[Hub]/) : Traits : Breast Cancer : ← →

chr19:16,699,813-20,451,172

Best TWAS P=2.79e-28 · Best GWAS P=2.8e-28 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	GATAD2A	0.13	0.30	lasso	7	0.29	2.4e-35	-6.76	6.6	3.3e-11	-0.01	0.02	0.98	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MAU2	0.09	0.08	blup	369	0.10	1.0e-12	-6.07	6.4	1.5e-10	-0.02	0.16	0.84	FALSE
3	GTEx	Artery Coronary	KLHL26	0.24	0.05	enet	20	0.10	2.1e-04	7.62	-5.8	9.0e-09	-0.50	0.05	0.69	FALSE
4	GTEx	Artery Tibial	SSBP4	0.09	0.04	lasso	5	0.00	3.0e-01	10.88	-10.9	1.2e-27	-0.99	0.01	0.98	FALSE
5	GTEx	Brain Cerebellum	SUGP2	0.15	-0.01	enet	27	0.00	2.3e-01	-5.80	-7.9	2.2e-15	-0.25	0.08	0.11	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	ELL	0.17	0.00	lasso	5	0.01	2.1e-01	11.03	-10.8	2.8e-27	-0.99	0.02	0.87	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	LRRC25	0.21	-0.01	enet	25	0.00	2.2e-01	-0.49	-6.9	5.7e-12	-0.50	0.03	0.53	FALSE
8	GTEx	Cells Transformed fibroblasts	SSBP4	0.09	0.07	lasso	2	0.06	5.5e-05	10.98	-11.0	2.8e-28	-0.99	0.01	0.99	TRUE
9	GTEx	Cells Transformed fibroblasts	GATAD2A	0.07	0.00	lasso	4	0.00	8.1e-01	-6.63	-5.2	2.4e-07	0.05	0.04	0.59	FALSE
10	GTEx	Colon Transverse	CRLF1	0.18	-0.01	lasso	5	0.00	6.1e-01	2.44	5.5	3.2e-08	0.32	0.04	0.42	FALSE
11	GTEx	Esophagus Mucosa	SSBP4	0.14	0.10	lasso	2	0.14	1.3e-09	11.03	-10.6	2.9e-26	-0.97	0.01	0.99	FALSE
12	GTEx	Esophagus Muscularis	SSBP4	0.09	0.09	lasso	4	0.07	5.3e-05	6.30	-7.8	8.4e-15	-0.65	0.10	0.90	FALSE
13	GTEx	Liver	SSBP4	0.26	0.04	lasso	4	0.06	1.0e-02	7.85	-9.6	9.5e-22	-0.86	0.03	0.78	FALSE
14	GTEx	Muscle Skeletal	SUGP1	0.11	0.06	lasso	7	0.07	9.5e-08	-3.93	5.2	2.3e-07	0.02	0.50	0.49	FALSE
15	GTEx	Muscle Skeletal	MAU2	0.09	0.04	lasso	4	0.05	5.1e-06	-3.40	5.4	6.7e-08	-0.05	0.05	0.95	FALSE
16	GTEx	Muscle Skeletal	SSBP4	0.09	0.07	lasso	3	0.07	1.3e-07	10.88	-10.5	1.2e-25	-0.96	0.01	0.99	FALSE
17	GTEx	Nerve Tibial	ANKLE1	0.16	0.16	lasso	3	0.15	4.5e-11	-5.29	-5.3	1.3e-07	-0.04	0.01	0.99	TRUE
18	GTEx	Pancreas	SSBP4	0.15	-0.01	lasso	5	0.02	3.1e-02	6.30	-6.5	8.8e-11	-0.60	0.04	0.47	FALSE
19	GTEx	Skin Sun Exposed Lower leg	SSBP4	0.12	0.12	lasso	3	0.11	2.9e-09	11.03	-11.0	3.4e-28	-1.00	0.01	0.99	FALSE
20	GTEx	Spleen	ATP13A1	0.16	0.01	lasso	5	0.02	9.7e-02	-6.60	-6.6	3.9e-11	0.03	0.05	0.46	FALSE
