[Hub]/) : Traits : Allergy or Eczema :

chr16:10,325,245-12,138,068

Best TWAS P=1.08e-36 · Best GWAS P=6.1e-45 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum DEXI 0.17 0.02 enet 27 0.03 1.3e-02 -12.6 -9.1 7.7e-20 0.53 0.08 0.84 FALSE
2 GTEx Adipose Visceral Omentum RP11-876N24.5 0.11 0.08 lasso 2 0.10 6.0e-06 -11.5 -10.6 3.5e-26 0.68 0.06 0.92 TRUE
3 GTEx Brain Putamen basal ganglia RMI2 0.48 0.31 lasso 9 0.40 1.7e-10 -2.9 -6.4 1.5e-10 0.34 0.69 0.03 FALSE
4 GTEx Breast Mammary Tissue DEXI 0.12 0.07 enet 14 0.08 6.9e-05 -10.5 -10.3 6.9e-25 0.72 0.06 0.89 TRUE
5 GTEx Breast Mammary Tissue RP11-876N24.5 0.15 0.11 enet 19 0.12 1.4e-06 -10.5 -12.5 9.5e-36 0.73 0.29 0.69 FALSE
6 GTEx Breast Mammary Tissue (Male) RMI2 0.32 0.15 enet 25 0.10 2.9e-03 -2.9 -5.2 1.5e-07 0.26 0.07 0.13 FALSE
7 GTEx Breast Mammary Tissue (Male) DEXI 0.18 0.04 lasso 3 -0.01 4.9e-01 -7.3 -7.8 6.1e-15 0.63 0.03 0.64 FALSE
8 GTEx Breast Mammary Tissue (Male) RP11-876N24.5 0.16 0.24 lasso 2 0.21 1.5e-05 -6.2 -6.8 8.3e-12 0.36 0.07 0.22 FALSE
9 GTEx Breast Mammary Tissue (Female) DEXI 0.13 0.06 lasso 2 0.04 2.0e-02 -11.8 -11.8 5.8e-32 0.79 0.05 0.52 FALSE
10 GTEx Breast Mammary Tissue (Female) RP11-876N24.5 0.22 0.14 enet 11 0.13 1.0e-04 -11.8 -12.5 9.9e-36 0.77 0.14 0.75 FALSE
11 GTEx Cells Transformed fibroblasts DEXI 0.12 0.05 lasso 5 0.08 9.6e-07 -6.7 -9.6 5.8e-22 0.72 0.18 0.82 FALSE
12 GTEx Cells Transformed fibroblasts RP11-876N24.4 0.12 0.04 lasso 5 0.08 2.1e-06 -6.7 -9.6 5.3e-22 0.73 0.18 0.82 TRUE
13 GTEx Esophagus Muscularis RMI2 0.35 0.20 enet 71 0.23 7.4e-14 -2.9 -5.6 2.1e-08 0.10 1.00 0.00 TRUE
14 GTEx Nerve Tibial DEXI 0.11 0.05 enet 7 0.07 1.7e-05 -10.5 -12.7 1.1e-36 0.81 0.64 0.28 TRUE
15 GTEx Pancreas DEXI 0.13 0.06 lasso 4 0.07 5.7e-04 -10.7 -10.8 4.1e-27 0.67 0.18 0.68 TRUE
16 GTEx Pancreas RP11-876N24.4 0.11 0.05 lasso 3 0.04 8.6e-03 -10.7 -10.7 6.2e-27 0.67 0.15 0.67 FALSE
17 GTEx Skin Sun Exposed Lower leg DEXI 0.05 0.06 lasso 2 0.03 7.8e-04 -10.7 -10.4 1.6e-25 0.65 0.70 0.20 FALSE
18 GTEx Testis CLEC16A 0.15 0.00 enet 20 0.01 1.2e-01 -10.3 -11.5 2.1e-30 0.71 0.02 0.92 FALSE
19 GTEx Testis DEXI 0.21 0.11 lasso 3 0.08 2.1e-04 -13.1 -11.7 7.4e-32 0.68 0.29 0.32 FALSE
20 GTEx Testis RP11-876N24.4 0.21 0.06 lasso 5 0.07 6.0e-04 -13.1 -12.5 1.2e-35 0.70 0.22 0.30 FALSE
21 GTEx Thyroid DEXI 0.08 0.00 enet 18 0.03 1.8e-03 -10.7 -9.2 5.1e-20 0.53 0.18 0.65 FALSE
22 GTEx Thyroid RP11-876N24.4 0.06 0.00 enet 17 0.02 1.5e-02 3.3 -7.6 3.3e-14 0.43 0.18 0.32 TRUE
23 GTEx Thyroid RP11-396B14.2 0.12 0.01 lasso 6 0.01 4.0e-02 -13.1 12.5 6.7e-36 -0.80 0.01 0.96 TRUE
24 ROSMAP Brain Pre-frontal Cortex DEXI 0.12 0.12 lasso 6 0.13 5.9e-16 -10.0 -10.8 4.7e-27 0.70 1.00 0.00 FALSE
25 YFS Blood CLEC16A 0.08 0.01 bslmm 627 0.03 1.2e-09 -0.2 6.6 5.1e-11 -0.17 0.93 0.00 TRUE
26 YFS Blood DEXI 0.11 0.15 enet 29 0.16 2.6e-51 -10.0 -9.9 2.5e-23 0.66 1.00 0.00 TRUE
27 The Cancer Genome Atlas Breast Invasive Carcinoma DEXI 0.04 0.02 blup 49 0.04 8.6e-08 -11.5 -10.7 1.1e-26 0.66 0.03 0.97 TRUE
28 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DEXI 0.05 0.02 lasso 4 0.03 1.7e-04 -7.3 -8.4 2.9e-17 0.64 0.02 0.84 FALSE
29 The Cancer Genome Atlas Prostate Adenocarcinoma DEXI 0.09 0.01 blup 49 0.07 8.8e-08 3.2 -6.0 2.0e-09 0.54 0.02 0.87 FALSE
30 The Cancer Genome Atlas Skin Cutaneous Melanoma DEXI 0.20 0.00 blup 49 0.06 1.3e-02 6.1 -5.2 2.4e-07 0.42 0.01 0.10 FALSE
31 The Cancer Genome Atlas Thyroid Carcinoma CLEC16A 0.14 0.06 lasso 4 0.09 6.8e-09 -10.5 7.4 1.6e-13 -0.63 0.22 0.78 FALSE