Best TWAS P=1.99e-08 · Best GWAS P=2.93e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ME2 | 0.08 | 0.06 | lasso | 3 | 0.05 | 6.1e-05 | 5.7 | -5.5 | 4.2e-08 | -0.91 | 0.07 | 0.91 | FALSE |
| 2 | GTEx | Spleen | SMAD4 | 0.33 | 0.10 | enet | 1 | 0.08 | 5.6e-03 | 5.6 | 5.6 | 2.0e-08 | 0.97 | 0.05 | 0.57 | TRUE |
| 3 | YFS | Blood | SMAD4 | 0.03 | 0.03 | lasso | 12 | 0.03 | 1.2e-10 | 5.9 | 5.4 | 8.0e-08 | 0.95 | 0.02 | 0.98 | FALSE |