Hub : Genes

NDFIP1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1972	0.0545	1.1e-03	0.073	NA	0.008	NA	0.036	2.4e-06	NA	6.7e-02	NA	8.0e-04
2	GTEx	Liver	0.3510	0.1080	2.5e-03	-0.011	NA	-0.010	NA	-0.010	9.3e-01	NA	7.8e-01	NA	8.3e-01
3	GTEx	Muscle Skeletal	0.2046	0.0399	4.5e-09	0.103	NA	0.115	NA	0.124	2.6e-10	NA	2.3e-11	NA	3.8e-12
4	GTEx	Thyroid	0.1050	0.0360	2.9e-03	0.076	NA	0.099	NA	0.087	1.8e-06	NA	5.2e-08	NA	3.6e-07
5	METSIM	Adipose	0.2323	0.0393	3.5e-14	0.147	0.122	0.153	0.137	0.158	2.2e-21	7.5e-18	3.3e-22	6.8e-20	7.1e-23
6	NTR	Blood	0.0290	0.0104	1.2e-03	0.003	0.006	0.004	0.006	0.003	3.1e-02	2.9e-03	1.7e-02	4.1e-03	3.8e-02
7	YFS	Blood	0.0380	0.0110	1.8e-05	0.014	0.015	0.031	0.025	0.013	2.1e-05	8.7e-06	2.3e-10	1.1e-08	2.7e-05
8	TCGA	Breast Invasive Carcinoma	0.0371	0.0202	1.5e-03	0.014	0.010	0.007	NA	0.012	5.1e-04	2.8e-03	1.1e-02	NA	1.2e-03
9	TCGA	Thyroid Carcinoma	0.0640	0.0270	2.6e-04	0.035	0.036	0.045	NA	0.042	2.3e-04	1.9e-04	3.3e-05	NA	5.9e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.6	0.9	2.7	1.3	-0.8	-0.1	1.0	0.4	-0.3	0.4	-1.3	1.6
Bipolar Disorder or Schizophrenia	0.7	1.7	6.6	2.6	0.2	0.0	1.8	0.0	0.3	-1.4	-1.4	1.0
Depressed Affect (Nagel 2018)	0.1	0.2	0.8	0.9	-0.3	0.3	0.3	0.0	-0.6	0.4	-0.1	0.1
Depression (Nagel 2018)	0.2	0.3	0.9	-0.9	-0.5	0.4	0.9	-0.4	-0.7	0.3	0.3	0.4
Intelligence (Savage-Jansen 2018)	0.6	1.8	5.4	-1.3	1.8	-0.9	0.7	0.3	1.4	2.3	-0.7	1.3
Neuroticism (Nagel 2018)	0.4	0.9	2.5	0.0	0.6	-1.6	0.3	1.5	0.4	1.5	-0.7	0.5
Schizophrenia (2018)	0.7	1.5	5.2	2.3	0.8	0.1	1.5	-0.3	0.6	-2.1	-0.8	-0.1
Schizophrenia vs Biploar Disorder	0.8	1.0	3.0	0.7	1.0	0.8	0.8	-0.8	-1.7	-1.4	-0.8	0.5
Worry (Nagel 2018)	0.4	0.8	3.1	-0.3	0.9	-1.7	-0.2	1.8	0.2	0.6	-0.3	-0.4
Alzheimer’s Disease (in mother)	1.3	1.5	4.1	-0.9	1.7	-1.7	-0.4	2.0	0.9	0.8	-1.1	-0.1
Alzheimer’s Disease (in father)	1.8	2.0	7.1	-2.0	1.5	-1.3	-0.8	0.8	0.9	2.7	0.9	-0.2
Alzheimer’s Disease (including proxy)	2.3	3.3	5.7	-1.7	2.2	-2.4	-0.5	2.2	2.2	2.3	-0.8	0.1
Crohns Disease (2017)	7.9	17.2	50.1	1.6	-2.3	7.1	2.0	-6.9	-3.0	-4.2	4.2	0.2
Irritable Bowel Disease (IBD)	5.3	12.6	40.1	1.2	-2.2	6.3	1.0	-5.6	-2.7	-3.7	3.6	0.0
Ulcerative Colitis (UC)	1.7	3.3	12.7	0.0	-0.9	3.6	-0.1	-2.6	-1.4	-1.8	1.9	-0.1
