Best TWAS P=7.22e-08 · Best GWAS P=7.42e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | ACY3 | 0.15 | 0.12 | enet | 2 | 0.11 | 1.9e-14 | -5.4 | 5.3 | 1.0e-07 | -1.00 | 0 | 1.00 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ACY3 | 0.18 | 0.15 | lasso | 3 | 0.14 | 3.7e-16 | -5.2 | 5.2 | 2.3e-07 | -0.97 | 0 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | ACY3 | 0.11 | 0.05 | lasso | 3 | 0.04 | 8.3e-05 | -5.4 | 5.4 | 7.2e-08 | -1.00 | 0 | 0.99 | TRUE |