Best TWAS P=1.28e-07 · Best GWAS P=1.8e-07 conditioned to 0.358
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ADCY3 | 0.16 | 0.12 | lasso | 10 | 0.14 | 3.2e-17 | 5.2 | -5.2 | 2.5e-07 | -0.89 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Nerve Tibial | ADCY3 | 0.09 | 0.05 | enet | 6 | 0.03 | 2.2e-03 | 4.3 | -5.3 | 1.3e-07 | -0.92 | 0.01 | 0.98 | TRUE |