Best TWAS P=4.1e-08 · Best GWAS P=3.34e-08 conditioned to 0.245
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | MRAS | 0.52 | 0.53 | lasso | 5 | 0.54 | 2.5e-34 | 5.2 | 5.2 | 1.6e-07 | 0.96 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Artery Coronary | MRAS | 0.32 | 0.10 | lasso | 4 | 0.12 | 7.4e-05 | 5.3 | 5.5 | 4.1e-08 | 0.93 | 0.01 | 0.98 | TRUE |
| 3 | GTEx | Brain Frontal Cortex BA9 | DBR1 | 0.18 | 0.10 | lasso | 5 | 0.11 | 9.7e-04 | 5.3 | 5.3 | 8.7e-08 | 0.93 | 0.02 | 0.90 | FALSE |