Hub : Genes

ADCY3

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1560	0.0370	3.4e-15	0.119	0.142	0.134	0.140	0.145	2.4e-14	6.0e-17	5.2e-16	9.9e-17	3.2e-17
2	GTEx	Adipose Subcutaneous	0.0650	0.0260	6.3e-04	0.039	NA	0.007	NA	0.012	3.8e-04	NA	7.7e-02	NA	3.1e-02
3	GTEx	Artery Tibial	0.2104	0.0514	2.2e-09	0.136	NA	0.138	NA	0.154	8.8e-11	NA	5.7e-11	NA	4.3e-12
4	GTEx	Cells EBV-transformed lymphocytes	0.2500	0.0800	2.0e-05	0.228	NA	0.121	NA	0.008	5.5e-08	NA	9.2e-05	NA	1.7e-01
5	GTEx	Esophagus Mucosa	0.0560	0.0250	4.6e-03	0.054	NA	0.014	NA	0.026	1.8e-04	NA	3.6e-02	NA	6.8e-03
6	GTEx	Nerve Tibial	0.0873	0.0384	3.6e-04	0.047	NA	0.032	NA	0.018	3.1e-04	NA	2.3e-03	NA	1.7e-02
7	GTEx	Whole Blood	0.2340	0.0460	0.0e+00	0.237	NA	0.271	NA	0.200	1.1e-21	NA	5.5e-25	NA	3.5e-18
8	ROSMAP	Brain Pre-frontal Cortex	0.1660	0.0326	0.0e+00	0.260	0.222	0.257	0.251	0.252	2.7e-33	5.4e-28	6.8e-33	5.6e-32	3.3e-32
9	YFS	Blood	0.0714	0.0245	1.1e-07	0.022	0.024	0.035	0.043	0.017	6.7e-08	2.5e-08	1.4e-11	7.3e-14	1.8e-06
10	TCGA	Breast Invasive Carcinoma	0.0531	0.0229	2.2e-06	0.030	0.031	0.030	NA	0.021	6.4e-07	5.0e-07	7.6e-07	NA	2.8e-05
11	TCGA	Glioblastoma Multiforme	0.3610	0.1490	3.3e-03	0.145	0.111	0.131	NA	0.114	3.6e-05	3.0e-04	9.0e-05	NA	2.5e-04
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.0840	0.0470	9.4e-03	0.027	0.013	0.032	NA	0.022	4.5e-04	1.1e-02	1.5e-04	NA	1.3e-03
13	TCGA	Brain Lower Grade Glioma	0.0282	0.0149	5.5e-04	0.017	0.025	0.010	NA	0.014	3.9e-03	7.1e-04	2.1e-02	NA	8.3e-03
14	TCGA	Lung Squamous Cell Carcinoma	0.0575	0.0324	3.7e-03	0.007	0.018	0.023	NA	0.014	5.2e-02	3.2e-03	1.0e-03	NA	7.8e-03
15	TCGA	Prostate Adenocarcinoma	0.0852	0.0402	2.6e-03	0.020	0.019	0.042	NA	0.034	3.4e-03	4.0e-03	3.2e-05	NA	1.8e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	0.8	1.3	4.7	-1.5	0.1	1.4	0.7	-1.9	-0.6	1.3	-0.7	0.1	-0.4	2.2	0.7	0.5	-0.4	1.7
Bipolar Disorder or Schizophrenia	0.1	0.3	1.3	-0.5	0.5	0.6	0.2	0.0	-0.0	0.6	-0.0	0.2	0.4	1.1	-0.4	-0.0	0.1	1.1
Depressed Affect (Nagel 2018)	1.4	3.0	7.1	-1.6	2.6	1.8	-2.2	2.4	-2.1	1.8	-2.2	0.6	0.1	-1.0	-0.3	-2.7	0.3	0.4
Depression (Nagel 2018)	1.6	2.5	6.6	-1.8	1.8	0.7	-1.2	2.6	-1.5	1.6	-1.9	-0.1	1.3	-0.2	0.9	-2.0	2.0	1.8
Intelligence (Savage-Jansen 2018)	2.0	6.3	17.0	-4.1	2.8	3.0	-2.5	0.9	-3.6	3.4	-3.6	-1.6	-1.6	-0.4	0.4	-3.0	-0.3	1.2
Neuroticism (Nagel 2018)	0.7	1.7	6.8	-0.7	2.0	0.5	-1.4	2.6	-0.9	1.0	-1.3	1.5	0.7	-0.6	-0.7	-2.1	0.6	0.4
Schizophrenia (2018)	0.2	0.4	2.5	0.6	0.5	-0.4	-0.3	1.6	0.4	-0.3	0.5	0.2	0.9	-0.3	-1.1	-0.4	0.5	0.1
Schizophrenia vs Biploar Disorder	0.4	0.5	1.6	1.2	0.2	-0.5	-0.7	1.1	0.0	-0.6	0.1	-0.9	0.4	-0.8	-0.9	-0.4	0.5	-0.9
Worry (Nagel 2018)	0.9	1.9	5.1	1.9	-0.6	-2.2	1.2	1.3	2.0	-1.6	1.6	2.1	0.8	0.0	-1.1	0.8	-0.1	-0.6
Alzheimer’s Disease (in mother)	0.2	0.3	0.9	-0.9	0.2	0.2	0.1	0.4	-0.4	0.8	-0.7	0.4	-0.1	-0.4	-0.6	-0.7	0.1	0.6
Alzheimer’s Disease (in father)	1.7	1.8	6.6	0.3	0.0	-0.2	-1.4	2.2	-0.4	0.1	-0.4	0.0	-1.2	-2.6	-2.4	-1.0	-1.4	-1.9
Alzheimer’s Disease (including proxy)	0.3	0.5	1.5	-0.8	0.2	-0.5	-0.4	1.1	-0.5	0.6	-0.6	-0.6	-0.3	-1.2	-0.9	-0.9	-0.0	-0.5
Crohns Disease (2017)	10.5	22.9	55.4	-7.4	4.3	5.7	-4.4	-1.2	-6.7	5.9	-5.8	-6.5	-5.3	-1.3	-0.2	-4.4	-3.2	-0.6
Irritable Bowel Disease (IBD)	9.8	23.4	52.4	-7.2	4.5	5.6	-4.7	-2.0	-6.5	6.0	-5.9	-6.7	-5.5	-1.1	-0.3	-4.4	-3.2	-1.4
Ulcerative Colitis (UC)	4.5	8.4	16.0	-4.0	3.1	3.4	-3.1	-1.5	-3.7	3.7	-3.8	-3.4	-3.3	-0.5	-0.3	-2.8	-1.8	-1.2
Major Depression (MDD)	1.7	2.1	6.3	-1.1	1.1	1.6	-1.4	-1.2	-1.2	1.4	-1.0	0.0	-2.4	-1.4	-0.9	-0.9	-2.5	-1.4
Reaction Time	4.5	8.6	23.3	4.8	-3.9	-3.0	2.9	-1.4	4.0	-3.8	4.2	2.4	1.7	-0.1	-1.0	3.2	0.1	-1.5
Verbal and Numeric Reasoning (VNR)	3.2	7.7	19.1	-4.4	2.9	3.7	-2.8	1.4	-3.9	3.7	-3.8	-0.9	-2.6	-1.0	-0.9	-3.2	-1.6	1.0
Breast Cancer	10.0	24.1	48.6	-6.0	6.3	6.7	-6.0	0.8	-7.0	6.6	-6.6	-3.2	-3.8	-2.3	-1.0	-5.8	-1.5	0.4
Ovarian Cancer	1.5	2.0	4.7	0.3	-0.9	-0.9	1.4	1.8	0.9	-1.0	0.8	1.7	2.1	2.1	0.9	1.0	1.7	2.2
Prostate Cancer	0.9	1.3	3.2	-1.0	0.6	1.4	-0.7	-1.4	-1.0	1.2	-1.2	-1.3	-1.7	-0.8	-0.9	-0.2	-1.8	-0.4
Age at First Birth	0.4	0.5	1.8	0.5	0.0	-0.2	-0.2	1.4	0.4	-0.3	0.4	1.1	-0.2	-1.3	-1.2	-0.0	-1.1	-0.2
Bipolar Disorder (2011)	0.5	0.5	2.6	-0.3	-0.6	0.0	0.9	0.2	0.5	-0.5	0.7	-0.4	0.9	1.0	0.2	0.8	0.2	1.6
Body Mass Index (BMI) (2010)	10.8	14.8	27.9	-5.2	4.6	4.4	-4.4	1.2	-5.3	5.0	-5.1	-3.2	-3.2	-2.5	-1.8	-4.7	-1.3	-0.0
Coronary Artery Disease (CAD)	1.0	1.2	4.8	0.2	0.1	-0.4	-0.4	-1.3	0.4	-0.1	0.7	0.1	-1.9	-1.2	-0.9	0.4	-2.1	-2.2
Crohns Disease (2012)	4.5	7.2	25.4	-4.4	1.7	3.0	-2.0	-1.0	-3.9	2.9	-3.3	-5.0	-2.5	0.1	0.0	-2.1	-1.1	0.0
Mean Putamen Volume	0.1	0.2	0.6	0.1	-0.2	0.1	0.3	-0.1	0.2	-0.4	0.2	0.7	0.5	0.6	0.6	0.4	0.2	0.2
Fasting Glucose	1.3	1.5	7.6	0.5	0.6	0.1	-1.1	1.3	-0.9	0.7	-1.2	-0.0	-0.8	-2.8	-1.2	-0.9	-1.0	-2.2
HbA1C	0.8	0.9	5.2	-1.8	0.2	1.0	-0.1	-0.3	-1.2	0.7	-0.7	-2.3	-0.4	-0.1	0.8	0.0	-0.1	0.0
HDL Cholesterol	2.3	3.8	10.4	3.2	-1.6	-2.9	1.5	0.1	2.4	-2.4	2.1	1.2	2.4	0.5	1.0	1.1	2.8	0.0
