766 significantly associated models · 143 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 66697368 | 68152438 | 2 | 2 | 4.3e-30 | 1.1e-54 | 2.6e-43 | 22 | IL23R MIER1 |
2 | 1 | 154325302 | 156671469 | 12 | 2 | 1.3e-10 | 3.6e-08 | 2.6e-01 | 96 | ADAM15 MSTO2P |
3 | 2 | 27971195 | 29344127 | 1 | 1 | 3.3e-08 | 4.6e-06 | 6.8e-02 | 84 | RP11-373D23.3 |
4 | 2 | 61007782 | 61523554 | 1 | 1 | 4.9e-08 | 9.8e-08 | 3.1e-01 | 96 | PEX13 |
5 | 2 | 101981794 | 103767612 | 4 | 1 | 4.5e-10 | 1.5e-10 | 1.0e+00 | 100 | IL1RL1 |
6 | 2 | 233227833 | 234904144 | 3 | 1 | 1.8e-37 | 3.9e-38 | 1.0e+00 | 100 | ATG16L1 |
7 | 3 | 47911521 | 50800146 | 19 | 1 | 8.4e-15 | 1.1e-13 | 1.1e-01 | 95 | AMT |
8 | 5 | 39986432 | 41555158 | 2 | 2 | 2.3e-12 | 4.5e-34 | 2.9e-22 | 36 | CARD6 PTGER4 |
9 | 5 | 95519506 | 97065386 | 3 | 1 | 1.1e-11 | 9.4e-12 | 1.0e+00 | 100 | LNPEP |
10 | 5 | 129797129 | 132900729 | 16 | 8 | 1.8e-19 | 1.4e-20 | NaN | NaN | C5orf56 P4HA2 PDLIM4 RAD50 SLC22A5 |
11 | 5 | 140789933 | 142230251 | 1 | 1 | 2.9e-08 | 6.1e-08 | 1.2e-01 | 92 | NDFIP1 |
12 | 5 | 149124105 | 151236214 | 7 | 2 | 2.0e-18 | 1.6e-17 | 1.9e-01 | 98 | ANXA6 DCTN4 |
13 | 5 | 158501850 | 159005439 | 1 | 1 | 2.4e-14 | 9.1e-17 | 7.7e-04 | 84 | IL12B |
14 | 6 | 166651581 | 167841508 | 3 | 1 | 6.0e-13 | 7.6e-12 | 1.9e-01 | 96 | AL133458.1 |
15 | 9 | 4415824 | 5811733 | 1 | 1 | 2.2e-08 | 4.5e-11 | 1.1e-04 | 66 | IGHEP2 |
16 | 9 | 116849447 | 118266112 | 1 | 1 | 7.6e-15 | 2.5e-15 | 7.2e-03 | 88 | TNFSF15 |
17 | 9 | 138558883 | 140031290 | 7 | 1 | 5.0e-19 | 4.4e-20 | 1.0e+00 | 100 | CARD9 |
18 | 10 | 34607015 | 36198981 | 2 | 1 | 1.8e-09 | 1.1e-09 | 1.0e+00 | 100 | CUL2 |
19 | 10 | 59780998 | 60293294 | 1 | 1 | 2.5e-07 | 3.4e-07 | 1.0e+00 | 100 | CISD1 |
20 | 10 | 63870456 | 65264300 | 2 | 1 | 7.1e-13 | 3.4e-19 | 7.2e-11 | 47 | ADO |
21 | 12 | 39904158 | 41454590 | 1 | 1 | 2.7e-10 | 7.9e-18 | 5.0e-09 | 54 | LRRK2 |
22 | 13 | 43756650 | 45157394 | 1 | 1 | 3.4e-08 | 7.3e-09 | 1.0e+00 | 100 | LACC1 |
23 | 15 | 66662107 | 68183665 | 1 | 1 | 2.9e-10 | 1.1e-12 | 9.1e-04 | 78 | SMAD3 |
24 | 16 | 27655848 | 29595483 | 20 | 1 | 2.2e-12 | 9.3e-10 | 1.4e-01 | 94 | EIF3C |
25 | 16 | 49488151 | 51535063 | 5 | 8 | 3.2e-46 | 3.2e-61 | 1.3e-86 | -43 | ADCY7 CYLD NKD1 NOD2 |
26 | 17 | 32561182 | 33976619 | 1 | 1 | 2.6e-07 | 9.5e-12 | 6.6e-11 | 8 | CCT6B |
27 | 17 | 37137299 | 39048774 | 6 | 1 | 7.4e-09 | 2.4e-09 | 4.5e-02 | 89 | PNMT |
28 | 17 | 39863901 | 41265776 | 1 | 1 | 2.6e-07 | 2.9e-08 | 2.3e-02 | 83 | PTRF |
29 | 18 | 12538482 | 13133577 | 1 | 1 | 2.4e-14 | 5.1e-13 | 3.5e-01 | 98 | PTPN2 |
30 | 19 | 9829303 | 11275258 | 2 | 2 | 2.5e-09 | 1.7e-08 | 4.1e-05 | 47 | PDE4A S1PR5 |
31 | 19 | 48957497 | 49452462 | 1 | 1 | 4.1e-09 | 4.3e-09 | 1.0e+00 | 100 | FUT2 |
32 | 20 | 61522825 | 62912463 | 8 | 1 | 2.5e-11 | 7.3e-11 | 1.0e+00 | 100 | ARFRP1 |
33 | 21 | 45398656 | 45902320 | 1 | 1 | 2.0e-09 | 1.4e-13 | 7.6e-06 | 63 | ICOSLG |
34 | 22 | 21075537 | 22685340 | 4 | 1 | 1.2e-09 | 1.2e-09 | 1.0e+00 | 100 | CCDC116 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Brain Putamen basal ganglia | 5 | 0.83 | 2.0 |
GTEx | Brain Cortex | 8 | 0.80 | 1.9 |
GTEx | Brain Hypothalamus | 4 | 0.71 | 1.9 |
GTEx | Brain Nucleus accumbens basal ganglia | 7 | 0.84 | 1.9 |
GTEx | Esophagus Gastroesophageal Junction | 12 | 0.87 | 1.9 |
GTEx | Esophagus Mucosa | 24 | 0.75 | 1.9 |
GTEx | Ovary | 7 | 0.80 | 1.9 |
GTEx | Stomach | 10 | 0.72 | 1.9 |
GTEx | Vagina | 6 | 0.99 | 1.9 |
