1.7	-3.7	1.2	-0.7	0.8	1.2	0.4	2.5
BMI	0.2	1.3	2.7	-1.3	-1.6	0.6	-1.3	-1.6	1.3	0.4	-0.1
Height	0.6	11.2	31.8	3.8	2.4	-3.5	5.6	3.6	-3.1	-1.7	-0.2
Waist Hip Ratio (WHR)	0.2	1.1	4.4	-1.0	-0.3	1.3	0.2	0.2	0.0	2.1	1.2
Systolic Blood Pressure	0.1	0.4	1.0	-0.5	-1.0	0.2	-0.8	-0.9	-0.3	-0.6	-0.2
Smoking Status	0.5	1.2	3.4	-1.2	-1.8	-0.5	0.7	1.5	-0.1	-0.9	1.1
Allergy or Eczema	3.9	10.4	57.1	4.3	7.6	1.1	-1.1	0.3	1.3	1.2	-1.3
Cardiovascular Disease	0.3	0.9	1.7	-1.3	-1.3	0.3	-0.7	-1.0	-0.5	-0.3	-1.2
Hypothyroidism (self reported)	0.7	1.6	7.1	-2.7	-0.5	-0.0	0.8	-1.0	-1.2	-1.3	0.6
Respiratory disease	10.4	23.2	117.1	7.3	10.8	1.1	-1.5	1.7	1.4	0.1	-2.7
Type 2 Diabetes (T2D) (2018)	0.2	0.3	2.1	-0.2	-1.4	-0.1	-0.2	0.1	-0.4	-0.0	-0.5
Lung FEV1/FVC ratio	1.1	5.8	21.7	-3.4	-4.7	-2.0	2.1	-1.0	-1.2	-0.4	1.4
Lung FVC	0.9	4.4	11.5	-1.6	-0.3	2.3	-2.7	-3.4	0.4	1.0	2.7
Neuroticism	1.0	2.3	3.8	-1.6	-0.7	1.8	-2.0	-0.2	1.5	1.8	-1.6
Chronotype (morning person)	0.5	1.1	2.9	0.6	0.6	-1.3	1.7	-0.3	-1.1	-0.4	-1.4
Hair Pigment	0.1	3.6	7.1	-0.6	1.7	-2.5	2.3	1.0	-1.9	-2.7	-1.4
Tanning	0.0	0.5	2.5	0.4	1.6	0.1	-0.7	0.0	0.4	0.6	-0.0
Hand grip strength (left)	0.5	1.3	6.5	0.4	0.5	-0.9	1.0	0.4	-0.7	-1.1	2.5
Number of treatments/medications taken	0.4	0.8	4.2	-0.5	2.0	0.2	-0.2	0.2	0.3	-1.1	-0.4
Average weekly spirits intake	0.6	0.7	2.5	0.6	0.5	-0.1	-1.3	0.0	0.7	-0.5	-1.6
Sensitivity / hurt feelings	0.6	1.0	4.8	-1.4	-0.6	-0.2	-0.4	0.8	0.2	-0.1	-2.2
Frequency of depressed mood in last 2 weeks	1.8	2.5	7.2	-0.9	-1.0	1.8	-2.7	-0.3	2.5	0.9	-0.5
Hearing difficulty/problems: Yes	0.4	0.5	1.6	0.6	0.6	-0.4	1.3	-0.5	-0.6	1.1	-0.2
Relative age of first facial hair	1.2	2.5	8.2	-1.6	-0.0	-1.6	1.9	-1.0	-2.9	-1.2	-0.2
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	4.1	-0.5	-0.8	-1.4	1.7	0.2	-2.0	-1.7	-1.6
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.6	0.7	-0.3	0.6	0.5	1.3	0.6	-0.1	0.7
Ever had hysterectomy (womb removed)	2.0	2.2	7.4	-1.8	-0.3	1.1	-2.7	-1.1	2.0	0.6	0.3
Systolic blood pressure, automated reading	0.3	0.8	4.2	-1.3	-2.0	-0.2	-0.2	-0.1	-0.7	-0.4	-0.2
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.6	-1.6	-1.4	-0.1	-1.1	-1.4	0.9	0.2	-0.3
Angina	2.0	2.7	8.0	-2.8	-2.7	-0.5	0.0	-0.9	-1.4	-1.4	-0.9
Medication for hormone replacement therapy	0.8	0.9	2.5	-0.8	-1.3	-0.4	0.4	-1.2	-0.9	0.4	1.6
Vitamin and mineral supplements	1.1	1.5	3.6	1.0	-0.2	-1.9	1.8	0.4	-1.8	-0.9	0.3
Supplements: Zinc	1.1	1.2	3.2	-0.5	0.6	0.8	-1.8	-0.1	1.8	0.5	-1.4
Medication: Co-codamol	0.3	0.3	1.2	0.0	-0.7	0.4	-0.4	0.6	1.1	-0.1	-0.2
Medication: Metformin	2.0	2.8	6.4	-2.4	-1.6	-1.1	-0.0	-2.5	-1.9	-0.6	-1.5
Diabetes (father)	0.4	0.5	2.1	-0.5	0.1	-0.9	0.1	-1.4	-0.7	0.0	0.2
Diabetes (mother)	0.7	0.8	2.1	0.8	0.1	0.2	-1.3	-0.2	1.4	0.7	-1.3
Severe depression (siblings)	0.5	0.6	1.7	-0.7	-0.3	0.3	-1.3	-0.6	0.7	-0.8	-0.8
Pack years adult smoking proportion	0.4	0.6	1.8	-0.7	1.3	-0.4	0.2	0.5	-0.4	0.5	-1.4
Impedance of leg (right)	0.2	1.2	3.5	1.9	0.4	-0.2	1.3	0.1	-1.1	1.6	-0.3
