Hub : Genes

PRR5L

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Lung 0.0973 0.0348 3.2e-03 0.051 NA 0.044 NA 0.054 9.3e-05 NA 2.7e-04 NA 5.5e-05
2 GTEx Skin Not Sun Exposed Suprapubic 0.2040 0.0670 1.5e-03 0.000 NA 0.054 NA 0.003 3.2e-01 NA 6.4e-04 NA 2.0e-01
3 METSIM Adipose 0.0493 0.0202 4.0e-03 0.052 0.010 0.025 0.029 0.040 3.0e-08 9.9e-03 9.2e-05 3.3e-05 1.1e-06
4 TCGA Bladder Urothelial Carcinoma 0.0890 0.0410 4.4e-03 0.004 0.004 -0.003 NA 0.002 1.4e-01 1.3e-01 7.0e-01 NA 2.2e-01
5 TCGA Breast Invasive Carcinoma 0.0312 0.0112 1.5e-04 0.043 0.013 0.031 NA 0.039 2.8e-09 8.4e-04 5.1e-07 NA 2.0e-08
6 TCGA Colon Adenocarcinoma 0.1900 0.0630 1.1e-03 -0.002 0.048 0.000 NA -0.002 4.2e-01 8.9e-04 3.2e-01 NA 4.2e-01
7 TCGA Kidney Renal Clear Cell Carcinoma 0.0956 0.0319 1.4e-04 0.011 0.047 0.040 NA 0.022 2.0e-02 4.7e-06 2.1e-05 NA 1.3e-03
8 TCGA Thyroid Carcinoma 0.0870 0.0300 1.9e-05 0.012 0.050 0.032 NA 0.031 2.3e-02 1.3e-05 4.1e-04 NA 4.9e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.5 0.8 3.3 -0.4 -0.3 -1.8 -0.9 0.4 1.1 -0.7 -0.2
Bipolar Disorder or Schizophrenia 0.2 0.4 1.8 1.4 0.1 -0.6 0.7 0.5 0.5 -0.1 0.2
Depressed Affect (Nagel 2018) 0.4 0.7 2.8 0.4 1.6 -0.4 0.4 -0.1 -0.4 -1.7 -0.2
Depression (Nagel 2018) 0.8 1.2 3.6 -1.1 0.4 -1.9 0.4 1.6 1.2 -0.6 -0.5
Intelligence (Savage-Jansen 2018) 0.1 0.3 1.3 -0.2 -0.1 0.6 -1.2 -0.6 0.1 -0.6 -0.1
Neuroticism (Nagel 2018) 0.2 0.5 2.6 -0.1 1.6 -0.5 0.9 0.1 0.3 -0.1 0.3
Schizophrenia (2018) 0.5 1.1 4.3 2.1 0.3 0.7 1.7 0.3 -0.1 0.5 0.5
Schizophrenia vs Biploar Disorder 2.8 3.7 6.1 2.5 1.4 2.4 2.5 1.0 -0.6 2.0 2.1
Worry (Nagel 2018) 0.2 0.4 1.7 -0.6 0.9 -0.2 1.3 0.4 0.1 -0.1 0.2
Alzheimer’s Disease (in mother) 0.7 0.8 2.3 -0.7 -1.5 -0.9 -0.8 -1.1 -0.5 -0.5 -0.7
Alzheimer’s Disease (in father) 0.3 0.3 1.0 0.2 0.9 1.0 -0.3 -0.2 -0.4 -0.3 0.3
Alzheimer’s Disease (including proxy) 0.5 0.7 1.4 0.2 -0.9 0.5 -0.8 -1.2 -1.1 -0.9 -0.6
Crohns Disease (2017) 0.7 1.6 4.9 0.7 -0.1 -0.8 -1.0 -1.0 -2.2 -1.9 -0.7
Irritable Bowel Disease (IBD) 1.1 2.7 6.5 2.1 0.7 -0.8 -1.8 -2.0 -1.5 -2.5 -0.7
Ulcerative Colitis (UC) 1.3 2.4 5.5 2.3 0.6 -0.5 -2.0 -1.9 -0.3 -2.4 -0.4
Major Depression (MDD) 2.0 2.4 9.6 -1.5 0.1 -1.3 -0.9 -0.6 -1.2 -3.1 -1.8
Reaction Time 0.7 1.3 2.6 0.9 1.0 -0.3 0.4 1.6 0.2 1.6 1.6
Verbal and Numeric Reasoning (VNR) 0.3 0.7 1.9 0.0 -1.2 1.2 -0.7 -1.4 0.0 -0.2 -0.8
Breast Cancer 0.3 0.7 2.6 0.7 -1.0 1.6 1.1 -0.3 -0.5 -0.0 0.0
Ovarian Cancer 2.6 3.4 11.1 1.0 -0.9 -0.3 -3.1 -3.3 0.7 -1.5 -1.3
Prostate Cancer 0.3 0.5 1.0 0.6 0.9 1.0 1.0 0.3 -0.5 -0.5 -0.2
Age at First Birth 0.3 0.4 1.0 0.4 -0.7 -0.1 0.1 1.0 0.9 -0.7 -0.1
Bipolar Disorder (2011) 4.1 3.9 12.0 0.4 0.7 -0.9 -2.5 -2.2 -1.4 -3.5 -2.3
Body Mass Index (BMI) (2010) 0.6 0.8 1.3 1.2 0.1 1.1 -0.8 -0.8 -1.1 -1.1 -0.7
Coronary Artery Disease (CAD) 1.1 1.3 4.2 -1.0 -0.9 -2.1 -0.9 0.6 1.2 -0.3 -1.1
Crohns Disease (2012) 0.7 1.2 4.0 -0.3 -0.2 -1.4 -2.0 -1.2 -0.8 -0.8 -0.5
Mean Putamen Volume 1.4 1.6 3.8 -1.0 -1.9 -1.4 -0.6 -0.3 -0.0 -1.4 -1.8
Fasting Glucose 0.5 0.6 1.7 0.5 1.3 -0.1 -0.1 -0.2 -1.1 -1.0 0.5
HbA1C 0.8 0.9 4.1 -0.5 0.3 -0.4 0.2 0.3 2.0 1.4 0.6
HDL Cholesterol 1.6 2.7 6.3 -1.5 -1.6 0.3 -2.1 -2.1 0.4 -1.5 -2.5
LDL Cholesterol 0.8 1.2 4.6 -0.5 0.8 -0.4 2.1 1.3 -0.6 1.3 0.5
Lupus 0.6 1.0 3.2 -0.8 -1.8 0.4 -0.5 -1.3 0.5 0.1 -1.3
Neuroticism (2016) 0.4 0.6 1.7 -1.1 -0.7 -1.3 0.4 -0.5 0.9 -0.1 -0.0
Primary Biliary Cirrhosis 0.9 1.3 5.2 1.2 2.3 -0.7 0.3 0.2 -1.0 1.3 0.9
