TWAS hub

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0270	0.0140	8.9e-04	0.021	0.024	0.017	0.024	0.033	1.3e-03	5.7e-04	3.3e-03	6.1e-04	6.0e-05
2	GTEx	Adipose Subcutaneous	0.1610	0.0550	4.8e-08	0.074	NA	0.049	NA	0.069	1.1e-06	NA	6.9e-05	NA	2.7e-06
3	GTEx	Artery Aorta	0.0480	0.0260	2.9e-03	0.020	NA	-0.004	NA	0.010	2.7e-02	NA	7.1e-01	NA	8.4e-02
4	GTEx	Artery Tibial	0.0591	0.0277	7.7e-05	0.035	NA	0.047	NA	0.045	8.6e-04	NA	1.3e-04	NA	1.9e-04
5	GTEx	Breast Mammary Tissue	0.0680	0.0310	4.7e-04	0.061	NA	0.050	NA	0.064	4.6e-04	NA	1.4e-03	NA	3.5e-04
6	GTEx	Breast Mammary Tissue (Male)	0.1039	0.0951	1.1e-01	-0.002	NA	0.000	NA	-0.013	3.7e-01	NA	3.3e-01	NA	8.6e-01
7	GTEx	Cells Transformed fibroblasts	0.0670	0.0320	1.5e-04	0.038	NA	0.017	NA	0.021	7.5e-04	NA	1.7e-02	NA	1.0e-02
8	GTEx	Colon Transverse	0.1210	0.0640	6.7e-04	0.010	NA	0.032	NA	-0.005	1.1e-01	NA	1.2e-02	NA	6.2e-01
9	GTEx	Esophagus Muscularis	0.0380	0.0220	8.3e-03	0.054	NA	0.014	NA	0.012	3.3e-04	NA	4.7e-02	NA	5.8e-02
10	GTEx	Nerve Tibial	0.0781	0.0378	8.1e-05	0.076	NA	0.050	NA	0.056	4.4e-06	NA	1.8e-04	NA	8.3e-05
11	GTEx	Ovary	0.2780	0.1150	4.3e-03	-0.007	NA	0.060	NA	-0.011	5.2e-01	NA	1.4e-02	NA	7.8e-01
12	GTEx	Skin Not Sun Exposed Suprapubic	0.0770	0.0400	1.6e-03	0.054	NA	0.038	NA	0.040	6.6e-04	NA	3.5e-03	NA	3.0e-03
13	GTEx	Skin Sun Exposed Lower leg	0.2010	0.0670	6.7e-07	0.073	NA	0.046	NA	0.001	1.3e-06	NA	1.1e-04	NA	2.4e-01
14	GTEx	Stomach	0.0650	0.0390	9.3e-03	0.027	NA	0.009	NA	0.019	1.8e-02	NA	1.2e-01	NA	3.9e-02
15	GTEx	Vagina	0.2740	0.0970	7.7e-06	0.091	NA	0.153	NA	0.051	4.2e-03	NA	2.4e-04	NA	2.7e-02
16	METSIM	Adipose	0.1293	0.0416	6.8e-11	0.094	0.073	0.121	0.105	0.098	6.5e-14	3.9e-11	1.2e-17	1.7e-15	1.7e-14
17	YFS	Blood	0.0701	0.0243	5.6e-17	0.054	0.056	0.052	0.055	0.051	4.4e-17	7.1e-18	1.2e-16	1.5e-17	2.2e-16
18	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0710	0.0460	6.1e-03	0.048	0.019	0.004	NA	0.035	9.5e-04	2.8e-02	1.8e-01	NA	4.4e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	7	8	9	10	11	12	13	14	15	16	17	18
Schizophrenia (2018)	8.8	18.3	32.0	4.3	5.0	4.0	5.3	4.9	4.9	4.0	4.1	5.0	2.0	4.6	3.6	2.8	5.7	5.5	4.8	-2.4
Ever unenthusiastic/disinterested for a whole week	8.8	10.8	19.5	-2.9	-3.7	-2.6	-3.7	-4.3	-4.4	-3.5	-3.5	-4.4	-3.1	-3.7	-2.3	-2.1	-3.6	-2.3	-3.3	2.6
Intelligence (Savage-Jansen 2018)	7.2	22.1	39.8	-4.6	-5.6	-3.9	-6.3	-6.3	-6.2	-4.5	-4.0	-5.9	-4.7	-5.6	-4.1	-2.3	-6.2	-4.1	-3.3	0.3
Bipolar Disorder or Schizophrenia	6.9	16.9	33.5	4.0	4.7	3.9	5.2	5.0	5.2	3.6	3.8	5.2	2.8	4.5	2.9	2.4	5.8	4.6	4.5	-1.2
Depression (Nagel 2018)	6.9	10.4	18.2	-2.8	-3.3	-2.3	-3.8	-4.1	-4.3	-3.3	-3.7	-3.7	-3.5	-3.6	-3.7	-1.3	-3.5	-2.8	-3.8	-0.7
Friendships satisfaction	6.4	7.9	16.3	-2.5	-2.9	-1.7	-3.7	-3.7	-4.0	-1.5	-3.6	-3.7	-2.3	-2.7	-3.0	-1.3	-2.8	-2.9	-3.3	0.2
Respiratory disease	6.0	13.4	25.4	-3.9	-4.4	-3.8	-4.4	-4.4	-5.0	-1.7	-3.9	-4.4	-3.9	-4.2	-4.3	-2.2	-3.6	-3.1	-3.2	1.1
Systolic Blood Pressure	5.9	29.6	51.3	5.4	6.2	3.1	6.6	7.2	7.0	3.8	5.5	7.1	3.7	6.4	5.6	3.3	6.5	5.2	6.8	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	5.0	16.0	22.3	-3.9	-4.6	-4.7	-4.5	-4.6	-4.5	-4.4	-4.1	-4.7	-3.8	-4.2	-3.4	-3.0	-4.7	-3.2	-4.0	3.0
Eye problems/disorders: None of the above	5.0	5.8	16.0	2.3	2.6	3.1	2.5	2.4	2.2	4.0	2.7	2.4	2.4	2.6	1.6	2.0	2.8	1.8	2.4	-1.3
Asthma (self-reported)	4.9	9.7	16.2	-3.2	-3.8	-3.8	-3.4	-3.6	-4.0	-1.9	-3.4	-3.5	-3.6	-3.6	-3.4	-1.7	-3.0	-3.3	-2.5	0.9
Schizophrenia (2014)	4.7	10.3	19.4	2.8	3.8	3.4	4.0	3.7	4.1	2.5	3.5	3.9	1.2	3.2	2.6	1.4	4.1	4.4	3.8	-1.1
Forced vital capacity (FVC), Best measure	4.7	17.3	26.5	-4.2	-4.9	-4.5	-4.7	-4.8	-4.6	-4.8	-4.0	-5.1	-4.4	-4.5	-3.2	-3.3	-5.1	-2.7	-3.9	2.9
Forced vital capacity (FVC)	4.6	17.5	25.3	-4.7	-4.9	-4.9	-4.5	-4.8	-4.3	-4.2	-3.9	-5.0	-4.3	-4.7	-3.7	-3.9	-4.7	-2.5	-3.8	3.7
Verbal and Numeric Reasoning (VNR)	4.4	10.5	21.8	-3.3	-3.7	-2.5	-4.3	-4.3	-4.3	-2.7	-2.8	-4.3	-3.5	-3.8	-2.2	-1.5	-4.7	-3.1	-1.8	-0.3
Alzheimer’s Disease (including proxy)	4.2	6.1	13.2	2.7	3.0	2.7	3.1	3.0	2.6	1.3	0.8	2.8	3.6	3.1	2.9	2.0	2.7	2.1	1.5	-0.8
Asthma	4.2	8.3	14.5	-3.1	-3.5	-3.7	-3.1	-3.4	-3.8	-1.6	-3.2	-3.2	-3.3	-3.4	-3.2	-1.5	-2.5	-3.0	-2.1	0.8
Medication: Bendroflumethiazide	4.2	6.4	11.1	3.1	2.9	2.4	3.0	3.1	2.8	2.6	2.5	2.7	1.8	3.3	1.4	2.3	2.7	1.6	2.6	-2.7
Number of operations (self-reported)	4.2	6.2	10.7	-3.3	-1.8	-2.1	-3.0	-2.6	-2.7	-2.5	-1.5	-2.9	-2.4	-2.8	-2.1	-2.6	-3.1	-0.7	-3.1	2.9
Medication: Simvastatin	4.1	6.0	11.7	3.1	3.1	2.6	3.0	2.8	2.1	2.4	1.8	2.6	2.4	3.1	3.4	2.5	2.6	1.0	2.0	-0.6
Mouth/teeth dental problems: Bleeding gums	4.1	5.4	10.4	2.5	2.1	3.0	2.6	2.4	2.5	2.6	2.6	2.3	3.2	2.5	1.4	2.0	2.7	1.3	1.7	-2.2
Had other major operations	3.9	4.8	13.7	-2.3	-1.8	-1.3	-2.6	-2.3	-2.9	-1.9	-2.0	-2.2	-1.4	-2.2	-1.3	-1.5	-3.0	-1.6	-3.7	2.5
Forced expiratory volume in 1-second (FEV1)	3.9	13.0	23.8	-3.9	-4.1	-4.9	-3.7	-3.9	-3.5	-3.9	-3.4	-4.1	-3.3	-3.9	-3.3	-3.5	-4.0	-2.4	-3.3	3.7
Length of working week for main job	3.8	4.2	11.0	-2.2	-2.2	-1.1	-1.9	-2.4	-2.2	-0.4	-3.3	-2.4	-2.6	-2.4	-1.4	-1.4	-1.6	-3.0	-1.6	1.5
Medication: Seretide 50 evohaler	3.8	4.4	9.4	-2.5	-2.7	-1.0	-2.3	-3.1	-2.6	-0.9	-3.0	-2.9	-2.3	-2.7	-1.5	-1.2	-1.9	-1.3	-1.6	1.3
Depressed Affect (Nagel 2018)	3.7	7.7	14.7	-2.1	-2.9	-1.2	-3.5	-3.5	-3.8	-3.3	-3.3	-3.4	-2.2	-2.7	-3.2	-0.5	-3.1	-2.4	-3.7	-0.9
Frequency of tiredness / lethargy in last 2 weeks	3.7	6.1	12.0	-1.9	-2.6	-2.8	-3.5	-2.7	-3.4	-3.3	-2.6	-2.9	-3.0	-2.2	-1.5	-0.5	-2.9	-1.0	-2.8	-0.9
