Hub : Genes

SETD6

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.3810	0.1180	2.6e-03	0.001	NA	-0.009	NA	-0.001	3.1e-01	NA	6.2e-01	NA	3.4e-01
2	GTEx	Brain Cerebellum	0.3660	0.0730	3.8e-07	0.270	NA	0.203	NA	0.252	1.3e-08	NA	1.2e-06	NA	4.5e-08
3	GTEx	Cells Transformed fibroblasts	0.1350	0.0420	5.5e-05	0.094	NA	0.081	NA	0.091	1.7e-07	NA	1.1e-06	NA	2.3e-07
4	GTEx	Heart Left Ventricle	0.1859	0.0566	1.6e-04	0.113	NA	0.057	NA	0.082	1.4e-06	NA	5.6e-04	NA	3.8e-05
5	GTEx	Muscle Skeletal	0.0917	0.0351	1.5e-03	0.069	NA	0.056	NA	0.053	2.7e-07	NA	3.3e-06	NA	6.7e-06
6	YFS	Blood	0.1428	0.0245	0.0e+00	0.103	0.121	0.120	0.128	0.112	8.9e-32	1.3e-37	3.2e-37	1.1e-39	8.9e-35
7	TCGA	Bladder Urothelial Carcinoma	0.0590	0.0330	1.1e-03	0.023	0.027	0.026	NA	0.028	4.1e-03	2.2e-03	2.8e-03	NA	1.8e-03
8	TCGA	Breast Invasive Carcinoma	0.0242	0.0107	8.1e-06	0.033	0.025	0.027	NA	0.030	1.8e-07	5.1e-06	2.3e-06	NA	7.9e-07
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.1679	0.0570	1.8e-07	0.073	0.043	0.062	NA	0.067	1.3e-08	1.2e-05	1.7e-07	NA	5.0e-08
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0434	0.0255	1.3e-03	0.019	0.018	0.012	NA	0.030	3.0e-03	3.5e-03	1.6e-02	NA	2.5e-04
11	TCGA	Brain Lower Grade Glioma	0.0965	0.0342	1.0e-12	0.095	0.125	0.120	NA	0.119	6.5e-11	5.3e-14	1.6e-13	NA	2.4e-13
12	TCGA	Lung Squamous Cell Carcinoma	0.0383	0.0233	2.4e-03	0.010	0.023	0.008	NA	0.019	2.4e-02	1.0e-03	3.9e-02	NA	3.0e-03
13	TCGA	Ovarian Serous Cystadenocarcinoma	0.0850	0.0460	9.7e-04	0.005	0.026	0.033	NA	0.009	1.3e-01	6.7e-03	2.6e-03	NA	7.2e-02
14	TCGA	Prostate Adenocarcinoma	0.0351	0.0196	1.4e-03	0.036	0.030	0.024	NA	0.028	1.0e-04	3.7e-04	1.2e-03	NA	5.7e-04
15	TCGA	Soft Tissue Sarcoma	0.2680	0.1030	3.5e-04	0.002	0.060	0.053	NA	0.026	2.3e-01	1.9e-04	4.5e-04	NA	1.0e-02
16	TCGA	Thyroid Carcinoma	0.0910	0.0370	7.1e-08	0.080	0.059	0.085	NA	0.094	3.3e-08	1.9e-06	1.2e-08	NA	1.9e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Bipolar Disorder (2018)	3.8	6.0	12.9	-2.8	-2.8	-3.3	-3.5	1.7	-1.1	-0.4	0.0	0.2	-2.2	-3.1	-2.1	-3.6	-3.1	-1.8	-2.9
Bipolar Disorder or Schizophrenia	6.8	16.5	30.3	-1.5	-4.3	-5.4	-5.4	3.1	-3.0	-2.9	0.0	-2.6	-3.7	-4.6	-3.9	-5.5	-5.1	-5.1	-4.3
Depressed Affect (Nagel 2018)	1.0	2.0	6.5	-0.4	-2.4	-1.4	-1.2	2.1	-2.5	-0.7	-1.6	-0.3	-1.3	-0.6	-0.6	-1.3	-1.1	-1.7	-0.8
Depression (Nagel 2018)	3.0	4.6	7.7	-0.3	-2.8	-2.1	-2.6	2.7	-2.6	-1.8	-2.3	-2.0	-2.4	-1.6	-1.4	-1.8	-2.3	-2.3	-1.9
Intelligence (Savage-Jansen 2018)	0.3	0.8	3.0	-0.2	0.7	0.4	1.6	1.5	-0.4	-0.8	0.7	-1.0	0.9	0.7	0.1	0.5	0.8	-1.7	0.7
Neuroticism (Nagel 2018)	1.4	3.3	5.6	-0.6	-2.4	-2.1	-1.4	2.3	-2.4	-0.8	-2.2	-0.4	-1.6	-1.5	-1.3	-2.1	-2.1	-1.8	-2.1
Schizophrenia (2018)	5.6	11.6	26.1	0.2	-3.3	-4.2	-4.2	2.1	-3.0	-3.4	0.0	-3.5	-3.0	-3.3	-3.4	-4.2	-4.0	-5.1	-3.2
Schizophrenia vs Biploar Disorder	2.5	3.3	9.5	0.1	-1.8	-1.7	-2.1	0.4	-2.4	-2.7	0.0	-3.1	-1.8	-1.3	-1.9	-1.0	-1.7	-2.2	-1.4
Worry (Nagel 2018)	1.5	3.2	7.5	-0.4	-1.1	-2.0	-1.3	0.5	-1.1	-1.5	-2.2	-1.1	-1.8	-2.1	-2.3	-2.6	-2.6	-0.9	-2.7
Alzheimer’s Disease (in mother)	2.7	3.1	8.8	-0.1	1.7	2.2	1.6	-0.5	1.4	1.2	2.2	0.6	0.7	2.4	1.0	2.0	2.2	3.0	2.5
Alzheimer’s Disease (in father)	1.7	1.8	4.6	0.0	0.5	1.5	0.9	-1.6	0.4	1.5	1.5	1.2	0.2	2.1	1.2	1.2	1.8	1.4	2.1
Alzheimer’s Disease (including proxy)	2.5	3.6	9.6	-0.1	1.5	2.3	1.2	-1.6	1.0	1.5	2.2	0.9	0.1	3.0	1.0	2.0	2.4	3.1	2.9
Crohns Disease (2017)	0.3	0.7	1.7	-0.3	-1.3	-1.1	-0.9	0.9	-0.6	-0.2	-1.1	-0.1	-1.2	-0.9	-0.5	-0.9	-1.1	0.2	-0.9
Irritable Bowel Disease (IBD)	0.7	1.7	5.3	0.1	-2.3	-1.5	-2.0	1.4	-1.4	0.4	-1.6	0.8	-1.2	-1.4	-0.2	-0.9	-1.4	-0.4	-1.2
Ulcerative Colitis (UC)	1.0	1.9	6.8	-0.0	-2.6	-1.3	-2.2	1.7	-1.9	0.9	-1.4	1.3	-0.9	-1.2	0.2	-0.5	-1.0	-1.4	-0.9
Major Depression (MDD)	0.2	0.2	0.8	-0.6	0.2	-0.2	-0.7	0.8	0.1	-0.3	-0.4	0.1	0.3	-0.9	-0.3	-0.3	-0.3	-0.6	-0.1
Reaction Time	0.6	1.1	7.1	-2.7	-1.0	-0.6	-0.5	0.5	-0.4	1.8	-0.6	1.7	-0.7	-0.3	0.7	-0.5	-0.3	-0.3	-0.7
Verbal and Numeric Reasoning (VNR)	0.9	2.2	5.1	-0.6	1.3	1.9	1.9	-0.1	0.5	0.7	2.0	0.5	1.6	2.2	1.3	1.4	2.1	0.2	2.3
Breast Cancer	0.7	1.7	4.1	-0.2	-2.0	-1.6	-1.4	1.6	-1.7	0.1	-1.5	-0.2	-1.7	-0.5	-0.7	-1.0	-1.1	-1.8	-1.3
Ovarian Cancer	1.1	1.5	2.9	0.2	0.5	1.2	1.7	0.1	-1.1	1.3	1.3	1.2	1.5	1.6	1.7	1.4	1.6	-0.3	1.0
Prostate Cancer	0.2	0.3	0.8	-0.5	0.1	0.6	-0.1	-0.2	-0.2	0.5	0.6	0.5	0.5	0.9	0.8	-0.0	0.7	0.1	0.9
Age at First Birth	2.4	3.5	7.0	-0.2	-1.8	-2.2	-2.2	-0.4	-0.3	-1.9	-2.3	-1.7	-2.2	-2.3	-2.6	-1.5	-2.4	-0.2	-2.3
Bipolar Disorder (2011)	2.1	2.0	5.2	-1.5	-2.2	-1.8	-1.9	-0.2	-1.6	0.2	0.0	0.2	0.0	-1.2	-1.1	-2.0	-1.7	-0.4	-2.3
Body Mass Index (BMI) (2010)	1.3	1.8	5.2	1.0	-1.6	-1.8	-1.1	1.1	-1.0	-0.2	0.0	-0.2	-2.3	-0.8	-1.7	-1.7	-1.9	-0.0	-1.8
Coronary Artery Disease (CAD)	2.3	2.7	6.1	1.1	1.5	2.1	2.2	-0.6	0.7	1.3	0.0	1.1	2.1	1.8	2.0	2.5	2.2	0.5	2.0
Crohns Disease (2012)	0.4	0.6	2.4	0.1	-0.2	-0.6	-0.8	0.1	-0.4	-1.3	0.0	-1.5	-0.6	-0.7	-0.8	-0.6	-0.8	-1.0	-0.8
Mean Putamen Volume	1.3	1.5	5.6	-0.6	-2.4	-1.3	-1.4	1.1	-2.3	0.4	-1.1	0.3	-1.6	-0.3	-0.3	-0.6	-0.9	-1.1	-1.3
Fasting Glucose	0.4	0.5	2.9	1.1	0.1	1.1	1.7	-0.3	-0.5	0.3	0.4	0.2	0.7	0.6	0.2	0.3	0.5	0.3	0.4
HbA1C	1.1	1.2	4.9	0.7	-0.6	0.7	-0.0	0.7	-0.4	2.2	0.8	2.1	-0.5	1.5	1.4	1.2	1.1	0.8	0.6