LDL Cholesterol	0.1	0.2	0.6	-0.4	0.4	-0.2	-0.4	0.0	-0.5	0.3	-0.0	-0.4	-0.3	-0.8	0.1	-0.2	0.5	-0.6
Lupus	1.2	1.8	6.5	0.6	-0.5	-1.6	1.0	1.4	1.0	-1.0	1.0	0.5	2.1	1.3	1.2	0.7	2.5	1.8
Neuroticism (2016)	0.5	0.7	1.6	1.1	-0.4	-0.9	0.9	-0.8	1.1	-1.1	0.8	1.3	0.5	0.9	0.7	0.6	-0.2	0.0
Primary Biliary Cirrhosis	2.6	3.8	8.5	-2.9	2.0	2.2	-1.7	-0.5	-2.8	2.5	-2.6	-2.0	-1.5	1.2	1.4	-2.1	-0.4	1.1
Rheumatoid Arthritis	1.0	1.4	3.0	-1.0	1.0	0.9	-1.6	-0.1	-1.5	1.1	-1.2	-1.7	-1.0	-1.7	-0.5	-1.2	-0.4	-1.2
Schizophrenia (2014)	0.1	0.1	0.8	0.2	0.3	-0.0	0.1	0.5	0.4	-0.0	0.4	0.2	0.4	0.5	-0.9	-0.1	-0.1	0.1
Triglycerides	0.3	0.5	1.3	-0.4	-0.3	-0.4	1.1	-0.4	0.3	-0.3	0.2	-0.5	0.7	0.9	1.1	1.1	0.7	0.9
Type 2 Diabetes (T2D) (2012)	0.7	0.8	4.8	0.2	-0.3	0.3	0.8	1.1	0.1	-0.3	0.2	2.2	1.6	0.5	-0.4	0.2	1.3	0.8
Ulcerative Colitis	3.9	5.7	10.1	-3.1	2.6	2.6	-2.9	-0.1	-3.1	3.1	-3.2	-2.3	-2.4	-1.2	-1.0	-2.7	-1.1	-1.4
Blood Eosinophil Count	1.2	9.5	22.2	-4.7	3.3	4.2	-2.7	-0.4	-4.2	4.5	-4.2	-2.3	-3.2	0.6	0.3	-3.0	-1.8	1.2
Blood Platelet Count	0.4	4.1	8.5	-0.5	2.4	1.7	-2.9	1.4	-2.1	2.0	-2.0	1.6	-2.2	-2.4	-2.3	-2.7	-1.8	-0.2
Blood Red Count	0.4	4.1	18.1	-2.2	-0.1	1.4	2.2	-2.5	-0.3	0.5	-0.7	0.2	0.9	4.3	3.5	1.6	0.6	2.8
Blood White Count	1.3	9.4	23.8	-4.9	3.2	4.2	-1.9	-2.2	-3.9	3.9	-3.9	-3.9	-2.2	2.1	0.9	-2.2	-0.9	1.9
Heel T-Score	1.0	7.8	27.2	1.2	2.9	1.0	-4.4	3.4	-1.6	1.9	-2.1	2.0	-0.5	-5.2	-3.7	-3.9	0.1	-2.3
BMI	30.6	177.4	346.0	-18.4	16.2	16.7	-15.2	5.2	-18.6	18.0	-18.0	-10.5	-9.4	-5.3	-3.9	-16.3	-3.4	3.3
Height	15.5	298.2	561.7	17.6	-20.7	-19.2	23.7	-8.4	22.2	-20.7	22.6	10.6	14.8	14.7	14.1	20.8	9.1	6.3
Waist Hip Ratio (WHR)	3.8	17.2	56.2	0.1	-3.2	-2.2	5.3	-3.0	2.7	-2.3	2.6	2.5	4.4	7.5	7.0	4.1	4.5	4.3
Systolic Blood Pressure	9.0	45.0	85.4	5.6	-7.7	-6.6	9.2	-3.7	8.1	-7.3	7.2	5.0	6.1	8.0	6.7	8.4	3.7	4.1
Smoking Status	3.3	7.9	14.8	-3.3	3.6	3.2	-3.2	0.5	-3.8	3.7	-3.4	-3.6	-2.1	-1.3	-1.2	-3.6	-0.6	-0.1
Allergy or Eczema	0.8	2.1	7.3	-1.3	1.7	1.0	-1.2	2.7	-1.5	0.9	-1.1	-0.8	1.2	-0.2	-0.9	-2.1	1.7	1.4
Cardiovascular Disease	2.5	8.3	32.4	-1.2	-1.3	-0.5	2.9	-0.8	1.1	-0.5	0.3	1.1	3.0	5.7	5.1	1.7	2.9	5.6
Hypothyroidism (self reported)	1.6	3.6	11.4	-2.6	1.7	2.5	-1.6	-0.6	-2.5	2.2	-2.4	-3.4	-1.8	0.1	0.2	-1.2	-1.5	0.2
Respiratory disease	0.6	1.2	2.3	-0.9	1.5	1.1	-1.4	1.2	-1.0	1.3	-1.3	1.0	-0.8	-1.0	-1.3	-1.4	-0.5	-0.1
Type 2 Diabetes (T2D) (2018)	1.2	2.2	7.4	-2.7	0.8	1.9	-0.8	2.2	-1.6	1.6	-1.8	-0.1	0.6	0.5	0.5	-1.4	0.3	2.1
Lung FEV1/FVC ratio	5.3	26.8	55.5	-6.7	6.0	6.6	-5.7	-0.4	-7.5	7.2	-7.0	-4.3	-5.0	-1.4	-1.9	-5.8	-2.4	0.2
Lung FVC	2.0	10.3	16.9	3.8	-2.8	-2.8	3.4	-1.0	3.6	-3.5	3.6	2.8	4.1	3.9	2.1	3.0	3.8	2.6
Neuroticism	1.0	2.5	9.7	-1.8	2.1	1.0	-1.6	3.1	-1.6	1.6	-1.9	0.7	0.3	0.4	0.3	-2.5	0.4	1.2
Chronotype (morning person)	4.2	9.7	19.1	3.7	-3.9	-3.5	4.0	-2.3	4.2	-4.0	4.0	1.8	2.2	2.2	0.8	4.4	0.7	-0.2
Hair Pigment	0.5	15.4	42.0	-6.5	5.0	4.0	-4.1	-0.7	-5.0	5.2	-4.7	-1.9	-4.5	-1.1	0.8	-4.8	-2.6	-0.2
Tanning	1.8	21.6	46.1	5.3	-5.7	-4.2	5.6	-6.6	5.8	-5.4	6.4	1.6	-0.1	1.2	1.4	6.8	-2.0	-3.2
Hand grip strength (left)	12.6	33.3	61.5	6.7	-6.1	-7.3	7.0	-0.0	7.6	-7.8	7.8	2.7	6.1	3.5	4.0	6.4	4.2	1.7
Number of treatments/medications taken	1.4	2.5	9.5	-1.4	0.4	-0.5	0.2	-0.4	-0.5	0.7	-0.8	-2.2	1.8	2.3	2.5	-0.5	3.1	2.1
Average weekly spirits intake	0.9	1.1	7.8	-1.5	-0.6	-0.2	-0.3	-0.4	-0.4	-0.1	0.5	-2.8	-1.2	-0.8	0.1	0.5	-1.5	-0.9
Sensitivity / hurt feelings	2.3	3.9	6.8	-2.1	2.0	2.0	-2.2	1.6	-2.2	2.2	-2.2	-0.5	-1.8	-1.9	-2.6	-2.4	-1.8	-0.5
Frequency of depressed mood in last 2 weeks	2.0	2.9	6.8	-2.6	1.9	1.6	-0.9	1.3	-2.0	2.1	-2.5	-0.2	0.6	0.6	1.7	-2.0	1.4	1.9
Hearing difficulty/problems: Yes	2.3	3.5	8.6	-2.4	2.9	1.8	-1.8	1.6	-2.5	2.6	-2.7	-1.0	-0.3	0.0	-0.7	-2.3	0.7	1.0
Relative age of first facial hair	1.2	2.4	7.0	-0.9	2.2	1.1	-2.6	0.7	-2.2	1.7	-2.2	-0.8	-0.9	-0.6	0.7	-2.6	0.6	-0.4
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	4.1	-0.4	-0.0	-0.8	0.4	-1.9	0.2	-0.0	0.1	-2.0	0.2	1.3	1.7	0.4	1.0	0.7
Ever used hormone-replacement therapy (HRT)	1.1	1.4	3.6	1.0	-1.0	-1.3	1.2	-0.0	1.1	-1.3	1.5	0.5	1.4	1.2	1.9	1.0	1.4	0.8
Ever had hysterectomy (womb removed)	0.4	0.4	2.2	0.3	-0.3	-0.2	0.5	-0.7	0.5	-0.4	0.5	0.2	0.7	1.2	1.5	0.4	0.8	0.4
Systolic blood pressure, automated reading	4.5	13.2	32.8	1.4	-3.3	-2.4	5.0	-1.2	3.5	-3.0	2.8	3.1	4.2	5.7	4.0	3.8	3.2	4.7
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	7.6	-1.4	0.9	1.5	-1.4	2.8	-1.7	1.7	-1.6	0.5	0.2	-0.5	-0.8	-1.9	0.6	1.3
Angina	2.8	3.7	11.5	-2.3	1.8	1.9	-1.8	-1.7	-2.3	1.8	-1.5	-3.4	-2.6	-1.3	-0.4	-1.3	-2.0	-0.9
Medication for hormone replacement therapy	2.1	2.4	6.8	1.9	-1.0	-2.3	0.8	1.1	1.6	-1.9	1.6	-0.6	2.5	0.6	0.4	0.8	2.6	0.2
Vitamin and mineral supplements	1.6	2.2	5.6	-2.4	1.3	2.4	-1.2	0.6	-1.9	1.8	-2.1	0.5	-1.0	-0.8	-1.0	-1.3	-1.4	0.2
Supplements: Zinc	0.8	0.9	3.0	1.3	-0.5	-1.7	0.1	0.7	1.1	-0.8	1.1	1.1	-0.3	-0.8	-1.1	-0.1	-0.2	-1.1
Medication: Co-codamol	1.2	1.3	3.5	-1.4	1.4	0.9	-1.3	-1.1	-1.1	1.6	-1.2	-0.9	-1.9	-0.3	-0.9	-1.1	-0.8	0.3