Serious illness, injury or assault of a close relative in last 2 years	3.7	4.3	10.3	-3.2	-2.4	-1.9	-2.4	-2.3	-1.4	-1.8	-2.1	-2.6	-1.0	-2.9	-1.5	-3.2	-1.7	-1.0	-1.4	1.7
Bilateral oophorectomy (both ovaries removed)	3.6	4.2	8.8	-2.9	-1.9	-3.0	-2.1	-2.2	-1.5	-1.6	-1.4	-2.3	-2.6	-2.7	-1.4	-2.7	-1.8	-0.1	-1.1	2.5
Supplements: Glucosamine	3.5	4.5	10.7	2.3	2.3	3.3	2.4	2.0	2.1	1.5	2.6	2.1	2.2	2.2	2.0	1.5	2.1	2.0	0.9	-2.7
Sitting height	3.5	24.5	38.1	-6.0	-5.9	-4.0	-6.2	-5.9	-5.7	-4.7	-3.5	-5.9	-3.6	-6.2	-5.1	-4.7	-5.1	-3.9	-5.4	3.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.5	4.1	11.4	-1.9	-2.8	-2.4	-2.0	-2.5	-2.1	-1.3	-1.9	-2.1	-1.0	-2.1	-3.4	-0.9	-1.6	-2.6	-1.9	1.2
Wears glasses or contact lenses	3.5	4.0	10.2	-1.2	-2.5	-1.5	-2.2	-2.5	-2.6	-1.8	-2.0	-2.6	-1.1	-1.9	-2.0	-0.5	-2.3	-3.2	-2.6	0.1
Frequency of depressed mood in last 2 weeks	3.3	4.7	9.5	-1.1	-2.1	-1.3	-2.6	-2.6	-2.8	-2.0	-2.8	-2.5	-2.5	-1.7	-2.9	-0.1	-2.3	-1.6	-3.1	-1.5
Hip circumference	3.3	14.0	22.3	-4.4	-4.6	-4.1	-4.6	-4.5	-3.9	-3.2	-4.0	-4.4	-4.7	-4.6	-3.5	-2.8	-3.8	-2.6	-2.4	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.1	3.7	7.0	2.5	1.7	1.8	2.6	2.1	2.2	1.3	1.7	2.4	1.4	2.5	0.9	2.1	2.1	1.6	1.4	-2.0
Bipolar Disorder (2011)	3.0	2.9	8.7	0.9	1.6	0.9	2.2	2.1	3.0	1.4	1.4	2.0	0.6	1.5	1.1	-0.2	2.9	2.0	2.4	0.5
Medication: Amlodipine	3.0	4.2	6.7	2.3	2.0	1.6	2.1	2.4	2.1	2.3	2.5	2.5	1.9	2.6	1.3	1.7	2.6	1.6	2.2	-1.7
Arm fat-free mass (right)	3.0	15.3	24.8	-4.3	-5.0	-3.1	-4.6	-4.9	-4.7	-2.5	-4.2	-4.8	-4.5	-4.7	-4.2	-2.9	-3.8	-2.9	-3.7	1.6
Arm predicted mass (left)	3.0	15.4	23.5	-4.2	-4.8	-3.3	-4.5	-4.8	-4.6	-2.9	-4.3	-4.7	-4.8	-4.5	-4.4	-2.7	-3.8	-3.2	-3.7	1.5
Medication: Blood pressure	2.9	5.1	8.8	2.1	2.4	2.5	2.3	2.5	2.1	2.5	1.9	2.7	3.0	2.4	2.4	1.8	2.9	1.7	2.4	-1.3
Arm predicted mass (right)	2.9	15.0	24.3	-4.4	-4.9	-3.2	-4.6	-4.8	-4.5	-2.6	-4.0	-4.8	-4.6	-4.7	-4.0	-3.0	-3.8	-2.7	-3.6	1.7
Basal metabolic rate	2.9	15.9	25.4	-4.5	-4.9	-3.2	-4.7	-5.0	-4.8	-2.9	-4.3	-5.0	-4.6	-4.8	-4.1	-2.8	-4.0	-2.7	-3.8	1.5
Weight	2.8	13.7	22.1	-4.3	-4.3	-3.6	-4.3	-4.5	-4.2	-2.8	-4.4	-4.6	-4.7	-4.4	-3.5	-2.6	-3.7	-3.0	-2.7	1.3
Time employed in main current job	2.8	3.2	11.3	-2.3	-1.9	-2.0	-2.0	-1.8	-1.4	-1.3	-3.4	-1.9	-1.8	-2.1	-1.4	-2.2	-1.2	0.2	-0.5	1.8
Family relationship satisfaction	2.8	3.4	8.2	-1.5	-1.7	-0.7	-2.4	-2.4	-2.9	-1.2	-2.5	-2.4	-1.5	-1.8	-1.9	-0.6	-2.3	-2.2	-2.0	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	2.7	3.6	6.3	-1.3	-1.9	-1.7	-2.3	-2.1	-2.5	-2.2	-2.3	-2.0	-2.4	-1.7	-2.4	-0.3	-2.1	-1.3	-2.4	-0.7
Medication: Ramipril	2.7	3.4	8.4	1.9	1.3	1.3	2.4	1.8	2.2	2.9	1.4	1.8	1.2	2.0	1.5	1.9	2.5	1.9	2.6	-0.2
Leg fat-free mass (left)	2.6	13.7	22.9	-4.2	-4.5	-2.6	-4.4	-4.8	-4.6	-2.5	-4.0	-4.8	-4.0	-4.5	-3.9	-2.5	-3.8	-2.3	-4.0	1.0
Leg predicted mass (left)	2.6	13.7	22.7	-4.2	-4.5	-2.6	-4.4	-4.8	-4.6	-2.6	-4.0	-4.7	-4.0	-4.5	-3.9	-2.5	-3.9	-2.3	-4.0	1.0
Whole body fat-free mass	2.6	14.9	24.0	-4.2	-4.8	-2.9	-4.6	-4.9	-4.8	-2.7	-4.1	-4.8	-4.4	-4.6	-4.0	-2.7	-3.9	-2.4	-4.0	1.4
Leg fat-free mass (right)	2.6	13.7	23.7	-4.1	-4.6	-2.5	-4.5	-4.9	-4.6	-2.6	-3.7	-4.8	-3.9	-4.5	-3.9	-2.3	-4.0	-2.1	-4.1	0.8
Qualifications: nursing, teaching	2.6	4.1	17.6	-3.3	-1.6	-2.4	-2.8	-1.8	-1.3	-1.4	-1.3	-1.8	-1.3	-2.8	-1.0	-4.2	-1.8	-1.3	-0.7	1.3
Whole body water mass	2.6	14.8	24.2	-4.2	-4.8	-2.8	-4.6	-4.9	-4.8	-2.6	-4.0	-4.8	-4.3	-4.6	-4.0	-2.6	-3.9	-2.5	-4.0	1.3
Arm fat-free mass (left)	2.6	13.4	21.3	-4.0	-4.6	-3.1	-4.3	-4.5	-4.2	-2.9	-3.8	-4.4	-4.3	-4.3	-4.0	-2.7	-3.7	-2.9	-3.4	1.6
Ever depressed for a whole week	2.6	3.2	6.5	-1.5	-2.1	-1.2	-1.7	-2.6	-2.2	-0.6	-2.4	-2.5	-2.3	-2.2	-2.2	-1.0	-1.2	-1.6	-1.1	1.4
Leg predicted mass (right)	2.5	13.5	23.6	-4.0	-4.6	-2.5	-4.4	-4.9	-4.6	-2.5	-3.7	-4.8	-4.0	-4.5	-3.8	-2.2	-3.9	-2.1	-4.0	0.8
Trunk fat mass	2.4	10.1	15.2	-3.9	-3.2	-3.6	-3.8	-3.6	-3.3	-3.3	-3.5	-3.7	-3.8	-3.8	-2.3	-2.6	-3.5	-3.0	-2.1	1.4
Trunk fat-free mass	2.4	13.9	21.9	-4.1	-4.7	-2.9	-4.4	-4.7	-4.6	-2.6	-4.0	-4.6	-4.3	-4.4	-3.8	-2.8	-3.8	-2.3	-3.6	1.8
Financial situation satisfaction	2.4	3.0	8.5	-1.5	-1.7	-1.1	-2.0	-2.3	-2.6	-1.2	-2.9	-2.4	-1.1	-1.8	-1.5	-0.6	-1.5	-0.8	-2.2	-0.4
Ever smoked	2.4	4.2	9.5	-2.1	-2.3	-1.5	-2.1	-2.6	-2.9	-0.9	-3.1	-2.5	-2.9	-2.4	-0.9	-1.2	-2.2	-0.9	-1.7	1.0
Diverticular disease/diverticulitis (self-reported)	2.3	2.7	7.5	-1.8	-2.1	-1.8	-1.6	-1.9	-1.1	-0.8	-0.9	-1.9	-2.7	-1.7	-2.1	-1.4	-1.5	-1.2	-1.1	2.0
Allergy	2.3	5.3	9.1	2.8	2.8	2.1	3.0	3.0	2.9	2.0	2.2	2.8	1.4	3.0	2.0	1.8	2.5	2.0	1.8	-0.8
Fluid intelligence score	2.3	4.9	11.2	-2.4	-2.4	-1.6	-3.1	-2.9	-3.0	-1.7	-1.7	-2.9	-1.4	-2.7	-1.4	-1.7	-3.3	-2.5	-1.1	0.2
Trunk predicted mass	2.3	13.3	21.3	-4.0	-4.6	-2.8	-4.4	-4.6	-4.6	-2.7	-3.9	-4.5	-4.2	-4.3	-3.7	-2.6	-3.7	-2.3	-3.6	1.7
Shortness of breath walking on level ground	2.3	2.8	7.4	-1.9	-2.0	-1.9	-1.5	-2.0	-2.2	-1.6	-2.7	-2.1	-1.9	-2.1	-0.9	-1.0	-1.2	0.2	-0.8	1.0
Alzheimer’s Disease (in mother)	2.2	2.5	6.9	1.5	1.9	2.1	1.8	1.5	1.1	1.1	-0.2	1.2	2.4	1.8	2.6	1.4	1.7	1.7	1.6	-0.3
Age when periods started (menarche)	2.2	5.3	10.3	2.5	3.0	2.3	2.7	2.8	2.6	2.5	1.2	2.8	2.8	2.9	1.5	1.7	3.2	0.9	1.6	-1.9
Happiness	2.2	2.6	7.5	-1.2	-1.3	-0.8	-2.1	-2.2	-2.7	-0.7	-2.1	-2.2	-1.6	-1.5	-1.7	-0.6	-1.6	-0.9	-2.4	-0.4
Medication for cholesterol, blood pressure or diabetes	2.2	3.7	6.0	-2.1	-2.0	-2.4	-1.9	-1.9	-1.5	-2.3	-1.1	-1.9	-2.0	-2.2	-2.2	-2.4	-2.2	-1.6	-1.7	1.7
Mineral and other dietary supplements	2.2	3.0	6.8	-2.1	-1.6	-2.3	-2.1	-1.4	-1.5	-0.5	-1.9	-1.6	-0.3	-1.9	-2.6	-2.0	-1.2	-1.9	-1.0	2.4