HDL Cholesterol	0.2	0.4	1.0	0.9	-0.8	-0.4	-1.0	-0.5	-0.4	-0.2	-0.5	-0.2	-0.7	-0.3	-0.7	-0.2	-0.7	1.0	-0.7
LDL Cholesterol	0.1	0.2	0.6	0.7	0.1	0.3	-0.1	0.3	0.1	0.2	0.0	0.3	0.7	0.0	0.8	0.7	0.2	0.1	0.2
Lupus	0.4	0.5	3.5	0.7	-0.3	0.3	0.5	0.9	-1.9	0.9	0.3	0.9	0.1	0.7	0.8	0.5	0.5	-0.3	0.2
Neuroticism (2016)	0.8	1.1	5.4	-2.2	-1.7	-0.1	-0.6	0.8	-2.3	-0.1	-0.3	-0.2	0.3	0.4	0.9	0.1	0.1	-1.4	0.5
Primary Biliary Cirrhosis	0.5	0.8	6.2	-1.1	-0.8	-0.7	-0.9	0.7	-0.2	-0.3	-0.7	-0.2	0.1	-0.8	0.1	-0.8	-0.4	-2.5	0.0
Rheumatoid Arthritis	0.7	1.0	3.8	-0.3	1.2	1.1	-0.0	0.4	1.7	0.0	0.0	0.5	1.9	-0.2	1.4	0.5	1.0	-0.3	1.5
Schizophrenia (2014)	5.2	11.6	19.5	-0.6	-3.4	-4.4	-4.1	2.6	-2.9	-3.3	0.0	-3.2	-3.1	-3.8	-3.5	-4.2	-4.4	-3.9	-3.4
Triglycerides	0.2	0.3	2.2	-1.5	0.0	0.1	0.3	0.1	0.0	0.8	0.0	0.8	0.2	0.6	0.4	-0.6	0.4	-0.2	0.7
Type 2 Diabetes (T2D) (2012)	0.8	1.0	6.7	0.7	0.4	1.0	1.2	-2.6	0.6	0.2	0.0	-0.1	0.7	0.9	0.5	0.8	1.0	0.8	1.2
Ulcerative Colitis	1.5	2.1	6.2	0.8	-2.3	-1.7	-2.5	0.9	-1.8	0.5	-1.7	1.2	-1.0	-1.6	-0.2	-0.8	-1.4	-1.0	-1.6
Blood Eosinophil Count	0.2	1.4	5.0	2.2	1.0	1.0	1.1	1.1	1.0	1.6	0.7	1.6	0.9	0.8	1.5	-0.1	1.1	0.1	1.4
Blood Platelet Count	0.9	10.3	30.4	1.4	5.5	3.6	4.1	-2.6	5.3	0.9	3.8	0.5	3.6	2.1	1.8	1.7	3.3	2.1	3.8
Blood Red Count	1.6	15.2	25.2	0.1	-5.0	-4.7	-4.3	0.4	-4.0	-2.4	-4.9	-2.6	-4.9	-2.9	-4.3	-3.8	-4.4	-4.1	-4.7
Blood White Count	0.1	0.8	4.6	-0.5	0.9	0.4	0.9	-1.1	2.1	0.5	0.5	0.5	-0.1	0.5	-0.2	-0.4	0.5	1.4	1.0
Heel T-Score	0.1	0.9	4.0	0.2	0.1	0.3	1.1	-1.9	-0.0	-1.5	0.3	-2.0	-0.8	0.3	-1.0	1.1	0.2	0.3	-0.3
BMI	0.7	4.3	10.8	2.5	-3.3	-1.9	-2.1	2.4	-2.7	1.8	-2.2	1.8	-3.1	-0.1	-0.6	-1.4	-1.1	-1.1	-1.9
Height	0.2	3.6	14.2	-2.2	-3.8	-1.4	-2.5	1.4	-3.4	1.6	-1.3	1.4	-2.7	1.2	0.2	-0.8	-0.2	-1.2	-0.1
Waist Hip Ratio (WHR)	1.2	5.4	10.7	1.3	2.5	2.7	2.7	1.1	2.7	1.5	2.7	1.4	3.3	1.3	2.7	2.3	2.7	1.1	3.2
Systolic Blood Pressure	1.1	5.3	13.6	0.8	-3.7	-2.5	-2.7	0.8	-3.2	-1.0	-2.6	-1.4	-3.0	-0.5	-2.2	-2.6	-1.7	-3.2	-1.5
Smoking Status	0.3	0.6	3.0	-0.3	-1.5	-0.9	-0.6	-0.4	-1.7	0.7	-0.7	0.5	-1.2	0.5	-0.3	-0.2	-0.2	0.0	-0.2
Allergy or Eczema	0.5	1.2	3.3	-0.7	-1.7	-1.3	-1.8	0.3	-1.8	0.2	-1.1	0.1	-1.8	-0.1	-1.0	-0.2	-0.8	-0.9	-1.2
Cardiovascular Disease	0.2	0.8	1.7	0.9	-0.3	-0.9	-1.0	-0.0	-0.5	-1.1	-1.1	-1.3	-0.8	-1.0	-1.0	-0.8	-0.9	-1.2	-0.7
Hypothyroidism (self reported)	0.5	1.2	3.6	0.9	-1.1	-1.1	-1.9	0.1	-0.4	0.1	-1.4	0.4	-1.2	-1.2	-0.9	-1.8	-1.4	0.2	-0.8
Respiratory disease	1.0	2.1	9.7	0.8	-1.2	-1.3	-1.6	2.6	-1.5	-0.9	-1.2	-1.0	-0.2	-1.2	-0.5	-1.5	-0.8	-3.1	-1.1
Type 2 Diabetes (T2D) (2018)	1.7	3.2	8.7	1.7	-2.8	-1.9	-1.7	1.3	-2.5	0.9	-2.1	0.7	-3.0	-0.4	-1.0	-2.1	-1.5	-0.5	-2.1
Lung FEV1/FVC ratio	1.0	4.9	53.2	-2.7	-0.2	-0.5	-1.7	-7.3	1.2	-0.7	-0.9	0.2	0.6	-2.4	-0.8	-1.5	-1.3	0.8	-0.5
Lung FVC	0.3	1.6	3.6	0.5	1.2	-1.1	-1.0	0.7	1.5	-1.9	-1.0	-1.7	-0.2	-1.9	-1.4	-1.6	-1.4	-0.4	-1.2
Neuroticism	0.6	1.5	4.9	-0.6	-1.8	-1.0	-0.5	1.5	-2.0	-0.6	-1.3	-0.4	-0.8	-0.7	-0.7	-1.4	-1.1	-2.2	-1.2
Chronotype (morning person)	0.7	1.5	5.1	1.1	-0.7	-1.6	-0.2	1.6	-0.6	0.6	-1.3	0.8	-0.6	-1.1	-0.2	-1.7	-1.3	-2.3	-1.8
Hair Pigment	0.2	4.8	10.0	0.3	-2.0	-2.8	-1.9	-0.1	-1.6	-1.1	-2.7	-0.6	-3.1	-1.6	-3.2	-2.5	-3.1	-1.1	-3.1
Tanning	0.1	1.1	3.9	0.6	0.8	1.3	0.7	-0.4	1.3	1.0	1.1	0.5	0.7	1.1	0.8	0.4	1.4	1.3	2.0
Hand grip strength (left)	1.6	4.2	11.0	-0.5	-3.0	-2.4	-3.3	-1.5	-1.4	0.5	-2.5	0.8	-3.2	-0.8	-1.9	-3.1	-1.9	-0.0	-1.7
Number of treatments/medications taken	1.2	2.1	5.8	0.7	-2.2	-1.6	-1.5	1.6	-1.7	-0.3	-1.9	-1.0	-2.4	-0.7	-1.0	-1.0	-1.3	-1.1	-1.4
Average weekly spirits intake	1.5	1.8	5.6	2.4	0.9	1.6	1.6	0.4	-0.1	0.5	1.5	-0.2	1.4	1.4	1.3	1.9	1.6	-1.3	0.9
Sensitivity / hurt feelings	0.4	0.7	3.8	-0.7	0.3	0.8	0.3	2.0	0.1	0.0	0.6	0.2	0.9	0.5	0.7	0.0	0.8	-1.2	1.3
Frequency of depressed mood in last 2 weeks	1.3	1.8	5.4	-0.3	-2.1	-1.2	-1.2	2.1	-2.3	-0.7	-1.4	-0.7	-1.2	-0.8	-0.4	-0.7	-1.4	-1.5	-1.3
Hearing difficulty/problems: Yes	0.8	1.2	9.7	-1.1	0.1	0.4	0.5	3.1	-0.6	-0.6	0.5	-0.6	1.4	-0.2	0.6	1.0	0.5	-1.6	0.3
Relative age of first facial hair	0.6	1.3	2.6	-0.9	-0.5	-1.2	-0.4	0.3	0.3	-1.6	-1.1	-1.6	-0.8	-1.3	-1.4	-1.5	-1.5	-1.3	-1.4
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.7	-1.3	-0.4	0.9	-0.3	0.1	-0.9	0.7	0.6	0.3	-0.2	1.2	0.9	1.3	1.0	-0.9	1.1
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.4	-1.1	0.1	-0.3	0.0	-0.9	-0.1	-1.4	-0.5	-1.6	-0.1	-1.0	-0.7	0.4	-0.9	-0.5	-1.1
Ever had hysterectomy (womb removed)	1.6	1.9	4.4	0.4	-0.1	1.4	1.2	-1.6	0.0	1.7	1.3	1.6	0.5	2.1	1.4	1.6	1.9	0.8	1.7
Systolic blood pressure, automated reading	1.1	3.1	11.9	1.2	-3.0	-1.6	-1.7	1.5	-3.4	-0.6	-1.7	-1.0	-1.9	0.1	-1.0	-1.0	-1.0	-2.9	-1.1
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.7	0.8	0.0	0.2	0.2	0.5	-1.1	1.3	0.2	1.2	-0.4	0.6	0.7	0.7	0.3	0.4	-0.8
Angina	2.7	3.6	8.2	2.1	0.6	2.2	1.9	1.0	-0.6	2.1	2.1	1.3	1.5	2.2	2.6	2.9	2.6	-0.5	1.7
Medication for hormone replacement therapy	0.8	0.9	3.4	0.5	-0.6	-1.2	-0.8	-0.9	0.0	-0.7	-1.3	-0.3	-0.5	-1.8	-0.9	-0.5	-1.4	0.1	-1.6
Vitamin and mineral supplements	0.7	1.0	3.0	1.7	-0.5	0.8	-0.1	-1.1	-0.0	1.2	0.7	1.3	0.5	0.9	1.1	0.9	1.2	0.2	1.4
Supplements: Zinc	1.9	2.1	5.4	-1.6	-1.7	-2.1	-1.1	-0.1	-0.9	0.5	-1.9	1.1	-1.5	-1.3	-1.2	-2.3	-1.7	0.2	-1.7
