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chr5:44,048,891-45,516,364

Best TWAS P=4.79e-58 · Best GWAS P=4.79e-58 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RP11-53O19.3	0.06	0.09	lasso	1	0.08	3.0e-07	-14	14	3.9e-43	-0.62	0.55	0.44	FALSE
2	GTEx	Artery Aorta	RP11-53O19.3	0.08	0.12	enet	11	0.08	6.0e-05	-12	14	5.4e-45	-0.68	0.94	0.05	FALSE
3	GTEx	Artery Tibial	RP11-53O19.3	0.03	0.02	enet	10	0.03	1.3e-03	-12	13	3.7e-38	-0.65	0.50	0.26	FALSE
4	GTEx	Breast Mammary Tissue	RP11-53O19.1	0.06	0.06	lasso	1	0.03	1.0e-02	-16	-16	4.8e-58	1.00	0.01	0.93	TRUE
5	GTEx	Heart Atrial Appendage	RP11-53O19.1	0.17	0.17	lasso	5	0.17	3.8e-08	-14	13	1.1e-40	-0.59	0.90	0.10	FALSE
6	GTEx	Heart Left Ventricle	RP11-53O19.1	0.13	0.22	lasso	2	0.21	2.4e-11	-14	14	1.7e-43	-0.62	1.00	0.00	FALSE
7	GTEx	Lung	RP11-53O19.3	0.04	0.04	enet	8	0.05	7.8e-05	-14	12	2.2e-35	-0.44	0.55	0.06	FALSE
8	GTEx	Nerve Tibial	RP11-53O19.3	0.08	0.14	enet	15	0.13	1.3e-09	-14	13	4.0e-37	-0.63	1.00	0.00	TRUE
9	GTEx	Skin Not Sun Exposed Suprapubic	RP11-53O19.3	0.05	0.07	lasso	2	0.04	3.6e-03	-14	14	1.0e-46	-0.57	0.09	0.63	TRUE
10	GTEx	Spleen	RP11-53O19.3	0.26	0.13	enet	12	0.06	1.2e-02	-14	16	7.9e-58	-0.70	0.22	0.18	TRUE
11	GTEx	Stomach	RP11-53O19.3	0.06	0.10	lasso	1	0.09	3.0e-05	-14	14	1.6e-41	-0.62	0.63	0.08	FALSE
12	GTEx	Testis	RP11-53O19.3	0.07	0.08	lasso	2	0.07	3.2e-04	-12	12	2.8e-34	-0.65	0.30	0.15	FALSE
13	GTEx	Thyroid	RP11-53O19.3	0.12	0.14	enet	14	0.14	1.3e-10	-12	13	1.5e-37	-0.64	1.00	0.00	FALSE
14	METSIM	Adipose	RP11-53O19.3	0.05	0.06	lasso	6	0.05	3.9e-08	-12	15	7.6e-50	-0.79	0.40	0.60	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	MRPS30	0.04	0.04	enet	4	0.04	1.5e-09	-14	-14	2.0e-43	0.58	0.00	1.00	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	MRPS30	0.02	0.01	blup	29	0.01	1.6e-02	-12	-12	6.3e-33	0.65	0.04	0.82	TRUE