Miserableness	2.2	3.9	9.1	-1.6	-2.1	-1.1	-2.5	-2.6	-3.0	-2.3	-2.0	-2.6	-1.4	-2.0	-0.9	-0.1	-2.5	-0.9	-2.5	-1.7
Major Depression (MDD)	2.1	2.5	5.2	-2.1	-1.4	-2.3	-2.1	-1.5	-1.5	-1.1	-0.9	-1.6	-2.1	-1.9	-1.1	-2.1	-1.5	-1.2	-0.1	1.7
Lung FVC	2.1	10.9	21.7	-2.2	-3.6	-3.0	-3.0	-4.1	-4.5	-3.0	-4.1	-4.2	-4.7	-3.1	-2.7	-0.9	-4.5	-2.9	-3.1	1.3
Neuroticism	2.1	5.0	13.2	-1.3	-2.6	-1.0	-2.4	-3.1	-3.6	-2.4	-2.9	-3.0	-2.9	-2.0	-1.9	0.3	-2.3	-1.0	-2.1	-1.0
Tinnitus: Yes, but not now, but have in the past	2.1	2.3	7.0	-1.5	-2.3	-2.1	-1.2	-1.6	-1.4	-0.6	-2.3	-1.4	-1.1	-1.5	-2.6	-0.5	-0.9	-0.7	-1.4	1.2
Commuting to job workplace: Walk	2.1	2.3	4.5	1.6	1.4	1.7	1.5	1.6	1.1	2.1	1.1	1.8	1.9	1.6	1.8	1.4	1.7	1.1	1.2	-0.7
Eye problems/disorders: Cataract	2.1	2.5	4.4	-1.5	-1.6	-1.1	-1.6	-2.0	-1.8	-1.8	-2.0	-2.1	-0.6	-1.8	-1.1	-1.3	-1.4	-1.8	-2.1	0.5
Risk taking	2.1	3.0	13.1	-1.9	-2.1	-1.0	-1.7	-2.3	-1.8	-0.1	-0.7	-2.2	-3.6	-2.1	-2.2	-0.7	-1.5	-0.8	-1.1	1.5
BMI	2.0	11.6	25.7	-3.5	-3.9	-2.7	-3.7	-4.3	-4.0	-1.0	-4.9	-4.5	-5.1	-3.7	-3.8	-1.5	-2.8	-3.6	-2.0	-0.0
Allergy or Eczema	2.0	5.3	11.5	-3.1	-2.3	-2.4	-3.4	-2.6	-2.3	-3.2	-1.8	-2.4	-0.5	-2.9	-0.8	-3.0	-2.6	-1.9	-1.1	1.3
Ever highly irritable/argumentative for 2 days	2.0	2.4	5.0	-2.2	-1.6	-1.0	-1.7	-1.6	-1.3	-1.6	-1.6	-1.7	-1.0	-2.0	-1.6	-2.2	-1.4	-0.4	-1.7	1.1
Mouth/teeth dental problems: Loose teeth	2.0	2.4	6.9	1.8	2.2	2.6	0.9	1.2	0.8	1.4	0.8	1.1	1.4	1.9	2.3	2.0	0.5	-0.3	0.6	-2.3
Ever had hysterectomy (womb removed)	1.9	2.1	4.7	-2.1	-1.2	-1.6	-1.8	-1.7	-1.1	-1.8	0.1	-1.9	-0.6	-1.9	-0.7	-2.2	-1.7	0.4	-0.6	1.7
Systolic blood pressure, automated reading	1.9	5.4	12.2	2.2	2.9	0.9	3.1	3.1	2.9	1.9	2.0	3.0	0.7	2.6	2.7	1.1	2.8	1.6	3.5	-1.1
Qualifications: None of the above	1.9	4.2	10.0	2.9	1.9	0.3	3.2	2.7	2.9	1.4	0.7	2.6	0.4	3.0	0.7	2.5	2.7	0.7	1.9	-0.7
Gout (self-reported)	1.9	2.6	5.2	-2.2	-1.9	-2.2	-2.2	-1.6	-1.2	-1.0	-1.5	-1.3	-0.6	-2.2	-2.3	-2.2	-1.5	-0.7	-1.1	0.6
Whole body fat mass	1.9	7.8	14.2	-3.3	-2.8	-3.3	-3.3	-3.2	-2.9	-2.6	-3.4	-3.3	-3.8	-3.3	-2.1	-2.0	-2.9	-2.7	-1.7	0.8
Arm fat mass (left)	1.9	7.9	16.4	-3.1	-2.9	-3.0	-3.1	-3.3	-3.0	-2.3	-3.7	-3.4	-4.0	-3.2	-2.2	-1.7	-3.0	-2.5	-1.7	0.6
Supplements: Fish oil (including cod liver oil)	1.9	2.4	5.5	1.8	1.6	1.7	2.3	1.5	1.8	0.9	1.7	1.4	0.1	1.6	1.6	1.4	1.4	1.4	1.4	-2.3
Neuroticism (Nagel 2018)	1.8	4.2	9.6	-1.3	-2.3	-0.8	-2.2	-2.7	-3.1	-1.6	-2.3	-2.7	-3.1	-1.9	-1.9	0.3	-1.6	-2.8	-1.9	-1.0
Other serious medical condition/disability diagnosed by doctor	1.8	2.4	6.4	-0.7	-1.4	-1.0	-2.2	-1.6	-2.1	-1.7	-1.7	-1.7	-2.5	-0.8	-1.1	1.1	-2.2	-1.3	-1.7	-0.6
Arm fat mass (right)	1.8	7.4	16.1	-3.0	-2.8	-3.1	-3.1	-3.2	-3.0	-2.2	-3.6	-3.3	-4.0	-3.1	-2.3	-1.6	-2.9	-2.4	-1.6	0.4
Heart disease (mother)	1.8	2.2	5.7	-2.1	-1.1	-1.0	-1.7	-1.7	-2.4	-0.9	-1.6	-1.9	-1.0	-2.0	-0.2	-1.8	-1.4	-0.6	-1.0	1.6
Leg fat mass (right)	1.8	7.1	12.8	-3.4	-2.8	-3.3	-3.0	-2.9	-2.5	-2.1	-3.5	-3.1	-3.6	-3.2	-2.1	-2.3	-2.4	-2.4	-1.2	1.3
Pain type(s) experienced in last month: Hip pain	1.8	2.2	5.5	-1.2	-2.2	-1.1	-1.4	-2.1	-1.8	-0.4	-1.7	-2.2	-2.4	-1.4	-2.2	0.3	-0.8	0.2	-0.9	-1.0
Leg fat mass (left)	1.8	7.2	13.5	-3.4	-2.9	-3.3	-3.0	-3.0	-2.5	-2.2	-3.5	-3.1	-3.7	-3.2	-2.0	-2.2	-2.5	-2.4	-1.2	1.3
Trunk fat percentage	1.7	6.6	11.2	-3.2	-2.4	-3.4	-3.0	-2.8	-2.4	-3.0	-2.8	-2.9	-3.1	-3.1	-1.6	-2.1	-2.9	-2.7	-1.2	1.0
Financial difficulties in last 2 years	1.7	2.3	7.8	-1.3	-1.1	-0.5	-1.7	-1.8	-2.8	0.4	-2.2	-1.8	-0.8	-1.5	-1.5	-0.4	-1.3	-1.4	-2.6	0.1
Standing height	1.7	16.5	26.7	-5.2	-5.0	-4.0	-4.8	-4.6	-4.0	-4.5	-2.3	-4.5	-3.3	-5.1	-3.6	-4.6	-4.1	-1.8	-3.9	4.2
Birth weight	1.7	3.8	8.2	-2.0	-2.2	-0.7	-2.3	-2.7	-2.5	-2.7	-1.0	-2.6	-0.3	-2.3	0.1	-1.2	-2.9	-1.6	-2.2	1.5
Number of full brothers	1.7	2.1	6.2	-1.5	-1.6	-0.6	-1.4	-1.7	-1.4	-0.8	-2.2	-1.9	-2.5	-1.4	-1.0	-0.7	-1.1	-0.3	-1.5	1.9
Neck or shoulder pain in last month	1.7	2.4	9.3	-1.3	-1.5	-0.5	-1.4	-2.0	-1.7	-1.4	-1.2	-1.9	-1.4	-1.6	-2.0	-0.6	-1.9	-1.2	-3.0	-0.1
Primary Biliary Cirrhosis	1.6	2.3	5.9	-1.9	-2.0	-2.4	-1.3	-1.5	-0.9	-1.2	-1.5	-1.7	-0.5	-1.9	-1.8	-2.0	-1.1	-0.9	-1.2	1.6
Ever used hormone-replacement therapy (HRT)	1.6	2.0	4.4	-1.5	-1.4	-1.7	-1.4	-1.5	-1.3	-1.0	-1.8	-1.4	-1.1	-1.4	-2.1	-1.3	-1.0	-1.5	-1.3	1.7
Fed-up feelings	1.6	2.9	9.2	-0.1	-1.4	-0.2	-1.6	-2.0	-2.6	-1.5	-2.5	-1.9	-1.4	-0.9	-2.3	1.0	-1.8	-0.8	-3.0	-1.6
Heart attack	1.6	2.1	5.1	1.3	1.5	1.5	1.9	1.6	1.1	2.2	-0.3	1.5	0.4	1.6	1.5	1.5	2.0	1.3	1.8	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.4	8.8	-1.3	-2.5	-3.0	-1.6	-2.2	-2.5	-1.4	-2.0	-2.2	-2.1	-1.7	-0.9	-0.9	-2.2	-1.8	-1.1	1.1
Ever had prostate specific antigen (PSA) test	1.6	1.9	4.8	-1.0	-1.6	-0.8	-1.3	-2.0	-2.1	-1.3	-1.7	-2.2	-1.3	-1.4	-1.3	-0.2	-1.5	-0.7	-1.5	0.2
Crohns Disease (2017)	1.5	3.3	7.7	-2.4	-1.9	-2.8	-2.0	-2.0	-1.3	-2.0	-1.8	-2.1	-1.4	-2.3	-0.9	-2.5	-2.1	-0.9	-0.5	0.9
Waist Hip Ratio (WHR)	1.5	6.6	15.9	3.4	2.5	2.1	4.0	3.0	3.1	3.0	1.0	2.8	1.5	3.6	2.5	2.8	3.1	1.7	1.3	-0.5
Alcohol intake versus 10 years previously	1.5	2.2	6.8	1.9	1.4	2.3	1.2	1.1	0.5	2.0	0.3	1.1	1.4	1.7	1.2	2.2	1.2	-0.8	0.0	-2.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.4	5.7	-1.5	-1.5	-0.6	-1.5	-2.0	-2.0	-1.5	-2.4	-2.2	-1.4	-1.5	-1.5	-1.4	-1.3	-1.4	-1.4	1.1
Chest pain or discomfort	1.5	2.1	6.8	-1.1	-1.3	-0.8	-1.7	-1.8	-2.6	-2.3	-1.9	-1.8	-0.3	-1.3	-1.0	-0.7	-1.7	-0.6	-1.7	0.2
Osteoarthritis (self-reported)	1.5	1.9	6.2	-1.6	-1.6	0.0	-1.2	-1.9	-0.9	-0.8	-1.3	-1.9	-2.5	-1.8	-2.0	-0.8	-1.0	-0.7	-1.3	0.1