Medication: Co-codamol	0.7	0.8	2.0	-0.6	-0.2	-0.9	-1.4	-0.6	0.2	-0.6	-1.0	-0.3	-0.7	-1.2	-0.9	-1.4	-1.4	-0.0	-1.3
Medication: Metformin	1.4	2.0	4.8	-0.9	-1.7	-1.6	-1.5	2.2	-0.6	-0.3	-1.7	-0.6	-2.2	-0.9	-1.3	-2.0	-1.7	-0.5	-1.1
Diabetes (father)	0.6	0.7	3.0	1.7	-1.1	-1.0	-0.6	0.3	-0.8	0.3	-1.1	0.6	-0.7	-1.1	-0.2	-0.8	-0.8	-0.0	-0.9
Diabetes (mother)	2.2	2.8	7.4	-2.7	-0.6	1.3	0.5	0.9	-2.2	1.5	1.3	1.5	1.1	2.3	2.1	1.7	2.0	-1.3	1.9
Severe depression (siblings)	4.5	5.1	9.2	-1.5	-2.1	-3.0	-2.5	0.6	-1.2	-0.9	-3.0	-0.8	-3.0	-1.9	-2.8	-2.9	-2.9	-0.9	-3.0
Pack years adult smoking proportion	0.9	1.3	4.6	1.2	-0.9	0.4	0.5	0.1	-1.7	2.1	0.3	1.7	-0.7	1.8	1.0	0.5	1.5	0.3	1.0
Impedance of leg (right)	1.1	5.2	16.4	-1.0	3.6	2.6	2.8	-1.5	3.1	-0.8	2.6	-0.8	4.0	0.4	2.2	1.5	1.9	0.1	2.6
Leg fat-free mass (left)	1.1	5.7	18.3	0.6	-4.3	-2.1	-2.7	2.0	-3.1	3.1	-2.4	3.2	-3.9	0.6	-0.4	-1.9	-0.7	-0.3	-1.4
Trunk fat percentage	0.6	2.4	7.3	1.8	-1.1	0.8	0.4	2.7	-1.8	2.1	0.7	1.5	-0.5	2.1	2.0	1.4	1.6	-0.6	1.0
Hand grip strength (right)	0.7	1.8	7.6	-0.5	-2.1	-1.3	-1.7	-1.8	-1.3	0.3	-1.3	-0.0	-2.7	0.5	-1.3	-1.5	-0.6	0.1	-0.7
Townsend deprivation index at recruitment	0.6	0.9	4.0	-0.9	-0.4	-0.2	0.8	1.8	-1.6	-0.9	-0.5	-1.1	0.1	-0.1	-0.6	0.3	0.0	-2.0	-0.3
Current tobacco smoking	0.7	1.1	6.3	-0.6	-1.8	-0.9	-0.7	-0.1	-2.5	1.7	-0.6	1.5	-1.2	0.6	0.0	-0.0	0.1	0.2	-0.3
Average weekly fortified wine intake	0.5	0.6	2.6	-0.5	0.2	0.5	0.3	-1.6	0.9	0.8	0.6	0.9	0.4	0.4	0.6	1.4	0.7	-0.0	0.4
Maternal smoking around birth	0.3	0.4	1.7	-0.8	-1.3	-0.6	-0.8	1.2	-0.6	0.3	-0.4	0.3	-0.5	0.1	0.3	0.2	0.1	-0.8	0.0
Fed-up feelings	0.8	1.5	5.5	-1.1	-1.7	-0.9	-0.9	2.3	-1.7	-0.9	-1.2	-0.6	-0.8	-0.6	-0.5	-1.1	-1.0	-1.7	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	3.5	4.6	7.5	-0.8	-2.4	-2.2	-1.8	2.4	-2.7	-1.8	-2.4	-2.0	-2.1	-1.8	-1.9	-1.9	-2.4	-2.7	-2.4
Relative age voice broke	0.1	0.2	0.6	-0.8	0.2	-0.1	0.6	0.1	0.7	-0.2	-0.1	0.2	0.1	-0.5	-0.0	0.3	-0.2	0.5	-0.2
Taking other prescription medications	1.1	1.6	4.6	0.6	-1.8	-1.2	-1.3	1.9	-2.2	-0.2	-1.5	-0.7	-1.9	-0.6	-0.6	-0.7	-1.0	-1.0	-1.3
Age when periods started (menarche)	0.7	1.7	4.8	-1.6	2.2	1.4	0.9	0.9	1.9	-1.3	1.3	-1.4	1.6	0.4	0.5	1.0	0.8	-0.5	1.3
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	2.5	0.1	-1.0	-0.4	-0.3	-1.2	-0.2	1.5	-0.5	1.6	-1.1	0.4	0.0	-0.5	0.0	0.9	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.6	1.9	-0.6	-0.5	-0.4	-0.2	0.1	-0.5	-0.9	-0.5	-1.2	-1.4	-0.2	-1.0	0.8	-0.6	0.9	-0.7
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.6	0.2	0.1	0.3	1.2	-0.7	-0.8	-0.3	0.4	-1.3	-0.7	1.0	0.0	0.8	0.5	0.2	0.3
Qualifications: CSEs or equivalent	1.1	1.5	5.5	0.8	-1.0	-1.6	-0.8	-0.2	-0.2	-0.6	-1.6	-0.8	-2.2	-0.5	-2.3	-1.5	-1.3	-0.0	-0.7
Serious illness, injury or assault to yourself	1.1	1.3	2.9	-0.6	0.0	1.3	0.1	0.5	-0.3	1.6	1.1	1.6	0.5	1.1	1.6	1.6	1.7	0.7	1.5
High blood pressure	0.2	0.4	1.6	1.2	0.6	0.6	0.2	0.2	0.5	0.4	0.5	-0.1	-0.1	0.5	0.5	1.1	0.6	1.1	0.5
Hayfever, allergic rhinitis or eczema	0.5	1.0	2.6	-1.0	-1.4	-1.1	-1.6	0.1	-1.6	0.4	-1.0	0.5	-1.6	-0.2	-0.6	-0.5	-0.7	-0.9	-1.2
Multivitamins +/- minerals	0.9	1.1	3.2	-1.8	-0.1	-1.1	-0.2	1.0	-0.5	-1.1	-1.0	-1.2	-1.1	-0.9	-1.2	-1.5	-1.3	-0.3	-1.2
Stomach or abdominal pain in last month	0.7	0.8	3.8	0.6	-1.3	-0.6	-0.3	-0.9	-2.0	-0.3	-0.8	-0.2	-0.9	-0.2	-1.0	-0.6	-0.5	-1.4	-1.0
Supplements: Glucosamine	0.4	0.6	1.8	1.3	1.2	0.4	0.7	-0.0	0.1	1.1	0.4	1.2	0.2	0.5	0.7	0.3	0.3	1.1	-0.5
Diverticular disease/diverticulitis (self-reported)	1.5	1.8	5.1	0.5	-1.1	-1.4	-2.2	2.3	-0.9	-0.9	-1.5	-1.0	-1.5	-1.0	-1.0	-0.9	-1.4	-1.3	-1.5
Medication: Atenolol	0.7	0.9	2.0	0.4	0.8	1.3	1.0	0.4	0.8	1.3	1.2	0.7	0.6	1.2	1.3	1.0	1.4	0.3	0.6
Medication: Levothyroxine sodium	0.2	0.3	2.0	1.4	-0.1	0.1	-0.2	0.2	0.9	0.2	-0.0	0.5	0.6	-0.7	0.3	-0.0	-0.3	0.4	0.1
Sitting height	0.5	3.5	13.6	-0.2	-2.5	0.2	-0.6	0.8	-1.8	3.7	0.0	3.6	-2.0	2.7	1.5	0.2	1.5	1.4	1.4
Chronic bronchitis/emphysema (father)	0.4	0.5	1.9	-0.1	-0.6	-0.6	-0.4	0.8	-0.2	-0.2	-0.6	-0.2	-1.4	0.4	-0.9	0.4	-0.7	1.4	-0.4
High blood pressure (mother)	0.3	0.4	1.6	-0.6	-1.3	0.0	-0.3	0.4	-1.2	0.5	0.1	0.2	-0.5	0.8	0.7	0.5	0.7	-0.3	0.8
Body mass index (BMI)	0.9	3.7	10.5	1.6	-3.2	-1.6	-1.9	2.1	-2.8	2.3	-1.8	2.3	-3.0	0.3	-0.2	-1.1	-0.7	-0.8	-1.6
Impedance of leg (left)	1.2	5.9	15.9	-1.7	3.7	2.9	3.0	-1.5	2.5	-1.0	3.0	-1.2	4.0	1.0	2.4	2.1	2.3	0.1	2.9
Leg predicted mass (left)	1.0	5.4	17.3	0.6	-4.2	-2.0	-2.6	2.0	-2.9	3.1	-2.3	3.2	-3.7	0.6	-0.3	-1.9	-0.7	-0.3	-1.3
Trunk fat mass	0.7	2.9	8.2	1.7	-2.2	-0.0	-0.5	2.9	-2.4	2.8	-0.3	2.5	-1.6	1.8	1.6	0.5	1.0	-0.7	0.2
Waist circumference	0.7	2.5	8.1	1.9	-2.2	-0.5	-0.8	2.6	-1.8	2.9	-0.7	2.8	-1.5	0.9	1.0	-0.1	0.5	-0.5	-0.2
Number of incorrect matches in round	3.5	5.8	10.6	-0.9	2.9	2.6	2.8	1.1	2.9	2.3	2.7	2.2	3.2	1.4	3.2	2.3	2.2	2.2	2.1
Past tobacco smoking	0.1	0.2	0.9	-0.2	0.5	0.6	0.9	0.1	0.7	0.0	0.4	0.0	0.3	0.3	-0.3	-0.4	0.2	-0.2	0.1
Alcohol usually taken with meals	1.2	1.9	8.0	1.2	0.3	-1.2	-0.6	1.1	-0.1	-1.3	-1.1	-0.7	1.0	-2.5	-0.6	-0.9	-1.6	-2.8	-2.0
Nervous feelings	0.8	1.5	4.1	-0.9	-1.0	-1.4	-0.2	0.1	-1.5	-0.9	-1.4	-0.8	-1.3	-0.9	-1.7	-1.2	-1.6	-0.6	-2.0
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	2.7	-1.6	-0.9	-0.5	-1.0	0.6	-1.5	-0.5	-0.8	-0.1	-0.5	-0.7	-0.4	-0.6	-0.8	-0.6	-0.6