Major Depression (MDD)	0.8	0.9	3.6	0.2	0.1	1.6	0.6	-1.9	0.2	0.2	1.3	0.3
Reaction Time	0.1	0.1	0.3	0.5	0.0	-0.0	-0.4	0.1	-0.1	-0.4	-0.2	-0.6
Verbal and Numeric Reasoning (VNR)	0.6	1.5	4.8	-1.3	2.2	-0.5	0.1	0.3	0.9	2.2	-0.3	0.8
Breast Cancer	0.8	2.0	6.2	0.0	-2.1	1.5	-0.4	-1.6	-1.1	-1.0	2.5	-0.9
Ovarian Cancer	0.1	0.2	0.7	0.2	0.8	0.1	0.0	-0.2	-0.3	-0.5	0.5	-0.5
Prostate Cancer	1.5	2.2	7.3	-0.4	0.1	-1.7	0.6	1.7	2.7	1.4	-1.8	0.7
Age at First Birth	0.5	0.7	4.1	0.5	-0.1	-0.9	-0.2	0.9	-0.5	0.4	-2.0	0.1
Bipolar Disorder (2011)	0.3	0.3	0.7	0.6	-0.5	0.4	0.6	-0.2	0.8	0.4	0.2	0.8
Body Mass Index (BMI) (2010)	0.5	0.8	2.5	1.0	0.3	0.3	1.0	-0.1	0.1	-0.9	-1.6	1.2
Coronary Artery Disease (CAD)	0.7	0.8	4.5	2.1	-0.9	0.1	0.7	-0.8	-0.6	-0.7	-0.1	0.3
Crohns Disease (2012)	6.1	9.8	30.8	1.7	-1.8	5.5	1.6	-5.4	-1.9	-2.9	2.6	0.9
Mean Putamen Volume	0.8	0.9	3.0	0.7	-1.2	1.7	0.5	-1.1	-0.5	-0.2	-0.6	1.0
Fasting Glucose	0.7	0.8	1.7	1.1	-0.3	-0.6	-1.3	1.1	-0.0	1.0	0.8	-1.1
HbA1C	0.4	0.5	2.2	-0.3	-0.9	-0.1	-0.6	-0.2	-0.3	-0.0	1.5	-0.6
HDL Cholesterol	0.5	0.9	3.5	0.7	0.7	0.3	1.9	-0.7	0.1	0.5	-0.5	1.6
LDL Cholesterol	0.7	1.1	6.0	0.5	-2.4	0.3	0.1	-1.0	-0.0	-0.6	1.3	-0.7
Lupus	0.4	0.7	1.9	-0.8	-0.9	0.1	1.4	-0.4	-0.6	0.5	-0.7	1.2
Neuroticism (2016)	1.3	1.8	4.4	-0.8	0.8	-1.9	-1.2	2.1	0.6	1.9	-1.1	-0.4
Primary Biliary Cirrhosis	2.1	3.0	7.5	1.4	-1.6	2.7	1.9	-2.2	-1.3	-1.6	0.3	1.2
Rheumatoid Arthritis	1.9	2.6	7.7	-0.8	-2.5	0.3	-1.5	-0.8	-0.6	-0.7	2.8	-2.1
Schizophrenia (2014)	0.9	2.1	5.1	2.3	1.4	0.1	2.0	-0.2	0.1	-1.5	-1.9	1.2
Triglycerides	0.7	1.2	3.2	-0.8	0.3	-1.1	-1.8	1.2	0.7	-0.3	0.8	-1.8
Type 2 Diabetes (T2D) (2012)	1.3	1.5	4.2	-1.0	0.9	0.6	0.7	-1.1	1.2	2.0	-0.4	2.0
Ulcerative Colitis	0.9	1.3	4.9	0.4	-1.3	2.2	-0.3	-1.7	-0.5	-0.9	1.1	0.2
Blood Eosinophil Count	18.8	144.5	368.6	2.9	-12.0	19.2	-1.5	-16.1	-13.5	-11.0	13.5	-5.7
Blood Platelet Count	3.4	39.1	151.3	-0.1	-4.6	12.3	2.7	-10.0	-5.6	-1.7	5.4	3.0
Blood Red Count	0.9	8.9	29.5	1.8	-1.5	5.0	1.5	-5.4	-1.9	-1.9	3.2	-0.2
Blood White Count	7.8	58.1	127.7	1.8	-10.0	11.3	-2.8	-8.9	-7.8	-7.5	8.2	-4.5
Heel T-Score	0.2	1.4	2.6	-0.0	-1.6	1.5	-1.3	-1.3	-0.8	0.6	1.6	-0.6
BMI	0.3	1.7	10.2	3.2	-0.6	0.6	0.6	0.1	-0.7	-1.1	-1.5	0.3
Height	0.4	6.8	16.1	-3.0	2.1	-4.0	-2.6	3.1	0.4	1.7	1.3	-3.3