Heart attack/myocardial infarction (self-reported)	1.5	2.0	5.2	1.4	1.5	1.2	1.9	1.6	1.1	2.3	-0.2	1.5	0.1	1.6	1.4	1.4	1.9	1.0	2.0	-0.1
Blood clot in the leg (DVT)	1.4	1.8	7.2	-1.7	-0.5	-0.7	-1.7	-1.2	-1.2	-2.7	-1.4	-1.3	-0.7	-1.4	-0.2	-1.1	-2.2	-0.6	-1.7	-0.1
Health satisfaction	1.4	1.8	7.4	0.1	-1.2	-0.5	-1.0	-1.3	-1.5	-1.5	-2.1	-1.6	-2.7	-0.3	-1.4	1.5	-1.2	0.0	-1.3	-1.4
Handedness (chirality/laterality): Left-handed	1.4	1.7	4.7	2.0	1.4	1.1	1.2	1.1	0.3	1.0	1.6	1.1	1.2	1.6	0.9	2.1	0.4	0.7	0.3	-2.2
Commuting to job workplace: Public transport	1.4	1.7	4.8	-1.7	-0.9	0.3	-1.7	-2.0	-2.2	0.5	-1.0	-1.6	0.6	-2.0	-0.5	-1.3	-0.8	-1.2	-1.6	-0.5
Bipolar Disorder (2018)	1.3	2.0	4.9	1.0	1.3	1.2	1.7	1.9	2.2	1.0	1.1	2.0	1.9	1.4	0.1	0.3	2.2	0.5	1.2	1.1
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	5.9	-0.7	-1.5	-1.3	-1.3	-1.1	-1.3	-0.7	-0.4	-0.7	-1.1	-1.1	-1.3	-0.1	-1.7	-2.4	-1.2	0.6
Waist circumference	1.3	4.7	11.4	-2.3	-2.5	-2.5	-2.1	-2.6	-2.4	-1.0	-3.3	-2.7	-3.4	-2.4	-1.5	-1.1	-1.8	-2.3	-1.2	0.8
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	6.1	-0.6	-0.5	-0.9	-1.9	-1.6	-2.5	-1.6	-2.1	-1.6	-1.6	-0.9	-0.3	-0.0	-1.9	-0.8	-2.1	-1.0
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.7	8.1	0.1	-1.4	0.1	-0.4	-1.1	-1.0	-0.6	-2.2	-0.9	-1.7	-0.4	-2.8	0.9	-0.3	-0.8	-2.1	-1.6
Body fat percentage	1.3	5.1	9.4	-2.7	-2.0	-3.1	-2.6	-2.4	-2.1	-2.6	-2.8	-2.6	-3.1	-2.6	-1.3	-1.5	-2.4	-2.5	-0.9	0.6
Qualifications: College or University degree	1.3	4.1	10.6	-2.5	-1.8	-2.2	-3.2	-2.3	-2.6	-2.1	-1.2	-2.2	-1.8	-2.6	-0.3	-2.5	-2.6	-0.5	-0.1	1.5
Leg pain on walking	1.3	1.7	4.1	-0.9	-1.5	-0.7	-1.2	-1.6	-1.7	-1.1	-2.0	-1.8	-1.7	-1.0	-1.5	-0.0	-1.2	0.0	-1.8	0.1
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	6.6	-1.5	-1.4	-1.3	-1.4	-1.1	-0.6	-1.5	-0.4	-0.9	0.1	-1.4	-0.9	-1.0	-1.1	-2.6	0.1	0.4
Medication: Paracetamol	1.3	2.1	8.8	1.2	1.7	2.3	1.2	1.3	1.3	1.4	0.4	1.4	3.0	1.4	0.7	0.8	1.9	0.9	-0.7	-1.3
Average weekly beer plus cider intake	1.3	1.9	3.7	1.5	1.9	1.3	1.0	1.4	1.1	1.9	0.6	1.4	1.6	1.6	1.6	1.5	1.5	0.9	0.2	-1.8
Mean Putamen Volume	1.2	1.4	3.9	-1.1	-0.9	-1.5	-1.5	-1.2	-1.1	-1.0	-2.0	-1.3	-1.5	-1.1	-0.9	-0.7	-1.0	-1.3	-1.3	0.3
Height	1.2	22.5	41.8	-6.5	-5.0	-4.4	-5.4	-5.1	-4.3	-5.0	-3.0	-5.3	-3.2	-6.3	-2.8	-6.4	-5.0	-1.5	-4.6	6.0
Hayfever, allergic rhinitis or eczema	1.2	2.5	5.2	-2.0	-1.6	-1.6	-2.3	-1.8	-1.5	-1.9	-0.9	-1.8	0.0	-2.0	-0.9	-2.3	-1.7	-1.7	-1.0	1.2
Past tobacco smoking	1.2	2.2	8.3	1.6	1.6	0.9	1.3	2.0	2.2	-0.0	2.9	2.0	1.8	1.8	0.7	0.8	1.3	0.6	1.0	-0.1
Number of children fathered	1.2	1.4	2.9	-1.1	-1.1	-1.6	-1.0	-0.9	-0.8	-1.7	-1.2	-1.1	-1.7	-1.0	-1.5	-0.9	-0.7	-1.3	-1.2	1.4
Long-standing illness, disability or infirmity	1.2	1.9	7.4	-0.8	-1.1	-1.3	-1.8	-1.5	-1.5	-2.4	-1.0	-1.4	-2.7	-0.9	-0.4	0.7	-2.0	0.0	-0.6	-0.3
Alcohol drinker status: Never	1.2	1.5	5.1	1.3	1.4	0.6	1.0	1.6	2.3	-0.1	1.4	1.4	0.2	1.5	1.1	1.1	0.9	0.4	2.2	0.1
Commuting to job workplace: Cycle	1.2	1.4	4.7	-1.2	-1.2	-0.7	-1.6	-1.0	-0.9	-0.7	-2.2	-1.2	-0.3	-1.1	0.0	-1.3	-1.4	-1.2	-1.6	1.6
Body mass index (BMI)	1.1	4.8	13.0	-2.2	-2.2	-2.1	-2.3	-2.6	-2.6	-1.1	-3.6	-2.7	-3.5	-2.3	-1.9	-0.7	-2.1	-2.4	-1.1	-0.4
Hair/balding pattern: Pattern 4	1.1	2.7	5.8	1.2	2.4	2.1	1.9	2.0	2.0	1.1	1.8	1.7	2.2	1.7	2.1	0.1	1.6	1.6	0.7	0.3
Loud music exposure frequency	1.1	1.2	2.9	-1.4	-1.7	-1.2	-0.8	-1.3	-0.4	-0.3	-1.0	-1.4	-0.8	-1.4	-1.2	-1.0	-0.4	-1.3	0.4	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	4.2	-1.5	-1.4	-0.8	-1.2	-1.7	-1.6	-0.4	-0.5	-2.0	-1.7	-1.5	-1.3	-0.6	-0.7	-0.2	-0.4	1.1
Wheeze or whistling in the chest in last year	1.1	2.0	8.6	-1.0	-1.4	-0.6	-0.6	-1.8	-2.0	0.6	-2.5	-1.7	-2.9	-1.4	-1.8	-0.0	-0.3	-0.8	-0.5	-1.0
Emphysema/chronic bronchitis	1.1	1.2	5.4	-0.4	-1.0	-0.4	-0.7	-1.3	-2.3	-0.4	-1.1	-1.2	-1.5	-0.8	-1.1	0.7	-1.1	0.1	-1.6	-1.2
Overall health rating	1.1	2.3	8.1	1.6	1.2	0.0	1.3	1.2	1.1	-0.7	-0.4	1.2	-1.0	1.7	2.6	2.3	0.8	2.8	1.8	-2.0
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	6.2	-1.8	-2.1	-2.5	-2.1	-1.5	-1.3	-2.5	-0.2	-1.3	-1.1	-1.6	-1.8	-1.0	-1.5	0.4	-0.9	0.6
LDL Cholesterol	1.0	1.6	4.3	1.6	0.9	-0.1	1.5	1.2	0.8	1.1	0.8	1.2	0.5	1.4	1.0	1.6	1.3	1.7	2.1	-1.5
Neuroticism (2016)	1.0	1.4	4.8	-0.4	-1.0	0.3	-0.9	-1.6	-2.2	-0.9	-1.6	-1.4	-1.0	-0.9	-0.3	0.5	-1.5	-1.4	-1.5	-1.5
Qualifications: CSEs or equivalent	1.0	1.3	5.9	-1.5	-0.8	-0.4	-0.6	-0.9	-0.2	-1.5	-1.2	-1.2	-0.6	-1.2	-1.6	-1.6	-0.5	-0.2	-2.4	0.9
Mouth/teeth dental problems	1.0	1.5	5.0	-1.0	-1.6	-2.2	-1.1	-1.1	-1.1	-0.0	-0.6	-0.9	-1.3	-1.1	-2.2	-0.6	-0.6	-1.5	-1.3	0.7
Leg fat percentage (right)	1.0	3.7	9.7	-2.3	-1.7	-3.1	-2.0	-1.8	-1.4	-2.0	-2.8	-2.0	-2.9	-2.0	-0.9	-1.6	-1.6	-2.3	0.1	1.1
Leg fat percentage (left)	1.0	3.7	9.8	-2.2	-1.9	-3.1	-2.0	-1.8	-1.4	-2.1	-2.6	-2.0	-3.0	-2.0	-0.9	-1.3	-1.7	-2.2	0.0	1.0
Fasting Glucose	0.9	1.1	2.8	0.6	1.2	0.9	1.1	1.0	1.2	1.6	0.9	-0.4	1.2	0.7	0.9	0.2	1.6	1.1	1.7	0.1
Hearing difficulty/problems with background noise	0.9	1.5	5.7	-0.4	-1.3	0.3	-0.9	-1.6	-2.0	-1.3	-2.4	-1.7	0.1	-0.7	-0.5	0.8	-0.6	-1.2	-2.1	-0.6
Neuroticism score	0.9	2.0	6.2	-0.1	-1.6	-0.2	-1.2	-2.0	-2.5	-1.6	-1.7	-2.0	-1.8	-0.8	-1.1	1.1	-1.3	0.3	-1.3	-1.7
Prospective memory result	0.9	1.1	3.2	1.3	0.6	0.3	1.7	1.1	0.9	1.2	-0.1	1.1	-0.9	1.3	0.8	1.3	1.8	0.4	1.1	0.7
Lung cancer (father)	0.9	1.0	5.1	0.6	1.1	1.0	0.7	1.0	1.4	1.2	1.5	1.0	-0.5	0.9	0.4	0.1	0.7	0.6	2.3	-0.7
Medication: Ventolin 100micrograms inhaler	0.9	1.2	3.8	1.6	1.2	1.0	1.1	0.8	0.0	0.8	0.4	1.2	0.4	1.2	1.7	1.9	0.8	0.0	0.9	-1.5
