Best TWAS P=4.28e-13 · Best GWAS P=2.31e-10 conditioned to 0.00216
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ANKRD34A | 0.03 | 0.01 | blup | 110 | 0.02 | 4.9e-04 | 5.1 | -7.2 | 4.3e-13 | -0.51 | 0.17 | 0.20 | TRUE |
| 2 | GTEx | Adipose Subcutaneous | NBPF10 | 0.06 | 0.01 | lasso | 4 | 0.03 | 2.0e-03 | 4.9 | 5.4 | 5.9e-08 | 0.45 | 0.10 | 0.25 | FALSE |
| 3 | GTEx | Brain Frontal Cortex BA9 | ANKRD34A | 0.23 | 0.20 | lasso | 6 | 0.17 | 2.3e-05 | 4.9 | -5.4 | 8.0e-08 | -0.26 | 0.14 | 0.14 | FALSE |
| 4 | METSIM | Adipose | NBPF10 | 0.09 | 0.05 | enet | 10 | 0.09 | 2.5e-13 | 4.9 | 5.2 | 2.6e-07 | 0.66 | 0.05 | 0.95 | FALSE |
| 5 | YFS | Blood | LIX1L | 0.02 | 0.01 | lasso | 3 | 0.02 | 4.0e-06 | 4.9 | -5.4 | 8.2e-08 | -0.18 | 0.94 | 0.04 | FALSE |