Best TWAS P=2.06e-10 · Best GWAS P=6.43e-13 conditioned to 2.47e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | RANBP9 | 0.13 | 0.14 | lasso | 2 | 0.13 | 1.9e-07 | 6.3 | -6.4 | 2.1e-10 | 0.60 | 0.76 | 0.24 | TRUE |
| 2 | GTEx | Artery Tibial | RANBP9 | 0.12 | 0.04 | enet | 15 | 0.05 | 1.5e-04 | 6.1 | -5.7 | 1.4e-08 | 0.53 | 0.66 | 0.13 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | SIRT5 | 0.16 | 0.07 | blup | 60 | 0.06 | 9.2e-03 | 4.1 | -5.8 | 8.8e-09 | 0.46 | 0.03 | 0.55 | FALSE |