TWAS hub - C6orf97

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0520	0.0250	2.8e-03	-0.002	0.030	-0.001	NA	-0.002	5.5e-01	1.3e-03	3.9e-01	NA	6.0e-01
2	TCGA	Breast Invasive Carcinoma	0.0146	0.0075	5.5e-03	0.007	0.007	0.009	NA	0.006	1.3e-02	8.9e-03	5.3e-03	NA	1.6e-02
3	TCGA	Head and Neck Squamous Cell Carcinoma	0.0783	0.0265	7.5e-07	0.025	0.066	0.042	NA	0.030	7.8e-04	6.2e-08	1.5e-05	NA	2.6e-04
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0559	0.0230	7.5e-05	0.049	0.043	0.075	NA	0.076	3.1e-06	1.2e-05	7.4e-09	NA	6.9e-09
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1780	0.0720	1.0e-03	0.061	0.020	0.029	NA	0.047	2.3e-04	2.5e-02	8.6e-03	NA	1.1e-03
6	TCGA	Brain Lower Grade Glioma	0.0798	0.0247	6.1e-09	0.040	0.092	0.067	NA	0.066	2.3e-05	1.2e-10	4.4e-08	NA	5.6e-08
7	TCGA	Lung Adenocarcinoma	0.0659	0.0274	8.7e-05	0.034	0.043	0.048	NA	0.050	6.2e-05	8.8e-06	2.5e-06	NA	1.7e-06
8	TCGA	Ovarian Serous Cystadenocarcinoma	0.1380	0.0570	3.9e-04	0.014	0.079	0.070	NA	0.012	3.4e-02	5.2e-06	1.8e-05	NA	4.7e-02
9	TCGA	Pancreatic Adenocarcinoma	0.2260	0.0810	2.0e-05	0.101	0.099	0.104	NA	0.113	5.1e-05	5.9e-05	4.1e-05	NA	1.8e-05
10	TCGA	Prostate Adenocarcinoma	0.0981	0.0347	8.2e-07	0.055	0.065	0.057	NA	0.041	2.0e-06	2.6e-07	1.4e-06	NA	3.9e-05
11	TCGA	Stomach Adenocarcinoma	0.1260	0.0490	3.7e-04	0.022	0.046	0.033	NA	0.022	9.2e-03	2.8e-04	1.9e-03	NA	9.6e-03
12	TCGA	Thyroid Carcinoma	0.0820	0.0320	9.6e-05	0.018	0.036	0.048	NA	0.056	6.7e-03	1.9e-04	1.7e-05	NA	3.4e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Heel T-Score	136.6	1086.2	2088.5	-42.0	-38.6	-32.2	-29.4	-16.8	-36.1	-30.0	-28.8	-45.7	-25.9	-25.6	-33.9
Heel bone mineral density (BMD) T-score, automated (left)	95.1	215.6	420.2	-18.4	-17.3	-14.1	-12.8	-7.4	-15.7	-13.3	-12.8	-20.5	-11.6	-12.1	-15.6
Heel bone mineral density (BMD) T-score, automated (right)	83.9	192.3	372.5	-17.5	-16.7	-13.2	-12.4	-6.8	-14.8	-12.2	-12.2	-19.3	-10.6	-11.4	-14.7
Breast Cancer	17.3	41.8	127.7	-9.1	-5.7	-11.3	-10.0	2.6	-8.8	-3.0	3.0	-5.7	-3.6	-2.2	-2.5
Fractured/broken bones in last 5 years	12.1	15.6	26.6	5.2	3.8	5.1	3.8	2.2	4.0	4.2	1.6	4.7	2.8	3.9	4.6
Commuting to job workplace: Car/motor vehicle	6.8	7.7	16.0	3.4	3.2	2.8	2.4	1.3	3.3	2.3	2.2	4.0	2.1	1.9	3.2
Number of live births	5.9	8.3	25.0	3.5	5.0	1.3	4.2	0.7	2.1	1.3	3.0	3.7	1.1	2.5	2.6
Breast cancer (self-reported)	4.6	5.5	18.9	2.1	1.4	4.3	4.3	-2.8	3.1	-0.2	-0.8	1.4	0.3	-0.3	1.1
Osteoporosis (self-reported)	4.3	5.4	9.7	3.0	2.8	2.5	2.5	0.4	2.4	1.3	1.9	3.1	1.6	2.0	2.8
Illnesses of father: Heart disease	4.1	5.7	10.7	1.8	2.3	0.8	0.4	2.5	2.0	2.5	3.3	2.6	3.2	2.6	3.0
Commuting to job workplace: Walk	3.8	4.1	6.4	-2.2	-2.4	-1.4	-1.6	-1.9	-2.1	-1.9	-1.9	-2.5	-1.2	-2.2	-2.5
LDL Cholesterol	3.4	5.4	9.8	3.0	2.5	2.3	2.5	1.9	2.2	2.0	1.6	2.3	1.6	2.2	3.1
Illnesses of father: None of the above (group 1)	3.4	4.2	8.2	-2.9	-2.1	-1.6	-0.6	-2.3	-1.6	-2.5	-1.6	-2.6	-2.5	-1.0	-2.3
High blood pressure	3.3	9.1	22.9	4.8	3.5	2.3	1.8	3.0	3.2	3.2	1.8	4.3	1.9	1.6	3.0
Hypertension (Self-reported)	3.2	8.8	22.4	4.7	3.6	2.2	2.0	2.9	3.1	3.1	2.0	4.0	1.8	1.7	2.8
Qualifications: CSEs or equivalent	2.9	3.8	7.5	1.5	1.5	1.5	0.7	2.1	1.9	2.3	2.5	1.9	2.7	1.4	2.4
Comparative body size at age 10	2.8	7.7	13.8	2.5	3.5	2.8	3.7	0.1	3.0	1.5	2.2	3.1	2.1	3.3	3.2
Osteoarthritis (self-reported)	2.8	3.6	11.1	2.2	2.3	2.0	3.3	0.7	2.1	1.4	1.0	2.0	0.9	2.0	1.2
Tinnitus: Yes, but not now, but have in the past	2.5	2.7	5.6	1.7	1.7	2.4	1.6	-0.0	2.1	0.9	0.6	2.3	1.2	1.7	1.8
Hair/balding pattern: Pattern 3	2.5	3.8	7.1	-1.6	-1.6	-0.2	0.1	-2.5	-1.2	-2.6	-2.5	-2.2	-1.9	-2.7	-1.9
Vascular/heart problems diagnosed by doctor	2.5	6.8	18.8	-4.3	-3.0	-1.7	-1.5	-2.9	-2.5	-3.1	-1.5	-3.7	-1.3	-1.5	-2.4
Cardiovascular Disease	2.4	7.8	14.0	3.7	3.3	1.2	1.3	3.3	2.0	3.3	3.2	3.7	1.7	2.2	2.9
Schizophrenia vs Biploar Disorder	2.3	3.0	5.8	-1.9	-2.4	-1.9	-1.8	-0.0	-1.9	-1.2	-1.5	-1.5	-2.0	-1.8	-1.8
Tinnitus: Yes, now most or all of the time	2.3	2.7	6.1	-1.8	-2.5	-1.7	-2.3	0.2	-1.8	-0.7	-1.4	-1.9	-1.1	-1.6	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.1	2.4	5.4	-1.7	-1.9	-1.0	-1.8	-1.4	-1.6	-1.4	-1.2	-1.1	-0.8	-2.3	-1.8
Number of full brothers	2.0	2.5	5.5	1.6	1.8	2.0	0.9	0.9	1.5	1.3	1.3	1.6	2.4	0.5	1.9
Ever used hormone-replacement therapy (HRT)	1.9	2.5	4.6	-2.1	-2.0	-1.3	-1.7	-1.2	-1.3	-1.6	-0.8	-1.9	-1.1	-2.0	-1.2