Hearing difficulty/problems with background noise	0.9	1.4	6.5	-0.9	-0.7	0.5	-0.2	2.1	-2.1	-0.9	0.4	-1.0	1.0	0.4	0.7	1.3	0.5	-2.5	-0.0
Hair/balding pattern: Pattern 2	3.0	3.8	10.1	1.0	-2.5	-2.6	-1.7	-1.3	-2.1	-0.5	-2.5	-0.7	-3.2	-1.1	-2.8	-1.7	-2.1	-0.9	-2.1
Had menopause	0.4	0.5	1.7	0.5	1.0	0.7	0.5	-0.5	0.6	-0.6	0.5	-0.8	1.3	-0.6	0.2	0.9	0.2	-0.9	-0.4
Had other major operations	0.7	0.9	2.5	-0.1	-0.7	0.5	0.1	-0.3	-1.6	1.4	0.4	1.4	0.5	1.1	1.3	0.9	0.8	-1.4	0.1
Forced vital capacity (FVC)	0.2	0.9	4.8	-0.6	-0.4	-1.2	-1.2	0.5	0.4	-0.5	-1.2	-0.0	-0.7	-1.1	-0.6	-2.2	-1.2	-0.7	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	4.3	-0.0	0.7	0.3	0.3	-1.1	1.0	-0.8	0.3	-1.0	-0.9	-0.1	-0.8	1.5	-0.1	2.1	-0.1
Ever unenthusiastic/disinterested for a whole week	2.2	2.7	6.6	-2.6	-2.1	-1.7	-1.9	-0.9	-2.5	-0.2	-1.8	-0.3	-2.3	-0.5	-1.3	-1.5	-1.4	-0.5	-1.8
Qualifications: None of the above	0.9	1.9	5.6	0.9	-0.4	1.4	1.7	1.1	-1.4	1.9	1.4	1.4	0.2	2.4	1.7	1.6	1.4	0.7	0.6
Financial difficulties in last 2 years	0.7	0.9	2.9	1.7	-1.0	-0.0	0.1	0.8	-1.5	1.4	-0.1	1.6	0.0	0.4	0.7	0.7	0.6	-1.4	-0.4
Mouth/teeth dental problems	1.4	2.1	4.5	0.1	-0.8	-1.9	-1.5	-1.8	1.0	-0.3	-1.7	0.2	-1.8	-1.3	-2.1	-2.1	-1.7	1.3	-1.2
Heart attack	0.5	0.6	1.9	-0.5	-1.4	-0.3	-0.6	1.2	-1.3	1.2	-0.3	1.1	-0.3	-0.2	0.5	0.2	0.0	-0.9	-0.2
Allergy	0.7	1.5	3.5	0.4	1.6	1.5	1.8	-0.9	1.9	0.1	1.4	-0.0	1.3	1.0	0.7	0.8	1.1	1.6	1.4
Pain all over the body in last month	0.5	0.5	4.1	-0.6	-0.2	-0.0	-0.3	-0.4	-0.7	-1.0	-0.2	-1.3	0.2	-0.4	-0.0	-0.3	-0.3	-2.0	-0.1
Diabetes (self-reported)	0.4	0.6	1.3	1.1	0.4	1.0	0.7	0.7	0.6	1.0	0.8	0.6	-0.1	1.0	0.9	0.5	0.9	1.1	0.6
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	3.7	-0.9	-0.5	-1.4	-1.4	0.9	-0.1	-0.1	-1.2	1.0	0.2	-1.9	-0.4	-0.9	-1.2	-0.4	-1.1
Medication: Ramipril	2.2	2.8	6.2	-0.5	0.9	2.0	1.4	-0.4	0.9	1.6	2.1	1.1	1.4	2.1	2.1	2.3	2.4	0.9	2.5
Medication: Simvastatin	0.7	1.0	4.7	0.1	-2.0	-0.2	-0.5	1.1	-2.2	-0.4	-0.5	-1.3	-1.3	0.6	-0.3	0.4	-0.2	-1.0	-0.1
Fluid intelligence score	0.6	1.2	5.1	-0.7	0.7	1.3	0.5	0.4	0.4	-0.2	1.4	-0.3	1.3	1.3	1.1	1.3	1.7	-0.3	2.2
Illnesses of siblings	1.3	1.9	4.2	-0.2	-1.5	-1.8	-2.0	1.8	-0.4	-0.1	-1.8	0.7	-1.2	-1.8	-0.8	-1.9	-1.7	0.0	-0.9
Neuroticism score	0.4	0.8	2.0	-0.2	-1.0	-0.9	-0.4	0.9	-1.4	-0.9	-1.2	-0.4	-0.7	-0.8	-1.0	-1.1	-1.1	-0.9	-0.8
Weight	1.1	5.3	16.8	1.2	-4.1	-1.8	-2.3	2.3	-3.3	3.2	-2.0	3.3	-3.6	0.8	0.2	-1.3	-0.4	-0.7	-1.2
Impedance of arm (right)	1.8	8.5	20.5	0.4	4.5	3.5	3.7	-1.2	3.5	-1.4	3.7	-1.8	4.2	1.6	2.0	3.0	2.7	1.6	3.6
Arm fat percentage (right)	0.4	1.7	5.7	2.0	-1.7	-0.4	-0.4	2.4	-1.9	1.9	-0.6	1.8	-1.6	0.9	0.7	0.3	0.2	-0.1	-0.5
Trunk fat-free mass	1.5	8.6	24.8	0.2	-5.0	-3.0	-3.5	1.6	-3.5	3.2	-3.3	3.9	-4.4	-0.5	-1.0	-3.0	-1.8	-0.7	-2.6
Hip circumference	1.2	5.1	16.0	1.3	-4.0	-2.0	-2.2	1.9	-3.7	2.5	-2.2	2.5	-3.5	0.3	-0.4	-1.3	-0.9	-1.0	-2.1
Time employed in main current job	1.2	1.3	5.9	-1.5	-0.8	-0.7	-1.1	2.0	-1.2	-0.9	-0.7	-0.9	-0.1	-0.7	-0.1	-0.7	-0.9	-2.4	-1.1
Alcohol intake versus 10 years previously	1.9	2.8	7.1	-0.8	-2.1	-1.9	-2.1	2.7	-1.0	-0.1	-1.8	-0.0	-2.2	-0.6	-1.3	-2.5	-1.5	-1.6	-1.4
Father’s age at death	0.6	0.8	3.3	-1.8	1.5	0.2	0.7	-1.8	1.0	-0.5	0.3	-0.3	0.4	-0.3	-0.3	0.2	-0.2	1.3	-0.1
Worrier / anxious feelings	0.9	1.7	3.9	-0.1	-0.4	-1.2	-0.7	0.2	-0.5	-2.0	-1.4	-1.5	-0.3	-1.8	-1.7	-1.6	-2.0	-1.1	-1.6
Frequency of tiredness / lethargy in last 2 weeks	3.9	6.4	23.7	-1.7	-4.1	-2.4	-2.6	1.9	-4.9	0.5	-2.8	0.3	-3.4	-0.4	-1.2	-2.3	-1.9	-3.1	-1.9
Falls in the last year	0.8	1.1	4.1	0.6	-2.0	-1.0	-1.0	1.5	-1.6	0.6	-1.1	0.6	-1.5	-0.0	-0.7	-0.5	-0.7	-0.5	-0.5
Hair/balding pattern: Pattern 3	1.3	1.9	8.2	1.0	1.3	1.3	1.5	2.9	1.0	1.1	1.3	0.7	1.2	1.0	1.7	1.6	1.4	0.6	0.9
Number of live births	0.2	0.3	1.9	1.4	0.5	-0.2	-0.2	1.2	0.1	-0.2	-0.2	-0.1	0.1	-0.5	-0.4	-0.3	-0.3	-0.1	-0.8
Forced expiratory volume in 1-second (FEV1)	0.6	2.2	7.7	-1.0	-0.1	-1.4	-1.7	-1.3	1.4	-1.4	-1.6	-0.6	-0.3	-2.3	-1.3	-2.8	-2.0	-0.5	-0.9
Pulse rate	0.7	1.2	4.7	1.1	1.8	1.0	1.1	-1.0	2.2	-0.8	1.0	-1.4	0.5	0.4	-0.5	0.9	0.7	-0.1	0.6
Happiness	1.3	1.5	6.6	-1.6	-2.0	-0.7	-1.3	1.3	-2.6	-0.4	-1.0	-0.2	-0.4	-0.4	-0.2	-1.2	-0.6	-2.1	-0.4
Noisy workplace	1.8	2.2	6.6	0.5	-2.1	-1.5	-1.1	0.1	-2.6	0.8	-1.7	0.6	-2.3	-0.1	-1.2	-1.2	-1.2	-1.8	-1.9
Qualifications: A levels/AS levels or equivalent	0.9	2.1	5.7	2.1	2.1	1.4	0.6	-1.5	2.4	0.5	1.6	0.6	1.9	0.4	1.2	1.7	1.2	0.6	0.8
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	7.1	0.3	-1.7	-0.4	-0.2	1.5	-2.7	1.1	-0.3	0.9	-0.4	0.6	0.8	0.3	0.2	-2.6	-0.6
Mouth/teeth dental problems: Dentures	0.5	0.9	4.2	0.4	0.6	0.3	0.8	2.1	-0.9	0.2	0.4	0.2	1.3	-0.5	1.2	0.9	0.2	-1.6	-0.7
Asthma	0.2	0.5	3.7	0.4	0.3	-0.1	-0.3	1.2	-0.4	-0.8	-0.1	-1.0	0.3	-0.2	-0.2	-0.5	-0.0	-1.9	-0.0
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.2	6.0	-1.3	-1.5	-1.6	-2.4	1.1	-0.3	-0.1	-1.9	-0.3	-2.4	-0.9	-1.3	-2.4	-1.6	-0.6	-1.1
Medication: Cholesterol lowering	0.2	0.3	1.3	0.2	-0.9	-0.2	-0.2	1.1	-0.5	0.4	-0.4	-0.1	-1.0	0.2	-0.2	0.4	0.0	0.3	0.3
Depression (self-reported)	1.3	1.6	5.0	-1.1	-1.0	-1.5	-0.9	-1.0	-1.1	-0.4	-1.6	-0.1	-1.6	-1.5	-1.1	-1.1	-1.6	0.4	-2.2
Medication: Lansoprazole	0.8	0.9	2.6	0.9	-0.2	-0.9	-1.1	0.9	-0.0	-1.2	-0.9	-1.6	-1.4	-0.5	-1.3	-1.2	-0.8	-0.6	-0.5
