Best TWAS P=3.83e-44 · Best GWAS P=3.28e-71 conditioned to 2.51e-25
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C11orf30 | 0.07 | 0.06 | lasso | 6 | 0.06 | 2.1e-07 | 7.5 | -7.3 | 3.3e-13 | -0.50 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | LRRC32 | 0.21 | 0.00 | enet | 15 | 0.01 | 1.5e-01 | 16.1 | 13.9 | 3.8e-44 | 0.62 | 0.00 | 0.96 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | RP11-111M22.3 | 0.14 | 0.07 | lasso | 2 | 0.04 | 2.7e-04 | 5.5 | -5.5 | 3.7e-08 | -0.34 | 0.42 | 0.13 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | RP11-111M22.3 | 0.21 | 0.05 | enet | 16 | 0.12 | 1.3e-14 | 5.5 | -6.1 | 1.4e-09 | -0.36 | 0.99 | 0.00 | FALSE |
| 5 | YFS | Blood | LRRC32 | 0.02 | 0.00 | bslmm | 481 | 0.00 | 9.1e-02 | 7.6 | -8.8 | 1.2e-18 | -0.55 | 0.17 | 0.41 | FALSE |