Medication: Metformin	1.9	2.6	5.2	1.7	1.5	1.7	1.6	0.5	2.0	1.1	0.8	2.0	1.8	2.3	1.4
Knee pain experienced in last month	1.9	2.9	5.3	2.1	2.3	0.7	1.9	2.1	1.3	1.8	1.7	1.6	1.6	1.5	1.1
Number of full sisters	1.8	2.2	7.2	2.0	1.7	1.7	1.0	0.3	1.9	1.0	0.7	2.7	1.2	0.2	1.2
Handedness (chirality/laterality): Left-handed	1.8	2.2	4.4	-1.7	-1.6	-2.1	-2.1	0.3	-1.9	-0.6	0.5	-1.8	-1.1	-1.1	-1.5
Average weekly spirits intake	1.7	2.2	5.2	-0.9	-2.1	-0.7	-0.9	0.2	-1.5	-0.1	-2.1	-2.3	-1.3	-1.7	-1.5
Chronic bronchitis/emphysema (father)	1.7	2.0	5.8	2.4	0.9	1.8	0.6	1.0	1.6	1.7	0.2	1.8	1.5	0.5	1.1
Number of self-reported non-cancer illnesses	1.7	3.0	4.6	1.9	1.5	1.4	1.5	1.9	1.8	2.1	1.4	2.0	1.9	1.2	1.8
Mother’s age at death	1.7	2.1	6.9	-2.6	-1.6	-1.5	-1.5	-1.7	-1.7	-1.6	-0.7	-1.2	-0.6	-0.2	-1.0
Type 2 Diabetes (T2D) (2012)	1.6	1.8	3.9	-1.5	-2.0	-1.8	-1.2	0.9	-1.6	0.2	0.0	-1.8	-0.8	-0.8	-1.7
Supplements: Zinc	1.6	1.8	9.3	0.9	1.6	1.7	3.1	-1.5	1.7	-0.5	-0.2	0.4	0.6	-0.1	0.1
Average weekly fortified wine intake	1.6	1.9	4.1	-1.9	-2.0	-0.7	-1.2	-1.1	-1.3	-0.9	-1.8	-1.4	-0.8	-1.0	-1.6
Fed-up feelings	1.6	2.9	5.1	1.5	1.9	2.2	2.0	-0.1	1.9	0.8	1.7	2.3	1.5	0.8	2.2
Breastfed as a baby	1.6	2.0	9.4	0.5	1.6	-0.2	0.5	1.1	0.9	0.7	3.1	1.3	1.4	1.8	1.6
Overall health rating	1.6	3.4	7.5	1.8	2.1	1.3	1.1	1.1	2.0	1.4	2.7	2.6	1.5	0.7	2.3
Ever depressed for a whole week	1.6	2.0	7.5	-0.4	-0.5	-2.7	-0.7	0.5	-1.9	-0.4	0.4	-0.9	-2.3	-1.1	-2.0
Medication: Atenolol	1.5	1.9	5.1	2.3	1.7	1.3	0.8	0.9	1.6	1.2	1.4	1.9	0.5	1.0	0.7
Number of incorrect matches in round	1.5	2.5	5.9	-1.2	-1.1	-1.5	-1.4	-1.0	-2.2	-1.5	-1.9	-1.0	-2.4	-1.1	-1.6
Hair/balding pattern: Pattern 2	1.5	1.9	5.6	1.0	0.6	-0.5	-0.3	2.1	0.5	2.4	2.0	1.7	1.5	1.1	0.3
Age at last live birth	1.5	2.1	5.4	1.7	1.6	2.3	2.0	-0.8	1.9	0.1	1.0	1.4	1.0	0.6	1.3
Supplements: Vitamin C	1.5	1.8	9.7	-0.9	-0.5	0.8	0.7	-3.1	0.6	-2.2	-1.2	-0.2	-0.5	-1.1	-1.0
Ovarian Cancer	1.4	1.9	5.2	2.1	1.5	0.7	0.7	2.3	0.1	1.9	0.6	1.3	-0.3	1.7	1.4
Schizophrenia (2014)	1.4	3.2	10.2	-2.4	-1.1	-0.6	-0.1	-3.2	-0.9	-3.0	-1.6	-1.6	-1.3	-1.2	-1.6
Lung FEV1/FVC ratio	1.4	7.1	11.1	-3.0	-2.2	-2.4	-1.9	-2.6	-3.0	-3.2	-2.7	-3.3	-2.5	-1.6	-3.0
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	5.5	-1.9	-0.4	-2.3	-0.7	-1.5	-1.1	-1.8	0.6	-0.2	-1.2	-0.5	-0.9
Lung cancer (father)	1.4	1.6	3.8	-1.2	-0.9	-1.0	-0.3	-1.7	-0.7	-1.9	-1.2	-1.2	-1.6	-1.3	-1.4
Birth weight	1.4	3.0	14.1	1.0	2.3	0.6	2.3	0.4	0.8	1.3	1.5	1.3	1.0	3.8	1.5
Emphysema/chronic bronchitis	1.4	1.6	4.2	-0.9	-1.0	0.1	0.0	-1.6	-0.5	-1.7	-1.7	-1.5	-0.4	-2.0	-1.4
Financial situation satisfaction	1.4	1.7	4.3	1.6	1.2	1.4	0.5	0.4	1.5	1.1	1.1	2.1	2.0	0.1	1.3
Pain type(s) experienced in last month: Hip pain	1.4	1.8	4.4	1.4	1.5	1.2	1.2	-0.2	1.9	0.2	1.4	1.9	2.1	0.2	1.0
Medication: Bendroflumethiazide	1.4	2.2	4.7	2.2	1.9	1.5	1.7	0.4	2.0	1.0	0.8	2.0	1.1	0.6	1.0
Illnesses of father: High blood pressure	1.4	1.7	4.9	1.8	1.6	0.3	0.2	2.2	0.4	1.4	1.5	1.5	0.7	0.2	1.4
Age started oral contraceptive pill	1.4	1.7	3.7	-1.4	-1.6	-0.7	-1.4	-0.9	-0.9	-1.2	-1.6	-1.5	-0.3	-1.9	-1.5
Hayfever, allergic rhinitis or eczema	1.3	2.7	4.5	1.9	1.7	1.6	1.6	1.1	1.9	1.9	1.1	2.1	1.9	1.2	1.5
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	5.4	-0.8	-0.5	-2.3	-0.8	1.2	-2.1	0.5	0.6	-1.3	-1.2	0.6	-1.3
Financial difficulties in last 2 years	1.3	1.8	3.8	2.0	0.9	1.3	0.2	1.6	1.4	1.7	1.3	1.9	0.7	0.6	1.3
Blood clot in the leg (DVT)	1.3	1.6	6.9	1.4	1.0	-0.6	0.5	2.6	0.2	1.8	0.7	1.3	0.6	1.3	1.2
Medication: Paracetamol	1.3	2.2	4.9	1.8	1.6	1.9	1.4	0.8	2.2	1.3	0.9	1.6	1.3	0.6	1.5
Body Mass Index (BMI) (2010)	1.2	1.6	4.2	2.1	1.0	0.7	0.8	1.3	1.4	2.0	0.3	1.7	1.3	1.0	0.5
Systolic Blood Pressure	1.2	5.8	16.8	4.1	3.3	1.3	1.2	2.8	2.1	2.3	2.5	3.2	1.2	0.5	1.9
Medication for hormone replacement therapy	1.2	1.4	3.4	-1.3	-1.5	-1.3	-1.4	-0.1	-1.1	-0.7	-0.2	-0.7	-1.5	-1.9	-1.1
Taking other prescription medications	1.2	1.8	4.4	2.1	0.8	2.1	1.7	1.0	1.6	1.6	0.3	1.2	0.9	-0.5	0.7
Noisy workplace	1.2	1.5	4.4	2.1	1.3	1.5	1.3	1.3	1.3	1.3	0.4	1.0	0.6	0.7	0.8
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	4.6	-1.0	-1.0	-0.9	0.0	-1.2	-1.4	-1.1	-2.1	-1.7	-0.7	0.1	-1.4
Medication: Blood pressure	1.2	2.3	8.5	2.9	2.1	0.8	1.0	2.0	1.0	1.4	0.7	1.9	-0.2	0.8	1.4
Reaction Time	1.1	2.0	6.1	-1.6	-1.2	-0.4	-0.2	-2.5	-0.5	-2.1	-1.5	-0.4	-1.1	-1.7	-1.6
