Hub : Genes

BRWD1-IT2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1080 0.0370 1.8e-04 0.081 NA 0.053 NA 0.063 4.0e-07 NA 3.9e-05 NA 7.0e-06
2 GTEx Adipose Visceral Omentum 0.1270 0.0450 1.2e-03 0.011 NA 0.011 NA 0.022 8.4e-02 NA 8.4e-02 NA 2.4e-02
3 GTEx Artery Tibial 0.1547 0.0477 3.6e-05 0.127 NA 0.114 NA 0.122 3.8e-10 NA 3.2e-09 NA 9.0e-10
4 GTEx Brain Cerebellum 0.3650 0.0960 1.7e-04 0.054 NA 0.072 NA 0.165 1.1e-02 NA 3.6e-03 NA 1.3e-05
5 GTEx Cells EBV-transformed lymphocytes 0.2290 0.0860 5.0e-03 0.010 NA 0.009 NA 0.002 1.5e-01 NA 1.6e-01 NA 2.8e-01
6 GTEx Colon Transverse 0.2750 0.0790 4.1e-04 0.008 NA 0.035 NA 0.016 1.3e-01 NA 8.4e-03 NA 5.8e-02
7 GTEx Esophagus Mucosa 0.0810 0.0320 2.6e-03 0.057 NA 0.045 NA 0.065 1.1e-04 NA 5.4e-04 NA 3.9e-05
8 GTEx Muscle Skeletal 0.0598 0.0245 4.6e-03 0.018 NA 0.009 NA 0.013 6.0e-03 NA 4.0e-02 NA 1.7e-02
9 GTEx Nerve Tibial 0.1105 0.0474 4.4e-03 0.084 NA 0.005 NA 0.047 1.5e-06 NA 1.4e-01 NA 3.0e-04
10 GTEx Pancreas 0.1770 0.0670 1.8e-03 0.046 NA 0.013 NA 0.017 5.1e-03 NA 9.3e-02 NA 6.2e-02
11 GTEx Skin Not Sun Exposed Suprapubic 0.1330 0.0510 2.0e-03 0.093 NA 0.059 NA 0.083 9.2e-06 NA 3.8e-04 NA 2.5e-05
12 GTEx Skin Sun Exposed Lower leg 0.0930 0.0350 8.0e-04 0.008 NA 0.042 NA 0.012 6.5e-02 NA 2.1e-04 NA 3.2e-02
13 GTEx Stomach 0.1610 0.0650 9.1e-03 0.102 NA 0.069 NA 0.060 1.3e-05 NA 3.4e-04 NA 8.0e-04
14 GTEx Testis 0.4910 0.0670 6.1e-16 0.452 NA 0.463 NA 0.230 4.4e-22 NA 9.0e-23 NA 1.5e-10
15 GTEx Thyroid 0.1580 0.0410 3.0e-07 0.134 NA 0.132 NA 0.138 1.9e-10 NA 2.8e-10 NA 1.1e-10

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 0.5 0.8 4.1 -0.3 -1.2 -0.5 1.6 0.0 1.4 -0.6 -0.6 -0.5 -0.6 0.1 0.1 -2.0 0.2 -0.5
Bipolar Disorder or Schizophrenia 1.2 2.9 6.9 -1.6 -2.6 -1.5 2.4 -0.3 -0.3 -2.4 -0.9 -1.8 -1.7 -1.4 -1.2 -2.3 1.5 -1.6
Depressed Affect (Nagel 2018) 0.4 0.8 2.0 0.9 0.8 0.8 0.6 0.9 0.7 1.0 0.6 0.7 0.8 0.9 0.2 -1.4 -0.9 1.0
Depression (Nagel 2018) 0.3 0.4 1.0 0.7 0.2 0.4 -0.3 0.6 0.8 0.6 -0.1 0.8 0.5 0.7 -1.0 -0.9 -0.8 0.6
Intelligence (Savage-Jansen 2018) 4.5 13.7 44.2 3.8 6.6 3.5 -0.8 0.9 4.0 5.6 3.1 4.1 4.0 3.6 1.0 0.6 -3.6 4.1
Neuroticism (Nagel 2018) 0.8 1.8 3.0 1.6 1.4 1.5 0.9 0.4 0.7 1.4 1.5 1.4 1.2 1.5 0.8 -1.6 -1.6 1.7
Schizophrenia (2018) 1.4 3.0 6.6 -1.8 -2.4 -1.5 1.6 -0.5 -1.9 -2.6 -0.7 -1.9 -1.7 -1.9 -1.5 -1.3 1.8 -1.6
Schizophrenia vs Biploar Disorder 0.1 0.2 0.5 -0.2 -0.2 0.2 0.3 -0.3 -0.7 -0.5 0.6 -0.1 0.1 -0.4 0.2 0.7 0.3 0.1
Worry (Nagel 2018) 0.1 0.2 1.4 0.2 -0.1 0.2 0.2 -0.4 -1.2 0.0 0.3 -0.1 -0.2 0.1 0.4 -0.3 -0.2 0.2
Alzheimer’s Disease (in mother) 0.4 0.5 3.2 -0.1 -0.8 -0.1 0.7 -0.6 0.9 -0.4 -0.3 0.0 -0.4 -0.1 1.0 -1.8 -0.0 -0.1
Alzheimer’s Disease (in father) 1.0 1.1 2.4 1.2 1.2 1.2 -0.0 0.1 1.5 1.5 0.2 1.2 1.5 1.0 -0.2 0.2 -1.1 1.1
Alzheimer’s Disease (including proxy) 0.3 0.4 1.2 0.6 -0.2 0.7 0.4 -0.6 1.1 0.8 -0.3 0.7 0.5 0.5 0.6 -0.9 -0.8 0.4
Crohns Disease (2017) 0.5 1.2 8.1 0.7 1.5 0.6 -0.6 -0.5 0.4 0.5 1.0 0.5 0.2 0.6 1.2 2.8 -0.8 1.1
Irritable Bowel Disease (IBD) 0.7 1.7 14.1 0.8 1.6 0.5 -0.6 0.8 0.6 0.3 1.3 0.7 0.2 0.9 1.1 3.8 -0.8 1.3
Ulcerative Colitis (UC) 0.4 0.7 6.8 0.2 0.4 0.1 -0.5 1.0 0.2 -0.3 0.6 0.3 -0.3 0.5 0.6 2.6 -0.2 0.6
Major Depression (MDD) 2.6 3.2 5.1 1.8 1.4 1.7 1.3 2.2 1.2 1.9 1.9 2.3 1.4 1.8 2.2 1.1 -1.9 2.1
Reaction Time 2.0 3.9 7.6 -2.3 -0.3 -2.3 -1.4 -2.5 -1.8 -1.5 -2.1 -2.8 -1.9 -2.2 -0.8 1.3 2.5 -2.1
Verbal and Numeric Reasoning (VNR) 1.0 2.4 15.2 0.7 3.9 0.4 -1.5 -1.5 2.0 2.6 0.4 1.0 0.9 0.9 -0.1 -0.0 -0.6 1.1
Breast Cancer 2.1 5.0 8.3 -2.8 -1.8 -2.7 0.0 -2.0 -1.6 -2.9 -1.6 -2.6 -2.2 -2.9 -1.9 -1.6 2.7 -2.5
Ovarian Cancer 1.0 1.4 3.7 -1.3 -1.0 -1.4 0.7 -0.8 -1.9 -1.7 0.4 -1.1 -1.0 -1.2 -0.0 1.5 1.2 -0.9
Prostate Cancer 1.1 1.5 5.9 0.6 2.0 0.3 -1.4 0.1 2.0 1.6 0.2 0.6 0.9 0.6 -1.5 2.4 -0.5 0.8
Age at First Birth 0.5 0.7 2.7 0.7 0.3 0.9 0.3 1.6 -0.8 0.3 1.2 0.5 0.7 0.6 -0.3 -1.4 -0.9 0.8
Bipolar Disorder (2011) 1.0 0.9 5.6 0.8 -1.0 0.9 2.4 0.9 0.6 0.1 1.1 0.7 0.0 0.9 0.8 0.2 -1.0 0.7
Body Mass Index (BMI) (2010) 0.3 0.4 2.4 -0.1 -0.7 -0.2 1.5 -0.5 0.6 -0.7 0.2 -0.2 -0.6 0.1 0.1 -1.2 0.1 -0.1
Coronary Artery Disease (CAD) 1.8 2.1 13.3 0.9 -0.6 0.6 3.6 0.6 2.4 -0.1 1.8 1.2 0.6 1.1 0.7 1.3 -1.2 1.3
Crohns Disease (2012) 1.0 1.7 8.3 1.0 1.7 0.8 -0.8 0.9 1.9 1.3 0.6 0.9 0.6 0.9 1.1 2.9 -0.9 0.9
Mean Putamen Volume 1.6 1.8 5.5 1.5 0.2 1.4 2.1 1.0 0.5 0.6 2.3 1.3 1.2 1.6 0.6 0.4 -1.7 1.7
Fasting Glucose 0.3 0.4 2.5 -0.4 -1.3 -0.5 -0.1 0.1 -0.5 -0.3 -0.3 -0.2 -0.3 -0.2 -1.6 -0.0 0.3 -0.7
HbA1C 0.8 0.8 6.2 0.1 0.3 -0.3 -1.8 0.3 -0.2 -0.4 -0.7 0.2 1.3 0.2 0.7 -2.5 -0.1 -0.1
HDL Cholesterol 0.4 0.6 4.4 0.3 1.4 0.2 -2.1 0.3 0.8 1.0 -0.6 0.4 0.7 0.1 -0.0 0.0 -0.3 0.2
LDL Cholesterol 1.1 1.7 4.2 -1.6 -1.5 -1.6 -0.8 -0.6 -0.3 -2.0 -1.2 -1.7 -1.5 -1.5 -0.8 0.4 1.4 -1.3
Lupus 0.6 0.9 3.2 1.0 0.5 1.0 -0.5 0.7 -0.3 0.8 0.9 0.8 0.2 0.9 1.8 1.2 -1.0 1.1
