[Hub]/) : Traits : Crohns Disease (2012) : ← →

chr1:154,325,302-156,671,469

Best TWAS P=1.29e-10 · Best GWAS P=3.62e-08 conditioned to 0.26

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
40	The Cancer Genome Atlas	Prostate Adenocarcinoma	MSTO2P	0.04	0.00	enet	9	0.02	4.2e-03	5.0	-6.4	1.3e-10	-0.63	0.00	0.25	TRUE
28	YFS	Blood	ADAM15	0.58	0.15	bslmm	373	0.40	3.7e-144	-4.1	-5.4	8.0e-08	-0.34	0.91	0.08	TRUE
8	GTEx	Cells Transformed fibroblasts	ADAM15	0.14	0.01	lasso	6	0.02	9.3e-03	5.5	-5.9	3.4e-09	-0.80	0.04	0.94	FALSE
34	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ARHGEF2	0.07	0.00	enet	9	0.02	2.8e-03	-3.6	-5.9	3.4e-09	-0.55	0.02	0.74	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	FAM189B	0.09	0.00	enet	18	0.04	2.0e-03	5.4	-5.8	8.8e-09	-0.77	0.04	0.92	FALSE
22	GTEx	Testis	SCAMP3	0.09	0.01	lasso	5	0.02	5.1e-02	5.5	5.7	1.1e-08	0.85	0.04	0.87	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	GBAP1	0.21	0.05	lasso	3	0.06	4.5e-03	-4.2	-5.6	1.8e-08	-0.77	0.12	0.75	FALSE
23	GTEx	Thyroid	DAP3	0.11	0.04	lasso	9	0.04	8.9e-04	5.5	-5.6	2.1e-08	-0.92	0.04	0.89	FALSE
10	GTEx	Cells Transformed fibroblasts	HCN3	0.05	0.05	lasso	5	0.06	3.8e-05	5.5	-5.6	2.4e-08	-0.98	0.02	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DAP3	0.03	0.01	blup	248	0.02	1.5e-03	5.4	5.5	3.0e-08	0.87	0.06	0.89	FALSE
18	GTEx	Nerve Tibial	HCN3	0.17	0.28	lasso	6	0.25	5.8e-18	5.5	-5.5	3.7e-08	-0.97	0.01	0.99	FALSE
39	The Cancer Genome Atlas	Prostate Adenocarcinoma	FDPS	0.02	0.02	lasso	2	0.01	1.6e-02	5.5	-5.5	4.0e-08	-1.00	0.01	0.70	FALSE
9	GTEx	Cells Transformed fibroblasts	RIT1	0.15	0.18	lasso	4	0.18	2.7e-13	5.2	-5.4	5.2e-08	-0.71	0.02	0.98	FALSE
35	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GBA	0.04	0.01	blup	26	0.01	8.3e-03	5.2	-5.4	5.3e-08	-0.94	0.01	0.70	FALSE
36	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HCN3	0.03	0.03	lasso	1	0.03	2.3e-04	5.4	-5.4	5.7e-08	-0.94	0.02	0.93	FALSE
37	The Cancer Genome Atlas	Lung Adenocarcinoma	MSTO2P	0.05	0.03	lasso	3	0.03	4.9e-04	5.4	-5.4	5.9e-08	-0.75	0.00	0.98	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	MSTO2P	0.02	0.02	lasso	2	0.01	1.0e-03	5.4	-5.4	6.7e-08	-0.73	0.00	0.97	FALSE
25	GTEx	Thyroid	HCN3	0.05	0.05	lasso	1	0.04	5.2e-04	5.4	-5.4	7.2e-08	-0.99	0.02	0.92	FALSE
27	GTEx	Thyroid	MSTO2P	0.05	0.05	lasso	5	0.04	6.2e-04	5.4	-5.4	8.3e-08	-0.80	0.09	0.87	FALSE