Rheumatoid Arthritis 4.6 6.3 24.4 -4.9 -3.0 -2.5 -0.5 0.0 1.9 -0.9 -2.5
Schizophrenia (2014) 0.7 1.6 7.7 2.8 0.4 1.2 1.6 0.2 -0.6 0.2 0.8
Triglycerides 0.9 1.6 4.1 1.2 0.8 -0.4 1.3 1.1 -0.5 2.0 1.7
Type 2 Diabetes (T2D) (2012) 0.5 0.6 2.9 -0.2 -1.7 1.1 -0.2 -0.4 0.1 0.5 -0.6
Ulcerative Colitis 1.8 2.6 6.8 2.6 1.9 -0.6 -2.0 -1.5 1.5 -1.2 0.6
Blood Eosinophil Count 0.4 3.3 9.4 -0.1 -1.5 0.0 0.9 1.0 -3.1 -2.5 -2.7
Blood Platelet Count 0.1 1.1 3.2 -0.0 -0.8 -1.5 0.4 1.8 -1.2 -0.9 0.5
Blood Red Count 0.3 3.0 5.8 1.1 1.4 -2.1 2.3 0.8 -2.4 1.3 1.8
Blood White Count 0.5 3.4 11.4 0.6 -1.0 -0.5 0.9 3.1 -3.4 -1.6 -1.2
Heel T-Score 0.1 0.9 3.5 0.1 -0.3 0.3 0.5 -0.7 0.7 1.9 1.6
BMI 0.2 1.4 3.3 1.6 0.2 1.8 -0.3 -0.1 1.7 1.5 0.4
Height 0.1 2.4 7.6 -0.4 -1.1 0.8 1.4 2.8 2.5 1.1 -0.1
Waist Hip Ratio (WHR) 2.6 11.9 36.4 0.0 1.4 -1.2 5.0 6.0 -0.2 2.4 5.0
Systolic Blood Pressure 0.5 2.5 5.9 2.4 1.9 2.0 1.2 1.1 -1.4 -0.5 1.4
Smoking Status 1.3 3.1 11.7 -0.0 -0.2 1.0 3.4 2.6 -1.9 0.6 1.0
Allergy or Eczema 5.9 15.4 44.8 4.2 0.9 1.2 -2.5 -5.0 -6.7 -5.2 -1.0
Cardiovascular Disease 0.4 1.4 3.8 1.6 0.7 0.8 1.1 0.6 0.3 1.3 2.0
Hypothyroidism (self reported) 1.7 4.0 10.3 1.5 -1.0 2.0 -1.3 -3.1 -3.2 -1.0 -1.5
Respiratory disease 5.0 11.1 27.2 1.8 -0.0 -0.1 -4.1 -5.2 -3.5 -4.3 -3.2
Type 2 Diabetes (T2D) (2018) 1.1 2.0 4.4 1.8 0.4 0.7 1.0 2.0 0.8 1.4 2.1
Lung FEV1/FVC ratio 0.5 2.4 7.0 1.4 -0.7 0.6 1.1 2.5 0.6 1.1 2.6
Lung FVC 0.6 2.8 7.1 -2.5 0.6 -2.2 1.8 2.7 -0.9 -0.4 -0.5
Neuroticism 0.2 0.4 1.1 -0.3 0.8 -0.1 1.1 0.4 0.6 -0.7 0.4
Chronotype (morning person) 0.3 0.8 2.1 1.4 1.1 0.1 0.4 -1.4 0.5 0.3 0.9
Hair Pigment 0.0 0.8 2.6 1.6 0.3 0.4 -0.9 -1.4 0.8 -0.4 0.6
Tanning 0.1 0.6 2.3 0.3 -1.1 -0.1 0.6 0.8 -1.5 0.7 0.1
Hand grip strength (left) 1.0 2.7 5.7 0.1 0.9 0.3 2.2 1.9 1.8 2.4 1.7
Number of treatments/medications taken 1.0 1.7 3.8 1.9 1.7 1.8 0.5 -1.4 -0.8 -0.7 0.8
Average weekly spirits intake 1.7 2.1 8.1 2.8 0.8 0.4 0.1 -0.5 0.3 1.4 2.3
Sensitivity / hurt feelings 0.6 1.0 2.9 0.5 0.8 -0.2 0.1 -0.5 1.7 1.5 1.4
Frequency of depressed mood in last 2 weeks 1.1 1.6 5.4 -1.7 -0.6 -2.3 0.1 0.7 0.4 -1.1 -1.5
Hearing difficulty/problems: Yes 0.3 0.5 1.5 0.9 0.2 0.2 0.4 -0.9 -0.2 1.2 0.9
Relative age of first facial hair 0.3 0.7 1.9 1.4 1.2 -0.7 0.2 -0.0 0.1 -0.7 1.1
Other serious medical condition/disability diagnosed by doctor 1.8 2.4 11.3 -2.1 -3.4 -1.6 -0.3 -0.6 -0.2 0.2 -0.2
Ever used hormone-replacement therapy (HRT) 0.7 0.9 2.7 0.0 1.6 -0.8 0.4 -0.7 1.4 0.7 0.9
Ever had hysterectomy (womb removed) 0.8 0.9 3.6 0.6 0.8 0.5 1.9 0.6 -1.4 -0.4 0.4
Systolic blood pressure, automated reading 1.3 3.8 6.2 2.1 2.5 2.1 2.5 1.9 -0.1 0.6 2.4
Eye problems/disorders: Diabetes related eye disease 1.0 1.1 2.5 1.6 0.8 1.1 0.8 1.6 -0.3 0.5 0.9
Angina 1.2 1.6 4.3 1.4 0.4 0.9 2.1 1.1 -0.7 1.3 1.5
Medication for hormone replacement therapy 0.3 0.3 0.9 -0.3 0.7 -1.0 0.2 -0.3 -0.1 -0.9 -0.1
Vitamin and mineral supplements 0.5 0.7 2.2 0.1 -0.8 1.1 -0.5 -1.5 0.8 -0.4 -0.6
Supplements: Zinc 1.2 1.3 3.5 -1.4 -1.9 -1.8 -0.5 1.3 -0.0 -0.1 -0.3
Medication: Co-codamol 1.1 1.3 4.6 0.8 -0.2 1.5 1.3 0.9 -2.1 -0.4 -0.1
Medication: Metformin 2.2 3.2 8.1 2.2 0.9 0.5 0.9 2.2 1.3 2.1 2.8
Diabetes (father) 1.3 1.6 4.5 0.6 1.2 0.9 1.1 -0.1 -0.3 2.1 2.0
Diabetes (mother) 1.1 1.4 2.9 1.2 1.7 0.3 0.7 0.7 0.2 1.6 1.7
Severe depression (siblings) 1.1 1.2 3.4 1.8 -0.1 1.6 -1.2 -1.4 -0.2 0.1 0.1