Neuroticism (2016) 1.0 1.4 1.9 1.2 1.3 0.9 1.4 0.7 1.1 1.2 1.0 1.2 1.1 1.3 1.3 -1.0 -1.3 1.2
Primary Biliary Cirrhosis 0.7 1.0 2.2 -1.2 -0.4 -0.7 -0.8 -0.7 -1.4 -1.0 -1.1 -1.2 -1.5 -1.2 0.1 0.8 1.1 -0.8
Rheumatoid Arthritis 0.4 0.6 1.6 0.8 0.7 0.8 -0.6 1.0 0.6 1.2 -0.0 0.9 0.2 0.9 1.0 0.7 -0.8 0.6
Schizophrenia (2014) 1.3 3.0 6.4 -1.8 -2.5 -1.6 1.3 -0.3 -1.7 -2.3 -1.0 -2.0 -2.0 -1.7 -0.7 -2.2 1.7 -1.7
Triglycerides 2.4 4.0 8.6 -2.3 -2.3 -2.4 0.5 -1.2 -1.6 -2.9 -1.4 -2.3 -2.3 -2.0 -0.6 -2.0 2.4 -2.1
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.3 -0.2 -0.5 -0.5 0.3 -0.1 0.2 -0.5 -0.0 0.2 0.2 -0.1 -0.5 -0.2 0.2 -0.3
Ulcerative Colitis 0.5 0.7 6.0 0.2 1.0 -0.0 -0.3 0.9 0.7 0.1 0.2 0.6 -0.1 0.5 1.2 2.5 -0.1 0.6
Blood Eosinophil Count 0.4 3.3 7.2 -1.8 -2.5 -1.8 1.4 -1.2 -1.9 -2.7 -0.9 -2.1 -2.2 -1.8 -1.0 0.7 1.9 -1.9
Blood Platelet Count 4.9 56.8 83.4 -9.1 -5.7 -8.7 -6.9 -4.3 -7.8 -8.2 -8.8 -8.6 -5.5 -9.0 -2.5 -5.4 9.1 -9.1
Blood Red Count 1.2 11.6 19.1 -4.1 -3.1 -3.9 -0.6 -3.3 -2.4 -4.0 -3.8 -4.0 -3.6 -4.4 -1.9 1.6 4.1 -3.9
Blood White Count 1.6 11.8 18.1 -4.1 -2.6 -4.2 -2.4 -0.7 -3.8 -3.8 -3.6 -4.1 -3.6 -4.0 -2.9 -0.1 4.2 -4.1
Heel T-Score 0.4 2.9 16.0 0.5 0.7 0.5 -4.0 -0.9 -1.7 1.9 -1.3 0.6 0.7 0.6 1.1 -3.8 -0.1 -0.2
BMI 3.6 21.1 41.1 -4.8 -5.7 -4.8 0.4 -1.4 -4.9 -6.4 -4.2 -4.6 -4.7 -5.1 -3.8 -5.2 4.5 -4.7
Height 0.6 11.5 23.0 4.3 -0.9 4.4 3.6 2.1 4.8 3.3 2.8 4.2 1.0 4.7 -0.7 1.5 -4.3 3.4
Waist Hip Ratio (WHR) 0.0 0.2 0.7 -0.3 0.8 -0.0 0.5 0.5 -0.3 -0.1 0.4 -0.6 0.8 -0.4 -0.1 -0.7 0.5 -0.1
Systolic Blood Pressure 1.1 5.5 16.1 2.2 1.4 1.9 3.4 2.1 0.9 0.7 4.0 2.4 2.2 2.3 2.9 1.4 -2.2 2.7
Smoking Status 1.9 4.7 9.0 2.4 2.5 2.5 -0.4 2.1 2.3 3.0 1.6 2.2 1.0 2.6 2.3 1.4 -2.3 2.3
Allergy or Eczema 4.6 12.1 27.7 4.1 4.3 4.1 -0.1 1.5 1.9 5.3 2.9 3.9 4.3 3.9 2.0 0.7 -4.1 4.1
Cardiovascular Disease 0.1 0.2 0.9 0.1 0.7 -0.3 -0.4 -0.5 -0.2 -0.2 -0.0 0.0 0.9 -0.1 0.6 0.9 -0.1 0.3
Hypothyroidism (self reported) 0.9 2.1 4.2 -1.7 -1.6 -1.4 -0.5 -0.8 -2.1 -1.8 -1.6 -1.6 -0.6 -1.8 0.3 -1.3 1.6 -1.7
Respiratory disease 5.0 11.1 24.4 3.9 4.4 3.4 0.1 2.6 1.5 4.9 2.8 3.6 4.7 3.7 1.6 -0.1 -3.7 3.7
Type 2 Diabetes (T2D) (2018) 3.1 5.8 12.1 -2.8 -2.1 -3.0 -2.0 -2.2 -0.6 -2.3 -3.5 -2.6 -2.4 -2.5 -1.8 -1.0 2.8 -2.9
Lung FEV1/FVC ratio 3.1 15.5 34.4 4.3 1.9 4.2 3.9 3.1 3.4 2.3 5.9 3.9 2.2 4.4 2.4 5.3 -4.4 4.9
Lung FVC 0.2 1.1 3.0 -1.1 -0.8 -0.5 -1.0 -1.3 -1.7 -0.9 -0.4 -1.5 -1.3 -1.2 0.3 0.5 1.0 -0.9
Neuroticism 0.4 0.9 1.7 1.1 0.4 0.9 1.3 0.1 0.8 0.7 1.2 0.6 0.5 1.1 1.1 -0.9 -1.1 1.3
Chronotype (morning person) 2.1 4.8 11.6 -2.6 -2.8 -2.0 -0.6 -0.2 -2.9 -3.4 -1.6 -2.9 -1.2 -2.7 -0.3 -1.6 2.4 -2.2
Hair Pigment 0.1 2.5 4.0 -1.7 -1.6 -1.6 0.6 0.5 -1.1 -1.9 -1.4 -1.9 -1.6 -1.9 -2.0 -1.7 1.7 -1.6
Tanning 0.1 0.6 2.8 0.6 -0.8 0.6 1.0 1.0 0.6 -0.1 0.8 0.9 -0.1 0.6 0.6 1.7 -0.7 0.5
Hand grip strength (left) 0.4 1.1 2.7 1.0 0.0 1.3 1.2 0.2 1.0 0.8 1.0 1.2 0.1 0.9 1.6 -1.2 -1.3 1.1
Number of treatments/medications taken 0.1 0.2 1.1 -0.2 0.2 -0.6 -0.7 -0.4 -1.1 -0.5 -0.6 -0.4 0.6 -0.2 0.6 0.2 0.2 -0.1
Average weekly spirits intake 1.1 1.4 3.9 1.2 0.4 1.0 1.6 2.0 0.1 0.6 1.9 1.3 0.9 1.2 0.5 0.3 -1.2 1.3
Sensitivity / hurt feelings 2.4 4.1 7.7 2.4 0.9 2.1 2.8 -0.5 2.3 1.3 2.5 2.3 1.8 2.4 0.8 1.2 -2.6 2.6
Frequency of depressed mood in last 2 weeks 1.6 2.2 6.4 1.7 1.3 1.1 0.3 1.0 2.5 1.7 0.9 1.8 1.7 1.9 -0.7 0.1 -1.8 1.6
Hearing difficulty/problems: Yes 0.7 1.0 3.2 -0.9 -1.2 -1.5 1.1 0.3 0.6 -1.5 -0.7 -0.1 -0.7 -0.5 -1.8 -0.9 0.9 -1.0
Relative age of first facial hair 10.1 20.8 30.4 5.3 4.9 4.8 2.3 4.1 3.3 5.4 4.8 5.4 5.4 5.2 2.7 0.9 -5.2 5.5
Other serious medical condition/disability diagnosed by doctor 0.3 0.3 1.8 0.3 0.4 0.3 -0.7 0.5 -1.4 0.3 -0.7 0.5 0.3 -0.1 0.3 -1.1 -0.1 0.1
Ever used hormone-replacement therapy (HRT) 2.3 2.9 5.5 -1.6 -2.2 -1.3 -1.2 -1.2 -1.6 -2.1 -2.2 -1.8 -2.4 -1.8 -1.2 -0.3 1.8 -1.9
Ever had hysterectomy (womb removed) 0.9 1.0 3.5 1.0 -0.8 1.0 1.8 1.3 -0.3 -0.4 1.9 0.7 0.8 0.8 0.9 0.4 -0.9 0.9
Systolic blood pressure, automated reading 0.5 1.4 8.0 0.2 -0.9 0.0 2.8 1.2 -0.4 -1.9 1.8 0.5 0.2 0.3 1.6 -0.4 -0.3 0.7
Eye problems/disorders: Diabetes related eye disease 1.3 1.4 3.8 -1.2 -1.0 -1.5 0.3 -0.1 -0.5 -1.4 -1.1 -1.4 -1.1 -1.3 -0.6 -1.9 1.5 -1.4
Angina 0.6 0.8 2.3 -0.7 -0.6 -0.6 -1.5 -0.4 -1.3 -0.6 -1.4 -0.8 -0.6 -0.8 0.3 0.4 0.8 -1.0
Medication for hormone replacement therapy 0.6 0.7 1.9 -0.6 -1.4 -0.4 1.0 -0.4 -0.4 -1.3 -0.2 -0.6 -1.4 -0.5 -1.3 0.9 0.4 -0.5
Vitamin and mineral supplements 0.8 1.1 2.4 -1.5 -0.7 -1.4 -0.2 -0.4 -0.9 -1.4 -0.7 -1.2 -1.0 -1.5 -0.1 -0.9 1.3 -1.3
Supplements: Zinc 0.9 1.0 2.2 1.2 -0.0 0.8 -0.6 0.8 1.0 1.2 0.3 1.3 0.7 1.5 -0.3 1.4 -1.3 0.8
Medication: Co-codamol 0.3 0.4 2.4 -0.6 0.6 -0.5 -0.5 0.4 0.5 -0.0 -0.5 -0.4 -0.2 -0.7 1.6 -0.6 0.7 -0.4
Medication: Metformin 1.4 2.0 5.2 -1.4 -1.4 -1.6 -0.7 -1.5 -0.5 -1.3 -2.3 -1.6 -1.4 -1.3 -1.9 -0.2 1.6 -1.5