Mean Putamen Volume	1.1	1.3	2.4	-1.1	-0.5	-1.4	-0.9	-1.2	-0.8	-1.5	-0.6	-0.4	-1.5	-1.6	-1.4
Eye problems/disorders: Diabetes related eye disease	1.1	1.3	5.8	2.4	1.1	1.0	1.1	0.6	1.0	1.1	-0.6	1.6	0.1	0.6	-0.2
Exposure to tobacco smoke at home	1.1	1.2	4.2	0.9	0.2	1.7	0.4	-1.3	0.7	-0.7	-1.4	1.3	-0.2	-2.0	-0.3
Mean time to correctly identify matches	1.1	2.1	4.1	-1.8	-1.5	-0.9	-0.6	-2.0	-1.1	-2.0	-1.7	-0.6	-1.7	-1.3	-1.4
Schizophrenia (2018)	1.0	2.1	5.6	-1.7	-0.7	-0.8	-0.2	-2.3	-0.9	-2.4	-1.5	-1.1	-1.6	-1.3	-1.5
Bipolar Disorder (2011)	1.0	1.0	5.2	-0.9	-0.2	0.5	0.6	-2.3	0.5	-1.6	-0.5	-0.6	-0.0	-0.9	-1.0
Systolic blood pressure, automated reading	1.0	2.9	10.1	3.2	1.9	1.3	0.5	2.2	1.6	1.9	0.5	2.1	0.9	0.3	1.5
Hearing difficulty/problems with background noise	1.0	1.6	3.0	1.1	1.1	0.6	0.7	0.9	1.2	1.2	1.7	1.3	1.5	1.5	1.6
Allergy	1.0	2.4	3.9	-1.9	-1.7	-1.4	-1.5	-1.5	-1.6	-1.8	-0.9	-2.0	-1.5	-0.7	-1.5
Pulse wave reflection index	1.0	1.2	3.4	-0.5	-1.1	-0.5	-0.6	-0.6	-0.5	-0.7	-1.8	-1.6	-0.9	-1.3	-1.6
High blood pressure (siblings)	1.0	1.4	3.4	1.3	1.3	0.2	-0.5	1.7	0.8	1.1	1.3	1.8	0.8	0.6	1.4
Eye problems/disorders: Cataract	1.0	1.2	2.8	-1.4	-1.0	-1.2	-0.5	-0.7	-1.7	-1.0	-0.6	-1.5	-1.5	0.1	-0.5
Supplements: Calcium	1.0	1.1	2.9	1.3	1.7	1.1	1.5	-0.0	1.2	0.2	1.0	1.6	-0.1	0.5	0.6
Alcohol drinker status: Previous	1.0	1.2	3.2	1.2	1.8	0.8	0.9	-0.5	0.8	-0.0	1.2	1.8	0.7	-1.3	0.2
Crohns Disease (2017)	0.9	1.9	4.1	-1.9	-2.0	-1.2	-1.7	-0.6	-1.3	-0.4	-0.7	-1.6	-0.3	-1.2	-2.0
Hearing difficulty/problems: Yes	0.9	1.4	3.3	1.4	0.9	1.1	1.8	0.4	1.2	1.2	0.3	1.1	1.6	1.2	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	4.3	-1.2	-0.2	-0.8	0.1	-2.1	-0.4	-2.0	0.5	0.2	-1.2	-1.1	-0.8
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.4	1.2	1.1	0.6	0.8	0.5	1.1	1.0	1.5	1.5	1.3	-0.2	1.0
Suffer from ‘nerves’	0.9	1.4	6.1	0.8	1.4	-0.0	0.5	1.4	0.3	1.1	2.5	0.6	0.1	1.5	1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	3.2	0.7	1.1	1.1	1.1	-0.9	1.3	0.1	0.6	1.2	1.8	0.1	-0.0
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	5.0	-1.4	-0.2	0.2	0.3	-2.2	-0.2	-1.9	0.4	-0.5	-0.8	-0.7	0.3
Angina	0.8	1.0	2.7	-0.8	-1.2	-1.7	-0.6	0.3	-1.3	0.1	-0.9	-1.3	-0.1	0.2	-1.5
Diabetes (father)	0.8	1.0	3.1	1.3	1.1	0.3	1.0	1.8	0.7	1.2	1.1	0.6	0.4	0.6	1.1
Serious illness, injury or assault to yourself	0.8	0.9	2.9	1.2	0.4	0.5	0.5	1.7	0.4	1.7	0.5	0.9	-0.1	1.0	0.9
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	2.8	0.9	1.0	1.3	0.9	0.2	0.8	1.0	-0.2	1.7	1.2	0.8	1.1
Worrier / anxious feelings	0.8	1.4	4.9	1.1	1.3	0.0	0.0	1.7	0.9	1.5	2.2	1.5	1.0	0.0	0.5
Medication: Blood pressure	0.8	1.4	3.2	1.7	1.0	1.3	0.6	0.7	1.3	1.2	0.7	1.8	0.8	1.2	1.3
Smoking status: Current	0.8	1.2	7.8	-0.2	-0.9	0.6	-0.5	-0.7	0.4	-1.0	-1.7	-0.3	-0.3	-2.8	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	5.7	0.1	-0.4	0.6	0.4	-1.3	0.2	-1.1	-1.3	0.5	-0.7	-2.4	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	5.0	0.9	0.7	-1.0	0.0	2.2	-0.1	1.4	0.6	1.0	0.4	1.0	0.9
Bipolar Disorder or Schizophrenia	0.7	1.8	7.8	-1.5	-0.4	-0.0	0.4	-2.8	-0.2	-2.2	-1.0	-0.9	-1.0	-1.2	-1.4
HDL Cholesterol	0.7	1.2	2.7	-1.0	-0.8	-0.5	-0.5	-1.6	-0.9	-1.6	-1.1	-1.0	-1.5	-1.2	-0.7
Waist Hip Ratio (WHR)	0.7	3.4	9.9	0.7	1.5	2.8	3.1	-2.2	2.5	-0.3	0.8	1.7	1.8	1.1	0.9
Medication: Co-codamol	0.7	0.8	2.2	1.5	0.9	1.1	0.3	0.6	1.4	0.8	0.3	0.8	1.1	-0.1	0.1
Maternal smoking around birth	0.7	1.1	3.5	0.9	-0.7	1.0	-0.7	-0.5	1.5	0.4	-0.4	1.2	1.3	-1.9	-0.7
Medication: Levothyroxine sodium	0.7	1.2	2.5	1.1	0.9	1.4	0.9	0.2	1.6	0.8	1.4	0.9	1.5	0.3	1.2
Sitting height	0.7	5.1	14.9	-3.1	-2.0	-3.9	-1.8	-0.5	-3.2	-1.4	0.3	-2.6	-1.7	-0.5	-2.6
Time employed in main current job	0.7	0.8	2.1	-0.9	-1.3	-0.5	-1.2	-0.0	-0.9	-0.2	-1.0	-0.9	0.2	-1.5	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.6	-1.2	-0.7	-0.8	-1.2	-0.9	-0.6	-1.3	0.7	-0.3	-0.6	-1.1	-0.2
Eye problems/disorders: None of the above	0.7	0.8	2.7	0.5	1.0	0.8	0.7	-0.1	1.6	0.4	0.9	1.3	1.4	-0.5	0.2
Neck or shoulder pain in last month	0.7	1.0	2.2	0.9	1.1	1.0	1.2	0.6	1.1	0.7	1.1	0.9	1.5	0.4	0.9
Commuting to job workplace: Public transport	0.7	0.8	3.6	-0.7	-0.3	-0.6	-0.4	-0.4	-1.4	-0.8	-0.4	-1.9	-1.0	-0.4	-1.0
Supplements: Fish oil (including cod liver oil)	0.7	0.9	1.9	-1.1	-0.7	-1.4	-0.2	-1.2	-0.7	-1.0	-0.1	-1.1	-1.0	0.7	-1.1