Prospective memory result	0.4	0.5	1.6	-1.3	-0.7	-0.7	-0.4	0.2	-0.9	0.6	-0.7	0.8	-0.1	-0.8	0.4	-0.6	-0.6	-0.2	-1.1
Lung cancer (father)	0.3	0.3	0.9	0.5	0.6	0.5	1.0	0.1	0.5	-0.4	0.6	-0.7	0.4	0.5	0.2	0.8	0.4	0.3	0.5
Illnesses of mother	1.3	1.6	4.1	0.5	-0.9	-1.4	-0.5	-0.4	-0.0	-0.2	-1.6	0.3	-1.3	-1.7	-1.5	-2.0	-1.8	0.5	-2.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	5.6	-0.8	0.7	-0.1	-0.5	-2.4	1.6	-0.2	-0.2	0.4	0.6	-0.9	0.0	-1.3	-0.6	-0.1	0.0
Pulse wave Arterial Stiffness index	3.1	3.6	9.1	-0.8	-3.0	-2.4	-2.3	0.4	-2.0	0.3	-2.4	0.7	-2.5	-1.2	-1.8	-2.2	-1.9	-1.4	-2.3
Impedance of arm (left)	1.7	7.8	15.0	0.3	3.9	3.5	3.4	-0.9	2.6	-1.4	3.6	-1.9	3.8	2.0	2.1	3.6	2.9	1.3	3.7
Arm fat mass (right)	0.8	3.1	8.0	1.6	-2.8	-1.1	-1.3	2.7	-2.5	2.5	-1.3	2.6	-2.4	0.7	0.5	-0.5	-0.1	-0.6	-0.9
Trunk predicted mass	1.5	8.5	24.1	0.2	-4.9	-3.0	-3.5	1.6	-3.4	3.2	-3.3	3.9	-4.4	-0.5	-1.0	-3.0	-1.8	-0.6	-2.5
Standing height	0.2	2.1	8.1	-0.7	-2.3	-0.1	-0.8	0.5	-1.7	2.8	-0.2	2.9	-1.4	1.7	1.4	-0.2	1.0	0.2	0.9
Length of working week for main job	1.3	1.4	5.2	-2.3	1.2	1.0	0.8	0.1	0.9	0.4	1.2	0.2	1.2	1.0	1.5	0.3	1.5	-0.8	2.2
Exposure to tobacco smoke at home	0.3	0.4	1.3	0.1	0.1	0.8	0.8	-0.4	-0.2	-0.6	0.7	-0.9	0.5	0.7	0.2	0.1	0.7	-0.1	1.1
Breastfed as a baby	0.3	0.3	1.7	-1.3	-0.3	0.0	0.1	0.7	-0.6	-0.4	-0.0	-0.8	-0.3	0.3	-0.3	-0.2	-0.2	-1.1	-0.5
Tense / ‘highly strung’	1.0	1.6	3.7	-0.8	-0.6	-1.6	-0.8	0.7	-0.0	-1.1	-1.7	-0.8	-1.1	-1.9	-1.5	-1.3	-1.9	0.2	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.5	5.3	-0.7	-0.9	-1.7	-1.3	0.3	-1.2	-2.1	-1.9	-2.0	-1.2	-2.0	-1.9	-1.2	-2.0	-1.1	-2.3
Hair/balding pattern: Pattern 4	0.4	1.1	3.0	-1.6	-1.3	0.6	-0.2	-1.0	-1.0	1.6	0.3	1.7	-0.6	1.3	0.8	0.6	0.8	0.7	0.8
Birth weight of first child	1.3	2.3	12.3	3.5	-1.1	0.8	0.2	0.6	-1.1	2.1	0.6	1.9	-0.8	2.3	1.1	0.7	1.4	0.8	1.5
Peak expiratory flow (PEF)	0.3	0.8	4.2	-2.0	0.3	-0.3	-0.7	-2.0	1.2	-0.6	-0.2	-0.3	-0.0	-0.5	-0.3	-0.8	-0.3	-0.2	0.6
Pulse wave reflection index	1.7	2.1	4.9	-1.3	-1.4	-1.7	-1.5	-0.9	-0.7	0.1	-1.8	0.7	-1.6	-1.6	-1.5	-2.2	-1.8	0.3	-2.1
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.1	-1.4	0.3	-0.4	-0.1	-0.5	0.3	-0.7	-0.5	-0.6	-0.6	-0.1	-0.9	-1.4	-0.6	-0.5	-0.2
Loud music exposure frequency	0.5	0.5	2.1	-1.1	0.1	0.4	0.5	-0.8	-0.7	-0.5	0.5	-0.6	0.8	0.3	0.2	0.9	0.7	-1.5	0.4
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.8	0.9	-0.4	-0.8	-1.4	-0.9	0.6	0.3	-0.7	1.0	-0.2	-0.8	-0.4	-0.9	-0.4	0.8	0.2
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	3.0	-0.0	0.5	1.7	1.7	-0.6	-1.2	-0.1	1.4	-0.3	1.5	1.3	1.1	1.7	1.3	-1.4	1.1
Blood clot in the leg (DVT)	0.5	0.7	2.6	0.1	-1.0	-0.8	-1.1	0.6	-0.2	-0.9	-1.0	-0.6	-0.1	-1.6	-0.7	-0.5	-1.0	-0.6	-0.6
Medication: Paracetamol	2.2	3.7	8.0	0.3	-2.6	-2.3	-1.3	2.8	-2.6	-0.1	-2.4	-0.5	-2.3	-0.9	-1.1	-2.0	-1.7	-2.6	-1.9
Headache pain in last month	1.7	3.0	13.8	-1.5	-3.1	-1.2	-1.1	0.7	-3.7	-0.1	-1.4	-1.0	-3.0	0.9	-1.1	-0.7	-0.9	-1.8	-0.6
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	4.8	-0.3	-0.5	-1.0	-0.5	-1.2	-0.3	-1.7	-0.9	-1.0	0.3	-1.4	-1.0	-1.8	-1.3	-2.2	-1.4
Glaucoma (self-reported)	0.9	1.0	2.9	-1.4	-0.3	-0.4	-0.3	-1.3	0.6	-1.0	-0.4	-1.4	-1.7	0.5	-1.7	-0.4	-0.2	1.6	0.4
Gout (self-reported)	0.7	0.9	2.8	1.1	-1.4	-1.0	-1.0	1.7	-0.6	-0.3	-1.2	-0.4	-1.2	-0.4	-0.7	-1.2	-0.9	-0.4	-0.4
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	2.5	1.2	-0.9	-1.0	-1.6	-0.1	-0.1	-0.4	-1.3	0.2	-0.6	-1.5	-1.0	-1.5	-1.6	0.3	-1.2
Medication: Amlodipine	0.5	0.7	3.9	1.2	0.9	0.7	0.3	0.3	1.1	0.1	0.7	-0.2	0.2	0.5	0.6	1.3	0.4	2.0	0.4
Medication: Ventolin 100micrograms inhaler	0.6	0.8	3.0	0.9	0.9	-0.3	0.4	1.3	0.3	-1.6	-0.3	-1.7	0.1	-0.5	-1.0	-0.4	-0.6	-1.2	-0.5
Birth weight	0.5	1.2	3.2	0.2	-0.7	0.7	0.8	1.7	-0.7	1.7	0.6	1.5	0.2	1.3	1.8	0.5	1.3	-0.2	1.0
Chronic bronchitis/emphysema (mother)	2.4	2.8	5.1	-1.1	-1.6	-2.2	-1.9	-0.0	-0.7	-1.9	-2.2	-1.2	-1.3	-2.0	-2.3	-1.8	-2.1	-1.4	-1.6
High blood pressure (siblings)	0.4	0.5	2.2	-0.8	0.4	1.1	0.7	-0.5	-0.1	-0.0	0.9	-0.3	0.8	0.9	0.6	1.5	0.9	0.1	0.5
Forced vital capacity (FVC), Best measure	0.1	0.3	1.4	-0.5	0.2	-0.2	-0.4	-0.9	1.0	0.4	-0.3	0.8	-0.1	-0.2	0.1	-1.2	-0.4	-0.1	-0.1
Body fat percentage	0.5	1.9	7.1	1.8	-1.4	0.2	0.0	2.7	-1.8	2.1	0.0	1.8	-0.8	1.4	1.6	0.8	1.0	-0.7	0.3
Leg fat percentage (right)	0.5	2.0	6.7	1.8	-1.9	-0.9	-0.9	2.6	-1.5	2.0	-1.1	2.0	-1.4	0.0	0.8	-0.7	-0.3	-1.1	-0.8
Arm fat-free mass (right)	1.4	7.3	22.6	-0.5	-4.8	-2.8	-3.4	1.9	-3.6	2.8	-3.0	3.2	-4.1	-0.3	-0.7	-2.4	-1.4	-1.3	-2.2
Exposure to tobacco smoke outside home	0.7	0.9	2.4	-1.5	0.5	1.2	0.7	-1.4	0.2	-0.6	1.0	-1.1	0.2	1.3	0.3	0.7	0.9	0.0	1.3
Comparative body size at age 10	0.1	0.4	1.9	0.3	-0.8	-0.5	-0.9	0.8	-1.4	0.5	-0.5	0.5	-0.3	0.1	0.4	-0.4	-0.3	-0.9	-0.5
Number of full brothers	1.0	1.2	2.7	-0.1	1.0	1.3	0.8	-0.3	-0.5	0.7	1.4	0.7	1.5	1.1	1.6	0.8	1.6	-1.1	1.5
Worry too long after embarrassment	0.2	0.4	1.2	-0.4	-0.9	-0.6	0.3	1.1	-1.0	0.5	-0.7	0.5	-0.5	-0.4	0.1	-0.4	-0.7	-0.1	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.4	4.9	-2.1	0.3	-1.6	-0.6	-2.2	0.6	-1.9	-1.6	-1.6	-1.0	-2.2	-2.2	-1.1	-1.7	1.1	-1.0
Wheeze or whistling in the chest in last year	0.4	0.7	2.3	1.1	-1.0	-0.3	-0.7	1.5	-1.3	0.5	-0.4	0.2	-0.9	0.6	-0.1	-0.1	0.3	-1.4	-0.2
