Best TWAS P=3.53e-10 · Best GWAS P=3.87e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | CBX8 | 0.21 | 0.10 | lasso | 3 | 0.08 | 1.4e-06 | 6.3 | -6.3 | 3.5e-10 | -0.99 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Lung | CBX8 | 0.28 | 0.19 | enet | 24 | 0.18 | 1.4e-13 | 6.0 | -6.1 | 8.9e-10 | -0.94 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Nerve Tibial | CBX8 | 0.16 | 0.14 | lasso | 4 | 0.14 | 5.3e-10 | 6.2 | -6.0 | 1.7e-09 | -0.99 | 0.00 | 1.00 | FALSE |