Leg fat-free mass (left)	0.1	0.7	2.2	0.0	0.5	-1.1	1.1	-0.3	-0.3	-1.5	0.7
Trunk fat percentage	0.2	0.7	2.8	-0.8	0.1	-0.7	-0.2	-1.1	-0.1	0.3	-1.7
Hand grip strength (right)	1.0	2.8	14.2	1.5	0.8	-1.0	1.3	1.2	0.2	-1.1	3.8
Townsend deprivation index at recruitment	0.8	1.1	4.2	1.9	0.6	0.4	-0.0	2.0	-0.1	-0.6	-0.2
Current tobacco smoking	0.3	0.6	1.7	0.1	-0.7	-0.9	0.1	1.3	0.2	-0.7	0.9
Average weekly fortified wine intake	1.1	1.3	3.2	1.2	0.8	1.1	-1.5	0.7	1.8	0.2	1.0
Maternal smoking around birth	0.4	0.6	1.4	0.9	0.8	0.1	-0.1	0.9	-0.5	-1.0	1.2
Fed-up feelings	0.5	1.0	2.2	-1.2	0.6	0.5	-1.3	-0.5	0.7	1.1	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	2.3	3.0	9.8	-1.4	-0.6	2.2	-3.1	-0.1	2.4	1.2	-0.3
Relative age voice broke	1.7	2.6	6.9	-1.0	1.0	-2.2	1.4	-0.4	-2.6	-2.2	-0.5
Taking other prescription medications	1.2	1.8	7.0	1.7	2.6	1.2	0.6	1.6	0.5	0.4	-0.2
Age when periods started (menarche)	0.5	1.2	2.7	-0.4	1.6	-1.1	1.3	0.1	-1.6	-1.0	-0.0
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.1	-0.7	0.2	0.1	0.4	0.5	0.3	0.5	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	3.4	0.3	-1.3	0.7	-0.2	0.3	0.9	0.6	1.9
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	2.1	-0.1	0.4	0.1	0.6	-1.4	-0.1	0.8	-0.2
Qualifications: CSEs or equivalent	1.6	2.1	5.6	-1.6	0.7	0.2	-2.1	-2.4	1.6	1.1	-0.2
Serious illness, injury or assault to yourself	0.4	0.4	0.8	-0.4	0.9	0.2	0.4	0.9	0.3	0.9	0.8
High blood pressure	0.6	1.7	4.8	-2.2	-1.2	-0.6	-0.6	-1.6	-1.1	-1.0	-1.3
Hayfever, allergic rhinitis or eczema	2.9	6.4	34.5	3.8	5.9	-0.0	0.2	-0.1	-0.0	0.9	-1.0
Multivitamins +/- minerals	0.4	0.5	1.0	0.1	0.8	0.9	-1.0	-0.3	0.9	0.4	0.3
Stomach or abdominal pain in last month	0.6	0.8	2.3	-1.5	-1.0	0.6	-0.5	-0.5	0.1	-1.2	0.8
Supplements: Glucosamine	2.0	2.6	14.1	1.8	3.8	0.4	-0.1	-1.0	0.8	1.2	-0.4
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	2.9	-0.8	-1.7	0.0	-0.9	1.1	0.6	-0.5	-1.2
Medication: Atenolol	2.6	3.3	8.7	-2.8	-3.0	-0.7	-0.7	-1.9	-0.7	-1.2	-1.9
Medication: Levothyroxine sodium	1.3	2.2	13.2	-3.6	-0.9	0.4	0.0	-0.9	-0.9	-1.3	-0.7
Sitting height	0.0	0.2	0.8	0.9	0.3	-0.4	0.9	-0.1	0.0	0.3	0.1
Chronic bronchitis/emphysema (father)	1.9	2.3	4.4	1.3	0.9	-1.9	2.1	1.1	-2.0	-0.7	-1.5
High blood pressure (mother)	0.9	1.3	3.5	-0.8	0.5	-1.5	1.9	0.5	-1.3	-0.2	-1.2
Body mass index (BMI)	0.3	1.3	4.3	-2.1	-1.3	-0.1	-1.2	-1.3	0.9	-0.5	0.2
Impedance of leg (left)	0.3	1.6	4.0	2.0	0.2	-0.6	1.8	0.7	-1.4	1.5	-0.1
Leg predicted mass (left)	0.1	0.7	2.3	0.1	0.6	-1.2	1.1	-0.3	-0.4	-1.5	0.6
Trunk fat mass	0.1	0.4	1.0	-0.6	0.2	-0.9	0.2	-1.0	-0.3	-0.0	-1.0
Waist circumference	0.2	0.6	2.8	-1.7	-0.1	-0.4	-0.7	-1.1	0.0	-0.3	-0.6
Number of incorrect matches in round	0.4	0.6	1.2	-0.4	-0.3	0.6	0.9	1.1	0.0	1.0	1.1
Past tobacco smoking	2.3	4.2	16.2	1.7	4.0	-0.6	-2.0	-2.8	0.7	0.6	-1.0
Alcohol usually taken with meals	1.2	1.9	5.3	-0.6	-0.1	1.4	-1.9	-0.5	1.9	-0.7	2.3
Nervous feelings	0.4	0.8	2.9	0.2	-0.7	0.7	-1.0	1.7	1.0	-0.7	-0.3
