[Hub]/) : Traits : Breast Cancer : ← →

chr5:55,509,554-56,923,759

Best TWAS P=7.53e-67 · Best GWAS P=8.81e-98 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	SETD9	0.15	0.14	lasso	10	0.16	3.0e-13	-7.576	5.3	1.1e-07	-0.04	1.00	0.00	FALSE
2	GTEx	Brain Putamen basal ganglia	SETD9	0.23	0.15	lasso	3	0.14	2.9e-04	-9.515	8.9	5.7e-19	-0.19	0.22	0.04	FALSE
3	GTEx	Breast Mammary Tissue	CTD-2310F14.1	0.14	-0.01	enet	23	0.01	6.7e-02	6.303	-7.2	6.6e-13	0.27	0.07	0.31	TRUE
4	GTEx	Breast Mammary Tissue (Female)	SETD9	0.21	0.12	lasso	11	0.16	1.4e-05	-14.260	11.2	4.9e-29	-0.33	0.57	0.04	TRUE
5	GTEx	Breast Mammary Tissue (Female)	CTD-2310F14.1	0.21	0.01	lasso	6	0.02	9.4e-02	4.875	-6.0	2.2e-09	0.26	0.05	0.55	TRUE
6	GTEx	Cells Transformed fibroblasts	SETD9	0.31	0.42	lasso	6	0.47	5.7e-39	0.440	5.7	1.3e-08	-0.06	1.00	0.00	FALSE
7	GTEx	Spleen	CTD-2310F14.1	0.38	0.00	enet	21	0.01	2.0e-01	-16.491	-17.3	7.5e-67	0.60	0.04	0.50	TRUE
8	GTEx	Stomach	SETD9	0.35	0.31	lasso	8	0.38	1.9e-19	0.440	5.7	1.6e-08	-0.07	1.00	0.00	TRUE
9	GTEx	Testis	SETD9	0.18	0.05	lasso	6	0.11	1.9e-05	-7.301	8.0	1.3e-15	-0.12	0.73	0.01	FALSE
10	GTEx	Testis	CTD-2310F14.1	0.35	0.14	lasso	8	0.15	2.9e-07	-0.064	-8.1	7.8e-16	0.12	0.94	0.00	FALSE
11	METSIM	Adipose	SETD9	0.10	0.14	lasso	17	0.16	9.6e-23	-7.310	5.4	5.5e-08	-0.04	1.00	0.00	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	C5orf35	0.29	0.42	lasso	8	0.46	3.0e-107	0.440	5.2	1.8e-07	-0.07	1.00	0.00	FALSE
13	The Cancer Genome Atlas	Esophageal Carcinoma	C5orf35	0.19	0.20	lasso	4	0.18	1.9e-06	-7.301	6.4	1.2e-10	-0.07	0.81	0.01	FALSE
14	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C5orf35	0.27	0.30	lasso	6	0.36	1.4e-21	0.440	5.6	2.5e-08	-0.07	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	MIER3	0.05	0.00	blup	81	0.01	6.2e-02	-0.117	-8.0	1.0e-15	0.31	0.03	0.12	TRUE
16	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C5orf35	0.23	0.39	lasso	11	0.37	1.9e-18	-7.301	7.6	2.4e-14	-0.12	1.00	0.00	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	C5orf35	0.42	0.45	enet	17	0.50	3.2e-67	0.440	5.2	2.6e-07	-0.07	1.00	0.00	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	MAP3K1	0.02	0.01	blup	83	0.01	9.1e-03	-13.795	-14.2	8.8e-46	0.64	0.06	0.44	TRUE
19	The Cancer Genome Atlas	Skin Cutaneous Melanoma	C5orf35	0.23	0.08	blup	58	0.17	2.5e-05	-15.283	10.2	1.3e-24	-0.27	0.52	0.05	FALSE
20	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MIER3	0.17	0.12	lasso	3	0.07	1.6e-03	-10.660	-11.6	2.5e-31	0.62	0.02	0.54	TRUE
21	The Cancer Genome Atlas	Thyroid Carcinoma	MAP3K1	0.04	0.03	lasso	2	0.03	4.4e-04	-12.627	-13.4	5.6e-41	0.62	0.09	0.63	TRUE
22	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	C5orf35	0.38	0.05	blup	58	0.06	7.0e-03	-0.117	6.5	7.9e-11	-0.09	0.13	0.04	TRUE