Hub : Traits :

Crohns Disease (2012)

766 significantly associated models · 143 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 66697368 68152438 2 2 4.3e-30 1.1e-54 2.6e-43 22 IL23R MIER1
2 1 154325302 156671469 12 2 1.3e-10 3.6e-08 2.6e-01 96 ADAM15 MSTO2P
3 2 27971195 29344127 1 1 3.3e-08 4.6e-06 6.8e-02 84 RP11-373D23.3
4 2 61007782 61523554 1 1 4.9e-08 9.8e-08 3.1e-01 96 PEX13
5 2 101981794 103767612 4 1 4.5e-10 1.5e-10 1.0e+00 100 IL1RL1
6 2 233227833 234904144 3 1 1.8e-37 3.9e-38 1.0e+00 100 ATG16L1
7 3 47911521 50800146 19 1 8.4e-15 1.1e-13 1.1e-01 95 AMT
8 5 39986432 41555158 2 2 2.3e-12 4.5e-34 2.9e-22 36 CARD6 PTGER4
9 5 95519506 97065386 3 1 1.1e-11 9.4e-12 1.0e+00 100 LNPEP
10 5 129797129 132900729 16 8 1.8e-19 1.4e-20 NaN NaN C5orf56 P4HA2 PDLIM4 RAD50 SLC22A5
11 5 140789933 142230251 1 1 2.9e-08 6.1e-08 1.2e-01 92 NDFIP1
12 5 149124105 151236214 7 2 2.0e-18 1.6e-17 1.9e-01 98 ANXA6 DCTN4
13 5 158501850 159005439 1 1 2.4e-14 9.1e-17 7.7e-04 84 IL12B
14 6 166651581 167841508 3 1 6.0e-13 7.6e-12 1.9e-01 96 AL133458.1
15 9 4415824 5811733 1 1 2.2e-08 4.5e-11 1.1e-04 66 IGHEP2
16 9 116849447 118266112 1 1 7.6e-15 2.5e-15 7.2e-03 88 TNFSF15
17 9 138558883 140031290 7 1 5.0e-19 4.4e-20 1.0e+00 100 CARD9
18 10 34607015 36198981 2 1 1.8e-09 1.1e-09 1.0e+00 100 CUL2
19 10 59780998 60293294 1 1 2.5e-07 3.4e-07 1.0e+00 100 CISD1
20 10 63870456 65264300 2 1 7.1e-13 3.4e-19 7.2e-11 47 ADO
21 12 39904158 41454590 1 1 2.7e-10 7.9e-18 5.0e-09 54 LRRK2
22 13 43756650 45157394 1 1 3.4e-08 7.3e-09 1.0e+00 100 LACC1
23 15 66662107 68183665 1 1 2.9e-10 1.1e-12 9.1e-04 78 SMAD3
24 16 27655848 29595483 20 1 2.2e-12 9.3e-10 1.4e-01 94 EIF3C
25 16 49488151 51535063 5 8 3.2e-46 3.2e-61 1.3e-86 -43 ADCY7 CYLD NKD1 NOD2
26 17 32561182 33976619 1 1 2.6e-07 9.5e-12 6.6e-11 8 CCT6B
27 17 37137299 39048774 6 1 7.4e-09 2.4e-09 4.5e-02 89 PNMT
28 17 39863901 41265776 1 1 2.6e-07 2.9e-08 2.3e-02 83 PTRF
29 18 12538482 13133577 1 1 2.4e-14 5.1e-13 3.5e-01 98 PTPN2
30 19 9829303 11275258 2 2 2.5e-09 1.7e-08 4.1e-05 47 PDE4A S1PR5
31 19 48957497 49452462 1 1 4.1e-09 4.3e-09 1.0e+00 100 FUT2
32 20 61522825 62912463 8 1 2.5e-11 7.3e-11 1.0e+00 100 ARFRP1
33 21 45398656 45902320 1 1 2.0e-09 1.4e-13 7.6e-06 63 ICOSLG