Medication: Paracetamol	0.7	1.1	2.5	1.5	0.8	1.3	1.3	0.8	1.6	1.3	0.4	0.7	0.8	0.3	0.6
Triglycerides	0.6	1.0	2.3	1.1	-0.6	-0.6	-1.3	1.2	-0.8	0.2	-1.5	-0.4	-1.0	-1.5	-0.6
Allergy or Eczema	0.6	1.5	3.5	1.9	1.1	1.6	1.2	0.9	1.2	1.5	0.1	1.7	1.0	0.7	0.8
Sensitivity / hurt feelings	0.6	1.0	3.8	1.3	1.2	0.0	0.5	2.0	0.3	1.2	1.4	0.7	0.5	0.1	1.0
Frequency of depressed mood in last 2 weeks	0.6	0.8	3.3	0.2	0.5	0.4	0.5	-1.6	0.5	-1.2	0.3	1.8	-0.6	-1.0	-0.1
Vitamin and mineral supplements	0.6	0.8	4.5	-0.0	-0.7	-0.9	-0.7	2.1	-0.6	1.3	0.3	-0.5	0.6	0.3	-0.2
Townsend deprivation index at recruitment	0.6	0.8	4.5	0.4	-0.9	-0.5	-1.7	0.4	-0.3	0.0	-0.1	0.2	-0.1	-2.1	-1.0
Falls in the last year	0.6	0.7	2.1	1.4	0.6	0.6	0.9	1.1	0.8	1.2	0.5	0.3	0.7	0.4	1.0
Qualifications: A levels/AS levels or equivalent	0.6	1.4	4.2	0.4	1.7	1.0	2.1	-1.5	1.0	-0.7	0.9	0.1	0.0	1.8	0.7
Length of working week for main job	0.6	0.7	3.0	0.4	-0.8	-0.4	-1.1	1.7	-0.4	0.9	-0.9	-1.0	0.4	0.4	-0.1
Glaucoma (self-reported)	0.6	0.7	2.0	1.1	0.4	1.4	0.3	0.5	0.7	0.9	0.2	0.7	0.9	1.1	1.0
Forced vital capacity (FVC), Best measure	0.6	2.3	7.4	0.4	1.7	0.1	1.5	0.3	0.7	1.3	2.7	1.5	0.9	2.7	1.6
Shortness of breath walking on level ground	0.6	0.7	2.1	1.2	0.5	0.4	0.3	1.5	0.6	1.3	0.6	0.6	1.1	-0.2	0.4
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.7	0.0	-0.2	0.7	0.6	-1.6	0.6	-1.0	-1.2	0.5	-0.1	-1.2	-0.7
Medication: Omeprazole	0.6	0.7	2.7	-0.0	0.2	0.8	0.8	-1.4	0.1	-1.3	-0.5	0.6	-0.4	-1.6	0.2
Leg pain on walking	0.6	0.8	2.0	1.2	1.1	-0.3	0.4	1.4	0.5	1.1	0.6	0.8	1.1	0.4	-0.4
Ever taken oral contraceptive pill	0.6	0.6	2.3	0.3	-0.1	-1.1	-1.5	1.2	-0.4	0.7	1.4	0.4	0.4	0.1	-0.1
Eye problems/disorders: Glaucoma	0.6	0.7	1.8	1.0	0.4	1.3	1.0	0.3	0.8	0.6	-0.5	0.4	0.7	1.3	0.7
Medication: Lisinopril	0.6	0.8	3.5	1.0	1.4	0.7	1.9	-0.8	0.8	-0.4	-0.1	0.5	-0.6	0.5	-0.1
Ever smoked	0.6	1.1	2.0	-0.9	-1.3	0.3	-0.2	-1.4	-0.5	-1.2	-1.1	-1.3	-1.2	-1.2	-1.2
Diastolic blood pressure, automated reading	0.6	1.8	5.1	2.3	1.9	1.0	0.7	1.3	1.4	1.2	0.6	1.8	0.7	0.5	1.4
Basal cell carcinoma (self-reported)	0.6	0.8	3.8	-0.2	-0.8	-0.7	-1.9	1.1	-0.6	0.0	0.6	-0.3	0.1	-1.4	-0.6
Depression (Nagel 2018)	0.5	0.8	3.4	-0.6	-0.2	-0.2	0.3	-1.8	-0.4	-1.7	-0.2	0.6	-1.2	-0.3	-0.3
Alzheimer’s Disease (in mother)	0.5	0.5	1.9	-0.8	-0.7	-1.0	-1.0	-0.6	-1.4	-0.4	-0.7	-0.0	-0.8	-0.3	-0.2
Major Depression (MDD)	0.5	0.6	1.8	0.9	1.1	-0.2	0.2	0.6	0.3	0.6	1.3	1.1	0.5	0.9	0.7
Crohns Disease (2012)	0.5	0.8	3.2	-1.2	-0.8	0.4	0.1	-1.8	0.4	-0.8	-0.4	-0.3	0.5	-1.2	-1.0
HbA1C	0.5	0.5	2.8	-0.4	-1.7	-0.1	-1.5	0.2	-0.4	0.3	-0.6	-0.4	-0.2	0.0	-0.6
Neuroticism (2016)	0.5	0.7	2.0	0.7	0.7	0.1	0.9	1.3	0.6	1.0	1.4	0.6	-0.1	0.4	0.9
Smoking Status	0.5	1.1	4.6	0.9	-0.3	2.1	0.6	-1.1	1.2	-0.4	-1.0	0.3	0.3	-1.8	0.2
Hand grip strength (left)	0.5	1.4	4.5	-1.8	-0.7	-2.1	-0.8	-0.2	-1.7	-0.9	0.6	-1.3	-1.2	0.5	-0.8
Relative age of first facial hair	0.5	1.0	3.2	1.8	1.6	0.9	0.9	1.1	1.0	0.6	0.5	0.8	0.1	0.3	0.9
Age when periods started (menarche)	0.5	1.1	5.3	-0.6	-1.5	2.3	-0.2	-0.9	0.6	-0.2	-1.2	-1.2	0.1	-1.2	0.5
Multivitamins +/- minerals	0.5	0.6	2.6	-0.9	-0.0	-0.3	-1.0	-1.6	-0.2	-1.3	-0.1	0.1	-0.7	-0.8	-0.2
Stomach or abdominal pain in last month	0.5	0.6	1.9	-0.9	-1.2	-1.0	-1.4	-0.2	-0.6	-0.4	-0.1	-0.4	-0.2	-0.7	-1.0
Alcohol usually taken with meals	0.5	0.8	2.2	0.2	0.9	0.8	1.4	-1.2	0.7	-0.4	0.5	0.3	0.6	1.5	1.3
Had menopause	0.5	0.6	3.0	-0.5	-1.0	-0.4	0.3	-0.6	-0.5	-0.5	-1.7	-0.8	-0.3	-0.5	-1.0
Medication: Ramipril	0.5	0.6	2.0	0.7	-0.2	0.3	-0.9	1.4	0.1	1.4	0.3	0.1	1.0	0.7	0.8
Illnesses of siblings	0.5	0.8	2.3	-1.1	-1.0	-0.9	0.2	-0.8	-0.8	-0.4	-0.5	-1.5	-1.0	0.6	-1.0
Father’s age at death	0.5	0.7	3.1	0.8	0.4	0.8	0.8	1.6	-0.0	1.8	-0.4	-0.0	0.3	0.6	0.6
Medication: Cholesterol lowering	0.5	0.8	1.3	1.1	1.1	0.8	0.9	0.8	0.7	0.9	0.6	0.9	0.5	1.1	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	3.3	0.3	0.5	-1.0	-0.1	1.6	-0.2	0.9	1.8	0.4	-0.0	-0.2	0.3
Age at first live birth	0.5	0.9	3.4	0.3	-0.2	1.8	0.9	-1.7	0.8	-0.9	-1.2	-0.2	0.4	-0.6	-0.2
Angina (self-reported)	0.5	0.7	2.2	-0.6	-1.1	-1.5	-0.5	0.3	-1.1	0.2	-0.6	-1.0	0.1	0.2	-1.3
Medication: Ibuprofen	0.5	0.6	2.1	0.0	-0.7	-0.9	-0.7	1.5	-0.3	1.4	0.8	-0.3	-0.0	0.1	-0.7
Pulse rate, automated reading	0.5	1.5	2.8	-1.3	-1.3	-1.4	-1.2	-0.6	-1.3	-1.3	-0.5	-1.0	-1.7	-1.5	-0.8
