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chr20:61,522,825-62,912,463

Best TWAS P=2.55e-13 · Best GWAS P=1.85e-13 conditioned to 0.0186

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ARFRP1	0.07	0.07	lasso	3	0.06	5.3e-08	-5.8	6.4	1.8e-10	-0.67	0.65	0.35	FALSE
2	CommonMind	Brain Pre-frontal Cortex	STMN3	0.07	0.02	lasso	4	0.05	2.8e-06	-6.7	-5.7	1.1e-08	0.53	0.07	0.92	FALSE
3	GTEx	Brain Cerebellar Hemisphere	STMN3	0.39	0.08	lasso	5	0.22	2.1e-06	-6.7	-5.6	2.6e-08	0.37	0.04	0.89	FALSE
4	GTEx	Brain Cerebellum	STMN3	0.33	0.12	lasso	10	0.20	1.8e-06	-6.3	-7.1	1.5e-12	0.59	0.06	0.92	FALSE
5	GTEx	Brain Cortex	STMN3	0.25	0.09	lasso	7	0.11	6.8e-04	-6.5	-7.3	2.6e-13	0.82	0.02	0.95	TRUE
6	GTEx	Breast Mammary Tissue (Female)	GMEB2	0.36	0.06	lasso	4	0.05	1.2e-02	-6.9	-6.5	6.0e-11	0.58	0.04	0.78	FALSE
7	GTEx	Cells Transformed fibroblasts	CTD-3184A7.4	0.09	0.00	enet	28	0.00	1.4e-01	-3.4	-5.7	1.6e-08	0.44	0.04	0.68	FALSE
8	GTEx	Testis	RTEL1	0.19	0.06	lasso	5	0.14	8.0e-07	-6.5	-6.1	1.1e-09	0.61	0.04	0.92	FALSE
9	GTEx	Thyroid	SLC2A4RG	0.12	0.06	lasso	5	0.04	2.4e-04	-6.3	6.6	4.2e-11	-0.76	0.02	0.98	FALSE
10	GTEx	Whole Blood	STMN3	0.10	0.00	lasso	3	0.00	1.2e-01	-5.7	6.8	7.9e-12	-0.50	0.06	0.44	FALSE
11	YFS	Blood	LIME1	0.12	0.19	enet	15	0.19	5.3e-59	-5.7	-5.8	8.4e-09	0.59	0.98	0.02	FALSE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	STMN3	0.02	0.02	blup	43	0.02	1.7e-03	-6.6	-6.4	1.2e-10	0.58	0.01	0.90	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TNFRSF6B	0.03	0.01	blup	44	0.02	7.1e-04	-6.3	-6.7	2.0e-11	0.74	0.03	0.90	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC2A4RG	0.03	0.01	blup	48	0.02	2.4e-03	-6.3	6.4	1.1e-10	-0.68	0.06	0.45	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIME1	0.02	0.03	blup	47	0.02	6.2e-03	-6.5	-7.0	3.0e-12	0.77	0.04	0.47	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZGPAT	0.05	0.04	blup	60	0.05	7.2e-07	-6.4	6.1	8.7e-10	-0.72	0.08	0.91	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	TNFRSF6B	0.02	0.01	enet	7	0.01	6.9e-03	-6.4	-6.6	5.4e-11	0.72	0.08	0.43	FALSE
18	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RTEL1	0.05	0.04	blup	56	0.03	4.2e-03	-4.9	-6.5	5.9e-11	0.64	0.03	0.42	FALSE
19	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	STMN3	0.07	0.01	blup	41	0.05	4.2e-04	-6.7	-6.4	1.9e-10	0.54	0.01	0.95	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARFRP1	0.03	0.02	lasso	2	0.02	1.2e-03	-5.8	5.8	5.6e-09	-0.56	0.18	0.20	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	LIME1	0.04	0.05	blup	47	0.05	9.0e-06	-5.6	-6.1	1.4e-09	0.69	0.41	0.56	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC2A4RG	0.05	0.01	blup	48	0.02	2.0e-03	-5.9	5.9	3.0e-09	-0.56	0.06	0.69	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZGPAT	0.05	0.06	lasso	3	0.06	5.5e-07	-6.7	6.8	1.4e-11	-0.72	0.30	0.70	FALSE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LIME1	0.10	0.02	blup	47	0.04	1.5e-02	-5.9	-6.3	4.1e-10	0.72	0.02	0.25	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	LIME1	0.05	0.03	blup	47	0.04	3.9e-05	-6.4	-6.8	1.4e-11	0.82	0.03	0.96	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	ZGPAT	0.05	0.04	blup	60	0.03	2.3e-04	-6.4	6.3	2.2e-10	-0.75	0.09	0.89	FALSE