34 22 21075537 22685340 4 1 1.2e-09 1.2e-09 1.0e+00 100 CCDC116

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder or Schizophrenia 1.22 2 0 0.0 0.00 1.0e+00 FUT2 LACC1
Intelligence (Savage-Jansen 2018) 1.86 3 2 4.4 0.00 1.0e+00 AMT EIF3C LNPEP
Neuroticism (Nagel 2018) 1.28 1 0 0.0 0.00 1.0e+00 AL133458.1
Worry (Nagel 2018) 1.45 1 0 0.0 0.00 1.0e+00 MIER1
Crohns Disease (2017) 40.59 44 43 95.6 0.99 2.8e-50 ADAM15 ADCY7 ADO AL133458.1 AMT ANXA6 ARFRP1 ATG16L1 C5orf56 CARD6 CARD9 CCDC116 CISD1 CUL2 CYLD DCTN4 EIF3C FUT2 ICOSLG IGHEP2 IL12B IL1RL1 IL23R LACC1 LNPEP LRRK2 MIER1 NDFIP1 NKD1 NOD2 P4HA2 PDE4A PDLIM4 PEX13 PNMT PTGER4 PTPN2 PTRF RAD50 RP11-373D23.3 S1PR5 SLC22A5 SMAD3 TNFSF15
Irritable Bowel Disease (IBD) 27.98 44 40 88.9 0.98 5.8e-34 ADAM15 ADCY7 ADO AL133458.1 AMT ANXA6 ARFRP1 ATG16L1 C5orf56 CARD6 CARD9 CCDC116 CISD1 CUL2 CYLD DCTN4 EIF3C FUT2 ICOSLG IGHEP2 IL12B IL1RL1 IL23R LACC1 LNPEP LRRK2 MIER1 NDFIP1 NKD1 NOD2 P4HA2 PDE4A PDLIM4 PEX13 PNMT PTGER4 PTPN2 PTRF RAD50 RP11-373D23.3 S1PR5 SLC22A5 SMAD3 TNFSF15
Ulcerative Colitis (UC) 9.57 18 12 26.7 0.94 2.7e-09 ADO AMT ARFRP1 CARD9 DCTN4 EIF3C ICOSLG IGHEP2 IL12B IL23R PDE4A PEX13 PNMT PTPN2 PTRF SLC22A5 SMAD3 TNFSF15
Verbal and Numeric Reasoning (VNR) 1.51 2 2 4.4 0.00 1.0e+00 AMT EIF3C
Breast Cancer 1.90 1 1 2.2 -0.52 4.8e-01 SLC22A5
Prostate Cancer 1.30 1 1 2.2 0.00 1.0e+00 ARFRP1
Body Mass Index (BMI) (2010) 1.43 1 1 2.2 0.00 1.0e+00 EIF3C
Fasting Glucose 1.78 1 0 0.0 0.00 1.0e+00 RP11-373D23.3
HDL Cholesterol 1.71 2 2 4.4 0.00 1.0e+00 CCDC116 PNMT
LDL Cholesterol 1.38 1 1 2.2 0.00 1.0e+00 FUT2
Lupus 2.40 1 1 2.2 0.00 1.0e+00 CCDC116
Primary Biliary Cirrhosis 2.01 1 1 2.2 0.00 1.0e+00 PNMT
Rheumatoid Arthritis 2.03 2 1 2.2 0.00 1.0e+00 PNMT PTPN2
Schizophrenia (2014) 1.29 1 0 0.0 0.00 1.0e+00 LACC1
Triglycerides 2.38 1 1 2.2 0.00 1.0e+00 RP11-373D23.3
Ulcerative Colitis 8.49 13 7 15.6 0.96 1.8e-07 AMT ARFRP1 CARD9 CUL2 ICOSLG IGHEP2 IL12B IL23R LRRK2 PEX13 PNMT PTRF TNFSF15
Blood Eosinophil Count 15.17 15 14 31.1 -0.41 9.1e-02 ADO C5orf56 CARD9 CCDC116 CUL2 IGHEP2 LNPEP NDFIP1 P4HA2 PDLIM4 PTPN2 RAD50 SLC22A5 SMAD3 TNFSF15
