Hub : Genes

PHACTR1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1890	0.0580	3.4e-04	0.091	NA	0.117	NA	0.110	1.1e-05	NA	5.7e-07	NA	1.2e-06
2	GTEx	Artery Tibial	0.2075	0.0543	1.0e-06	0.100	NA	0.131	NA	0.102	3.3e-08	NA	2.1e-10	NA	2.2e-08
3	GTEx	Cells Transformed fibroblasts	0.1060	0.0410	9.8e-03	-0.004	NA	0.006	NA	-0.001	8.9e-01	NA	1.1e-01	NA	3.7e-01
4	NTR	Blood	0.0262	0.0090	2.4e-04	0.008	0.013	0.018	0.016	0.017	7.8e-04	2.6e-05	1.5e-06	5.2e-06	1.9e-06
5	ROSMAP	Brain Pre-frontal Cortex	0.0670	0.0224	3.0e-04	0.039	0.028	0.026	0.027	0.031	7.0e-06	1.3e-04	2.6e-04	1.6e-04	6.3e-05
6	YFS	Blood	0.1446	0.0216	0.0e+00	0.112	0.153	0.163	0.172	0.168	1.5e-34	1.2e-47	8.5e-51	8.0e-54	1.3e-52
7	TCGA	Brain Lower Grade Glioma	0.0998	0.0327	8.5e-06	0.012	0.046	0.049	NA	0.037	1.3e-02	5.3e-06	2.9e-06	NA	4.5e-05
8	TCGA	Prostate Adenocarcinoma	0.0456	0.0225	6.1e-03	-0.002	0.014	0.001	NA	0.000	5.3e-01	1.2e-02	2.3e-01	NA	3.4e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.9	1.5	4.9	0.2	0.4	1.0	-2.0	1.2	0.2	2.2	-0.0
Bipolar Disorder or Schizophrenia	0.7	1.8	7.0	1.0	0.9	0.6	-2.2	0.2	-0.6	2.6	0.5
Depressed Affect (Nagel 2018)	0.4	0.9	1.6	-1.2	-0.6	-1.1	0.8	0.9	0.5	-0.9	-1.3
Depression (Nagel 2018)	0.5	0.7	2.3	-0.5	-1.5	-0.1	0.1	1.5	0.7	-0.0	0.6
Intelligence (Savage-Jansen 2018)	0.5	1.5	5.8	-1.6	-2.4	0.1	-0.7	1.0	0.2	0.3	1.4
Neuroticism (Nagel 2018)	1.0	2.2	3.5	-1.9	-1.9	-1.2	1.8	1.5	1.3	-0.7	-1.4
Schizophrenia (2018)	0.4	0.9	2.0	1.1	0.9	-0.1	-1.1	-0.7	-0.9	1.4	0.6
Schizophrenia vs Biploar Disorder	2.0	2.7	9.2	0.8	0.1	-0.6	-1.3	-2.2	-2.2	-0.1	3.0
Worry (Nagel 2018)	0.6	1.3	5.1	-1.8	-1.1	-2.2	0.6	0.3	0.3	0.8	0.2
Alzheimer’s Disease (in mother)	0.4	0.4	1.6	-0.9	0.1	0.1	0.2	1.3	0.9	-0.5	-0.2
Alzheimer’s Disease (in father)	2.5	2.7	7.7	1.7	1.0	2.0	-0.9	-1.1	-1.9	2.8	0.7
Alzheimer’s Disease (including proxy)	1.4	2.0	6.0	0.2	0.4	1.2	-1.6	-1.1	-2.4	1.6	1.4
Crohns Disease (2017)	0.7	1.5	4.9	1.3	2.0	0.6	-0.7	0.3	-0.5	-2.2	-0.2
Irritable Bowel Disease (IBD)	0.5	1.2	3.8	-0.3	0.6	0.3	0.5	1.1	0.9	-1.7	-1.9
Ulcerative Colitis (UC)	0.9	1.7	7.2	-1.3	-0.4	-0.5	1.0	1.1	1.3	-0.5	-2.7
Major Depression (MDD)	1.0	1.2	4.0	-0.6	-1.5	-2.0	-0.2	0.5	-0.3	-1.7	0.2
Reaction Time	1.1	2.0	4.0	1.9	1.4	-1.2	0.1	-1.1	-1.6	-2.0	-1.4
Verbal and Numeric Reasoning (VNR)	0.4	0.9	3.8	-1.0	-1.9	-0.8	-0.0	0.6	1.2	-0.4	0.6
Breast Cancer	0.4	0.9	4.6	-0.1	-2.1	-0.8	-0.0	-0.9	-0.6	-0.8	0.5
Ovarian Cancer	1.2	1.6	5.2	-1.8	-2.3	-1.1	-0.6	1.5	0.4	0.5	-0.1
Prostate Cancer	0.9	1.2	3.0	-0.7	-1.3	-1.7	1.1	0.6	1.1	-1.3	-0.4
Age at First Birth	1.2	1.8	4.8	-0.8	-1.2	-1.5	-2.2	-0.4	-1.4	1.2	1.1
Bipolar Disorder (2011)	3.6	3.5	9.3	3.0	3.0	1.0	-0.6	-0.2	0.4	2.8	0.4
Body Mass Index (BMI) (2010)	0.9	1.3	2.9	1.4	0.2	-0.7	-0.4	-1.5	-1.3	0.6	1.7
Coronary Artery Disease (CAD)	9.7	11.5	44.0	-6.6	-6.0	-2.3	1.3	1.4	1.2	1.1	-0.5
Crohns Disease (2012)	0.5	0.7	2.1	0.2	-0.0	0.4	-1.4	1.4	-0.4	-1.2	0.2
Mean Putamen Volume	1.4	1.6	4.5	0.7	0.6	0.1	1.9	0.6	1.1	-1.4	-2.1
Fasting Glucose	0.3	0.4	1.6	-0.6	0.1	-0.6	-0.1	-0.4	-0.3	-1.2	-0.4
HbA1C	0.4	0.4	2.1	0.1	-0.2	0.5	0.6	-1.4	-0.5	0.5	-0.3
HDL Cholesterol	0.3	0.4	0.9	0.1	0.5	0.6	-0.2	0.9	0.8	1.0	-0.6
LDL Cholesterol	0.5	0.8	1.6	1.3	1.0	-1.0	0.3	-1.2	-0.8	-0.3	0.9
Lupus	0.3	0.4	1.4	0.9	1.2	-0.4	0.0	-0.4	-0.2	-0.4	-0.7
Neuroticism (2016)	0.2	0.3	0.5	0.6	0.5	0.1	0.5	0.5	0.6	0.4	0.7
Primary Biliary Cirrhosis	0.9	1.3	3.2	0.3	0.2	-0.1	1.7	1.1	1.5	0.8	-1.8
Rheumatoid Arthritis	1.2	1.6	5.3	1.6	1.6	-0.3	2.3	-0.3	0.7	-1.3	-0.5
