Best TWAS P=2.22e-11 · Best GWAS P=9.21e-10 conditioned to 0.000142
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Colon Adenocarcinoma | PRR5L | 0.19 | 0.00 | blup | 182 | 0.05 | 8.9e-04 | -1.5 | -6.7 | 2.2e-11 | 0.41 | 0.04 | 0.13 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | TRAF6 | 0.09 | 0.04 | blup | 47 | 0.05 | 4.9e-04 | 5.5 | -5.3 | 1.3e-07 | -0.02 | 0.01 | 0.97 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PRR5L | 0.10 | 0.01 | blup | 182 | 0.05 | 4.7e-06 | -6.1 | -5.2 | 1.6e-07 | 0.57 | 0.01 | 0.95 | FALSE |