Pack years adult smoking proportion 0.5 0.8 3.2 -1.8 -0.2 -0.3 1.4 0.5 0.3 0.8 0.1
Impedance of leg (right) 0.3 1.6 6.7 -0.0 0.8 -0.3 -0.6 -1.4 -2.6 -1.7 0.5
Leg fat-free mass (left) 0.4 2.0 6.0 -0.5 -2.5 0.6 -0.5 0.2 2.4 0.7 -1.6
Trunk fat percentage 0.8 3.1 10.2 1.4 -0.6 1.8 -2.1 -3.2 0.9 -1.4 -1.3
Hand grip strength (right) 0.9 2.6 5.4 0.3 0.9 1.2 2.3 1.7 1.1 2.3 1.9
Townsend deprivation index at recruitment 0.8 1.1 4.0 -0.1 -0.4 0.0 1.8 0.7 -2.0 0.3 -0.9
Current tobacco smoking 0.4 0.7 2.2 -0.9 -0.5 -0.9 0.6 0.9 -1.5 0.3 -0.5
Average weekly fortified wine intake 1.5 1.7 5.7 0.0 1.1 0.5 1.2 0.6 0.3 2.4 2.2
Maternal smoking around birth 1.6 2.3 6.3 -2.5 -2.5 -1.1 0.1 0.3 -0.7 -0.2 -2.0
Fed-up feelings 0.7 1.3 6.6 -0.4 -0.2 -1.0 0.2 -0.2 -0.2 -2.6 -1.4
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 2.7 -1.5 -1.0 -1.7 0.5 0.5 0.7 -1.0 -1.6
Relative age voice broke 0.9 1.3 3.9 -1.1 -0.4 -1.9 1.1 0.6 2.0 0.3 0.1
Taking other prescription medications 2.7 4.1 12.3 0.5 0.1 1.3 -0.9 -2.8 -3.5 -2.8 -1.4
Age when periods started (menarche) 1.3 3.1 8.5 -1.2 -2.7 -1.4 -0.5 0.6 -1.9 -2.9 -1.1
Bilateral oophorectomy (both ovaries removed) 2.9 3.4 6.8 1.6 1.1 1.6 2.6 1.5 -0.8 2.3 2.4
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.6 1.7 0.6 -0.2 1.0 0.3 -1.0 -0.5 0.9 1.3
Tinnitus: Yes, but not now, but have in the past 1.4 1.5 2.6 -1.1 -1.2 -0.2 -1.4 -1.6 1.1 -0.5 -1.6
Qualifications: CSEs or equivalent 0.5 0.7 2.4 -1.5 -0.0 -0.2 0.0 0.6 0.3 1.0 -1.2
Serious illness, injury or assault to yourself 0.5 0.6 2.4 -0.7 -1.3 -0.3 0.0 -0.1 0.3 1.5 -0.4
High blood pressure 1.4 3.8 11.1 2.7 1.4 1.8 1.8 1.3 0.7 1.4 3.3
Hayfever, allergic rhinitis or eczema 5.4 11.7 40.0 3.1 0.2 0.4 -1.8 -4.2 -6.3 -4.6 -1.4
Multivitamins +/- minerals 0.5 0.7 3.0 0.2 0.1 -0.9 0.4 1.7 -0.5 0.5 0.9
Stomach or abdominal pain in last month 0.8 1.0 2.6 -0.4 -0.9 -0.6 0.9 1.6 0.8 1.5 0.5
Supplements: Glucosamine 0.6 0.8 3.8 0.2 0.5 0.3 -0.3 -1.2 0.5 2.0 0.7
Diverticular disease/diverticulitis (self-reported) 1.6 1.9 4.9 1.1 1.3 2.2 1.1 1.8 -0.9 1.0 1.2
Medication: Atenolol 1.5 1.8 3.9 0.5 1.6 -1.1 2.0 0.5 0.7 1.7 1.8
Medication: Levothyroxine sodium 0.4 0.7 2.3 0.2 -0.5 1.3 0.1 -1.0 -1.5 0.1 0.3
Sitting height 0.2 1.2 6.4 -0.1 -2.5 1.1 -0.0 0.8 1.0 0.4 -0.4
Chronic bronchitis/emphysema (father) 0.6 0.7 2.0 -0.4 -1.1 -0.2 0.9 0.4 -1.4 0.1 -1.1
High blood pressure (mother) 1.7 2.4 7.2 0.1 -1.9 -0.7 0.5 1.8 1.2 2.7 1.7
Body mass index (BMI) 0.2 0.7 2.6 0.7 -1.0 1.0 0.1 -0.1 1.6 0.3 -0.3
Impedance of leg (left) 0.3 1.6 4.5 0.4 1.4 -0.3 -0.7 -1.4 -2.1 -1.9 0.7
Leg predicted mass (left) 0.4 2.0 6.2 -0.5 -2.5 0.7 -0.5 0.2 2.3 0.7 -1.6
Trunk fat mass 0.4 1.9 4.1 0.8 -1.2 1.6 -1.5 -2.0 1.7 -0.7 -1.1
Waist circumference 0.2 0.8 1.7 0.5 -0.8 0.7 1.3 1.3 1.0 0.4 0.5
Number of incorrect matches in round 0.9 1.5 3.4 -0.4 1.0 1.1 1.8 1.6 -0.0 1.9 0.3
Past tobacco smoking 1.1 2.0 5.5 -0.9 -1.0 -0.9 -2.3 -2.0 0.4 -1.6 -1.1
Alcohol usually taken with meals 1.6 2.5 5.1 0.8 2.2 2.2 1.0 -0.2 1.0 1.6 2.3
Nervous feelings 0.8 1.5 4.9 -2.2 -0.2 -2.2 0.0 0.0 0.3 -0.6 -1.4
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.3 3.1 -1.4 0.5 -1.8 0.2 1.2 1.7 -0.5 -0.4
Hearing difficulty/problems with background noise 0.1 0.1 0.3 0.5 -0.5 -0.4 -0.0 0.4 -0.1 0.5 -0.1
Hair/balding pattern: Pattern 2 0.5 0.7 3.7 -0.7 1.9 0.1 -0.2 0.4 0.6 0.9 0.0
Had menopause 0.2 0.2 1.3 -0.3 -0.4 0.5 -0.0 -0.4 -0.3 0.0 -1.1
Had other major operations 1.4 1.7 5.4 0.3 1.0 0.5 1.1 0.4 1.6 2.3 1.8