Blood Platelet Count 3.77 16 14 31.1 -0.38 1.1e-01 ADAM15 ADO ARFRP1 ATG16L1 C5orf56 EIF3C FUT2 IGHEP2 NDFIP1 P4HA2 PDLIM4 PNMT PTGER4 RAD50 RP11-373D23.3 SLC22A5
Blood Red Count 0.92 9 6 13.3 -0.02 9.6e-01 AMT ARFRP1 EIF3C IGHEP2 NDFIP1 PNMT PTGER4 PTPN2 RP11-373D23.3
Blood White Count 6.64 18 15 33.3 -0.58 6.2e-03 ADCY7 ADO ARFRP1 C5orf56 CARD9 CCDC116 EIF3C LNPEP NDFIP1 P4HA2 PDE4A PDLIM4 PEX13 PNMT RAD50 RP11-373D23.3 S1PR5 SLC22A5
Heel T-Score 0.57 2 2 4.4 0.00 1.0e+00 AMT CCDC116
BMI 1.28 4 3 6.7 -0.20 8.0e-01 AMT ARFRP1 EIF3C MSTO2P
Height 3.12 17 15 33.3 0.57 9.4e-03 ADO ARFRP1 ATG16L1 C5orf56 CARD9 CCDC116 FUT2 IL1RL1 MIER1 NDFIP1 P4HA2 PDE4A PDLIM4 PTRF RAD50 RP11-373D23.3 SLC22A5
Waist Hip Ratio (WHR) 0.61 1 0 0.0 0.00 1.0e+00 FUT2
Systolic Blood Pressure 1.11 6 2 4.4 0.18 7.3e-01 ADO C5orf56 CCDC116 CISD1 CUL2 FUT2
Smoking Status 1.35 1 0 0.0 0.00 1.0e+00 ARFRP1
Allergy or Eczema 5.02 15 8 17.8 0.40 1.3e-01 ADAM15 ARFRP1 C5orf56 CCDC116 IGHEP2 IL1RL1 MSTO2P NDFIP1 PDLIM4 PEX13 PNMT PTGER4 RP11-373D23.3 SLC22A5 SMAD3
Cardiovascular Disease 2.23 7 4 8.9 0.11 8.2e-01 ADO ATG16L1 C5orf56 FUT2 PDLIM4 RAD50 SLC22A5
Hypothyroidism (self reported) 3.03 4 2 4.4 0.31 6.9e-01 AL133458.1 FUT2 PTPN2 PTRF
Respiratory disease 9.17 10 8 17.8 -0.37 2.1e-01 ARFRP1 C5orf56 LACC1 NDFIP1 P4HA2 PDLIM4 PNMT RAD50 SLC22A5 SMAD3
Lung FEV1/FVC ratio 2.95 8 6 13.3 0.69 1.9e-02 ADO C5orf56 FUT2 P4HA2 PDLIM4 PNMT SLC22A5 SMAD3
Lung FVC 2.68 9 6 13.3 -0.88 1.3e-04 ADCY7 ARFRP1 C5orf56 CARD9 EIF3C P4HA2 PDLIM4 PNMT SLC22A5
Chronotype (morning person) 0.99 1 0 0.0 0.00 1.0e+00 CARD9
Hair Pigment 0.20 2 1 2.2 0.00 1.0e+00 ADAM15 CUL2
Tanning 0.29 3 2 4.4 0.00 1.0e+00 ADO IL1RL1 MSTO2P
Hand grip strength (left) 2.83 4 4 8.9 0.98 6.4e-05 C5orf56 P4HA2 PDLIM4 SLC22A5
Average weekly spirits intake 1.40 2 0 0.0 0.00 1.0e+00 AMT FUT2
Relative age of first facial hair 1.12 1 0 0.0 0.00 1.0e+00 CUL2
Systolic blood pressure, automated reading 1.10 1 1 2.2 0.00 1.0e+00 ADO
Pack years adult smoking proportion 1.29 1 0 0.0 0.00 1.0e+00 EIF3C
Impedance of leg (right) 0.90 3 1 2.2 0.00 1.0e+00 CCDC116 EIF3C MSTO2P
Leg fat-free mass (left) 2.70 8 6 13.3 0.89 2.0e-04 ADO C5orf56 EIF3C MSTO2P P4HA2 PDE4A PDLIM4 SLC22A5
Trunk fat percentage 1.62 3 3 6.7 0.00 1.0e+00 AMT ARFRP1 EIF3C