Waist Hip Ratio (WHR)	0.5	2.3	9.2	-3.0	0.4	-0.8	-1.4	0.7	0.8	1.0	2.2	-1.4
Systolic Blood Pressure	0.7	3.5	6.2	1.4	-2.4	1.9	-0.5	-2.2	-2.5	-1.7	2.1	-1.2
Smoking Status	0.2	0.4	1.6	0.0	0.1	-1.1	0.2	0.8	-0.0	0.1	-1.3	0.5
Allergy or Eczema	5.7	15.1	43.8	0.9	-1.4	6.6	0.5	-5.5	-6.2	-2.0	4.0	-0.5
Cardiovascular Disease	1.4	4.5	12.8	-1.3	-0.1	0.2	-3.6	0.2	-3.0	-0.5	2.5	-3.2
Hypothyroidism (self reported)	0.4	0.9	2.1	0.8	0.3	1.2	1.5	-1.3	-0.4	-1.2	0.1	0.2
Respiratory disease	10.5	23.4	53.1	1.7	-1.6	7.3	-2.0	-6.1	-5.9	-4.1	6.6	-3.8
Type 2 Diabetes (T2D) (2018)	1.3	2.3	6.1	-1.3	-1.9	0.1	-2.1	0.7	-2.5	-0.4	1.3	-1.6
Lung FEV1/FVC ratio	0.9	4.7	13.3	0.3	1.0	-2.0	2.5	1.2	2.4	1.3	-3.6	3.0
Lung FVC	0.3	1.7	7.0	-0.8	-0.4	-1.7	-0.5	1.5	2.6	-0.6	0.9	-1.2
Neuroticism	0.3	0.8	1.5	0.7	1.0	-1.0	1.2	0.9	0.1	0.7	-1.2	1.0
Chronotype (morning person)	0.2	0.5	1.9	-1.1	0.7	0.1	-0.2	1.4	0.5	-0.3	0.2	-0.8
Hair Pigment	0.1	2.2	5.5	-0.9	1.3	-2.3	0.7	1.6	1.7	1.4	-1.6	1.0
Tanning	0.1	0.9	1.8	-0.1	-0.5	1.1	-0.1	-1.3	-0.5	-1.3	1.3	-0.9
Hand grip strength (left)	0.1	0.2	0.9	0.6	-0.4	-1.0	-0.2	0.3	-0.6	0.0	0.0	-0.6
Number of treatments/medications taken	0.7	1.3	5.1	-0.0	-0.5	1.8	-0.3	-0.8	-2.3	-1.1	1.1	-0.4
Average weekly spirits intake	0.3	0.3	1.1	-0.7	0.1	0.6	-1.0	0.2	-0.5	0.2	0.9	-0.5
Sensitivity / hurt feelings	2.0	3.4	10.1	-1.2	0.9	-2.5	-2.3	3.2	1.4	1.7	0.1	-1.4
Frequency of depressed mood in last 2 weeks	0.2	0.2	0.9	0.2	-0.0	0.4	0.4	-0.2	-0.7	-0.9	0.5	-0.5
Hearing difficulty/problems: Yes	0.6	1.0	2.8	-0.1	0.9	-1.4	0.4	1.0	1.7	0.6	-0.8	1.1
Relative age of first facial hair	0.5	1.0	2.3	0.2	-1.1	1.0	-1.0	-0.1	-1.5	-1.2	0.9	-1.3
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	1.4	0.6	0.3	-0.1	0.1	0.2	-1.2	-0.3	-0.5	0.1
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.2	-0.6	0.7	-0.6	-1.5	1.3	0.6	-0.1	0.1	-0.8
Ever had hysterectomy (womb removed)	1.6	1.8	4.5	1.0	1.4	-0.3	2.0	-0.7	-0.0	0.1	-2.1	2.0
Systolic blood pressure, automated reading	0.6	1.7	3.3	1.7	-1.8	0.9	-0.5	-1.4	-1.5	-1.2	0.9	-1.2
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	1.8	0.5	0.1	0.8	0.1	-0.7	-1.4	-0.2	-0.1	0.1
Angina	0.9	1.2	2.7	1.5	-1.6	0.3	-0.8	-0.6	-0.9	-1.2	0.6	-1.4