Number of children fathered	0.1	0.2	0.6	-0.5	-0.3	0.2	-0.0	0.3	-0.3	0.3	0.3	0.1	0.1	0.5	0.7	0.8	0.6	-0.1	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.3	0.3	0.0	-0.1	0.3	-0.6	0.2	0.5	0.1	0.8	0.2	0.0	0.7	-0.3	-0.2	1.1	-0.2
Age at first live birth	1.3	2.2	6.9	-0.4	-0.3	-1.6	-1.3	0.1	0.6	-2.6	-1.5	-2.3	-0.2	-2.3	-1.7	-0.8	-1.9	-1.4	-1.5
Pulse wave peak to peak time	2.7	3.2	7.3	0.8	2.7	2.3	2.1	-0.4	1.7	-0.2	2.2	-0.6	2.3	1.3	1.8	2.2	1.9	1.3	2.3
Health satisfaction	1.9	2.5	11.7	0.0	-2.6	-1.5	-0.8	0.2	-3.4	0.3	-1.8	-0.3	-2.5	0.0	-1.3	-0.9	-0.9	-1.9	-1.7
Shortness of breath walking on level ground	0.9	1.1	4.2	0.0	-0.7	-0.9	-1.1	1.9	-1.4	-0.4	-1.1	-0.4	-0.8	-0.8	-0.4	-0.5	-0.8	-2.0	-1.1
Qualifications: College or University degree	0.4	1.4	5.2	-0.1	1.4	0.2	1.1	-1.9	0.8	-2.3	0.2	-2.2	1.1	-0.7	-0.9	0.5	-0.4	-0.9	-0.3
Eye problems/disorders: None of the above	0.4	0.5	1.1	0.8	0.3	-0.4	0.7	-0.3	-0.2	-0.7	-0.4	-0.5	0.4	-1.0	-0.7	-1.0	-1.0	-1.0	-1.0
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.7	-0.1	-0.1	0.7	-0.1	1.0	-0.7	1.4	0.7	1.4	0.2	1.2	1.3	1.6	1.4	0.9	1.4
Emphysema/chronic bronchitis	0.5	0.6	2.3	0.6	-1.0	-0.2	0.0	-1.0	-1.5	1.3	-0.3	1.3	-0.6	0.5	0.0	-0.3	0.0	0.2	-0.9
Medication for pain relief, constipation, heartburn	0.6	1.1	5.3	0.6	1.3	0.4	0.4	-2.3	0.9	-1.1	0.6	-0.3	1.1	-0.7	-0.3	1.0	-0.3	2.1	-0.4
Neck or shoulder pain in last month	0.7	0.9	4.7	-1.7	0.0	0.4	-0.1	-0.2	-1.2	-1.8	0.0	-2.2	-0.4	0.4	-1.1	0.4	0.0	-1.0	0.2
Medication: Blood pressure	1.1	1.9	6.6	0.0	0.7	1.4	0.7	0.7	0.4	1.5	1.3	0.8	-0.0	1.6	1.4	2.6	1.7	2.5	1.6
Angina (self-reported)	2.5	3.3	7.5	1.9	0.6	2.2	1.8	1.2	-0.6	2.1	2.0	1.2	1.4	2.1	2.5	2.7	2.4	-0.5	1.6
Migraine (self-reported)	2.1	2.6	5.7	-1.3	-1.8	-2.0	-1.2	-0.6	-1.9	-0.6	-2.0	-0.9	-2.4	-1.0	-1.4	-2.4	-1.8	-0.7	-2.0
Medication: Ibuprofen	1.1	1.3	3.7	-0.7	-1.5	-1.1	-1.8	1.4	-0.2	0.7	-1.5	0.5	-1.8	-0.7	-0.6	-1.9	-1.0	0.1	-0.7
Medication: Allopurinol	0.3	0.4	1.9	0.6	-0.4	-0.6	-0.7	0.4	0.4	-0.4	-0.6	-0.4	-1.1	-0.2	-0.7	-0.2	-0.6	1.4	-0.5
Medication: Omeprazole	1.0	1.2	5.0	-0.5	0.9	0.8	1.4	0.2	0.1	-1.6	0.6	-2.2	0.6	0.4	-0.5	0.4	0.7	-2.2	0.7
Medication: Seretide 50 evohaler	0.2	0.2	1.0	1.0	-0.1	0.4	0.5	-0.3	-0.2	0.4	0.4	-0.0	-0.2	0.9	0.0	0.2	0.7	-0.0	0.5
Mean time to correctly identify matches	0.4	0.8	4.2	-2.1	-0.4	0.3	0.6	0.8	-0.3	1.5	0.4	1.1	0.4	0.3	1.3	0.8	0.6	-0.3	-0.0
Heart disease (mother)	1.3	1.6	4.2	0.9	0.6	1.5	0.8	-0.7	-0.4	1.4	1.4	1.0	1.2	1.8	2.0	1.3	1.7	-0.0	1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.4	-0.1	-0.3	-0.5	-0.2	1.5	0.3	-0.2	-0.6	-0.1	0.0	-1.1	-0.3	-1.3	-0.9	-0.5	-0.6
Whole body fat mass	0.7	3.0	8.6	1.6	-2.6	-0.6	-0.8	2.9	-2.5	2.8	-0.9	2.5	-2.0	1.3	1.1	-0.0	0.4	-0.7	-0.4
Leg fat mass (right)	0.9	3.6	9.4	1.3	-3.1	-1.5	-1.6	2.9	-2.5	2.6	-1.7	2.7	-2.4	0.3	0.5	-1.2	-0.4	-1.1	-1.2
Arm predicted mass (right)	1.3	6.9	21.2	-0.4	-4.6	-2.5	-3.1	2.0	-3.5	3.0	-2.8	3.4	-3.9	-0.1	-0.5	-2.3	-1.2	-1.1	-2.1
Pulse rate, automated reading	1.1	3.5	17.7	0.3	3.6	1.3	1.1	-1.9	4.2	-2.1	1.3	-1.9	2.5	-1.3	-0.6	0.6	0.2	0.5	0.6
Alcohol intake frequency.	0.6	1.5	3.8	-0.4	-1.1	0.6	0.8	1.6	-1.9	1.9	0.6	1.5	0.1	1.5	1.7	0.2	1.1	-1.5	0.4
Comparative height size at age 10	0.7	3.6	13.9	0.2	-3.7	-1.2	-1.5	1.7	-3.0	3.0	-1.3	2.9	-2.5	1.2	0.6	-1.1	0.1	-0.2	-0.2
Number of full sisters	1.1	1.4	9.0	-0.3	-1.7	-0.4	-1.0	3.0	-1.9	1.3	-0.6	1.1	-1.0	0.6	0.3	-0.3	-0.2	-0.3	-0.5
Suffer from ‘nerves’	1.0	1.6	4.3	0.1	-0.6	-1.3	-0.6	0.3	-1.2	-1.5	-1.5	-1.1	-1.0	-1.4	-1.4	-1.6	-2.1	-0.3	-1.8
Overall health rating	0.5	1.2	4.3	1.0	-1.8	-0.3	-0.9	1.3	-2.1	1.0	-0.7	0.3	-2.1	1.0	-0.5	-0.4	0.2	-0.8	-0.1
Chest pain or discomfort	0.6	0.8	7.0	0.7	-0.6	0.2	0.4	0.3	-2.6	0.4	0.1	-0.2	-0.7	1.2	0.1	0.5	0.5	-1.4	-0.5
Had major operations	2.4	2.8	7.3	-1.0	0.2	1.6	1.7	1.1	-0.9	2.7	1.7	2.2	0.7	2.5	2.4	2.1	2.0	0.3	0.8
Age at last live birth	1.6	2.4	10.5	-0.6	-0.2	-1.0	-1.2	1.6	1.0	-3.1	-1.0	-3.2	-0.5	-1.7	-1.8	-0.7	-1.5	-0.6	-0.9
Family relationship satisfaction	1.1	1.4	4.7	-0.0	0.2	-0.3	-1.0	1.2	-0.5	-2.2	-0.4	-2.1	1.0	-1.6	-0.3	-0.5	-0.7	-2.1	-0.7
Leg pain on walking	0.8	1.0	3.1	0.8	-0.8	-1.1	-1.0	0.4	-0.9	-0.4	-1.2	-0.8	-1.4	-0.7	-0.9	-0.1	-0.9	-1.2	-1.8
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.7	-1.1	-1.3	-0.2	-0.7	1.1	-1.1	0.3	-0.5	0.2	-1.0	0.5	0.1	-0.1	-0.0	0.5	0.6
Commuting to job workplace: Car/motor vehicle	0.9	1.0	4.1	0.7	-1.7	-1.0	-1.6	0.9	-2.0	-0.1	-0.9	-0.4	-1.6	0.2	-0.5	0.0	-0.7	-0.3	-0.3
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	3.2	-0.3	1.3	-0.2	0.5	-0.4	1.8	-1.6	-0.1	-1.6	0.1	-0.9	-1.5	-0.3	-0.7	1.1	-0.3
Medication: Aspirin	0.4	0.6	3.3	0.3	-0.5	0.0	-0.2	0.6	-0.0	1.8	0.1	1.3	-0.6	1.0	0.7	0.2	0.8	0.2	0.7
Supplements: Vitamin C	2.4	2.8	6.2	-1.2	-0.4	-2.2	-1.6	0.0	-0.4	-2.0	-2.1	-1.6	-1.0	-2.4	-2.0	-1.5	-2.5	-0.9	-2.1
Knee pain experienced in last month	0.3	0.5	4.1	2.0	0.3	0.2	-0.1	0.4	-0.3	0.1	0.1	-0.6	-1.0	1.0	-0.6	-0.2	0.4	-0.6	-0.3
Hypertension (Self-reported)	0.2	0.5	1.4	1.0	0.2	0.6	-0.1	0.2	0.3	0.8	0.5	0.3	-0.4	0.8	0.7	1.1	0.8	1.2	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.1	-1.0	-0.1	-0.8	-0.5	-1.0	1.0	-0.8	-0.9	-0.7	-0.8	-1.3	-1.0	-1.4	-1.1	0.4	-0.7
