Best TWAS P=1.03e-07 · Best GWAS P=2.56e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | BRWD1-IT2 | 0.08 | 0.06 | lasso | 5 | 0.06 | 3.9e-05 | 4.8 | 5.3 | 1.4e-07 | 0.92 | 0.04 | 0.94 | FALSE |
2 | GTEx | Lung | PSMG1 | 0.12 | 0.13 | lasso | 5 | 0.12 | 3.4e-09 | 5.0 | -5.3 | 1.0e-07 | -0.98 | 0.02 | 0.98 | TRUE |
3 | GTEx | Stomach | PSMG1 | 0.23 | 0.02 | lasso | 8 | 0.05 | 1.8e-03 | 4.5 | -5.2 | 2.5e-07 | -0.70 | 0.03 | 0.93 | FALSE |