26	GTEx	Thyroid	FAM189B	0.08	0.10	lasso	2	0.11	5.3e-09	5.1	-5.4	8.5e-08	-0.96	0.06	0.94	FALSE
33	The Cancer Genome Atlas	Breast Invasive Carcinoma	RIT1	0.02	0.01	blup	39	0.02	3.1e-04	4.9	-5.3	9.4e-08	-0.73	0.01	0.98	FALSE
17	GTEx	Nerve Tibial	RIT1	0.12	0.10	lasso	5	0.09	8.8e-07	5.0	-5.3	9.8e-08	-0.74	0.06	0.94	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FDPS	0.04	0.04	lasso	2	0.04	3.3e-05	5.4	-5.3	1.1e-07	-0.92	0.06	0.93	FALSE
12	GTEx	Esophagus Mucosa	ARHGEF2	0.09	0.01	lasso	4	0.01	8.4e-02	5.3	-5.3	1.1e-07	-0.62	0.05	0.84	FALSE
4	GTEx	Adrenal Gland	RIT1	0.24	0.03	lasso	4	0.04	1.8e-02	5.2	-5.2	1.5e-07	-0.67	0.04	0.55	FALSE
21	GTEx	Stomach	GBAP1	0.09	0.12	lasso	3	0.13	1.2e-06	-4.2	-5.3	1.5e-07	-0.81	0.07	0.92	FALSE
29	YFS	Blood	FAM189B	0.02	0.01	bslmm	312	0.02	3.2e-06	3.7	5.2	1.5e-07	0.77	0.12	0.88	FALSE
3	CommonMind	Brain Pre-frontal Cortex	GBAP1	0.04	0.03	blup	337	0.03	8.6e-05	-3.5	-5.2	1.7e-07	-0.62	0.70	0.20	FALSE
6	GTEx	Breast Mammary Tissue (Male)	FAM189B	0.21	0.00	lasso	7	-0.01	6.3e-01	5.4	-5.2	1.7e-07	-0.96	0.03	0.45	FALSE
30	YFS	Blood	SYT11	0.01	0.01	lasso	4	0.01	2.8e-05	5.1	-5.2	1.7e-07	-0.73	0.04	0.96	FALSE
38	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	GBA	0.02	0.00	blup	27	0.01	1.2e-02	5.3	-5.2	1.7e-07	-0.91	0.01	0.48	FALSE
41	The Cancer Genome Atlas	Prostate Adenocarcinoma	RIT1	0.05	0.05	lasso	4	0.04	2.2e-05	5.2	-5.2	1.7e-07	-0.71	0.01	0.99	FALSE
13	GTEx	Esophagus Mucosa	RIT1	0.06	0.04	lasso	8	0.03	2.9e-03	4.9	-5.2	1.8e-07	-0.79	0.07	0.90	FALSE
14	GTEx	Esophagus Mucosa	GBAP1	0.12	0.12	enet	22	0.09	1.7e-06	-4.1	-5.2	2.0e-07	-0.74	0.44	0.56	FALSE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	GBA	0.03	0.00	blup	26	0.02	3.1e-04	5.5	-5.2	2.1e-07	-0.91	0.02	0.83	FALSE
5	GTEx	Artery Coronary	HCN3	0.17	-0.01	lasso	6	-0.01	7.4e-01	5.1	-5.2	2.3e-07	-0.87	0.04	0.32	FALSE
11	GTEx	Colon Transverse	MSTO2P	0.21	0.05	lasso	11	0.08	7.7e-05	5.0	-5.2	2.5e-07	-0.80	0.12	0.87	FALSE
16	GTEx	Muscle Skeletal	MSTO2P	0.07	0.05	lasso	2	0.05	1.1e-05	5.4	-5.2	2.6e-07	-0.92	0.04	0.95	FALSE
20	GTEx	Skin Sun Exposed Lower leg	RIT1	0.09	0.09	lasso	5	0.06	5.9e-06	4.9	-5.2	2.7e-07	-0.70	0.06	0.94	FALSE
24	GTEx	Thyroid	RIT1	0.16	0.18	lasso	4	0.17	6.6e-13	5.2	-5.1	2.8e-07	-0.68	0.05	0.95	FALSE
15	GTEx	Esophagus Mucosa	GBA	0.28	0.30	enet	26	0.34	4.2e-23	4.6	-5.1	3.0e-07	-0.89	0.19	0.81	FALSE