Forced vital capacity (FVC) 0.4 1.4 4.0 -2.0 -0.4 -1.7 0.3 1.0 0.3 -0.8 -1.4
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.6 1.6 1.0 0.2 1.3 0.1 -1.0 -0.4 0.7 0.7
Ever unenthusiastic/disinterested for a whole week 0.9 1.1 2.7 -0.6 -0.9 -1.6 0.0 1.1 0.2 -1.4 -1.4
Qualifications: None of the above 0.7 1.5 5.3 2.1 -0.5 0.1 -0.1 -0.4 -1.2 -2.3 -0.4
Financial difficulties in last 2 years 0.7 0.9 4.7 -0.2 -0.5 -2.2 0.5 0.2 -1.2 0.9 -0.3
Mouth/teeth dental problems 2.4 3.7 11.4 -1.5 -0.3 -1.1 -3.4 -2.9 0.6 -1.5 -2.0
Heart attack 1.9 2.4 6.6 -1.1 -2.0 -0.9 -1.2 -2.0 -0.4 -1.1 -2.6
Allergy 5.5 12.7 32.9 -3.2 0.1 -0.5 2.7 4.7 5.7 4.9 2.2
Pain all over the body in last month 0.9 1.0 2.2 -1.5 -1.2 -0.4 -0.9 0.5 -1.1 -0.5 -1.2
Diabetes (self-reported) 0.4 0.6 2.1 1.5 0.6 0.6 -0.7 0.2 0.5 1.0 0.7
Hayfever/allergic rhinitis (self-reported) 2.0 2.6 5.6 1.9 0.2 0.1 -1.9 -2.1 -2.4 -1.9 -0.6
Medication: Ramipril 0.5 0.6 2.6 0.4 -0.3 -0.1 -0.5 -0.7 1.6 0.5 1.0
Medication: Simvastatin 0.3 0.5 1.5 0.1 0.5 0.9 0.6 -0.8 0.2 1.2 0.1
Fluid intelligence score 0.5 1.0 3.0 1.1 0.2 1.7 -0.8 -1.7 -0.3 -0.2 0.1
Illnesses of siblings 0.8 1.1 5.0 0.8 -0.7 2.2 -0.7 -1.3 -0.2 0.5 0.3
Neuroticism score 0.3 0.6 2.2 -1.0 0.2 -0.4 0.8 -0.3 -0.2 -1.5 -0.8
Weight 0.3 1.3 4.9 0.1 -2.0 0.9 -0.1 0.0 2.2 0.2 -1.0
Impedance of arm (right) 2.0 9.2 27.2 -0.7 0.3 -0.3 -3.9 -5.2 -2.4 -3.7 -3.3
Arm fat percentage (right) 0.4 1.7 4.7 0.8 -1.3 1.3 -1.4 -2.2 0.7 -0.9 -1.4
Trunk fat-free mass 0.6 3.2 8.6 -1.0 -2.5 -0.1 1.1 2.2 2.9 1.9 -0.4
Hip circumference 0.5 2.0 3.8 0.5 -1.2 1.7 -1.1 -1.9 1.7 -0.9 -1.7
Time employed in main current job 0.6 0.7 1.8 0.2 -1.2 -1.3 -1.1 -0.6 1.1 -0.4 0.1
Alcohol intake versus 10 years previously 0.2 0.3 0.8 -0.3 0.6 0.4 0.8 0.9 -0.6 0.5 -0.2
Father’s age at death 0.4 0.5 1.0 0.1 1.0 0.9 0.8 0.3 -0.4 0.8 0.8
Worrier / anxious feelings 0.2 0.4 1.0 -0.4 0.0 -0.2 0.9 0.3 -0.2 1.0 0.9
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 1.7 -1.2 -1.0 -0.3 -0.3 -0.2 -0.4 -0.8 -1.3
Falls in the last year 0.3 0.5 1.1 -1.0 -0.8 0.1 0.8 0.5 -0.8 0.7 -0.1
Hair/balding pattern: Pattern 3 0.8 1.1 4.8 0.3 -0.2 -0.0 2.2 1.0 -0.1 1.2 1.2
Number of live births 0.6 0.8 2.2 0.6 -1.5 0.5 0.6 0.7 -1.3 -1.0 0.1
Forced expiratory volume in 1-second (FEV1) 0.2 0.8 2.0 -1.4 -0.7 -1.4 0.5 1.2 0.4 -0.4 -0.6
Pulse rate 0.8 1.4 4.6 0.9 2.1 1.1 0.5 0.8 -0.2 1.2 1.3
Happiness 0.3 0.3 1.1 -0.2 -0.6 -1.1 0.0 0.1 0.5 -0.8 0.2
Noisy workplace 0.3 0.4 0.9 0.8 -1.0 0.6 0.8 0.4 0.5 0.1 0.2
Qualifications: A levels/AS levels or equivalent 0.1 0.2 0.7 -0.4 -0.2 0.8 -0.5 -0.2 -0.5 0.4 -0.4
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 0.9 -0.6 -0.9 -0.9 -0.6 0.1 0.7 0.4 -0.0
Mouth/teeth dental problems: Dentures 1.5 2.5 9.4 -0.2 -0.7 1.3 3.1 2.4 -0.8 1.2 0.9
Asthma 5.1 10.0 21.2 2.4 0.8 0.5 -4.0 -4.6 -3.2 -4.5 -2.4
Medication: Ibuprofen (e.g. Nurofen) 1.0 1.3 3.7 1.0 1.9 1.3 1.5 0.8 0.6 0.3 0.8
Medication: Cholesterol lowering 0.3 0.4 2.5 0.0 -0.3 0.0 0.4 -1.6 -0.6 0.3 0.1
Depression (self-reported) 0.3 0.4 1.3 -0.8 -0.2 -1.1 0.7 -0.1 0.5 -0.1 -0.3
Medication: Lansoprazole 0.4 0.4 1.2 -0.2 0.1 -1.1 -0.6 0.3 -0.4 -0.6 -1.1
Prospective memory result 0.5 0.6 1.8 -0.3 0.6 0.8 1.1 1.3 0.4 1.0 0.2
Lung cancer (father) 1.3 1.5 4.1 2.0 0.5 1.5 0.4 0.6 1.4 0.9 1.5
Illnesses of mother 1.1 1.4 3.5 -1.6 0.5 -0.3 -0.9 -0.6 0.1 -1.8 -1.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.9 3.0 -1.2 -0.8 -1.7 0.8 1.3 0.2 -0.2 -0.0