Schizophrenia (2014)	0.9	2.0	5.9	0.8	0.1	0.7	-1.9	-0.9	-1.5	2.4	1.4
Triglycerides	1.4	2.3	9.1	0.9	1.5	-1.9	-0.3	-0.9	-1.3	-3.0	0.8
Type 2 Diabetes (T2D) (2012)	0.9	1.1	2.6	0.2	1.1	0.3	-1.6	-1.6	-1.4	0.0	-0.5
Ulcerative Colitis	1.3	1.8	4.0	-1.2	-0.9	1.0	1.0	1.7	1.8	-0.1	-2.0
Blood Eosinophil Count	0.3	2.4	7.9	-0.2	-1.3	-0.3	1.9	1.1	1.6	-2.8	-1.4
Blood Platelet Count	0.2	1.9	5.5	2.3	2.3	0.2	1.3	-1.6	-0.3	0.1	0.1
Blood Red Count	0.6	5.7	12.2	2.8	3.3	3.0	0.6	-0.1	0.1	-3.5	-2.4
Blood White Count	0.6	4.6	7.6	2.4	2.8	0.5	2.1	2.0	1.6	-2.6	-2.2
Heel T-Score	0.1	1.1	5.0	0.7	-0.1	0.2	0.0	1.1	0.1	-1.3	-2.2
BMI	0.8	4.5	11.4	2.2	2.8	-0.7	2.8	0.2	0.8	-3.4	-1.6
Height	0.1	2.6	7.5	-0.8	0.1	-2.7	0.9	1.4	1.5	-2.3	-1.6
Waist Hip Ratio (WHR)	0.3	1.4	9.0	-1.1	-0.3	-0.4	0.3	0.7	-0.2	-3.0	-0.5
Systolic Blood Pressure	1.7	8.3	34.0	5.8	4.8	1.0	1.7	0.4	1.2	-2.0	-0.1
Smoking Status	0.5	1.2	3.5	-1.9	-1.2	-1.3	-0.1	0.9	-0.4	-0.9	1.0
Allergy or Eczema	0.2	0.4	1.3	-0.2	0.2	0.2	0.9	0.7	0.7	-0.4	-1.2
Cardiovascular Disease	0.4	1.3	3.3	1.8	1.4	-0.8	1.4	0.2	0.2	-1.6	-0.5
Hypothyroidism (self reported)	0.1	0.2	0.3	0.6	0.1	0.5	-0.6	0.1	-0.5	-0.5	0.3
Respiratory disease	1.5	3.2	9.9	-1.4	-1.2	-3.1	1.8	1.1	1.0	-2.6	0.6
Type 2 Diabetes (T2D) (2018)	0.5	0.9	3.7	-0.9	-0.0	-0.3	0.4	0.3	-0.4	-1.9	-1.4
Lung FEV1/FVC ratio	0.5	2.4	8.2	-0.5	0.1	-0.7	-1.7	-2.9	-1.1	2.1	1.4
Lung FVC	0.4	2.2	5.5	-1.5	-0.9	-1.4	-0.0	2.3	1.4	0.6	-2.2
Neuroticism	1.6	3.8	10.9	-2.8	-3.3	-3.2	0.0	0.9	-0.5	-0.0	0.4
Chronotype (morning person)	1.5	3.4	11.8	2.0	-1.7	0.2	-0.3	0.1	2.5	1.5	3.4
Hair Pigment	0.0	1.4	8.2	0.8	0.1	-1.0	0.1	0.7	0.6	-2.9	0.7
Tanning	0.4	4.5	12.6	-1.5	-1.5	-2.1	-1.4	-3.5	-2.0	1.9	2.2
Hand grip strength (left)	2.4	6.4	24.3	-4.9	-3.7	-3.3	-0.3	1.0	1.0	-0.0	0.4
Number of treatments/medications taken	1.8	3.3	9.3	3.0	2.9	0.2	2.3	0.4	1.2	-0.3	-1.2
Average weekly spirits intake	1.0	1.2	5.5	0.1	2.3	-0.8	-0.5	-1.1	-1.4	-0.5	-0.3
Sensitivity / hurt feelings	0.8	1.4	3.7	-1.0	-0.9	-0.6	1.4	0.5	0.5	-1.7	-1.9
Frequency of depressed mood in last 2 weeks	2.2	3.1	9.5	-0.8	-0.8	0.8	2.2	3.1	2.4	0.4	-1.7
Hearing difficulty/problems: Yes	0.7	1.1	2.8	0.3	-0.4	1.1	-1.6	0.1	-1.1	1.7	0.8
Relative age of first facial hair	0.9	1.8	3.7	-1.6	-1.8	-1.9	1.5	0.6	0.3	-0.4	-1.3
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	6.9	-0.5	0.7	1.5	0.5	2.6	0.3	-0.8	-1.0
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.8	1.3	0.3	0.6	0.6	0.5	1.1	0.3	0.4
Ever had hysterectomy (womb removed)	0.9	1.1	3.3	-0.2	0.1	-1.0	1.3	1.6	1.8	-0.3	-0.1
Systolic blood pressure, automated reading	2.1	6.2	23.4	4.8	4.0	1.5	1.1	1.2	1.3	-1.8	-0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.7	-0.8	-0.3	-0.0	0.2	-0.4	-0.2	0.4	0.7
Angina	7.0	9.2	29.4	-5.4	-5.0	-3.4	0.8	1.9	1.0	-1.2	-0.7
Medication for hormone replacement therapy	2.0	2.2	5.6	1.0	0.0	-1.0	1.7	1.7	2.4	-0.4	-2.0
Vitamin and mineral supplements	1.7	2.3	6.5	0.0	-0.7	1.8	-2.3	-1.4	-2.5	1.1	0.2
Supplements: Zinc	1.7	1.8	7.4	1.5	0.8	-1.1	1.2	0.4	1.2	-0.1	2.7
Medication: Co-codamol	1.5	1.8	2.9	0.4	1.7	1.0	1.6	1.5	1.2	-1.3	-1.5
Medication: Metformin	0.2	0.3	1.1	-1.0	0.5	-0.4	0.1	-0.0	-0.5	0.7	-0.0
Diabetes (father)	2.4	2.9	6.5	2.4	2.5	2.2	-1.0	-0.7	-1.3	-0.2	1.8
Diabetes (mother)	0.5	0.7	1.9	0.3	0.1	-0.2	1.4	0.5	0.7	-1.2	-1.0
Severe depression (siblings)	0.6	0.7	2.1	-1.4	-0.9	-0.9	-0.2	-0.0	-0.4	1.1	0.6
Pack years adult smoking proportion	0.4	0.7	2.3	0.3	1.5	-1.3	-0.8	-0.2	-0.6	-0.3	0.5