Medication: Metformin	2.8	4.0	10.7	-3.3	1.6	2.9	-2.0	2.7	-2.6	2.4	-2.7	-0.3	-0.3	-0.5	-0.8	-2.0	-0.4	1.6
Diabetes (father)	1.0	1.3	3.8	1.0	-1.2	-0.9	1.1	-0.7	1.1	-1.2	0.7	-0.2	1.5	0.4	1.9	1.5	1.4	0.8
Diabetes (mother)	0.4	0.5	2.0	0.4	-0.5	-0.7	0.6	0.5	0.8	-0.4	0.3	1.4	0.5	-0.3	-1.0	0.9	0.2	0.6
Severe depression (siblings)	1.9	2.1	3.4	-1.8	1.4	1.6	-1.3	-0.0	-1.7	1.8	-1.7	-1.9	-1.6	-1.3	-1.4	-1.0	-1.2	-0.4
Pack years adult smoking proportion	3.0	4.6	10.8	-2.9	2.3	2.7	-2.2	0.9	-2.9	2.6	-2.5	-3.3	-1.2	-0.8	-1.0	-2.4	-0.9	0.6
Impedance of leg (right)	4.7	22.9	44.6	6.4	-5.4	-5.2	6.1	-3.0	6.7	-6.1	6.0	4.8	3.6	2.7	1.5	5.9	0.8	-0.9
Leg fat-free mass (left)	1.0	5.2	15.6	-4.0	1.4	2.1	-0.2	1.0	-2.6	2.4	-1.7	-2.7	0.1	1.7	3.2	-1.4	1.7	3.9
Trunk fat percentage	17.7	70.9	166.4	-12.9	9.9	11.3	-8.2	2.4	-11.9	11.7	-11.6	-6.4	-4.9	-0.9	-0.2	-9.9	-1.3	4.2
Hand grip strength (right)	10.4	28.4	58.2	6.1	-5.7	-6.7	6.7	0.3	6.8	-7.3	7.6	2.2	5.4	3.0	3.4	6.1	3.8	1.6
Townsend deprivation index at recruitment	0.6	0.8	3.1	-1.8	0.8	1.1	-0.6	0.6	-1.2	1.3	-1.3	-0.1	-0.1	0.6	0.2	-1.0	0.0	0.8
Current tobacco smoking	1.4	2.2	7.0	-1.9	1.6	2.0	-1.2	-0.7	-1.9	1.9	-1.6	-2.6	-1.4	-0.1	-0.2	-1.2	-1.1	-0.1
Average weekly fortified wine intake	0.5	0.6	1.5	-0.8	0.6	-0.5	-0.8	1.2	-0.6	0.6	-0.6	-0.9	-0.1	-1.0	-1.2	-0.7	0.5	-0.8
Maternal smoking around birth	0.3	0.4	1.5	-0.6	0.6	0.6	-0.4	1.2	-0.6	0.4	-0.4	0.2	0.3	0.1	0.9	-0.7	-0.1	0.8
Fed-up feelings	1.5	2.8	8.4	-1.5	2.2	1.5	-2.0	2.9	-2.1	1.8	-2.0	0.4	0.2	-0.9	-0.7	-2.5	0.8	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	4.6	-1.2	1.0	0.6	-0.6	2.2	-1.0	1.0	-1.3	0.2	1.0	-0.4	-0.1	-1.3	1.1	1.6
Relative age voice broke	1.2	1.9	5.4	-0.2	2.1	1.1	-1.8	0.5	-1.8	1.4	-2.0	0.1	0.4	-0.0	0.7	-2.3	1.9	0.1
Taking other prescription medications	0.8	1.3	4.1	-2.0	1.2	1.0	-0.9	-0.0	-1.3	1.6	-1.8	-1.3	-0.3	0.3	0.6	-1.1	0.3	1.1
Age when periods started (menarche)	7.2	17.2	37.4	6.1	-4.2	-4.6	4.2	0.1	5.3	-5.6	5.3	4.6	4.8	2.2	1.1	3.7	3.4	0.6
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.5	0.3	-1.2	-0.3	1.8	-0.7	0.9	-1.0	1.5	0.7	1.1	1.9	1.3	1.6	0.9	1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	4.1	-0.3	1.0	-0.2	-1.8	1.4	-0.7	0.7	-1.2	-1.4	-0.2	-2.0	-0.9	-1.9	0.0	-0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	2.6	-0.2	-0.1	0.1	0.1	1.6	0.0	-0.1	-0.0	0.5	0.2	-0.8	-0.6	0.2	-0.6	0.1
Qualifications: CSEs or equivalent	0.9	1.2	5.0	-0.5	0.9	1.5	-0.4	-0.8	-0.5	1.0	-0.5	0.0	-0.9	-1.8	-2.2	0.2	-1.9	-0.4
Serious illness, injury or assault to yourself	0.4	0.5	1.7	-0.0	-0.6	-1.3	-0.1	-0.7	0.4	-0.2	0.5	-1.3	0.0	-0.3	1.3	0.2	0.8	-0.3
High blood pressure	3.7	10.2	39.7	-1.0	-1.6	-0.5	3.5	-0.8	1.5	-0.8	0.5	1.9	3.6	5.9	5.4	1.9	3.1	6.3
Hayfever, allergic rhinitis or eczema	0.6	1.2	5.2	-0.5	1.2	0.3	-0.9	2.3	-0.9	0.3	-0.6	-1.1	1.2	0.2	-0.9	-1.6	1.6	0.8
Multivitamins +/- minerals	2.0	2.5	6.9	2.0	-1.8	-2.6	1.4	-0.2	2.0	-2.2	2.3	-0.5	1.1	0.8	1.4	1.5	1.3	-0.1
Stomach or abdominal pain in last month	0.2	0.2	1.1	-0.2	-0.4	-0.4	0.4	1.1	0.0	-0.5	0.6	-0.1	0.3	-0.6	-0.7	0.2	0.3	0.1
Supplements: Glucosamine	0.4	0.6	2.2	-0.1	-0.3	-0.0	0.3	-0.6	-0.0	-0.2	0.5	-1.4	0.6	0.9	1.5	0.3	1.3	0.8
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	3.0	1.7	-0.8	-0.8	0.3	-1.3	1.3	-0.8	1.0	1.2	0.2	0.1	-0.5	0.9	0.1	-0.5
Medication: Atenolol	2.9	3.6	14.9	-1.8	0.8	1.3	0.0	0.6	-1.1	1.0	-1.5	-0.1	1.9	2.9	3.1	-0.9	2.5	3.9
Medication: Levothyroxine sodium	0.7	1.1	3.9	-1.3	1.0	1.3	-0.6	-0.8	-1.3	1.3	-1.4	-2.0	-1.0	0.1	0.6	-0.6	-0.7	-0.2
Sitting height	15.8	112.0	234.1	14.5	-13.3	-14.1	12.1	-2.0	15.0	-14.2	15.3	7.4	7.1	2.4	2.8	12.4	2.6	-1.8
Chronic bronchitis/emphysema (father)	0.5	0.6	3.2	0.2	-0.1	-0.1	-0.0	0.6	0.4	-0.1	0.3	1.6	-0.6	-0.7	-1.8	-0.3	-1.3	-0.6
High blood pressure (mother)	0.8	1.1	4.5	-0.2	-0.6	-0.1	1.5	-1.5	0.8	-0.2	0.1	0.2	0.6	2.1	1.0	1.2	0.5	1.7
Body mass index (BMI)	26.6	113.1	228.0	-15.1	12.7	13.6	-11.9	4.2	-15.0	14.4	-14.5	-8.6	-7.1	-3.7	-2.1	-12.7	-2.4	3.5
Impedance of leg (left)	4.6	22.1	44.2	6.4	-5.3	-5.2	5.9	-3.1	6.7	-6.0	6.1	4.6	3.3	2.4	1.1	5.9	0.7	-1.0
Leg predicted mass (left)	1.0	5.0	15.2	-3.9	1.3	2.1	-0.2	0.9	-2.5	2.3	-1.6	-2.8	0.1	1.7	3.2	-1.4	1.6	3.8
Trunk fat mass	12.3	52.9	134.6	-11.6	8.4	9.6	-6.5	2.3	-10.3	10.1	-9.8	-5.9	-3.6	0.0	1.0	-8.4	-0.1	5.0
Waist circumference	13.5	49.5	136.9	-11.7	7.9	9.2	-6.0	1.7	-9.9	9.8	-9.5	-5.9	-3.5	0.7	1.9	-7.7	-0.0	4.9
Number of incorrect matches in round	4.0	6.7	13.2	3.3	-3.3	-3.4	3.2	-0.2	3.6	-3.6	3.2	1.8	2.5	1.4	0.5	2.8	1.1	0.2
Past tobacco smoking	4.9	9.0	19.5	3.7	-4.2	-3.4	3.2	-1.6	4.1	-4.3	3.9	1.9	1.2	0.7	0.5	4.4	-0.7	-1.7
Alcohol usually taken with meals	0.8	1.3	3.7	1.1	-1.2	-1.1	1.9	-1.7	1.3	-1.2	1.5	-0.1	0.0	0.6	0.9	1.8	-0.3	-0.2
Nervous feelings	0.7	1.2	4.7	1.4	-0.4	-2.2	0.4	1.5	1.6	-1.3	1.3	0.5	0.6	-0.9	-1.3	0.3	0.1	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.5	-0.6	0.2	0.4	0.9	-0.7	-0.1	0.4	-0.4	1.2	0.6	0.8	0.7	0.1	0.9	0.9
