[Hub]/) : Traits : Bipolar Disorder or Schizophrenia :

chr11:65,405,300-67,324,933

Best TWAS P=6.98e-10 · Best GWAS P=2.92e-09 conditioned to 0.744

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RIN1 0.07 0.04 bslmm 304 0.04 8.7e-06 -3.3 -5.2 2.4e-07 -0.52 0.87 0.07 FALSE
2 GTEx Adipose Subcutaneous CTD-3074O7.5 0.11 0.03 lasso 4 0.02 4.2e-03 5.9 6.2 7.0e-10 0.95 0.01 0.97 TRUE
3 GTEx Artery Tibial CTD-3074O7.12 0.08 0.01 enet 15 0.03 2.6e-03 4.9 5.3 1.3e-07 0.81 0.05 0.92 FALSE
4 GTEx Brain Cerebellum CTD-3074O7.12 0.15 0.12 enet 14 0.08 2.5e-03 -3.7 5.1 2.8e-07 0.61 0.09 0.27 FALSE
5 GTEx Breast Mammary Tissue CTD-3074O7.12 0.13 0.05 enet 9 0.05 1.4e-03 -3.6 5.1 3.1e-07 0.62 0.13 0.60 FALSE
6 GTEx Cells EBV-transformed lymphocytes CCS 0.21 0.24 enet 11 0.21 2.0e-07 -5.2 5.3 1.3e-07 0.86 0.12 0.87 FALSE
7 GTEx Esophagus Mucosa CTD-3074O7.12 0.10 0.04 lasso 7 0.04 1.9e-03 5.9 5.2 2.2e-07 0.89 0.02 0.97 FALSE
8 GTEx Nerve Tibial CTSF 0.06 0.01 lasso 3 0.01 7.1e-02 5.8 -5.4 8.7e-08 -0.90 0.01 0.96 FALSE
9 GTEx Spleen CCS 0.20 0.19 lasso 4 0.22 3.1e-06 5.9 5.9 2.9e-09 1.00 0.01 0.98 FALSE
10 GTEx Testis BBS1 0.07 0.10 lasso 2 0.07 6.3e-04 5.9 -5.8 6.8e-09 -0.96 0.01 0.91 FALSE
11 GTEx Thyroid CTSF 0.06 0.01 enet 13 0.03 2.3e-03 5.8 -5.7 1.5e-08 -0.94 0.01 0.98 FALSE
12 GTEx Thyroid CTD-3074O7.5 0.37 0.01 lasso 8 0.01 4.6e-02 5.9 5.9 4.0e-09 0.87 0.01 0.98 FALSE
13 GTEx Thyroid CTD-3074O7.12 0.11 0.07 lasso 3 0.05 8.6e-05 5.8 5.3 9.9e-08 0.92 0.01 0.99 FALSE
14 METSIM Adipose DPP3 0.06 0.04 blup 284 0.04 2.6e-07 -3.7 5.7 1.6e-08 0.74 0.58 0.42 FALSE
15 METSIM Adipose RBM14 0.02 0.00 blup 257 0.01 4.8e-02 -2.5 6.0 2.0e-09 0.74 0.04 0.32 FALSE
16 YFS Blood CCS 0.17 0.27 lasso 11 0.28 6.6e-94 -5.2 5.3 1.2e-07 0.89 0.13 0.87 FALSE
17 YFS Blood LRFN4 0.06 0.05 lasso 5 0.05 7.3e-17 -5.3 5.8 7.6e-09 0.73 0.12 0.88 FALSE
18 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ACTN3 0.09 0.10 lasso 3 0.10 2.7e-11 5.8 -5.6 2.0e-08 -0.96 0.01 0.99 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma LRFN4 0.03 0.04 lasso 4 0.03 1.5e-04 -5.3 5.3 1.5e-07 0.60 0.00 0.97 FALSE
20 The Cancer Genome Atlas Lung Adenocarcinoma ACTN3 0.07 0.08 blup 39 0.07 4.5e-09 4.8 -5.3 1.3e-07 -0.95 0.01 0.99 FALSE
21 The Cancer Genome Atlas Lung Adenocarcinoma BBS1 0.03 0.01 enet 8 0.02 9.9e-04 5.8 5.1 2.8e-07 0.89 0.01 0.96 FALSE
22 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ACTN3 0.05 0.06 blup 39 0.05 3.0e-06 4.9 -5.1 3.0e-07 -0.89 0.03 0.97 FALSE
23 The Cancer Genome Atlas Lung Squamous Cell Carcinoma BBS1 0.02 0.02 blup 48 0.02 1.3e-03 4.8 5.4 8.3e-08 0.86 0.02 0.87 FALSE
24 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CTSF 0.03 0.03 blup 36 0.04 2.9e-05 5.8 -5.4 5.4e-08 -0.95 0.01 0.99 FALSE
25 The Cancer Genome Atlas Pancreatic Adenocarcinoma ACTN3 0.18 0.14 lasso 4 0.14 1.8e-06 5.9 -5.7 1.1e-08 -0.96 0.01 0.99 FALSE
26 The Cancer Genome Atlas Pancreatic Adenocarcinoma SPTBN2 0.11 0.12 lasso 1 0.10 6.3e-05 5.9 -5.9 2.9e-09 -1.00 0.00 0.99 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma LRFN4 0.02 0.02 blup 25 0.01 3.6e-02 -5.3 5.3 1.1e-07 0.68 0.00 0.89 FALSE
28 The Cancer Genome Atlas Soft Tissue Sarcoma ACTN3 0.08 0.06 blup 38 0.07 9.2e-05 5.8 -5.5 3.7e-08 -0.91 0.01 0.97 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma LRFN4 0.03 0.04 lasso 2 0.04 2.2e-04 -5.3 5.3 1.3e-07 0.61 0.00 0.96 FALSE