Hand grip strength (right) 3.07 5 4 8.9 0.80 1.8e-02 C5orf56 EIF3C P4HA2 PDLIM4 SLC22A5
Current tobacco smoking 1.42 1 0 0.0 0.00 1.0e+00 ARFRP1
Fed-up feelings 1.63 2 0 0.0 0.00 1.0e+00 AMT EIF3C
Taking other prescription medications 2.35 1 1 2.2 0.00 1.0e+00 AL133458.1
Age when periods started (menarche) 1.37 1 0 0.0 0.00 1.0e+00 FUT2
Heel bone mineral density (BMD) T-score, automated (left) 0.73 1 0 0.0 0.00 1.0e+00 AMT
High blood pressure 2.18 6 2 4.4 -0.46 2.2e-01 ADO C5orf56 FUT2 P4HA2 PDLIM4 SLC22A5
Hayfever, allergic rhinitis or eczema 5.71 15 9 20.0 0.04 8.9e-01 ARFRP1 C5orf56 CCDC116 IGHEP2 MSTO2P NDFIP1 P4HA2 PDLIM4 PEX13 PNMT PTGER4 RAD50 RP11-373D23.3 SLC22A5 SMAD3
Medication: Levothyroxine sodium 2.93 3 1 2.2 0.00 1.0e+00 AL133458.1 PTPN2 PTRF
Sitting height 2.13 10 6 13.3 0.62 2.3e-02 ADO C5orf56 CARD9 CCDC116 DCTN4 FUT2 MIER1 P4HA2 PDLIM4 SLC22A5
Body mass index (BMI) 1.15 3 2 4.4 0.00 1.0e+00 AMT EIF3C MSTO2P
Impedance of leg (left) 1.03 4 1 2.2 -0.57 4.3e-01 CCDC116 EIF3C MSTO2P PDLIM4
Leg predicted mass (left) 2.69 8 6 13.3 0.89 2.1e-04 ADO C5orf56 EIF3C MSTO2P P4HA2 PDE4A PDLIM4 SLC22A5
Trunk fat mass 1.74 3 3 6.7 0.00 1.0e+00 AMT ARFRP1 EIF3C
Waist circumference 1.40 3 1 2.2 0.00 1.0e+00 AMT ARFRP1 EIF3C
Past tobacco smoking 1.40 1 0 0.0 0.00 1.0e+00 ADAM15
Forced vital capacity (FVC) 1.03 1 1 2.2 0.00 1.0e+00 ARFRP1
Heel bone mineral density (BMD) T-score, automated (right) 0.68 1 0 0.0 0.00 1.0e+00 AMT
Qualifications: None of the above 0.94 2 1 2.2 0.00 1.0e+00 AMT EIF3C
Mouth/teeth dental problems 1.51 1 0 0.0 0.00 1.0e+00 FUT2
Allergy 7.49 14 9 20.0 0.16 5.3e-01 ARFRP1 C5orf56 CCDC116 IGHEP2 NDFIP1 P4HA2 PDLIM4 PEX13 PNMT PTGER4 RAD50 RP11-373D23.3 SLC22A5 SMAD3
Hayfever/allergic rhinitis (self-reported) 2.67 2 1 2.2 0.00 1.0e+00 PNMT SMAD3
Medication: Simvastatin 1.31 1 1 2.2 0.00 1.0e+00 FUT2
Fluid intelligence score 1.46 2 2 4.4 0.00 1.0e+00 AMT EIF3C
Weight 2.04 8 7 15.6 0.76 6.7e-03 AMT ARFRP1 C5orf56 EIF3C P4HA2 PDE4A PDLIM4 SLC22A5
Impedance of arm (right) 0.67 2 1 2.2 0.00 1.0e+00 NDFIP1 RP11-373D23.3
Arm fat percentage (right) 1.54 4 2 4.4 -0.12 8.8e-01 AMT ARFRP1 EIF3C MSTO2P
Trunk fat-free mass 2.43 9 7 15.6 0.88 1.8e-04 ADO C5orf56 CARD9 EIF3C P4HA2 PDE4A PDLIM4 RP11-373D23.3 SLC22A5