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	4.1	-1.1	-1.7	1.7	-2.0	-0.0	1.6	1.2	-0.3
Hearing difficulty/problems with background noise	1.2	1.9	4.6	1.7	0.7	1.2	0.1	1.7	1.9	2.1	0.0
Hair/balding pattern: Pattern 2	1.1	1.5	4.2	1.9	2.0	-0.1	-0.8	0.4	1.5	0.0	-1.0
Had menopause	0.5	0.6	1.6	1.0	0.4	-0.2	0.1	1.3	0.5	0.8	-1.2
Had other major operations	0.2	0.2	0.6	-0.8	-0.7	-0.0	-0.1	0.1	-0.3	-0.5	-0.4
Forced vital capacity (FVC)	0.4	1.5	3.6	0.9	1.2	-0.9	1.1	-0.5	-1.9	-0.7	1.9
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.8	0.3	-0.6	0.1	0.4	0.9	0.0	-0.2	0.5
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.5	-0.5	-1.2	1.1	-1.0	-0.9	0.9	0.1	0.3
Qualifications: None of the above	0.2	0.5	2.1	0.2	1.0	-0.4	0.7	1.4	0.1	0.0	-0.5
Financial difficulties in last 2 years	0.4	0.5	1.5	-0.9	-0.0	-0.4	0.7	0.8	-0.4	-0.3	1.2
Mouth/teeth dental problems	0.2	0.3	0.9	-0.5	-0.7	-0.1	0.2	-1.0	-0.2	0.1	0.7
Heart attack	0.6	0.7	1.8	-1.3	-1.3	0.5	-0.6	-0.8	-0.1	-0.8	-0.3
Allergy	6.0	13.8	78.6	-5.3	-8.9	-0.2	1.0	0.0	-0.5	-0.3	1.6
Pain all over the body in last month	1.0	1.0	5.9	-0.5	-0.6	-0.9	-0.6	-0.1	-0.3	-2.4	0.7
Diabetes (self-reported)	0.8	1.2	3.0	-1.7	-1.0	-1.2	-0.2	-0.9	-0.9	-0.9	-1.3
Hayfever/allergic rhinitis (self-reported)	5.6	7.4	31.5	4.6	5.6	0.4	-0.2	1.3	1.0	1.3	-1.4
Medication: Ramipril	1.5	1.9	5.4	-0.9	-0.1	-1.6	1.4	-1.7	-2.3	-1.0	-0.9
Medication: Simvastatin	0.6	0.8	2.4	-1.5	-0.9	-0.2	0.9	-0.6	-1.2	-0.5	-0.8
Fluid intelligence score	0.3	0.5	1.9	1.4	0.8	0.4	0.8	0.4	-0.3	0.5	0.8
Illnesses of siblings	1.8	2.5	12.2	1.7	0.4	-0.3	1.7	0.9	-0.9	0.4	3.5
Neuroticism score	0.6	1.3	2.3	-1.4	-0.9	1.2	-1.3	0.8	1.5	0.5	-0.8
Weight	0.1	0.4	1.5	-0.5	0.3	-1.2	0.4	-0.7	-0.2	-1.0	-0.0
Impedance of arm (right)	0.3	1.5	5.1	1.4	1.6	-0.1	1.0	0.5	-1.0	0.8	-2.3
Arm fat percentage (right)	0.3	1.1	4.0	-2.0	-0.2	-0.4	-1.0	-1.6	0.3	-0.0	-1.1
Trunk fat-free mass	0.2	1.1	1.6	1.1	1.1	-1.2	1.3	-0.1	-0.5	-1.3	1.3
Hip circumference	0.2	0.7	1.9	-0.7	0.1	-0.8	-0.8	-0.7	0.2	-1.4	-1.2
Time employed in main current job	0.7	0.8	3.5	0.9	1.2	0.2	-0.3	0.2	0.5	1.9	-0.0
Alcohol intake versus 10 years previously	1.1	1.6	3.7	1.3	-0.6	0.1	1.2	1.9	0.2	1.5	1.8
Father’s age at death	0.3	0.4	1.4	0.2	0.1	-0.1	-1.2	-0.2	1.1	0.5	0.3
Worrier / anxious feelings	1.0	1.9	5.2	-1.7	-2.3	1.4	-1.8	0.4	1.4	-0.1	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.4	-0.6	0.1	-0.3	-1.1	-0.2	1.2	0.3	-0.5
Falls in the last year	0.5	0.7	3.3	-1.8	-0.9	0.2	-0.5	-0.1	-0.6	-0.4	-0.8
Hair/balding pattern: Pattern 3	1.3	1.9	3.4	-0.9	-1.6	1.2	1.8	1.2	0.5	1.9	1.4
Number of live births	1.6	2.3	7.5	2.2	1.1	-1.5	0.0	1.3	0.2	-0.8	-2.7
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	6.3	0.0	-0.4	-0.7	1.5	-1.0	-1.8	-0.3	2.5
Pulse rate	0.5	0.9	2.5	-0.6	0.9	-1.0	0.8	-0.1	-1.3	-1.6	0.6
Happiness	1.9	2.3	4.4	-0.7	-0.8	1.6	-2.1	-1.4	1.2	2.0	1.8
Noisy workplace	0.2	0.3	0.7	-0.3	-0.4	-0.1	-0.7	0.3	0.8	-0.6	0.8