Hearing difficulty/problems with background noise	1.2	2.0	4.7	-1.4	1.6	1.3	-0.3	2.2	-1.4	1.6	-1.9	0.3	1.2	0.6	-0.5	-1.3	1.6	2.0
Hair/balding pattern: Pattern 2	0.3	0.4	1.8	-0.2	0.3	1.1	-0.5	-1.3	-0.6	0.6	-0.3	-0.0	-0.6	0.1	0.3	0.3	-0.6	-1.0
Had menopause	0.8	1.0	3.0	0.8	-1.0	-0.8	1.1	-0.9	1.0	-0.9	0.7	0.5	1.2	1.7	1.4	0.9	1.0	0.4
Had other major operations	0.4	0.5	2.8	-0.9	0.1	0.1	-0.5	-0.1	-0.4	0.7	-0.5	-1.7	0.4	0.5	0.6	-0.5	0.9	1.1
Forced vital capacity (FVC)	15.6	60.0	96.2	8.6	-8.5	-8.4	9.8	-2.6	9.7	-9.3	9.7	5.3	8.0	7.1	6.3	8.7	6.0	3.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	2.2	-0.4	0.7	0.5	-1.0	-0.0	-0.3	0.6	-0.8	-0.5	-0.2	-1.5	-0.3	-0.9	-0.4	0.0
Ever unenthusiastic/disinterested for a whole week	1.6	2.0	4.1	-1.7	1.6	1.8	-1.5	1.7	-1.6	1.5	-1.6	0.2	-0.7	-1.6	-0.7	-2.0	-1.1	-0.3
Qualifications: None of the above	0.1	0.2	0.8	0.5	0.7	-0.3	-0.9	-0.3	0.1	0.3	-0.1	-0.0	0.1	-0.3	-0.3	-0.8	0.6	-0.4
Financial difficulties in last 2 years	0.5	0.7	2.0	-1.1	1.0	0.8	-0.9	1.2	-1.2	0.6	-0.8	-1.4	0.3	-0.2	-0.5	-0.6	0.7	0.0
Mouth/teeth dental problems	2.8	4.4	9.5	3.0	-2.6	-2.4	2.2	-1.8	2.8	-3.0	3.1	0.1	0.3	-0.0	-0.1	2.7	-0.5	-1.5
Heart attack	0.9	1.1	6.1	0.4	-0.1	-0.3	-0.6	-1.8	-0.2	-0.2	0.5	-2.5	-1.2	-1.0	-0.3	0.0	-0.9	-1.8
Allergy	0.2	0.5	1.8	0.2	-0.9	-0.2	0.7	-1.3	0.6	-0.4	0.5	0.6	-0.1	0.5	1.4	1.0	-0.3	0.0
Pain all over the body in last month	1.4	1.5	5.7	0.5	-0.3	-0.6	1.1	0.7	0.7	-0.8	0.3	0.4	2.4	1.3	1.0	0.4	2.4	2.0
Diabetes (self-reported)	2.2	3.4	13.9	-2.7	1.4	1.9	-1.7	3.7	-2.0	1.7	-2.2	-0.6	0.9	-0.7	-0.9	-2.1	0.6	1.7
Hayfever/allergic rhinitis (self-reported)	1.7	2.2	7.4	0.1	-0.8	-1.6	1.6	2.2	1.0	-1.3	0.9	-0.6	2.7	1.4	0.4	0.5	2.3	1.8
Medication: Ramipril	2.3	2.9	11.8	-0.7	-0.8	-0.4	1.4	0.2	0.6	-0.6	0.2	-0.7	2.3	3.4	2.4	1.1	2.0	3.3
Medication: Simvastatin	1.0	1.5	4.4	-2.1	0.8	0.9	-0.7	0.6	-1.3	1.3	-1.2	-1.4	0.4	0.9	1.8	-0.9	1.0	1.9
Fluid intelligence score	3.0	6.2	13.0	-3.6	2.7	2.5	-3.1	2.4	-3.4	3.2	-3.3	-0.6	-1.8	-1.6	-0.8	-3.4	-0.5	0.5
Illnesses of siblings	1.5	2.0	4.5	2.1	-1.8	-1.4	1.1	0.3	1.6	-2.1	2.1	0.8	1.3	-0.6	-0.2	1.6	0.6	-1.7
Neuroticism score	1.6	3.3	6.8	-2.1	2.5	2.0	-1.7	2.6	-2.3	2.2	-2.3	0.3	-0.5	-0.4	-1.4	-2.6	-0.5	0.4
Weight	5.2	25.8	74.7	-8.6	5.4	6.4	-3.5	1.5	-7.0	6.9	-6.3	-4.8	-1.8	1.2	2.6	-5.3	1.1	5.3
Impedance of arm (right)	1.1	5.1	11.7	2.3	-2.9	-1.5	3.4	-1.6	2.9	-2.6	2.5	3.1	1.6	1.9	0.3	2.8	-0.2	-0.7
Arm fat percentage (right)	31.6	124.7	272.2	-16.5	13.1	14.8	-11.7	4.3	-15.9	15.1	-15.4	-8.6	-7.1	-3.0	-2.0	-13.2	-2.6	4.0
Trunk fat-free mass	2.6	14.7	33.2	1.3	-3.7	-3.4	5.1	-0.3	3.3	-3.3	4.1	-0.0	4.3	4.5	5.8	3.8	4.5	4.8
Hip circumference	11.4	49.1	114.5	-10.7	7.9	8.9	-7.2	2.8	-9.8	9.5	-9.1	-6.9	-4.6	-2.5	-0.7	-8.1	-1.6	2.7
Time employed in main current job	3.9	4.5	9.5	2.7	-2.4	-2.1	2.5	-3.1	2.8	-2.2	2.9	1.8	-0.0	0.8	1.1	2.5	-0.8	-1.4
Alcohol intake versus 10 years previously	0.2	0.3	0.8	-0.3	0.4	0.7	-0.3	-0.4	-0.5	0.4	-0.2	-0.5	-0.7	-0.4	-0.9	-0.4	-0.7	-0.4
Father’s age at death	0.3	0.4	1.5	1.0	-0.3	-0.7	0.5	-0.8	0.8	-0.7	0.3	0.2	-0.0	0.0	1.2	0.2	0.3	-0.6
Worrier / anxious feelings	1.9	3.6	7.3	2.6	-1.8	-2.7	1.9	1.1	2.5	-2.5	2.7	2.4	1.3	-0.1	-1.4	1.5	0.4	-0.9
Frequency of tiredness / lethargy in last 2 weeks	2.4	3.9	9.0	-3.0	2.2	3.0	-1.7	1.0	-2.6	2.7	-2.9	-0.4	-0.6	-0.3	-1.4	-2.1	-0.7	1.3
Falls in the last year	0.5	0.7	2.1	-1.5	0.2	0.4	0.4	-0.5	-0.5	0.6	-0.5	-0.7	-0.6	1.4	1.4	-0.2	-0.2	1.4
Hair/balding pattern: Pattern 3	0.7	1.1	3.5	1.2	-0.8	-0.8	1.5	1.1	1.3	-1.4	0.8	0.6	1.9	0.4	-0.5	0.9	0.9	0.5
Number of live births	0.3	0.4	1.0	-0.2	-0.9	-0.2	0.8	-0.6	0.5	-0.4	0.3	-0.4	-0.3	0.9	0.5	0.9	-0.5	1.0
Forced expiratory volume in 1-second (FEV1)	10.6	35.8	56.9	6.3	-6.8	-6.5	7.5	-2.4	7.2	-7.0	7.4	3.5	6.0	6.2	5.2	6.9	4.8	3.0
Pulse rate	0.9	1.6	6.6	0.4	-0.9	-1.4	0.6	2.6	0.9	-0.6	0.4	1.6	1.9	0.7	-0.4	0.4	2.2	0.9
Happiness	0.2	0.3	1.1	-0.8	0.4	0.8	-0.3	-0.5	-0.7	1.0	-0.6	-0.5	-0.4	0.2	-0.1	-0.1	0.0	0.1
Noisy workplace	0.3	0.3	0.9	1.0	-0.4	0.2	0.6	-0.7	0.6	-0.5	0.5	0.8	0.7	0.2	-0.2	0.9	-0.0	0.4
Qualifications: A levels/AS levels or equivalent	0.9	2.0	4.7	0.1	-2.2	-2.1	2.2	0.3	1.7	-1.9	1.8	-0.1	0.8	1.3	1.0	1.7	0.3	0.8
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	3.5	-0.6	1.6	0.8	-1.9	0.1	-1.3	1.2	-0.9	-1.0	-0.9	-1.8	-1.7	-1.6	-0.1	-1.6
Mouth/teeth dental problems: Dentures	4.9	8.3	20.6	-4.5	3.3	2.9	-3.3	0.8	-3.8	4.0	-4.3	-2.1	-2.1	-0.8	-0.1	-3.6	-1.1	0.9
Asthma	0.5	1.0	3.3	-1.8	1.3	1.1	-0.7	0.7	-1.1	1.4	-1.2	0.2	-1.0	-0.2	-0.4	-1.0	-0.7	1.0
Medication: Ibuprofen (e.g. Nurofen)	2.5	3.2	9.5	0.4	-1.0	-0.8	2.1	-0.0	1.1	-1.2	1.3	-0.2	2.9	2.8	1.8	1.6	3.1	2.5
Medication: Cholesterol lowering	0.6	0.9	3.7	-0.5	0.4	-0.2	-0.5	0.2	-0.6	0.3	-0.4	-1.9	1.0	0.9	1.6	-0.4	1.8	0.9
Depression (self-reported)	0.2	0.3	1.9	0.3	0.2	0.1	-0.2	-0.2	0.2	-0.0	-0.3	1.4	0.8	0.2	0.7	-0.0	0.6	0.8
Medication: Lansoprazole	0.6	0.7	3.0	-1.5	0.3	0.6	0.0	-1.1	-0.8	0.6	-0.6	-1.7	-0.3	-0.2	1.2	0.3	-0.3	-0.2