Medication for hormone replacement therapy	0.6	0.7	3.4	-1.9	-0.0	0.5	0.8	-0.1	0.0	0.7	-0.2	1.1
Vitamin and mineral supplements	0.7	0.9	3.0	-1.1	-0.7	0.5	-1.1	0.2	-0.2	-0.8	1.2	-1.7
Supplements: Zinc	1.1	1.2	4.2	-0.2	0.5	-1.3	0.1	1.4	0.9	2.1	-1.3	0.8
Medication: Co-codamol	1.4	1.6	5.5	-0.5	0.1	2.3	-0.6	-1.4	-1.4	-0.4	1.9	-0.6
Medication: Metformin	0.7	0.9	4.4	0.2	-2.1	-0.4	-0.8	1.0	-1.3	0.8	-0.1	-0.0
Diabetes (father)	0.2	0.2	0.6	-0.4	0.5	-0.4	0.4	0.2	-0.8	0.5	-0.2	0.3
Diabetes (mother)	0.1	0.1	0.4	-0.2	-0.6	0.2	-0.0	-0.1	-0.0	-0.4	0.5	-0.3
Severe depression (siblings)	0.8	0.9	3.9	0.8	-0.1	0.1	1.2	-0.3	-0.8	-0.1	-1.0	2.0
Pack years adult smoking proportion	0.5	0.8	3.3	0.2	-0.5	-0.9	-0.9	1.8	-0.4	1.0	-0.8	-0.3
Impedance of leg (right)	1.3	6.4	27.4	-2.6	-0.9	2.1	-1.4	-2.2	-0.6	-1.4	5.2	-3.0
Leg fat-free mass (left)	0.4	1.9	5.6	1.9	0.8	-1.8	0.5	1.8	-0.0	0.3	-2.4	0.4
Trunk fat percentage	0.7	2.7	6.4	0.8	-1.2	2.5	-0.9	-1.1	-2.2	-1.7	1.6	-1.9
Hand grip strength (right)	0.2	0.7	1.8	0.9	-0.9	-1.3	-0.3	0.5	-1.1	-0.4	-0.3	-0.9
Townsend deprivation index at recruitment	0.7	1.0	2.9	0.4	-1.0	1.5	-0.2	-1.0	-0.9	-1.7	0.7	-0.4
Current tobacco smoking	0.7	1.1	4.2	0.3	-0.2	-0.2	-1.1	0.7	-0.7	-2.0	0.3	-1.8
Average weekly fortified wine intake	1.2	1.4	3.4	-0.2	0.2	1.5	-1.0	-0.9	-1.8	-0.0	1.8	-1.3
Maternal smoking around birth	0.5	0.7	3.3	0.4	-1.8	1.1	0.7	-0.5	0.0	-0.8	0.5	-0.3
Fed-up feelings	0.4	0.8	3.3	-0.1	1.3	0.1	1.8	-0.4	0.7	0.3	-0.1	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	2.5	-1.6	-0.9	0.6	0.3	-0.4	-0.3	0.9	0.8	-0.1
Relative age voice broke	0.9	1.4	3.5	0.6	-1.9	0.8	-1.2	0.3	-0.9	-1.4	1.3	-1.4
Taking other prescription medications	2.1	3.2	7.4	-0.2	-1.2	2.7	-0.4	-1.4	-2.6	-2.3	2.2	-1.0
Age when periods started (menarche)	1.3	3.0	10.9	0.7	-1.2	1.8	-0.6	-1.1	-3.3	-2.0	1.7	-1.6
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.3	0.2	1.0	0.0	1.4	-0.5	0.0	0.0	-1.3	1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.2	0.8	-0.6	0.6	0.6	-0.7	-0.8	0.5	-0.7	1.1
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	3.7	-0.5	-0.0	0.8	-0.7	-0.5	-0.1	-1.5	1.9	-1.9
Qualifications: CSEs or equivalent	0.7	0.9	2.0	-1.4	0.1	-1.2	-0.8	1.2	1.0	-0.0	0.5	-1.0
