Hub : Genes

NDFIP1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Tibial 0.1972 0.0545 1.1e-03 0.073 NA 0.008 NA 0.036 2.4e-06 NA 6.7e-02 NA 8.0e-04
2 GTEx Liver 0.3510 0.1080 2.5e-03 -0.011 NA -0.010 NA -0.010 9.3e-01 NA 7.8e-01 NA 8.3e-01
3 GTEx Muscle Skeletal 0.2046 0.0399 4.5e-09 0.103 NA 0.115 NA 0.124 2.6e-10 NA 2.3e-11 NA 3.8e-12
4 GTEx Thyroid 0.1050 0.0360 2.9e-03 0.076 NA 0.099 NA 0.087 1.8e-06 NA 5.2e-08 NA 3.6e-07
5 METSIM Adipose 0.2323 0.0393 3.5e-14 0.147 0.122 0.153 0.137 0.158 2.2e-21 7.5e-18 3.3e-22 6.8e-20 7.1e-23
6 NTR Blood 0.0290 0.0104 1.2e-03 0.003 0.006 0.004 0.006 0.003 3.1e-02 2.9e-03 1.7e-02 4.1e-03 3.8e-02
7 YFS Blood 0.0380 0.0110 1.8e-05 0.014 0.015 0.031 0.025 0.013 2.1e-05 8.7e-06 2.3e-10 1.1e-08 2.7e-05
8 TCGA Breast Invasive Carcinoma 0.0371 0.0202 1.5e-03 0.014 0.010 0.007 NA 0.012 5.1e-04 2.8e-03 1.1e-02 NA 1.2e-03
9 TCGA Thyroid Carcinoma 0.0640 0.0270 2.6e-04 0.035 0.036 0.045 NA 0.042 2.3e-04 1.9e-04 3.3e-05 NA 5.9e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.6 0.9 2.7 1.3 -0.8 -0.1 1.0 0.4 -0.3 0.4 -1.3 1.6
Bipolar Disorder or Schizophrenia 0.7 1.7 6.6 2.6 0.2 0.0 1.8 0.0 0.3 -1.4 -1.4 1.0
Depressed Affect (Nagel 2018) 0.1 0.2 0.8 0.9 -0.3 0.3 0.3 0.0 -0.6 0.4 -0.1 0.1
Depression (Nagel 2018) 0.2 0.3 0.9 -0.9 -0.5 0.4 0.9 -0.4 -0.7 0.3 0.3 0.4
Intelligence (Savage-Jansen 2018) 0.6 1.8 5.4 -1.3 1.8 -0.9 0.7 0.3 1.4 2.3 -0.7 1.3
Neuroticism (Nagel 2018) 0.4 0.9 2.5 0.0 0.6 -1.6 0.3 1.5 0.4 1.5 -0.7 0.5
Schizophrenia (2018) 0.7 1.5 5.2 2.3 0.8 0.1 1.5 -0.3 0.6 -2.1 -0.8 -0.1
Schizophrenia vs Biploar Disorder 0.8 1.0 3.0 0.7 1.0 0.8 0.8 -0.8 -1.7 -1.4 -0.8 0.5
Worry (Nagel 2018) 0.4 0.8 3.1 -0.3 0.9 -1.7 -0.2 1.8 0.2 0.6 -0.3 -0.4
Alzheimer’s Disease (in mother) 1.3 1.5 4.1 -0.9 1.7 -1.7 -0.4 2.0 0.9 0.8 -1.1 -0.1
Alzheimer’s Disease (in father) 1.8 2.0 7.1 -2.0 1.5 -1.3 -0.8 0.8 0.9 2.7 0.9 -0.2
Alzheimer’s Disease (including proxy) 2.3 3.3 5.7 -1.7 2.2 -2.4 -0.5 2.2 2.2 2.3 -0.8 0.1
Crohns Disease (2017) 7.9 17.2 50.1 1.6 -2.3 7.1 2.0 -6.9 -3.0 -4.2 4.2 0.2
Irritable Bowel Disease (IBD) 5.3 12.6 40.1 1.2 -2.2 6.3 1.0 -5.6 -2.7 -3.7 3.6 0.0
Ulcerative Colitis (UC) 1.7 3.3 12.7 0.0 -0.9 3.6 -0.1 -2.6 -1.4 -1.8 1.9 -0.1
Major Depression (MDD) 0.8 0.9 3.6 0.2 0.1 1.6 0.6 -1.9 0.2 0.2 1.3 0.3
Reaction Time 0.1 0.1 0.3 0.5 0.0 -0.0 -0.4 0.1 -0.1 -0.4 -0.2 -0.6
Verbal and Numeric Reasoning (VNR) 0.6 1.5 4.8 -1.3 2.2 -0.5 0.1 0.3 0.9 2.2 -0.3 0.8
Breast Cancer 0.8 2.0 6.2 0.0 -2.1 1.5 -0.4 -1.6 -1.1 -1.0 2.5 -0.9
Ovarian Cancer 0.1 0.2 0.7 0.2 0.8 0.1 0.0 -0.2 -0.3 -0.5 0.5 -0.5
Prostate Cancer 1.5 2.2 7.3 -0.4 0.1 -1.7 0.6 1.7 2.7 1.4 -1.8 0.7
Age at First Birth 0.5 0.7 4.1 0.5 -0.1 -0.9 -0.2 0.9 -0.5 0.4 -2.0 0.1
Bipolar Disorder (2011) 0.3 0.3 0.7 0.6 -0.5 0.4 0.6 -0.2 0.8 0.4 0.2 0.8
Body Mass Index (BMI) (2010) 0.5 0.8 2.5 1.0 0.3 0.3 1.0 -0.1 0.1 -0.9 -1.6 1.2
Coronary Artery Disease (CAD) 0.7 0.8 4.5 2.1 -0.9 0.1 0.7 -0.8 -0.6 -0.7 -0.1 0.3
Crohns Disease (2012) 6.1 9.8 30.8 1.7 -1.8 5.5 1.6 -5.4 -1.9 -2.9 2.6 0.9
Mean Putamen Volume 0.8 0.9 3.0 0.7 -1.2 1.7 0.5 -1.1 -0.5 -0.2 -0.6 1.0
Fasting Glucose 0.7 0.8 1.7 1.1 -0.3 -0.6 -1.3 1.1 -0.0 1.0 0.8 -1.1
HbA1C 0.4 0.5 2.2 -0.3 -0.9 -0.1 -0.6 -0.2 -0.3 -0.0 1.5 -0.6
HDL Cholesterol 0.5 0.9 3.5 0.7 0.7 0.3 1.9 -0.7 0.1 0.5 -0.5 1.6
LDL Cholesterol 0.7 1.1 6.0 0.5 -2.4 0.3 0.1 -1.0 -0.0 -0.6 1.3 -0.7
Lupus 0.4 0.7 1.9 -0.8 -0.9 0.1 1.4 -0.4 -0.6 0.5 -0.7 1.2
Neuroticism (2016) 1.3 1.8 4.4 -0.8 0.8 -1.9 -1.2 2.1 0.6 1.9 -1.1 -0.4
Primary Biliary Cirrhosis 2.1 3.0 7.5 1.4 -1.6 2.7 1.9 -2.2 -1.3 -1.6 0.3 1.2
Rheumatoid Arthritis 1.9 2.6 7.7 -0.8 -2.5 0.3 -1.5 -0.8 -0.6 -0.7 2.8 -2.1
