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chr9:130,855,537-132,601,229

Best TWAS P=5.43e-13 · Best GWAS P=3.17e-12 conditioned to 0.216

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C9orf114	0.06	0.02	bslmm	320	0.02	9.7e-04	-6.8	-5.8	7.0e-09	0.86	0.02	0.98	FALSE
2	CommonMind	Brain Pre-frontal Cortex	ENDOG	0.17	0.19	bslmm	313	0.19	1.3e-22	-6.7	7.2	5.4e-13	-0.89	0.03	0.97	TRUE
3	CommonMind	Brain Pre-frontal Cortex	LRRC8A	0.05	0.04	lasso	2	0.04	7.6e-06	-4.9	5.8	7.4e-09	-0.86	0.10	0.90	FALSE
4	GTEx	Adipose Subcutaneous	ENDOG	0.12	0.07	enet	14	0.11	5.4e-09	-6.7	5.7	1.5e-08	-0.71	0.02	0.97	FALSE
5	GTEx	Brain Cerebellum	ENDOG	0.28	0.15	lasso	4	0.14	5.9e-05	-5.0	6.2	7.6e-10	-0.82	0.06	0.85	FALSE
6	GTEx	Cells Transformed fibroblasts	C9orf114	0.13	0.00	lasso	4	0.02	5.3e-03	-6.9	5.5	3.0e-08	-0.63	0.01	0.96	FALSE
7	GTEx	Colon Transverse	ENDOG	0.14	0.09	lasso	1	0.05	2.7e-03	-6.7	6.7	2.8e-11	-0.96	0.03	0.95	FALSE
8	GTEx	Esophagus Muscularis	PPP2R4	0.09	0.00	lasso	2	0.00	3.4e-01	-6.7	-6.4	1.4e-10	0.95	0.04	0.26	FALSE
9	GTEx	Lung	C9orf114	0.09	0.04	lasso	4	0.06	1.2e-05	-6.9	6.2	6.7e-10	-0.74	0.02	0.98	FALSE
10	GTEx	Nerve Tibial	ENDOG	0.15	0.11	lasso	2	0.10	1.7e-07	-6.9	6.8	8.4e-12	-0.89	0.01	0.99	FALSE
11	GTEx	Pancreas	ENDOG	0.11	0.07	lasso	3	0.06	1.7e-03	-6.6	6.7	1.6e-11	-0.87	0.02	0.90	FALSE
12	GTEx	Skin Sun Exposed Lower leg	ENDOG	0.10	0.10	lasso	3	0.11	3.5e-09	-6.7	6.7	1.6e-11	-0.95	0.04	0.96	FALSE
13	GTEx	Thyroid	ENDOG	0.17	0.13	enet	9	0.14	3.8e-11	-6.9	6.3	3.7e-10	-0.87	0.02	0.98	FALSE
14	METSIM	Adipose	ENDOG	0.09	0.11	lasso	7	0.11	1.2e-15	-6.6	6.7	2.9e-11	-0.88	0.02	0.98	FALSE
15	METSIM	Adipose	TBC1D13	0.03	0.00	blup	302	0.02	5.1e-04	-6.7	-5.4	7.8e-08	0.73	0.04	0.83	FALSE
16	YFS	Blood	ENDOG	0.14	0.19	enet	20	0.23	1.4e-72	-6.7	5.3	1.1e-07	-0.66	0.03	0.97	FALSE
17	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ENDOG	0.05	0.03	blup	33	0.02	5.7e-03	-6.6	5.9	4.5e-09	-0.72	0.02	0.88	FALSE
18	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	ENDOG	0.07	0.05	lasso	4	0.04	4.2e-03	-6.7	5.3	1.2e-07	-0.62	0.02	0.59	FALSE
19	The Cancer Genome Atlas	Colon Adenocarcinoma	ENDOG	0.10	0.09	lasso	5	0.09	8.4e-06	-6.9	6.8	1.1e-11	-0.88	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ENDOG	0.21	0.31	lasso	6	0.32	5.4e-37	-6.6	6.4	1.5e-10	-0.81	0.04	0.96	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	ENDOG	0.11	0.16	lasso	7	0.16	2.5e-18	-6.9	6.2	4.5e-10	-0.76	0.01	0.99	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	LRRC8A	0.03	0.02	blup	35	0.03	2.6e-04	-5.6	5.3	1.5e-07	-0.77	0.01	0.96	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	C9orf114	0.03	0.03	blup	35	0.03	4.3e-04	-6.7	5.5	4.0e-08	-0.64	0.02	0.97	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	ENDOG	0.07	0.08	lasso	5	0.08	1.9e-09	-6.7	5.9	3.2e-09	-0.74	0.03	0.97	FALSE
25	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ENDOG	0.13	0.06	enet	9	0.05	3.4e-03	-5.1	5.5	3.9e-08	-0.66	0.02	0.78	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	ENDOG	0.16	0.12	lasso	8	0.16	3.5e-16	-6.9	5.3	1.2e-07	-0.57	0.01	0.99	FALSE
27	The Cancer Genome Atlas	Stomach Adenocarcinoma	LRRC8A	0.05	0.06	blup	35	0.05	1.8e-04	-6.7	-5.5	3.0e-08	0.83	0.00	0.97	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	ENDOG	0.33	0.32	enet	17	0.34	2.9e-34	-6.9	6.2	5.3e-10	-0.72	0.01	0.99	FALSE