Impedance of leg (right)	0.4	1.9	5.0	-1.6	-0.4	-0.9	-1.9	-0.9	-1.5	-0.2	2.2
Leg fat-free mass (left)	0.7	4.0	7.7	1.3	1.4	-0.8	2.7	1.7	2.8	-2.2	-2.2
Trunk fat percentage	0.9	3.4	7.2	2.5	2.6	1.1	2.1	0.0	0.5	-2.7	-1.1
Hand grip strength (right)	1.9	5.1	14.3	-3.8	-3.2	-2.7	0.2	2.1	1.8	0.8	-0.1
Townsend deprivation index at recruitment	0.8	1.1	3.4	0.3	1.0	-1.4	0.6	1.2	-0.6	-1.9	0.7
Current tobacco smoking	1.3	2.1	6.6	-2.2	-0.6	-1.5	-0.8	0.5	-1.3	-0.4	2.6
Average weekly fortified wine intake	0.3	0.4	1.7	1.3	0.5	0.7	0.1	0.1	0.3	-0.2	0.6
Maternal smoking around birth	0.7	1.0	3.1	-0.1	-0.4	-1.2	0.8	1.2	0.9	-1.8	0.4
Fed-up feelings	0.6	1.1	2.2	1.2	1.2	0.3	1.5	0.5	1.3	-0.8	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	3.7	-0.9	-1.6	-0.1	0.1	0.1	0.2	0.2	1.9
Relative age voice broke	1.0	1.6	7.4	-1.4	-1.0	-1.2	0.9	0.2	0.2	-0.0	-2.7
Taking other prescription medications	0.8	1.2	3.8	1.3	1.9	0.1	1.7	-0.7	0.3	0.6	0.4
Age when periods started (menarche)	0.9	2.1	8.5	1.3	0.9	0.4	1.1	1.6	1.1	-2.9	-0.8
Bilateral oophorectomy (both ovaries removed)	1.7	2.0	5.2	1.8	0.8	-0.3	2.0	1.1	2.3	-0.6	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	3.1	-0.4	-0.5	-1.2	0.3	1.8	1.4	-1.2	-1.4
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	5.3	-1.9	-0.9	0.1	0.9	2.3	0.6	0.1	-0.5
Qualifications: CSEs or equivalent	0.9	1.2	3.4	0.7	1.1	0.8	1.8	0.8	1.6	-0.6	-0.8
Serious illness, injury or assault to yourself	1.0	1.2	4.7	-0.9	-0.6	0.7	1.4	-0.1	0.4	-0.8	-2.2
High blood pressure	1.1	3.0	11.3	3.4	3.0	0.4	1.3	0.3	0.5	-0.7	-1.0
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.1	0.4	1.0	-0.5	0.1	0.2	0.0	-0.4	-0.8
Multivitamins +/- minerals	3.6	4.5	14.7	-0.1	0.6	-1.3	3.6	2.2	3.8	-1.1	-0.5
Stomach or abdominal pain in last month	1.6	2.0	5.7	-2.4	-2.1	0.7	1.5	0.9	1.3	0.3	-0.1
Supplements: Glucosamine	1.5	2.0	6.9	0.5	0.8	0.4	1.3	2.6	2.4	-0.1	-0.4
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.9	-0.7	-1.3	-0.9	0.3	-0.7	-0.2	-1.4	0.5
Medication: Atenolol	0.6	0.8	3.4	-1.5	-1.9	-0.5	-0.1	-0.0	0.4	-0.1	0.3
Medication: Levothyroxine sodium	0.4	0.7	1.9	0.2	0.1	0.9	-1.1	-0.9	-1.4	0.2	0.9
Sitting height	0.1	0.9	3.6	0.5	0.1	-1.2	1.2	0.7	1.9	-0.4	0.2
Chronic bronchitis/emphysema (father)	1.0	1.1	3.0	0.1	-0.2	-1.4	1.6	0.7	0.8	-1.7	-0.5
High blood pressure (mother)	2.7	3.8	16.6	3.4	4.1	1.3	-0.0	-0.9	-0.2	0.4	0.1
Body mass index (BMI)	1.1	4.6	8.4	2.9	2.4	0.4	2.9	0.9	1.6	-2.6	-2.0
Impedance of leg (left)	0.4	2.2	4.4	-1.7	-0.5	-0.4	-2.0	-1.3	-2.0	0.0	2.1
Leg predicted mass (left)	0.8	4.0	8.0	1.4	1.4	-0.8	2.7	1.7	2.8	-2.2	-2.2
Trunk fat mass	1.0	4.2	9.9	2.4	2.5	0.7	2.7	0.8	1.4	-3.1	-1.3
Waist circumference	1.2	4.5	15.3	1.8	1.5	-0.3	2.5	1.4	1.3	-3.9	-2.3
Number of incorrect matches in round	0.3	0.6	1.5	1.2	0.4	1.2	0.3	0.1	0.2	1.2	0.2
Past tobacco smoking	1.0	1.9	5.7	1.8	1.9	0.6	-0.8	-2.4	-0.9	-0.9	0.5
Alcohol usually taken with meals	2.2	3.5	7.9	2.7	2.6	2.4	0.6	-0.1	0.4	2.8	-0.1
Nervous feelings	1.1	2.0	6.0	-2.3	-1.4	-2.4	0.4	-0.1	0.1	1.0	1.0
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	3.3	-1.6	-1.4	-1.3	0.9	1.8	1.3	0.6	-1.7
Hearing difficulty/problems with background noise	0.3	0.5	0.9	0.9	-0.4	0.4	-0.7	0.6	-0.7	1.0	-0.5
Hair/balding pattern: Pattern 2	0.6	0.8	2.6	-1.6	-1.1	-0.7	-0.5	0.8	0.2	0.6	0.7
Had menopause	0.5	0.7	2.9	-0.3	-0.4	0.4	-0.3	0.5	0.5	1.7	1.2
Had other major operations	1.5	1.9	8.8	2.0	3.0	-0.3	0.2	-1.3	0.4	0.5	0.2