Prospective memory result	0.2	0.3	0.7	-0.0	-0.7	-0.1	0.7	-0.9	0.5	-0.4	0.5	-0.1	0.3	0.5	-0.3	0.9	-0.0	-0.6
Lung cancer (father)	0.4	0.5	1.5	0.2	-0.8	-0.8	0.4	-0.8	0.6	-0.7	1.2	-0.4	-0.3	0.1	1.0	0.7	-0.4	-0.7
Illnesses of mother	1.0	1.2	4.8	1.5	-0.2	-0.8	-0.6	1.8	0.2	-1.0	0.9	0.4	0.0	-2.2	-1.5	-0.1	-0.3	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	7.5	23.9	40.1	4.9	-5.4	-5.0	6.3	-2.4	5.8	-5.5	6.2	2.9	4.6	5.3	4.4	5.8	3.6	3.0
Pulse wave Arterial Stiffness index	0.2	0.2	1.1	-0.1	0.1	0.1	0.6	0.3	0.2	-0.0	0.5	0.3	0.1	-0.7	-0.6	0.4	-0.3	1.1
Impedance of arm (left)	1.0	4.9	11.0	2.2	-2.7	-1.7	3.3	-2.1	2.8	-2.5	2.5	2.4	1.4	2.5	1.2	2.6	-0.1	-0.3
Arm fat mass (right)	19.8	81.5	196.0	-14.0	10.3	11.9	-8.8	3.6	-12.9	12.3	-12.3	-7.7	-5.1	-1.2	-0.1	-10.4	-1.1	5.0
Trunk predicted mass	2.6	14.8	33.9	1.2	-3.6	-3.3	5.1	-0.2	3.3	-3.3	4.1	-0.1	4.4	4.5	5.8	3.8	4.5	4.9
Standing height	15.7	156.2	292.4	12.5	-14.7	-14.2	17.1	-5.3	15.9	-14.9	16.5	7.1	11.2	10.6	10.5	14.9	7.6	4.7
Length of working week for main job	0.2	0.2	1.2	-0.3	-0.5	0.2	0.2	0.7	-0.2	-0.3	0.2	-0.1	0.8	1.1	0.8	0.1	0.3	0.4
Exposure to tobacco smoke at home	0.4	0.5	2.4	0.5	-0.8	-0.1	0.7	-1.6	0.6	-0.3	0.7	0.4	-0.5	0.1	-0.0	0.9	-0.7	-0.7
Breastfed as a baby	1.1	1.4	2.6	1.1	-1.4	-0.9	1.4	-1.1	1.6	-1.3	1.6	1.3	0.1	-0.5	-0.3	1.3	-0.7	-1.5
Tense / ‘highly strung’	0.5	0.8	2.4	1.0	-0.6	-1.0	1.6	0.1	1.3	-0.9	1.0	1.4	0.2	0.8	-0.8	0.8	-0.5	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.9	2.9	6.7	-2.3	2.5	1.5	-1.9	2.0	-1.9	2.0	-2.2	1.1	-0.3	-0.4	-1.0	-2.6	-0.0	0.7
Hair/balding pattern: Pattern 4	0.6	1.4	3.5	-1.9	1.2	1.5	-1.1	0.2	-1.4	1.6	-1.6	-1.2	-0.9	-0.4	-0.9	-1.0	-1.0	0.3
Birth weight of first child	1.5	2.7	5.5	1.6	-1.4	-1.2	1.9	0.3	1.7	-1.6	1.7	1.9	2.3	1.5	1.8	1.3	2.0	1.5
Peak expiratory flow (PEF)	4.6	10.7	16.5	3.1	-3.5	-4.0	4.0	-1.6	4.0	-3.7	4.1	1.6	3.1	3.6	3.3	3.6	2.9	1.4
Pulse wave reflection index	0.3	0.3	0.9	-0.5	0.7	1.0	0.1	-0.6	-0.5	0.4	-0.2	-0.5	-0.5	-0.9	-0.6	-0.2	-0.6	0.3
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.2	-0.3	0.6	1.1	-0.1	-0.5	-0.8	0.4	-0.3	0.1	-0.1	0.2	0.2	-0.4	0.3	0.4
Loud music exposure frequency	0.8	0.8	3.5	1.9	-0.5	-1.2	0.9	-0.4	1.1	-1.2	1.0	0.4	1.0	0.6	-0.0	0.7	0.8	-0.1
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	3.6	-0.3	-1.8	-0.3	1.9	-0.3	0.6	-1.0	1.0	-0.8	0.1	1.2	0.3	1.7	-0.8	0.9
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	1.7	-1.2	1.0	1.3	-0.7	1.3	-1.2	0.8	-0.9	1.0	0.1	0.1	0.3	-1.0	-0.2	0.3
Blood clot in the leg (DVT)	1.6	2.1	6.6	-0.3	0.4	0.6	-1.1	-1.5	-0.5	0.7	-0.3	-0.5	-2.5	-2.1	-1.5	-0.6	-2.6	-2.5
Medication: Paracetamol	0.6	1.0	5.2	-0.8	0.0	0.2	0.5	-0.3	-0.5	0.6	-0.5	-1.2	1.6	1.5	0.8	-0.1	2.3	1.2
Headache pain in last month	0.2	0.3	1.2	-0.7	-0.2	0.8	0.6	0.4	-0.5	0.3	-0.5	-0.2	0.1	0.7	-0.4	0.2	-0.0	1.1
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	8.3	0.3	0.3	0.6	-0.9	0.6	-0.3	0.3	-0.3	1.2	-1.4	-2.1	-2.9	-0.6	-2.0	-2.0
Glaucoma (self-reported)	0.4	0.4	1.7	-0.3	0.5	0.1	-0.7	0.5	-0.4	0.3	-0.7	-0.2	0.3	1.1	0.2	-0.8	0.9	1.3
Gout (self-reported)	0.2	0.3	0.9	0.3	0.5	-0.2	-1.0	0.0	0.1	0.4	0.1	0.9	-0.1	-0.4	-0.9	-0.8	0.2	-0.7
Hypothyroidism/myxoedema (self-reported)	1.2	2.4	9.3	-1.4	1.5	1.9	-1.5	-0.9	-1.8	1.6	-1.6	-3.0	-1.8	-0.8	-0.5	-0.9	-1.6	-0.8
Medication: Amlodipine	1.2	1.6	9.1	-1.5	0.6	1.0	0.5	0.6	-0.7	0.6	-0.7	0.5	1.0	2.1	1.6	-0.4	1.1	3.0
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.9	0.6	-0.4	0.0	0.4	-0.6	0.6	-0.2	0.4	0.9	-0.3	0.6	-0.5	0.3	-0.6	-0.1
Birth weight	1.7	3.7	17.4	-1.1	0.4	-0.4	0.6	2.2	-0.2	0.2	-0.9	1.1	2.4	2.9	2.6	-1.1	2.7	4.2
Chronic bronchitis/emphysema (mother)	1.0	1.2	4.0	-0.4	0.0	-0.3	0.8	1.0	-0.0	-0.4	0.2	-0.7	1.5	2.0	1.6	-0.0	1.6	1.9
High blood pressure (siblings)	1.1	1.5	6.2	-0.1	-0.5	-0.9	1.4	-0.7	0.7	-0.1	0.0	-0.2	0.9	2.5	2.2	0.5	1.1	2.4
Forced vital capacity (FVC), Best measure	12.6	46.1	78.1	7.2	-7.6	-7.3	8.8	-2.7	8.5	-8.1	8.8	4.2	6.5	6.4	5.5	7.9	4.6	3.5
Body fat percentage	23.4	92.4	207.4	-14.4	11.5	12.7	-9.9	2.9	-13.5	13.2	-13.2	-7.3	-6.2	-2.0	-1.1	-11.4	-2.1	4.0
Leg fat percentage (right)	26.0	94.2	196.0	-14.0	11.9	12.4	-10.5	2.9	-13.5	13.3	-13.4	-7.2	-6.7	-2.9	-1.9	-11.7	-2.6	3.4
Arm fat-free mass (right)	1.2	6.2	23.4	-0.5	-1.3	-1.5	2.5	0.1	1.0	-1.0	1.8	-1.4	2.6	3.2	4.8	1.4	3.7	4.3
Exposure to tobacco smoke outside home	1.9	2.6	6.1	-2.4	1.5	2.4	-1.7	0.5	-2.5	2.0	-2.0	-1.6	-0.6	-0.2	0.9	-1.8	-0.3	1.3
Comparative body size at age 10	96.2	265.6	519.8	-22.8	19.5	21.3	-18.0	4.8	-22.6	22.0	-22.7	-10.3	-13.5	-6.2	-5.3	-18.8	-7.4	3.2
Number of full brothers	2.3	2.9	6.9	-1.4	2.4	1.7	-2.4	0.2	-2.2	2.4	-2.5	-1.1	-0.7	0.0	0.3	-2.6	1.1	0.6
Worry too long after embarrassment	1.3	2.2	4.7	-1.9	2.2	1.4	-1.5	1.9	-1.9	1.9	-2.1	0.0	-0.5	-0.6	-0.9	-2.0	0.2	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	3.0	-0.4	0.1	-1.0	-0.3	1.7	0.2	-0.6	0.1	-0.3	0.7	-0.7	0.1	-0.4	0.6	-0.8
Wheeze or whistling in the chest in last year	0.7	1.2	4.1	-1.9	1.2	1.6	-0.2	0.3	-1.2	1.4	-1.1	-1.2	-0.1	0.3	0.2	-0.6	0.2	2.0