Pulse wave Arterial Stiffness index 0.9 1.0 2.4 -0.5 1.2 -1.5 -0.2 1.0 1.2 0.9 1.1
Impedance of arm (left) 1.6 7.6 24.2 0.1 0.7 0.6 -3.2 -4.9 -2.4 -3.5 -2.7
Arm fat mass (right) 0.3 1.3 3.0 0.8 -1.5 1.5 -0.9 -1.1 1.7 0.3 -0.7
Trunk predicted mass 0.6 3.2 7.7 -1.0 -2.5 -0.1 1.1 2.3 2.8 1.9 -0.4
Standing height 0.2 1.5 4.5 -1.4 -2.1 0.1 -0.4 0.1 1.9 0.0 -1.4
Length of working week for main job 1.3 1.4 6.2 0.8 0.2 1.4 1.4 0.4 0.2 2.5 0.4
Exposure to tobacco smoke at home 0.6 0.7 2.6 -0.4 0.5 -0.7 0.6 1.6 0.2 0.3 1.4
Breastfed as a baby 0.2 0.2 0.7 -0.7 0.4 -0.2 0.1 0.3 0.1 -0.8 -0.4
Tense / ‘highly strung’ 0.6 1.0 3.2 -1.1 -1.3 -0.1 0.0 0.2 -0.1 -1.4 -1.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 2.3 -0.4 -0.9 0.4 0.2 0.3 -0.6 -1.5 -0.1
Hair/balding pattern: Pattern 4 0.7 1.7 4.2 -0.6 -1.5 0.3 -1.1 -0.9 -1.5 -1.6 -2.0
Birth weight of first child 0.6 1.0 2.9 0.6 1.7 0.1 -0.4 -0.7 1.2 1.3 1.1
Peak expiratory flow (PEF) 0.6 1.5 5.9 -1.1 -0.5 0.3 -0.4 -0.4 -0.6 -1.9 -2.4
Pulse wave reflection index 0.7 0.9 2.0 -0.3 1.1 -1.4 -0.5 0.4 1.3 -1.2 0.3
Ever highly irritable/argumentative for 2 days 0.7 0.9 3.3 -1.6 0.1 -0.7 -0.2 -0.5 0.2 -0.4 -1.8
Loud music exposure frequency 0.4 0.5 1.4 -0.2 -0.7 0.4 -0.1 1.2 1.0 0.7 -0.3
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 2.5 -1.6 -0.2 -0.1 -0.2 -0.7 0.4 0.6 -1.1
Mouth/teeth dental problems: Bleeding gums 0.7 0.8 2.8 1.1 1.7 0.2 0.6 0.6 1.1 0.3 0.7
Blood clot in the leg (DVT) 1.9 2.4 5.3 1.5 -2.3 0.8 0.9 1.1 1.6 1.6 2.1
Medication: Paracetamol 0.2 0.2 0.9 -0.6 0.2 -0.9 -0.4 -0.3 0.1 -0.7 0.0
Headache pain in last month 0.3 0.5 1.5 0.9 1.2 -0.0 0.8 -0.2 -0.0 -0.7 0.6
Medication for cholesterol, blood pressure or diabetes 0.4 0.6 1.5 -1.2 -0.1 -0.7 -1.2 0.7 0.7 0.5 -0.8
Glaucoma (self-reported) 0.6 0.7 2.1 0.7 0.7 1.5 0.7 -0.9 -1.2 0.2 -0.3
Gout (self-reported) 0.4 0.6 2.0 1.4 -0.3 0.2 0.0 -1.2 -0.1 -0.7 0.5
Hypothyroidism/myxoedema (self-reported) 1.6 3.2 9.6 0.9 -1.0 1.8 -1.1 -2.2 -3.1 -1.5 -1.5
Medication: Amlodipine 0.9 1.3 2.8 0.3 1.3 -1.3 0.2 0.8 1.6 1.1 1.7
Medication: Ventolin 100micrograms inhaler 1.9 2.4 6.5 0.4 -0.1 -0.5 -2.5 -2.1 -1.8 -1.8 -1.1
Birth weight 0.8 1.7 4.1 -0.5 -1.9 0.3 -0.8 -1.8 -1.3 -0.4 -2.0
Chronic bronchitis/emphysema (mother) 0.3 0.3 1.1 -0.3 -0.5 -0.7 -0.3 -0.4 1.1 -0.5 -0.5
High blood pressure (siblings) 0.7 1.0 3.2 -0.7 0.3 -1.8 1.2 1.6 0.3 -0.1 0.2
Forced vital capacity (FVC), Best measure 0.3 1.2 2.9 -1.7 -0.4 -1.7 0.4 0.9 -0.2 -0.9 -1.3
Body fat percentage 0.5 2.0 5.6 1.4 -0.7 1.7 -1.4 -2.4 0.7 -1.4 -1.0
Leg fat percentage (right) 0.1 0.5 1.7 0.9 -0.8 1.3 -0.1 -0.6 0.3 -0.6 -0.1
Arm fat-free mass (right) 0.6 2.9 8.9 0.0 -2.2 0.5 1.0 2.1 3.0 2.0 0.4
Exposure to tobacco smoke outside home 0.5 0.6 1.8 0.5 1.3 1.2 1.0 0.1 -0.6 -0.3 0.2
Comparative body size at age 10 0.3 1.0 3.5 -1.2 -1.0 0.4 -0.6 -0.6 1.9 0.3 -0.9
Number of full brothers 1.8 2.2 5.9 -0.9 -2.4 -0.9 -1.6 -0.8 -1.9 -0.9 -1.7
Worry too long after embarrassment 0.5 0.8 3.0 -1.7 -0.1 -1.2 -0.3 -0.1 0.9 0.6 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 3.5 -0.1 -0.5 0.9 1.9 0.1 -0.3 -0.7 -0.2
Wheeze or whistling in the chest in last year 3.5 6.3 13.5 -0.8 -0.5 -1.5 -2.5 -3.0 -2.3 -3.6 -3.7
Number of children fathered 0.7 0.8 2.0 -0.9 -0.3 -1.4 -0.6 0.4 1.2 1.1 0.7
Reason for reducing amount of alcohol drunk: Health precaution 1.7 2.0 4.6 1.6 1.5 2.1 0.8 0.5 1.3 1.6 1.1