Diabetes (father) 0.6 0.8 1.7 0.9 0.7 0.6 -1.2 0.4 1.3 1.3 -0.4 0.9 1.0 1.0 1.1 0.1 -0.8 0.5
Diabetes (mother) 0.7 0.9 3.3 0.6 1.3 0.7 -0.6 0.4 0.6 0.9 1.0 0.4 0.4 0.6 1.7 1.8 -0.4 0.9
Severe depression (siblings) 1.5 1.7 3.5 1.5 0.9 1.3 1.1 0.3 1.1 1.0 1.9 1.4 1.1 1.9 0.5 1.3 -1.5 1.7
Pack years adult smoking proportion 1.0 1.5 9.6 0.7 3.1 0.5 -2.3 -0.4 0.5 2.0 -0.0 0.6 1.0 0.5 0.9 0.1 -0.6 0.8
Impedance of leg (right) 1.0 5.1 11.0 2.2 2.6 2.4 -1.0 1.2 2.1 3.0 2.2 2.1 2.2 2.2 2.2 3.3 -1.9 2.1
Leg fat-free mass (left) 0.6 3.1 10.9 -1.0 -3.3 -1.3 1.7 -0.2 0.2 -2.4 -1.4 -1.0 -2.3 -0.9 -2.7 -2.4 0.7 -1.3
Trunk fat percentage 2.4 9.7 20.8 -3.2 -4.3 -3.3 -0.9 -0.6 -2.3 -4.6 -3.6 -3.3 -3.6 -3.4 -2.2 -1.9 3.1 -3.5
Hand grip strength (right) 0.2 0.4 1.4 0.5 -0.1 0.6 1.2 0.5 1.0 0.4 0.6 0.8 -0.3 0.7 0.4 -0.4 -0.8 0.6
Townsend deprivation index at recruitment 1.0 1.4 3.1 1.2 1.3 1.0 -1.4 0.4 1.1 1.8 -0.3 1.2 0.9 1.3 1.6 1.6 -0.9 0.8
Current tobacco smoking 0.6 1.0 3.0 0.9 1.7 1.1 -0.2 0.8 0.8 1.4 0.7 0.9 0.0 0.9 1.3 0.4 -0.8 1.1
Average weekly fortified wine intake 1.1 1.3 2.8 1.4 1.1 0.9 0.2 0.9 -0.0 1.2 0.8 1.7 1.5 1.4 1.1 -1.0 -1.3 1.2
Maternal smoking around birth 0.5 0.8 2.0 1.2 0.2 1.4 -0.4 0.1 1.2 0.9 1.1 0.9 0.2 1.0 0.1 0.5 -1.1 1.0
Fed-up feelings 0.4 0.7 3.0 0.9 -0.1 0.5 1.1 -0.0 1.7 0.3 0.6 0.9 0.4 1.0 -1.3 0.2 -1.0 0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 2.9 0.9 0.1 0.8 0.2 -0.0 1.7 0.5 0.3 0.8 0.1 0.9 -1.6 0.8 -0.8 0.8
Relative age voice broke 6.2 9.5 19.5 3.3 4.4 3.0 1.2 1.7 2.6 4.1 2.9 3.5 3.3 3.2 2.5 1.5 -3.2 3.7
Taking other prescription medications 0.3 0.5 1.6 0.4 1.0 0.3 -0.9 0.9 -1.1 0.7 -0.4 0.4 1.0 0.4 1.3 -0.4 -0.3 0.5
Age when periods started (menarche) 13.0 31.2 48.5 6.1 6.1 6.0 2.4 4.7 5.5 7.0 5.9 6.0 5.3 6.3 4.4 4.2 -5.9 6.4
Bilateral oophorectomy (both ovaries removed) 1.6 1.9 3.9 1.6 1.3 1.4 1.3 0.6 0.9 1.2 1.7 1.3 2.0 1.4 1.3 -1.0 -1.5 1.7
Heel bone mineral density (BMD) T-score, automated (left) 0.9 2.0 12.3 0.2 1.2 -0.1 -3.5 -0.0 -1.3 1.2 -1.2 0.3 0.9 -0.0 -1.4 -3.0 0.0 -0.2
Tinnitus: Yes, but not now, but have in the past 1.6 1.7 5.0 1.4 0.5 1.2 2.2 0.4 1.3 0.7 1.7 1.3 0.8 1.4 0.3 1.9 -1.4 1.6
Qualifications: CSEs or equivalent 4.7 6.2 11.0 -2.9 -1.8 -3.0 -2.0 -2.7 -2.1 -2.4 -2.5 -2.5 -3.3 -2.7 -2.2 0.1 2.7 -2.8
Serious illness, injury or assault to yourself 0.9 1.1 2.4 1.2 1.5 1.1 0.8 1.0 0.7 1.5 0.6 1.2 1.1 1.2 -0.2 0.1 -1.1 1.2
High blood pressure 0.1 0.2 1.6 0.0 0.5 -0.4 -0.4 -0.4 -0.2 -0.5 0.0 0.0 1.3 -0.1 0.9 0.3 0.1 0.2
Hayfever, allergic rhinitis or eczema 4.4 9.4 18.9 3.8 3.2 3.7 0.7 1.2 2.1 4.3 2.8 3.5 3.5 3.7 1.0 1.5 -3.8 3.7
Multivitamins +/- minerals 1.4 1.7 3.8 1.8 1.3 1.5 0.1 0.9 1.2 1.8 0.9 1.7 1.0 1.9 0.3 0.1 -1.5 1.7
Stomach or abdominal pain in last month 2.9 3.6 6.5 2.4 1.3 1.9 1.5 0.9 2.5 2.0 1.9 2.2 1.6 2.5 1.1 0.5 -2.3 2.3
Supplements: Glucosamine 6.3 8.3 16.1 -2.8 -3.4 -2.3 -2.9 -2.4 -1.7 -2.5 -4.0 -3.2 -2.9 -2.9 -2.9 -2.2 2.9 -3.3
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 2.0 -0.1 -0.3 0.2 -0.1 -0.8 0.1 -0.1 -0.2 -0.4 -0.1 -0.3 -0.4 -1.4 0.2 -0.1
Medication: Atenolol 1.4 1.7 4.1 -1.4 -1.4 -1.4 -0.4 -2.0 -0.4 -2.0 -1.2 -1.4 -1.4 -1.4 0.1 0.8 1.3 -1.3
Medication: Levothyroxine sodium 1.6 2.6 4.7 -1.8 -1.8 -1.6 -0.5 -1.1 -1.4 -2.1 -1.7 -1.8 -1.3 -2.1 -0.2 -2.2 1.6 -1.7
Sitting height 0.3 2.1 10.6 0.1 -2.2 0.2 1.4 -0.6 3.3 -0.4 -0.4 0.3 -1.2 0.6 -3.2 0.6 -0.4 -0.4
Chronic bronchitis/emphysema (father) 1.2 1.5 3.4 1.2 1.6 1.3 -0.6 0.8 1.7 1.8 0.4 1.4 1.4 1.4 -0.3 0.7 -1.0 1.1
High blood pressure (mother) 1.3 1.9 3.6 1.6 1.0 1.6 1.7 0.9 0.9 1.1 1.8 1.5 1.4 1.4 0.9 0.8 -1.4 1.9
Body mass index (BMI) 4.0 16.8 29.5 -4.4 -4.8 -4.4 -1.1 -2.0 -3.9 -5.4 -4.6 -4.4 -4.2 -4.6 -3.3 -3.8 4.1 -4.4
Impedance of leg (left) 0.9 4.2 9.8 1.9 2.7 2.3 -1.5 1.2 1.5 2.9 1.8 1.8 1.8 1.9 1.9 3.1 -1.7 1.9
Leg predicted mass (left) 0.6 3.2 11.3 -1.1 -3.4 -1.3 1.8 -0.2 0.2 -2.4 -1.5 -1.0 -2.3 -0.9 -2.7 -2.3 0.7 -1.3
Trunk fat mass 1.9 8.1 18.6 -2.7 -4.3 -2.8 -0.1 -0.6 -1.9 -4.2 -3.2 -2.8 -3.4 -2.9 -2.6 -2.4 2.5 -3.0
Waist circumference 2.5 9.3 18.3 -3.0 -3.6 -3.2 -0.0 -1.0 -2.5 -4.3 -3.2 -3.2 -2.7 -3.2 -3.1 -3.9 2.9 -3.1
Number of incorrect matches in round 2.0 3.3 6.7 -1.8 -2.1 -1.8 -0.9 -1.3 -1.1 -2.0 -2.6 -2.0 -1.6 -2.0 -2.1 -1.3 1.8 -2.2
Past tobacco smoking 5.6 10.3 16.2 -4.0 -3.1 -4.0 -1.2 -2.7 -3.0 -3.9 -2.8 -3.6 -3.1 -4.0 -1.9 -1.4 3.9 -3.7
Alcohol usually taken with meals 0.3 0.6 5.8 -0.2 0.8 -0.2 -0.1 -1.0 0.4 0.1 -0.1 -0.0 0.4 -0.1 0.7 -2.4 0.2 0.0
Nervous feelings 0.2 0.4 1.3 -0.2 -1.0 -0.3 0.7 -0.9 0.0 -0.8 -0.1 -0.4 -1.1 -0.3 -0.5 -0.8 0.2 -0.2
Frequency of tenseness / restlessness in last 2 weeks 2.5 3.9 8.7 2.3 2.3 1.9 0.2 1.7 2.2 2.9 1.2 2.3 2.3 2.4 1.4 -0.1 -2.1 2.0
Hearing difficulty/problems with background noise 1.6 2.6 9.3 -1.1 -2.7 -1.2 2.4 0.3 1.8 -2.2 -0.7 -0.7 -1.3 -0.9 -3.1 -0.2 1.0 -1.2
