Best TWAS P=8.58e-08 · Best GWAS P=1.17e-11 conditioned to 9.2e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | AC093668.2 | 0.25 | 0.21 | lasso | 5 | 0.18 | 1.5e-09 | -4.5 | -5.3 | 1.4e-07 | -0.16 | 0.07 | 0.91 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | RASA4 | 0.11 | 0.06 | lasso | 2 | 0.05 | 8.9e-04 | -4.8 | 5.1 | 3.0e-07 | 0.06 | 0.02 | 0.90 | TRUE |
| 3 | GTEx | Testis | POLR2J | 0.09 | 0.09 | lasso | 4 | 0.09 | 9.4e-05 | -4.5 | -5.1 | 3.0e-07 | -0.13 | 0.07 | 0.71 | TRUE |
| 4 | GTEx | Whole Blood | POLR2J | 0.05 | 0.05 | enet | 10 | 0.04 | 2.2e-04 | -4.5 | 5.4 | 8.6e-08 | 0.16 | 0.07 | 0.74 | TRUE |