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.9	0.9	-0.4	-0.3	0.5	0.5	-0.4	0.3	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	2.8	1.0	0.9	-0.6	1.2	-0.6	-1.7	-0.7	0.7
Mouth/teeth dental problems: Dentures	0.2	0.4	1.0	-1.0	0.5	-0.6	0.7	0.2	-0.8	-0.5	-0.3
Asthma	11.1	21.9	122.0	6.4	11.0	0.7	-2.2	0.8	1.4	-0.6	-1.8
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.0	-1.4	-1.1	-1.0	1.1	0.3	-0.6	-0.3	1.1
Medication: Cholesterol lowering	0.6	1.0	2.1	-1.3	-0.2	0.1	-0.2	-1.1	-0.7	1.4	-1.5
Depression (self-reported)	1.4	1.7	6.7	-2.6	-1.0	0.6	-1.6	-1.1	0.6	-0.3	-0.8
Medication: Lansoprazole	0.2	0.3	0.7	0.7	-0.0	-0.1	0.4	0.8	0.1	-0.7	-0.6
Prospective memory result	0.6	0.7	1.9	-1.0	0.9	-1.4	1.0	0.7	0.0	-0.1	0.7
Lung cancer (father)	0.3	0.3	1.1	0.5	0.0	-0.1	0.0	1.0	0.5	0.1	-1.0
Illnesses of mother	0.6	0.7	2.4	0.1	-1.0	1.1	-0.1	0.4	0.9	0.6	1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.1	6.5	-0.4	-0.5	-0.7	1.4	-1.8	-2.0	-0.2	2.6
Pulse wave Arterial Stiffness index	1.9	2.2	12.2	3.5	1.9	0.2	0.6	0.9	0.7	-0.4	0.6
Impedance of arm (left)	0.5	2.2	7.8	1.6	2.1	0.2	0.6	0.2	-0.8	1.3	-2.8
Arm fat mass (right)	0.1	0.5	1.5	-1.2	0.1	-0.6	-0.6	-1.2	0.3	-0.3	-0.6
Trunk predicted mass	0.2	1.1	1.8	1.1	1.2	-1.2	1.2	-0.1	-0.5	-1.2	1.3
Standing height	0.5	5.3	10.6	3.2	3.0	-2.4	3.2	1.0	-2.1	-0.8	-0.8
Length of working week for main job	0.3	0.3	0.8	-0.5	-0.4	-0.5	0.9	0.3	-0.9	-0.5	-0.4
Exposure to tobacco smoke at home	1.2	1.4	3.4	1.7	0.7	1.2	-0.0	1.8	1.0	0.7	1.2
Breastfed as a baby	0.4	0.5	1.2	0.6	-0.1	1.1	-0.5	0.9	0.9	0.7	-0.1
Tense / ‘highly strung’	1.1	1.8	5.7	-0.6	0.3	1.4	-2.2	0.7	2.4	0.7	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.9	-0.8	-0.2	1.4	-1.4	-1.0	0.2	-0.2	-0.7
Hair/balding pattern: Pattern 4	0.7	1.7	3.9	0.0	-1.2	-1.2	-1.4	-1.1	-1.4	-2.0	-1.2
Birth weight of first child	0.6	1.1	3.7	0.5	-0.6	1.5	-0.2	1.0	1.0	0.2	1.9
Peak expiratory flow (PEF)	0.4	0.9	2.4	0.1	0.1	-1.3	1.2	-0.7	-1.6	-0.8	0.8
Pulse wave reflection index	1.0	1.2	2.9	1.4	-0.2	1.7	0.5	1.1	1.2	0.9	1.1
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.3	-0.1	-0.5	1.6	-1.8	-0.2	1.8	0.3	-0.1
Loud music exposure frequency	0.6	0.7	2.4	-0.3	-0.4	-0.3	1.5	1.1	-0.9	-0.9	0.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.8	0.9	-0.3	0.5	-0.4	0.4	0.5	-0.2	0.9
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	2.7	1.0	-0.7	-0.7	0.5	1.4	0.1	-1.0	1.6
Blood clot in the leg (DVT)	0.5	0.7	1.7	1.2	1.3	0.4	-0.7	-0.7	0.8	0.7	-0.2
Medication: Paracetamol	0.4	0.7	2.2	-1.2	-0.1	-0.1	0.1	0.2	-0.1	-1.5	1.3
Headache pain in last month	0.5	0.9	3.9	0.9	1.0	-1.1	-0.2	0.3	-0.1	-2.0	-0.7
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.7	1.1	-0.0	0.2	-0.3	0.8	0.6	-0.9	1.3
Glaucoma (self-reported)	0.6	0.8	1.7	0.8	1.0	-1.0	1.3	0.2	-1.2	0.5	0.5
Gout (self-reported)	0.5	0.7	2.5	0.4	-1.6	-0.8	0.4	0.9	-0.6	-0.7	0.1
Hypothyroidism/myxoedema (self-reported)	1.1	2.1	9.4	-3.1	-0.3	0.2	1.0	-0.9	-1.5	-1.8	0.1