Schizophrenia (2014) 0.9 2.1 5.1 2.3 1.4 0.1 2.0 -0.2 0.1 -1.5 -1.9 1.2
Triglycerides 0.7 1.2 3.2 -0.8 0.3 -1.1 -1.8 1.2 0.7 -0.3 0.8 -1.8
Type 2 Diabetes (T2D) (2012) 1.3 1.5 4.2 -1.0 0.9 0.6 0.7 -1.1 1.2 2.0 -0.4 2.0
Ulcerative Colitis 0.9 1.3 4.9 0.4 -1.3 2.2 -0.3 -1.7 -0.5 -0.9 1.1 0.2
Blood Eosinophil Count 18.8 144.5 368.6 2.9 -12.0 19.2 -1.5 -16.1 -13.5 -11.0 13.5 -5.7
Blood Platelet Count 3.4 39.1 151.3 -0.1 -4.6 12.3 2.7 -10.0 -5.6 -1.7 5.4 3.0
Blood Red Count 0.9 8.9 29.5 1.8 -1.5 5.0 1.5 -5.4 -1.9 -1.9 3.2 -0.2
Blood White Count 7.8 58.1 127.7 1.8 -10.0 11.3 -2.8 -8.9 -7.8 -7.5 8.2 -4.5
Heel T-Score 0.2 1.4 2.6 -0.0 -1.6 1.5 -1.3 -1.3 -0.8 0.6 1.6 -0.6
BMI 0.3 1.7 10.2 3.2 -0.6 0.6 0.6 0.1 -0.7 -1.1 -1.5 0.3
Height 0.4 6.8 16.1 -3.0 2.1 -4.0 -2.6 3.1 0.4 1.7 1.3 -3.3
Waist Hip Ratio (WHR) 0.5 2.3 9.2 -3.0 0.4 -0.8 -1.4 0.7 0.8 1.0 2.2 -1.4
Systolic Blood Pressure 0.7 3.5 6.2 1.4 -2.4 1.9 -0.5 -2.2 -2.5 -1.7 2.1 -1.2
Smoking Status 0.2 0.4 1.6 0.0 0.1 -1.1 0.2 0.8 -0.0 0.1 -1.3 0.5
Allergy or Eczema 5.7 15.1 43.8 0.9 -1.4 6.6 0.5 -5.5 -6.2 -2.0 4.0 -0.5
Cardiovascular Disease 1.4 4.5 12.8 -1.3 -0.1 0.2 -3.6 0.2 -3.0 -0.5 2.5 -3.2
Hypothyroidism (self reported) 0.4 0.9 2.1 0.8 0.3 1.2 1.5 -1.3 -0.4 -1.2 0.1 0.2
Respiratory disease 10.5 23.4 53.1 1.7 -1.6 7.3 -2.0 -6.1 -5.9 -4.1 6.6 -3.8
Type 2 Diabetes (T2D) (2018) 1.3 2.3 6.1 -1.3 -1.9 0.1 -2.1 0.7 -2.5 -0.4 1.3 -1.6
Lung FEV1/FVC ratio 0.9 4.7 13.3 0.3 1.0 -2.0 2.5 1.2 2.4 1.3 -3.6 3.0
Lung FVC 0.3 1.7 7.0 -0.8 -0.4 -1.7 -0.5 1.5 2.6 -0.6 0.9 -1.2
Neuroticism 0.3 0.8 1.5 0.7 1.0 -1.0 1.2 0.9 0.1 0.7 -1.2 1.0
Chronotype (morning person) 0.2 0.5 1.9 -1.1 0.7 0.1 -0.2 1.4 0.5 -0.3 0.2 -0.8
Hair Pigment 0.1 2.2 5.5 -0.9 1.3 -2.3 0.7 1.6 1.7 1.4 -1.6 1.0
Tanning 0.1 0.9 1.8 -0.1 -0.5 1.1 -0.1 -1.3 -0.5 -1.3 1.3 -0.9
Hand grip strength (left) 0.1 0.2 0.9 0.6 -0.4 -1.0 -0.2 0.3 -0.6 0.0 0.0 -0.6
Number of treatments/medications taken 0.7 1.3 5.1 -0.0 -0.5 1.8 -0.3 -0.8 -2.3 -1.1 1.1 -0.4
Average weekly spirits intake 0.3 0.3 1.1 -0.7 0.1 0.6 -1.0 0.2 -0.5 0.2 0.9 -0.5
Sensitivity / hurt feelings 2.0 3.4 10.1 -1.2 0.9 -2.5 -2.3 3.2 1.4 1.7 0.1 -1.4
Frequency of depressed mood in last 2 weeks 0.2 0.2 0.9 0.2 -0.0 0.4 0.4 -0.2 -0.7 -0.9 0.5 -0.5
Hearing difficulty/problems: Yes 0.6 1.0 2.8 -0.1 0.9 -1.4 0.4 1.0 1.7 0.6 -0.8 1.1
Relative age of first facial hair 0.5 1.0 2.3 0.2 -1.1 1.0 -1.0 -0.1 -1.5 -1.2 0.9 -1.3
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 1.4 0.6 0.3 -0.1 0.1 0.2 -1.2 -0.3 -0.5 0.1
Ever used hormone-replacement therapy (HRT) 0.5 0.7 2.2 -0.6 0.7 -0.6 -1.5 1.3 0.6 -0.1 0.1 -0.8
Ever had hysterectomy (womb removed) 1.6 1.8 4.5 1.0 1.4 -0.3 2.0 -0.7 -0.0 0.1 -2.1 2.0
Systolic blood pressure, automated reading 0.6 1.7 3.3 1.7 -1.8 0.9 -0.5 -1.4 -1.5 -1.2 0.9 -1.2
Eye problems/disorders: Diabetes related eye disease 0.3 0.4 1.8 0.5 0.1 0.8 0.1 -0.7 -1.4 -0.2 -0.1 0.1
Angina 0.9 1.2 2.7 1.5 -1.6 0.3 -0.8 -0.6 -0.9 -1.2 0.6 -1.4
Medication for hormone replacement therapy 0.6 0.7 3.4 -1.9 -0.0 0.5 0.8 -0.1 0.0 0.7 -0.2 1.1
Vitamin and mineral supplements 0.7 0.9 3.0 -1.1 -0.7 0.5 -1.1 0.2 -0.2 -0.8 1.2 -1.7
Supplements: Zinc 1.1 1.2 4.2 -0.2 0.5 -1.3 0.1 1.4 0.9 2.1 -1.3 0.8
Medication: Co-codamol 1.4 1.6 5.5 -0.5 0.1 2.3 -0.6 -1.4 -1.4 -0.4 1.9 -0.6
Medication: Metformin 0.7 0.9 4.4 0.2 -2.1 -0.4 -0.8 1.0 -1.3 0.8 -0.1 -0.0
Diabetes (father) 0.2 0.2 0.6 -0.4 0.5 -0.4 0.4 0.2 -0.8 0.5 -0.2 0.3
Diabetes (mother) 0.1 0.1 0.4 -0.2 -0.6 0.2 -0.0 -0.1 -0.0 -0.4 0.5 -0.3
Severe depression (siblings) 0.8 0.9 3.9 0.8 -0.1 0.1 1.2 -0.3 -0.8 -0.1 -1.0 2.0
