TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Crohns Disease (2017)
:
←
→
chr1:113,751,640-115,152,814
Best TWAS P=1.09e-08 · Best GWAS P=6.42e-16 conditioned to 1.58e-09
113.8M
114M
114.2M
114.4M
114.6M
114.8M
115M
115.2M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
DCLRE1B
0.08
0.04
enet
14
0.05
2.6e-07
-5.7
5.7
1.1e-08
-0.50
0.97
0.03
TRUE
2
The Cancer Genome Atlas
Thyroid Carcinoma
DCLRE1B
0.06
0.04
enet
11
0.04
4.3e-05
-5.4
5.3
1.2e-07
-0.58
0.01
0.99
FALSE