Best TWAS P=1.48e-12 · Best GWAS P=5.55e-13 conditioned to 0.0662
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SGCE | 0.04 | 0.00 | bslmm | 320 | 0.00 | 1.7e-01 | -6.9 | -5.3 | 1.5e-07 | 0.57 | 0.02 | 0.32 | FALSE |
| 2 | GTEx | Esophagus Muscularis | SGCE | 0.16 | 0.08 | lasso | 3 | 0.05 | 7.9e-04 | -7.0 | -7.0 | 1.9e-12 | 0.91 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Lung | SGCE | 0.16 | 0.08 | lasso | 3 | 0.09 | 3.7e-07 | -5.8 | -6.5 | 7.9e-11 | 0.87 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Nerve Tibial | SGCE | 0.24 | 0.22 | lasso | 5 | 0.21 | 5.2e-15 | -7.0 | -7.1 | 1.5e-12 | 0.91 | 0.01 | 0.99 | TRUE |
| 5 | YFS | Blood | SGCE | 0.03 | 0.01 | blup | 308 | 0.02 | 3.3e-07 | 2.7 | -5.9 | 4.9e-09 | 0.74 | 0.13 | 0.87 | FALSE |