Serious illness, injury or assault to yourself	0.7	0.8	3.1	0.6	-0.6	1.8	0.6	-1.4	-0.6	-0.6	-0.0	0.6
High blood pressure	0.4	1.1	2.9	-1.0	0.4	-1.3	-1.7	1.1	-1.0	0.9	0.3	-0.8
Hayfever, allergic rhinitis or eczema	4.1	8.9	28.9	1.5	-0.2	5.4	0.8	-4.2	-4.4	-1.4	3.1	-0.0
Multivitamins +/- minerals	1.1	1.4	4.5	0.6	0.7	-0.3	2.1	-0.6	1.1	0.5	-1.1	2.0
Stomach or abdominal pain in last month	0.1	0.2	0.8	-0.3	-0.9	-0.2	0.2	0.3	-0.6	-0.0	-0.1	-0.0
Supplements: Glucosamine	0.8	1.1	3.5	0.5	0.8	0.6	1.9	-1.2	0.7	-0.3	-0.7	1.5
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.6	1.0	-0.6	-0.0	-0.9	1.1	0.1	-1.3	-0.4	-1.2
Medication: Atenolol	0.3	0.4	1.0	-0.3	-1.0	0.7	0.2	-1.0	-0.6	-0.5	0.6	0.0
Medication: Levothyroxine sodium	1.1	1.9	4.7	2.2	0.5	-0.3	2.1	0.4	0.9	-0.3	-2.1	1.6
Sitting height	0.5	3.3	13.0	-0.5	2.1	-3.6	0.0	2.4	0.8	1.8	-1.6	-0.1
Chronic bronchitis/emphysema (father)	0.4	0.5	1.9	1.4	-0.7	-0.5	-0.3	0.6	-0.7	-0.7	-0.9	-0.2
High blood pressure (mother)	0.4	0.5	2.0	-0.9	-0.4	0.1	-0.7	-0.2	-1.4	0.9	0.2	-0.6
Body mass index (BMI)	0.3	1.4	6.8	2.6	-0.6	0.0	0.1	1.0	-0.5	-0.6	-2.0	0.4
Impedance of leg (left)	1.3	6.5	25.2	-3.1	-1.3	2.1	-1.8	-1.9	-0.8	-1.1	5.0	-3.0
Leg predicted mass (left)	0.3	1.7	5.1	1.9	0.8	-1.7	0.4	1.7	-0.0	0.2	-2.3	0.3
Trunk fat mass	0.2	1.0	2.6	0.7	-0.6	1.1	-0.9	0.0	-1.6	-1.0	0.7	-1.6
Waist circumference	0.2	0.6	2.5	0.5	0.2	-0.8	-1.0	1.6	-0.2	0.3	-0.5	-0.9
Number of incorrect matches in round	0.8	1.4	3.4	-0.2	0.6	-1.3	-1.7	1.9	1.1	0.6	0.5	-1.4
Past tobacco smoking	0.9	1.6	5.6	-0.3	-0.3	1.2	-1.7	-0.1	-0.2	-0.9	1.9	-2.4
Alcohol usually taken with meals	1.4	2.3	8.4	-0.5	2.9	-2.0	0.7	0.7	1.4	1.8	-1.2	0.6
Nervous feelings	0.6	1.1	2.9	0.3	0.5	-1.5	0.0	1.7	0.9	1.3	-1.4	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	2.2	0.4	0.1	-0.1	1.5	-0.3	0.7	-1.0	0.1	0.2
Hearing difficulty/problems with background noise	1.8	2.9	6.6	0.0	1.7	-2.0	1.5	1.0	2.6	1.9	-1.5	1.8
Hair/balding pattern: Pattern 2	1.5	1.9	7.2	-0.1	1.1	-2.1	0.3	0.7	2.7	1.7	-0.7	0.5
Had menopause	0.8	1.0	2.0	-1.2	0.3	-1.4	-1.3	1.2	1.2	0.8	0.0	-0.8
Had other major operations	1.1	1.3	3.3	1.8	1.2	0.2	1.7	-0.7	0.3	-0.3	-1.2	1.6
Forced vital capacity (FVC)	0.4	1.4	3.4	-1.0	1.7	-1.8	-0.1	1.0	1.8	0.4	0.7	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	6.1	0.6	-1.6	2.2	0.8	-2.1	-2.5	-0.1	0.4	1.1