Pack years adult smoking proportion 0.5 0.8 3.3 0.2 -0.5 -0.9 -0.9 1.8 -0.4 1.0 -0.8 -0.3
Impedance of leg (right) 1.3 6.4 27.4 -2.6 -0.9 2.1 -1.4 -2.2 -0.6 -1.4 5.2 -3.0
Leg fat-free mass (left) 0.4 1.9 5.6 1.9 0.8 -1.8 0.5 1.8 -0.0 0.3 -2.4 0.4
Trunk fat percentage 0.7 2.7 6.4 0.8 -1.2 2.5 -0.9 -1.1 -2.2 -1.7 1.6 -1.9
Hand grip strength (right) 0.2 0.7 1.8 0.9 -0.9 -1.3 -0.3 0.5 -1.1 -0.4 -0.3 -0.9
Townsend deprivation index at recruitment 0.7 1.0 2.9 0.4 -1.0 1.5 -0.2 -1.0 -0.9 -1.7 0.7 -0.4
Current tobacco smoking 0.7 1.1 4.2 0.3 -0.2 -0.2 -1.1 0.7 -0.7 -2.0 0.3 -1.8
Average weekly fortified wine intake 1.2 1.4 3.4 -0.2 0.2 1.5 -1.0 -0.9 -1.8 -0.0 1.8 -1.3
Maternal smoking around birth 0.5 0.7 3.3 0.4 -1.8 1.1 0.7 -0.5 0.0 -0.8 0.5 -0.3
Fed-up feelings 0.4 0.8 3.3 -0.1 1.3 0.1 1.8 -0.4 0.7 0.3 -0.1 1.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.6 2.5 -1.6 -0.9 0.6 0.3 -0.4 -0.3 0.9 0.8 -0.1
Relative age voice broke 0.9 1.4 3.5 0.6 -1.9 0.8 -1.2 0.3 -0.9 -1.4 1.3 -1.4
Taking other prescription medications 2.1 3.2 7.4 -0.2 -1.2 2.7 -0.4 -1.4 -2.6 -2.3 2.2 -1.0
Age when periods started (menarche) 1.3 3.0 10.9 0.7 -1.2 1.8 -0.6 -1.1 -3.3 -2.0 1.7 -1.6
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 2.3 0.2 1.0 0.0 1.4 -0.5 0.0 0.0 -1.3 1.5
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 1.2 0.8 -0.6 0.6 0.6 -0.7 -0.8 0.5 -0.7 1.1
Tinnitus: Yes, but not now, but have in the past 1.1 1.2 3.7 -0.5 -0.0 0.8 -0.7 -0.5 -0.1 -1.5 1.9 -1.9
Qualifications: CSEs or equivalent 0.7 0.9 2.0 -1.4 0.1 -1.2 -0.8 1.2 1.0 -0.0 0.5 -1.0
Serious illness, injury or assault to yourself 0.7 0.8 3.1 0.6 -0.6 1.8 0.6 -1.4 -0.6 -0.6 -0.0 0.6
High blood pressure 0.4 1.1 2.9 -1.0 0.4 -1.3 -1.7 1.1 -1.0 0.9 0.3 -0.8
Hayfever, allergic rhinitis or eczema 4.1 8.9 28.9 1.5 -0.2 5.4 0.8 -4.2 -4.4 -1.4 3.1 -0.0
Multivitamins +/- minerals 1.1 1.4 4.5 0.6 0.7 -0.3 2.1 -0.6 1.1 0.5 -1.1 2.0
Stomach or abdominal pain in last month 0.1 0.2 0.8 -0.3 -0.9 -0.2 0.2 0.3 -0.6 -0.0 -0.1 -0.0
Supplements: Glucosamine 0.8 1.1 3.5 0.5 0.8 0.6 1.9 -1.2 0.7 -0.3 -0.7 1.5
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 1.6 1.0 -0.6 -0.0 -0.9 1.1 0.1 -1.3 -0.4 -1.2
Medication: Atenolol 0.3 0.4 1.0 -0.3 -1.0 0.7 0.2 -1.0 -0.6 -0.5 0.6 0.0
Medication: Levothyroxine sodium 1.1 1.9 4.7 2.2 0.5 -0.3 2.1 0.4 0.9 -0.3 -2.1 1.6
Sitting height 0.5 3.3 13.0 -0.5 2.1 -3.6 0.0 2.4 0.8 1.8 -1.6 -0.1
Chronic bronchitis/emphysema (father) 0.4 0.5 1.9 1.4 -0.7 -0.5 -0.3 0.6 -0.7 -0.7 -0.9 -0.2
High blood pressure (mother) 0.4 0.5 2.0 -0.9 -0.4 0.1 -0.7 -0.2 -1.4 0.9 0.2 -0.6
Body mass index (BMI) 0.3 1.4 6.8 2.6 -0.6 0.0 0.1 1.0 -0.5 -0.6 -2.0 0.4
Impedance of leg (left) 1.3 6.5 25.2 -3.1 -1.3 2.1 -1.8 -1.9 -0.8 -1.1 5.0 -3.0
Leg predicted mass (left) 0.3 1.7 5.1 1.9 0.8 -1.7 0.4 1.7 -0.0 0.2 -2.3 0.3
Trunk fat mass 0.2 1.0 2.6 0.7 -0.6 1.1 -0.9 0.0 -1.6 -1.0 0.7 -1.6
Waist circumference 0.2 0.6 2.5 0.5 0.2 -0.8 -1.0 1.6 -0.2 0.3 -0.5 -0.9
Number of incorrect matches in round 0.8 1.4 3.4 -0.2 0.6 -1.3 -1.7 1.9 1.1 0.6 0.5 -1.4
Past tobacco smoking 0.9 1.6 5.6 -0.3 -0.3 1.2 -1.7 -0.1 -0.2 -0.9 1.9 -2.4
Alcohol usually taken with meals 1.4 2.3 8.4 -0.5 2.9 -2.0 0.7 0.7 1.4 1.8 -1.2 0.6
Nervous feelings 0.6 1.1 2.9 0.3 0.5 -1.5 0.0 1.7 0.9 1.3 -1.4 0.3
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 2.2 0.4 0.1 -0.1 1.5 -0.3 0.7 -1.0 0.1 0.2
Hearing difficulty/problems with background noise 1.8 2.9 6.6 0.0 1.7 -2.0 1.5 1.0 2.6 1.9 -1.5 1.8
Hair/balding pattern: Pattern 2 1.5 1.9 7.2 -0.1 1.1 -2.1 0.3 0.7 2.7 1.7 -0.7 0.5
Had menopause 0.8 1.0 2.0 -1.2 0.3 -1.4 -1.3 1.2 1.2 0.8 0.0 -0.8
Had other major operations 1.1 1.3 3.3 1.8 1.2 0.2 1.7 -0.7 0.3 -0.3 -1.2 1.6