Forced vital capacity (FVC)	0.7	2.7	7.2	-1.3	-0.4	-1.5	0.9	2.4	2.7	-0.8	-1.7
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	3.8	-0.1	-0.4	-0.9	1.2	1.6	1.9	-0.9	-1.5
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	2.5	-0.7	-0.8	-0.3	1.4	1.6	0.9	0.6	-0.3
Qualifications: None of the above	0.7	1.5	7.5	-0.5	0.6	-0.9	-0.5	1.5	0.5	-2.7	-0.7
Financial difficulties in last 2 years	1.1	1.5	5.5	-1.2	-0.9	-0.6	2.3	0.3	1.3	-1.4	0.4
Mouth/teeth dental problems	0.4	0.6	1.6	-0.2	-0.6	0.8	0.5	-1.3	0.8	0.0	1.0
Heart attack	13.6	17.4	59.1	-7.7	-7.6	-4.0	0.6	1.6	0.7	-0.3	-1.6
Allergy	0.5	1.2	2.7	1.1	-0.0	1.6	-1.2	-1.2	-0.5	1.4	1.0
Pain all over the body in last month	0.9	0.9	3.2	-0.2	-0.4	-1.2	-1.8	0.4	-1.5	-0.1	-0.4
Diabetes (self-reported)	0.4	0.6	2.6	0.0	1.6	-0.3	-0.1	-0.9	-0.8	-0.8	-0.5
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	2.8	-0.7	0.2	-1.7	-0.3	-0.7	-1.1	0.0	-1.6
Medication: Ramipril	0.6	0.7	4.6	-0.8	-2.1	-0.3	0.3	0.3	-0.1	0.6	-0.1
Medication: Simvastatin	0.3	0.5	1.4	-0.6	-0.7	-0.5	1.2	0.5	0.2	-0.7	-0.7
Fluid intelligence score	1.1	2.2	12.6	-1.7	-3.6	-0.4	0.3	-0.1	1.4	0.5	0.2
Illnesses of siblings	1.2	1.6	4.1	1.8	0.3	0.3	-1.3	-1.9	-0.3	-0.2	2.0
Neuroticism score	0.9	1.9	4.5	-1.9	-2.1	-1.5	1.0	1.5	0.5	-0.6	-0.9
Weight	1.1	5.3	10.1	2.5	2.4	-0.2	3.2	1.2	2.3	-3.1	-1.9
Impedance of arm (right)	0.6	2.9	5.7	-0.7	0.2	1.4	-1.6	-2.1	-2.4	2.3	1.7
Arm fat percentage (right)	1.1	4.4	8.7	2.9	3.0	1.2	2.8	0.8	1.2	-2.0	-1.6
Trunk fat-free mass	0.5	3.1	8.2	0.7	0.8	-1.3	1.8	2.2	2.9	-2.0	-1.0
Hip circumference	1.0	4.3	8.2	1.9	1.9	-1.0	2.7	1.4	1.6	-2.9	-2.6
Time employed in main current job	1.2	1.4	4.7	0.1	-0.9	0.9	-2.2	-0.9	-1.4	1.1	1.0
Alcohol intake versus 10 years previously	1.1	1.6	3.8	1.5	1.1	1.3	0.4	-1.9	-0.4	-0.5	1.9
Father’s age at death	2.7	3.6	7.5	2.2	1.5	1.8	-1.4	-2.4	-1.0	1.3	2.7
Worrier / anxious feelings	0.7	1.3	3.7	-0.9	-1.9	-1.2	1.4	1.1	0.9	0.4	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.5	-0.1	0.5	1.2	-0.2	0.0	0.3	-0.1	1.2
Falls in the last year	1.0	1.4	5.6	0.7	1.0	1.4	-0.8	-0.4	-0.9	-0.3	2.4
Hair/balding pattern: Pattern 3	1.0	1.5	5.9	0.4	0.9	0.1	-2.4	-0.9	-2.0	0.7	-0.2
Number of live births	1.4	2.0	4.4	-0.4	-0.5	-0.9	1.8	1.5	1.6	-2.1	-1.6
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	4.0	-1.4	-0.6	-2.0	-0.2	1.0	1.2	-0.1	-0.9
Pulse rate	0.6	1.1	3.2	0.6	0.8	0.4	-0.6	-1.4	-1.8	-1.0	0.9
Happiness	0.3	0.3	0.8	-0.8	-0.9	0.8	-0.2	0.3	-0.5	0.1	0.0
Noisy workplace	1.0	1.3	3.3	-1.8	-0.5	-0.9	0.4	1.6	0.1	-1.6	-0.7
Qualifications: A levels/AS levels or equivalent	1.5	3.2	15.6	-0.8	-1.9	1.5	-0.5	-1.6	-0.2	4.0	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	4.5	-0.5	-0.1	-0.8	2.1	0.2	1.0	-0.3	-1.4
Mouth/teeth dental problems: Dentures	0.6	1.1	2.4	0.6	1.0	-0.6	-0.2	1.1	-1.0	-1.5	-1.6
Asthma	1.5	3.0	7.3	-1.0	-0.5	-2.7	1.8	2.1	1.8	-2.0	-0.2
Medication: Ibuprofen (e.g. Nurofen)	6.0	7.7	33.9	5.8	4.6	0.6	1.7	-0.2	1.2	-0.5	1.3
Medication: Cholesterol lowering	0.9	1.4	4.3	-2.1	-1.8	-1.7	0.0	0.5	-0.4	-0.5	-0.0
Depression (self-reported)	0.5	0.6	1.3	-0.1	0.7	-0.1	1.1	0.6	1.0	-0.7	-0.9
Medication: Lansoprazole	1.4	1.6	4.9	-1.0	-0.5	-0.6	2.2	1.3	2.0	-0.8	-0.6
Prospective memory result	1.7	2.1	11.4	-0.1	1.9	-0.5	0.7	0.5	-0.0	-3.4	-0.7
Lung cancer (father)	1.0	1.2	3.9	0.2	0.0	-0.9	-2.0	1.6	-1.0	-1.1	0.1
Illnesses of mother	0.2	0.3	0.7	0.6	-0.6	0.8	-0.3	-0.0	-0.1	0.2	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	2.8	-1.0	-0.1	-1.7	-0.9	0.9	0.9	0.2	-0.8