Ever had bowel cancer screening	0.5	0.6	2.8	-0.2	-1.0	0.4	-1.1	-0.1	-0.2	-0.4	-0.9	-0.5	-0.2	-1.7	-0.6
Back pain experienced in last month	0.5	0.7	1.8	-0.1	-0.3	0.6	0.2	-1.3	0.0	-1.2	-1.2	-0.3	-0.4	-1.2	-1.0
Medication: Gliclazide	0.5	0.5	2.0	1.0	0.6	0.9	1.3	-0.2	0.3	-0.3	-1.4	0.1	-0.1	0.6	0.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.7	-0.4	-0.6	-1.1	-1.6	1.3	-0.7	0.8	0.4	-0.1	0.1	0.4	-0.3
Unable to work because of sickness or disability	0.5	0.7	3.6	0.8	0.4	1.0	0.6	-0.7	1.0	-0.4	-0.0	0.8	0.2	-1.9	-0.3
Pain experienced in last month	0.5	0.8	2.9	-0.5	-1.6	-0.2	-1.7	0.2	-0.4	0.2	-1.2	-0.3	-0.1	-1.2	-0.5
Pack years of smoking	0.5	0.7	1.9	-0.4	-0.8	-1.1	-0.1	-0.1	-0.6	-0.5	-0.6	-1.1	-1.0	-1.4	-1.4
Irritable Bowel Disease (IBD)	0.4	0.9	2.5	-1.6	-1.4	-0.7	-1.3	-0.0	-0.6	0.0	-0.2	-1.3	0.5	-0.5	-1.1
Ulcerative Colitis (UC)	0.4	0.7	2.5	-1.6	-1.2	-0.8	-1.0	-0.0	-0.6	-0.4	-0.3	-1.5	0.2	-0.3	-0.4
Primary Biliary Cirrhosis	0.4	0.6	1.5	-0.1	0.8	1.2	1.1	-1.1	0.2	-0.6	-0.8	-0.1	-0.5	1.2	0.4
Blood Eosinophil Count	0.4	2.9	17.2	2.0	0.2	4.1	1.3	0.9	1.3	1.7	-1.6	0.9	0.8	-0.2	1.7
Blood Red Count	0.4	3.9	14.7	1.6	1.4	3.8	1.8	-1.4	3.0	0.2	0.7	2.0	1.8	0.2	2.4
BMI	0.4	2.1	5.2	-1.6	-2.3	-1.9	-1.9	-0.4	-1.8	-0.6	-0.8	-1.8	-0.7	-0.6	-1.2
Hypothyroidism (self reported)	0.4	1.0	2.6	0.2	0.4	1.0	1.3	-0.3	1.6	0.7	1.4	0.0	1.4	0.8	1.2
Chronotype (morning person)	0.4	0.9	2.7	0.7	1.5	0.2	1.4	0.3	0.5	0.5	1.1	0.8	0.2	1.6	1.0
Current tobacco smoking	0.4	0.7	4.6	0.2	-0.4	0.9	-0.1	-0.5	0.6	-0.6	-1.5	-0.0	-0.2	-2.1	-0.2
High blood pressure (mother)	0.4	0.6	1.8	-1.3	-0.9	-0.6	-1.2	-0.9	-0.2	-1.1	0.2	-0.2	-0.1	-0.8	-0.2
Pain all over the body in last month	0.4	0.4	1.7	0.7	0.8	-0.3	0.6	0.5	0.3	0.5	0.7	1.3	0.4	0.3	0.8
Diabetes (self-reported)	0.4	0.6	1.3	1.0	0.4	1.1	1.0	0.0	0.6	0.3	-0.4	0.8	-0.4	1.1	0.7
Fluid intelligence score	0.4	0.8	2.7	0.2	0.6	0.9	1.2	0.3	1.7	0.4	0.7	0.5	1.4	0.8	0.7
Pulse rate	0.4	0.6	2.1	0.4	1.3	0.2	0.7	0.1	0.8	0.2	1.4	0.7	0.3	0.8	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.6	2.2	-0.0	-0.6	-0.7	-0.6	1.5	-0.2	1.5	0.8	-0.2	0.1	0.2	-0.5
Medication: Lansoprazole	0.4	0.5	1.5	1.0	-0.0	1.2	-0.0	-0.3	0.8	0.1	-1.0	1.0	0.2	-0.8	-0.4
Illnesses of mother	0.4	0.5	1.5	1.2	0.6	0.6	0.9	0.9	0.2	1.0	-0.1	0.2	0.2	0.6	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	5.5	-0.6	1.2	-0.5	1.2	-0.9	-0.1	-0.1	1.8	0.5	0.1	2.4	0.9
Peak expiratory flow (PEF)	0.4	1.0	2.8	-0.3	1.3	-0.6	1.5	-1.1	-0.1	-0.5	1.6	0.7	0.2	1.7	0.4
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.2	-1.5	0.0	-1.0	-0.4	-0.9	-0.8	-0.6	1.1	-0.8	-0.3	0.7	-0.4
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.8	-0.1	0.5	-1.4	-0.5	-0.1	-0.3	-0.4	1.2	0.4	-0.8	-0.1	-0.8
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.6	-1.2	-1.0	-0.8	-0.7	-0.2	-0.9	-0.6	-0.3	-1.3	-0.3	-0.5	-0.7
Medication: Ventolin 100micrograms inhaler	0.4	0.6	1.8	-1.1	-0.7	-1.2	-1.4	0.1	-0.3	-0.4	0.8	-0.9	-0.2	-0.4	-0.3
Exposure to tobacco smoke outside home	0.4	0.5	1.3	-0.8	-0.5	-1.1	-1.1	-0.3	-0.5	-0.7	0.3	0.1	-0.8	-0.8	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.9	0.2	0.6	0.1	1.4	-0.1	0.9	0.6	1.2	0.7	0.2	1.0	0.2
Family relationship satisfaction	0.4	0.5	1.6	0.8	0.7	-0.0	0.2	1.2	0.4	1.2	0.9	0.3	0.5	0.7	0.5
Smoking status: Previous	0.4	0.5	2.5	0.4	0.1	1.6	0.6	-0.9	1.1	0.2	0.4	0.6	0.7	0.5	0.5
Arm fat percentage (left)	0.4	1.5	3.8	-0.6	-1.0	-0.5	-0.8	-1.6	-0.8	-1.8	-1.9	-0.8	-1.1	-1.5	-1.0
Average weekly champagne plus white wine intake	0.4	0.5	1.8	-0.8	-0.7	-0.6	-1.3	0.1	-1.0	-0.3	0.6	-0.8	-0.9	-0.1	0.3
Hearing aid user	0.4	0.5	2.2	0.9	0.1	1.5	0.5	0.1	0.7	0.1	-0.3	-0.3	0.7	-0.9	0.8
Risk taking	0.4	0.5	2.3	0.3	0.1	1.5	0.5	-0.9	1.0	-0.2	-0.8	0.1	0.2	-1.0	-0.2
Bipolar Disorder (2018)	0.3	0.5	2.5	-0.3	0.3	1.0	1.0	-1.6	0.8	-0.6	0.3	-0.1	0.3	-0.3	-0.3
Depressed Affect (Nagel 2018)	0.3	0.5	2.6	-0.3	-0.2	0.7	0.5	-1.6	-0.2	-1.3	-0.7	0.1	-0.3	-0.7	-0.0
Alzheimer’s Disease (in father)	0.3	0.4	1.3	0.7	0.9	0.6	1.1	-0.8	0.5	-0.5	0.1	0.3	-0.2	0.3	-0.3
Age at First Birth	0.3	0.5	1.7	0.0	-0.8	0.6	-0.9	0.3	0.8	0.4	0.1	0.0	1.3	-1.3	0.3
Lupus	0.3	0.5	2.2	0.4	-1.0	0.4	-0.2	-0.0	-0.6	0.2	-1.5	-1.2	-0.3	-0.7	-0.7
Rheumatoid Arthritis	0.3	0.4	1.8	-0.1	-0.5	0.0	-1.1	0.7	-0.1	0.6	0.6	-0.4	1.3	0.5	0.5
Blood White Count	0.3	1.9	9.4	1.4	0.7	3.1	1.3	-0.3	1.3	0.8	0.0	1.7	0.2	-0.2	2.0