Hair/balding pattern: Pattern 2 2.6 3.3 5.2 -1.8 -0.9 -2.3 -2.3 -0.6 -2.1 -1.4 -2.2 -1.8 -2.0 -1.6 -1.0 1.9 2.1 -2.0
Had menopause 0.6 0.8 3.8 -0.4 -2.0 -0.7 1.2 0.5 -0.1 -1.7 -0.5 -0.6 -0.7 -0.4 -1.0 0.1 0.4 -0.6
Had other major operations 0.4 0.4 1.9 0.5 0.8 0.4 1.4 0.1 -0.2 0.3 0.8 0.4 0.3 0.2 1.0 -0.9 -0.5 0.7
Forced vital capacity (FVC) 0.9 3.4 5.6 2.1 0.9 2.4 1.3 0.8 2.1 2.3 2.1 2.1 1.1 2.4 0.7 1.9 -2.3 1.9
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.8 11.4 0.4 1.6 0.3 -2.7 0.2 -1.2 1.6 -0.6 0.6 1.2 0.3 -0.3 -3.4 -0.2 0.1
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.8 0.6 0.4 0.3 0.1 1.3 -0.2 0.7 0.3 0.9 0.8 0.8 1.2 0.3 -0.8 0.6
Qualifications: None of the above 1.4 2.9 5.2 -1.8 -2.2 -1.6 -0.3 -0.2 -1.8 -1.7 -2.0 -2.0 -1.9 -2.0 -1.2 0.1 2.0 -2.3
Financial difficulties in last 2 years 1.4 1.8 3.2 1.5 1.7 1.4 -0.2 1.5 1.8 1.6 0.8 1.3 1.4 1.3 1.1 1.2 -1.3 1.5
Mouth/teeth dental problems 2.0 3.1 7.1 -1.7 -2.6 -2.1 0.9 -1.9 -1.1 -2.4 -0.9 -1.5 -1.7 -1.5 -2.7 -0.5 1.5 -1.7
Heart attack 0.1 0.2 0.9 0.3 -0.3 -0.1 1.0 0.0 0.5 -0.2 -0.2 -0.0 -0.1 0.3 0.6 0.7 -0.3 0.2
Allergy 5.8 13.4 28.1 -4.5 -4.4 -4.0 -0.8 -2.4 -2.3 -5.3 -3.2 -4.1 -4.4 -4.4 -0.8 -1.8 4.3 -4.2
Pain all over the body in last month 0.9 1.0 4.4 0.8 0.2 0.3 1.5 2.1 1.6 0.1 1.2 0.8 1.0 0.8 -0.6 0.2 -0.7 0.7
Diabetes (self-reported) 1.7 2.6 7.2 -1.7 -1.0 -1.8 -1.3 -2.0 -0.1 -1.4 -2.7 -1.7 -1.6 -1.6 -1.4 0.3 1.8 -1.9
Hayfever/allergic rhinitis (self-reported) 3.2 4.2 9.0 2.4 2.5 2.5 -1.2 0.3 0.9 2.8 1.9 2.0 3.0 2.4 1.4 -0.1 -2.5 2.2
Medication: Ramipril 0.3 0.4 2.2 0.4 0.3 0.3 0.1 0.5 -1.5 0.4 -0.2 0.5 1.1 0.1 -0.3 1.0 -0.5 0.4
Medication: Simvastatin 1.7 2.5 5.2 -1.6 -1.9 -1.8 -1.2 -0.3 -2.3 -1.9 -1.9 -1.9 -1.2 -1.7 -0.9 -0.3 1.6 -1.8
Fluid intelligence score 0.9 1.8 12.6 0.5 3.5 0.2 -0.8 -1.2 1.7 2.1 0.5 0.8 0.9 0.7 0.8 -0.9 -0.4 0.8
Illnesses of siblings 0.4 0.6 2.6 -0.4 -0.6 -0.3 -0.1 0.8 -1.6 -0.2 -1.0 -0.2 0.1 -0.3 -1.0 -1.2 0.3 -0.8
Neuroticism score 0.6 1.3 5.1 1.3 -0.1 1.1 2.3 0.0 1.5 0.4 1.6 0.8 0.4 1.3 0.0 0.5 -1.3 1.4
Weight 1.2 5.9 15.5 -2.0 -3.9 -2.1 0.8 -0.6 -0.9 -3.4 -2.5 -2.1 -2.9 -2.1 -3.2 -3.0 1.7 -2.2
Impedance of arm (right) 2.7 12.4 16.1 3.7 3.5 3.8 0.9 2.9 3.8 4.0 4.0 3.4 3.2 3.9 3.2 3.7 -3.6 3.8
Arm fat percentage (right) 2.9 11.6 21.2 -3.6 -3.9 -3.7 -1.3 -0.9 -3.4 -4.6 -3.8 -3.7 -3.5 -3.8 -2.4 -3.2 3.4 -3.7
Trunk fat-free mass 0.2 1.4 5.1 0.3 -2.0 0.1 2.0 0.0 0.9 -0.7 -0.1 0.2 -0.8 0.3 -2.1 -2.2 -0.6 0.1
Hip circumference 2.9 12.3 25.8 -3.4 -5.1 -3.7 0.2 -1.4 -2.0 -5.0 -3.6 -3.4 -4.1 -3.4 -4.1 -3.4 3.0 -3.5
Time employed in main current job 0.7 0.8 2.1 -1.0 -0.5 -1.2 -0.7 -0.2 -1.1 -1.4 -0.6 -1.3 -0.4 -1.0 -1.0 0.3 1.0 -0.9
Alcohol intake versus 10 years previously 1.4 2.0 5.9 -1.4 -2.4 -1.7 -0.4 -0.8 -0.2 -2.3 -1.3 -1.4 -1.7 -1.2 -0.3 0.6 1.5 -1.7
Father’s age at death 0.7 0.9 2.1 -0.9 -0.7 -0.6 -0.7 0.6 -1.2 -0.7 -1.5 -1.1 -1.0 -1.0 -0.1 -1.4 0.9 -1.0
Worrier / anxious feelings 0.2 0.4 1.2 0.7 0.5 0.9 1.1 -0.7 0.4 0.7 0.9 0.2 0.1 0.5 0.2 -0.1 -0.8 0.8
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 2.0 -0.3 0.1 -0.7 0.1 -0.9 1.4 -0.5 0.0 -0.4 -0.1 -0.0 -1.0 -0.0 0.3 -0.2
Falls in the last year 0.6 0.9 2.9 0.9 1.7 0.8 -0.9 1.1 1.1 1.3 0.2 0.5 0.9 0.6 1.0 -0.6 -0.6 0.7
Hair/balding pattern: Pattern 3 2.0 3.0 5.7 -2.0 -2.4 -1.8 -0.8 -1.1 -0.9 -1.9 -2.1 -1.8 -1.5 -1.9 -1.6 -1.6 1.8 -2.1
Number of live births 0.3 0.4 1.0 -0.5 0.3 -0.4 -0.9 -0.9 -1.0 -0.0 -0.8 -0.7 -0.4 -0.9 -0.5 0.5 0.7 -0.5
Forced expiratory volume in 1-second (FEV1) 2.2 7.3 11.4 3.0 1.4 3.1 2.1 1.2 2.8 2.8 3.4 3.0 1.8 3.3 1.1 3.4 -3.3 3.0
Pulse rate 4.3 7.2 12.7 3.0 2.3 3.1 2.7 1.6 2.5 2.6 3.6 2.9 2.6 3.0 1.7 1.4 -2.9 3.2
Happiness 0.4 0.5 1.3 0.1 -1.1 0.5 1.1 1.1 -0.0 -0.3 0.4 0.0 -0.8 0.1 0.9 1.0 -0.4 0.2
Noisy workplace 0.5 0.6 3.2 0.5 0.6 0.5 0.4 1.0 1.8 0.6 0.6 0.2 0.5 0.6 1.2 0.9 -0.5 0.7
Qualifications: A levels/AS levels or equivalent 2.4 5.2 13.0 2.2 3.6 1.6 0.4 1.2 2.3 3.2 1.9 2.6 3.1 2.6 0.6 -1.3 -2.4 2.4
Serious illness, injury or assault of a close relative in last 2 years 1.2 1.4 3.2 1.3 1.2 1.2 -1.2 1.4 1.1 1.8 0.3 1.3 1.1 1.2 0.4 0.7 -1.3 1.2
Mouth/teeth dental problems: Dentures 2.0 3.4 8.6 2.1 2.0 2.3 -0.0 1.5 1.1 2.2 1.7 1.5 1.8 1.8 2.9 1.1 -1.8 2.0
Asthma 1.8 3.6 6.9 2.3 2.1 1.9 0.4 2.1 0.1 2.6 1.8 2.2 2.5 2.3 -0.1 -0.0 -2.1 2.2
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.6 0.4 1.3 0.5 -0.5 -0.1 0.2 1.2 0.1 0.3 0.7 0.6 1.3 -0.5 -0.4 0.5
Medication: Cholesterol lowering 3.0 4.6 7.8 -2.2 -2.8 -2.3 -1.8 -1.4 -2.4 -2.5 -2.6 -2.4 -1.7 -2.3 -0.9 1.3 2.3 -2.4
Depression (self-reported) 1.5 1.8 3.4 1.2 1.8 1.3 0.7 1.2 -0.2 1.7 1.1 1.1 1.8 1.2 1.8 -1.4 -1.1 1.4
Medication: Lansoprazole 2.1 2.4 4.0 2.0 1.2 1.7 1.6 1.9 0.9 1.9 1.6 1.4 1.4 1.9 0.3 0.4 -1.8 1.9
Prospective memory result 0.3 0.4 1.9 0.2 -0.2 0.2 -1.4 0.0 -1.0 0.5 -0.8 0.4 0.4 0.1 0.2 -1.1 -0.2 -0.1