Age at first live birth 0.7 1.2 2.8 0.8 1.4 -0.4 -1.4 -1.1 1.7 -0.6 0.7
Pulse wave peak to peak time 0.9 1.1 3.5 0.5 -1.2 1.9 0.4 -0.9 -1.0 -0.9 -1.0
Health satisfaction 0.6 0.8 1.9 -1.0 -0.4 -1.3 -0.7 -0.6 1.4 0.7 -0.7
Shortness of breath walking on level ground 0.4 0.5 1.5 -0.6 -0.4 -0.9 -0.5 -0.7 0.1 -0.1 -1.2
Qualifications: College or University degree 0.6 1.9 5.5 -0.3 1.1 1.7 -1.2 -2.4 2.1 0.2 -0.2
Eye problems/disorders: None of the above 0.7 0.9 2.6 -0.6 -0.4 -1.6 -1.6 -0.9 -0.1 0.1 -0.7
Mouth/teeth dental problems: Loose teeth 3.2 3.8 11.2 -2.6 -3.3 -1.8 0.0 0.3 2.0 -0.5 -2.2
Emphysema/chronic bronchitis 0.5 0.6 1.9 -0.5 0.6 -1.4 -0.5 -0.7 0.2 -0.0 -1.2
Medication for pain relief, constipation, heartburn 1.4 2.4 4.5 -2.0 -1.4 -1.5 -2.1 -1.3 -0.1 -0.9 -2.1
Neck or shoulder pain in last month 0.9 1.2 4.7 -0.9 -0.1 -1.6 -0.5 -0.2 2.2 1.0 0.4
Medication: Blood pressure 0.9 1.5 3.5 1.9 0.8 1.3 1.7 0.7 0.3 0.0 1.7
Angina (self-reported) 1.1 1.4 2.8 1.6 0.7 0.9 1.7 1.0 -0.6 1.1 1.4
Migraine (self-reported) 0.4 0.6 1.9 -0.6 -1.1 -0.1 1.4 0.5 -0.6 -0.6 0.4
Medication: Ibuprofen 1.2 1.4 3.9 0.7 1.9 1.6 2.0 0.7 0.2 -0.3 0.2
Medication: Allopurinol 0.7 1.0 2.4 1.3 -0.1 0.8 -0.2 -1.6 -0.7 -1.5 -0.2
Medication: Omeprazole 0.9 1.1 4.8 -2.2 -0.4 -1.0 -0.1 1.2 0.7 0.5 -0.6
Medication: Seretide 50 evohaler 0.9 1.1 3.3 -0.1 0.1 -1.8 -0.6 -0.3 -1.5 -1.6 0.4
Mean time to correctly identify matches 1.2 2.2 6.1 0.8 0.9 0.1 1.3 2.5 0.5 2.1 2.0
Heart disease (mother) 0.4 0.5 2.0 -0.6 -1.4 -0.2 -0.4 -0.4 -0.1 0.5 -0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.2 1.4 3.7 1.1 0.2 0.8 -1.3 -0.2 1.4 1.4 1.9
Whole body fat mass 0.3 1.4 2.4 0.8 -1.4 1.6 -1.0 -1.5 1.5 -0.5 -0.9
Leg fat mass (right) 0.2 0.7 1.8 0.7 -1.3 1.4 -0.4 -0.5 1.2 -0.1 -0.4
Arm predicted mass (right) 0.5 2.8 8.0 0.1 -2.2 0.7 0.9 1.9 2.8 2.0 0.4
Pulse rate, automated reading 0.8 2.7 6.8 2.5 2.6 1.2 0.7 0.4 -0.4 1.3 2.2
Alcohol intake frequency. 0.5 1.1 3.1 0.4 -0.1 -0.5 1.8 1.0 -1.2 0.6 1.5
Comparative height size at age 10 0.1 0.7 2.5 -0.2 -1.6 0.5 -0.5 -1.1 0.7 1.0 -0.1
Number of full sisters 0.1 0.1 0.3 0.4 0.1 -0.0 0.3 0.2 -0.6 0.0 -0.1
Suffer from ‘nerves’ 0.8 1.2 2.6 -1.6 0.1 -1.1 0.7 -0.0 -1.1 -1.2 -1.6
Overall health rating 0.8 1.6 4.4 -1.5 -0.9 -0.9 -1.6 -0.8 -0.9 -0.9 -2.1
Chest pain or discomfort 1.2 1.7 4.1 -1.2 -1.1 -1.3 0.9 -0.3 -2.0 -1.1 -1.9
Had major operations 0.1 0.1 0.2 -0.1 -0.3 -0.2 -0.3 -0.5 0.1 0.1 -0.2
Age at last live birth 0.5 0.7 2.3 0.0 -0.4 -0.6 -1.5 -0.6 0.8 -1.2 0.1
Family relationship satisfaction 0.2 0.2 0.5 0.7 -0.7 0.3 0.4 0.3 -0.3 -0.3 -0.3
Leg pain on walking 0.4 0.5 1.1 0.0 1.1 0.6 1.0 -0.3 -0.9 -0.1 -0.6
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 2.8 -0.8 -0.4 -1.7 0.2 0.7 -0.2 0.0 0.5
Commuting to job workplace: Car/motor vehicle 1.7 2.0 7.8 -0.8 0.9 -0.6 0.9 2.8 0.4 1.7 1.5
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 2.0 -0.3 -0.2 1.4 -0.1 0.3 0.3 -0.7 -0.4
Medication: Aspirin 2.2 2.9 4.9 1.9 1.4 1.3 2.2 1.0 -0.0 2.2 2.2
Supplements: Vitamin C 0.6 0.7 1.5 -0.9 -1.2 0.1 -0.5 -1.2 -0.1 -0.3 -1.2
Knee pain experienced in last month 0.6 0.9 2.1 1.4 0.9 1.4 -0.3 -0.5 1.2 -0.1 0.7
Hypertension (Self-reported) 1.1 3.0 9.4 2.3 1.2 1.2 1.7 1.2 0.9 1.0 3.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 1.8 -0.2 1.0 1.3 0.7 0.4 -0.7 0.7 -0.4
Illnesses of father: Heart disease 1.1 1.5 4.6 -0.8 -0.1 -2.1 -2.1 -0.8 0.5 -1.1 -0.7
Illnesses of siblings: Diabetes 2.3 2.8 5.5 -1.2 -1.5 -0.6 -2.3 -2.2 -1.2 -1.5 -2.1