Forced vital capacity (FVC) 0.4 1.4 3.4 -1.0 1.7 -1.8 -0.1 1.0 1.8 0.4 0.7 -0.6
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.2 6.1 0.6 -1.6 2.2 0.8 -2.1 -2.5 -0.1 0.4 1.1
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 3.5 -0.2 -0.8 0.8 -1.3 -0.4 -0.8 -0.3 1.9 -0.9
Qualifications: None of the above 1.2 2.6 6.9 0.9 -0.2 1.9 -0.2 -1.6 -1.2 -2.6 2.3 -1.5
Financial difficulties in last 2 years 0.7 1.0 2.6 0.2 -1.4 1.4 -1.0 -0.4 -0.0 0.0 1.6 -1.0
Mouth/teeth dental problems 0.8 1.3 3.2 0.8 -0.6 1.7 1.0 -1.8 -1.0 -1.2 0.9 0.6
Heart attack 0.6 0.8 3.5 0.0 -1.9 -0.7 -0.8 0.6 0.2 1.1 0.7 -0.4
Allergy 6.4 14.8 46.8 -3.0 0.5 -6.8 -0.7 5.3 5.4 2.4 -3.6 0.5
Pain all over the body in last month 1.0 1.1 5.6 -0.7 -2.4 0.9 -1.1 -0.4 -0.1 -0.3 0.9 -0.9
Diabetes (self-reported) 0.8 1.2 4.1 -0.9 -1.0 -0.1 -1.3 0.7 -2.0 -0.2 0.8 -1.3
Hayfever/allergic rhinitis (self-reported) 3.2 4.3 13.7 1.1 -1.4 3.7 0.7 -2.6 -2.7 -1.8 2.0 0.2
Medication: Ramipril 0.3 0.4 1.9 -0.5 -0.2 0.0 0.3 -0.3 0.2 1.4 0.3 1.3
Medication: Simvastatin 0.9 1.3 4.3 -1.3 -1.1 -0.2 -2.1 0.7 -1.1 -0.1 0.6 -1.6
Fluid intelligence score 0.9 1.9 10.3 -1.4 3.2 -0.5 0.3 0.1 0.3 1.9 -0.2 0.8
Illnesses of siblings 1.5 2.1 6.9 -2.3 1.1 0.4 -1.1 -0.3 0.3 -0.0 2.6 -2.0
Neuroticism score 0.8 1.7 3.4 -0.3 1.3 -1.8 0.9 1.9 1.2 1.5 -1.4 0.9
Weight 0.2 1.1 2.9 1.7 0.2 -1.2 -0.2 1.6 -0.4 0.0 -1.6 -0.4
Impedance of arm (right) 1.4 6.4 17.3 -1.1 -0.4 4.1 0.4 -3.9 -1.5 -1.6 4.2 -1.3
Arm fat percentage (right) 0.5 2.1 6.0 2.5 -1.4 2.2 0.2 -0.8 -1.6 -1.7 0.0 -0.4
Trunk fat-free mass 0.6 3.7 13.4 1.0 1.1 -3.7 -0.4 3.0 1.0 1.4 -2.4 -0.1
Hip circumference 0.2 0.9 3.5 1.9 0.2 -0.3 -0.1 1.1 -0.8 -0.3 -1.4 -0.3
Time employed in main current job 0.4 0.5 1.3 0.1 0.3 0.1 0.4 1.0 -0.4 0.8 -1.1 1.1
Alcohol intake versus 10 years previously 0.9 1.3 6.1 0.7 -2.5 0.5 -1.5 0.8 -0.8 -0.9 -0.1 -0.7
Father’s age at death 3.1 4.1 6.9 -2.3 1.5 -2.5 0.2 2.6 2.1 2.0 -2.4 1.2
Worrier / anxious feelings 1.0 1.9 6.0 -0.6 1.7 -2.4 -0.7 2.4 0.6 1.0 -0.0 -0.8
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.4 1.2 0.8 -0.6 0.9 -0.0 -0.7 -0.0 -0.1 1.1 -0.5
Falls in the last year 0.3 0.4 1.0 -0.5 1.0 0.8 0.7 -0.5 0.8 -0.1 -0.1 0.9
Hair/balding pattern: Pattern 3 0.7 1.1 4.1 -0.5 -0.5 0.6 -2.0 0.3 -1.7 -0.8 0.3 -1.1
Number of live births 0.2 0.2 0.9 -0.1 -0.3 -0.0 -0.2 0.5 0.4 -1.0 0.4 -0.6
Forced expiratory volume in 1-second (FEV1) 0.5 1.8 7.3 -0.8 1.3 -1.9 0.8 1.0 2.7 0.8 -0.6 0.7
Pulse rate 0.6 1.1 2.6 1.3 -1.3 1.0 0.7 -0.8 -1.2 -1.6 0.2 -0.5
Happiness 0.4 0.5 1.8 0.1 -0.9 0.1 0.1 0.3 0.8 1.3 -0.3 0.9
Noisy workplace 0.7 0.8 3.0 -0.7 0.4 -1.4 -0.2 1.7 1.0 0.7 -0.6 -0.1
Qualifications: A levels/AS levels or equivalent 1.5 3.2 6.6 -0.5 1.6 -2.6 0.8 1.8 1.8 2.6 -1.8 1.6
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.4 1.5 0.9 -1.2 0.4 0.5 -0.5 0.8 0.3 0.0 0.3
Mouth/teeth dental problems: Dentures 0.3 0.5 4.2 -0.1 -2.0 0.3 -0.4 -0.2 -0.2 -0.1 0.0 -0.2
Asthma 6.5 12.7 36.4 2.7 -1.6 6.0 -0.7 -4.6 -4.2 -3.0 4.1 -2.0
Medication: Ibuprofen (e.g. Nurofen) 1.5 1.9 5.6 0.6 2.4 -1.2 1.1 0.9 0.9 0.8 -2.2 1.1
Medication: Cholesterol lowering 1.3 2.0 5.5 -0.9 -1.7 -0.4 -2.3 1.3 -1.9 0.5 0.6 -1.5
Depression (self-reported) 0.1 0.2 0.5 -0.3 -0.2 -0.4 -0.0 0.7 -0.7 -0.1 -0.1 0.2
Medication: Lansoprazole 1.0 1.2 3.3 -1.6 0.2 -0.1 -1.8 0.5 0.3 1.0 1.4 -1.2
Prospective memory result 0.3 0.4 1.7 1.3 0.9 -0.2 0.6 0.3 0.4 -0.1 -0.6 0.5
Lung cancer (father) 0.9 1.1 1.9 1.3 1.3 -1.4 -0.1 0.9 1.2 -0.9 -1.0 -0.3
Illnesses of mother 0.8 0.9 2.4 1.1 0.7 0.6 1.6 -0.8 1.0 -0.5 -0.2 1.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.5 6.7 -0.8 0.6 -1.9 0.3 1.4 2.6 0.3 -0.2 -0.0