Pulse wave Arterial Stiffness index	3.7	4.3	12.5	3.5	2.3	1.5	2.4	0.2	1.8	-2.3	-0.4
Impedance of arm (left)	0.6	2.6	4.5	0.3	0.6	1.5	-1.3	-1.9	-2.0	2.1	2.1
Arm fat mass (right)	1.2	5.0	8.9	2.6	2.9	0.3	3.0	1.1	1.7	-2.9	-1.9
Trunk predicted mass	0.5	3.1	8.5	0.7	0.8	-1.2	1.9	2.2	2.9	-2.0	-1.0
Standing height	0.1	1.2	3.9	-0.6	0.4	-1.4	0.8	1.0	2.0	-1.1	-0.1
Length of working week for main job	0.9	1.0	3.1	-1.4	-0.6	-1.8	-1.2	0.3	-0.7	0.7	-0.5
Exposure to tobacco smoke at home	0.8	0.9	3.0	-0.5	-0.4	-1.7	0.8	-0.4	-0.3	-1.7	-0.4
Breastfed as a baby	1.0	1.3	6.6	0.4	0.9	2.6	0.4	1.4	0.7	-0.3	-0.1
Tense / ‘highly strung’	0.2	0.3	1.2	-0.5	0.2	-0.8	0.3	1.1	0.1	0.2	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.6	3.9	0.7	0.9	0.6	1.6	2.0	1.7	-0.8	-0.9
Hair/balding pattern: Pattern 4	0.9	2.2	7.6	1.3	0.1	-0.0	2.8	0.6	2.0	-1.9	-0.1
Birth weight of first child	0.4	0.8	2.2	-1.1	-1.5	-1.0	0.3	-0.3	1.1	-0.3	0.3
Peak expiratory flow (PEF)	1.2	2.9	9.3	-2.6	-1.9	-3.1	-1.0	0.8	-0.9	0.0	-0.9
Pulse wave reflection index	0.7	0.9	3.1	0.4	0.3	0.1	1.8	0.8	1.7	0.7	0.1
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.5	-0.1	0.6	-0.7	-0.2	1.2	0.4	-0.3	-0.1
Loud music exposure frequency	1.5	1.7	4.0	-0.8	-0.1	-2.0	1.3	1.0	1.1	-1.6	-1.5
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.7	0.4	-0.3	0.4	-0.1	-1.3	-0.8	1.3	0.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.6	-1.0	-0.6	-0.9	0.5	1.3	0.8	0.6	-0.2
Blood clot in the leg (DVT)	0.3	0.4	1.2	0.1	-0.2	-1.1	0.3	-0.3	-0.7	-1.1	0.2
Medication: Paracetamol	5.8	9.5	27.5	5.2	5.2	2.5	2.4	0.4	1.9	-1.7	-1.7
Headache pain in last month	8.9	15.4	62.7	7.4	7.9	0.5	1.7	-0.5	0.5	-1.3	-0.4
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	5.8	0.6	0.4	1.0	-0.5	-1.4	-0.4	2.4	0.0
Glaucoma (self-reported)	1.0	1.2	3.6	0.9	1.5	-1.9	0.4	1.0	0.6	-0.1	-1.2
Gout (self-reported)	0.9	1.2	2.4	-1.0	-0.9	-1.3	1.6	1.1	1.4	-0.3	-0.4
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.4	1.0	0.1	1.6	-1.5	-0.6	-1.4	0.3	0.5
Medication: Amlodipine	0.4	0.6	1.2	0.5	-0.8	-0.8	-0.3	-0.1	-1.1	0.8	-1.1
Medication: Ventolin 100micrograms inhaler	1.2	1.5	7.0	-1.9	0.1	-2.6	0.5	-0.5	-0.2	0.8	-0.5
Birth weight	1.5	3.2	6.3	-2.4	-1.3	-1.7	1.6	2.0	2.5	-1.3	-0.8
Chronic bronchitis/emphysema (mother)	1.5	1.7	4.5	1.3	1.2	-1.1	2.1	0.4	1.5	-1.4	-0.8
High blood pressure (siblings)	0.4	0.6	1.3	1.1	1.2	-0.3	1.0	0.0	1.0	0.1	0.0
Forced vital capacity (FVC), Best measure	0.4	1.4	3.2	-1.1	-0.6	-1.5	-0.2	1.8	1.7	-0.1	-1.1
Body fat percentage	1.0	3.9	8.6	2.6	2.7	1.1	2.2	0.4	0.6	-2.9	-1.2
Leg fat percentage (right)	1.0	3.5	12.2	2.3	2.4	0.1	1.8	0.5	0.5	-3.5	-1.1
Arm fat-free mass (right)	0.9	4.4	9.6	0.9	1.1	-1.3	2.4	2.4	3.1	-2.8	-1.6
Exposure to tobacco smoke outside home	0.8	1.0	2.1	0.9	0.8	1.4	1.4	-0.5	0.3	-0.4	-1.4
Comparative body size at age 10	0.9	2.5	14.3	0.5	0.1	0.4	-0.4	-3.8	-1.2	1.9	0.5
Number of full brothers	0.5	0.6	1.8	1.2	1.4	-0.4	-0.1	0.1	-0.9	0.9	0.0
Worry too long after embarrassment	0.7	1.2	6.6	-0.8	-2.6	0.2	0.2	1.3	0.5	0.2	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	4.1	-0.8	-0.1	-0.2	1.6	0.6	2.0	-1.8	-1.1
Wheeze or whistling in the chest in last year	0.5	0.9	1.7	-1.1	0.3	-1.0	1.3	1.1	0.7	-0.9	-0.8
Number of children fathered	1.5	1.7	6.6	-1.8	-2.6	0.0	0.5	0.4	1.0	1.3	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	3.1	-0.7	0.0	0.1	-0.7	0.4	-0.1	1.8	-0.3
Age at first live birth	1.3	2.3	5.2	-1.5	-1.1	0.3	-1.8	-1.0	-1.3	2.3	1.9