Smoking status: Previous 1.6 2.3 5.9 1.1 1.4 1.2 2.4 1.7 0.1 1.8 1.5
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.2 2.5 -1.5 -1.3 -1.6 -0.6 0.3 1.3 0.2 -0.8
Whole body fat-free mass 0.4 2.5 8.1 -0.6 -2.6 0.3 0.4 1.4 2.9 1.5 -0.8
Leg fat-free mass (right) 0.3 1.9 6.4 -0.3 -2.2 0.5 -0.5 0.3 2.5 0.6 -1.6
Arm fat percentage (left) 0.4 1.8 4.3 0.9 -1.3 1.6 -1.3 -2.1 0.8 -0.6 -1.3
Average weekly red wine intake 0.6 0.8 2.9 0.8 0.5 0.5 -0.5 -0.6 0.7 1.7 1.3
Handedness (chirality/laterality): Left-handed 1.1 1.3 3.1 0.2 1.4 0.3 1.3 0.8 1.1 1.8 1.3
Mood swings 0.6 1.1 3.0 -0.6 -0.8 -0.9 0.5 0.1 -1.7 -1.6 -0.9
Loneliness, isolation 1.9 2.6 10.0 -1.8 -1.0 -0.7 0.1 -1.1 -0.8 -3.2 -2.1
Long-standing illness, disability or infirmity 1.4 2.2 5.6 0.5 -1.2 -0.9 -2.0 -2.4 -1.7 -1.3 -1.1
Ever had bowel cancer screening 1.4 1.6 8.3 -0.6 0.1 -0.8 -0.6 -0.8 2.9 1.4 0.5
Diabetes diagnosed by doctor 0.9 1.4 3.8 1.7 0.3 0.2 0.5 1.3 0.6 1.6 2.0
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.0 3.2 -0.6 -0.3 1.2 1.0 0.1 -1.8 -0.9 -1.1
Friendships satisfaction 0.7 0.8 1.8 1.3 -0.6 0.8 0.5 0.9 0.8 1.1 1.0
Qualifications: nursing, teaching 0.2 0.4 1.3 -0.2 0.4 -0.0 -0.9 -0.2 -0.7 1.1 -0.1
Commuting to job workplace: Walk 0.6 0.6 3.2 0.7 1.8 -0.8 0.1 -0.6 -0.0 -0.3 0.5
Eye problems/disorders: Cataract 0.9 1.1 5.2 -0.1 0.8 0.1 1.0 1.2 2.3 0.5 0.3
Mouth/teeth dental problems: Mouth ulcers 0.7 1.1 3.8 2.0 0.3 0.6 0.6 0.3 -1.6 -0.2 1.3
Medication for cholesterol 0.5 0.8 2.3 -0.6 -1.1 -0.1 -0.7 -0.1 -0.7 -1.2 -1.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.1 1.2 5.5 -1.1 -1.3 -2.3 -0.2 0.9 0.4 -0.7 -0.3
Back pain experienced in last month 1.2 1.7 5.9 -1.3 -2.4 -2.0 0.1 0.7 0.5 -0.1 -1.1
Mineral and other dietary supplements 1.3 1.8 4.2 0.3 -1.7 0.8 -1.4 -0.9 -0.2 -2.1 -2.0
Breast cancer (self-reported) 0.4 0.5 1.3 -1.1 -0.5 0.3 0.3 -0.3 0.5 1.2 -0.5
Asthma (self-reported) 5.0 9.9 23.0 2.2 0.8 0.5 -3.9 -4.8 -3.2 -4.5 -2.4
Osteoporosis (self-reported) 0.6 0.7 1.7 -0.8 -0.2 -0.7 1.0 1.3 -0.8 -1.1 0.1
Osteoarthritis (self-reported) 0.6 0.8 1.9 1.0 -0.0 1.4 1.0 0.6 -1.2 0.3 0.8
Medication: Aspirin 2.3 3.0 5.8 1.7 1.4 1.2 2.1 1.3 0.5 2.3 2.4
Medication: Gliclazide 4.2 4.7 9.6 2.0 0.9 -0.1 2.0 3.1 2.5 1.8 3.1
Illnesses of father: None of the above (group 1) 0.2 0.3 1.0 -0.1 -0.5 0.8 1.0 0.5 0.1 -0.3 -0.0
Smoking status: Current 0.5 0.7 2.8 -0.9 -0.3 -0.5 0.7 1.1 -1.7 0.1 -0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.0 2.0 -0.3 0.1 -1.4 0.5 1.2 1.3 0.8 1.4
Whole body water mass 0.4 2.4 7.8 -0.6 -2.4 0.2 0.4 1.4 2.8 1.6 -0.7
Leg predicted mass (right) 0.3 1.9 6.5 -0.3 -2.2 0.5 -0.5 0.3 2.5 0.7 -1.6
Arm fat mass (left) 0.3 1.4 3.3 0.7 -1.6 1.6 -0.8 -1.1 1.8 0.2 -0.8
Number of self-reported non-cancer illnesses 1.5 2.5 7.0 1.7 1.0 1.2 -0.8 -2.4 -2.6 -1.3 0.1
Average weekly champagne plus white wine intake 1.5 2.0 5.8 -1.1 -0.5 -0.4 -1.5 -1.8 -0.4 -2.4 -1.8
Miserableness 0.4 0.7 2.0 -0.1 1.1 -0.7 0.7 0.1 -0.9 -1.4 -1.0
Guilty feelings 0.6 0.9 2.8 -0.8 0.1 -1.4 1.7 1.0 0.2 0.7 0.8
Wears glasses or contact lenses 0.6 0.7 3.1 -0.6 -0.2 -0.7 -1.8 -0.6 0.5 -0.2 -1.1
Ever taken oral contraceptive pill 1.3 1.5 5.3 0.8 -1.2 0.7 0.8 -0.0 -1.6 -2.3 -0.6
Hearing aid user 0.6 0.7 2.9 -0.9 0.5 -0.0 0.5 1.7 0.3 0.8 -0.9
Mother’s age at death 1.4 1.7 5.2 1.4 2.3 1.6 0.7 1.2 0.1 0.9 0.9
Financial situation satisfaction 1.2 1.4 6.1 -0.2 -0.8 -0.6 -1.0 -0.2 -1.1 -2.5 -1.4
