[Hub]/) : Traits : Allergy or Eczema :

chr11:64,669,105-66,690,454

Best TWAS P=6.65e-17 · Best GWAS P=2.53e-23 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CFL1 0.04 0.00 bslmm 350 0.02 3.3e-03 -4.6 6.0 1.5e-09 -0.40 0.11 0.07 FALSE
2 GTEx Adipose Visceral Omentum MAP3K11 0.08 0.08 lasso 4 0.05 1.7e-03 6.8 7.1 1.7e-12 -0.58 0.48 0.09 FALSE
3 GTEx Artery Aorta MAP3K11 0.15 0.15 lasso 4 0.13 1.8e-07 6.0 5.7 1.5e-08 -0.45 1.00 0.00 FALSE
4 GTEx Artery Aorta SART1 0.08 0.00 enet 23 0.00 2.1e-01 -5.3 5.7 1.4e-08 -0.43 0.07 0.20 FALSE
5 GTEx Artery Tibial EFEMP2 0.11 0.07 lasso 8 0.05 1.3e-04 8.1 -7.4 1.1e-13 0.53 0.85 0.10 FALSE
6 GTEx Artery Tibial BANF1 0.05 0.05 lasso 5 0.06 3.4e-05 -7.1 7.1 1.4e-12 -0.48 0.46 0.04 FALSE
7 GTEx Artery Tibial EIF1AD 0.11 0.00 enet 26 0.01 9.4e-02 8.1 -5.4 5.3e-08 0.48 0.08 0.16 TRUE
8 GTEx Brain Cerebellar Hemisphere EFEMP2 0.35 0.15 enet 5 0.09 2.2e-03 -7.0 -6.7 1.8e-11 0.48 0.33 0.09 TRUE
9 GTEx Brain Cerebellum EFEMP2 0.45 0.40 enet 8 0.39 1.6e-12 -6.6 -6.1 8.0e-10 0.46 1.00 0.00 FALSE
10 GTEx Breast Mammary Tissue FIBP 0.07 0.00 lasso 4 0.01 9.7e-02 3.6 -6.3 2.4e-10 0.50 0.08 0.43 FALSE
11 GTEx Breast Mammary Tissue (Male) MAP3K11 0.23 0.09 lasso 4 0.02 1.4e-01 4.8 5.4 6.4e-08 -0.44 0.09 0.10 FALSE
12 GTEx Cells Transformed fibroblasts EFEMP2 0.06 0.06 lasso 3 0.07 7.8e-06 -5.8 -5.3 1.0e-07 0.40 0.78 0.04 FALSE
13 GTEx Cells Transformed fibroblasts EIF1AD 0.28 0.20 lasso 8 0.21 1.8e-15 -5.5 -6.2 7.1e-10 0.41 1.00 0.00 FALSE
14 GTEx Colon Sigmoid CTSW 0.11 0.06 lasso 3 0.07 1.4e-03 -6.6 6.8 1.0e-11 -0.47 0.24 0.04 FALSE
15 GTEx Colon Sigmoid MAP3K11 0.23 0.05 enet 8 0.08 6.5e-04 6.0 6.6 4.9e-11 -0.58 0.37 0.42 FALSE
16 GTEx Esophagus Gastroesophageal Junction MAP3K11 0.31 0.27 enet 42 0.26 4.9e-10 4.3 5.3 1.5e-07 -0.27 0.97 0.01 FALSE
17 GTEx Esophagus Mucosa EIF1AD 0.15 0.12 lasso 4 0.10 3.2e-07 -6.0 -6.0 2.7e-09 0.40 0.99 0.00 FALSE
18 GTEx Esophagus Muscularis EIF1AD 0.26 0.03 enet 50 0.10 6.6e-07 -5.5 -5.4 6.3e-08 0.33 0.34 0.10 FALSE
19 GTEx Esophagus Muscularis AP001266.1 0.11 0.01 enet 17 0.03 6.1e-03 4.0 5.7 1.3e-08 -0.39 0.14 0.27 FALSE
20 GTEx Lung CFL1 0.04 0.02 lasso 10 0.01 5.8e-02 -5.5 6.1 1.2e-09 -0.40 0.38 0.02 TRUE
21 GTEx Skin Sun Exposed Lower leg EIF1AD 0.08 0.07 lasso 4 0.07 3.6e-06 4.7 -6.2 5.8e-10 0.41 0.98 0.00 FALSE
22 GTEx Stomach MAP3K11 0.09 0.02 lasso 3 0.04 4.4e-03 4.3 6.5 1.0e-10 -0.47 0.20 0.06 FALSE
23 GTEx Thyroid PACS1 0.09 0.04 enet 16 0.09 2.8e-07 5.5 6.5 6.3e-11 -0.34 0.76 0.04 FALSE
24 GTEx Thyroid BANF1 0.10 0.05 enet 17 0.06 4.5e-05 -5.5 5.9 3.9e-09 -0.34 0.99 0.00 FALSE
25 GTEx Thyroid PCNXL3 0.07 0.05 lasso 4 0.03 2.2e-03 6.0 5.9 4.2e-09 -0.48 0.39 0.06 TRUE
26 METSIM Adipose BANF1 0.10 0.06 bslmm 343 0.07 4.9e-10 -5.5 5.4 7.3e-08 -0.32 1.00 0.00 FALSE
27 METSIM Adipose EFEMP2 0.07 0.05 lasso 8 0.04 4.2e-06 -8.1 -8.2 1.8e-16 0.50 1.00 0.00 FALSE
28 NTR Blood BANF1 0.03 0.00 enet 10 0.02 1.1e-06 4.7 5.3 1.0e-07 -0.36 0.18 0.06 TRUE
29 ROSMAP Brain Pre-frontal Cortex EFEMP2 0.08 0.09 enet 13 0.09 6.8e-12 7.5 -7.0 2.2e-12 0.49 1.00 0.00 FALSE