Medication: Amlodipine	0.2	0.2	1.1	0.8	-0.0	-0.2	0.1	-0.1	0.2	0.4	-1.1
Medication: Ventolin 100micrograms inhaler	6.4	8.2	40.3	4.0	6.3	-0.9	-0.1	1.3	-1.0	-1.8	-1.7
Birth weight	0.7	1.4	3.8	-0.4	-0.7	1.7	-0.8	1.4	2.0	1.4	0.3
Chronic bronchitis/emphysema (mother)	1.1	1.3	4.8	-1.2	-1.0	0.8	-1.1	-0.9	0.6	-0.6	2.2
High blood pressure (siblings)	0.9	1.3	7.5	-0.9	0.4	0.3	-0.7	-0.9	0.3	0.0	-2.7
Forced vital capacity (FVC), Best measure	0.5	1.7	4.7	0.7	1.5	-0.5	1.0	-1.3	-1.8	-0.4	2.2
Body fat percentage	0.2	0.6	1.8	-1.2	-0.2	-0.6	-0.2	-1.3	-0.1	0.4	-1.0
Leg fat percentage (right)	0.2	0.8	2.1	-1.4	-1.4	-0.3	0.0	-1.4	-0.2	0.4	0.4
Arm fat-free mass (right)	0.2	0.8	1.8	0.8	0.5	-1.2	1.1	-0.3	-0.4	-1.0	1.3
Exposure to tobacco smoke outside home	0.5	0.7	1.4	0.8	0.9	-0.6	-0.7	1.1	0.8	-1.2	0.4
Comparative body size at age 10	0.3	0.7	2.6	-0.9	0.3	0.5	-0.8	-1.0	1.6	-0.5	-0.2
Number of full brothers	0.6	0.7	3.9	1.0	0.3	-0.6	0.2	2.0	0.5	-0.5	-0.3
Worry too long after embarrassment	0.4	0.8	2.2	-0.4	-0.5	1.3	-0.9	0.7	1.5	0.6	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	3.2	0.4	-0.7	1.3	-1.8	-0.6	0.4	-1.2	-0.2
Wheeze or whistling in the chest in last year	4.8	8.6	44.4	2.8	6.7	-0.6	-1.6	1.6	0.5	-1.3	-3.0
Number of children fathered	0.9	1.0	2.3	-1.1	-0.1	-0.4	-1.3	-0.8	0.6	-1.5	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.6	3.3	-1.8	-0.9	-0.9	1.2	-1.4	-1.8	-0.7	-0.9
Age at first live birth	0.3	0.5	1.3	0.6	0.8	0.3	-0.4	0.6	-0.4	-1.2	1.1
Pulse wave peak to peak time	1.7	2.0	10.8	-3.3	-1.6	-0.3	-0.4	-1.0	-0.8	0.5	-0.6
Health satisfaction	1.3	1.7	6.0	-0.9	-1.1	0.7	-0.9	-2.4	0.1	2.0	-0.6
Shortness of breath walking on level ground	1.2	1.5	4.1	0.5	1.2	0.2	-2.0	-0.4	1.3	-0.1	-2.0
Qualifications: College or University degree	0.2	0.6	2.6	1.6	0.7	-0.7	0.6	0.1	-0.5	0.4	0.4
Eye problems/disorders: None of the above	0.4	0.5	1.6	-0.5	0.7	0.4	-0.4	-0.6	0.3	0.7	-1.3
Mouth/teeth dental problems: Loose teeth	2.5	3.0	7.1	-2.3	-2.7	1.4	-1.2	0.9	1.1	1.2	2.2
Emphysema/chronic bronchitis	0.6	0.6	1.9	-0.9	-0.1	-0.4	-0.4	-1.3	-0.3	-0.4	-1.4
Medication for pain relief, constipation, heartburn	0.6	1.0	2.5	1.6	1.1	-0.1	-0.2	-0.9	-0.4	1.3	-1.1
Neck or shoulder pain in last month	0.3	0.4	1.1	-0.2	0.8	-0.4	0.8	1.0	0.3	0.6	-0.7
Medication: Blood pressure	0.5	0.9	3.2	-1.1	0.3	-0.7	0.1	-1.8	-0.6	0.2	-1.3
Angina (self-reported)	1.8	2.3	6.9	-2.6	-2.6	-0.4	-0.2	-1.1	-1.3	-1.3	-0.7
Migraine (self-reported)	0.4	0.5	3.1	0.1	-1.8	0.4	-0.3	0.7	0.1	-0.2	0.1
Medication: Ibuprofen	0.9	1.1	3.4	-1.8	-0.9	-0.9	0.9	-0.0	-0.5	-0.3	1.6
Medication: Allopurinol	0.8	1.1	2.5	0.8	-1.2	-1.0	0.1	1.6	-0.4	-1.6	-0.5
Medication: Omeprazole	0.7	0.8	3.4	-0.2	-1.8	0.6	0.3	1.5	0.5	-0.2	0.2
Medication: Seretide 50 evohaler	1.8	2.1	10.5	0.8	3.2	0.4	-1.2	-0.1	0.5	0.1	-2.0
Mean time to correctly identify matches	0.6	1.1	3.6	1.9	1.3	0.1	0.9	1.0	-0.1	-0.2	-1.3
Heart disease (mother)	0.7	0.9	3.7	-1.9	-1.2	0.4	-1.1	-0.1	-0.1	-0.4	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.4	2.9	10.6	0.2	1.8	1.5	-3.2	-0.9	2.2	0.4	-1.0