Hip circumference 1.48 4 2 4.4 -0.45 5.5e-01 AMT ARFRP1 EIF3C PDE4A
Alcohol intake versus 10 years previously 1.30 2 0 0.0 0.00 1.0e+00 AMT FUT2
Father's age at death 2.36 1 0 0.0 0.00 1.0e+00 SLC22A5
Forced expiratory volume in 1-second (FEV1) 1.59 2 1 2.2 0.00 1.0e+00 ARFRP1 SLC22A5
Qualifications: A levels/AS levels or equivalent 1.28 1 1 2.2 0.00 1.0e+00 AMT
Mouth/teeth dental problems: Dentures 1.79 3 1 2.2 0.00 1.0e+00 FUT2 PNMT RAD50
Asthma 9.37 11 7 15.6 -0.36 2.1e-01 ARFRP1 C5orf56 CUL2 LACC1 NDFIP1 P4HA2 PDLIM4 PNMT RAD50 SLC22A5 SMAD3
Medication: Cholesterol lowering 1.62 1 1 2.2 0.00 1.0e+00 FUT2
Forced expiratory volume in 1-second (FEV1), Best measure 1.71 5 2 4.4 0.26 6.2e-01 ADO ARFRP1 ICOSLG S1PR5 SLC22A5
Impedance of arm (left) 0.61 2 1 2.2 0.00 1.0e+00 ADCY7 RP11-373D23.3
Arm fat mass (right) 1.56 4 2 4.4 -0.11 8.9e-01 AMT ARFRP1 EIF3C MSTO2P
Trunk predicted mass 2.42 9 7 15.6 0.88 1.9e-04 ADO C5orf56 CARD9 EIF3C P4HA2 PDE4A PDLIM4 RP11-373D23.3 SLC22A5
Standing height 3.22 13 6 13.3 0.73 1.2e-03 ADO C5orf56 CARD9 CCDC116 FUT2 MIER1 P4HA2 PDE4A PDLIM4 PTRF RAD50 RP11-373D23.3 SLC22A5
Seen doctor (GP) for nerves, anxiety, tension or depression 1.27 1 0 0.0 0.00 1.0e+00 MIER1
Peak expiratory flow (PEF) 1.80 1 0 0.0 0.00 1.0e+00 FUT2
Medication for cholesterol, blood pressure or diabetes 2.19 1 0 0.0 0.00 1.0e+00 FUT2
Gout (self-reported) 0.96 1 0 0.0 0.00 1.0e+00 RP11-373D23.3
Hypothyroidism/myxoedema (self-reported) 2.74 2 1 2.2 0.00 1.0e+00 AL133458.1 PTRF
Medication: Ventolin 100micrograms inhaler 3.75 3 2 4.4 0.00 1.0e+00 NDFIP1 PNMT SMAD3
Birth weight 1.84 1 0 0.0 0.00 1.0e+00 FUT2
Forced vital capacity (FVC), Best measure 1.04 1 1 2.2 0.00 1.0e+00 ARFRP1
Body fat percentage 1.56 3 3 6.7 0.00 1.0e+00 AMT ARFRP1 EIF3C
Leg fat percentage (right) 1.51 4 3 6.7 -0.88 1.2e-01 AMT ARFRP1 EIF3C LNPEP
Arm fat-free mass (right) 2.26 8 6 13.3 0.85 8.8e-04 C5orf56 CARD9 EIF3C P4HA2 PDE4A PDLIM4 RP11-373D23.3 SLC22A5
Comparative body size at age 10 1.34 2 1 2.2 0.00 1.0e+00 EIF3C FUT2
Wheeze or whistling in the chest in last year 2.90 4 3 6.7 0.36 6.4e-01 ARFRP1 PNMT SLC22A5 SMAD3
Qualifications: College or University degree 1.73 3 2 4.4 0.00 1.0e+00 AMT ARFRP1 EIF3C