Pulse wave Arterial Stiffness index 0.3 0.4 1.6 -0.2 -0.8 0.2 1.3 -0.2 0.3 -0.1 -0.2 1.0
Impedance of arm (left) 1.1 5.2 13.5 -1.7 -0.1 3.5 0.8 -3.7 -1.7 -1.4 3.4 -0.8
Arm fat mass (right) 0.3 1.2 5.4 2.3 -1.0 0.6 -0.3 0.5 -1.0 -1.2 -0.8 -0.6
Trunk predicted mass 0.6 3.6 13.1 1.0 1.0 -3.6 -0.5 3.0 0.9 1.4 -2.3 -0.3
Standing height 0.3 2.7 6.7 -2.0 1.6 -2.6 -1.1 1.6 0.1 1.1 1.0 -2.2
Length of working week for main job 0.5 0.6 2.5 -1.2 0.4 -0.4 0.0 -0.0 1.6 0.8 0.2 0.1
Exposure to tobacco smoke at home 0.1 0.1 0.3 0.2 -0.3 0.5 -0.1 -0.2 -0.2 -0.5 0.3 -0.1
Breastfed as a baby 4.2 5.2 9.5 1.1 2.8 -2.9 1.8 2.0 2.6 1.5 -3.1 2.0
Tense / ‘highly strung’ 1.2 2.0 4.9 -0.6 1.9 -2.1 0.6 2.2 1.1 1.6 -1.0 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.5 3.5 -0.3 0.9 -1.5 -0.1 1.9 0.8 1.7 -1.7 0.9
Hair/balding pattern: Pattern 4 0.1 0.3 0.7 0.6 -0.7 -0.8 0.2 0.5 0.5 -0.4 -0.8 -0.4
Birth weight of first child 0.6 1.1 4.6 0.1 2.1 -1.1 -0.8 1.5 0.5 0.6 -0.5 -0.8
Peak expiratory flow (PEF) 2.0 4.7 14.6 0.0 1.4 -1.6 2.5 0.3 3.8 1.6 -2.0 3.1
Pulse wave reflection index 0.5 0.6 1.2 -0.7 0.7 -0.6 0.8 0.9 1.0 0.3 -0.4 1.1
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.7 -0.0 -0.7 1.3 0.0 -1.0 -0.3 -1.1 0.9 -0.7
Loud music exposure frequency 0.8 0.9 2.3 1.4 -1.5 0.8 -0.9 -0.7 -0.2 -0.8 0.8 -0.8
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 2.1 -0.1 0.3 -0.7 0.3 0.5 1.4 0.9 -0.8 0.9
Mouth/teeth dental problems: Bleeding gums 0.9 1.1 3.7 -0.3 1.3 -0.7 -1.7 1.9 0.5 0.1 -0.2 -1.1
Blood clot in the leg (DVT) 0.8 1.1 4.1 0.3 2.0 -1.0 0.0 1.3 -0.1 1.5 -0.7 0.3
Medication: Paracetamol 0.8 1.3 3.3 0.1 -0.3 1.7 -0.4 -1.5 -1.4 -0.6 1.8 -1.1
Headache pain in last month 0.4 0.7 1.8 -1.4 -0.3 0.6 -0.5 -0.4 -0.1 0.2 1.3 -1.3
Medication for cholesterol, blood pressure or diabetes 1.3 2.1 4.8 1.3 1.4 0.1 2.2 -0.6 2.2 0.6 -1.2 1.8
Glaucoma (self-reported) 1.0 1.2 2.5 -1.6 1.6 -0.6 -1.0 0.3 0.7 0.1 1.4 -1.3
Gout (self-reported) 0.3 0.4 0.9 0.6 0.9 -0.5 -0.0 0.8 0.0 -0.9 0.1 -0.9
Hypothyroidism/myxoedema (self-reported) 0.5 0.9 2.7 1.6 -0.0 0.7 1.6 -0.9 -0.4 -1.0 -0.2 0.8
Medication: Amlodipine 0.6 0.8 2.9 0.5 -0.9 -0.1 0.3 -0.6 -1.7 -1.7 -0.3 -0.6
Medication: Ventolin 100micrograms inhaler 5.4 6.9 18.8 1.3 -2.3 4.3 -1.1 -3.4 -3.6 -1.0 3.0 -1.1
Birth weight 1.2 2.5 9.4 -0.3 0.8 -0.5 -3.1 1.5 -0.8 -0.1 1.0 -2.9
Chronic bronchitis/emphysema (mother) 1.2 1.4 3.8 1.0 -1.9 1.1 -0.2 -0.7 -0.5 -1.9 1.1 -1.1
High blood pressure (siblings) 1.2 1.7 5.6 1.0 -1.6 -0.9 0.7 0.6 0.6 0.7 -2.4 2.0
Forced vital capacity (FVC), Best measure 0.2 0.8 2.5 -0.9 0.5 -1.2 0.0 0.7 1.6 -0.0 0.9 -0.8
Body fat percentage 0.5 2.1 5.1 1.2 -1.4 2.3 -0.8 -0.7 -1.8 -1.5 1.2 -1.5
Leg fat percentage (right) 0.3 0.9 1.5 1.1 -1.1 1.2 -0.7 -0.0 -0.8 -0.9 0.8 -1.2
Arm fat-free mass (right) 0.5 2.8 9.3 0.5 0.5 -3.0 -1.1 3.0 0.3 1.0 -1.9 -0.7
Exposure to tobacco smoke outside home 0.8 1.1 4.6 2.1 -0.8 -0.8 0.7 0.5 0.5 -1.5 -0.9 0.1
Comparative body size at age 10 0.4 1.1 3.0 1.7 -1.6 0.7 1.3 -0.6 0.8 -0.7 -0.4 0.6
Number of full brothers 0.8 1.0 2.6 -0.8 1.6 -0.4 -1.0 0.8 1.3 1.1 1.0 -0.5
Worry too long after embarrassment 1.4 2.3 5.6 -0.4 0.8 -2.4 1.1 2.3 1.0 1.3 -1.7 1.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.1 2.6 -1.6 1.2 -0.2 -1.4 0.9 0.3 0.5 1.3 -1.0
Wheeze or whistling in the chest in last year 1.7 3.1 6.9 -0.7 -2.3 1.4 -2.2 -0.4 -1.2 -0.6 2.6 -2.5
Number of children fathered 0.4 0.4 1.3 -1.1 -0.6 -0.3 -1.0 0.8 0.6 0.0 -0.3 -0.5
Reason for reducing amount of alcohol drunk: Health precaution 2.2 2.6 6.7 0.2 0.9 -2.6 1.1 2.0 0.8 1.4 -2.4 1.5
