[Hub]/) : Traits : Bipolar Disorder (2018) : ← →

chr19:18,674,057-20,432,930

Best TWAS P=1.17e-08 · Best GWAS P=7.21e-09 conditioned to 0.104

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HAPLN4 0.07 0.10 lasso 6 0.10 5.3e-12 5.5 5.2 1.7e-07 0.97 0.02 0.97 FALSE
2 GTEx Colon Transverse YJEFN3 0.09 0.09 lasso 3 0.07 4.3e-04 5.2 -5.6 1.9e-08 -0.88 0.03 0.92 FALSE
3 GTEx Spleen LPAR2 0.27 0.06 lasso 6 0.04 2.7e-02 3.9 -5.4 5.9e-08 -0.70 0.04 0.69 FALSE
4 GTEx Thyroid YJEFN3 0.05 0.02 lasso 3 0.02 1.2e-02 5.6 -5.3 1.2e-07 -0.82 0.05 0.81 FALSE
5 GTEx Whole Blood LPAR2 0.10 0.07 lasso 5 0.07 8.0e-07 4.6 -5.5 4.0e-08 -0.78 0.19 0.81 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma CILP2 0.02 0.02 blup 30 0.02 1.6e-04 5.3 5.2 2.0e-07 0.91 0.01 0.96 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma TSSK6 0.07 0.02 blup 32 0.04 2.9e-03 5.2 5.3 9.8e-08 0.83 0.01 0.83 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma YJEFN3 0.03 0.03 blup 32 0.02 3.0e-03 5.2 -5.6 1.8e-08 -0.88 0.01 0.92 FALSE
9 The Cancer Genome Atlas Prostate Adenocarcinoma YJEFN3 0.04 0.05 lasso 2 0.05 4.3e-06 5.4 -5.3 9.0e-08 -0.93 0.01 0.99 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma YJEFN3 0.08 0.06 blup 33 0.08 7.1e-08 5.4 -5.7 1.2e-08 -0.88 0.01 0.99 TRUE