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	3.5	-0.2	-0.8	0.8	-1.3	-0.4	-0.8	-0.3	1.9	-0.9
Qualifications: None of the above	1.2	2.6	6.9	0.9	-0.2	1.9	-0.2	-1.6	-1.2	-2.6	2.3	-1.5
Financial difficulties in last 2 years	0.7	1.0	2.6	0.2	-1.4	1.4	-1.0	-0.4	-0.0	0.0	1.6	-1.0
Mouth/teeth dental problems	0.8	1.3	3.2	0.8	-0.6	1.7	1.0	-1.8	-1.0	-1.2	0.9	0.6
Heart attack	0.6	0.8	3.5	0.0	-1.9	-0.7	-0.8	0.6	0.2	1.1	0.7	-0.4
Allergy	6.4	14.8	46.8	-3.0	0.5	-6.8	-0.7	5.3	5.4	2.4	-3.6	0.5
Pain all over the body in last month	1.0	1.1	5.6	-0.7	-2.4	0.9	-1.1	-0.4	-0.1	-0.3	0.9	-0.9
Diabetes (self-reported)	0.8	1.2	4.1	-0.9	-1.0	-0.1	-1.3	0.7	-2.0	-0.2	0.8	-1.3
Hayfever/allergic rhinitis (self-reported)	3.2	4.3	13.7	1.1	-1.4	3.7	0.7	-2.6	-2.7	-1.8	2.0	0.2
Medication: Ramipril	0.3	0.4	1.9	-0.5	-0.2	0.0	0.3	-0.3	0.2	1.4	0.3	1.3
Medication: Simvastatin	0.9	1.3	4.3	-1.3	-1.1	-0.2	-2.1	0.7	-1.1	-0.1	0.6	-1.6
Fluid intelligence score	0.9	1.9	10.3	-1.4	3.2	-0.5	0.3	0.1	0.3	1.9	-0.2	0.8
Illnesses of siblings	1.5	2.1	6.9	-2.3	1.1	0.4	-1.1	-0.3	0.3	-0.0	2.6	-2.0
Neuroticism score	0.8	1.7	3.4	-0.3	1.3	-1.8	0.9	1.9	1.2	1.5	-1.4	0.9
Weight	0.2	1.1	2.9	1.7	0.2	-1.2	-0.2	1.6	-0.4	0.0	-1.6	-0.4
Impedance of arm (right)	1.4	6.4	17.3	-1.1	-0.4	4.1	0.4	-3.9	-1.5	-1.6	4.2	-1.3
Arm fat percentage (right)	0.5	2.1	6.0	2.5	-1.4	2.2	0.2	-0.8	-1.6	-1.7	0.0	-0.4
Trunk fat-free mass	0.6	3.7	13.4	1.0	1.1	-3.7	-0.4	3.0	1.0	1.4	-2.4	-0.1
Hip circumference	0.2	0.9	3.5	1.9	0.2	-0.3	-0.1	1.1	-0.8	-0.3	-1.4	-0.3
Time employed in main current job	0.4	0.5	1.3	0.1	0.3	0.1	0.4	1.0	-0.4	0.8	-1.1	1.1
Alcohol intake versus 10 years previously	0.9	1.3	6.1	0.7	-2.5	0.5	-1.5	0.8	-0.8	-0.9	-0.1	-0.7
Father’s age at death	3.1	4.1	6.9	-2.3	1.5	-2.5	0.2	2.6	2.1	2.0	-2.4	1.2
Worrier / anxious feelings	1.0	1.9	6.0	-0.6	1.7	-2.4	-0.7	2.4	0.6	1.0	-0.0	-0.8
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.2	0.8	-0.6	0.9	-0.0	-0.7	-0.0	-0.1	1.1	-0.5
Falls in the last year	0.3	0.4	1.0	-0.5	1.0	0.8	0.7	-0.5	0.8	-0.1	-0.1	0.9
Hair/balding pattern: Pattern 3	0.7	1.1	4.1	-0.5	-0.5	0.6	-2.0	0.3	-1.7	-0.8	0.3	-1.1
Number of live births	0.2	0.2	0.9	-0.1	-0.3	-0.0	-0.2	0.5	0.4	-1.0	0.4	-0.6
