Best TWAS P=1e-12 · Best GWAS P=1.75e-19 conditioned to 2.61e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 0.0008 | -8.3 | 7.1 | 1.0e-12 | -0.83 | 0.07 | 0.92 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 0.0614 | -5.6 | -5.9 | 3.7e-09 | 0.86 | 0.29 | 0.41 | FALSE |
| 3 | GTEx | Spleen | MLLT10 | 0.16 | 0.02 | lasso | 7 | 0.02 | 0.1030 | -5.6 | 6.5 | 6.2e-11 | -0.78 | 0.05 | 0.29 | FALSE |
| 4 | YFS | Blood | MLLT10 | 0.02 | 0.01 | bslmm | 298 | 0.01 | 0.0021 | -3.7 | 5.1 | 2.8e-07 | -0.38 | 0.09 | 0.03 | FALSE |