Age at last live birth	0.9	1.3	7.3	-1.2	0.2	-0.3	-1.7	-0.1	-0.1	-2.7	0.7	-0.5	1.2	-0.8	-0.1	-1.8	-1.8	-0.9	-0.7	0.4
Arm fat percentage (left)	0.9	3.5	8.6	-2.0	-1.5	-2.3	-2.1	-2.1	-1.9	-1.7	-2.8	-2.3	-2.9	-2.0	-0.9	-0.8	-2.2	-1.7	-0.8	-0.1
Illnesses of father: None of the above (group 1)	0.9	1.1	3.5	-0.9	-1.2	-0.7	-0.7	-0.9	-0.7	0.8	-1.0	-0.7	-0.3	-1.1	-1.9	-0.7	-0.1	-1.9	-1.3	1.4
Ever taken oral contraceptive pill	0.9	1.0	5.4	0.9	0.8	1.8	0.3	0.6	0.7	-0.4	0.6	0.7	1.3	0.8	1.3	1.0	0.3	1.2	-0.2	-2.3
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	5.6	-1.5	-0.3	-0.5	-1.3	-0.8	-0.7	-2.4	-1.1	-0.9	-0.1	-1.1	0.0	-1.1	-1.8	-0.3	-1.4	0.0
Ovarian Cancer	0.8	1.0	2.6	-1.2	-1.0	-0.6	-1.2	-0.9	-1.1	-0.5	-0.7	-0.8	-1.6	-1.3	0.1	-1.4	-1.1	-0.3	-1.0	1.5
Chronotype (morning person)	0.8	1.8	5.2	-0.5	-1.3	-1.6	-0.8	-0.9	-0.9	-1.7	-1.7	-1.4	-1.3	-0.6	-2.0	-0.1	-1.4	-2.1	-2.3	0.6
Number of incorrect matches in round	0.8	1.3	2.8	1.0	0.8	0.7	1.6	1.1	1.7	1.3	1.4	1.0	0.9	1.1	1.3	0.2	1.4	1.1	1.4	0.6
Number of live births	0.8	1.2	3.1	1.2	1.8	1.1	0.9	1.4	0.8	-0.2	1.0	1.3	1.6	1.3	1.5	0.9	0.8	0.3	0.4	-1.3
Medication: Cholesterol lowering	0.8	1.2	3.4	1.2	1.4	1.8	1.0	0.9	0.3	1.0	-0.1	0.7	1.0	1.2	1.7	1.8	0.6	0.4	0.5	-1.3
Exposure to tobacco smoke outside home	0.8	1.1	4.2	1.2	1.0	1.5	0.9	0.4	0.1	1.1	-1.4	0.5	1.1	0.9	0.1	1.8	0.9	-1.1	-0.1	-2.0
Worry too long after embarrassment	0.8	1.3	7.1	0.2	-1.1	-1.4	-0.2	-1.2	-1.6	-0.0	-1.0	-1.1	-2.7	-0.4	-0.0	1.5	0.0	1.0	1.4	-1.1
Mean time to correctly identify matches	0.8	1.4	11.2	0.4	0.8	-0.5	0.0	0.3	-0.5	-0.9	-0.6	0.3	-2.0	0.3	3.3	0.5	-0.5	-0.2	2.6	0.8
Comparative height size at age 10	0.8	4.2	8.8	-3.0	-2.8	-1.5	-2.5	-2.6	-2.0	-2.0	-0.8	-2.3	-1.1	-2.9	-1.0	-2.6	-1.8	-0.5	-1.5	2.5
Hypertension (Self-reported)	0.8	2.3	4.7	1.9	1.1	1.1	1.4	1.6	1.2	2.1	0.6	1.6	0.4	2.2	1.0	2.1	1.8	0.8	1.9	-2.2
Medication: Aspirin	0.8	1.0	2.2	1.1	1.3	1.2	1.1	1.3	1.1	0.2	0.1	1.1	0.8	1.4	1.0	0.8	0.6	1.5	0.7	-0.5
Irritable Bowel Disease (IBD)	0.7	1.6	5.5	-1.5	-1.3	-2.3	-1.2	-1.3	-1.2	-0.8	-1.7	-1.4	-1.2	-1.4	-0.7	-1.7	-1.1	-0.5	0.4	0.1
Smoking Status	0.7	1.7	8.4	-0.3	-1.4	-0.4	-0.3	-1.4	-1.4	0.5	-2.6	-1.3	-2.9	-0.9	-1.7	0.7	-0.5	-0.9	-1.2	-0.3
Relative age of first facial hair	0.7	1.4	4.5	-1.2	-1.1	-1.7	-1.2	-1.4	-0.8	-0.7	-1.1	-1.4	-1.7	-1.3	-2.1	-1.0	-1.0	-0.4	-1.2	0.4
Taking other prescription medications	0.7	1.1	4.4	-0.6	-1.1	-0.6	-1.5	-1.1	-1.1	-1.9	-0.7	-0.9	-1.6	-0.8	-0.6	0.1	-2.1	0.7	0.1	0.3
Stomach or abdominal pain in last month	0.7	0.9	4.5	0.9	1.2	1.1	0.9	1.1	0.3	0.4	0.2	1.2	2.1	1.0	0.7	0.7	0.8	0.5	-0.5	-0.8
Medication: Atenolol	0.7	0.9	2.2	0.8	1.1	0.5	1.1	1.3	1.3	0.2	0.4	1.5	1.1	1.1	0.7	0.2	1.0	0.9	1.0	0.9
Arm fat percentage (right)	0.7	2.8	7.7	-1.7	-1.3	-2.3	-1.7	-1.9	-1.7	-1.6	-2.5	-2.0	-2.8	-1.7	-0.9	-0.6	-1.9	-1.7	-0.6	-0.3
Worrier / anxious feelings	0.7	1.3	4.4	2.0	0.9	2.0	1.2	0.7	0.2	0.4	0.7	0.6	0.3	1.5	0.8	2.1	0.6	0.7	0.3	-2.0
Illnesses of mother	0.7	0.8	2.0	-1.4	-1.2	-0.8	-0.6	-1.0	-0.6	-0.5	-0.4	-1.1	-0.7	-1.2	-1.4	-1.1	-0.4	-0.4	-1.2	0.8
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	8.1	-0.9	0.4	-0.2	-0.7	-0.1	-0.1	0.2	1.4	0.0	0.7	-0.7	1.6	-1.4	-0.9	2.9	1.0	0.6
Age at first live birth	0.7	1.2	7.6	-0.9	-0.0	-0.6	-1.9	-0.1	0.0	-2.8	1.1	-0.4	1.0	-0.5	-0.3	-1.6	-1.6	-0.6	-0.8	0.3
Medication: Ibuprofen	0.7	0.8	5.0	0.8	-0.3	0.8	0.5	0.1	-0.3	0.4	-1.3	0.3	-0.6	0.5	-1.5	1.3	0.7	-0.1	-1.3	-2.2
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	3.6	0.8	1.1	1.9	0.9	0.4	-0.2	1.5	0.4	0.2	0.6	0.8	-0.0	1.1	0.3	-0.1	-1.7	-0.3
Smoking status: Previous	0.7	1.1	5.7	-1.0	-1.1	-0.3	-0.8	-1.5	-1.5	0.4	-2.4	-1.5	-0.7	-1.3	-0.4	-0.3	-0.6	-0.4	-0.8	-0.6
Mood swings	0.7	1.3	5.7	-0.3	-0.7	-0.3	-1.6	-0.9	-1.6	-2.4	-1.4	-0.7	0.0	-0.5	-0.8	-0.0	-1.4	-0.8	-1.7	-1.6
Myopia	0.7	1.0	3.6	1.1	1.4	0.1	0.8	1.3	1.2	-0.4	0.7	1.0	0.5	1.2	1.9	1.4	0.2	0.5	1.5	-0.5
Supplements: Calcium	0.7	0.8	5.2	1.0	-0.1	1.4	0.4	0.1	-0.3	-0.7	0.5	0.4	0.7	0.4	0.8	1.7	-0.2	0.1	-0.4	-2.3
Heart disease (siblings)	0.7	0.8	2.0	-0.9	-0.7	-0.7	-1.2	-0.9	-1.4	-0.4	-1.2	-1.1	-1.2	-0.8	-0.0	-0.2	-1.3	-1.2	-0.4	-0.7
Reaction Time	0.6	1.2	6.1	-0.4	0.2	-1.0	-0.8	-0.4	-0.9	-1.6	-0.8	-0.3	-1.7	-0.5	2.5	-0.3	-1.1	0.1	1.8	1.5
Body Mass Index (BMI) (2010)	0.6	0.9	2.1	-1.4	-1.0	-0.8	-0.4	-1.0	-0.5	0.7	-1.0	-1.0	-1.1	-1.3	-1.2	-1.3	0.2	0.2	-0.1	1.5
Coronary Artery Disease (CAD)	0.6	0.7	2.3	-0.0	-0.8	-1.0	-0.3	-1.0	-0.2	0.5	-1.2	-1.1	-1.5	-0.4	-1.5	0.6	-0.2	-0.1	-1.5	-0.5
Lupus	0.6	0.9	3.1	-0.9	-0.2	-0.5	-1.2	-0.8	-1.7	-0.0	-1.3	-0.8	-0.7	-0.8	-0.7	-0.8	-1.2	-0.2	-1.2	1.2
Type 2 Diabetes (T2D) (2018)	0.6	1.0	8.1	1.6	0.1	0.2	0.2	0.6	-0.5	0.7	0.9	0.6	-0.5	1.3	0.7	2.8	-0.5	-1.1	0.3	-1.3
Supplements: Zinc	0.6	0.6	2.9	-0.1	-0.5	-1.3	-0.6	-0.4	-0.6	-1.7	-0.8	-0.4	-0.9	-0.3	-0.3	-0.3	-1.3	-0.5	-1.2	-0.1
Severe depression (siblings)	0.6	0.6	1.6	0.0	1.2	0.5	0.2	1.1	1.0	-0.4	1.3	1.0	-0.5	0.5	0.3	-1.0	-0.1	1.2	1.2	0.5
Impedance of leg (right)	0.6	3.0	8.1	0.3	1.6	-1.4	1.3	2.2	2.8	-0.9	2.2	2.1	1.8	1.1	1.8	-1.3	1.8	0.5	2.5	2.4
Current tobacco smoking	0.6	1.0	7.4	-0.5	-1.1	-1.0	-0.6	-1.0	-0.7	-1.0	-1.0	-0.9	-2.7	-0.8	-0.9	0.3	-0.8	-0.8	-0.7	0.8
Medication: Levothyroxine sodium	0.6	1.0	2.9	1.4	0.9	-0.0	0.8	1.1	0.7	-0.7	1.2	1.1	-0.3	1.3	1.5	1.5	0.2	-0.2	1.7	-1.0
Impedance of leg (left)	0.6	3.0	8.3	0.4	1.4	-1.4	1.2	2.2	2.9	-1.2	2.5	2.1	1.8	1.0	2.0	-1.1	1.5	0.8	2.5	2.3