Whole body fat mass	0.1	0.4	1.1	-0.9	0.1	-0.9	0.1	-1.1	-0.2	-0.1	-0.6
Leg fat mass (right)	0.1	0.3	1.0	-0.9	-0.4	-0.7	0.2	-1.0	-0.0	-0.3	0.4
Arm predicted mass (right)	0.2	1.1	2.7	0.8	0.5	-1.6	1.3	-0.1	-0.5	-1.1	1.3
Pulse rate, automated reading	0.4	1.2	3.2	0.6	0.9	-1.8	1.0	-0.0	-1.5	-1.3	0.2
Alcohol intake frequency.	0.3	0.7	2.3	-0.1	1.1	-0.3	1.5	0.6	-1.1	0.1	-0.0
Comparative height size at age 10	0.4	2.5	9.5	3.1	1.0	-1.1	1.7	2.1	-0.1	0.6	-0.9
Number of full sisters	0.8	1.0	3.5	-0.4	-1.2	-0.9	0.5	1.2	-0.0	-1.9	-0.1
Suffer from ‘nerves’	0.4	0.7	2.6	-1.0	0.3	1.6	-0.8	0.4	0.8	0.4	0.4
Overall health rating	0.3	0.7	2.3	-1.0	-0.1	-0.4	-0.8	-0.6	-0.1	-0.9	-1.5
Chest pain or discomfort	0.7	1.0	4.5	-0.2	-0.1	1.0	-2.1	0.2	1.6	-0.1	-0.1
Had major operations	1.2	1.4	4.8	-1.1	0.3	2.2	-0.4	-0.5	1.2	1.2	-1.4
Age at last live birth	1.1	1.6	4.8	2.2	1.9	-0.1	0.8	1.7	-0.7	-0.7	0.5
Family relationship satisfaction	0.4	0.5	1.3	0.4	1.1	0.7	-0.9	-0.7	-0.3	0.4	0.2
Leg pain on walking	1.0	1.2	5.3	0.4	0.6	1.2	-1.6	0.0	2.3	0.1	0.1
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	5.7	-1.0	-0.7	-0.7	-0.1	-0.8	-1.1	-2.4	0.4
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.7	-0.9	0.1	-0.4	0.7	-0.2	-0.3	0.5	-0.5
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	3.7	0.6	-1.9	-0.1	0.3	0.4	-0.8	-0.6	-1.5
Medication: Aspirin	0.7	1.0	2.8	-1.0	-1.6	1.7	-0.2	0.7	0.5	0.2	-0.5
Supplements: Vitamin C	1.4	1.7	4.1	-0.5	-1.2	1.9	-2.0	-0.5	1.7	0.9	0.1
Knee pain experienced in last month	1.0	1.6	5.3	-0.4	-0.8	1.3	-1.0	0.7	2.3	0.9	1.7
Hypertension (Self-reported)	0.7	1.8	5.9	-2.4	-1.4	-0.4	-0.7	-1.4	-1.0	-1.2	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	3.5	0.7	-0.2	1.4	-1.9	-0.2	1.5	-0.5	0.7
Illnesses of father: Heart disease	1.1	1.6	5.7	-0.8	-0.5	1.1	-1.2	-2.4	0.8	0.8	-1.4
Illnesses of siblings: Diabetes	1.8	2.2	6.1	-0.5	-1.0	0.5	-2.5	-1.6	1.4	-0.9	-2.1
Smoking status: Previous	2.2	3.3	10.9	-2.0	-3.3	0.2	2.3	1.9	-1.5	-0.4	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	3.0	0.2	1.7	-1.1	0.9	-1.0	-1.0	-0.2	-0.2
Whole body fat-free mass	0.2	1.1	1.9	0.9	1.0	-1.3	1.3	-0.0	-0.5	-1.4	1.1
Leg fat-free mass (right)	0.2	0.9	3.0	0.1	0.6	-1.3	1.2	0.2	-0.4	-1.7	0.7
Arm fat percentage (left)	0.3	1.1	2.9	-1.7	-0.0	-0.2	-1.0	-1.7	0.3	0.3	-1.2
Average weekly red wine intake	0.4	0.5	2.3	-0.8	0.4	0.7	-0.1	0.3	1.5	0.8	0.4
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.4	-0.5	1.1	-0.1	-0.9	-1.6	-0.5	-0.6	-0.7
Mood swings	0.5	0.9	2.9	-1.0	0.1	0.4	-1.4	-0.9	0.5	0.5	-1.7
Loneliness, isolation	0.7	1.0	2.4	1.0	1.0	-0.0	-1.2	1.6	1.0	-0.9	-0.3
Long-standing illness, disability or infirmity	1.1	1.7	6.2	-0.6	1.5	-0.5	0.1	-1.3	-1.3	-0.9	-2.5
Ever had bowel cancer screening	0.6	0.7	2.0	0.0	-1.0	0.5	-0.9	0.1	1.4	0.1	-1.2
Diabetes diagnosed by doctor	0.5	0.8	2.7	-1.6	-1.2	-0.1	-1.0	-0.7	0.2	0.1	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.7	-0.4	-0.4	-1.2	0.7	0.3	-1.3	0.0	-1.2