Age at first live birth 0.2 0.3 1.1 -0.1 0.7 -0.9 -0.2 0.2 0.5 1.1 0.2 -0.4
Pulse wave peak to peak time 0.4 0.5 1.6 0.1 1.0 -0.4 -1.2 0.2 -0.2 0.1 0.2 -1.2
Health satisfaction 1.1 1.4 3.1 -0.9 -1.2 -1.6 -0.6 1.8 1.4 1.5 -0.5 0.3
Shortness of breath walking on level ground 0.8 1.0 4.9 -0.7 -2.2 1.4 0.6 -0.7 -0.0 0.1 0.5 0.7
Qualifications: College or University degree 0.7 2.3 6.5 0.8 2.6 -0.5 2.1 -0.8 -0.4 1.5 -1.0 2.2
Eye problems/disorders: None of the above 0.2 0.3 1.0 0.3 -1.0 -0.2 0.4 0.5 0.2 -0.3 -0.3 0.7
Mouth/teeth dental problems: Loose teeth 0.5 0.5 2.1 -0.6 -0.8 0.9 -0.5 0.3 -1.5 -0.1 -0.5 0.5
Emphysema/chronic bronchitis 1.7 1.9 4.5 -1.8 1.3 -1.0 -2.1 1.8 0.1 0.6 0.7 -1.5
Medication for pain relief, constipation, heartburn 0.4 0.7 1.9 0.3 0.1 -1.3 0.1 0.8 1.4 -1.0 -1.1 -0.0
Neck or shoulder pain in last month 1.0 1.4 6.6 -1.8 2.6 -0.6 1.0 0.5 0.6 0.8 -0.2 0.5
Medication: Blood pressure 0.9 1.6 6.2 -0.5 -1.5 0.4 -1.4 -0.0 -2.5 -1.0 0.8 -1.2
Angina (self-reported) 0.8 1.0 2.2 1.4 -1.5 0.1 -0.7 -0.3 -0.7 -1.2 0.5 -1.5
Migraine (self-reported) 0.3 0.4 2.0 -0.2 -1.4 -0.1 -0.6 0.4 0.4 0.9 0.4 0.5
Medication: Ibuprofen 1.8 2.2 5.6 1.3 2.4 -0.8 2.0 0.4 0.8 -0.0 -2.3 1.3
Medication: Allopurinol 0.7 0.9 1.9 -0.2 1.4 -1.2 -0.3 1.3 1.0 -0.3 0.6 -1.1
Medication: Omeprazole 2.7 3.2 8.8 -0.8 -1.7 3.0 -0.8 -2.2 -1.8 -0.9 2.5 -0.8
Medication: Seretide 50 evohaler 0.4 0.5 2.4 0.9 0.6 1.5 -0.1 -0.4 -0.5 -0.4 0.6 -0.2
Mean time to correctly identify matches 0.1 0.1 0.4 -0.1 0.2 -0.2 -0.6 0.4 -0.1 0.1 -0.1 -0.6
Heart disease (mother) 0.6 0.7 1.4 -0.8 -1.2 -0.8 -0.8 0.7 1.1 0.7 -0.1 -1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.2 0.6 -0.1 0.5 -0.6 -0.5 0.7 -0.6 0.7 -0.2 -0.1
Whole body fat mass 0.2 0.8 1.8 1.3 -0.7 0.5 -0.9 0.7 -1.3 -0.7 -0.1 -1.3
Leg fat mass (right) 0.2 0.6 1.8 1.4 -0.6 0.3 -0.6 0.7 -0.6 -0.8 -0.1 -1.1
Arm predicted mass (right) 0.6 3.0 10.5 0.7 0.5 -3.2 -1.0 3.0 0.4 0.9 -2.0 -0.6
Pulse rate, automated reading 1.9 6.3 13.2 1.6 -1.7 3.3 0.2 -2.6 -3.5 -3.6 2.1 -1.9
Alcohol intake frequency. 0.1 0.3 0.9 -0.2 -0.8 0.3 0.6 0.3 0.5 0.3 -0.7 1.0
Comparative height size at age 10 0.4 2.2 6.7 -2.0 -0.6 -0.8 -1.8 0.2 -1.1 -0.3 1.7 -2.6
Number of full sisters 1.1 1.3 3.4 1.9 0.1 -0.7 1.4 0.3 1.2 -0.0 -1.6 1.4
Suffer from ‘nerves’ 0.8 1.2 4.2 -0.4 0.9 -2.1 -0.5 1.7 1.1 0.7 -0.5 -0.3
Overall health rating 0.4 1.0 2.3 0.2 -1.5 0.3 -0.9 0.8 -1.5 -1.1 0.6 -1.0
Chest pain or discomfort 0.4 0.5 1.5 0.7 0.5 0.3 -0.8 -0.6 -0.1 -0.1 1.2 -1.2
Had major operations 0.7 0.8 3.4 1.0 -0.2 0.6 -0.3 0.3 -1.1 1.8 -0.3 0.8
Age at last live birth 0.2 0.2 0.8 0.4 0.1 -0.1 -0.9 0.1 -0.4 0.5 0.4 -0.7
Family relationship satisfaction 0.1 0.1 0.4 0.4 -0.2 0.4 -0.3 0.0 0.6 -0.3 0.2 -0.4
Leg pain on walking 1.4 1.7 4.6 0.2 0.1 -1.4 0.7 2.0 1.5 0.5 -2.1 1.3
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 1.1 0.4 -0.8 1.1 -0.6 -0.0 0.5 0.3 -0.6 0.2
Commuting to job workplace: Car/motor vehicle 1.6 1.8 4.8 -1.6 0.1 -1.4 -1.6 1.5 1.3 2.2 -0.1 -0.6
Illness, injury, bereavement, stress in last 2 years 1.0 1.2 3.2 -0.7 1.6 -1.8 0.7 0.7 0.7 0.9 -1.3 0.7
Medication: Aspirin 0.4 0.5 2.4 0.2 -0.4 -0.3 0.3 0.4 -0.6 1.5 -0.2 0.9
Supplements: Vitamin C 1.1 1.3 3.2 0.9 1.4 -1.0 0.4 0.8 -0.2 1.2 -1.6 1.8
Knee pain experienced in last month 0.7 1.0 2.8 1.6 -0.5 -0.6 0.3 0.8 1.7 -1.5 -0.1 -0.7
Hypertension (Self-reported) 0.3 0.9 3.0 -0.9 0.3 -0.9 -1.7 0.9 -1.2 0.6 0.4 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.1 1.3 3.5 -1.9 -0.7 0.9 -1.5 0.0 -0.7 1.1 1.5 -0.4
Illnesses of father: Heart disease 2.4 3.3 8.9 1.0 -2.4 2.6 1.0 -3.0 -1.8 -1.1 1.3 0.2
Illnesses of siblings: Diabetes 1.2 1.5 4.5 1.8 -1.3 -0.6 1.6 0.0 -0.2 -0.6 -2.1 1.1