Impedance of arm (right)	0.6	2.9	8.0	1.0	2.1	-0.1	1.6	2.1	2.5	-0.7	2.7	2.1	2.8	1.5	1.8	-0.1	1.4	1.7	1.5	1.0
Falls in the last year	0.6	0.8	3.2	0.1	-0.5	-0.2	-1.2	-0.8	-1.7	-0.7	-0.4	-0.8	-0.3	-0.4	-0.6	0.9	-1.0	-0.7	-0.8	-1.8
Pulse rate	0.6	1.0	3.9	0.3	1.1	2.0	0.6	-0.1	-0.6	0.8	0.4	-0.2	1.9	0.1	-0.2	-0.1	0.3	1.3	-1.8	-1.5
Qualifications: A levels/AS levels or equivalent	0.6	1.4	3.8	-1.3	-1.4	-0.9	-1.9	-1.5	-1.1	-0.6	-0.9	-1.6	-0.5	-1.4	-0.9	-1.4	-1.6	-0.9	-0.4	0.2
Medication: Lansoprazole	0.6	0.6	2.1	0.5	-0.2	0.8	-0.6	-0.5	-0.7	-1.0	0.5	-0.4	-0.3	0.2	-0.5	1.4	-1.3	-1.4	-0.7	-1.2
Medication: Paracetamol	0.6	1.0	3.2	0.9	1.1	1.8	0.8	0.8	1.2	0.8	0.4	0.8	1.6	1.0	-0.3	0.6	1.1	1.4	-0.8	-0.8
Glaucoma (self-reported)	0.6	0.7	7.2	-0.4	-0.6	-0.5	-0.8	-0.5	-0.0	-2.7	0.3	-0.5	-0.8	-0.4	0.6	-0.6	-1.3	-0.4	0.6	-0.2
Medication for pain relief, constipation, heartburn	0.6	1.0	5.0	-0.5	0.3	-1.1	0.0	0.4	0.3	-0.4	1.6	0.5	0.6	-0.4	2.2	-1.2	-0.1	-0.4	1.9	1.5
Supplements: Vitamin C	0.6	0.7	2.3	1.0	0.5	0.9	1.1	0.7	0.8	0.6	1.5	0.7	0.1	0.8	0.9	0.5	0.8	0.3	0.9	-1.5
Diabetes diagnosed by doctor	0.6	0.9	4.9	1.2	0.1	0.0	0.1	0.6	-0.1	1.1	1.5	0.5	-0.5	1.1	0.7	2.2	-0.3	-1.3	0.9	-1.4
Back pain experienced in last month	0.6	0.8	4.6	0.6	-0.7	-1.0	-0.2	-0.6	-0.9	1.2	-0.9	-0.4	-2.1	0.3	-0.4	1.7	-0.4	0.1	-0.1	-1.0
Medication: Lisinopril	0.6	0.7	2.1	1.3	0.3	0.1	0.6	0.9	0.7	1.3	0.3	0.9	0.3	1.3	0.6	1.4	0.8	0.0	0.8	-1.4
Illnesses of father: High blood pressure	0.6	0.7	1.9	-1.0	-1.1	-1.2	-0.6	-0.6	-0.2	-1.1	0.8	-0.6	0.1	-1.1	-0.8	-1.4	-0.8	0.2	0.0	1.2
Age started oral contraceptive pill	0.6	0.8	2.9	-0.6	-1.0	-0.5	-1.0	-1.0	-0.6	-1.0	-0.1	-0.8	-1.4	-0.8	0.0	-0.4	-1.7	-0.8	-1.0	0.9
Impedance of whole body	0.6	3.1	8.3	0.7	1.9	-0.8	1.4	2.3	2.9	-1.1	2.8	2.3	2.4	1.3	1.9	-0.8	1.5	1.3	1.8	1.8
Schizophrenia vs Biploar Disorder	0.5	0.6	2.6	-0.1	0.6	-1.3	0.1	1.0	1.1	-0.4	0.2	0.6	-0.7	0.5	0.7	-1.1	0.6	1.0	1.6	0.3
Age at First Birth	0.5	0.7	6.6	-0.1	0.4	0.8	-0.6	-0.0	-0.2	-0.7	0.1	0.1	1.2	-0.1	-0.9	-0.8	-0.1	-2.6	-0.8	-0.1
Crohns Disease (2012)	0.5	0.8	3.5	-1.6	-0.5	-1.1	-0.7	-0.8	-0.1	-0.7	-0.9	-0.9	-0.1	-1.1	-1.2	-1.9	-0.1	-0.1	-0.4	0.4
Rheumatoid Arthritis	0.5	0.7	2.7	-0.5	0.9	-0.5	-0.4	0.7	0.4	-1.6	0.9	0.4	-0.1	0.0	1.6	-1.1	-0.8	-0.1	0.6	1.3
Triglycerides	0.5	0.8	3.0	1.1	0.8	1.0	0.9	0.5	-0.4	1.7	0.5	0.5	0.4	0.9	0.1	1.4	0.9	-0.2	-0.0	-1.7
Blood White Count	0.5	3.9	15.3	0.5	0.8	-0.8	2.5	2.1	2.6	3.5	-0.4	2.1	-0.7	1.1	0.4	0.4	3.9	2.0	3.6	1.3
Hypothyroidism (self reported)	0.5	1.1	4.1	1.5	0.8	-0.2	1.2	1.0	0.7	0.9	0.4	1.0	-0.6	1.3	0.6	2.0	1.1	0.0	1.6	-1.3
Average weekly spirits intake	0.5	0.7	3.3	-0.7	-0.4	-1.4	-0.5	-0.4	-1.0	-1.8	-1.4	-0.2	-0.3	-0.6	0.9	-0.4	-0.9	-0.0	-0.6	0.5
Hearing difficulty/problems: Yes	0.5	0.7	4.2	0.5	-0.3	0.8	0.0	-0.6	-1.1	-0.4	-2.0	-0.7	-0.9	0.2	-0.2	1.5	-0.4	0.0	-0.9	-1.1
Medication for hormone replacement therapy	0.5	0.5	1.9	-0.6	-0.6	-1.1	-0.6	-0.3	0.4	-1.4	0.8	-0.2	-0.8	-0.4	-1.0	-0.4	-0.5	-1.3	0.2	0.8
Townsend deprivation index at recruitment	0.5	0.8	4.1	0.6	0.3	0.3	-0.3	-0.1	-0.9	1.5	-1.8	0.1	0.1	0.4	-0.2	1.1	-0.1	-2.0	-1.1	-0.1
Average weekly fortified wine intake	0.5	0.5	2.6	-0.4	-0.2	-0.0	-0.4	-0.2	-0.7	-1.2	-0.4	-0.5	0.2	-0.1	-0.5	-1.0	-1.1	-1.0	-0.9	1.6
Serious illness, injury or assault to yourself	0.5	0.6	2.0	1.0	0.9	-0.5	0.6	1.3	0.8	0.2	0.8	1.4	-0.4	1.1	-1.1	0.4	0.2	0.1	0.2	-0.6
High blood pressure	0.5	1.4	4.0	1.5	0.9	0.7	0.9	1.3	0.8	1.7	0.2	1.3	0.4	1.7	0.8	1.6	1.4	0.2	1.6	-2.0
Hair/balding pattern: Pattern 2	0.5	0.6	2.5	-1.1	-0.5	-1.0	-0.9	-0.4	-0.6	-0.9	-0.7	-0.4	-0.5	-1.0	-0.4	-1.6	-0.8	-0.9	0.6	0.5
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	3.8	-1.3	-0.2	-0.5	-0.7	-0.7	-0.5	-0.1	-0.7	-0.5	0.2	-1.2	-0.4	-2.0	-0.3	-1.4	-0.7	1.0
Noisy workplace	0.5	0.7	2.6	-0.2	-0.9	-0.7	-0.6	-0.6	-0.3	-1.4	-1.6	-0.5	-0.1	-0.2	-0.7	-0.2	-0.6	-1.0	-1.6	0.4
Pulse rate, automated reading	0.5	1.5	4.6	1.1	2.1	1.9	1.6	1.1	0.5	1.2	1.0	1.0	1.9	1.1	0.9	0.3	0.5	0.7	-0.7	-1.6
Alcohol intake frequency.	0.5	1.2	5.6	1.3	1.4	1.7	0.5	0.6	-0.1	0.9	0.6	0.6	-0.2	1.3	0.7	2.3	0.5	-0.7	0.4	-2.4
Commuting to job workplace: Car/motor vehicle	0.5	0.6	3.9	-0.2	-0.4	-1.6	0.2	0.2	0.7	-1.0	-0.2	0.0	-2.0	-0.1	0.1	-0.5	-0.3	-0.0	0.9	1.1
Knee pain experienced in last month	0.5	0.8	2.9	-0.1	-0.5	0.9	-0.1	-0.9	-0.9	0.6	-1.3	-0.8	-1.5	-0.4	-0.6	0.7	-0.2	0.0	-1.7	-1.6
Illnesses of siblings: Diabetes	0.5	0.6	3.8	-0.4	-0.6	0.5	0.3	-0.8	-1.0	0.9	-2.0	-1.1	-0.6	-0.4	-0.7	0.3	0.2	0.4	-1.1	0.7
Osteoporosis (self-reported)	0.5	0.6	2.0	0.2	-1.2	-0.3	-0.4	-0.8	-0.6	0.2	0.3	-0.4	-1.0	-0.3	-1.4	1.3	-0.5	-0.9	-0.1	-1.3
Smoking status: Current	0.5	0.8	6.0	-0.3	-0.9	-0.9	-0.3	-0.8	-0.4	-0.7	-1.1	-0.6	-2.5	-0.6	-0.9	0.3	-0.4	-0.8	-0.5	1.0
Guilty feelings	0.5	0.8	3.2	0.0	-1.1	-0.6	-0.5	-1.3	-0.7	-0.0	-0.4	-1.1	-1.2	-0.6	-1.5	0.6	0.5	0.1	0.8	-1.8
Irritability	0.5	0.8	3.4	-0.6	-0.6	0.2	-1.2	-1.1	-1.5	0.0	-0.7	-1.3	-0.8	-0.8	-1.2	-0.4	-0.3	-1.9	-0.7	-0.3
Cholesterol lowering medication	0.5	0.8	2.4	0.9	0.9	-0.7	0.9	0.9	0.6	0.6	0.7	0.9	-0.2	0.8	1.1	0.4	0.6	0.8	1.6	1.5
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.1	1.2	1.1	1.0	0.7	0.9	-0.0	0.1	0.5	0.9	1.1	1.3	0.4	1.4	0.4	0.2	0.1	-0.3
Alcohol drinker status: Previous	0.5	0.6	2.4	0.6	0.7	1.5	0.2	-0.0	0.1	-0.0	1.4	0.0	1.1	0.4	0.5	1.1	-0.1	0.2	0.7	-1.5
HbA1C	0.4	0.5	2.2	-0.2	-1.2	-0.2	0.2	-0.6	0.3	1.5	-0.2	-0.7	-0.8	-0.4	-0.7	0.5	0.7	1.3	0.4	0.0
Blood Platelet Count	0.4	4.6	10.6	2.8	3.3	3.1	2.4	2.6	1.8	0.7	1.3	2.5	1.4	2.7	1.6	2.3	1.2	1.3	0.1	-3.2
