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chr5:139,232,299-141,087,689

Best TWAS P=7.22e-09 · Best GWAS P=2.01e-07 conditioned to 0.456

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NDUFA2	0.02	0.01	bslmm	343	0.01	7.8e-03	5.1	-5.6	1.7e-08	-0.85	0.08	0.70	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PCDHA7	0.13	0.14	lasso	8	0.14	5.1e-17	5.1	5.1	2.8e-07	0.92	0.07	0.92	FALSE
3	CommonMind	Brain Pre-frontal Cortex	ZMAT2	0.06	0.10	blup	360	0.09	1.4e-11	5.1	5.1	2.8e-07	0.88	0.07	0.93	FALSE
4	GTEx	Artery Tibial	IK	0.06	0.04	enet	13	0.05	1.3e-04	4.9	5.2	2.3e-07	0.90	0.07	0.93	FALSE
5	GTEx	Brain Cerebellar Hemisphere	WDR55	0.11	0.07	enet	10	-0.01	6.6e-01	4.7	5.2	2.0e-07	0.85	0.07	0.66	FALSE
6	GTEx	Cells Transformed fibroblasts	IK	0.07	0.04	lasso	4	0.02	1.0e-02	5.2	5.2	2.1e-07	0.93	0.07	0.92	FALSE
7	GTEx	Cells Transformed fibroblasts	ZMAT2	0.04	0.02	lasso	4	0.02	2.4e-02	5.2	5.3	1.3e-07	0.90	0.06	0.86	FALSE
8	GTEx	Esophagus Mucosa	TMCO6	0.04	0.02	lasso	4	0.01	6.1e-02	4.3	5.3	1.4e-07	0.76	0.10	0.68	FALSE
9	GTEx	Esophagus Muscularis	WDR55	0.05	0.01	lasso	4	0.03	6.6e-03	5.0	5.4	6.2e-08	0.90	0.07	0.74	FALSE
10	GTEx	Nerve Tibial	IK	0.08	0.08	lasso	8	0.06	8.3e-05	5.2	5.2	1.8e-07	0.99	0.06	0.94	FALSE
11	GTEx	Skin Sun Exposed Lower leg	SRA1	0.05	0.04	lasso	3	0.06	1.0e-05	4.5	5.4	7.8e-08	0.78	0.22	0.71	FALSE
12	GTEx	Vagina	IK	0.27	0.09	enet	29	0.15	2.4e-04	4.9	5.8	7.2e-09	0.83	0.09	0.87	TRUE
13	ROSMAP	Brain Pre-frontal Cortex	ZMAT2	0.03	0.02	bslmm	185	0.02	6.5e-04	4.7	5.2	2.5e-07	0.86	0.05	0.94	FALSE
14	YFS	Blood	APBB3	0.01	0.00	bslmm	318	0.00	2.7e-02	3.5	-5.5	4.3e-08	-0.74	0.15	0.28	FALSE
15	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	NDUFA2	0.07	0.04	blup	41	0.03	1.8e-03	5.0	-5.2	2.5e-07	-0.91	0.01	0.97	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	PCDHA4	0.01	0.02	lasso	1	0.01	4.9e-04	5.2	5.2	2.2e-07	0.91	0.01	0.94	FALSE
17	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	WDR55	0.02	0.02	lasso	2	0.02	2.3e-03	5.2	5.1	2.8e-07	1.00	0.02	0.93	FALSE
18	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NDUFA2	0.10	0.04	blup	43	0.06	1.4e-03	5.0	-5.1	3.0e-07	-0.92	0.02	0.91	FALSE
19	The Cancer Genome Atlas	Stomach Adenocarcinoma	PCDHA4	0.03	0.01	blup	31	0.02	2.0e-02	4.9	5.4	5.7e-08	0.75	0.01	0.70	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	NDUFA2	0.03	0.01	blup	41	0.03	8.3e-04	5.0	-5.1	2.9e-07	-0.94	0.02	0.87	FALSE