Friendships satisfaction	1.5	1.8	6.2	-0.8	0.3	0.6	-2.5	-1.3	1.9	0.8	1.2
Qualifications: nursing, teaching	0.4	0.6	2.0	0.7	0.6	-0.9	0.1	0.6	-0.7	0.1	-1.4
Commuting to job workplace: Walk	0.7	0.8	3.2	0.1	0.3	0.7	-0.8	-1.8	-0.5	0.5	-1.0
Eye problems/disorders: Cataract	1.4	1.7	4.5	2.1	0.9	-0.3	0.4	1.9	0.5	-1.2	1.6
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	4.6	0.4	0.2	1.8	-2.1	0.4	2.1	0.4	-0.2
Medication for cholesterol	0.5	0.7	2.3	1.5	1.1	-1.0	0.8	0.6	-0.2	-0.0	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	4.3	-1.3	-0.2	-1.5	-0.5	-1.9	-1.1	-2.1	0.9
Back pain experienced in last month	0.6	0.9	1.8	-0.9	0.5	1.1	-0.6	0.7	0.7	1.4	1.3
Mineral and other dietary supplements	1.5	2.0	3.7	-1.4	-1.4	-1.9	0.8	-1.0	-1.7	-1.8	0.9
Breast cancer (self-reported)	1.0	1.1	4.1	0.7	0.3	-1.5	2.0	1.2	-0.7	-0.4	0.2
Asthma (self-reported)	11.0	21.8	121.0	6.5	11.0	0.5	-2.0	1.0	1.4	-0.7	-1.8
Osteoporosis (self-reported)	0.6	0.7	2.4	1.6	-0.0	0.8	1.1	1.1	-0.2	-0.2	-0.6
Osteoarthritis (self-reported)	0.5	0.6	1.5	1.0	0.8	-0.3	-0.5	1.1	1.2	-0.2	0.2
Medication: Aspirin	1.1	1.4	5.6	-1.8	-2.4	1.3	-0.2	0.5	0.6	0.1	-0.2
Medication: Gliclazide	0.6	0.7	2.1	-1.4	-0.6	0.6	-0.8	-1.2	0.2	0.8	-0.5
Illnesses of father: None of the above (group 1)	0.7	0.8	2.9	0.4	0.4	-0.2	1.4	1.7	-0.7	-0.7	-0.4
Smoking status: Current	0.4	0.6	2.0	-0.0	-0.8	-0.8	-0.1	1.4	0.5	-0.7	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	5.9	-1.2	-1.7	0.7	-0.1	-1.9	-0.4	-0.1	2.4
Whole body water mass	0.2	1.0	1.8	0.7	0.9	-1.3	1.3	-0.1	-0.4	-1.3	1.1
Leg predicted mass (right)	0.2	0.9	2.9	0.1	0.5	-1.3	1.3	0.2	-0.5	-1.7	0.8
Arm fat mass (left)	0.1	0.5	1.5	-1.1	0.1	-0.6	-0.5	-1.2	0.2	-0.0	-0.7
Number of self-reported non-cancer illnesses	1.4	2.4	9.3	1.9	3.0	0.5	0.1	1.2	0.0	-0.2	-2.1
Average weekly champagne plus white wine intake	0.4	0.5	1.0	0.6	0.4	1.0	-0.5	-0.7	1.0	0.6	0.6
Miserableness	1.1	1.9	3.7	-1.4	-1.4	1.5	-1.9	-0.6	1.2	1.6	-1.0
Guilty feelings	1.0	1.5	3.6	-1.9	-0.3	0.2	-1.9	-0.9	0.6	-1.2	-1.4
Wears glasses or contact lenses	0.3	0.3	1.2	-0.6	-0.2	-0.2	-0.1	-0.3	0.6	1.1	-0.9
Ever taken oral contraceptive pill	0.8	0.9	2.3	-1.5	-0.8	-0.9	0.5	-0.5	-1.5	-0.7	0.1
Hearing aid user	1.0	1.1	4.9	-0.3	2.2	-0.2	-0.3	-1.0	0.1	0.8	-1.4
Mother’s age at death	0.2	0.2	0.5	-0.2	-0.7	0.1	-0.4	0.3	0.7	0.5	-0.2
Financial situation satisfaction	0.4	0.5	1.3	-1.2	-1.0	0.1	0.5	0.5	-0.6	0.9	0.3
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.4	1.5	0.4	-1.1	1.0	1.2	0.1	-0.0	1.1
Commuting to job workplace: Public transport	0.5	0.6	2.0	-0.3	-0.3	0.7	-1.4	-0.4	0.4	-0.6	-1.0
Eye problems/disorders: Glaucoma	0.4	0.4	1.1	0.1	0.2	-1.0	1.0	0.1	-0.9	-0.4	0.7
Medication: Blood pressure	0.2	0.5	1.1	-1.0	0.5	0.5	-1.0	-0.5	0.3	-0.7	-0.7
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.9	-0.3	0.3	0.6	-2.0	0.5	1.5	0.7	0.8
Supplements: Fish oil (including cod liver oil)	0.7	0.9	1.8	1.0	1.0	1.1	0.2	1.1	0.7	0.9	-1.4