Cardiovascular Disease	0.4	1.2	5.8	1.4	-0.1	0.5	0.6	0.6	0.1	1.0	-0.1	0.7	0.2	1.3	-0.1	2.4	1.2	1.1	1.2	-2.4
Medication: Co-codamol	0.4	0.5	1.9	0.9	0.5	-0.1	0.6	0.3	-0.0	-0.9	-0.3	-0.0	-1.4	0.8	-0.7	1.1	-0.0	0.5	0.5	-1.0
Diabetes (father)	0.4	0.5	2.5	0.9	0.3	0.8	0.4	0.6	0.6	0.2	1.6	0.8	-0.0	0.7	0.0	1.2	0.3	0.4	-0.2	-1.3
Maternal smoking around birth	0.4	0.5	1.2	0.8	1.1	0.2	0.8	1.1	0.4	-0.2	0.2	1.0	-0.1	0.9	0.8	0.7	0.8	-1.0	0.2	-0.8
Multivitamins +/- minerals	0.4	0.5	4.0	-0.6	-0.0	0.6	-0.4	-0.2	-0.1	0.1	0.7	-0.1	2.0	-0.6	1.1	-1.0	-0.1	0.7	-0.5	0.3
High blood pressure (mother)	0.4	0.6	2.1	-0.5	-0.8	-1.3	-1.1	-0.4	-0.3	-0.5	0.6	-0.3	-1.0	-0.7	-1.5	-0.7	-0.8	-0.8	-0.2	0.8
Alcohol usually taken with meals	0.4	0.6	3.7	-0.6	-1.4	-1.3	-0.2	-0.6	0.1	-0.6	-0.4	-0.3	-0.7	-0.6	-0.8	-0.6	0.0	0.5	-0.5	1.9
Diabetes (self-reported)	0.4	0.6	3.6	1.0	0.1	0.2	0.1	0.5	-0.3	1.0	0.8	0.4	-0.7	1.0	0.6	1.9	-0.3	-1.0	0.5	-1.2
Father’s age at death	0.4	0.5	2.1	0.7	-0.2	0.6	0.9	0.1	0.9	-1.4	1.1	0.4	0.8	0.3	1.4	0.3	-0.3	0.0	0.2	-0.7
Impedance of arm (left)	0.4	1.9	6.0	0.6	1.6	-0.4	1.0	1.6	2.0	-1.2	2.4	1.6	2.2	0.9	1.8	-0.5	0.6	1.6	1.1	1.1
Tense / ‘highly strung’	0.4	0.6	2.6	-0.2	-0.6	0.6	-1.0	-1.0	-1.6	-1.0	-0.1	-1.1	-0.4	-0.5	0.3	0.3	-1.4	0.6	-0.8	-0.8
Pulse wave reflection index	0.4	0.5	3.1	-0.3	-1.3	-1.8	-0.6	-0.7	0.1	-0.1	0.5	-0.7	-0.8	-0.3	-0.1	0.3	0.5	-0.1	1.1	0.7
Headache pain in last month	0.4	0.7	2.2	0.4	1.2	0.1	1.4	1.2	1.5	0.7	0.1	0.8	-0.6	0.9	0.0	0.2	0.9	0.8	0.8	0.5
Comparative body size at age 10	0.4	1.0	2.3	-1.2	-1.5	-1.0	-1.1	-1.4	-0.8	0.1	-0.5	-1.4	-1.5	-1.2	-0.9	-0.4	-0.8	-1.3	0.2	0.3
Pulse wave peak to peak time	0.4	0.4	2.4	-1.0	0.1	0.0	-0.5	0.0	0.1	-1.0	-0.2	-0.2	-0.3	-0.6	-0.3	-1.5	-1.1	-0.3	-0.7	0.9
Migraine (self-reported)	0.4	0.6	3.0	-1.2	0.1	-0.5	-0.5	0.0	0.4	-0.1	0.5	-0.1	0.0	-0.7	-0.5	-1.6	0.1	1.1	-0.4	1.7
Had major operations	0.4	0.4	2.0	0.5	0.8	1.4	0.6	0.6	0.4	-0.2	0.6	0.4	0.3	0.8	0.3	0.5	-0.3	1.0	-0.6	-0.8
Loneliness, isolation	0.4	0.5	1.6	0.1	-0.3	0.4	-1.0	-0.8	-1.1	-0.6	-0.6	-0.8	-0.7	-0.2	-0.7	0.5	-0.7	-0.4	-1.3	-1.1
Average weekly champagne plus white wine intake	0.4	0.5	3.0	-0.2	0.3	1.7	0.4	0.1	0.9	0.8	1.1	-0.1	1.1	0.1	0.6	-0.6	0.5	0.2	0.6	0.9
Hearing aid user	0.4	0.5	1.5	0.6	1.2	0.9	0.6	1.0	1.0	0.1	0.5	0.9	-0.2	1.0	0.6	0.6	0.5	0.1	0.5	-0.1
Vascular/heart problems diagnosed by doctor	0.4	1.2	3.6	-1.4	-0.6	-0.4	-0.7	-1.1	-0.5	-1.3	0.2	-1.2	-0.2	-1.6	-0.7	-1.5	-1.3	-0.3	-1.6	1.9
Pain experienced in last month	0.4	0.7	2.8	-0.1	0.3	-0.7	0.1	0.7	0.4	-1.7	0.6	0.6	1.2	-0.0	1.3	-1.3	-0.1	-0.4	1.1	1.3
Alzheimer’s Disease (in father)	0.3	0.4	2.1	0.9	0.3	-0.0	0.4	0.6	0.8	-0.8	0.3	0.5	1.4	0.7	0.1	0.4	0.4	-0.2	-0.7	-0.5
Prostate Cancer	0.3	0.5	1.5	-0.5	0.6	0.1	-0.3	0.0	-0.5	-0.6	1.2	0.3	-0.1	-0.5	0.4	-1.2	-0.8	-1.1	-0.9	0.9
Type 2 Diabetes (T2D) (2012)	0.3	0.3	2.3	-0.2	-0.5	-0.5	-0.4	-0.4	-0.0	-1.5	-0.6	-0.5	0.3	-0.5	-0.2	-0.6	-0.6	-0.7	-0.1	0.2
Ulcerative Colitis	0.3	0.5	1.5	1.1	0.3	-0.6	0.6	0.6	0.0	0.2	0.1	0.3	0.0	1.0	-0.1	1.2	0.3	0.8	1.2	-1.2
Heel T-Score	0.3	2.1	5.8	0.9	0.8	0.4	1.9	1.8	2.1	1.6	1.9	1.9	1.1	1.2	0.1	-0.7	1.7	1.0	2.4	1.5
Number of treatments/medications taken	0.3	0.5	1.5	0.8	0.6	0.8	0.4	0.6	0.4	0.0	-0.1	0.7	-0.0	0.9	0.4	1.2	0.5	1.2	0.5	-1.1
Sensitivity / hurt feelings	0.3	0.6	2.7	0.3	-0.9	0.7	-0.2	-0.9	-0.7	-0.6	-0.3	-0.9	-1.6	-0.3	0.0	1.1	-0.7	0.4	0.2	-1.2
Vitamin and mineral supplements	0.3	0.4	1.8	0.1	-0.2	-1.4	-0.1	0.2	-0.1	-0.5	-1.2	-0.1	-1.4	0.3	-1.4	0.5	-0.2	-0.5	-0.1	0.4
Medication: Metformin	0.3	0.4	2.4	0.6	0.0	-0.1	-0.2	0.3	-0.3	1.5	-0.3	0.1	-0.7	0.6	0.4	1.3	-0.0	-1.2	0.6	-0.5
Diabetes (mother)	0.3	0.3	1.7	-0.4	-0.4	-0.9	-0.4	-0.7	-0.3	-0.2	-0.7	-0.6	-1.3	-0.6	-0.3	-0.2	-0.9	0.1	-0.1	0.1
Chronic bronchitis/emphysema (father)	0.3	0.4	1.9	0.2	0.3	0.1	0.3	0.1	0.9	-0.4	0.7	0.1	-0.5	0.3	-0.3	0.8	0.2	0.7	1.4	-1.4
Nervous feelings	0.3	0.6	2.6	1.3	0.1	0.5	0.9	0.5	0.1	0.1	1.1	0.4	-0.3	1.0	0.7	1.6	0.7	0.5	0.7	-1.1
Mouth/teeth dental problems: Dentures	0.3	0.5	1.5	-0.6	-0.4	-0.5	-1.1	-0.5	-0.7	-1.0	-1.0	-0.8	-0.7	-0.5	0.9	-0.5	-1.2	-0.5	-0.2	0.9
Depression (self-reported)	0.3	0.3	1.7	0.2	0.4	-0.7	-0.4	0.6	0.7	-1.0	0.3	0.6	-0.3	0.5	0.0	-0.0	0.3	0.5	1.3	0.4
Exposure to tobacco smoke at home	0.3	0.4	1.1	0.7	0.6	1.0	0.4	-0.1	-0.7	0.4	-0.8	-0.1	0.7	0.2	-1.0	0.8	-0.0	-0.3	-0.4	-1.0
Breastfed as a baby	0.3	0.4	2.5	0.3	0.6	0.7	0.3	0.1	-0.7	0.2	-0.4	-0.0	-0.8	0.2	1.6	0.9	-0.2	1.0	-0.0	0.2
Chronic bronchitis/emphysema (mother)	0.3	0.4	2.7	-0.5	0.4	-0.3	-0.7	-0.3	-0.6	-0.0	-1.5	-0.3	0.1	-0.2	0.8	-0.2	-0.2	-1.6	0.0	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	2.4	0.3	-0.1	0.2	-0.4	0.0	-0.3	0.0	-0.6	0.1	1.3	0.4	0.2	0.7	0.5	0.0	-0.1	-1.5
Medication: Omeprazole	0.3	0.4	1.2	0.9	0.9	0.6	0.4	0.7	-0.1	-0.6	0.5	0.7	1.0	1.0	0.7	1.1	-0.2	0.1	-0.2	0.1
Suffer from ‘nerves’	0.3	0.5	2.0	0.9	0.1	0.8	0.8	0.3	0.0	1.1	-0.3	0.3	-0.0	0.7	-1.1	1.4	1.1	-0.1	-0.0	-0.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.4	-0.0	-0.7	0.0	-0.2	-0.5	-0.4	-0.4	0.4	-0.3	-0.6	-0.2	1.2	0.8	-0.3	1.1	0.7	0.7
Medication: Aspirin	0.3	0.4	1.5	0.8	0.8	0.9	0.7	0.9	0.7	-0.1	-0.2	0.6	0.7	1.0	0.6	0.6	0.3	1.2	0.4	-0.1
Ever had bowel cancer screening	0.3	0.4	1.9	0.6	-0.3	1.4	-0.1	-0.3	-1.1	0.5	-0.1	0.2	0.6	0.2	0.1	1.2	-0.0	-0.1	-0.5	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	5.7	0.1	-0.2	0.5	0.7	-0.2	0.2	-0.2	0.5	-0.2	0.3	-0.1	0.7	0.2	0.8	2.4	0.8	-0.5
Medication for cholesterol	0.3	0.5	1.7	-0.7	-0.5	1.3	-0.6	-0.8	-0.9	0.8	-0.2	-0.6	0.9	-0.9	0.1	-0.1	-0.4	0.8	-1.0	-0.5