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	7.3	-0.8	1.3	-1.9	0.8	1.0	2.7	0.8	-0.6	0.7
Pulse rate	0.6	1.1	2.6	1.3	-1.3	1.0	0.7	-0.8	-1.2	-1.6	0.2	-0.5
Happiness	0.4	0.5	1.8	0.1	-0.9	0.1	0.1	0.3	0.8	1.3	-0.3	0.9
Noisy workplace	0.7	0.8	3.0	-0.7	0.4	-1.4	-0.2	1.7	1.0	0.7	-0.6	-0.1
Qualifications: A levels/AS levels or equivalent	1.5	3.2	6.6	-0.5	1.6	-2.6	0.8	1.8	1.8	2.6	-1.8	1.6
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.5	0.9	-1.2	0.4	0.5	-0.5	0.8	0.3	0.0	0.3
Mouth/teeth dental problems: Dentures	0.3	0.5	4.2	-0.1	-2.0	0.3	-0.4	-0.2	-0.2	-0.1	0.0	-0.2
Asthma	6.5	12.7	36.4	2.7	-1.6	6.0	-0.7	-4.6	-4.2	-3.0	4.1	-2.0
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	5.6	0.6	2.4	-1.2	1.1	0.9	0.9	0.8	-2.2	1.1
Medication: Cholesterol lowering	1.3	2.0	5.5	-0.9	-1.7	-0.4	-2.3	1.3	-1.9	0.5	0.6	-1.5
Depression (self-reported)	0.1	0.2	0.5	-0.3	-0.2	-0.4	-0.0	0.7	-0.7	-0.1	-0.1	0.2
Medication: Lansoprazole	1.0	1.2	3.3	-1.6	0.2	-0.1	-1.8	0.5	0.3	1.0	1.4	-1.2
Prospective memory result	0.3	0.4	1.7	1.3	0.9	-0.2	0.6	0.3	0.4	-0.1	-0.6	0.5
Lung cancer (father)	0.9	1.1	1.9	1.3	1.3	-1.4	-0.1	0.9	1.2	-0.9	-1.0	-0.3
Illnesses of mother	0.8	0.9	2.4	1.1	0.7	0.6	1.6	-0.8	1.0	-0.5	-0.2	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	6.7	-0.8	0.6	-1.9	0.3	1.4	2.6	0.3	-0.2	-0.0
Pulse wave Arterial Stiffness index	0.3	0.4	1.6	-0.2	-0.8	0.2	1.3	-0.2	0.3	-0.1	-0.2	1.0
Impedance of arm (left)	1.1	5.2	13.5	-1.7	-0.1	3.5	0.8	-3.7	-1.7	-1.4	3.4	-0.8
Arm fat mass (right)	0.3	1.2	5.4	2.3	-1.0	0.6	-0.3	0.5	-1.0	-1.2	-0.8	-0.6
Trunk predicted mass	0.6	3.6	13.1	1.0	1.0	-3.6	-0.5	3.0	0.9	1.4	-2.3	-0.3
Standing height	0.3	2.7	6.7	-2.0	1.6	-2.6	-1.1	1.6	0.1	1.1	1.0	-2.2
Length of working week for main job	0.5	0.6	2.5	-1.2	0.4	-0.4	0.0	-0.0	1.6	0.8	0.2	0.1
Exposure to tobacco smoke at home	0.1	0.1	0.3	0.2	-0.3	0.5	-0.1	-0.2	-0.2	-0.5	0.3	-0.1
Breastfed as a baby	4.2	5.2	9.5	1.1	2.8	-2.9	1.8	2.0	2.6	1.5	-3.1	2.0
Tense / ‘highly strung’	1.2	2.0	4.9	-0.6	1.9	-2.1	0.6	2.2	1.1	1.6	-1.0	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	3.5	-0.3	0.9	-1.5	-0.1	1.9	0.8	1.7	-1.7	0.9
Hair/balding pattern: Pattern 4	0.1	0.3	0.7	0.6	-0.7	-0.8	0.2	0.5	0.5	-0.4	-0.8	-0.4