High cholesterol (Self-reported)	0.2	0.3	1.4	-1.2	0.2	0.2	0.0	0.1	-0.0	0.2	-1.1
Medication: Bendroflumethiazide	0.1	0.2	0.9	-0.1	0.3	0.3	0.4	-0.1	-0.1	-0.2	-0.9
Medication: Paracetamol	0.4	0.6	2.1	-1.1	0.7	-0.6	-0.0	-0.2	-0.6	-1.4	0.8
Medication: Lisinopril	0.4	0.5	1.6	-0.7	-1.3	0.7	0.3	1.0	0.4	0.3	0.6
Medication: Atorvastatin	1.9	2.3	5.8	-1.3	0.3	1.9	-2.4	-0.8	1.4	1.8	-1.4
Illnesses of father: High blood pressure	1.3	1.6	4.4	-2.1	-1.3	1.2	-1.3	0.7	1.3	0.0	1.1
Alcohol drinker status: Never	0.5	0.6	1.5	0.9	0.5	-0.3	0.6	-0.5	-1.2	-1.1	-0.6
Ever smoked	2.7	4.8	13.8	-0.2	-3.5	-0.2	2.8	3.7	-0.9	-0.9	1.5
Basal metabolic rate	0.2	0.9	2.0	0.4	0.8	-1.4	1.2	-0.2	-0.5	-1.4	0.9
Leg fat percentage (left)	0.2	0.7	2.0	-1.4	-1.4	-0.3	0.0	-1.1	-0.1	0.5	0.4
Arm fat-free mass (left)	0.1	0.6	2.1	0.6	0.3	-1.1	0.8	-0.2	-0.0	-0.8	1.5
Number of operations (self-reported)	1.0	1.5	4.1	-1.1	-0.5	1.0	-1.5	-1.2	1.2	0.2	-2.0
Average weekly beer plus cider intake	0.1	0.1	0.6	-0.1	0.1	0.4	-0.1	-0.3	-0.7	-0.2	0.5
Irritability	0.9	1.5	2.8	-0.9	-1.2	1.5	-1.6	-0.9	1.7	0.8	1.0
Risk taking	0.7	1.0	4.5	0.7	-0.1	0.2	0.1	1.3	0.5	-1.1	2.1
Ever had prostate specific antigen (PSA) test	0.6	0.6	1.7	-1.0	-1.3	-0.3	1.0	-0.2	-1.1	0.2	0.2
Fractured/broken bones in last 5 years	1.3	1.6	4.0	2.0	1.0	1.0	-1.6	0.8	1.8	-0.3	0.8
Age started oral contraceptive pill	0.5	0.6	1.7	1.3	0.9	0.9	-0.6	0.5	0.5	0.2	-0.9
Diastolic blood pressure, automated reading	0.1	0.4	1.9	-0.6	-1.4	0.2	0.4	0.6	-0.4	0.4	0.2
Ever depressed for a whole week	1.4	1.7	3.9	0.5	-1.1	1.6	-1.2	-0.4	2.0	2.0	-0.5
Unable to work because of sickness or disability	0.5	0.6	2.6	-0.7	-0.1	-0.3	0.7	0.6	-0.7	-1.6	-0.4
Commuting to job workplace: Cycle	0.3	0.4	0.7	0.4	-0.7	0.8	-0.4	0.1	0.8	0.8	0.7
Myopia	1.0	1.4	3.7	1.2	0.1	1.6	0.1	1.9	1.5	1.0	-0.4
Vascular/heart problems diagnosed by doctor	0.7	1.9	4.7	2.2	1.6	0.5	0.6	1.4	1.0	1.3	1.6
Cholesterol lowering medication	0.6	0.8	2.7	-1.7	-0.7	0.6	-0.9	0.3	0.8	-0.7	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.5	-0.2	-1.6	-0.0	0.0	1.1	-0.1	-1.1	-0.9
Pain experienced in last month	0.9	1.5	6.8	-0.0	-0.8	-0.4	0.1	-1.5	-1.1	0.8	-2.6
Supplements: Calcium	0.3	0.3	0.7	-0.8	-0.4	0.1	0.8	0.3	-0.8	0.4	-0.5
Basal cell carcinoma (self-reported)	0.4	0.5	1.7	-0.7	-0.5	0.6	-0.7	-1.3	-0.7	0.3	-0.4
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.1	-1.4	-1.3	0.3	-0.6	-1.0	-0.1	-0.8	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.3	1.1	1.0	0.2	-0.5	-0.5	0.5	0.5	-0.3
Heart disease (siblings)	1.1	1.3	4.1	-1.5	-0.9	-0.5	-1.1	-1.1	0.1	-0.7	-2.0
Alcohol drinker status: Previous	0.2	0.2	0.6	-0.1	0.4	0.5	-0.5	0.7	0.1	-0.7	-0.3
Pack years of smoking	0.5	0.7	2.5	-0.9	1.1	-0.4	0.2	0.5	-0.4	0.5	-1.6
Impedance of whole body	0.4	1.8	3.5	1.8	1.0	-0.6	1.5	0.6	-1.4	1.3	-1.9
Leg fat mass (left)	0.1	0.3	0.7	-0.8	-0.5	-0.6	0.1	-0.8	0.1	-0.2	0.4
Arm predicted mass (left)	0.2	0.8	2.2	0.5	0.5	-1.4	1.0	-0.3	-0.2	-1.1	1.5