Best TWAS P=1.19e-07 · Best GWAS P=3.89e-19 conditioned to 1.05e-19
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | ZDHHC11 | 0.08 | 0.02 | enet | 22 | 0.06 | 2.2e-05 | -2.5 | -5.3 | 1.2e-07 | -0.05 | 0.08 | 0.04 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | EXOC3 | 0.40 | 0.32 | enet | 19 | 0.36 | 5.3e-49 | 4.6 | -5.3 | 1.4e-07 | 0.07 | 0.12 | 0.86 | TRUE |