Best TWAS P=5.85e-11 · Best GWAS P=1.11e-08 conditioned to 1.8e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | IER2 | 0.08 | 0.00 | enet | 12 | 0.00 | 0.4570 | -4.2 | -6.5 | 5.9e-11 | 0.10 | 0.00 | 0.99 | TRUE |
| 2 | GTEx | Muscle Skeletal | CTC-250I14.6 | 0.10 | 0.00 | enet | 12 | 0.00 | 0.1630 | -4.2 | -6.5 | 8.1e-11 | 0.12 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Testis | CTC-425F1.4 | 0.14 | 0.03 | enet | 9 | 0.05 | 0.0020 | -4.5 | 5.5 | 4.2e-08 | -0.06 | 0.15 | 0.24 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DAND5 | 0.03 | 0.01 | blup | 31 | 0.01 | 0.0017 | -2.7 | 5.3 | 9.5e-08 | -0.06 | 0.01 | 0.04 | FALSE |