Best TWAS P=1.3e-09 · Best GWAS P=1.55e-09 conditioned to 0.15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PPM1K | 0.04 | 0.05 | lasso | 3 | 0.04 | 5.4e-09 | -6.0 | -6.0 | 2.6e-09 | 0.99 | 0 | 1 | FALSE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PPM1K | 0.13 | 0.11 | enet | 6 | 0.14 | 8.8e-15 | -5.7 | -6.1 | 1.3e-09 | 0.88 | 0 | 1 | TRUE |