Medication: Allopurinol 0.85 1 0 0.0 0.00 1.0e+00 RP11-373D23.3
Medication: Seretide 50 evohaler 4.15 5 0 0.0 -0.76 4.6e-02 C5orf56 P4HA2 PDLIM4 SLC22A5 SMAD3
Whole body fat mass 1.67 3 3 6.7 0.00 1.0e+00 AMT ARFRP1 EIF3C
Leg fat mass (right) 1.37 3 3 6.7 0.00 1.0e+00 AMT ARFRP1 EIF3C
Arm predicted mass (right) 2.24 8 6 13.3 0.85 1.0e-03 C5orf56 CARD9 EIF3C P4HA2 PDE4A PDLIM4 RP11-373D23.3 SLC22A5
Pulse rate, automated reading 1.18 1 1 2.2 0.00 1.0e+00 AMT
Alcohol intake frequency. 1.49 2 2 4.4 0.00 1.0e+00 EIF3C FUT2
Comparative height size at age 10 3.12 8 7 15.6 0.77 5.3e-03 C5orf56 CARD9 CCDC116 EIF3C FUT2 P4HA2 PDLIM4 SLC22A5
Suffer from 'nerves' 1.40 1 1 2.2 0.00 1.0e+00 EIF3C
Overall health rating 1.16 1 0 0.0 0.00 1.0e+00 AMT
Hypertension (Self-reported) 2.06 5 3 6.7 -0.29 4.8e-01 ADO C5orf56 FUT2 PDLIM4 SLC22A5
Forced expiratory volume in 1-second (FEV1), predicted 2.04 4 1 2.2 0.98 6.8e-05 P4HA2 PDE4A PDLIM4 SLC22A5
Whole body fat-free mass 2.53 9 7 15.6 0.88 1.3e-04 ADO C5orf56 CARD9 EIF3C P4HA2 PDE4A PDLIM4 RP11-373D23.3 SLC22A5
Leg fat-free mass (right) 2.60 8 6 13.3 0.89 2.3e-04 ADO C5orf56 EIF3C MSTO2P P4HA2 PDE4A PDLIM4 SLC22A5
Arm fat percentage (left) 1.54 4 2 4.4 -0.12 8.8e-01 AMT ARFRP1 EIF3C MSTO2P
Long-standing illness, disability or infirmity 2.24 1 0 0.0 0.00 1.0e+00 AL133458.1
Qualifications: nursing, teaching 0.91 1 0 0.0 0.00 1.0e+00 AMT
Mouth/teeth dental problems: Mouth ulcers 2.21 3 1 2.2 0.00 1.0e+00 IL12B PNMT TNFSF15
Medication for cholesterol 1.32 1 0 0.0 0.00 1.0e+00 FUT2
Asthma (self-reported) 9.45 11 8 17.8 -0.36 2.0e-01 ARFRP1 C5orf56 CUL2 LACC1 NDFIP1 P4HA2 PDLIM4 PNMT RAD50 SLC22A5 SMAD3
Smoking status: Current 1.33 1 0 0.0 0.00 1.0e+00 ARFRP1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.46 3 1 2.2 0.00 1.0e+00 ARFRP1 EIF3C PNMT
Whole body water mass 2.55 9 7 15.6 0.88 1.3e-04 ADO C5orf56 CARD9 EIF3C P4HA2 PDE4A PDLIM4 RP11-373D23.3 SLC22A5
Leg predicted mass (right) 2.61 9 6 13.3 0.81 1.5e-03 ADO C5orf56 EIF3C MSTO2P P4HA2 PDE4A PDLIM4 RP11-373D23.3 SLC22A5
Arm fat mass (left) 1.51 4 2 4.4 -0.51 4.9e-01 AMT ARFRP1 EIF3C PDE4A
Number of self-reported non-cancer illnesses 2.84 4 0 0.0 0.19 8.1e-01 ARFRP1 FUT2 PDLIM4 SLC22A5
