[Hub]/) : Traits : Bipolar Disorder or Schizophrenia :

chr15:90,718,541-92,135,418

Best TWAS P=4.93e-15 · Best GWAS P=2.5e-13 conditioned to 0.041

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FURIN 0.12 0.14 lasso 2 0.13 1.2e-15 7.3 -7.3 3.3e-13 -1.00 0.00 1.00 FALSE
2 GTEx Adipose Visceral Omentum FES 0.21 0.09 lasso 5 0.05 1.3e-03 -5.7 5.8 5.0e-09 0.60 0.47 0.07 FALSE
3 GTEx Artery Tibial FES 0.16 0.04 lasso 5 0.05 4.8e-05 -5.4 5.2 1.5e-07 0.58 0.56 0.38 FALSE
4 GTEx Cells Transformed fibroblasts FES 0.28 0.17 enet 21 0.20 2.8e-15 -5.7 6.7 2.6e-11 0.77 0.09 0.91 FALSE
5 GTEx Lung FES 0.24 0.07 lasso 6 0.05 5.1e-05 -5.4 6.1 1.1e-09 0.64 0.23 0.73 FALSE
6 GTEx Thyroid FES 0.33 0.19 lasso 6 0.18 4.3e-14 -5.1 5.5 3.4e-08 0.60 0.99 0.01 FALSE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma FES 0.06 0.05 blup 46 0.06 1.9e-05 -6.9 6.4 1.2e-10 0.74 0.01 0.98 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma FES 0.06 0.05 blup 46 0.07 7.4e-14 -5.7 7.8 4.9e-15 0.77 0.05 0.95 TRUE
9 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FES 0.06 0.02 blup 46 0.02 2.4e-02 -5.7 6.6 4.0e-11 0.64 0.01 0.79 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma FES 0.08 0.07 blup 46 0.06 3.4e-04 -7.0 6.6 3.2e-11 0.82 0.00 0.99 FALSE
11 The Cancer Genome Atlas Glioblastoma Multiforme FES 0.12 0.06 enet 6 0.06 5.7e-03 -7.0 6.4 1.9e-10 0.84 0.01 0.88 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FES 0.06 0.03 blup 46 0.05 5.6e-06 -7.0 7.0 3.1e-12 0.71 0.02 0.97 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FES 0.10 0.07 enet 5 0.05 2.8e-06 -6.9 7.1 1.3e-12 0.88 0.01 0.99 FALSE
14 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma HDDC3 0.16 0.10 enet 9 0.12 2.1e-07 -2.9 6.0 1.5e-09 0.56 0.29 0.65 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma FES 0.05 0.04 lasso 2 0.04 2.2e-05 -5.7 6.7 2.4e-11 0.76 0.02 0.97 FALSE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FES 0.08 0.07 enet 7 0.08 4.2e-09 -5.7 6.5 1.1e-10 0.66 0.33 0.67 FALSE
17 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FES 0.13 0.16 lasso 2 0.14 6.1e-10 -5.7 5.5 3.1e-08 0.61 0.80 0.20 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma FES 0.12 0.09 lasso 5 0.08 4.1e-09 -5.7 6.1 1.0e-09 0.65 0.37 0.63 FALSE
19 The Cancer Genome Atlas Stomach Adenocarcinoma FES 0.04 0.01 blup 46 0.02 1.7e-02 -6.9 7.5 5.1e-14 0.63 0.01 0.49 FALSE
20 The Cancer Genome Atlas Testicular Germ Cell Tumors FES 0.32 0.26 lasso 2 0.25 2.0e-09 -5.8 5.8 5.5e-09 0.62 0.70 0.28 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma FES 0.30 0.30 lasso 7 0.32 1.3e-31 -5.8 6.5 8.1e-11 0.72 0.97 0.03 FALSE