Best TWAS P=4.34e-30 · Best GWAS P=1.05e-54 conditioned to 2.64e-43
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | MIER1 | 0.03 | 0.01 | bslmm | 573 | 0.01 | 2.7e-05 | -2.8 | -6.7 | 2.1e-11 | 0.25 | 0.88 | 0.01 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | IL23R | 0.06 | 0.03 | blup | 107 | 0.03 | 7.0e-03 | 8.6 | 11.4 | 4.3e-30 | -0.13 | 0.15 | 0.08 | TRUE |
| 3 | The Cancer Genome Atlas | Rectum Adenocarcinoma | IL23R | 0.17 | 0.03 | blup | 108 | 0.15 | 2.3e-04 | -5.1 | 10.2 | 1.6e-24 | -0.11 | 0.08 | 0.05 | FALSE |