30 ROSMAP Brain Pre-frontal Cortex OVOL1 0.16 0.24 lasso 2 0.24 1.3e-30 6.8 6.7 1.6e-11 -0.61 1.00 0.00 FALSE
31 YFS Blood EFEMP2 0.12 0.07 bslmm 348 0.13 4.3e-41 -7.1 -7.0 2.7e-12 0.36 1.00 0.00 TRUE
32 YFS Blood MUS81 0.04 0.02 blup 348 0.04 6.3e-12 -6.6 7.0 1.9e-12 -0.47 1.00 0.00 FALSE
33 The Cancer Genome Atlas Breast Invasive Carcinoma EFEMP2 0.04 0.02 lasso 5 0.02 1.4e-05 -7.4 -7.3 2.0e-13 0.47 0.09 0.90 FALSE
34 The Cancer Genome Atlas Breast Invasive Carcinoma FIBP 0.03 0.03 blup 45 0.03 2.6e-07 -7.4 -5.7 1.4e-08 0.42 0.28 0.72 FALSE
35 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma EIF1AD 0.07 0.07 enet 5 0.05 1.5e-03 -5.5 -5.6 2.3e-08 0.35 0.01 0.96 FALSE
36 The Cancer Genome Atlas Glioblastoma Multiforme DKFZp761E198 0.14 0.00 blup 39 0.05 1.4e-02 4.0 6.0 2.5e-09 -0.58 0.01 0.24 TRUE
37 The Cancer Genome Atlas Glioblastoma Multiforme SNX32 0.13 0.05 blup 60 0.09 1.1e-03 -1.4 -5.1 2.9e-07 0.41 0.13 0.06 TRUE
38 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BANF1 0.03 0.04 lasso 4 0.03 1.4e-04 -6.0 5.9 3.1e-09 -0.38 0.01 0.99 FALSE
39 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EIF1AD 0.03 0.02 blup 42 0.02 1.5e-03 -5.5 -6.0 1.5e-09 0.35 0.01 0.94 TRUE
40 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DKFZp761E198 0.11 0.02 blup 39 0.03 4.6e-03 -5.9 -6.4 1.2e-10 0.47 0.05 0.21 FALSE
41 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EIF1AD 0.06 0.04 lasso 3 0.05 1.3e-03 -5.6 -6.0 2.5e-09 0.38 0.01 0.98 FALSE
42 The Cancer Genome Atlas Brain Lower Grade Glioma C11orf68 0.03 0.03 lasso 3 0.03 1.1e-04 -5.3 6.3 3.4e-10 -0.37 0.01 0.91 TRUE
43 The Cancer Genome Atlas Brain Lower Grade Glioma DKFZp761E198 0.09 0.06 lasso 3 0.07 2.3e-08 4.0 5.3 1.4e-07 -0.58 0.69 0.29 FALSE
44 The Cancer Genome Atlas Brain Lower Grade Glioma OVOL1 0.03 0.03 blup 36 0.02 8.3e-04 6.8 8.4 6.6e-17 -0.74 0.03 0.82 TRUE
45 The Cancer Genome Atlas Lung Adenocarcinoma BANF1 0.03 0.00 blup 44 0.02 3.9e-03 -6.0 5.4 6.9e-08 -0.29 0.01 0.76 FALSE
46 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EIF1AD 0.03 0.00 blup 42 0.01 2.5e-02 -2.1 -5.2 2.2e-07 0.30 0.01 0.49 FALSE
47 The Cancer Genome Atlas Pancreatic Adenocarcinoma EIF1AD 0.11 0.15 enet 14 0.14 2.9e-06 -6.0 -5.9 3.5e-09 0.40 0.00 0.99 FALSE
48 The Cancer Genome Atlas Pancreatic Adenocarcinoma SNX32 0.40 0.17 blup 60 0.22 1.3e-09 -3.1 -5.4 5.4e-08 0.35 0.98 0.00 FALSE
49 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma DRAP1 0.09 0.10 enet 12 0.09 1.8e-04 -6.0 5.6 1.7e-08 -0.41 0.05 0.34 FALSE
50 The Cancer Genome Atlas Prostate Adenocarcinoma EIF1AD 0.08 0.10 enet 3 0.09 6.0e-10 -6.0 -6.0 2.3e-09 0.39 0.00 1.00 FALSE
51 The Cancer Genome Atlas Soft Tissue Sarcoma EIF1AD 0.05 0.06 blup 42 0.02 1.3e-02 -5.4 -5.6 2.0e-08 0.37 0.01 0.94 FALSE
52 The Cancer Genome Atlas Testicular Germ Cell Tumors RNASEH2C 0.10 0.01 blup 32 0.05 7.9e-03 -3.7 -6.4 1.4e-10 0.57 0.01 0.26 FALSE
53 The Cancer Genome Atlas Thyroid Carcinoma DKFZp761E198 0.06 0.05 blup 39 0.05 3.0e-05 4.0 5.9 4.7e-09 -0.56 0.26 0.41 FALSE