Smoking status: Previous 1.6 2.4 9.7 -0.0 0.1 -0.8 2.3 -0.5 0.3 1.4 -1.9 3.1
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.5 2.2 -0.1 0.7 -1.5 0.2 0.8 0.3 0.6 -0.1 -0.4
Whole body fat-free mass 0.5 2.8 8.6 1.4 0.8 -2.9 -0.1 2.6 0.5 1.0 -2.5 0.1
Leg fat-free mass (right) 0.4 2.2 7.5 1.7 0.9 -1.9 0.5 1.9 -0.1 0.6 -2.7 0.6
Arm fat percentage (left) 0.5 1.8 4.3 2.1 -1.4 2.0 0.2 -0.7 -1.6 -1.6 -0.2 -0.3
Average weekly red wine intake 1.5 2.2 6.8 -1.0 2.6 -0.6 1.2 0.3 0.2 1.9 -1.6 1.9
Handedness (chirality/laterality): Left-handed 0.7 0.8 2.7 0.4 -0.2 1.6 0.4 -0.9 -1.2 -1.2 0.3 0.7
Mood swings 0.3 0.5 1.3 0.4 0.7 -0.9 -0.6 1.0 -0.5 0.2 -0.2 -1.1
Loneliness, isolation 0.8 1.1 3.3 -0.4 -1.8 0.6 -1.4 0.1 -0.7 0.1 1.3 -1.5
Long-standing illness, disability or infirmity 0.1 0.2 0.7 0.4 -0.1 -0.5 -0.1 0.5 -0.6 -0.8 0.2 -0.3
Ever had bowel cancer screening 0.5 0.5 1.0 -0.3 0.8 1.0 -0.9 -0.2 -0.8 0.7 0.9 -0.5
Diabetes diagnosed by doctor 0.7 1.1 4.3 -0.8 -1.3 -0.1 -1.2 0.7 -2.1 -0.2 0.9 -1.0
Ever had stillbirth, spontaneous miscarriage or termination 0.9 1.0 2.8 1.2 -1.4 1.2 -0.3 -1.0 -1.7 -0.4 0.3 -0.2
Friendships satisfaction 0.5 0.7 1.8 0.1 -0.0 0.6 1.3 -0.8 1.0 0.5 0.1 1.3
Qualifications: nursing, teaching 0.7 1.1 2.7 0.9 1.0 -0.9 1.3 0.0 1.6 0.6 -1.3 0.9
Commuting to job workplace: Walk 0.6 0.6 1.5 0.3 -1.1 0.7 1.2 -1.0 0.5 -0.3 0.7 0.6
Eye problems/disorders: Cataract 0.7 0.8 1.6 -0.2 -1.1 0.7 -0.8 -0.9 -1.0 -0.9 0.5 -1.3
Mouth/teeth dental problems: Mouth ulcers 1.6 2.5 8.8 1.0 3.0 -2.6 0.7 1.4 1.4 0.6 -1.2 -0.1
Medication for cholesterol 0.3 0.5 1.3 0.8 -0.4 0.3 1.0 -1.1 0.1 -1.0 -0.0 0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.1 2.4 7.1 -0.2 0.0 -1.9 1.6 1.3 1.2 1.0 -2.7 2.1
Back pain experienced in last month 0.6 0.9 2.2 0.4 0.1 -1.2 -0.3 1.5 1.3 1.1 -1.1 -0.2
Mineral and other dietary supplements 0.5 0.7 1.9 0.2 -1.4 -0.2 -1.2 1.1 -0.9 -0.4 -0.1 -0.7
Breast cancer (self-reported) 0.3 0.3 0.9 0.4 -0.1 0.2 -0.9 -0.2 -0.8 -0.1 0.5 -1.0
Asthma (self-reported) 6.5 12.9 37.1 2.5 -1.2 6.1 -0.6 -4.7 -4.2 -3.0 4.2 -2.0
Osteoporosis (self-reported) 0.3 0.4 2.3 -0.2 -1.5 -0.7 -0.6 0.5 -0.5 0.0 0.1 -0.4
Osteoarthritis (self-reported) 0.4 0.5 2.2 -0.1 0.6 0.8 0.7 -0.7 1.5 -0.2 0.6 0.2
Medication: Aspirin 0.2 0.3 0.9 0.6 -0.6 -0.4 0.1 0.5 -0.7 0.9 -0.2 0.4
Medication: Gliclazide 1.0 1.2 2.5 -1.3 -1.3 -1.3 -1.1 1.2 -0.3 1.6 -0.3 -0.4
Illnesses of father: None of the above (group 1) 2.1 2.6 6.5 0.1 1.5 -2.2 0.3 2.5 2.5 -0.1 -1.7 0.5
Smoking status: Current 0.7 1.1 3.6 0.4 -0.3 -0.1 -1.2 0.7 -0.8 -1.7 0.5 -1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 4.8 -0.8 1.0 -0.9 0.2 0.7 2.2 0.1 -0.0 0.4
Whole body water mass 0.5 2.8 8.9 1.3 0.9 -3.0 -0.2 2.7 0.6 1.0 -2.4 0.0
Leg predicted mass (right) 0.4 2.2 7.3 1.6 0.8 -2.0 0.4 2.0 -0.1 0.6 -2.7 0.6
Arm fat mass (left) 0.3 1.1 4.3 2.1 -1.0 0.6 -0.0 0.4 -1.1 -1.2 -0.9 -0.4
Number of self-reported non-cancer illnesses 2.1 3.7 10.6 0.3 -0.5 2.3 -1.7 -1.2 -3.3 -1.1 2.7 -2.0
Average weekly champagne plus white wine intake 0.6 0.8 1.7 0.1 -0.2 -1.3 0.6 1.3 1.2 0.8 -1.0 0.5
Miserableness 0.8 1.3 4.7 -0.4 1.2 -1.3 -0.1 1.1 1.1 2.2 -1.0 0.3
Guilty feelings 1.8 2.7 6.0 -0.5 0.7 -1.8 0.3 2.3 0.9 2.4 -2.3 1.6
Wears glasses or contact lenses 1.1 1.2 3.6 -0.2 0.0 -1.6 -1.0 1.9 0.9 1.7 -0.3 -0.2
Ever taken oral contraceptive pill 0.7 0.8 2.1 1.1 -0.6 1.2 0.8 -1.0 -0.7 -1.4 -0.2 0.2
Hearing aid user 1.1 1.2 5.8 2.4 0.2 -0.6 0.7 0.2 0.1 -0.6 -1.9 0.0
Mother’s age at death 3.3 4.1 9.7 -1.5 1.9 -3.1 0.1 2.0 1.4 2.6 -2.5 1.4
Financial situation satisfaction 0.8 1.0 3.0 0.4 -0.3 -1.7 0.0 1.6 1.4 1.1 -0.7 0.4