Illnesses of father: Heart disease	1.4	2.0	7.2	-0.8	0.0	1.6	0.7	0.5	0.2	1.4	1.6	1.2	0.8	2.2	1.7	1.2	2.1	0.4	2.7
Illnesses of siblings: Diabetes	0.7	0.8	2.6	-0.9	-0.1	0.6	0.9	-1.4	-1.6	0.9	0.6	0.4	0.1	1.5	0.7	0.5	0.9	-1.0	-0.4
Smoking status: Previous	0.0	0.1	0.3	0.2	-0.1	-0.3	-0.5	0.0	-0.3	-0.1	-0.2	-0.2	-0.2	0.1	0.2	0.5	0.0	0.3	0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	2.7	-0.9	-0.7	0.2	-0.4	-0.8	-0.1	1.6	0.2	1.5	-1.1	1.4	0.7	-0.0	0.8	1.0	0.9
Whole body fat-free mass	1.4	7.8	24.0	0.3	-4.9	-2.7	-3.3	1.8	-3.6	3.2	-3.0	3.7	-4.4	-0.0	-0.8	-2.5	-1.4	-0.6	-2.2
Leg fat-free mass (right)	1.1	5.6	19.1	0.3	-4.4	-2.0	-2.6	2.0	-3.5	2.8	-2.2	2.8	-4.0	0.8	-0.5	-1.6	-0.7	-0.3	-1.4
Arm fat percentage (left)	0.5	2.0	7.1	2.3	-1.9	-0.5	-0.5	2.7	-2.2	1.8	-0.7	1.6	-1.7	1.0	0.6	0.4	0.3	-0.4	-0.5
Average weekly red wine intake	1.6	2.3	9.6	-1.3	-0.4	-1.7	-0.9	1.1	-0.2	-1.7	-1.6	-0.9	0.1	-3.1	-1.0	-0.9	-2.0	-2.0	-2.1
Handedness (chirality/laterality): Left-handed	0.7	0.9	2.8	1.7	0.3	-0.9	-0.8	-1.5	0.4	-0.3	-0.8	0.3	-0.6	-0.7	-0.7	-1.3	-1.2	1.1	-0.8
Mood swings	0.7	1.3	5.7	-1.1	-2.0	-0.9	-1.0	1.1	-2.4	-0.2	-1.1	0.3	-1.0	-0.2	-0.5	-0.8	-0.8	-1.9	-0.5
Loneliness, isolation	0.9	1.2	4.9	0.5	-2.2	-1.0	-0.8	1.2	-2.2	-0.3	-1.2	-0.0	-0.7	-0.5	-0.3	-0.7	-0.7	-1.3	-0.8
Long-standing illness, disability or infirmity	0.8	1.2	5.4	0.1	-1.8	-0.0	-0.8	1.7	-2.3	1.0	-0.3	0.3	-1.2	1.2	0.5	0.3	0.7	-1.6	0.6
Ever had bowel cancer screening	0.3	0.4	1.6	0.4	1.2	0.3	0.2	1.2	0.9	0.2	0.2	0.4	0.9	-0.3	0.4	-0.6	-0.0	-0.0	0.3
Diabetes diagnosed by doctor	0.5	0.8	2.2	1.5	0.2	0.9	0.9	0.7	0.0	1.3	0.8	0.8	-0.3	1.3	1.1	0.4	0.9	1.1	0.5
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	3.0	-1.7	-1.7	-1.4	-1.4	0.5	-1.1	-0.6	-1.6	-0.2	-1.6	-0.9	-1.4	-1.6	-1.3	-0.3	-1.1
Friendships satisfaction	0.3	0.3	1.9	-0.1	-0.4	0.3	-0.1	1.1	-1.4	-0.7	0.1	-0.8	0.4	0.0	0.1	-0.5	0.0	-0.6	0.2
Qualifications: nursing, teaching	1.3	2.0	7.8	1.7	0.8	-0.8	-0.6	-0.7	1.2	-2.8	-0.6	-2.6	0.6	-2.1	-1.4	0.1	-1.2	-0.6	-1.4
Commuting to job workplace: Walk	0.7	0.7	2.1	-0.0	-0.7	-0.9	-0.4	-1.1	-0.8	-0.8	-0.9	-0.8	-1.4	-0.7	-1.1	-0.6	-1.0	0.2	-1.1
Eye problems/disorders: Cataract	0.6	0.7	3.4	-1.3	-0.0	0.1	-0.5	1.8	-0.2	0.8	0.2	1.0	0.6	0.1	1.3	1.0	0.5	-0.3	0.8
Mouth/teeth dental problems: Mouth ulcers	0.5	0.9	4.4	0.3	1.0	0.0	-0.0	0.6	1.0	-2.0	-0.2	-2.1	0.4	-0.9	-0.6	-0.8	-0.6	-0.7	-0.0
Medication for cholesterol	0.4	0.7	1.8	-1.0	-1.4	-1.0	-1.0	0.8	-1.2	0.7	-0.9	1.0	-0.7	-0.2	-0.3	-0.6	-0.3	-0.6	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	2.7	-0.6	-0.4	0.0	0.2	0.4	-0.8	0.2	-0.1	-0.1	0.2	0.0	0.1	0.2	0.4	-1.6	0.1
Back pain experienced in last month	0.8	1.1	5.1	-0.2	-1.1	-0.7	-0.7	0.1	-1.8	0.2	-1.0	-0.2	-1.2	-0.2	-0.8	-0.8	-0.9	-2.2	-1.8
Mineral and other dietary supplements	0.5	0.7	2.1	1.5	0.6	0.9	0.6	-0.3	1.4	-0.8	0.6	-0.5	1.3	-0.5	-0.1	0.7	0.6	-0.1	1.1
Breast cancer (self-reported)	0.3	0.3	2.3	-0.3	-0.2	0.1	-0.5	0.2	-0.8	-0.5	0.1	-0.7	0.2	-0.1	-0.2	0.7	0.4	-1.5	0.2
Asthma (self-reported)	0.3	0.6	3.8	0.8	0.6	0.2	-0.1	1.2	0.1	-0.8	0.2	-1.0	0.8	-0.2	-0.0	-0.5	0.2	-1.9	0.3
Osteoporosis (self-reported)	2.0	2.4	9.2	-2.2	-0.3	-1.6	-1.0	0.8	0.7	-1.8	-1.6	-1.4	-0.2	-2.2	-1.3	-3.0	-2.0	-0.9	-1.2
Osteoarthritis (self-reported)	2.6	3.3	7.3	1.1	-2.1	-2.4	-2.7	0.5	-0.8	-0.6	-2.4	-0.3	-2.3	-2.0	-1.8	-2.4	-2.1	-0.3	-2.1
Medication: Aspirin	0.3	0.4	2.3	0.4	-0.8	-0.4	-0.7	0.6	0.0	1.5	-0.3	1.2	-0.6	0.2	0.4	-0.0	0.3	-0.1	0.4
Medication: Gliclazide	0.7	0.8	3.3	-1.7	-1.1	0.1	-0.6	1.8	-0.9	0.9	0.1	0.2	-1.3	1.4	0.3	0.2	0.2	-0.3	0.3
Illnesses of father: None of the above (group 1)	0.3	0.4	1.1	-0.4	0.8	-0.0	0.4	-0.8	0.3	-0.2	0.0	-0.1	0.8	-0.9	-0.1	-0.7	-0.5	-0.6	-1.1
Smoking status: Current	0.6	0.9	4.6	-0.5	-1.8	-1.1	-0.6	-0.1	-2.1	1.3	-0.8	1.2	-1.1	0.2	-0.2	-0.4	-0.1	-0.1	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	4.7	1.6	1.4	-0.3	0.3	-1.9	2.2	-1.2	-0.4	-0.9	0.1	-1.4	-1.3	-1.1	-1.1	1.1	-0.9
Whole body water mass	1.3	7.5	23.0	0.3	-4.8	-2.7	-3.3	1.8	-3.5	3.2	-3.0	3.6	-4.3	-0.0	-0.7	-2.5	-1.4	-0.6	-2.1
Leg predicted mass (right)	1.0	5.5	18.7	0.3	-4.3	-2.0	-2.6	2.1	-3.5	2.8	-2.2	2.8	-4.0	0.8	-0.4	-1.6	-0.6	-0.4	-1.3
Arm fat mass (left)	0.8	3.3	8.3	1.9	-2.9	-1.2	-1.3	2.9	-2.7	2.4	-1.4	2.3	-2.6	0.7	0.3	-0.6	-0.2	-0.7	-1.1
Number of self-reported non-cancer illnesses	2.0	3.4	8.8	0.0	-3.0	-2.2	-2.3	2.5	-2.5	0.5	-2.3	0.3	-2.8	-0.8	-0.7	-1.9	-1.5	-0.9	-1.4
Average weekly champagne plus white wine intake	0.4	0.6	2.2	-1.0	1.5	0.4	0.3	-1.1	1.4	0.0	0.3	0.6	1.3	-0.6	0.0	-0.0	0.2	0.4	0.1
Miserableness	2.5	4.4	8.7	-1.5	-2.9	-2.5	-2.9	1.6	-2.5	-0.9	-2.7	-0.3	-2.5	-1.5	-1.7	-2.4	-2.1	-1.7	-1.6
Guilty feelings	0.9	1.3	3.5	0.3	-1.4	-1.4	-0.9	0.5	-1.4	-0.4	-1.5	-0.3	-1.2	-1.2	-1.1	-1.0	-1.5	-0.2	-1.9
Wears glasses or contact lenses	0.2	0.3	1.9	0.6	-0.8	-0.3	-0.6	0.1	-1.4	0.2	-0.1	-0.0	-0.4	0.5	0.4	0.2	0.0	-0.1	-0.1
Ever taken oral contraceptive pill	0.9	1.1	6.9	2.6	-0.6	-0.9	0.1	1.0	-1.7	-0.6	-0.8	-0.8	-0.9	-0.1	-0.6	-0.3	-0.8	-0.6	-1.0
Hearing aid user	0.9	1.0	3.3	0.7	1.6	0.7	0.7	1.2	1.5	-0.8	0.7	-0.8	1.8	-0.9	0.8	0.3	0.6	-0.9	0.6
Mother’s age at death	0.6	0.8	2.1	0.4	1.1	-0.0	0.1	0.7	1.4	-1.4	-0.1	-1.3	0.2	-1.2	-1.1	-0.1	-0.9	0.8	-0.6
