Best TWAS P=1.05e-29 · Best GWAS P=4.81e-54 conditioned to 5.55e-25
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | C6orf97 | 0.05 | 0.00 | blup | 133 | 0.03 | 1.3e-03 | -1.8 | -9.1 | 9.6e-20 | 0.51 | 0.05 | 0.15 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | C6orf97 | 0.01 | 0.01 | enet | 7 | 0.01 | 5.3e-03 | -2.5 | -5.7 | 1.3e-08 | 0.42 | 0.08 | 0.49 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | C6orf97 | 0.08 | 0.02 | blup | 133 | 0.07 | 6.2e-08 | -5.0 | -11.3 | 1.0e-29 | 0.46 | 0.72 | 0.12 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C6orf97 | 0.06 | 0.05 | lasso | 3 | 0.08 | 6.9e-09 | -4.5 | -10.0 | 9.6e-24 | 0.64 | 0.61 | 0.33 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C6orf97 | 0.08 | 0.04 | blup | 133 | 0.09 | 1.2e-10 | -1.8 | -8.8 | 1.4e-18 | 0.52 | 0.84 | 0.16 | FALSE |
| 6 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | C6orf97 | 0.23 | 0.10 | lasso | 11 | 0.11 | 1.8e-05 | -1.8 | -5.7 | 1.3e-08 | 0.28 | 0.44 | 0.02 | TRUE |