TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Crohns Disease (2012)
:
→
chr1:66,697,368-68,152,438
Best TWAS P=4.34e-30 · Best GWAS P=1.05e-54 conditioned to 2.64e-43
66.8M
67M
67.2M
67.4M
67.6M
67.8M
68M
68.2M
0
10
20
30
40
50
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
IL23R
0.06
0.03
blup
107
0.03
7.0e-03
8.6
11.4
4.3e-30
-0.13
0.15
0.08
TRUE
1
NTR
Blood
MIER1
0.03
0.01
bslmm
573
0.01
2.7e-05
-2.8
-6.7
2.1e-11
0.25
0.88
0.01
TRUE
3
The Cancer Genome Atlas
Rectum Adenocarcinoma
IL23R
0.17
0.03
blup
108
0.15
2.3e-04
-5.1
10.2
1.6e-24
-0.11
0.08
0.05
FALSE