Pulse wave peak to peak time	3.3	3.9	12.1	-3.5	-2.2	-1.3	-2.3	-0.2	-1.6	2.2	0.4
Health satisfaction	1.8	2.3	4.1	1.0	1.9	1.2	1.6	1.8	1.3	-1.0	-2.0
Shortness of breath walking on level ground	0.5	0.7	2.7	0.2	0.7	-1.1	1.6	-0.1	0.2	-0.9	-0.1
Qualifications: College or University degree	1.3	4.1	12.7	-2.1	-3.6	1.0	-0.3	-0.8	0.8	3.3	1.6
Eye problems/disorders: None of the above	1.4	1.7	3.6	-1.6	-1.6	1.9	-1.4	-0.8	-0.8	0.8	0.9
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.8	0.2	0.2	-1.1	0.6	1.3	0.3	-0.7	-0.2
Emphysema/chronic bronchitis	1.6	1.8	6.2	-1.0	-1.4	-0.3	-0.6	-2.5	-1.6	0.5	1.3
Medication for pain relief, constipation, heartburn	2.9	5.0	16.5	-4.1	-4.0	-0.8	-2.1	-0.6	-0.8	0.9	0.3
Neck or shoulder pain in last month	1.4	2.0	6.2	2.4	2.5	0.9	1.5	-0.5	0.5	0.0	0.9
Medication: Blood pressure	0.3	0.5	1.5	0.8	0.2	0.0	1.0	0.3	0.7	-1.2	-0.0
Angina (self-reported)	7.2	9.5	31.5	-5.6	-5.1	-3.5	0.7	1.8	0.8	-1.3	-0.8
Migraine (self-reported)	10.4	12.9	55.3	7.4	6.3	2.1	-0.1	-1.6	-0.9	-0.3	0.9
Medication: Ibuprofen	5.2	6.2	26.6	5.2	3.9	0.6	1.8	0.7	1.5	-0.9	0.8
Medication: Allopurinol	1.3	1.7	5.2	-0.5	-0.8	0.2	1.5	2.1	2.3	-0.3	-0.7
Medication: Omeprazole	0.6	0.7	3.1	0.1	0.8	-0.2	0.3	-1.1	-1.8	0.4	-0.4
Medication: Seretide 50 evohaler	1.0	1.2	4.5	-0.5	-1.0	-0.6	0.7	-2.1	-0.8	-1.1	1.0
Mean time to correctly identify matches	1.1	2.1	4.3	2.1	1.2	-1.2	0.1	-0.6	-1.9	-1.9	-1.5
Heart disease (mother)	2.4	2.9	13.0	-3.6	-2.6	0.2	-1.1	1.3	0.2	0.4	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.5	0.5	0.1	-0.6	0.1	0.4	-0.3	-0.6	-0.7
Whole body fat mass	1.1	4.4	11.2	2.3	2.5	0.3	2.6	0.9	1.4	-3.4	-1.5
Leg fat mass (right)	1.2	4.5	13.8	1.9	2.3	-0.5	2.6	1.0	1.4	-3.7	-1.9
Arm predicted mass (right)	1.0	4.9	10.1	0.9	0.9	-1.4	2.5	2.4	3.2	-3.2	-1.8
Pulse rate, automated reading	1.6	5.2	9.2	3.0	2.6	1.5	-2.4	-1.8	-2.4	0.3	2.9
Alcohol intake frequency.	1.9	4.5	15.1	3.9	2.6	1.6	-0.0	-2.1	-1.3	-2.1	1.0
Comparative height size at age 10	0.1	0.4	1.3	0.2	0.7	-0.0	0.1	-0.9	1.0	0.2	1.1
Number of full sisters	1.3	1.5	3.1	-1.6	-1.6	-1.2	1.4	0.0	0.4	-1.8	-0.9
Suffer from ‘nerves’	0.3	0.5	1.3	-1.0	-0.5	-1.2	0.5	0.5	0.4	0.7	0.6
Overall health rating	0.8	1.8	4.8	1.9	2.2	1.9	0.3	0.6	0.0	-1.3	0.1
Chest pain or discomfort	0.2	0.3	0.8	0.2	0.9	-0.4	0.2	0.0	-0.8	0.8	-0.3
Had major operations	1.3	1.5	6.3	-2.5	-1.7	0.3	0.3	1.0	0.5	1.2	0.3
Age at last live birth	1.9	2.7	4.8	-1.3	-1.3	-1.1	-1.3	-1.9	-1.9	2.2	1.8
Family relationship satisfaction	0.6	0.8	2.8	-0.5	0.5	1.4	0.5	0.7	0.2	0.1	-1.7
Leg pain on walking	2.0	2.5	6.6	1.7	2.6	0.2	0.8	1.8	0.8	-1.8	-1.7
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	2.8	1.5	1.0	-0.3	-0.6	-0.7	-0.9	-1.7	-0.4
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.3	-1.2	0.5	-1.5	0.0	0.7	-0.9	0.5	-0.8
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	4.9	1.6	0.7	-0.0	-2.1	-0.2	-1.0	0.8	2.2
Medication: Aspirin	1.8	2.3	7.5	-2.7	-2.5	-1.0	0.2	1.5	0.1	0.1	-1.2
Supplements: Vitamin C	0.4	0.5	1.9	0.9	0.8	-1.4	-0.3	-0.1	-0.0	-0.7	0.2
Knee pain experienced in last month	1.8	2.8	11.6	3.4	3.1	0.4	0.1	-0.4	0.0	-0.8	-0.1
Hypertension (Self-reported)	0.9	2.5	10.2	3.2	2.7	0.1	1.1	-0.2	0.2	-0.4	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	6.2	0.5	1.6	-1.5	-0.7	-2.0	-2.5	0.9	0.8
Illnesses of father: Heart disease	4.7	6.5	32.6	-5.7	-3.9	0.2	0.5	1.9	0.7	0.0	-0.6
Illnesses of siblings: Diabetes	1.1	1.4	3.9	-1.2	0.3	0.7	-2.0	0.1	-1.7	0.2	-1.4