Medication: Blood pressure 2.10 3 1 2.2 -0.99 1.1e-02 P4HA2 PDLIM4 SLC22A5
High cholesterol (Self-reported) 1.59 1 1 2.2 0.00 1.0e+00 FUT2
Medication: Bendroflumethiazide 2.50 4 0 0.0 -0.67 2.2e-01 FUT2 P4HA2 PDLIM4 SLC22A5
Medication: Paracetamol 1.55 1 0 0.0 0.00 1.0e+00 CYLD
Ever smoked 1.60 1 0 0.0 0.00 1.0e+00 ADAM15
Basal metabolic rate 2.47 9 6 13.3 0.89 1.3e-04 ADO C5orf56 CARD9 EIF3C P4HA2 PDE4A PDLIM4 RP11-373D23.3 SLC22A5
Leg fat percentage (left) 1.66 3 3 6.7 0.00 1.0e+00 AMT ARFRP1 EIF3C
Arm fat-free mass (left) 2.31 8 7 15.6 0.86 6.4e-04 C5orf56 CARD9 EIF3C P4HA2 PDE4A PDLIM4 RP11-373D23.3 SLC22A5
Irritability 0.84 1 0 0.0 0.00 1.0e+00 LNPEP
Diastolic blood pressure, automated reading 1.98 7 2 4.4 -0.32 4.8e-01 ADAM15 ADO AMT ARFRP1 LNPEP P4HA2 PDLIM4
Vascular/heart problems diagnosed by doctor 2.32 5 4 8.9 0.34 4.2e-01 ADO C5orf56 FUT2 PDLIM4 SLC22A5
Cholesterol lowering medication 1.26 1 0 0.0 0.00 1.0e+00 FUT2
Impedance of whole body 0.54 1 0 0.0 0.00 1.0e+00 RP11-373D23.3
Leg fat mass (left) 1.40 3 3 6.7 0.00 1.0e+00 AMT ARFRP1 EIF3C
Arm predicted mass (left) 2.36 8 7 15.6 0.86 6.1e-04 C5orf56 CARD9 EIF3C P4HA2 PDE4A PDLIM4 RP11-373D23.3 SLC22A5

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 14 0.42 1.6
GTEx Adipose Visceral Omentum 9 0.46 1.7
GTEx Adrenal Gland 7 0.50 1.7
GTEx Artery Aorta 11 0.39 1.7
GTEx Artery Coronary 8 0.71 1.8
GTEx Artery Tibial 22 0.61 1.7
GTEx Brain Caudate basal ganglia 7 0.79 1.8
GTEx Brain Cerebellar Hemisphere 8 0.56 1.8
GTEx Brain Cerebellum 8 0.42 1.8
GTEx Brain Cortex 8 0.80 1.9
GTEx Brain Frontal Cortex BA9 4 0.45 1.8
GTEx Brain Hippocampus 3 0.59 1.8
GTEx Brain Hypothalamus 4 0.71 1.9
GTEx Brain Nucleus accumbens basal ganglia 7 0.84 1.9
GTEx Brain Putamen basal ganglia 5 0.83 2.0
GTEx Breast Mammary Tissue 8 0.42 1.7
GTEx Breast Mammary Tissue (Male) 6 0.53 1.7
GTEx Breast Mammary Tissue (Female) 7 0.46 1.7
GTEx Cells EBV-transformed lymphocytes 4 0.29 1.6
GTEx Cells Transformed fibroblasts 19 0.47 1.7
GTEx Colon Sigmoid 6 0.43 1.7
GTEx Colon Transverse 9 0.46 1.8
GTEx Esophagus Gastroesophageal Junction 12 0.87 1.9
GTEx Esophagus Mucosa 24 0.75 1.9
GTEx Esophagus Muscularis 17 0.55 1.7