Ever had hysterectomy (womb removed)	0.3	0.3	1.6	-0.5	0.1	-1.2	-0.9	-0.2	-0.7	-0.1	0.8	0.3	0.2	0.1	-0.3
Pack years adult smoking proportion	0.3	0.5	1.5	-0.3	-0.4	-0.8	0.1	-0.1	-0.4	-0.5	-0.3	-1.0	-0.9	-1.2	-1.0
Leg fat-free mass (left)	0.3	1.4	6.2	-0.9	0.4	-2.5	-0.2	-0.3	-1.8	-0.7	1.0	-0.3	-1.2	1.6	-0.5
Trunk fat percentage	0.3	1.2	3.3	-0.6	-0.9	-0.2	-0.6	-1.8	-0.1	-1.8	-1.4	-0.7	0.1	-1.7	-0.7
Hand grip strength (right)	0.3	0.7	1.9	-0.7	0.1	-1.4	-0.3	1.0	-1.3	0.4	0.7	-0.7	-0.4	1.3	0.3
Supplements: Glucosamine	0.3	0.4	1.2	-0.1	0.6	-0.2	1.1	-0.9	0.4	-0.6	-0.4	0.0	-0.5	1.0	-0.7
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.5	-1.0	-0.3	-1.2	-0.9	0.2	-0.5	-0.1	0.3	-0.2	0.2	0.4	-0.2
Impedance of leg (left)	0.3	1.2	3.9	0.5	0.3	1.8	0.7	-0.5	1.9	0.2	0.3	0.5	2.0	-1.5	0.6
Leg predicted mass (left)	0.3	1.3	6.0	-0.8	0.4	-2.4	-0.1	-0.2	-1.7	-0.7	1.1	-0.3	-1.1	1.7	-0.5
Past tobacco smoking	0.3	0.6	2.5	0.4	0.9	-1.1	-0.1	1.6	-0.5	0.8	0.7	0.3	0.1	0.6	0.6
Nervous feelings	0.3	0.6	2.0	0.6	0.6	0.5	-0.1	1.3	0.1	1.1	1.4	0.1	0.4	0.1	0.9
Heart attack	0.3	0.4	0.9	-0.6	-0.9	-0.5	-0.4	-0.2	-0.8	-0.4	-1.0	-0.4	-0.6	0.5	-0.1
Neuroticism score	0.3	0.5	1.9	0.4	0.9	0.7	0.6	-0.3	0.5	0.3	1.4	1.0	0.9	-0.2	0.6
Arm fat percentage (right)	0.3	1.1	2.9	-0.4	-0.9	-0.4	-0.7	-1.3	-0.8	-1.6	-1.7	-0.8	-1.1	-1.3	-0.8
Trunk fat-free mass	0.3	2.0	8.0	-0.0	0.8	-2.4	0.4	1.2	-1.6	0.8	2.0	0.1	-0.7	2.8	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.6	1.6	0.8	0.6	0.4	1.0	0.3	0.4	0.5	1.2	1.3	-0.2	0.3	0.9
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	3.0	-0.8	1.0	-0.9	0.8	-1.2	-0.7	-0.6	1.7	-0.0	-0.2	1.6	0.2
Happiness	0.3	0.4	0.7	-0.7	-0.3	-0.7	-0.8	-0.4	-0.8	-0.7	0.7	-0.4	-0.2	-0.7	0.2
Mouth/teeth dental problems: Dentures	0.3	0.5	1.5	0.8	0.5	0.7	0.7	0.5	0.9	0.5	0.7	0.5	1.2	0.1	0.9
Prospective memory result	0.3	0.4	1.8	0.1	-0.2	-0.7	-0.3	-0.5	-0.5	-0.4	-0.6	0.1	-0.6	-0.8	-1.4
Pulse wave Arterial Stiffness index	0.3	0.4	1.9	-0.1	-0.5	-0.6	-0.1	-0.4	0.1	-0.4	-0.9	-0.8	-0.3	-0.4	-1.4
Impedance of arm (left)	0.3	1.3	6.3	-0.6	-0.2	0.6	-0.4	-1.9	0.3	-1.7	-0.7	0.1	0.2	-2.5	-1.0
Trunk predicted mass	0.3	2.0	7.7	-0.1	0.8	-2.5	0.3	1.1	-1.7	0.7	2.0	0.1	-0.7	2.8	0.1
Loud music exposure frequency	0.3	0.3	1.4	-0.4	-0.0	0.7	0.3	-1.0	1.2	-0.3	0.5	0.4	0.5	0.1	0.4
Gout (self-reported)	0.3	0.3	0.9	0.6	-0.0	0.4	-0.4	0.9	0.7	0.9	0.1	1.0	0.5	-0.3	0.5
Body fat percentage	0.3	1.2	3.1	-0.4	-0.9	0.1	-0.5	-1.8	-0.1	-1.7	-1.7	-0.7	-0.1	-1.7	-0.6
Worry too long after embarrassment	0.3	0.5	1.5	-0.1	-0.0	-0.1	-1.2	1.2	-0.1	0.9	1.0	0.1	0.3	0.5	0.9
Number of children fathered	0.3	0.3	2.0	0.1	0.0	-0.6	-0.8	0.2	-0.3	0.0	0.0	-0.3	0.2	1.4	0.5
Health satisfaction	0.3	0.4	1.8	-0.3	-0.1	-1.4	-0.4	0.6	-0.8	0.2	0.7	-0.2	-0.5	-0.7	-0.8
Medication for pain relief, constipation, heartburn	0.3	0.5	1.8	-0.8	-0.1	-1.2	-0.6	0.2	-1.3	-0.3	-0.4	-0.9	-0.2	0.8	-0.1
Arm predicted mass (right)	0.3	1.3	6.0	-0.2	0.6	-2.1	0.3	0.9	-1.1	0.7	1.7	-0.0	-0.1	2.4	0.2
Had major operations	0.3	0.3	0.8	0.1	0.2	-0.9	0.2	-0.6	-0.4	-0.4	0.3	-0.0	-0.9	-0.8	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	3.2	0.0	1.1	-1.1	0.5	0.4	-0.3	0.3	1.8	0.1	0.2	0.9	0.0
Whole body fat-free mass	0.3	1.7	6.9	-0.3	0.8	-2.4	0.3	0.7	-1.6	0.3	1.9	0.0	-0.7	2.6	0.0
Leg fat-free mass (right)	0.3	1.4	6.1	-0.8	0.5	-2.5	-0.1	-0.2	-1.6	-0.7	1.2	-0.1	-1.1	1.8	-0.5
Average weekly red wine intake	0.3	0.5	2.7	-0.9	-0.5	0.2	-0.0	-1.6	0.6	-1.1	-0.5	-0.1	0.3	-0.0	-0.2
Diabetes diagnosed by doctor	0.3	0.5	1.3	1.1	0.1	0.9	0.8	0.6	0.4	0.7	-0.7	0.7	-0.5	0.9	0.4
Medication for cholesterol	0.3	0.5	2.1	-0.7	0.4	0.6	0.6	-1.2	0.3	-0.4	0.4	-0.1	1.4	0.9	0.3
Medication: Aspirin	0.3	0.4	1.2	0.3	-0.1	0.6	0.7	-1.0	1.1	-0.1	-0.3	1.0	0.2	0.0	-0.2
Whole body water mass	0.3	1.6	6.5	-0.4	0.7	-2.4	0.2	0.6	-1.6	0.2	1.8	-0.0	-0.7	2.5	-0.0
Leg predicted mass (right)	0.3	1.3	5.9	-0.9	0.5	-2.4	-0.2	-0.3	-1.6	-0.7	1.2	-0.1	-1.0	1.8	-0.5
Arm fat mass (left)	0.3	1.1	2.2	-0.9	-0.9	-1.5	-1.1	-1.0	-1.3	-1.3	-1.0	-0.9	-1.1	-0.5	-1.0
Guilty feelings	0.3	0.5	2.5	-0.6	0.2	0.8	0.5	-1.6	0.9	-0.6	0.5	0.6	0.8	-0.4	-0.0
Alcohol drinker status: Never	0.3	0.3	1.0	0.4	0.1	0.0	-0.4	0.9	0.2	0.5	0.5	0.9	0.5	0.3	1.0
Basal metabolic rate	0.3	1.5	6.4	-0.6	0.5	-2.5	0.0	0.3	-1.7	-0.1	1.4	-0.2	-0.9	2.1	-0.2
Arm fat-free mass (left)	0.3	1.6	6.7	-0.4	0.4	-2.4	0.0	1.1	-1.4	0.7	1.8	-0.2	-0.3	2.6	0.2