Number of children fathered	0.7	0.8	2.4	0.7	-0.7	-0.6	1.0	-1.5	1.1	-1.0	1.6	0.6	0.1	0.5	0.2	1.4	-0.2	0.6
Reason for reducing amount of alcohol drunk: Health precaution	4.5	5.3	10.4	2.6	-2.7	-2.8	3.2	-1.4	3.1	-2.9	2.8	1.6	1.8	1.1	1.4	3.1	1.2	0.4
Age at first live birth	1.4	2.5	6.7	2.2	-1.4	-1.9	1.2	1.3	2.0	-1.8	2.0	2.6	1.4	-0.6	-1.2	1.1	0.9	-0.9
Pulse wave peak to peak time	0.6	0.8	1.8	1.0	-1.1	-1.1	0.6	-0.5	0.9	-1.0	0.7	0.3	0.7	1.3	1.3	0.5	0.8	-0.7
Health satisfaction	0.7	0.9	2.5	-1.2	1.2	0.8	-0.7	0.7	-0.8	0.9	-0.9	0.0	0.6	0.8	1.1	-1.5	0.4	1.6
Shortness of breath walking on level ground	0.3	0.3	1.0	-0.4	0.5	0.5	0.1	-0.7	-0.4	0.5	-0.6	-1.0	-0.0	1.0	0.7	-0.2	0.0	0.9
Qualifications: College or University degree	0.6	1.8	3.5	-0.1	-1.1	-1.5	1.7	1.5	1.0	-1.4	0.8	0.2	1.8	1.6	1.7	0.9	1.9	1.6
Eye problems/disorders: None of the above	2.5	2.9	6.4	2.5	-1.6	-0.9	1.1	-2.0	2.1	-1.8	2.1	0.7	-0.5	-1.2	-1.2	2.3	-1.7	-2.2
Mouth/teeth dental problems: Loose teeth	5.0	6.0	15.0	-2.8	3.0	1.9	-2.7	3.9	-3.0	2.4	-3.0	-1.6	0.7	-0.9	-1.1	-3.5	1.5	1.8
Emphysema/chronic bronchitis	0.3	0.4	1.9	1.1	-0.4	-0.2	0.5	-1.4	0.4	-0.2	0.3	0.0	0.2	-0.2	-0.6	0.7	0.3	-0.8
Medication for pain relief, constipation, heartburn	1.5	2.6	10.1	0.4	0.5	0.5	-1.3	0.6	-0.2	0.2	-0.2	1.1	-2.5	-2.5	-3.0	-0.6	-3.2	-1.9
Neck or shoulder pain in last month	0.9	1.3	4.7	-0.9	0.7	1.2	-1.0	-0.8	-0.9	0.8	-0.8	-1.5	-1.8	-1.4	-0.6	-0.6	-2.2	-1.1
Medication: Blood pressure	2.2	3.9	18.3	-0.4	-0.8	-0.6	1.7	-1.1	0.9	-0.8	0.7	-0.4	2.3	3.1	4.3	1.1	2.3	3.4
Angina (self-reported)	3.6	4.7	12.5	-2.7	2.1	2.2	-2.2	-1.4	-2.6	2.2	-1.9	-3.5	-2.8	-1.7	-0.6	-1.7	-2.2	-1.1
Migraine (self-reported)	1.7	2.1	3.9	-2.0	1.8	1.5	-1.4	-0.1	-1.6	1.8	-1.6	-1.2	-1.9	-1.6	-0.4	-1.3	-1.5	-0.1
Medication: Ibuprofen	2.1	2.5	8.3	-0.1	-0.6	-0.9	1.6	-0.5	0.8	-0.8	1.0	-1.2	2.3	2.4	2.1	1.3	2.9	2.2
Medication: Allopurinol	0.4	0.5	2.1	0.1	1.0	-0.2	-1.2	0.6	-0.1	0.5	-0.3	1.3	-0.0	-0.6	0.0	-1.4	0.5	-0.3
Medication: Omeprazole	3.0	3.6	14.0	0.5	-0.8	-1.7	1.5	-0.5	1.3	-0.9	0.8	1.6	2.4	2.8	3.7	0.6	2.7	2.5
Medication: Seretide 50 evohaler	0.1	0.1	0.4	-0.1	-0.3	0.6	-0.2	0.3	-0.2	-0.2	0.5	-0.2	-0.1	-0.2	-0.2	0.6	-0.4	-0.1
Mean time to correctly identify matches	3.2	6.0	17.1	4.1	-3.2	-2.7	2.1	-0.8	3.5	-3.2	3.5	2.6	1.3	-0.5	-0.8	2.2	-0.1	-1.4
Heart disease (mother)	1.8	2.2	15.2	-1.8	0.5	1.2	0.1	-3.9	-0.6	1.3	-0.6	-1.0	-1.4	1.5	2.2	0.1	-0.3	0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.0	2.3	5.4	1.7	-1.9	-1.1	1.4	0.0	1.9	-1.4	1.4	2.3	-0.2	-0.9	-1.8	1.6	-2.1	-1.3
Whole body fat mass	15.3	63.9	156.2	-12.5	9.3	10.5	-7.6	2.7	-11.3	11.0	-10.8	-6.8	-4.5	-0.9	0.3	-9.2	-0.9	4.7
Leg fat mass (right)	19.1	74.0	166.4	-12.9	10.4	11.1	-8.8	2.8	-12.1	11.8	-11.7	-7.0	-5.3	-1.9	-0.3	-10.2	-1.4	4.2
Arm predicted mass (right)	1.1	5.9	22.3	-0.5	-1.3	-1.4	2.5	0.1	1.0	-1.0	1.7	-1.4	2.5	3.1	4.7	1.5	3.4	4.3
Pulse rate, automated reading	2.1	6.7	19.4	1.6	-2.4	-2.6	2.6	3.1	2.3	-2.3	2.1	1.9	4.4	2.0	0.9	2.0	3.9	2.6
Alcohol intake frequency.	1.2	2.8	5.0	-2.2	2.0	1.7	-2.1	1.3	-1.6	1.8	-2.2	-0.8	-1.1	-1.6	-1.2	-2.2	-1.7	-0.5
Comparative height size at age 10	9.4	51.7	104.0	5.4	-7.8	-6.8	10.2	-3.2	8.3	-7.4	7.8	4.2	7.7	8.0	8.3	8.1	5.5	6.1
Number of full sisters	0.3	0.4	1.1	-0.4	0.8	0.5	-0.9	0.6	-0.4	0.7	-0.6	-0.4	0.3	-0.8	-1.0	-0.5	0.3	0.1
Suffer from ‘nerves’	0.4	0.6	4.5	0.1	0.1	-0.0	0.8	1.3	0.6	-0.4	0.3	2.1	0.5	0.5	-0.1	0.2	-0.5	0.7
Overall health rating	1.2	2.5	8.5	-2.9	1.5	2.1	-0.8	0.2	-1.9	2.2	-2.2	-1.6	-0.3	0.6	0.4	-1.4	-0.2	2.0
Chest pain or discomfort	0.3	0.5	1.7	-0.6	1.1	0.1	-0.6	-0.2	-0.8	0.7	-0.5	-1.3	0.1	0.2	0.6	-0.8	1.1	0.3
Had major operations	0.7	0.8	2.6	1.2	-0.8	-1.6	0.3	0.5	1.0	-1.0	1.6	-0.7	0.1	-1.3	-0.6	0.5	0.1	-0.7
Age at last live birth	2.4	3.5	7.6	2.8	-2.1	-2.1	1.8	0.2	2.7	-2.2	2.5	2.7	1.2	0.3	-0.8	1.7	0.5	-1.1
Family relationship satisfaction	0.4	0.5	1.3	0.6	-0.8	-1.0	0.7	0.2	0.9	-0.7	0.9	1.1	0.6	-0.5	-0.1	0.6	0.1	-0.4
Leg pain on walking	0.6	0.7	1.8	-0.8	0.9	0.6	-0.9	-0.4	-1.0	0.7	-0.8	-1.4	-0.1	0.1	1.1	-1.3	0.6	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.7	0.3	0.2	0.9	-0.5	-0.4	-0.3	0.1	-0.3	0.7	0.2	-0.1	0.2	0.1	-0.3	-0.4
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.5	0.3	0.1	0.0	-0.2	-0.4	0.1	-0.2	0.2	-0.7	0.1	-0.5	0.5	0.1	0.1	-0.4
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	2.5	0.2	-0.9	-0.6	1.5	0.8	1.2	-0.9	0.6	1.3	0.2	1.2	0.1	0.9	-0.8	1.6
Medication: Aspirin	0.3	0.5	1.8	-0.2	-0.5	-0.5	0.4	-1.2	0.2	-0.3	0.5	-0.7	-0.4	-0.3	1.4	0.5	0.0	-1.3
Supplements: Vitamin C	0.5	0.6	1.7	1.3	-0.5	-1.0	0.4	-0.9	0.7	-0.7	1.0	-0.7	0.3	-0.1	0.5	0.8	0.4	-1.1
Knee pain experienced in last month	0.8	1.3	4.3	-1.2	0.5	0.3	-0.4	1.8	-0.7	0.6	-0.5	-1.2	1.5	0.4	0.7	-0.9	2.1	1.8
Hypertension (Self-reported)	4.0	11.1	37.9	-0.7	-2.0	-0.8	3.9	-1.1	1.8	-1.2	0.9	1.8	3.8	6.1	5.6	2.4	3.2	6.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	2.9	-0.4	0.2	-0.5	0.2	-0.8	-0.1	0.4	-0.2	-0.6	0.4	0.9	1.7	-0.1	1.3	0.9