Smoking status: Previous	1.2	1.7	4.8	-0.9	-1.2	-0.1	1.2	2.2	1.5	-0.0	-1.8
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	1.5	-0.5	1.1	-0.3	0.3	-0.9	0.4	-1.2	1.1
Whole body fat-free mass	0.6	3.6	8.2	0.9	1.1	-1.1	2.3	2.0	2.9	-2.3	-1.6
Leg fat-free mass (right)	0.6	3.4	6.6	1.2	1.3	-0.6	2.5	1.5	2.6	-1.9	-2.2
Arm fat percentage (left)	1.2	4.8	10.6	3.3	2.9	1.2	2.9	0.8	1.3	-2.3	-1.3
Average weekly red wine intake	0.7	1.1	3.4	-0.9	-1.1	0.7	-0.6	1.8	0.6	1.4	0.4
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.1	-1.2	-0.8	1.0	-0.7	-1.2	-1.5	0.5	0.7
Mood swings	0.7	1.3	2.7	0.1	0.7	0.6	1.6	1.5	1.2	-0.8	-1.6
Loneliness, isolation	1.7	2.3	5.4	-2.2	-2.3	-1.0	0.2	1.3	0.0	-2.3	-0.6
Long-standing illness, disability or infirmity	0.5	0.7	1.5	0.2	1.1	-0.1	0.9	-0.4	-1.2	-1.2	-0.8
Ever had bowel cancer screening	0.2	0.2	1.0	0.4	-0.4	-0.2	-0.6	-0.3	0.2	-0.2	1.0
Diabetes diagnosed by doctor	0.2	0.4	1.0	-0.4	1.0	-0.2	-0.3	-0.7	-0.9	-0.3	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	2.0	0.4	-0.1	-1.3	1.1	-1.4	-0.6	-1.1	-0.2
Friendships satisfaction	0.6	0.7	1.7	-0.8	-1.3	0.8	0.2	1.3	0.4	-1.0	-0.3
Qualifications: nursing, teaching	0.7	1.1	3.4	-1.2	-1.8	-0.7	0.6	0.1	0.2	1.2	-1.3
Commuting to job workplace: Walk	0.9	0.9	1.8	1.3	0.7	1.3	0.7	-0.7	1.0	0.5	1.1
Eye problems/disorders: Cataract	0.9	1.1	4.3	1.7	2.1	-0.5	1.0	0.3	0.3	-0.4	0.2
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	2.6	1.6	1.6	1.2	-0.3	-1.0	-1.4	0.3	0.5
Medication for cholesterol	0.9	1.3	4.1	-2.0	-1.2	0.8	-1.4	0.6	0.0	-0.6	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.7	-0.4	-0.3	1.6	1.0	0.4	0.7	-0.0	-0.3
Back pain experienced in last month	1.4	2.0	6.4	1.2	1.3	0.3	2.5	0.4	1.3	-1.5	-1.5
Mineral and other dietary supplements	2.3	3.1	9.8	-1.6	-1.0	0.5	-1.9	-2.1	-3.1	1.7	-0.4
Breast cancer (self-reported)	1.2	1.4	3.2	1.2	0.9	0.8	1.8	-0.3	1.1	-0.8	-1.7
Asthma (self-reported)	1.6	3.2	8.5	-0.9	-0.7	-2.9	2.1	1.9	1.9	-2.0	-0.0
Osteoporosis (self-reported)	0.8	1.0	2.8	-0.3	-1.7	1.3	-0.1	-0.3	0.4	1.7	0.5
Osteoarthritis (self-reported)	3.5	4.6	9.6	2.6	2.0	3.1	1.1	2.5	2.2	-1.4	-1.1
Medication: Aspirin	1.7	2.2	6.8	-2.6	-2.5	-0.4	-0.2	1.6	-0.1	0.8	-1.1
Medication: Gliclazide	0.7	0.8	1.6	-0.3	-0.6	1.1	-1.3	-0.2	-0.7	-1.2	0.9
Illnesses of father: None of the above (group 1)	0.6	0.7	2.9	1.7	1.2	-0.7	-0.3	-0.2	0.8	0.0	0.4
Smoking status: Current	1.3	2.1	6.3	-2.2	-0.5	-1.7	-0.5	0.3	-1.3	-0.3	2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.2	5.3	-1.6	-1.7	-0.5	-1.1	2.3	1.4	0.8	-1.8
Whole body water mass	0.7	3.7	8.7	0.9	1.1	-1.1	2.3	2.1	3.0	-2.4	-1.7
Leg predicted mass (right)	0.6	3.4	6.5	1.2	1.3	-0.6	2.5	1.5	2.6	-1.9	-2.3
Arm fat mass (left)	1.3	5.2	9.8	2.7	2.7	0.5	3.1	1.2	2.0	-2.9	-1.5
Number of self-reported non-cancer illnesses	0.8	1.4	4.0	1.2	1.7	-0.5	2.0	0.7	1.1	-1.0	-0.4
Average weekly champagne plus white wine intake	1.8	2.5	12.0	-2.0	-1.4	-3.5	0.2	-0.1	0.0	-1.4	-0.3
Miserableness	0.6	1.0	2.3	-0.4	-0.7	0.9	1.5	0.8	1.4	-0.6	-1.0
Guilty feelings	1.9	2.8	8.2	-2.4	-2.9	-0.4	1.6	1.6	1.3	-0.2	-1.3
Wears glasses or contact lenses	1.9	2.2	6.2	-0.8	-1.4	0.9	1.6	2.5	1.2	-0.9	-1.7
Ever taken oral contraceptive pill	0.4	0.5	1.3	0.7	0.8	-1.1	0.7	-0.0	0.7	-0.9	-0.1
Hearing aid user	2.7	3.0	7.0	1.5	1.7	2.7	2.2	0.4	0.8	-0.0	-2.5
Mother’s age at death	1.3	1.6	4.3	-0.2	-0.5	-0.7	-0.7	-1.6	-0.9	2.1	2.0
Financial situation satisfaction	0.4	0.5	1.0	-0.9	1.0	0.4	0.6	-0.4	-1.0	0.2	-0.4