Financial situation satisfaction	0.7	0.9	2.5	0.2	-0.9	-0.9	-0.1	0.8	-1.0	-0.1	-1.1	-0.2	-0.8	-0.5	-1.0	-1.3	-0.9	-1.6	-1.6
Tinnitus: Yes, now most or all of the time	4.1	4.8	8.3	-0.0	-1.6	-2.8	-2.4	2.1	-1.3	-2.4	-2.7	-2.0	-1.2	-2.9	-2.3	-2.2	-2.6	-2.7	-2.0
Commuting to job workplace: Public transport	0.4	0.5	1.9	-0.8	0.1	0.4	0.1	1.4	0.9	-0.1	0.3	-0.0	1.3	-0.5	0.7	0.1	0.4	-0.9	0.2
Eye problems/disorders: Glaucoma	0.4	0.5	2.7	-0.9	-0.0	0.2	0.4	-1.2	0.3	0.3	0.1	-0.1	-1.0	1.0	-0.5	-0.0	0.4	1.7	0.3
Medication: Blood pressure	0.4	0.8	2.3	1.5	0.9	1.2	0.9	-0.6	0.5	0.3	1.2	-0.0	0.5	1.1	0.6	1.1	0.9	0.6	0.7
Pain type(s) experienced in last month: Hip pain	1.5	1.9	3.5	-0.9	-1.2	-1.5	-1.5	-0.1	-0.7	-1.3	-1.6	-1.4	-1.5	-1.2	-1.8	-1.3	-1.5	-1.9	-1.4
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.2	-1.3	-1.0	-1.5	-1.4	-0.3	-1.0	0.4	-1.1	0.7	-1.0	-0.6	-0.2	-0.9	-1.1	0.2	-1.4
High cholesterol (Self-reported)	0.2	0.4	1.0	-0.4	-0.6	-0.6	0.1	-0.3	-0.5	-0.6	-0.9	-1.0	-0.8	-0.7	-0.8	-0.6	-0.9	-0.2	-0.6
Medication: Bendroflumethiazide	0.3	0.5	4.1	2.0	-0.3	-0.3	0.4	0.8	-0.3	-0.4	-0.4	-0.7	-0.6	-0.3	-0.6	0.6	-0.5	0.5	-0.7
Medication: Paracetamol	3.7	5.8	13.7	-0.2	-3.7	-2.8	-2.0	2.9	-3.7	-0.1	-2.9	-0.5	-3.0	-1.1	-1.2	-2.5	-2.0	-3.2	-2.1
Medication: Lisinopril	0.7	1.0	3.0	-1.3	-1.4	-0.8	-1.5	0.7	-0.5	1.3	-0.8	1.3	-1.7	0.3	-0.1	-0.2	-0.4	0.6	-0.4
Medication: Atorvastatin	0.7	0.9	2.3	0.8	0.8	1.0	0.9	0.6	0.6	1.0	0.8	1.1	1.5	0.2	1.5	0.8	1.1	-0.4	0.9
Illnesses of father: High blood pressure	0.6	0.7	2.0	-1.3	-1.0	-0.7	0.4	0.7	-1.4	-0.6	-0.8	-0.8	-0.6	-0.4	-0.4	0.4	-0.4	-1.4	-0.8
Alcohol drinker status: Never	0.6	0.8	1.9	0.9	0.5	0.8	1.3	1.2	-0.4	0.8	0.7	0.4	1.3	0.3	1.4	1.0	0.7	-0.9	-0.1
Ever smoked	0.1	0.2	0.8	-0.3	-0.2	-0.4	-0.9	-0.2	-0.9	0.1	-0.2	0.2	-0.2	-0.1	0.3	0.5	-0.0	0.5	-0.0
Basal metabolic rate	1.3	7.3	22.7	0.5	-4.8	-2.5	-3.0	2.1	-3.6	3.3	-2.8	3.6	-4.2	0.2	-0.5	-2.3	-1.1	-0.7	-2.0
Leg fat percentage (left)	0.4	1.5	5.5	1.5	-1.7	-0.6	-0.5	2.4	-1.6	1.9	-0.7	1.8	-1.2	0.5	1.0	-0.2	0.1	-1.0	-0.4
Arm fat-free mass (left)	1.3	6.4	18.7	-0.0	-4.3	-2.6	-2.9	1.7	-3.3	2.8	-2.8	3.1	-3.8	-0.2	-0.6	-2.6	-1.3	-1.3	-2.2
Number of operations (self-reported)	1.0	1.5	5.0	-1.7	-0.0	1.0	0.5	-0.2	-0.4	2.2	0.9	2.2	0.6	1.5	1.8	1.0	1.2	-0.3	0.7
Average weekly beer plus cider intake	1.2	1.8	5.1	-1.2	-0.4	-0.7	-0.8	-2.3	-0.8	-1.5	-0.6	-1.9	-2.3	0.7	-1.7	-0.3	-0.8	2.1	-0.2
Irritability	0.5	0.9	1.8	1.3	1.0	1.2	1.3	0.5	-0.5	-0.5	1.0	-0.6	1.3	0.7	0.9	1.3	0.7	-0.1	1.2
Risk taking	0.5	0.8	2.8	-1.4	-1.5	-0.7	-0.3	0.8	-1.7	-0.1	-0.8	-0.0	-0.7	-0.2	-0.2	-0.5	-0.0	-1.6	0.2
Ever had prostate specific antigen (PSA) test	1.4	1.6	5.0	-0.0	-0.7	-1.6	-0.5	1.5	0.3	-0.6	-1.6	-0.1	-0.5	-2.1	-1.3	-2.2	-1.8	-0.3	-1.7
Fractured/broken bones in last 5 years	0.5	0.6	3.5	0.4	-0.2	0.7	0.6	-1.9	0.0	0.8	0.6	0.8	-0.3	1.2	0.0	0.3	0.6	1.3	0.4
Age started oral contraceptive pill	1.5	1.9	4.9	1.9	1.7	1.5	2.0	-2.2	0.5	-1.1	1.5	-1.5	2.1	0.4	0.3	1.2	0.9	-0.6	0.3
Diastolic blood pressure, automated reading	1.4	4.4	10.2	-0.0	-0.4	-2.0	-1.7	-1.0	-0.1	-3.2	-2.2	-3.1	-1.4	-2.5	-2.9	-2.4	-2.7	-1.7	-2.4
Ever depressed for a whole week	1.3	1.6	2.6	-0.4	-1.3	-1.4	-1.5	0.1	-0.7	-1.3	-1.6	-1.5	-1.5	-1.2	-1.6	-1.4	-1.5	-1.2	-1.2
Unable to work because of sickness or disability	0.9	1.2	3.3	-1.1	0.4	1.3	0.5	0.6	-0.4	1.2	1.1	0.9	1.0	1.0	1.8	1.4	1.5	-0.0	1.3
Commuting to job workplace: Cycle	0.4	0.5	1.7	0.6	1.3	0.5	1.0	-0.8	1.0	-0.4	0.5	-0.2	1.3	-0.3	0.3	0.3	0.5	-0.4	0.5
Myopia	0.6	0.9	2.4	-1.5	0.2	-1.0	-0.7	0.3	0.5	-1.0	-0.6	-1.4	-1.4	-0.1	-1.2	-0.5	-0.7	1.4	0.4
Vascular/heart problems diagnosed by doctor	0.1	0.4	2.4	-1.5	-0.4	-0.4	-0.2	-0.7	-0.5	-0.3	-0.3	0.2	0.2	-0.3	-0.6	-1.2	-0.5	-0.6	-0.3
Cholesterol lowering medication	0.6	0.8	1.8	-0.1	0.8	1.4	1.3	0.3	0.0	-0.3	1.2	-0.8	1.2	0.9	1.1	1.0	0.9	-0.9	0.9
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	3.8	-0.3	1.2	1.4	1.8	0.4	0.5	-1.2	1.2	-1.9	1.0	1.0	0.1	0.8	1.1	-1.7	1.3
Pain experienced in last month	0.6	1.0	4.7	0.4	0.9	-0.3	-0.4	0.0	2.2	0.5	0.1	1.6	1.4	-1.3	0.8	-0.3	-0.1	1.5	0.1
Supplements: Calcium	2.8	3.1	10.1	-1.9	-0.1	-1.5	-0.8	1.3	-0.5	-2.7	-1.3	-2.8	0.0	-2.0	-1.4	-1.5	-2.0	-3.2	-1.4
Basal cell carcinoma (self-reported)	1.4	1.6	5.6	-2.4	-1.9	-1.5	-1.9	0.4	-0.4	0.2	-1.7	0.5	-1.5	-1.1	-0.7	-1.2	-1.3	-0.1	-0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.7	-0.8	-1.1	-0.2	-0.6	1.3	-1.0	1.0	-0.2	1.0	-0.0	-0.2	0.6	0.2	0.1	-1.0	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.6	-0.1	-1.2	-1.1	-1.1	0.5	-0.2	-0.6	-1.2	-0.3	-0.6	-1.6	-0.9	-0.8	-1.2	-0.3	-0.8
Heart disease (siblings)	1.4	1.7	4.4	0.2	1.2	1.4	1.8	-2.1	0.2	-0.5	1.6	-1.3	0.8	1.9	0.6	1.4	1.6	0.3	1.7
Alcohol drinker status: Previous	1.7	2.0	5.5	1.2	0.4	1.7	1.6	0.7	-0.5	1.2	1.7	0.8	1.0	2.2	2.3	1.5	1.6	-0.3	1.6
Pack years of smoking	0.8	1.2	3.6	1.5	-0.8	0.5	0.6	0.2	-1.6	1.9	0.4	1.4	-0.6	1.7	0.9	0.7	1.4	0.3	0.8
Impedance of whole body	2.0	10.4	23.2	-0.5	4.7	4.0	4.1	-1.4	3.2	-1.2	4.2	-1.8	4.8	2.0	2.8	3.6	3.4	0.9	4.1
Leg fat mass (left)	0.8	3.1	8.0	1.2	-2.8	-1.2	-1.4	2.6	-2.4	2.5	-1.5	2.5	-2.3	0.5	0.6	-0.9	-0.2	-1.0	-1.0
Arm predicted mass (left)	1.2	5.9	17.5	-0.2	-4.2	-2.3	-2.7	1.7	-3.1	3.1	-2.6	3.4	-3.7	0.1	-0.3	-2.3	-1.1	-0.8	-1.8