Lung cancer (father) 0.5 0.6 1.2 -0.9 0.0 -0.9 -0.3 -1.1 -0.7 -1.0 -0.5 -0.9 -1.0 -1.0 -0.2 0.0 1.0 -0.7
Illnesses of mother 1.2 1.5 5.8 -1.2 0.4 -1.1 -2.4 -1.6 -1.0 -0.2 -1.5 -1.2 -0.3 -1.1 -0.4 -1.0 1.1 -1.4
Forced expiratory volume in 1-second (FEV1), Best measure 1.9 6.0 12.2 2.8 1.5 2.9 1.3 0.7 2.9 2.7 2.8 2.5 1.5 2.9 1.0 3.5 -2.9 2.8
Pulse wave Arterial Stiffness index 0.9 1.1 2.5 1.4 0.3 1.5 -0.2 1.2 1.0 1.6 0.3 1.2 0.5 1.4 1.0 0.0 -1.2 1.0
Impedance of arm (left) 1.6 7.5 15.0 2.7 2.7 2.8 0.4 2.7 2.9 2.9 3.2 2.6 2.3 2.9 2.3 3.9 -2.5 2.8
Arm fat mass (right) 3.0 12.2 22.6 -3.6 -4.4 -3.7 -0.8 -1.4 -2.7 -4.8 -3.9 -3.6 -3.9 -3.8 -3.2 -3.4 3.3 -3.7
Trunk predicted mass 0.2 1.4 4.9 0.1 -2.1 0.0 1.9 -0.1 0.9 -0.8 -0.2 0.1 -1.0 0.2 -2.2 -2.2 -0.5 -0.0
Standing height 1.6 15.5 38.6 4.7 1.1 4.5 4.1 2.8 6.2 3.7 4.0 4.6 2.2 5.0 -0.1 1.9 -4.8 4.2
Length of working week for main job 2.8 3.1 5.0 1.9 1.8 2.2 0.7 0.9 1.0 2.0 1.9 2.0 2.0 1.9 1.9 0.6 -2.0 2.0
Exposure to tobacco smoke at home 0.4 0.4 1.7 -0.2 -1.0 -0.1 -0.6 -0.3 -1.3 -0.3 -0.7 -0.1 -0.2 -0.4 -1.0 -0.8 0.3 -0.4
Breastfed as a baby 0.4 0.5 4.0 0.2 0.4 0.1 -2.0 0.7 -0.4 0.6 -0.8 0.2 0.4 0.1 -1.0 -0.1 -0.1 0.0
Tense / ‘highly strung’ 0.2 0.3 0.7 0.7 0.3 0.7 0.3 -0.8 0.6 0.7 0.6 0.2 0.3 0.6 -0.1 -0.5 -0.6 0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 2.6 0.8 -0.0 0.8 1.6 0.6 0.3 -0.0 1.2 0.5 0.7 0.8 -0.7 1.6 -0.9 1.0
Hair/balding pattern: Pattern 4 0.3 0.7 3.2 -0.1 1.1 0.4 1.5 -1.0 0.5 0.1 1.4 0.0 0.4 -0.1 1.8 -0.2 0.1 0.5
Birth weight of first child 0.3 0.6 1.7 0.8 0.8 0.7 -1.3 0.0 -0.7 0.9 0.1 0.9 0.4 0.8 -0.3 0.7 -0.8 0.9
Peak expiratory flow (PEF) 3.2 7.3 12.2 3.3 1.6 3.4 2.0 1.8 2.5 2.8 3.5 3.0 1.9 3.4 1.6 1.8 -3.4 3.2
Pulse wave reflection index 0.2 0.3 1.3 -0.4 -0.7 -0.3 -0.9 0.2 0.1 -0.1 -1.1 -0.3 -0.3 -0.2 -0.6 0.4 0.2 -0.7
Ever highly irritable/argumentative for 2 days 1.8 2.1 4.5 1.6 1.3 1.5 -0.8 1.4 0.3 2.1 0.5 2.1 1.5 1.7 1.6 0.7 -1.7 1.5
Loud music exposure frequency 0.9 1.0 2.9 -1.2 -0.8 -0.5 1.0 -0.5 -1.0 -1.0 -0.4 -0.9 -1.7 -1.3 0.2 0.9 1.3 -0.8
Qualifications: O levels/GCSEs or equivalent 5.3 8.5 21.7 3.1 4.7 2.5 -0.1 1.2 1.9 4.3 2.8 3.6 3.4 3.3 1.3 -0.4 -3.2 3.3
Mouth/teeth dental problems: Bleeding gums 0.6 0.8 2.6 0.2 1.5 0.6 -1.6 -0.1 1.3 1.1 -0.7 -0.0 0.2 0.1 0.3 -1.6 -0.1 0.1
Blood clot in the leg (DVT) 0.3 0.3 1.3 0.4 1.0 0.2 0.9 0.5 1.1 0.6 0.3 0.2 0.3 0.2 0.6 0.5 -0.2 0.3
Medication: Paracetamol 0.5 0.8 4.1 0.1 2.0 -0.2 -1.9 1.2 0.5 1.1 -0.8 0.2 0.7 0.1 0.7 0.4 0.1 0.3
Headache pain in last month 2.0 3.5 6.7 2.0 2.6 2.2 -0.3 0.1 1.8 2.3 1.5 1.5 2.0 1.8 2.5 1.1 -1.9 2.2
Medication for cholesterol, blood pressure or diabetes 1.7 2.9 5.2 1.9 1.7 2.0 1.5 1.2 2.1 2.3 1.9 1.9 1.1 1.9 0.2 -0.6 -1.9 1.8
Glaucoma (self-reported) 1.6 1.9 4.0 1.5 0.0 1.4 2.0 1.8 0.1 0.4 1.8 1.6 1.7 1.5 0.3 0.6 -1.4 1.7
Gout (self-reported) 1.6 2.3 4.3 -1.8 -0.5 -1.8 -2.1 -0.7 -1.9 -1.3 -1.4 -1.7 -1.4 -1.5 -0.8 -0.9 1.7 -1.7
Hypothyroidism/myxoedema (self-reported) 1.0 2.0 4.9 -1.5 -1.8 -1.2 -0.0 -0.9 -1.2 -2.1 -1.6 -1.3 -0.8 -1.7 0.2 -2.2 1.3 -1.4
Medication: Amlodipine 0.7 0.9 4.1 -0.7 -0.8 -0.5 -0.3 -2.0 -0.7 -1.3 -0.4 -0.9 -1.1 -0.9 -0.1 1.6 0.7 -0.4
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.1 0.7 -0.0 0.6 0.2 0.7 0.6 0.7 0.6 0.6 0.6 0.8 -0.5 -1.1 -0.8 0.4
Birth weight 1.1 2.5 6.8 1.9 2.0 2.0 -0.9 1.2 0.6 2.6 0.9 1.6 1.6 1.8 -0.6 -0.1 -1.9 1.7
Chronic bronchitis/emphysema (mother) 0.9 1.1 2.2 1.3 0.7 1.3 1.4 -0.1 1.3 1.0 1.5 0.7 0.7 1.1 -0.2 0.6 -1.2 1.3
High blood pressure (siblings) 1.5 2.1 3.3 1.6 1.5 1.6 0.1 0.1 1.8 1.6 1.5 1.6 1.6 1.5 0.9 1.8 -1.5 1.8
Forced vital capacity (FVC), Best measure 0.5 1.8 4.0 1.5 0.7 1.8 0.1 0.1 1.8 1.9 1.0 1.3 0.4 1.5 0.4 2.0 -1.6 1.3
Body fat percentage 3.2 12.5 23.3 -3.7 -4.3 -3.7 -1.4 -1.1 -3.2 -4.8 -4.1 -3.8 -3.8 -4.0 -2.5 -2.8 3.6 -3.9
Leg fat percentage (right) 3.3 12.1 20.0 -3.6 -4.1 -3.5 -1.6 -1.6 -3.6 -4.5 -4.0 -3.7 -3.5 -4.0 -2.2 -3.6 3.5 -3.8
Arm fat-free mass (right) 0.7 3.6 11.5 -1.3 -3.4 -1.4 1.3 -0.9 -0.3 -2.3 -1.8 -1.2 -2.4 -1.2 -3.0 -2.6 1.1 -1.6
Exposure to tobacco smoke outside home 0.1 0.1 0.5 -0.4 0.7 -0.1 0.6 -0.5 -0.2 -0.3 -0.0 -0.3 -0.3 -0.4 0.3 -0.4 0.3 0.0
Comparative body size at age 10 1.2 3.3 9.3 1.9 0.5 2.1 1.2 2.4 0.8 1.2 1.0 1.8 2.1 1.6 2.0 -3.0 -2.1 1.8
Number of full brothers 1.3 1.7 3.2 1.3 1.8 1.3 0.0 1.4 0.0 1.7 1.2 1.4 1.3 1.2 0.9 1.6 -1.2 1.5
Worry too long after embarrassment 1.1 1.8 7.6 1.1 -0.1 1.1 2.8 -0.1 2.6 0.1 2.0 0.7 0.0 1.2 -0.1 0.9 -1.3 1.3
Seen a psychiatrist for nerves, anxiety, tension or depression 4.9 6.3 11.4 3.1 1.9 2.6 2.4 1.3 2.1 2.2 3.0 2.6 3.4 3.1 1.3 -0.4 -3.1 3.1
Wheeze or whistling in the chest in last year 1.4 2.5 5.7 1.8 2.4 1.5 0.3 0.5 2.1 2.2 1.3 1.4 1.1 1.9 0.3 1.1 -1.6 1.9
Number of children fathered 1.4 1.6 8.0 0.8 2.8 0.7 -0.4 1.2 -0.9 1.4 1.1 0.8 1.8 0.7 1.5 -0.8 -0.7 1.1