21	GTEx	Spleen	LRRC25	0.29	-0.01	enet	48	0.00	3.4e-01	10.74	-5.4	6.5e-08	-0.57	0.04	0.47	FALSE
22	GTEx	Thyroid	SSBP4	0.09	0.11	lasso	6	0.10	8.2e-08	10.71	-10.7	7.7e-27	-0.98	0.02	0.98	FALSE
23	GTEx	Whole Blood	TMEM161A	0.06	0.00	enet	2	0.00	1.4e-01	-6.63	6.6	3.5e-11	-0.02	0.03	0.84	FALSE
24	GTEx	Whole Blood	ELL	0.10	0.03	enet	17	0.04	1.2e-04	10.71	8.8	1.8e-18	0.84	0.02	0.98	FALSE
25	GTEx	Whole Blood	GATAD2A	0.06	0.02	lasso	9	0.03	1.7e-03	-6.72	-5.9	4.3e-09	0.04	0.04	0.95	FALSE
26	GTEx	Whole Blood	LRRC25	0.12	0.01	enet	7	0.02	1.0e-02	10.98	-10.4	3.3e-25	-0.89	0.01	0.98	FALSE
27	METSIM	Adipose	ELL	0.08	0.05	lasso	7	0.06	7.1e-09	10.72	10.4	1.9e-25	0.93	0.02	0.98	FALSE
28	METSIM	Adipose	LRRC25	0.04	0.01	bslmm	385	0.01	2.8e-02	7.78	-7.0	2.2e-12	-0.59	0.05	0.64	FALSE
29	NTR	Blood	GATAD2A	0.02	0.02	blup	386	0.02	1.4e-07	-6.02	-5.7	1.2e-08	0.02	0.03	0.97	FALSE
30	NTR	Blood	LRRC25	0.03	0.01	lasso	4	0.01	2.9e-04	7.78	-7.4	1.5e-13	-0.65	0.11	0.76	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	ELL	0.27	0.39	lasso	7	0.39	4.0e-53	10.67	-10.7	1.0e-26	-0.97	0.06	0.94	FALSE
32	ROSMAP	Brain Pre-frontal Cortex	LRRC25	0.09	0.02	blup	383	0.07	7.4e-09	1.31	-6.3	2.3e-10	-0.61	0.02	0.98	FALSE
33	YFS	Blood	ELL	0.23	0.41	enet	24	0.43	2.6e-158	11.03	10.4	3.1e-25	0.96	0.01	0.99	FALSE
34	YFS	Blood	GATAD2A	0.09	0.14	blup	365	0.14	7.5e-44	-6.50	-6.8	9.9e-12	0.03	0.03	0.97	TRUE
35	YFS	Blood	LRRC25	0.35	0.19	enet	24	0.32	9.5e-108	7.78	-6.2	6.5e-10	-0.58	1.00	0.00	FALSE
36	The Cancer Genome Atlas	Breast Invasive Carcinoma	LRRC25	0.06	0.07	enet	13	0.06	5.9e-13	7.62	-8.8	1.2e-18	-0.71	1.00	0.00	FALSE
37	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	LRRC25	0.14	0.07	enet	5	0.10	8.3e-06	7.78	-7.9	2.8e-15	-0.61	0.12	0.31	FALSE
38	The Cancer Genome Atlas	Colon Adenocarcinoma	GATAD2A	0.04	0.03	blup	61	0.05	1.3e-03	-6.76	-6.2	7.0e-10	-0.01	0.02	0.87	FALSE
39	The Cancer Genome Atlas	Colon Adenocarcinoma	HAPLN4	0.10	0.08	blup	38	0.11	8.5e-07	-6.06	-5.6	2.0e-08	-0.01	0.01	0.99	FALSE
40	The Cancer Genome Atlas	Colon Adenocarcinoma	ISYNA1	0.08	0.09	lasso	4	0.09	7.0e-06	7.83	7.9	2.5e-15	0.71	0.52	0.31	FALSE
41	The Cancer Genome Atlas	Colon Adenocarcinoma	LRRC25	0.06	0.05	blup	44	0.04	1.5e-03	10.88	-9.6	6.6e-22	-0.91	0.01	0.92	FALSE