GTEx | Whole Blood | 16 | 0.84 | 1.9 |
NTR | Blood | 18 | 0.76 | 1.9 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 6 | 0.91 | 1.9 |
GTEx | Artery Coronary | 8 | 0.71 | 1.8 |
GTEx | Brain Caudate basal ganglia | 7 | 0.79 | 1.8 |
GTEx | Brain Cerebellar Hemisphere | 8 | 0.56 | 1.8 |
GTEx | Brain Cerebellum | 8 | 0.42 | 1.8 |
GTEx | Brain Frontal Cortex BA9 | 4 | 0.45 | 1.8 |
GTEx | Brain Hippocampus | 3 | 0.59 | 1.8 |
GTEx | Colon Transverse | 9 | 0.46 | 1.8 |
GTEx | Heart Atrial Appendage | 11 | 0.73 | 1.8 |
GTEx | Heart Left Ventricle | 6 | 0.41 | 1.8 |
GTEx | Lung | 20 | 0.73 | 1.8 |
GTEx | Pituitary | 6 | 0.56 | 1.8 |
GTEx | Prostate | 6 | 0.75 | 1.8 |
GTEx | Skin Not Sun Exposed Suprapubic | 16 | 0.67 | 1.8 |
GTEx | Spleen | 8 | 0.59 | 1.8 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 12 | 0.63 | 1.8 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 13 | 0.48 | 1.8 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 4 | 0.82 | 1.8 |
GTEx | Adipose Visceral Omentum | 9 | 0.46 | 1.7 |
GTEx | Adrenal Gland | 7 | 0.50 | 1.7 |
GTEx | Artery Aorta | 11 | 0.39 | 1.7 |
GTEx | Artery Tibial | 22 | 0.61 | 1.7 |
GTEx | Breast Mammary Tissue | 8 | 0.42 | 1.7 |
GTEx | Breast Mammary Tissue (Male) | 6 | 0.53 | 1.7 |
GTEx | Breast Mammary Tissue (Female) | 7 | 0.46 | 1.7 |
GTEx | Cells Transformed fibroblasts | 19 | 0.47 | 1.7 |
GTEx | Colon Sigmoid | 6 | 0.43 | 1.7 |
GTEx | Esophagus Muscularis | 17 | 0.55 | 1.7 |
GTEx | Liver | 2 | 0.29 | 1.7 |
GTEx | Nerve Tibial | 22 | 0.53 | 1.7 |
GTEx | Pancreas | 4 | 0.25 | 1.7 |
GTEx | Skin Sun Exposed Lower leg | 19 | 0.55 | 1.7 |
GTEx | Small Intestine Terminal Ileum | 2 | 0.45 | 1.7 |
GTEx | Testis | 16 | 0.53 | 1.7 |
GTEx | Thyroid | 23 | 0.60 | 1.7 |
GTEx | Uterus | 2 | 0.37 | 1.7 |
YFS | Blood | 21 | 0.47 | 1.7 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 6 | 0.59 | 1.7 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 3 | 0.32 | 1.7 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 13 | 0.51 | 1.7 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 9 | 0.47 | 1.7 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 4 | 0.39 | 1.7 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 11 | 0.47 | 1.7 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 8 | 0.54 | 1.7 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 10 | 0.65 | 1.7 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 8 | 0.51 | 1.7 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 4 | 0.34 | 1.7 |
GTEx | Adipose Subcutaneous | 14 | 0.42 | 1.6 |
GTEx | Cells EBV-transformed lymphocytes | 4 | 0.29 | 1.6 |
GTEx | Muscle Skeletal | 12 | 0.43 | 1.6 |
METSIM | Adipose | 18 | 0.40 | 1.6 |
ROSMAP | Brain Pre-frontal Cortex | 13 | 0.31 | 1.6 |
CommonMind | Brain Pre-frontal Cortex | 19 | 0.36 | 1.6 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 7 | 0.46 | 1.6 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 17 | 0.41 | 1.6 |
The Cancer Genome Atlas | Esophageal Carcinoma | 3 | 0.47 | 1.6 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 18 | 0.47 | 1.6 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 21 | 0.52 | 1.6 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 4 | 0.33 | 1.6 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 21 | 0.49 | 1.6 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 3 | 0.31 | 1.6 |
The Cancer Genome Atlas | Thyroid Carcinoma | 19 | 0.40 | 1.6 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 2 | 0.43 | 1.6 |