Illnesses of father: Heart disease	1.4	1.9	8.7	-1.8	1.6	0.6	-1.7	-1.1	-1.5	1.5	-1.3	-2.9	-0.9	0.0	1.2	-1.2	0.2	-0.5
Illnesses of siblings: Diabetes	0.2	0.3	1.2	0.4	-0.8	-0.5	0.0	-0.2	0.5	-0.0	0.1	-0.3	-0.5	-0.4	-0.9	0.3	-1.1	-0.3
Smoking status: Previous	5.5	8.2	20.1	-3.4	4.0	2.8	-3.4	2.4	-3.7	4.0	-3.7	-1.0	-0.7	-0.9	-0.3	-4.5	1.0	1.8
Forced expiratory volume in 1-second (FEV1), predicted	7.0	14.6	33.3	3.4	-4.5	-4.7	5.8	-1.8	5.0	-4.9	5.4	0.9	2.3	3.0	2.4	5.3	0.5	1.2
Whole body fat-free mass	1.2	6.7	23.6	-0.7	-1.7	-1.3	3.0	0.2	1.1	-1.1	1.9	-1.2	2.7	3.4	4.9	1.7	3.5	4.5
Leg fat-free mass (right)	0.7	3.9	13.3	-3.4	0.8	1.5	0.2	0.8	-1.9	1.8	-0.9	-2.7	0.2	1.8	3.0	-0.9	1.6	3.6
Arm fat percentage (left)	31.9	127.1	275.6	-16.6	13.3	14.8	-12.0	4.1	-16.0	15.2	-15.5	-8.9	-7.3	-3.0	-1.7	-13.4	-2.6	4.1
Average weekly red wine intake	0.6	0.9	5.8	0.4	-0.4	-0.5	1.0	-1.5	0.6	-0.4	1.2	0.1	-0.2	0.9	2.4	0.7	0.4	0.7
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.1	0.9	-0.8	-1.0	0.4	1.0	0.8	-0.7	0.8	1.4	0.2	0.1	-1.2	0.3	-0.0	-0.3
Mood swings	0.5	0.8	2.4	-0.5	1.3	0.9	-0.4	1.2	-0.8	1.0	-1.0	1.6	0.7	-0.3	-0.6	-1.3	0.6	0.6
Loneliness, isolation	2.6	3.6	7.6	-2.0	2.0	2.6	-2.1	1.6	-2.8	1.9	-2.6	-1.9	-1.1	-1.5	-1.0	-2.4	-0.9	-0.5
Long-standing illness, disability or infirmity	2.0	3.0	8.1	-2.8	2.0	1.8	-1.5	-0.1	-2.2	2.2	-2.3	-2.5	-1.5	-0.3	-0.3	-1.8	-0.9	0.3
Ever had bowel cancer screening	1.0	1.2	2.8	1.7	-1.1	-1.5	1.3	-0.5	1.5	-1.2	1.2	1.3	0.3	1.3	0.8	0.8	-0.3	0.5
Diabetes diagnosed by doctor	2.3	3.8	9.8	-3.1	1.7	2.3	-2.0	3.1	-2.3	2.1	-2.5	-0.6	0.2	-0.9	-0.7	-2.3	-0.1	1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.7	4.1	1.7	-1.1	-1.6	0.9	0.6	1.2	-1.7	1.6	-0.6	1.8	0.8	0.1	1.1	2.0	0.9
Friendships satisfaction	1.1	1.3	3.0	1.2	-1.3	-1.0	0.6	-1.0	1.2	-0.9	1.6	0.5	-1.1	-1.0	-0.7	1.4	-1.5	-1.7
Qualifications: nursing, teaching	0.4	0.7	4.5	-0.9	-0.6	-0.4	0.0	-1.2	-0.2	0.1	-0.2	-2.1	-0.6	-0.1	0.5	0.5	-0.1	-1.1
Commuting to job workplace: Walk	0.4	0.5	1.9	0.5	-0.5	-0.5	0.3	0.2	0.7	-0.3	0.4	1.4	-0.8	-0.3	-0.7	0.2	-1.4	-0.6
Eye problems/disorders: Cataract	0.9	1.0	2.2	-0.8	0.9	0.4	-0.2	1.4	-0.9	0.9	-0.8	0.9	0.8	1.0	1.5	-1.3	1.4	1.3
Mouth/teeth dental problems: Mouth ulcers	1.2	2.0	4.4	1.0	-1.1	-1.3	1.3	0.1	1.5	-1.0	1.4	1.0	1.9	1.7	1.1	1.4	2.1	1.9
Medication for cholesterol	1.6	2.5	10.5	0.9	0.7	0.4	-1.2	-0.5	-0.2	0.4	-0.0	0.0	-1.9	-2.8	-2.7	-0.5	-2.0	-3.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	2.6	1.1	-0.4	-1.3	0.7	1.2	0.7	-1.1	1.1	0.4	1.6	0.6	0.5	0.4	1.5	1.2
Back pain experienced in last month	0.2	0.3	0.7	-0.0	-0.4	-0.3	0.7	-0.8	0.5	-0.4	0.7	-0.8	-0.2	-0.3	-0.7	0.8	-0.8	-0.4
Mineral and other dietary supplements	0.8	1.0	2.2	-0.6	0.9	1.5	-0.9	-0.2	-1.0	1.0	-1.0	0.8	-1.1	-1.2	-1.3	-0.4	-1.5	-0.9
Breast cancer (self-reported)	0.7	0.9	2.5	1.1	-1.2	0.2	0.8	1.1	1.0	-0.9	0.8	1.6	1.2	0.2	-0.9	0.7	0.0	0.8
Asthma (self-reported)	0.7	1.4	3.3	-1.8	1.6	1.5	-1.0	0.9	-1.3	1.6	-1.5	0.3	-1.2	-0.6	-0.9	-1.2	-0.9	0.9
Osteoporosis (self-reported)	0.7	0.9	3.2	-1.7	-0.3	-0.0	0.8	-0.8	-0.3	0.2	0.1	-1.8	-0.2	1.5	1.1	0.8	0.3	1.1
Osteoarthritis (self-reported)	3.4	4.4	10.8	-2.6	2.9	2.9	-2.4	-0.4	-2.6	3.3	-2.9	-0.8	-0.6	-0.7	0.2	-2.7	0.6	0.8
Medication: Aspirin	0.5	0.6	2.9	-0.2	-0.7	-0.6	0.6	-1.7	0.4	-0.3	0.5	-0.8	-0.5	-0.1	1.6	0.7	-0.1	-1.1
Medication: Gliclazide	0.2	0.2	1.3	-1.1	-0.2	0.8	0.1	-0.0	-0.2	0.3	-0.2	-0.6	0.1	0.4	-0.2	0.3	-0.4	0.3
Illnesses of father: None of the above (group 1)	0.9	1.2	3.1	-0.9	0.7	0.8	-1.3	1.6	-1.1	0.7	-0.7	-0.0	-0.8	-1.7	-1.8	-1.3	-0.6	-0.7
Smoking status: Current	1.2	1.8	5.6	-1.4	1.3	1.8	-0.9	-1.4	-1.6	1.6	-1.2	-2.4	-1.7	-0.2	-0.4	-0.8	-1.4	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	5.2	0.3	-0.7	-1.4	1.3	-0.6	0.9	-0.6	0.9	0.5	1.3	2.1	2.1	0.9	2.3	2.1
Whole body water mass	1.2	7.0	24.2	-0.7	-1.7	-1.3	3.1	0.2	1.0	-1.1	1.9	-1.2	2.8	3.5	4.9	1.8	3.7	4.7
Leg predicted mass (right)	0.7	3.8	13.1	-3.4	0.7	1.5	0.3	0.7	-1.9	1.7	-0.8	-2.7	0.2	1.8	3.0	-0.8	1.6	3.6
Arm fat mass (left)	19.8	81.4	193.2	-13.9	10.4	11.9	-8.8	3.5	-12.9	12.2	-12.2	-7.7	-5.1	-1.3	-0.0	-10.5	-1.0	5.1
Number of self-reported non-cancer illnesses	0.9	1.6	8.3	-0.7	0.1	0.2	0.9	-1.1	-0.0	0.4	-0.7	-0.5	1.1	2.9	1.8	0.2	1.1	2.6
Average weekly champagne plus white wine intake	0.7	0.9	1.9	1.4	-1.3	-0.4	1.4	-1.3	1.0	-0.7	0.9	1.3	0.3	0.8	-0.3	1.3	0.2	-0.2
Miserableness	2.9	5.0	10.8	-2.6	3.2	3.3	-2.5	1.4	-2.9	3.0	-2.8	0.6	-1.3	-1.1	-1.2	-2.8	-1.0	0.2
Guilty feelings	2.6	4.0	8.6	-2.6	2.5	2.2	-2.1	2.6	-2.6	2.3	-2.8	-0.7	0.3	0.0	-0.1	-2.9	0.8	0.7
Wears glasses or contact lenses	0.4	0.5	2.1	-1.0	0.1	0.3	0.9	-0.1	-0.2	-0.1	-0.2	-0.6	0.5	1.5	0.7	0.3	0.8	1.3
Ever taken oral contraceptive pill	0.6	0.7	2.6	0.7	-0.3	-0.4	0.7	1.1	0.5	-0.8	0.7	0.6	1.6	0.2	0.2	0.4	1.5	1.0
Hearing aid user	6.6	7.5	15.5	-3.0	3.9	3.6	-3.2	1.2	-3.8	3.9	-3.9	-1.1	-0.9	0.3	-0.2	-3.6	0.7	1.5
Mother’s age at death	0.8	1.1	2.4	-0.7	0.8	1.0	-1.2	0.5	-1.2	1.0	-1.0	0.1	-1.5	-1.4	-1.1	-1.1	-1.1	-0.4
