Best TWAS P=1.99e-14 · Best GWAS P=3.07e-09 conditioned to 0.0383
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | FKBP2 | 0.27 | 0.06 | lasso | 6 | 0.14 | 2.1e-05 | 3.4 | 5.7 | 1.0e-08 | 0.42 | 0.22 | 0.19 | FALSE |
| 2 | GTEx | Liver | PPP1R14B | 0.22 | -0.01 | enet | 24 | 0.01 | 1.3e-01 | 5.3 | 7.7 | 2.0e-14 | 0.55 | 0.03 | 0.42 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | MARK2 | 0.09 | 0.02 | bslmm | 324 | 0.03 | 8.0e-05 | 3.0 | 5.5 | 3.1e-08 | 0.49 | 0.05 | 0.93 | FALSE |