Best TWAS P=2.37e-13 · Best GWAS P=2.53e-11 conditioned to 0.951
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PHACTR1 | 0.19 | 0.09 | enet | 25 | 0.12 | 5.7e-07 | 7.0 | -6.6 | 3.2e-11 | 0.70 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Aorta | RP1-257A7.5 | 0.11 | 0.14 | lasso | 3 | 0.13 | 1.7e-07 | 7.2 | -6.7 | 2.8e-11 | 0.63 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Coronary | RP1-257A7.5 | 0.25 | 0.07 | lasso | 5 | 0.09 | 5.5e-04 | -6.7 | -7.3 | 2.4e-13 | 0.91 | 0.00 | 0.99 | TRUE |
| 4 | GTEx | Artery Tibial | PHACTR1 | 0.21 | 0.10 | enet | 59 | 0.13 | 2.1e-10 | 7.0 | -6.0 | 1.7e-09 | 0.67 | 0.00 | 1.00 | FALSE |
| 5 | GTEx | Artery Tibial | RP1-257A7.5 | 0.16 | 0.10 | enet | 14 | 0.11 | 7.6e-09 | -5.3 | -6.8 | 1.0e-11 | 0.84 | 0.02 | 0.98 | FALSE |