42	The Cancer Genome Atlas	Colon Adenocarcinoma	SSBP4	0.08	0.05	enet	9	0.07	6.7e-05	10.74	-9.0	1.6e-19	-0.84	0.02	0.92	FALSE
43	The Cancer Genome Atlas	Glioblastoma Multiforme	ELL	0.13	0.10	blup	46	0.08	1.9e-03	10.66	-10.9	2.0e-27	-0.95	0.02	0.85	FALSE
44	The Cancer Genome Atlas	Glioblastoma Multiforme	LRRC25	0.20	0.12	lasso	3	0.12	1.2e-04	6.41	-6.2	5.1e-10	-0.43	0.02	0.29	FALSE
45	The Cancer Genome Atlas	Glioblastoma Multiforme	UBA52	0.16	0.10	lasso	4	0.07	3.9e-03	5.56	-5.3	1.4e-07	-0.42	0.02	0.15	FALSE
46	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GATAD2A	0.02	0.02	lasso	1	0.02	2.1e-03	-6.70	-6.7	2.1e-11	0.02	0.02	0.78	FALSE
47	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HAPLN4	0.07	0.05	lasso	7	0.07	2.9e-08	-4.50	-5.7	1.4e-08	-0.03	0.03	0.97	FALSE
48	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SSBP4	0.04	0.03	blup	37	0.04	1.6e-05	10.66	-10.7	7.7e-27	-0.94	0.03	0.97	FALSE
49	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HAPLN4	0.05	0.07	lasso	2	0.06	1.1e-07	-6.12	-6.0	2.1e-09	0.03	0.01	0.99	FALSE
50	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SF4	0.03	0.01	enet	7	0.02	1.1e-03	-5.86	-5.2	1.5e-07	0.05	0.03	0.89	FALSE
51	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SSBP4	0.02	0.02	blup	37	0.03	3.7e-04	11.03	-10.3	9.7e-25	-0.93	0.01	0.97	FALSE
52	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C19orf50	0.12	0.00	enet	11	0.01	6.5e-02	0.64	-6.2	4.0e-10	-0.57	0.01	0.59	FALSE
53	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LRRC25	0.10	0.08	lasso	3	0.08	2.0e-05	6.41	-7.9	3.1e-15	-0.64	0.27	0.67	FALSE
54	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SSBP4	0.06	0.07	enet	6	0.07	5.6e-05	11.03	-10.7	1.3e-26	-0.95	0.01	0.98	FALSE
55	The Cancer Genome Atlas	Brain Lower Grade Glioma	C19orf50	0.07	0.00	blup	42	0.04	5.6e-05	-1.18	-6.4	2.0e-10	-0.50	0.07	0.25	FALSE
56	The Cancer Genome Atlas	Brain Lower Grade Glioma	KIAA0892	0.03	0.01	lasso	7	0.02	6.3e-03	-6.18	6.1	8.6e-10	-0.02	0.02	0.68	FALSE
57	The Cancer Genome Atlas	Brain Lower Grade Glioma	LRRC25	0.07	0.08	blup	46	0.09	2.2e-10	7.62	-10.0	1.9e-23	-0.85	0.16	0.84	FALSE
58	The Cancer Genome Atlas	Brain Lower Grade Glioma	SSBP4	0.03	0.03	lasso	1	0.03	9.7e-05	7.62	-7.6	2.6e-14	-0.65	0.16	0.60	FALSE