Tinnitus: Yes, now most or all of the time 0.4 0.5 1.7 0.1 1.0 -0.1 0.9 -0.3 1.3 0.1 -0.7 0.5
Commuting to job workplace: Public transport 0.2 0.2 0.6 -0.6 0.2 0.1 -0.8 0.6 -0.3 0.6 0.0 0.2
Eye problems/disorders: Glaucoma 0.8 0.9 2.9 -1.7 1.0 -0.7 -1.0 1.1 0.7 0.8 0.6 -0.6
Medication: Blood pressure 0.3 0.5 1.3 -0.2 0.8 -0.7 -0.4 1.2 0.5 1.0 -0.7 0.3
Pain type(s) experienced in last month: Hip pain 1.0 1.3 4.2 0.7 0.4 -1.4 1.7 0.4 1.0 -0.7 -2.0 0.7
Supplements: Fish oil (including cod liver oil) 0.7 0.9 3.2 -1.2 1.8 -0.6 0.6 -0.2 1.4 0.6 0.4 0.3
High cholesterol (Self-reported) 1.5 2.6 11.7 -0.6 -1.7 -0.5 -3.4 1.6 -0.9 0.3 0.7 -2.2
Medication: Bendroflumethiazide 0.4 0.7 1.6 0.7 0.6 0.6 0.5 -0.7 -1.0 -0.4 -1.2 1.0
Medication: Paracetamol 0.8 1.2 3.2 0.3 -0.0 1.0 -0.7 -0.8 -1.1 -1.0 1.8 -1.8
Medication: Lisinopril 1.3 1.7 5.1 -0.8 -0.0 -1.1 -2.2 1.5 -0.4 0.1 0.8 -2.3
Medication: Atorvastatin 0.8 1.0 5.3 0.6 -1.2 0.9 -0.3 -0.4 -2.3 -0.0 0.9 -0.4
Illnesses of father: High blood pressure 0.3 0.4 0.9 -0.7 -0.1 0.9 -0.0 -1.0 -0.9 0.4 0.4 0.4
Alcohol drinker status: Never 0.2 0.3 0.8 -0.9 -0.9 0.2 -0.2 0.2 -0.3 0.6 -0.1 0.6
Ever smoked 1.1 1.9 6.4 0.4 0.4 -1.5 1.5 0.5 0.7 0.2 -2.5 2.2
Basal metabolic rate 0.4 2.2 6.0 1.6 0.7 -2.5 -0.1 2.3 0.3 0.6 -2.3 -0.0
Leg fat percentage (left) 0.2 0.9 1.8 0.8 -1.4 1.0 -1.0 0.3 -0.9 -0.8 0.5 -1.2
Arm fat-free mass (left) 0.6 2.9 8.8 1.4 0.7 -3.0 -1.0 3.0 0.4 0.9 -1.9 -0.7
Number of operations (self-reported) 0.3 0.5 1.5 1.2 0.6 0.5 0.4 -0.1 -0.6 0.6 -0.7 1.0
Average weekly beer plus cider intake 0.9 1.2 4.0 -0.6 -2.0 -0.3 -1.0 0.4 -0.3 -1.6 0.9 -1.4
Irritability 1.3 2.2 5.7 0.7 2.4 -0.9 2.1 0.3 0.1 1.0 -1.6 2.3
Risk taking 2.3 3.4 7.2 -0.3 2.7 -2.7 -0.0 2.4 2.0 2.0 -1.5 0.1
Ever had prostate specific antigen (PSA) test 1.7 2.0 6.7 0.4 0.3 0.3 2.6 -1.2 -0.0 0.8 -1.6 2.5
Fractured/broken bones in last 5 years 0.4 0.5 1.9 -0.7 -0.5 0.5 -0.8 -0.2 0.1 -0.2 0.9 -1.4
Age started oral contraceptive pill 0.6 0.7 2.3 -0.1 1.1 -1.5 -0.5 0.6 0.4 1.3 -0.0 -0.5
Diastolic blood pressure, automated reading 0.7 2.1 4.4 0.5 -1.2 1.4 -0.6 -1.4 -2.1 -1.9 1.6 -1.5
Ever depressed for a whole week 0.2 0.3 1.5 -0.1 -0.1 -0.4 -0.6 0.5 1.2 0.3 0.3 0.2
Unable to work because of sickness or disability 0.2 0.3 0.6 -0.8 -0.2 0.4 -0.6 0.2 -0.1 -0.5 0.7 -0.8
Commuting to job workplace: Cycle 0.8 1.0 2.8 0.9 0.4 1.0 -0.8 -0.7 -1.7 -0.9 1.1 -1.0
Myopia 0.5 0.7 1.9 -0.2 -0.4 -1.1 -0.0 0.1 1.2 -0.6 1.1 -1.4
Vascular/heart problems diagnosed by doctor 0.3 0.9 2.5 0.5 -0.1 1.2 1.6 -1.0 0.9 -0.6 -0.4 1.0
Cholesterol lowering medication 0.4 0.6 1.8 -0.1 -1.2 0.5 -1.3 0.2 -0.6 -0.5 0.6 -0.8
Medication: Omeprazole (e.g. Zanprol) 3.0 3.6 10.0 -0.7 -1.3 3.2 -0.5 -2.7 -1.8 -0.9 2.8 -0.9
Pain experienced in last month 0.2 0.3 2.1 -0.2 1.4 -0.0 -0.5 -0.1 0.2 0.6 0.4 -0.1
Supplements: Calcium 1.0 1.1 1.9 -1.0 0.5 -1.3 -0.5 1.3 0.9 1.3 -1.4 1.0
Basal cell carcinoma (self-reported) 0.6 0.7 1.6 1.0 0.1 0.7 0.7 -1.0 0.0 1.2 -0.1 1.3
Heart attack/myocardial infarction (self-reported) 0.7 0.9 4.5 -0.1 -2.1 -0.5 -0.9 0.5 0.2 1.1 1.0 -0.5
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 2.2 0.3 1.5 -0.8 0.0 1.1 -0.3 1.0 -0.4 0.1
Heart disease (siblings) 0.5 0.6 2.2 0.8 -0.6 -0.4 0.5 1.0 0.2 -0.0 -1.5 0.7
Alcohol drinker status: Previous 0.8 0.9 2.9 -1.7 0.6 -0.6 0.3 0.9 1.2 1.0 -0.8 0.6
Pack years of smoking 0.8 1.1 4.5 -0.0 -0.2 -1.3 -1.0 2.1 -0.2 1.4 -1.0 -0.2
Impedance of whole body 1.4 7.0 23.9 -2.6 -0.8 3.3 -0.8 -3.1 -1.6 -1.4 4.9 -2.4
Leg fat mass (left) 0.2 0.6 1.4 1.2 -0.7 0.1 -0.8 1.0 -0.7 -0.6 -0.3 -1.0
Arm predicted mass (left) 0.5 2.7 8.7 1.2 0.6 -2.8 -1.2 3.0 0.2 0.8 -1.8 -0.8