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 1.8 -0.8 -1.3 -0.6 -0.4 -1.3 -0.7 -1.2 -0.5 -0.7 -0.4 -0.5 0.3 -0.1 0.7 -0.7
Age at first live birth 0.5 0.9 1.7 -1.2 -0.1 -1.3 0.6 -0.3 1.3 -1.2 -0.6 -0.9 -1.2 -1.0 -0.1 -1.0 1.1 -0.9
Pulse wave peak to peak time 0.6 0.7 1.7 -1.1 -0.3 -1.2 0.2 -1.1 -0.8 -1.3 -0.1 -1.0 -0.4 -1.1 -0.9 -0.1 1.0 -0.7
Health satisfaction 0.3 0.4 3.6 0.0 -0.6 -0.0 0.2 -0.8 0.5 -0.3 -0.2 -0.2 -0.2 0.1 -0.7 1.9 -0.1 -0.1
Shortness of breath walking on level ground 0.7 0.8 4.3 0.8 -0.3 0.8 2.1 -0.6 1.3 -0.1 1.2 0.6 0.5 0.7 0.0 0.3 -0.9 0.8
Qualifications: College or University degree 0.6 1.8 5.3 1.0 1.6 1.0 2.3 0.7 1.4 0.9 1.9 1.1 1.2 1.2 1.4 -0.6 -1.2 1.5
Eye problems/disorders: None of the above 0.3 0.4 1.2 0.3 0.4 0.5 0.3 -0.1 0.8 1.0 0.5 0.4 -0.4 0.7 0.7 1.1 -0.4 0.3
Mouth/teeth dental problems: Loose teeth 0.2 0.2 1.8 0.5 0.5 0.3 -0.0 -0.2 0.1 0.3 0.3 0.4 0.2 0.4 -0.5 1.3 -0.4 0.5
Emphysema/chronic bronchitis 1.4 1.6 2.8 1.2 1.7 1.1 0.8 0.2 1.7 1.5 1.4 1.1 1.2 1.2 0.0 1.7 -1.2 1.3
Medication for pain relief, constipation, heartburn 0.5 0.8 3.6 0.5 -1.2 0.8 1.9 -0.3 1.4 -0.2 1.2 0.8 -0.2 0.6 -0.9 0.3 -0.6 0.5
Neck or shoulder pain in last month 0.6 0.9 4.3 -0.5 0.4 -0.5 -2.1 -1.9 -0.6 0.5 -1.7 -0.4 -0.2 -0.5 -0.2 -0.2 0.6 -0.7
Medication: Blood pressure 0.6 1.1 2.0 -1.2 0.1 -1.4 -1.3 -1.3 -1.3 -1.4 -0.9 -1.1 0.0 -1.2 -0.1 0.6 1.1 -0.8
Angina (self-reported) 0.5 0.6 2.3 -0.6 -0.5 -0.4 -1.5 -0.2 -1.4 -0.4 -1.3 -0.6 -0.3 -0.6 0.6 0.2 0.7 -0.8
Migraine (self-reported) 1.5 1.9 3.6 1.4 1.6 1.4 0.4 1.8 1.0 1.9 1.0 1.7 1.3 1.3 1.5 0.2 -1.3 1.5
Medication: Ibuprofen 0.8 1.0 3.0 0.7 1.7 0.9 -0.8 -0.4 0.8 1.7 0.2 0.7 0.8 0.8 1.7 0.1 -0.6 0.8
Medication: Allopurinol 6.3 8.3 13.9 -3.6 -1.8 -3.4 -2.6 -1.5 -3.2 -3.0 -3.0 -3.7 -2.9 -3.5 -1.8 -0.8 3.4 -3.3
Medication: Omeprazole 3.4 4.0 10.5 -2.0 -1.8 -2.0 -0.7 -0.3 -3.2 -2.5 -2.0 -2.1 -1.3 -2.3 -2.1 -1.9 2.0 -2.1
Medication: Seretide 50 evohaler 1.8 2.0 7.8 1.3 2.8 1.2 -0.7 0.7 1.4 2.5 0.6 1.0 1.7 1.3 1.1 -0.6 -1.1 1.3
Mean time to correctly identify matches 4.9 9.3 15.6 -3.5 -1.6 -3.6 -2.3 -3.3 -2.9 -2.9 -3.6 -3.9 -2.9 -3.5 -1.8 -0.1 3.7 -3.5
Heart disease (mother) 1.5 1.8 5.6 1.3 0.7 1.6 1.3 2.4 1.5 1.3 0.8 1.5 0.5 1.2 0.9 1.6 -1.2 1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.6 1.9 3.7 1.5 1.7 1.4 0.9 0.9 1.2 1.9 1.5 1.5 1.8 1.7 0.2 -0.7 -1.4 1.4
Whole body fat mass 2.9 12.1 21.9 -3.5 -4.5 -3.5 -0.9 -1.2 -2.9 -4.7 -4.0 -3.6 -4.0 -3.7 -3.1 -3.3 3.3 -3.7
Leg fat mass (right) 3.3 12.9 23.3 -3.6 -4.8 -3.5 -1.1 -1.5 -2.9 -4.7 -4.1 -3.7 -4.1 -3.9 -3.0 -3.6 3.4 -3.9
Arm predicted mass (right) 1.0 4.9 11.7 -1.8 -3.4 -1.9 0.6 -1.3 -0.6 -2.6 -2.5 -1.7 -2.7 -1.8 -3.3 -2.9 1.5 -2.1
Pulse rate, automated reading 4.0 13.0 20.2 4.2 3.7 4.2 1.9 1.7 2.7 3.8 4.5 4.0 3.8 4.2 2.3 2.6 -4.1 4.4
Alcohol intake frequency. 0.6 1.3 5.0 -1.0 0.9 -1.4 -1.4 -1.4 -0.4 -0.2 -1.4 -0.7 -0.2 -1.0 -1.0 -2.2 1.2 -0.8
Comparative height size at age 10 0.4 2.4 10.3 -0.7 -3.2 -0.8 0.6 -1.5 0.9 -1.4 -1.4 -0.6 -2.0 -0.4 -2.5 -2.2 0.5 -1.4
Number of full sisters 0.3 0.3 2.2 0.0 0.5 -0.0 0.6 -0.1 -0.5 0.3 0.4 0.3 0.1 0.1 -1.5 1.3 0.0 0.2
Suffer from ‘nerves’ 0.1 0.1 0.4 0.4 0.4 0.1 -0.6 -0.7 -0.3 0.5 0.1 0.2 0.3 0.6 0.2 0.3 -0.3 0.2
Overall health rating 0.1 0.3 1.1 0.6 0.7 0.3 -0.6 0.2 -0.1 0.7 -0.0 0.5 1.1 0.5 -0.3 -0.7 -0.5 0.3
Chest pain or discomfort 5.6 8.1 16.7 3.5 3.5 3.1 0.3 2.1 2.0 4.1 1.9 3.3 3.1 3.4 2.1 0.9 -3.3 3.3
Had major operations 1.0 1.1 3.2 -0.8 -0.9 -0.8 -1.8 -0.2 -0.7 -0.8 -1.2 -1.4 -1.1 -1.0 -1.7 0.6 0.9 -1.0
Age at last live birth 0.2 0.3 2.3 -0.2 0.8 -0.5 -0.6 0.1 1.5 0.3 -0.4 -0.0 -0.8 -0.2 -0.5 0.3 0.2 -0.2
Family relationship satisfaction 0.4 0.5 3.3 0.6 0.6 0.6 -0.0 1.8 -0.3 0.7 0.4 0.8 0.3 0.6 0.4 0.4 -0.7 0.6
Leg pain on walking 0.5 0.6 2.0 0.6 -0.2 0.7 -0.8 -0.3 1.2 0.8 -1.1 0.1 -0.0 0.5 -1.0 1.4 -0.4 0.0
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.7 2.8 0.5 1.7 0.4 -1.1 0.3 -0.2 1.2 -0.1 0.7 1.2 0.7 0.9 0.3 -0.5 0.7
Commuting to job workplace: Car/motor vehicle 2.4 2.8 5.8 -1.6 -0.8 -1.9 -2.4 -0.1 -1.8 -1.1 -2.4 -1.6 -2.0 -1.7 -1.4 -0.1 1.8 -2.0
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 2.9 -0.0 -0.2 -0.2 0.9 -1.7 -0.1 -0.5 0.5 -0.1 0.2 0.1 0.6 0.4 -0.0 -0.1
Medication: Aspirin 0.5 0.6 3.6 -0.5 0.7 -0.7 -1.9 -0.4 -1.4 0.1 -0.6 -0.6 0.8 -0.5 0.4 0.1 0.5 -0.4
Supplements: Vitamin C 1.0 1.2 6.5 0.9 -0.0 1.1 0.1 0.4 2.0 0.6 1.0 0.6 0.6 0.8 -0.9 2.5 -0.9 0.9
Knee pain experienced in last month 1.0 1.6 4.7 -1.0 -0.8 -1.4 -1.2 -0.7 -1.4 -0.9 -2.2 -1.1 -0.6 -1.1 -1.6 -1.5 1.3 -1.4
Hypertension (Self-reported) 0.1 0.3 0.8 -0.3 0.2 -0.7 -0.5 -0.5 -0.4 -0.9 -0.3 -0.4 0.9 -0.5 0.7 0.1 0.4 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.2 2.6 7.0 1.7 0.5 1.4 2.6 2.3 1.9 0.8 2.1 1.2 1.7 1.8 -0.4 0.5 -1.7 1.7
Illnesses of father: Heart disease 1.4 1.9 4.0 1.6 1.4 1.6 1.4 0.4 1.6 1.4 2.0 1.5 0.5 1.7 0.7 0.6 -1.5 1.7