Tinnitus: Yes, now most or all of the time 0.8 0.9 3.2 1.0 -0.4 -0.5 -1.8 -0.4 1.5 0.6 0.6
Commuting to job workplace: Public transport 0.7 0.9 3.0 0.3 -0.5 0.7 -0.7 -1.5 0.6 -0.4 -1.7
Eye problems/disorders: Glaucoma 0.6 0.7 2.2 0.9 0.0 1.5 1.0 -0.2 -1.3 -0.4 0.1
Medication: Blood pressure 0.5 0.9 3.9 0.9 -0.3 -0.1 0.5 0.6 0.6 1.3 2.0
Pain type(s) experienced in last month: Hip pain 0.4 0.5 1.8 -0.3 -1.0 -1.4 0.6 -0.6 -0.1 0.5 0.1
Supplements: Fish oil (including cod liver oil) 1.6 2.1 4.5 -0.7 1.6 -1.4 1.3 1.0 0.7 1.9 2.1
High cholesterol (Self-reported) 0.5 0.9 1.9 1.4 0.9 0.9 0.7 0.1 0.0 1.2 1.4
Medication: Bendroflumethiazide 0.2 0.4 0.9 -0.6 -0.9 0.4 0.7 -0.1 0.1 0.6 1.0
Medication: Paracetamol 0.4 0.6 2.1 -0.3 0.3 -1.0 -0.7 -0.3 0.7 -1.4 -0.2
Medication: Lisinopril 2.7 3.5 7.8 2.4 -1.4 1.2 2.0 2.5 -0.9 -0.1 2.8
Medication: Atorvastatin 1.7 2.1 4.2 2.1 1.5 1.5 1.2 -1.1 -1.4 0.8 1.7
Illnesses of father: High blood pressure 0.7 0.9 4.3 1.2 -0.2 -0.7 0.0 0.9 0.3 0.2 2.1
Alcohol drinker status: Never 0.2 0.3 1.2 0.5 0.0 1.1 0.4 0.1 -0.1 -0.5 0.6
Ever smoked 0.9 1.6 4.3 0.9 0.7 0.4 2.1 2.0 -0.6 1.0 1.2
Basal metabolic rate 0.4 2.1 7.5 -0.4 -2.4 0.6 0.2 1.0 2.7 1.2 -0.8
Leg fat percentage (left) 0.1 0.5 1.7 1.3 -0.4 1.3 -0.0 -0.5 0.5 -0.5 0.2
Arm fat-free mass (left) 0.5 2.4 7.8 -0.3 -2.2 0.3 0.7 1.8 2.8 1.8 0.1
Number of operations (self-reported) 1.0 1.5 3.7 0.2 1.8 1.1 -0.0 -1.9 0.8 1.5 0.8
Average weekly beer plus cider intake 1.3 1.9 4.7 0.3 -1.6 -0.4 -1.0 0.4 -1.5 -2.2 -2.0
Irritability 0.9 1.5 3.7 0.1 -0.8 1.5 -0.1 -1.7 -0.3 -1.9 -1.6
Risk taking 0.8 1.1 3.4 -0.7 -1.1 -1.1 -0.3 0.5 -0.6 -1.9 -1.5
Ever had prostate specific antigen (PSA) test 0.3 0.4 1.1 -0.7 -1.1 -0.1 -0.4 -0.8 0.3 0.2 -0.7
Fractured/broken bones in last 5 years 0.8 1.1 3.8 -0.0 -0.5 -1.0 0.1 0.7 0.7 1.9 1.6
Age started oral contraceptive pill 0.3 0.4 1.8 -0.5 -1.4 -0.2 -0.2 -0.6 0.5 -0.1 -0.6
Diastolic blood pressure, automated reading 0.5 1.5 2.3 1.5 1.4 1.5 1.3 1.4 -0.7 -0.2 1.1
Ever depressed for a whole week 1.1 1.4 3.1 -1.8 -1.5 -1.5 -0.4 0.8 0.9 -0.3 -1.3
Unable to work because of sickness or disability 0.5 0.6 2.5 -0.4 -0.4 -1.6 -0.5 0.3 -0.0 -1.2 -0.6
Commuting to job workplace: Cycle 0.8 1.0 5.5 -0.5 0.7 0.6 -0.5 -2.4 0.0 0.4 -1.0
Myopia 0.2 0.3 1.2 -0.4 0.1 0.4 -1.1 0.1 0.3 0.3 -0.5
Vascular/heart problems diagnosed by doctor 0.9 2.4 6.7 -2.1 -0.8 -1.5 -1.5 -0.8 -0.8 -1.2 -2.6
Cholesterol lowering medication 1.2 1.7 3.7 1.2 0.7 1.3 1.5 1.1 -0.0 1.9 1.7
Medication: Omeprazole (e.g. Zanprol) 1.1 1.3 5.3 -2.3 -0.8 -0.8 -0.1 1.7 0.1 -0.0 -1.1
Pain experienced in last month 0.7 1.2 4.4 -0.1 0.7 0.7 -1.5 -2.1 -0.2 -1.0 -1.1
Supplements: Calcium 1.6 1.8 7.3 -2.7 0.6 -1.8 -0.9 0.1 1.6 -0.0 0.0
Basal cell carcinoma (self-reported) 0.4 0.5 0.9 -0.6 0.4 -0.4 0.9 -0.8 0.6 1.0 0.8
Heart attack/myocardial infarction (self-reported) 1.7 2.2 5.8 -1.2 -2.1 -1.1 -1.2 -1.7 -0.3 -0.9 -2.4
Deep venous thrombosis (DVT) (self-reported) 2.1 2.8 6.2 1.8 -2.5 1.0 1.2 1.2 1.4 1.4 2.3
Heart disease (siblings) 0.3 0.4 1.2 0.9 1.1 -0.6 0.0 -0.6 0.5 -0.1 0.4
Alcohol drinker status: Previous 0.5 0.6 2.7 -0.0 -1.6 0.2 0.6 0.3 -1.3 -0.2 -0.4
Pack years of smoking 0.5 0.7 2.8 -1.7 -0.5 -0.2 1.3 0.4 0.2 0.5 -0.0
Impedance of whole body 1.0 5.2 14.5 0.2 0.8 0.2 -2.4 -3.8 -2.7 -3.2 -1.5
Leg fat mass (left) 0.2 0.8 2.0 0.7 -1.2 1.2 -0.5 -0.5 1.4 -0.1 -0.4
Arm predicted mass (left) 0.4 2.3 7.0 -0.1 -2.0 0.3 0.8 1.7 2.6 1.8 0.3