Tinnitus: Yes, now most or all of the time	0.8	0.9	3.0	1.7	-0.1	0.7	1.0	0.8	1.4	-0.2	-0.1
Commuting to job workplace: Public transport	0.4	0.4	1.9	0.5	0.3	1.4	-0.7	-0.4	-0.5	-0.3	0.3
Eye problems/disorders: Glaucoma	2.0	2.4	4.9	1.1	1.7	-1.4	1.8	1.7	1.4	-0.1	-2.2
Medication: Blood pressure	0.6	1.1	3.4	1.9	0.9	-1.3	-0.1	-0.9	-0.8	1.0	0.4
Pain type(s) experienced in last month: Hip pain	1.0	1.3	2.8	1.7	0.8	0.7	1.4	1.6	1.0	-0.9	-0.7
Supplements: Fish oil (including cod liver oil)	1.6	2.1	5.5	1.4	0.2	0.1	1.9	1.7	2.3	-1.3	-1.1
High cholesterol (Self-reported)	0.3	0.5	1.7	-0.9	-1.3	-0.4	-0.1	-0.0	-0.8	-0.8	0.2
Medication: Bendroflumethiazide	1.6	2.4	9.8	3.1	2.1	-1.0	-1.0	-0.9	-1.4	0.1	0.8
Medication: Paracetamol	4.5	7.0	15.9	3.9	4.0	1.7	2.4	0.9	2.3	-2.4	-2.0
Medication: Lisinopril	0.8	1.1	4.3	1.2	0.6	0.8	0.3	1.1	0.6	0.1	2.1
Medication: Atorvastatin	1.8	2.3	6.2	-1.0	-1.1	-1.7	-1.8	-1.4	-2.5	1.2	-0.6
Illnesses of father: High blood pressure	1.7	2.1	5.2	2.1	2.3	2.3	0.7	-0.4	-0.8	0.7	-0.4
Alcohol drinker status: Never	1.5	1.8	5.9	1.8	1.4	-1.1	-0.2	-1.2	-0.9	-2.4	0.5
Ever smoked	1.0	1.7	6.2	-2.5	-1.6	-0.9	-0.1	1.6	0.0	1.1	0.7
Basal metabolic rate	0.8	4.3	8.5	1.3	1.5	-1.0	2.6	1.9	2.9	-2.7	-1.9
Leg fat percentage (left)	0.9	3.3	10.7	2.3	2.3	0.5	1.8	0.3	0.2	-3.3	-1.1
Arm fat-free mass (left)	0.9	4.6	9.7	1.1	1.4	-1.0	2.5	2.2	3.1	-2.9	-1.8
Number of operations (self-reported)	1.2	1.8	5.8	-0.2	0.4	0.4	0.8	2.4	2.0	1.2	-1.5
Average weekly beer plus cider intake	0.2	0.4	0.8	-0.9	-0.4	-0.6	-0.8	-0.5	-0.8	0.1	-0.1
Irritability	1.4	2.4	7.7	-1.4	-1.2	-0.9	1.3	2.8	1.0	-1.7	-1.3
Risk taking	0.6	0.8	2.2	1.5	1.3	-0.3	1.4	-0.7	0.0	-0.4	-0.3
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.9	0.9	-0.0	1.4	0.2	-0.7	0.2	0.6	0.8
Fractured/broken bones in last 5 years	0.4	0.5	1.6	0.7	1.3	0.7	0.8	-0.7	0.1	-0.2	-0.5
Age started oral contraceptive pill	0.3	0.4	1.6	0.2	0.1	0.8	-0.1	0.7	0.2	1.3	-0.5
Diastolic blood pressure, automated reading	0.9	2.9	7.9	-2.3	-0.5	-0.4	1.2	2.8	2.5	-1.0	-0.5
Ever depressed for a whole week	0.8	0.9	2.5	-0.6	-0.9	-1.6	1.4	0.8	0.2	-0.2	-0.9
Unable to work because of sickness or disability	1.0	1.3	3.5	-1.6	-0.4	-0.4	1.9	0.8	1.3	-1.2	-0.6
Commuting to job workplace: Cycle	1.0	1.2	4.4	-0.7	-2.1	-0.4	1.2	0.7	1.6	0.2	0.1
Myopia	0.6	0.8	4.3	-0.9	0.4	0.4	-2.1	1.0	-0.4	0.1	0.2
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.3	-1.2	-0.6	0.5	-1.5	-0.8	-0.8	0.7	1.2
Cholesterol lowering medication	0.3	0.5	0.9	0.2	-0.3	-1.0	1.0	-0.8	-0.4	-0.4	-0.9
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	6.2	-0.2	0.8	-1.0	-0.7	-1.4	-2.5	1.0	0.2
Pain experienced in last month	3.2	5.3	15.3	-3.8	-3.9	-0.7	-3.0	-0.0	-1.1	0.8	1.3
Supplements: Calcium	0.9	1.0	3.5	1.9	0.8	0.9	0.3	-0.5	0.4	1.0	1.2
Basal cell carcinoma (self-reported)	0.6	0.7	3.5	-0.5	-0.3	-0.5	1.9	0.2	1.2	-0.1	-0.2
Heart attack/myocardial infarction (self-reported)	14.2	18.3	62.0	-7.9	-7.7	-4.2	0.6	1.8	0.8	-0.1	-1.7
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.7	0.1	-0.2	-0.9	0.5	-0.2	-0.5	-1.3	0.3
Heart disease (siblings)	5.2	6.4	20.9	-4.6	-3.3	-1.2	1.6	2.7	0.6	-0.1	-2.7
Alcohol drinker status: Previous	0.8	0.9	2.3	1.5	-0.1	1.3	-0.6	0.1	-0.6	1.5	0.8
Pack years of smoking	0.3	0.4	1.7	0.5	1.3	-0.9	-0.5	-0.0	-0.4	-0.4	0.4
Impedance of whole body	0.5	2.6	5.3	-0.5	0.1	0.7	-1.8	-2.0	-2.3	1.4	2.3
Leg fat mass (left)	1.1	4.4	12.7	1.9	2.2	-0.2	2.7	0.9	1.4	-3.6	-1.9
Arm predicted mass (left)	0.9	4.7	10.1	1.0	1.3	-1.0	2.3	2.4	3.2	-2.9	-1.9