Illnesses of siblings: Diabetes 0.3 0.3 1.3 -0.5 -0.1 -0.6 -1.1 0.6 -0.9 -0.3 -0.8 -0.3 -0.4 -0.5 0.5 0.5 0.3 -0.2
Smoking status: Previous 4.9 7.3 10.5 3.2 2.8 3.2 0.9 2.6 2.6 3.2 2.5 2.9 2.7 3.2 1.6 1.5 -3.2 3.0
Forced expiratory volume in 1-second (FEV1), predicted 1.7 3.5 7.1 2.2 1.7 1.9 1.2 1.6 1.7 2.7 1.4 2.3 1.7 2.4 0.6 1.3 -2.2 2.0
Whole body fat-free mass 0.4 2.0 7.5 -0.4 -2.7 -0.6 1.9 -0.3 0.5 -1.6 -0.9 -0.4 -1.6 -0.3 -2.5 -2.4 0.1 -0.7
Leg fat-free mass (right) 0.5 2.6 9.0 -0.8 -3.0 -1.0 1.7 -0.1 0.2 -2.1 -1.3 -0.7 -2.2 -0.7 -2.7 -2.2 0.5 -1.1
Arm fat percentage (left) 3.3 13.3 23.9 -3.9 -4.2 -4.0 -1.4 -1.0 -3.6 -4.9 -4.1 -3.9 -3.8 -4.1 -2.6 -3.2 3.7 -4.0
Average weekly red wine intake 0.9 1.3 2.7 1.3 1.2 1.4 0.1 -0.3 1.0 1.2 1.6 1.1 1.0 1.1 1.4 0.3 -1.3 1.5
Handedness (chirality/laterality): Left-handed 2.3 2.7 7.8 1.5 2.8 1.8 -0.6 0.7 1.4 2.4 1.2 1.9 2.1 1.4 1.0 0.0 -1.5 1.8
Mood swings 2.8 5.1 7.5 2.5 1.9 2.3 2.7 2.2 2.7 2.3 2.7 2.1 2.1 2.5 1.3 -0.2 -2.4 2.6
Loneliness, isolation 2.3 3.2 6.7 -1.7 -2.4 -1.6 -0.2 -0.3 -1.7 -1.9 -2.6 -1.9 -1.9 -1.8 -1.7 -1.9 1.6 -2.0
Long-standing illness, disability or infirmity 0.2 0.4 2.4 -0.1 0.1 -0.4 -0.6 0.5 -0.6 -0.1 -1.1 0.1 0.3 -0.3 -0.5 -1.5 0.1 -0.3
Ever had bowel cancer screening 0.1 0.2 1.0 0.1 0.1 0.6 0.0 -0.1 -0.6 -0.1 0.2 0.0 0.1 -0.2 1.0 -0.1 -0.1 0.6
Diabetes diagnosed by doctor 1.1 1.8 4.9 -1.3 -1.2 -1.5 -1.0 -1.9 0.1 -1.1 -2.2 -1.4 -1.3 -1.1 -1.1 0.1 1.4 -1.5
Ever had stillbirth, spontaneous miscarriage or termination 1.2 1.3 3.7 -1.1 -0.3 -1.0 -1.6 -1.6 -1.0 -0.6 -1.9 -0.6 -1.0 -0.9 -1.4 0.9 0.9 -1.0
Friendships satisfaction 0.3 0.4 2.1 0.2 -1.1 0.5 1.5 0.9 0.5 -0.6 0.2 0.2 -0.3 0.4 0.5 0.0 -0.4 0.3
Qualifications: nursing, teaching 0.8 1.2 3.5 0.5 1.8 0.4 0.4 1.0 0.4 0.7 1.2 0.6 1.4 0.6 1.9 -1.8 -0.6 0.9
Commuting to job workplace: Walk 1.6 1.7 3.8 1.4 2.0 1.0 -1.0 0.4 1.2 1.7 0.5 1.6 1.8 1.6 0.3 0.2 -1.5 1.4
Eye problems/disorders: Cataract 0.9 1.1 3.8 -0.9 -1.7 -1.0 -0.0 -0.5 -1.0 -1.9 -0.9 -0.9 -0.7 -0.9 -1.2 -0.9 0.8 -0.9
Mouth/teeth dental problems: Mouth ulcers 0.2 0.4 1.6 -0.3 0.4 0.1 -1.2 -0.1 -1.1 0.3 -0.2 -0.3 -0.3 -0.4 0.6 1.3 0.3 -0.0
Medication for cholesterol 2.1 3.1 5.6 1.9 2.1 2.0 0.4 1.5 1.7 2.4 1.8 1.8 1.5 2.0 2.1 0.4 -1.8 1.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.4 1.5 -0.8 0.2 -0.8 0.1 -0.5 -0.2 -0.9 -0.1 -1.2 -0.8 -0.7 -0.3 -0.0 0.9 -0.6
Back pain experienced in last month 1.9 2.8 5.3 -2.0 -0.7 -2.3 -1.0 -2.2 0.6 -1.7 -2.0 -2.1 -1.6 -1.7 -0.5 0.2 2.1 -2.0
Mineral and other dietary supplements 0.2 0.2 1.7 -0.3 0.3 -0.5 1.3 0.2 -0.6 -0.6 0.8 0.1 -0.2 -0.2 -0.1 -0.0 0.2 0.1
Breast cancer (self-reported) 0.3 0.3 2.2 0.2 0.3 -0.1 1.5 -1.1 0.6 -0.3 0.3 0.6 0.5 0.3 -0.3 0.3 -0.4 0.3
Asthma (self-reported) 1.7 3.4 6.7 2.3 1.9 1.9 0.3 1.9 -0.0 2.6 1.7 2.1 2.5 2.3 -0.2 -0.5 -2.1 2.1
Osteoporosis (self-reported) 3.1 3.9 6.7 2.2 2.2 2.2 1.3 0.2 1.6 2.2 2.6 1.9 1.7 2.1 1.2 2.1 -2.2 2.5
Osteoarthritis (self-reported) 5.8 7.5 12.1 -2.8 -3.5 -2.7 -1.4 -0.6 -3.4 -2.9 -2.9 -2.7 -2.6 -2.8 -1.8 -3.5 2.7 -3.2
Medication: Aspirin 0.6 0.7 3.0 -0.7 0.3 -1.0 -1.7 -0.5 -1.7 -0.4 -0.8 -0.9 0.6 -0.7 0.0 0.2 0.8 -0.7
Medication: Gliclazide 0.5 0.6 2.2 -0.4 -0.9 -1.0 -1.2 -0.2 -0.6 -0.5 -1.5 -0.1 -0.3 -0.1 -1.0 0.7 0.5 -0.8
Illnesses of father: None of the above (group 1) 4.1 5.1 7.7 -2.8 -1.6 -2.7 -1.3 -0.9 -2.7 -2.5 -2.3 -2.6 -2.1 -2.8 -0.2 -2.2 2.7 -2.7
Smoking status: Current 0.2 0.4 1.0 0.6 1.0 0.7 -0.1 0.6 0.4 0.9 0.3 0.5 -0.4 0.6 0.9 0.2 -0.4 0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.8 1.8 1.1 0.6 0.9 -0.5 0.8 -0.4 0.8 0.4 1.4 1.0 1.0 -0.0 1.1 -1.3 1.0
Whole body water mass 0.4 2.1 7.4 -0.4 -2.7 -0.6 1.9 -0.2 0.3 -1.6 -0.9 -0.4 -1.7 -0.4 -2.5 -2.5 0.1 -0.7
Leg predicted mass (right) 0.5 2.6 8.8 -0.8 -3.0 -1.0 1.7 -0.1 0.2 -2.1 -1.3 -0.7 -2.2 -0.7 -2.7 -2.3 0.5 -1.1
Arm fat mass (left) 3.1 12.9 23.3 -3.7 -4.5 -3.8 -0.9 -1.5 -2.9 -4.8 -4.1 -3.7 -4.0 -3.9 -3.2 -3.4 3.5 -3.8
Number of self-reported non-cancer illnesses 0.7 1.2 5.9 1.3 0.8 1.1 -0.4 1.1 0.2 0.8 0.4 1.2 2.4 1.0 0.6 -0.9 -1.2 1.2
Average weekly champagne plus white wine intake 0.1 0.1 1.3 -0.2 -0.1 0.1 0.3 0.2 0.5 -0.3 -0.2 -0.2 -0.3 -0.3 -0.2 -1.1 0.1 -0.0
Miserableness 0.2 0.3 1.0 0.5 0.8 0.6 0.1 0.7 1.0 0.8 0.3 0.4 0.5 0.6 0.2 -0.3 -0.5 0.5
Guilty feelings 1.4 2.2 4.1 1.8 1.3 1.6 0.5 0.8 0.2 1.2 1.7 2.0 1.4 1.8 1.0 -1.1 -2.0 2.0
Wears glasses or contact lenses 0.8 0.9 3.6 0.7 1.4 0.5 -1.1 1.2 -0.1 0.8 -0.2 0.5 1.1 0.7 1.9 -1.2 -0.7 0.7
Ever taken oral contraceptive pill 0.8 0.9 5.9 0.8 0.4 0.9 0.7 0.0 2.4 0.6 1.1 0.1 0.1 0.9 -0.9 -0.3 -0.9 0.9
Hearing aid user 2.0 2.3 3.9 1.6 1.5 0.7 1.2 2.0 1.1 1.6 1.6 1.7 2.0 2.0 1.0 0.7 -1.6 1.6
Mother’s age at death 1.3 1.6 5.0 -1.3 -0.8 -1.0 0.2 -2.2 -0.8 -1.3 -0.8 -1.5 -1.9 -1.4 -1.3 0.2 1.3 -0.9