Average weekly beer plus cider intake	0.3	0.4	1.0	0.7	0.8	0.2	-0.2	1.0	0.3	0.8	0.7	0.9	0.3	-0.0	0.5
Arm predicted mass (left)	0.3	1.5	6.2	-0.2	0.6	-2.1	0.3	1.1	-1.2	0.8	1.7	-0.2	-0.2	2.5	0.1
Worry (Nagel 2018)	0.2	0.4	1.7	-0.4	0.3	-0.8	-0.7	0.7	-0.9	0.3	1.3	-0.2	-0.1	-0.2	-0.1
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.2	-0.2	0.5	0.9	1.1	-0.3	1.1	0.0	0.5	0.5	0.7	0.7	0.4
Coronary Artery Disease (CAD)	0.2	0.3	1.5	-0.1	-0.3	-0.2	0.1	0.5	-0.5	0.4	-0.4	-0.7	-1.2	-0.1	-0.1
Ulcerative Colitis	0.2	0.3	1.8	-1.3	-0.3	-0.0	-0.1	-0.6	0.1	-0.6	0.0	-0.6	0.8	-0.0	0.0
Blood Platelet Count	0.2	1.8	7.8	0.2	-1.5	0.1	-1.8	-0.4	-0.5	-0.7	-2.2	-0.9	0.3	-2.8	-1.3
Height	0.2	3.4	13.7	-1.5	0.9	-3.7	1.1	0.1	-2.2	-0.1	2.2	-0.3	-0.5	3.5	-0.8
Respiratory disease	0.2	0.3	1.2	0.5	0.5	0.8	0.1	-0.2	1.0	-0.3	0.3	0.4	0.4	-1.1	0.5
Tanning	0.2	2.1	3.6	1.9	1.6	1.5	1.8	1.1	1.5	1.6	0.6	0.7	1.0	1.7	1.5
Diabetes (mother)	0.2	0.2	0.9	-0.3	0.1	0.0	-0.6	0.1	-0.7	-0.3	0.2	-0.6	-0.9	0.3	0.6
Severe depression (siblings)	0.2	0.2	0.7	-0.0	0.0	-0.4	-0.4	0.8	0.3	0.7	0.8	0.6	0.2	0.6	0.3
Impedance of leg (right)	0.2	0.9	2.8	0.4	0.1	1.7	0.6	-0.3	1.5	0.3	0.2	0.3	1.7	-1.5	0.5
Relative age voice broke	0.2	0.3	1.1	0.7	1.1	0.1	0.8	-0.5	0.3	-0.3	0.3	0.7	-0.5	-0.3	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.2	1.2	-0.2	-0.2	0.4	0.2	-0.1	0.6	0.3	0.6	1.1	0.5	-0.6	0.4
Had other major operations	0.2	0.2	1.1	0.4	-0.2	0.7	1.1	0.1	0.4	-0.0	-0.7	-0.4	0.2	-0.0	-0.1
Forced vital capacity (FVC)	0.2	0.9	5.0	-0.3	1.1	-0.7	0.6	-0.2	-0.4	0.5	2.2	0.5	0.1	1.5	0.5
Mouth/teeth dental problems	0.2	0.3	1.6	-0.2	-0.4	0.6	-0.2	-0.7	-0.3	-0.3	-1.3	-0.5	-0.2	-0.2	-0.1
Medication: Simvastatin	0.2	0.3	1.2	0.4	0.6	0.1	0.3	0.3	0.6	0.3	0.4	0.2	1.0	1.1	0.2
Hip circumference	0.2	0.6	3.0	-0.2	-0.3	-1.1	-0.9	-0.6	-1.7	-0.7	-0.8	-0.5	-0.9	0.1	-0.3
Alcohol intake versus 10 years previously	0.2	0.3	1.1	-0.2	-0.7	0.0	-1.0	0.5	-0.7	0.1	-0.8	-0.3	-0.4	-0.2	-0.2
Asthma	0.2	0.4	0.8	0.7	0.9	0.8	0.5	0.3	0.9	0.2	0.8	0.5	0.3	-0.0	0.9
Arm fat mass (right)	0.2	1.0	2.1	-0.6	-0.8	-1.5	-0.9	-0.9	-1.3	-1.3	-1.0	-0.8	-1.2	-0.4	-0.9
Standing height	0.2	2.1	8.4	-0.6	1.3	-2.5	1.0	0.3	-1.1	0.3	2.9	0.4	0.2	2.4	-0.3
Tense / ‘highly strung’	0.2	0.3	1.6	-0.4	-0.4	-0.7	-1.3	0.4	-0.6	0.3	0.3	0.1	-0.1	-0.4	-0.3
Birth weight of first child	0.2	0.5	1.1	0.1	0.8	-0.9	0.3	-0.6	-0.1	-0.3	0.9	1.0	-0.7	1.1	-0.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.1	0.1	0.1	0.8	0.6	-0.4	0.7	0.3	1.1	-0.2	0.7	0.5	0.8
Arm fat-free mass (right)	0.2	1.1	4.7	-0.5	0.5	-2.0	0.4	0.5	-1.2	0.3	1.5	-0.2	-0.2	2.2	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.0	0.5	1.0	0.2	-0.3	-0.6	0.5	-0.5	0.4	0.7	-0.1	-0.7	-0.2
Pulse wave peak to peak time	0.2	0.3	1.2	-0.0	0.4	0.3	0.2	0.3	-0.4	0.3	0.9	0.6	0.0	0.4	1.1
Migraine (self-reported)	0.2	0.2	0.7	-0.5	0.3	0.4	0.6	0.1	0.4	0.0	0.9	0.0	0.8	0.0	0.6
Medication: Allopurinol	0.2	0.3	0.9	-0.0	-0.0	1.0	0.3	-0.1	0.8	0.1	-0.4	0.5	0.7	0.3	0.9
Medication: Seretide 50 evohaler	0.2	0.3	0.8	0.4	0.7	-0.1	0.2	0.8	0.2	0.6	0.8	-0.9	0.1	-0.5	-0.1
Heart disease (mother)	0.2	0.2	0.6	0.7	0.6	0.1	0.6	0.5	0.1	0.1	0.0	0.3	-0.5	0.3	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.4	-1.2	-0.2	-0.7	-0.2	-0.4	-0.5	-0.7	0.0	-0.7	-0.3	0.3	-0.1
Whole body fat mass	0.2	0.6	1.6	-0.5	-0.5	-0.9	-0.5	-1.2	-0.7	-1.3	-1.0	-0.6	-0.4	-0.7	-0.7
Alcohol intake frequency.	0.2	0.4	1.5	0.3	0.7	-0.9	-0.2	0.3	-0.3	-0.0	1.2	1.0	-0.2	-0.4	-0.1
Medication: Aspirin	0.2	0.3	1.1	0.6	0.1	0.5	0.8	-0.5	1.1	0.1	-0.0	1.0	0.2	0.3	-0.2
Illnesses of siblings: Diabetes	0.2	0.2	0.6	-0.3	0.3	0.5	0.1	-0.7	0.4	-0.5	0.5	0.3	0.6	-0.2	0.6
Loneliness, isolation	0.2	0.3	1.3	-0.4	0.4	-0.0	0.7	-1.1	-0.4	-0.9	0.1	0.5	-0.6	-0.0	-0.3
Long-standing illness, disability or infirmity	0.2	0.4	1.5	0.4	-0.2	0.4	0.5	-0.1	-0.5	0.0	-0.4	-0.6	-1.2	-1.1	-0.4
Qualifications: nursing, teaching	0.2	0.3	1.4	-0.2	-0.3	-0.5	-0.2	-0.4	-0.3	-0.7	-0.3	-0.7	-1.2	-0.6	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	1.4	-0.4	-0.3	-1.2	-0.8	0.8	-0.5	0.4	0.6	-0.5	-0.4	0.0	-0.6
Mineral and other dietary supplements	0.2	0.3	0.7	0.2	-0.3	0.7	-0.6	0.8	-0.1	0.5	0.1	0.1	0.5	-0.8	0.6
Asthma (self-reported)	0.2	0.4	0.8	0.8	0.8	0.8	0.4	0.4	0.7	0.3	0.8	0.5	0.2	-0.0	0.9
Miserableness	0.2	0.3	1.1	0.3	-0.1	0.2	0.4	0.6	0.6	0.8	1.0	0.7	0.6	0.4	0.6