Medication: Gliclazide	0.3	0.3	2.6	-0.4	-0.6	-0.3	-0.7	0.0	-0.5	0.2	-0.1	-0.0	-0.7	-0.2	1.2	-0.0	-0.5	0.0	0.2	1.6
Eye problems/disorders: Glaucoma	0.3	0.4	5.1	0.0	-0.1	-0.6	-0.2	-0.0	0.2	-2.3	-0.1	-0.1	-1.0	0.1	-0.0	-0.2	-0.4	-0.2	0.2	-0.6
Medication: Blood pressure	0.3	0.6	2.0	1.0	0.8	-0.5	0.9	1.2	1.1	0.7	0.1	1.0	-0.1	1.4	-0.1	0.4	1.1	-0.3	0.7	-0.2
Fractured/broken bones in last 5 years	0.3	0.4	2.1	0.5	0.3	0.4	-0.3	0.3	-0.1	-1.1	0.4	0.2	0.7	0.6	0.0	0.4	-1.3	0.7	-1.4	-0.4
Unable to work because of sickness or disability	0.3	0.4	2.7	-0.7	-0.4	-0.7	-0.1	-0.2	-0.1	-0.5	-1.2	-0.3	-1.7	-0.5	-0.1	-0.3	0.4	0.1	0.5	0.4
Worry (Nagel 2018)	0.2	0.4	2.6	1.0	0.0	0.9	0.3	-0.1	-0.7	-0.2	-0.2	-0.2	-1.1	0.6	-0.2	1.6	0.2	-0.1	-0.3	-1.1
Breast Cancer	0.2	0.5	1.9	-0.6	-0.5	0.2	-1.4	-0.7	-1.2	-0.8	0.8	-0.7	0.5	-0.6	0.0	0.0	-1.1	-0.2	-0.5	0.1
HDL Cholesterol	0.2	0.3	1.6	0.3	0.3	0.3	0.1	0.4	0.5	-0.0	0.9	0.4	0.5	0.5	1.1	0.4	0.0	1.2	0.4	0.1
Blood Eosinophil Count	0.2	1.2	4.2	-1.3	-0.9	-0.9	-0.7	-1.1	-1.2	0.9	-2.0	-0.8	-0.7	-1.4	-1.9	-0.7	0.2	-1.4	-0.4	0.1
Hand grip strength (left)	0.2	0.5	2.2	-0.4	-0.4	-1.0	0.0	0.2	0.4	0.2	-0.2	-0.1	-0.7	-0.2	-1.5	-1.4	0.7	0.8	-0.9	1.1
Angina	0.2	0.3	1.8	-0.1	0.3	-0.4	-0.1	0.2	-0.4	-1.2	-1.4	-0.0	0.0	-0.0	0.2	0.2	-0.3	0.4	0.0	-1.0
Hand grip strength (right)	0.2	0.6	3.4	-1.0	-0.6	-0.7	-0.2	-0.2	0.4	0.1	-0.1	-0.3	-0.8	-0.7	-1.3	-1.9	0.4	0.9	-0.4	1.4
Relative age voice broke	0.2	0.3	2.4	-0.0	0.5	0.6	0.1	0.2	0.5	1.6	0.5	0.2	0.1	0.1	-0.7	-0.2	0.6	0.0	-0.0	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.6	2.5	-0.4	-0.1	-1.3	0.1	0.4	0.6	0.5	0.6	0.3	0.4	-0.1	-0.7	-1.3	0.6	0.2	1.6	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.5	0.0	0.4	-0.7	0.3	0.8	0.7	0.5	0.6	0.7	1.2	0.4	-0.5	-1.0	0.8	-0.2	1.2	0.4
Pain all over the body in last month	0.2	0.2	0.5	-0.6	-0.4	-0.3	-0.4	-0.3	-0.3	0.3	-0.7	-0.3	-0.7	-0.4	-0.7	-0.6	-0.0	0.3	0.0	0.5
Hair/balding pattern: Pattern 3	0.2	0.2	1.4	0.2	0.1	1.2	0.1	-0.1	-0.6	1.0	-0.2	-0.1	0.2	0.1	0.7	0.6	0.4	0.3	-0.6	0.0
Pulse wave Arterial Stiffness index	0.2	0.2	1.3	0.6	-0.4	-0.3	-0.0	-0.5	-0.5	0.6	-0.0	-0.2	-0.1	0.1	-0.0	1.1	0.7	0.1	0.4	-0.5
Peak expiratory flow (PEF)	0.2	0.5	2.2	-0.6	0.2	-1.0	0.3	0.2	0.4	-0.6	0.1	0.1	1.5	-0.2	0.2	-1.3	0.0	0.0	-0.6	1.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.3	0.8	0.2	-0.4	0.3	0.5	0.3	-0.6	1.1	0.5	-0.6	0.6	0.5	1.1	-0.1	-0.2	1.1	-0.6
High blood pressure (siblings)	0.2	0.2	1.3	-0.0	-1.1	-0.4	0.1	-0.6	0.0	-0.2	-0.6	-0.3	-1.1	-0.4	0.3	0.2	-0.1	0.2	0.2	0.4
Angina (self-reported)	0.2	0.3	2.2	0.0	0.3	-0.2	0.1	0.2	-0.3	-1.0	-1.5	0.1	0.2	0.1	0.5	0.3	-0.1	0.4	-0.0	-1.0
Medication: Allopurinol	0.2	0.3	1.8	-0.6	-0.1	-0.6	-0.1	0.2	0.4	0.4	-0.4	0.4	1.3	-0.4	-0.5	-1.3	0.5	0.6	-0.3	-0.0
Number of full sisters	0.2	0.2	0.8	0.5	-0.1	-0.7	0.5	-0.1	-0.6	0.3	-0.8	0.2	-0.9	0.3	-0.0	0.8	0.1	-0.4	-0.5	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	1.2	-0.4	0.1	-0.7	-0.7	-0.2	-0.6	-0.1	0.3	-0.3	0.5	-0.2	-0.8	-0.5	-0.7	0.0	-0.6	1.1
Illnesses of father: Heart disease	0.2	0.2	1.6	0.1	0.7	0.6	0.3	0.2	-0.4	0.4	-0.4	0.2	-0.3	0.1	1.3	-0.1	0.1	0.8	0.2	-0.4
Average weekly red wine intake	0.2	0.3	1.7	0.3	-0.2	-0.5	0.2	0.1	0.1	-0.2	0.4	0.2	-1.3	0.2	-1.3	-0.2	0.3	-0.0	0.6	-0.3
Number of self-reported non-cancer illnesses	0.2	0.3	2.8	0.0	0.1	-0.3	-0.5	-0.0	-0.3	-0.3	-0.9	0.1	-1.7	0.2	0.6	0.4	-0.6	0.2	0.4	-0.1
Mother’s age at death	0.2	0.2	0.6	0.4	-0.7	0.0	-0.3	-0.6	-0.7	-0.1	0.5	-0.5	-0.1	-0.2	-0.2	0.7	-0.8	-0.1	-0.3	-0.8
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.0	0.7	0.6	0.2	-0.1	0.7	0.1	-0.3	-0.4	0.4	0.5	0.8	0.2	0.5	-0.0	-0.4	-0.6	-1.0
High cholesterol (Self-reported)	0.2	0.3	1.9	0.3	0.7	0.3	0.2	0.2	-0.8	1.4	-1.1	0.1	0.5	0.3	0.0	0.5	0.5	0.4	0.0	0.5
Medication: Atorvastatin	0.2	0.2	0.9	-0.7	-0.2	-0.6	-0.6	0.1	0.2	0.3	-0.1	0.1	0.3	-0.3	-0.8	-1.0	-0.3	0.1	0.4	-0.2
Diastolic blood pressure, automated reading	0.2	0.7	3.2	-0.9	-0.4	-1.5	-0.2	-0.5	-0.2	-0.8	-1.2	-0.7	-1.8	-0.7	-0.4	-0.9	-0.5	-0.9	0.1	0.3
Basal cell carcinoma (self-reported)	0.2	0.3	1.3	0.5	0.5	1.2	0.1	0.4	0.3	0.3	-0.0	-0.1	0.9	0.8	-0.2	0.6	0.1	-0.3	-0.9	-0.2
Ulcerative Colitis (UC)	0.1	0.3	1.7	-0.1	-0.3	-1.3	-0.2	-0.1	-0.4	0.3	-0.8	-0.2	-0.6	-0.1	-0.3	-0.4	-0.0	0.2	1.0	-0.6
Blood Red Count	0.1	1.3	3.5	0.9	0.7	1.4	1.9	0.9	1.2	1.7	0.8	0.8	-0.3	1.1	0.6	0.7	1.6	1.4	1.8	0.8
Lung FEV1/FVC ratio	0.1	0.7	2.4	-0.2	-0.7	-1.6	0.1	-0.7	-0.4	-1.6	-0.7	-0.7	-0.4	-0.6	-0.6	-0.2	-0.6	-1.4	-1.0	1.3
Hair Pigment	0.1	2.3	7.1	1.5	1.3	1.5	1.3	1.2	1.6	2.4	0.9	1.3	-0.0	1.5	1.5	1.5	2.5	0.5	2.7	-1.5
Tanning	0.1	0.9	5.2	0.2	0.7	0.5	0.2	1.0	1.3	-2.3	0.5	0.9	1.1	0.6	-0.1	-1.2	-0.8	1.4	-1.0	1.0
Pack years adult smoking proportion	0.1	0.2	1.2	-0.2	-0.2	-0.1	-0.1	0.0	0.2	-0.5	-0.8	-0.1	-1.0	-0.2	0.6	0.3	-0.2	-0.4	0.1	1.1
Had menopause	0.1	0.1	1.0	-0.2	0.0	-0.0	-0.0	-0.3	-0.0	0.1	-0.2	-0.4	-0.4	-0.2	0.0	-0.3	0.2	-1.0	0.6	0.5
Illnesses of siblings	0.1	0.2	1.0	-0.3	0.4	-0.2	-0.2	0.3	0.1	-0.2	1.0	0.1	0.6	-0.2	-0.6	-0.7	0.0	-0.1	0.2	0.6
Birth weight of first child	0.1	0.2	1.7	0.1	0.0	0.3	0.3	-0.0	0.2	-0.7	0.6	-0.1	0.7	-0.1	0.8	-0.2	-0.4	-1.3	-0.5	0.3
Breast cancer (self-reported)	0.1	0.1	0.9	-0.0	0.1	-0.3	0.4	-0.1	0.1	0.7	0.4	0.0	-0.3	-0.1	0.2	-0.0	0.0	0.8	0.1	0.9
Pack years of smoking	0.1	0.2	1.3	-0.3	-0.1	0.1	-0.1	0.1	0.2	-0.4	-0.6	0.0	-0.4	-0.2	1.0	0.2	-0.1	-0.3	0.2	1.1

Hub : Genes

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Models

Trait associations