GTEx Heart Atrial Appendage 11 0.73 1.8
GTEx Heart Left Ventricle 6 0.41 1.8
GTEx Liver 2 0.29 1.7
GTEx Lung 20 0.73 1.8
GTEx Muscle Skeletal 12 0.43 1.6
GTEx Nerve Tibial 22 0.53 1.7
GTEx Ovary 7 0.80 1.9
GTEx Pancreas 4 0.25 1.7
GTEx Pituitary 6 0.56 1.8
GTEx Prostate 6 0.75 1.8
GTEx Skin Not Sun Exposed Suprapubic 16 0.67 1.8
GTEx Skin Sun Exposed Lower leg 19 0.55 1.7
GTEx Small Intestine Terminal Ileum 2 0.45 1.7
GTEx Spleen 8 0.59 1.8
GTEx Stomach 10 0.72 1.9
GTEx Testis 16 0.53 1.7
GTEx Thyroid 23 0.60 1.7
GTEx Uterus 2 0.37 1.7
GTEx Vagina 6 0.99 1.9
GTEx Whole Blood 16 0.84 1.9
METSIM Adipose 18 0.40 1.6
NTR Blood 18 0.76 1.9
ROSMAP Brain Pre-frontal Cortex 13 0.31 1.6
YFS Blood 21 0.47 1.7
CommonMind Brain Pre-frontal Cortex 19 0.36 1.6
The Cancer Genome Atlas Bladder Urothelial Carcinoma 7 0.46 1.6
The Cancer Genome Atlas Breast Invasive Carcinoma 17 0.41 1.6
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 6 0.59 1.7
The Cancer Genome Atlas Colon Adenocarcinoma 12 0.63 1.8
The Cancer Genome Atlas Esophageal Carcinoma 3 0.47 1.6
The Cancer Genome Atlas Glioblastoma Multiforme 3 0.32 1.7
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 13 0.51 1.7
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 18 0.47 1.6
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 9 0.47 1.7
The Cancer Genome Atlas Brain Lower Grade Glioma 21 0.52 1.6
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 4 0.39 1.7
The Cancer Genome Atlas Lung Adenocarcinoma 13 0.48 1.8
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 11 0.47 1.7
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 8 0.54 1.7
The Cancer Genome Atlas Pancreatic Adenocarcinoma 10 0.65 1.7
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 4 0.33 1.6
The Cancer Genome Atlas Prostate Adenocarcinoma 21 0.49 1.6
The Cancer Genome Atlas Rectum Adenocarcinoma 6 0.91 1.9
The Cancer Genome Atlas Soft Tissue Sarcoma 3 0.31 1.6
The Cancer Genome Atlas Skin Cutaneous Melanoma 4 0.82 1.8
The Cancer Genome Atlas Stomach Adenocarcinoma 8 0.51 1.7
The Cancer Genome Atlas Testicular Germ Cell Tumors 4 0.34 1.7
The Cancer Genome Atlas Thyroid Carcinoma 19 0.40 1.6
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 2 0.43 1.6