Financial situation satisfaction	0.1	0.2	0.7	0.3	0.5	0.2	-0.2	0.4	-0.1	0.3	-0.1	0.6	0.7	0.0	0.2	-0.3	0.8	0.4
Tinnitus: Yes, now most or all of the time	1.1	1.3	3.6	-1.0	1.4	0.8	-1.0	-0.0	-1.3	1.4	-1.3	-0.1	-0.0	0.6	1.9	-1.5	1.5	0.9
Commuting to job workplace: Public transport	0.6	0.7	2.2	-0.5	0.9	0.4	-1.0	1.0	-0.9	0.9	-0.9	0.8	-0.1	-0.4	-0.4	-1.5	1.0	0.1
Eye problems/disorders: Glaucoma	0.1	0.1	0.5	-0.2	0.3	0.1	-0.4	-0.3	-0.2	0.4	-0.5	-0.1	-0.1	0.3	-0.1	-0.3	0.0	0.7
Medication: Blood pressure	3.6	6.8	23.2	-0.5	-2.0	-1.0	3.2	-0.2	1.5	-1.2	0.8	1.5	3.0	4.8	4.0	1.9	2.5	4.5
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.7	-1.0	0.3	0.5	0.1	-1.4	-0.5	0.7	-0.7	-1.6	-0.0	1.3	1.6	0.4	0.9	0.6
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.3	1.5	-1.0	-1.5	0.9	-0.3	1.3	-1.1	1.2	0.5	0.8	0.8	1.3	0.6	1.1	0.3
High cholesterol (Self-reported)	0.7	1.3	4.6	-1.3	1.0	0.1	-0.5	-0.0	-0.7	0.9	-1.1	-1.2	0.7	1.0	1.9	-0.9	1.5	2.1
Medication: Bendroflumethiazide	3.1	4.7	22.7	-2.4	0.2	1.0	0.9	1.1	-0.9	0.8	-1.5	0.4	2.0	3.5	3.6	-0.7	2.4	4.8
Medication: Paracetamol	1.4	2.2	6.7	-1.7	0.8	0.7	0.1	-0.8	-1.2	1.4	-1.4	-2.0	1.1	2.2	1.8	-0.9	2.6	1.6
Medication: Lisinopril	2.4	3.1	12.0	-0.4	-0.9	-1.5	1.6	0.1	1.2	-0.8	0.8	1.1	2.1	2.3	3.5	1.0	2.3	2.8
Medication: Atorvastatin	0.5	0.6	2.5	0.9	-0.2	-1.5	-0.1	-0.1	0.4	-0.6	0.4	-1.2	0.7	0.2	0.8	-0.1	1.6	-0.6
Illnesses of father: High blood pressure	4.6	5.6	17.6	0.9	-2.0	-1.2	3.4	-1.8	1.9	-1.6	1.3	-0.3	2.3	4.2	3.2	2.8	2.1	3.2
Alcohol drinker status: Never	1.5	1.8	9.6	-0.2	0.6	0.7	-1.5	0.6	-0.5	0.3	-0.4	-0.1	-1.0	-3.1	-1.5	-0.8	-1.7	-2.6
Ever smoked	3.0	5.3	10.3	-3.0	3.2	2.7	-2.2	1.4	-3.1	3.2	-3.0	-2.0	-0.4	-0.2	-0.4	-3.2	0.8	1.8
Basal metabolic rate	1.0	5.3	23.2	-3.0	0.1	0.8	1.4	0.6	-1.1	1.0	-0.2	-2.3	1.5	2.9	4.3	-0.0	2.8	4.8
Leg fat percentage (left)	26.2	94.7	196.0	-14.0	11.9	12.5	-10.6	2.8	-13.5	13.3	-13.4	-7.3	-6.8	-3.0	-2.2	-11.6	-2.7	3.4
Arm fat-free mass (left)	1.2	5.9	23.0	-1.4	-1.0	-0.8	2.4	0.8	0.4	-0.5	1.1	-1.6	2.7	3.1	4.4	1.1	3.7	4.8
Number of operations (self-reported)	1.2	1.8	6.5	-1.0	0.5	-0.2	-0.2	-0.9	-0.5	0.9	-0.3	-2.2	0.7	1.4	2.5	-0.6	2.1	2.2
Average weekly beer plus cider intake	0.3	0.5	1.7	-0.7	0.5	1.0	-0.1	0.6	-0.8	0.5	-0.7	-0.7	-0.1	0.4	-0.7	-0.6	-0.4	1.3
Irritability	1.6	2.7	5.9	-2.2	2.2	2.2	-1.4	1.2	-2.2	2.3	-2.4	-0.1	-0.7	-0.4	-0.4	-2.3	-0.4	0.7
Risk taking	0.2	0.4	1.7	1.3	-0.1	-0.9	-0.3	0.6	0.2	-0.4	0.7	0.2	0.4	-0.7	0.1	-0.4	0.7	-0.7
Ever had prostate specific antigen (PSA) test	1.5	1.7	6.0	2.4	-0.7	-1.7	0.4	-1.0	1.7	-1.5	1.5	1.0	0.0	-0.7	-0.3	0.9	-0.1	-2.2
Fractured/broken bones in last 5 years	0.8	1.0	3.7	-1.6	1.1	1.1	-0.0	-0.7	-1.0	1.2	-1.0	-0.9	-0.6	0.6	1.9	-0.4	0.1	0.9
Age started oral contraceptive pill	0.4	0.5	2.1	-0.3	1.1	0.1	-1.2	1.0	-0.7	0.6	-0.8	0.5	0.1	-0.2	0.4	-1.5	0.6	0.2
Diastolic blood pressure, automated reading	2.8	8.7	18.1	1.1	-2.5	-2.1	4.1	-0.3	2.7	-2.3	2.5	2.3	3.8	4.2	2.6	3.2	3.3	4.3
Ever depressed for a whole week	1.2	1.5	4.3	-0.4	1.4	0.9	-1.3	1.2	-0.8	1.1	-0.9	1.4	-0.8	-1.2	-1.9	-2.1	-1.0	-0.7
Unable to work because of sickness or disability	1.9	2.4	8.2	-2.8	1.2	1.4	-1.1	0.1	-2.0	1.8	-1.9	-2.9	-0.5	0.7	0.8	-1.1	0.3	1.5
Commuting to job workplace: Cycle	0.5	0.6	1.4	-0.8	0.7	0.6	-0.7	1.2	-1.0	1.0	-1.2	-0.3	0.6	0.0	-0.2	-0.7	0.8	0.7
Myopia	3.6	5.2	12.5	2.6	-3.2	-1.9	3.1	-0.6	3.0	-3.1	3.4	1.2	1.1	1.1	-0.8	3.5	-0.6	-0.6
Vascular/heart problems diagnosed by doctor	2.4	6.6	28.6	1.3	0.9	-0.0	-2.6	1.0	-0.7	0.1	0.0	-0.8	-2.5	-4.8	-4.7	-1.2	-2.3	-5.3
Cholesterol lowering medication	0.8	1.2	6.1	-1.2	-0.3	-0.3	0.9	0.1	-0.1	0.0	-0.1	-0.6	0.9	1.9	2.0	0.2	1.0	2.5
Medication: Omeprazole (e.g. Zanprol)	3.6	4.4	17.0	0.3	-0.7	-1.6	1.4	-0.3	1.2	-0.7	0.4	1.6	2.8	3.3	4.1	0.5	3.3	3.1
Pain experienced in last month	0.2	0.3	1.5	0.7	0.2	-0.4	-0.1	-0.9	0.3	-0.1	-0.1	0.7	0.3	1.2	1.0	0.1	0.7	0.0
Supplements: Calcium	1.0	1.1	4.7	0.8	-0.7	-2.2	1.2	1.0	1.3	-1.2	1.0	0.2	1.1	0.3	-0.8	0.8	1.0	0.3
Basal cell carcinoma (self-reported)	0.4	0.5	1.2	1.0	-0.9	-1.1	0.5	-0.9	0.9	-0.7	0.8	0.1	-0.1	0.4	0.1	0.8	0.2	-0.6
Heart attack/myocardial infarction (self-reported)	0.9	1.2	5.3	0.6	-0.1	-0.3	-0.7	-1.9	-0.1	-0.2	0.6	-2.3	-1.2	-1.1	-0.2	0.0	-0.9	-2.0
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	5.5	-0.2	0.3	0.6	-0.9	-1.4	-0.4	0.6	-0.3	-0.0	-2.3	-1.8	-1.1	-0.6	-2.4	-2.0
Heart disease (siblings)	4.0	4.9	10.6	-2.6	3.2	1.7	-3.3	0.4	-2.5	2.9	-2.5	-1.6	-2.3	-2.0	-0.6	-2.9	-0.9	-0.4
Alcohol drinker status: Previous	0.6	0.6	1.8	-0.4	1.3	0.2	-0.7	0.9	-0.6	0.8	-1.0	-0.1	0.8	0.3	0.4	-1.1	1.4	0.8
Pack years of smoking	3.1	4.6	8.8	-3.0	2.3	2.7	-2.3	1.3	-2.9	2.6	-2.6	-2.8	-1.1	-0.8	-1.1	-2.5	-0.9	0.7
Impedance of whole body	2.9	14.9	28.8	5.0	-4.5	-4.0	5.0	-2.7	5.4	-4.9	5.0	4.0	2.6	2.3	0.9	4.7	0.2	-1.2
Leg fat mass (left)	19.0	74.0	166.4	-12.9	10.4	11.1	-8.8	2.7	-12.1	11.8	-11.7	-7.0	-5.5	-2.0	-0.5	-10.1	-1.5	4.1
Arm predicted mass (left)	1.3	6.6	26.0	-1.3	-1.0	-0.8	2.6	0.5	0.5	-0.4	1.2	-1.4	2.9	3.4	4.7	1.2	3.9	5.1