Best TWAS P=2.48e-09 · Best GWAS P=8.46e-11 conditioned to 0.00143
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | KIAA0319L | 0.04 | 0.02 | lasso | 7 | 0.01 | 0.00270 | -3.8 | 5.6 | 2.1e-08 | -0.71 | 0.03 | 0.88 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | ZMYM4 | 0.08 | 0.04 | lasso | 3 | 0.03 | 0.00026 | -5.8 | 6.0 | 2.5e-09 | -0.72 | 0.01 | 0.94 | TRUE |