Best TWAS P=8.8e-10 · Best GWAS P=1.96e-07 conditioned to 0.157
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | PCNT | 0.22 | 0.11 | bslmm | 431 | 0.16 | 5.5e-49 | 3.3 | 5.1 | 2.8e-07 | -0.72 | 0.61 | 0.16 | FALSE |
| 2 | The Cancer Genome Atlas | Glioblastoma Multiforme | MCM3APAS | 0.26 | 0.03 | blup | 68 | 0.09 | 9.1e-04 | 3.3 | 5.2 | 1.6e-07 | -0.75 | 0.00 | 0.02 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LSS | 0.10 | 0.08 | enet | 12 | 0.10 | 7.4e-12 | 3.5 | 5.4 | 7.4e-08 | -0.71 | 0.02 | 0.57 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MCM3APAS | 0.09 | 0.01 | blup | 73 | 0.05 | 5.1e-06 | -3.7 | 6.1 | 8.8e-10 | -0.68 | 0.00 | 0.23 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | MCM3AP | 0.15 | 0.10 | blup | 73 | 0.12 | 1.2e-11 | -3.7 | -5.1 | 3.1e-07 | 0.77 | 0.01 | 0.77 | FALSE |