TWAS
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Traits
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Traits
:
Crohns Disease (2017)
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chr5:140,789,933-142,230,251
Best TWAS P=1.49e-12 · Best GWAS P=4.12e-12 conditioned to 0.339
140.8M
141M
141.2M
141.4M
141.6M
141.8M
142M
142.2M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Muscle Skeletal
NDFIP1
0.20
0.10
lasso
9
0.12
3.8e-12
-6.9
7.1
1.5e-12
-0.93
0.01
0.99
TRUE
2
METSIM
Adipose
NDFIP1
0.23
0.15
lasso
8
0.16
7.1e-23
-6.7
-6.9
4.1e-12
0.73
0.02
0.98
FALSE