High cholesterol (Self-reported)	0.2	0.4	0.7	0.1	0.6	0.8	0.8	-0.8	0.7	-0.3	-0.0	0.5	0.6	0.7	0.6
Medication: Atorvastatin	0.2	0.3	0.8	-0.8	-0.5	0.0	-0.4	-0.9	-0.0	-0.4	0.5	0.5	-0.7	-0.2	0.3
Number of operations (self-reported)	0.2	0.3	0.7	0.8	-0.1	-0.4	0.4	0.3	0.3	0.6	-0.1	-0.1	0.7	-0.8	-0.7
Commuting to job workplace: Cycle	0.2	0.3	0.7	-0.5	-0.5	0.3	-0.8	-0.1	-0.8	-0.4	-0.6	-0.7	-0.3	0.6	0.4
Myopia	0.2	0.3	1.0	-0.6	0.3	-0.1	0.3	-0.1	0.5	-0.5	0.9	-0.4	1.0	-0.2	0.1
Cholesterol lowering medication	0.2	0.3	1.1	-1.1	-0.4	-0.5	-0.3	-0.7	-0.2	-0.7	-0.2	-0.5	0.1	0.7	-0.3
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.7	-0.7	-0.9	-0.6	-0.6	-0.2	-0.7	-0.5	-0.6	-0.3	-0.4	0.5	0.0
Heart disease (siblings)	0.2	0.2	0.8	0.7	0.9	0.4	0.1	0.0	0.1	-0.1	0.1	0.7	0.1	-0.5	0.5
Impedance of whole body	0.2	0.9	3.7	0.0	0.3	1.3	0.3	-1.1	1.4	-0.7	0.1	0.4	1.4	-1.9	0.0
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.4	-1.2	-0.3	0.0	0.2	-1.1	-0.6	-0.5	-0.8	-0.6	-0.5	-0.1	-0.6
Neuroticism (Nagel 2018)	0.1	0.3	0.6	-0.5	-0.2	-0.2	-0.6	-0.4	-0.8	-0.7	0.3	-0.3	-0.5	-0.8	0.1
Alzheimer’s Disease (including proxy)	0.1	0.1	0.3	-0.2	0.1	-0.2	-0.4	-0.5	-0.5	-0.4	-0.2	0.3	-0.3	-0.5	-0.1
Fasting Glucose	0.1	0.1	0.5	-0.2	-0.2	-0.6	-0.3	0.7	-0.0	0.4	0.0	-0.1	0.4	0.4	0.3
Type 2 Diabetes (T2D) (2018)	0.1	0.3	0.7	0.5	-0.5	0.9	0.4	0.1	0.4	0.3	-0.5	0.0	-0.5	0.8	0.2
Neuroticism	0.1	0.2	0.6	-0.1	0.4	0.0	-0.4	-0.4	-0.5	-0.3	0.6	0.2	0.3	-0.8	-0.0
Hair Pigment	0.1	2.4	4.8	-2.0	-1.2	-0.3	-0.7	-2.2	-0.8	-1.8	-1.4	-1.0	-2.1	-1.6	-2.0
Number of treatments/medications taken	0.1	0.2	1.0	1.0	0.3	0.3	0.6	0.2	0.6	0.3	0.6	0.1	-0.5	-0.5	-0.4
Body mass index (BMI)	0.1	0.5	1.6	-0.2	-0.7	-0.7	-0.7	-0.5	-0.8	-0.8	-1.3	-0.7	-0.8	-0.3	-0.5
Trunk fat mass	0.1	0.5	1.7	-0.5	-0.4	-0.7	-0.3	-1.3	-0.4	-1.3	-0.8	-0.5	-0.1	-0.8	-0.6
Waist circumference	0.1	0.3	2.1	0.1	0.0	0.1	0.5	-1.5	-0.2	-1.0	-0.6	0.1	-0.3	0.2	-0.3
Qualifications: None of the above	0.1	0.2	1.6	0.2	-0.5	0.1	-0.4	0.7	-0.2	0.4	-1.2	-0.1	0.3	-0.3	-0.2
Weight	0.1	0.6	3.2	-0.4	-0.0	-1.8	-0.2	-0.3	-1.2	-0.6	0.2	-0.4	-0.7	0.8	-0.6
Impedance of arm (right)	0.1	0.7	3.4	-0.2	-0.0	0.8	-0.1	-1.4	0.4	-1.2	-0.3	0.2	0.0	-1.9	-0.5
Depression (self-reported)	0.1	0.1	0.3	-0.1	-0.4	-0.0	0.5	-0.2	0.2	0.0	-0.0	0.6	-0.0	-0.5	-0.2
Hair/balding pattern: Pattern 4	0.1	0.2	0.6	-0.6	-0.1	0.4	0.5	-0.3	-0.3	-0.5	-0.1	-0.5	-0.5	0.8	0.4
Headache pain in last month	0.1	0.1	0.6	0.2	0.4	0.3	-0.1	0.4	0.0	0.4	0.8	0.2	-0.5	0.4	0.0
Medication: Amlodipine	0.1	0.1	0.5	0.3	0.1	-0.5	-0.4	0.5	-0.2	-0.4	-0.7	-0.1	-0.5	0.3	0.1
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.9	0.0	0.6	-0.0	0.2	-0.3	0.4	-0.4	0.9	-0.0	0.0	-0.1	0.4
Leg fat percentage (right)	0.1	0.5	2.0	-0.0	-0.7	0.4	-0.4	-0.9	0.0	-0.9	-1.4	-0.4	0.1	-1.3	0.0
Wheeze or whistling in the chest in last year	0.1	0.2	1.1	-0.2	-0.3	-0.2	0.2	-0.3	0.1	-0.5	-0.7	-0.3	-0.5	-1.1	-0.2
Qualifications: College or University degree	0.1	0.5	1.6	0.1	0.5	0.5	1.2	-1.2	0.4	-1.0	-0.2	-0.6	-0.5	0.4	-0.2
Leg fat mass (right)	0.1	0.4	1.1	-0.3	-0.4	-0.6	-0.3	-1.0	-0.5	-1.0	-1.0	-0.5	-0.4	-0.5	-0.4
Comparative height size at age 10	0.1	0.8	3.4	-0.9	-0.8	-1.8	-1.0	-0.2	-1.4	-0.3	0.1	-0.2	-0.2	0.7	-1.1
Chest pain or discomfort	0.1	0.2	0.5	-0.3	-0.7	-0.4	-0.0	0.1	-0.3	0.5	0.3	-0.0	-0.4	0.7	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.7	-0.5	-0.5	0.1	-0.3	-0.8	0.1	-0.7	0.5	0.3	-0.0	-0.2	-0.1
Mood swings	0.1	0.2	0.6	0.8	-0.0	0.7	0.3	0.4	0.4	0.7	0.3	0.8	0.1	-0.0	0.2
Friendships satisfaction	0.1	0.2	0.8	-0.1	-0.2	-0.0	-0.7	0.5	0.2	0.5	0.4	0.2	0.9	-0.2	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.5	0.0	-0.2	0.7	0.1	-0.3	-0.1	0.6	0.4	0.5	0.3	0.3	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.2	-0.4	0.2	0.0	-0.4	-0.2	-0.7	0.3	0.1	0.0	-0.1	1.1	0.5
Wears glasses or contact lenses	0.1	0.1	0.3	0.3	-0.1	0.1	0.0	0.5	0.1	0.3	-0.4	0.5	-0.0	0.6	0.2
Leg fat percentage (left)	0.1	0.4	1.4	0.1	-0.4	0.5	-0.2	-1.0	0.4	-0.9	-1.2	-0.2	0.3	-1.0	0.2
Irritability	0.1	0.1	0.5	0.2	-0.4	0.2	-0.7	0.3	-0.0	0.3	0.1	0.2	0.3	-0.3	0.5
Leg fat mass (left)	0.1	0.3	0.9	-0.2	-0.3	-0.5	-0.2	-1.0	-0.3	-0.9	-0.9	-0.4	-0.1	-0.3	-0.3
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lung FVC	0.0	0.2	0.8	-0.1	0.1	0.2	-0.5	-0.4	-0.7	0.2	0.3	0.7	-0.9	0.4	0.7

Hub : Genes

C6orf97

Models

Trait associations