59	The Cancer Genome Atlas	Brain Lower Grade Glioma	TSSK6	0.02	0.02	blup	33	0.02	1.8e-03	-6.68	-6.1	8.1e-10	0.00	0.01	0.84	FALSE
60	The Cancer Genome Atlas	Lung Adenocarcinoma	LRRC25	0.04	0.01	blup	45	0.02	6.2e-04	7.62	-10.0	2.3e-23	-0.84	0.02	0.96	FALSE
61	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LRRC25	0.06	0.02	blup	46	0.04	5.6e-05	7.78	-9.6	6.8e-22	-0.81	0.01	0.97	FALSE
62	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SSBP4	0.02	0.03	lasso	2	0.03	5.3e-04	7.89	-8.9	6.1e-19	-0.79	0.04	0.75	FALSE
63	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	GMIP	0.07	0.00	blup	43	0.02	2.3e-02	-3.85	-5.2	1.9e-07	0.04	0.01	0.65	FALSE
64	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LRRC25	0.07	0.03	blup	46	0.02	8.5e-03	7.78	-9.9	3.9e-23	-0.89	0.02	0.74	FALSE
65	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SSBP4	0.06	0.02	blup	37	0.05	4.3e-04	10.70	-9.9	3.2e-23	-0.92	0.01	0.90	FALSE
66	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LRRC25	0.12	0.03	blup	45	0.01	1.1e-01	7.62	-6.7	2.9e-11	-0.48	0.01	0.20	FALSE
67	The Cancer Genome Atlas	Prostate Adenocarcinoma	ELL	0.03	0.03	blup	47	0.01	1.2e-02	10.67	-10.4	1.9e-25	-0.95	0.02	0.90	FALSE
68	The Cancer Genome Atlas	Prostate Adenocarcinoma	GATAD2A	0.04	0.03	lasso	2	0.03	2.9e-04	-6.61	-6.3	2.9e-10	0.04	0.02	0.94	FALSE
69	The Cancer Genome Atlas	Prostate Adenocarcinoma	LRRC25	0.03	0.04	lasso	2	0.04	4.3e-05	6.41	-6.4	1.2e-10	-0.50	0.08	0.48	FALSE
70	The Cancer Genome Atlas	Prostate Adenocarcinoma	SSBP4	0.04	0.08	enet	13	0.08	8.4e-09	10.74	-10.8	2.5e-27	-0.98	0.01	0.99	FALSE
71	The Cancer Genome Atlas	Stomach Adenocarcinoma	ISYNA1	0.05	0.04	enet	11	0.05	1.4e-04	7.97	8.4	6.3e-17	0.77	0.03	0.78	FALSE
72	The Cancer Genome Atlas	Stomach Adenocarcinoma	SSBP4	0.05	0.00	blup	37	0.02	8.7e-03	7.83	-8.0	1.5e-15	-0.67	0.02	0.20	FALSE
73	The Cancer Genome Atlas	Thyroid Carcinoma	ELL	0.06	0.06	blup	46	0.09	1.2e-08	10.82	-10.4	2.5e-25	-0.91	0.03	0.97	FALSE
74	The Cancer Genome Atlas	Thyroid Carcinoma	ISYNA1	0.04	0.00	blup	34	0.02	4.8e-03	7.97	10.1	3.5e-24	0.88	0.02	0.86	FALSE
75	The Cancer Genome Atlas	Thyroid Carcinoma	KIAA0892	0.04	0.04	blup	43	0.02	4.1e-03	-6.13	5.9	3.4e-09	-0.04	0.05	0.91	FALSE
76	The Cancer Genome Atlas	Thyroid Carcinoma	LRRC25	0.05	0.08	lasso	3	0.07	5.4e-07	7.78	-8.9	7.4e-19	-0.74	0.07	0.93	FALSE