Financial situation satisfaction 1.0 1.3 3.1 1.1 0.0 1.7 1.6 1.0 1.8 0.4 1.3 0.6 -0.1 0.9 0.3 1.5 -1.1 1.2
Tinnitus: Yes, now most or all of the time 0.6 0.6 4.1 0.7 -1.1 0.7 1.0 2.0 -0.1 0.3 0.5 0.7 0.7 0.6 0.5 -0.2 -0.7 0.3
Commuting to job workplace: Public transport 0.9 1.1 2.8 1.0 0.7 1.3 0.8 0.5 1.4 0.7 1.7 0.9 1.6 0.8 0.6 -0.6 -1.0 1.3
Eye problems/disorders: Glaucoma 2.8 3.3 7.0 2.1 0.9 1.9 2.2 2.6 0.8 1.2 2.2 2.0 2.0 2.0 1.2 0.9 -2.0 2.2
Medication: Blood pressure 0.6 1.2 2.8 -1.1 -1.5 -1.3 -0.1 -1.7 -0.9 -1.6 -1.2 -1.1 -0.5 -1.2 -0.6 -0.2 1.1 -1.1
Pain type(s) experienced in last month: Hip pain 2.1 2.6 3.8 -1.7 -1.6 -1.4 -1.4 -1.7 -1.9 -1.5 -1.8 -1.9 -1.6 -1.6 -0.4 -1.5 1.7 -1.8
Supplements: Fish oil (including cod liver oil) 0.2 0.3 1.0 -0.1 -0.2 0.3 -1.0 -0.7 0.6 0.0 -0.6 -0.5 -0.2 -0.2 0.6 -0.9 0.1 -0.2
High cholesterol (Self-reported) 1.3 2.2 4.8 -1.5 -1.8 -1.4 -1.3 -0.3 -2.2 -1.5 -1.7 -1.7 -0.9 -1.8 -1.0 -1.1 1.5 -1.7
Medication: Bendroflumethiazide 1.4 2.2 5.5 -1.6 -2.3 -1.5 0.4 -0.4 -1.5 -2.3 -0.9 -1.5 -1.0 -1.6 -1.8 -0.1 1.5 -1.6
Medication: Paracetamol 0.3 0.5 2.4 -0.4 1.5 -0.6 -1.2 1.0 -0.2 0.5 -0.7 -0.4 0.0 -0.4 0.6 0.1 0.6 -0.1
Medication: Lisinopril 2.9 3.7 7.2 -2.4 -0.9 -2.7 -0.7 -2.4 -0.3 -2.2 -1.9 -2.3 -1.3 -2.2 -1.0 -1.4 2.7 -2.3
Medication: Atorvastatin 0.4 0.5 1.9 0.1 0.2 0.3 -1.4 0.1 -0.0 0.6 -1.0 0.5 1.2 -0.0 1.4 0.0 -0.0 -0.1
Illnesses of father: High blood pressure 1.7 2.1 5.1 1.7 0.3 1.6 1.1 0.1 1.8 1.0 2.2 1.2 1.4 1.6 -0.4 2.3 -1.7 1.4
Alcohol drinker status: Never 2.1 2.5 8.0 1.4 2.8 1.0 0.4 0.7 1.3 2.0 0.9 1.6 2.2 1.5 1.6 -1.3 -1.4 1.6
Ever smoked 5.1 8.9 15.5 3.6 3.6 3.6 1.0 2.2 2.6 3.9 2.4 3.3 2.8 3.7 1.9 1.2 -3.5 3.4
Basal metabolic rate 0.5 2.8 10.0 -0.8 -3.2 -1.0 1.7 -0.3 0.2 -2.1 -1.3 -0.8 -2.0 -0.7 -2.8 -2.6 0.5 -1.1
Leg fat percentage (left) 3.6 13.0 20.8 -3.7 -4.0 -3.5 -1.9 -1.8 -3.9 -4.6 -4.2 -3.8 -3.7 -4.1 -2.5 -3.7 3.6 -3.9
Arm fat-free mass (left) 0.7 3.5 10.7 -1.2 -3.3 -1.3 1.3 -1.0 -0.2 -2.3 -1.8 -1.3 -2.4 -1.2 -2.8 -2.7 1.0 -1.5
Number of operations (self-reported) 0.3 0.5 1.5 0.8 0.4 0.9 -0.6 0.1 -0.3 1.1 0.1 0.4 0.4 0.4 1.2 -1.1 -0.8 0.7
Average weekly beer plus cider intake 5.2 7.6 19.3 -2.8 -4.4 -2.6 -0.5 -1.0 -0.7 -3.5 -3.1 -3.2 -3.1 -2.8 -3.0 0.3 2.8 -3.3
Irritability 4.7 8.0 12.7 3.3 2.9 3.2 2.1 1.7 3.3 3.6 3.1 2.7 2.6 3.1 2.0 -0.5 -3.2 3.3
Risk taking 0.3 0.5 1.9 -0.1 -1.3 -0.0 0.2 0.4 1.2 -0.0 -0.8 -0.2 -0.2 -0.1 -1.4 1.0 0.0 -0.5
Ever had prostate specific antigen (PSA) test 1.2 1.4 9.2 0.5 1.4 1.1 -0.5 1.4 -1.4 0.7 0.9 0.1 0.9 0.3 3.0 1.0 -0.6 0.9
Fractured/broken bones in last 5 years 1.1 1.4 5.1 1.2 1.6 1.2 0.9 2.3 0.2 1.4 0.9 1.2 0.8 0.9 1.3 0.1 -0.9 1.2
Age started oral contraceptive pill 0.7 0.9 2.1 0.9 1.3 0.9 0.8 0.4 0.2 1.2 1.0 0.8 1.0 0.8 1.4 -1.2 -0.7 0.8
Diastolic blood pressure, automated reading 0.8 2.6 6.1 1.5 1.6 1.1 2.1 1.9 0.0 0.2 2.5 1.8 1.7 1.5 2.0 0.8 -1.5 2.0
Ever depressed for a whole week 0.4 0.5 1.7 0.4 -0.0 0.5 1.1 1.1 0.3 0.3 0.4 0.4 -0.0 0.5 1.2 1.3 -0.6 0.5
Unable to work because of sickness or disability 0.1 0.1 1.1 0.1 -0.1 -0.1 0.1 1.1 -0.5 -0.0 0.3 -0.1 0.3 0.1 0.7 0.1 0.0 -0.2
Commuting to job workplace: Cycle 2.2 2.7 7.3 1.6 2.0 1.6 0.5 1.5 0.7 2.1 1.2 1.8 2.0 1.6 2.7 0.2 -1.6 1.5
Myopia 0.9 1.3 9.5 -0.7 0.0 -0.4 -1.0 -0.3 -2.3 -0.2 -0.5 -0.0 0.1 -0.7 1.0 -3.1 0.6 -0.5
Vascular/heart problems diagnosed by doctor 0.1 0.3 1.5 -0.2 -0.6 0.1 0.3 0.4 0.3 0.4 -0.1 -0.1 -1.2 -0.0 -1.1 -0.5 0.1 -0.4
Cholesterol lowering medication 0.8 1.2 2.2 -1.1 -1.3 -1.1 -0.5 -0.3 -1.5 -1.1 -1.3 -1.1 -0.5 -1.3 -0.4 -1.5 1.0 -1.3
Medication: Omeprazole (e.g. Zanprol) 1.2 1.5 6.5 -0.9 -1.3 -0.8 0.4 1.2 -2.5 -1.6 -0.9 -1.1 -0.3 -1.3 -1.1 -1.2 1.0 -1.0
Pain experienced in last month 1.1 1.8 4.3 1.3 0.8 1.3 1.4 2.0 -0.1 1.0 2.1 1.8 1.2 1.1 0.9 1.0 -1.5 1.6
Supplements: Calcium 1.9 2.1 3.7 1.8 1.1 1.5 1.0 1.6 1.3 1.8 1.5 1.7 1.3 1.9 0.8 0.5 -1.6 1.6
Basal cell carcinoma (self-reported) 0.4 0.5 3.3 -0.1 -0.6 0.1 1.8 1.2 0.1 -0.3 0.4 -0.0 -0.1 0.0 1.0 -0.9 0.1 -0.1
Heart attack/myocardial infarction (self-reported) 0.1 0.2 1.4 0.3 -0.3 0.0 1.2 0.1 0.5 -0.2 -0.1 0.0 0.1 0.4 0.4 0.5 -0.4 0.3
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 2.8 0.7 1.2 0.5 0.8 0.5 1.7 1.1 0.3 0.4 0.5 0.5 0.9 0.5 -0.5 0.5
Heart disease (siblings) 0.5 0.6 3.9 0.4 -0.2 0.7 1.6 0.2 0.3 -0.1 1.2 -0.1 -0.5 0.1 2.0 0.4 -0.4 0.6
Alcohol drinker status: Previous 3.1 3.5 10.9 2.0 3.3 2.2 -1.3 -0.9 1.3 2.7 1.0 1.8 2.4 1.8 0.1 -0.5 -1.8 2.2
Pack years of smoking 0.9 1.3 7.3 0.6 2.7 0.5 -2.0 -0.3 0.3 1.7 -0.1 0.4 1.1 0.4 1.3 0.1 -0.5 0.7
Impedance of whole body 1.1 5.8 15.2 2.3 2.7 2.5 -0.5 1.8 2.4 2.9 2.5 2.1 2.0 2.4 2.2 3.9 -2.0 2.2
Leg fat mass (left) 3.3 13.0 22.2 -3.6 -4.6 -3.5 -1.1 -1.5 -3.1 -4.7 -4.2 -3.7 -4.1 -3.9 -3.1 -3.7 3.4 -3.8
Arm predicted mass (left) 0.8 4.0 11.2 -1.4 -3.3 -1.6 1.0 -1.2 -0.4 -2.4 -2.0 -1.5 -2.4 -1.4 -3.0 -3.0 1.2 -1.7