310 significantly associated models · 46 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 71163715 | 73435171 | 1 | 1 | 1.3e-13 | 1.2e-14 | 1.8e-03 | 84 | NEGR1 |
2 | 2 | 24348096 | 25837917 | 1 | 1 | 1.3e-07 | 1.8e-07 | 3.6e-01 | 97 | ADCY3 |
3 | 3 | 140514022 | 142017527 | 1 | 1 | 3.0e-07 | 1.1e-06 | 6.3e-02 | 85 | RASA2 |
4 | 3 | 185520342 | 186072370 | 1 | 1 | 2.2e-12 | 1.3e-12 | 2.2e-02 | 90 | ETV5 |
5 | 11 | 46570859 | 48485877 | 11 | 1 | 2.5e-11 | 4.8e-11 | 1.0e+00 | 100 | C1QTNF4 |
6 | 12 | 49569311 | 50991370 | 1 | 1 | 2.2e-08 | 4.0e-11 | 1.3e-04 | 67 | FAIM2 |
7 | 13 | 27315078 | 28717392 | 1 | 1 | 1.3e-07 | 3.0e-07 | 5.6e-02 | 86 | MTIF3 |
8 | 15 | 67138238 | 68789191 | 1 | 1 | 2.6e-11 | 1.2e-10 | 1.3e-01 | 94 | MAP2K5 |
9 | 16 | 19022448 | 20596558 | 5 | 1 | 9.8e-11 | 4.6e-11 | 1.0e+00 | 100 | GPRC5B |
10 | 16 | 27655848 | 29595483 | 19 | 1 | 3.1e-13 | 1.7e-10 | 2.4e-01 | 97 | EIF3CL |
11 | 16 | 52828325 | 54846383 | 2 | 2 | 1.0e-17 | 3.1e-62 | 7.9e-37 | 42 | AKTIP FTO |
12 | 18 | 57349900 | 58729694 | 1 | 1 | 2.6e-07 | 2.1e-22 | 1.1e-16 | 28 | MC4R |
13 | 19 | 34044119 | 34553925 | 1 | 1 | 2.3e-07 | 2.4e-09 | 1.0e+00 | 100 | KCTD15 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Vagina | 5 | 0.814 | 1.7 |
GTEx | Brain Cerebellar Hemisphere | 1 | 0.069 | 1.6 |
GTEx | Brain Cerebellum | 1 | 0.052 | 1.6 |
GTEx | Brain Cortex | 4 | 0.399 | 1.6 |
GTEx | Heart Left Ventricle | 6 | 0.406 | 1.6 |
GTEx | Liver | 3 | 0.430 | 1.6 |
GTEx | Ovary | 5 | 0.567 | 1.6 |
GTEx | Spleen | 5 | 0.363 | 1.6 |
GTEx | Stomach | 5 | 0.353 | 1.6 |
GTEx | Whole Blood | 7 | 0.365 | 1.6 |
GTEx | Adipose Subcutaneous | 11 | 0.325 | 1.5 |
GTEx | Adipose Visceral Omentum | 4 | 0.203 | 1.5 |
GTEx | Artery Aorta | 10 | 0.348 | 1.5 |
GTEx | Artery Coronary | 2 | 0.173 | 1.5 |
GTEx | Artery Tibial | 10 | 0.275 | 1.5 |
GTEx | Brain Caudate basal ganglia | 2 | 0.224 | 1.5 |
GTEx | Brain Frontal Cortex BA9 | 1 | 0.112 | 1.5 |
GTEx | Brain Hypothalamus | 1 | 0.175 | 1.5 |
GTEx | Brain Nucleus accumbens basal ganglia | 2 | 0.237 | 1.5 |
GTEx | Brain Putamen basal ganglia | 1 | 0.165 | 1.5 |
GTEx | Breast Mammary Tissue | 8 | 0.419 | 1.5 |
GTEx | Cells EBV-transformed lymphocytes | 1 | 0.073 | 1.5 |
GTEx | Cells Transformed fibroblasts | 8 | 0.196 | 1.5 |
GTEx | Colon Transverse | 6 | 0.302 | 1.5 |
GTEx | Esophagus Gastroesophageal Junction | 4 | 0.286 | 1.5 |
GTEx | Esophagus Mucosa | 5 | 0.155 | 1.5 |
GTEx | Esophagus Muscularis | 10 | 0.319 | 1.5 |
GTEx | Heart Atrial Appendage | 4 | 0.261 | 1.5 |
GTEx | Lung | 6 | 0.216 | 1.5 |
GTEx | Muscle Skeletal | 6 | 0.214 | 1.5 |
GTEx | Nerve Tibial | 9 | 0.215 | 1.5 |
GTEx | Pancreas | 3 | 0.189 | 1.5 |
GTEx | Pituitary | 2 | 0.183 | 1.5 |
GTEx | Skin Not Sun Exposed Suprapubic | 8 | 0.334 | 1.5 |
GTEx | Skin Sun Exposed Lower leg | 9 | 0.255 | 1.5 |
GTEx | Small Intestine Terminal Ileum | 1 | 0.222 | 1.5 |
GTEx | Testis | 10 | 0.327 | 1.5 |
ROSMAP | Brain Pre-frontal Cortex | 6 | 0.141 | 1.5 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 2 | 0.192 | 1.5 |
GTEx | Breast Mammary Tissue (Male) | 4 | 0.345 | 1.4 |
GTEx | Breast Mammary Tissue (Female) | 4 | 0.254 | 1.4 |
GTEx | Colon Sigmoid | 4 | 0.281 | 1.4 |
GTEx | Prostate | 2 | 0.248 | 1.4 |
GTEx | Thyroid | 3 | 0.078 | 1.4 |
GTEx | Uterus | 1 | 0.181 | 1.4 |
METSIM | Adipose | 8 | 0.177 | 1.4 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 4 | 0.259 | 1.4 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 4 | 0.208 | 1.4 |
The Cancer Genome Atlas | Esophageal Carcinoma | 1 | 0.154 | 1.4 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 1 | 0.104 | 1.4 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 6 | 0.234 | 1.4 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 5 | 0.259 | 1.4 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 5 | 0.123 | 1.4 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 4 | 0.384 | 1.4 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 4 | 0.170 | 1.4 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 3 | 0.201 | 1.4 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 3 | 0.189 | 1.4 |
GTEx | Adrenal Gland | 2 | 0.141 | 1.3 |
GTEx | Brain Hippocampus | 1 | 0.197 | 1.3 |
NTR | Blood | 2 | 0.084 | 1.3 |
YFS | Blood | 3 | 0.066 | 1.3 |
CommonMind | Brain Pre-frontal Cortex | 8 | 0.152 | 1.3 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 6 | 0.145 | 1.3 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 6 | 0.155 | 1.3 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 5 | 0.181 | 1.3 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 2 | 0.127 | 1.3 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 2 | 0.160 | 1.3 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 4 | 0.092 | 1.3 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 1 | 0.101 | 1.3 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 2 | 0.405 | 1.3 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Thyroid Carcinoma | 5 | 0.102 | 1.3 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 1 | 0.208 | 1.3 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 0 | 0.000 | 1.2 |