Birth weight of first child	0.6	1.1	4.6	0.1	2.1	-1.1	-0.8	1.5	0.5	0.6	-0.5	-0.8
Peak expiratory flow (PEF)	2.0	4.7	14.6	0.0	1.4	-1.6	2.5	0.3	3.8	1.6	-2.0	3.1
Pulse wave reflection index	0.5	0.6	1.2	-0.7	0.7	-0.6	0.8	0.9	1.0	0.3	-0.4	1.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.7	-0.0	-0.7	1.3	0.0	-1.0	-0.3	-1.1	0.9	-0.7
Loud music exposure frequency	0.8	0.9	2.3	1.4	-1.5	0.8	-0.9	-0.7	-0.2	-0.8	0.8	-0.8
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.1	-0.1	0.3	-0.7	0.3	0.5	1.4	0.9	-0.8	0.9
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	3.7	-0.3	1.3	-0.7	-1.7	1.9	0.5	0.1	-0.2	-1.1
Blood clot in the leg (DVT)	0.8	1.1	4.1	0.3	2.0	-1.0	0.0	1.3	-0.1	1.5	-0.7	0.3
Medication: Paracetamol	0.8	1.3	3.3	0.1	-0.3	1.7	-0.4	-1.5	-1.4	-0.6	1.8	-1.1
Headache pain in last month	0.4	0.7	1.8	-1.4	-0.3	0.6	-0.5	-0.4	-0.1	0.2	1.3	-1.3
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	4.8	1.3	1.4	0.1	2.2	-0.6	2.2	0.6	-1.2	1.8
Glaucoma (self-reported)	1.0	1.2	2.5	-1.6	1.6	-0.6	-1.0	0.3	0.7	0.1	1.4	-1.3
Gout (self-reported)	0.3	0.4	0.9	0.6	0.9	-0.5	-0.0	0.8	0.0	-0.9	0.1	-0.9
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.7	1.6	-0.0	0.7	1.6	-0.9	-0.4	-1.0	-0.2	0.8
Medication: Amlodipine	0.6	0.8	2.9	0.5	-0.9	-0.1	0.3	-0.6	-1.7	-1.7	-0.3	-0.6
Medication: Ventolin 100micrograms inhaler	5.4	6.9	18.8	1.3	-2.3	4.3	-1.1	-3.4	-3.6	-1.0	3.0	-1.1
Birth weight	1.2	2.5	9.4	-0.3	0.8	-0.5	-3.1	1.5	-0.8	-0.1	1.0	-2.9
Chronic bronchitis/emphysema (mother)	1.2	1.4	3.8	1.0	-1.9	1.1	-0.2	-0.7	-0.5	-1.9	1.1	-1.1
High blood pressure (siblings)	1.2	1.7	5.6	1.0	-1.6	-0.9	0.7	0.6	0.6	0.7	-2.4	2.0
Forced vital capacity (FVC), Best measure	0.2	0.8	2.5	-0.9	0.5	-1.2	0.0	0.7	1.6	-0.0	0.9	-0.8
Body fat percentage	0.5	2.1	5.1	1.2	-1.4	2.3	-0.8	-0.7	-1.8	-1.5	1.2	-1.5
Leg fat percentage (right)	0.3	0.9	1.5	1.1	-1.1	1.2	-0.7	-0.0	-0.8	-0.9	0.8	-1.2
Arm fat-free mass (right)	0.5	2.8	9.3	0.5	0.5	-3.0	-1.1	3.0	0.3	1.0	-1.9	-0.7
Exposure to tobacco smoke outside home	0.8	1.1	4.6	2.1	-0.8	-0.8	0.7	0.5	0.5	-1.5	-0.9	0.1
Comparative body size at age 10	0.4	1.1	3.0	1.7	-1.6	0.7	1.3	-0.6	0.8	-0.7	-0.4	0.6
Number of full brothers	0.8	1.0	2.6	-0.8	1.6	-0.4	-1.0	0.8	1.3	1.1	1.0	-0.5
Worry too long after embarrassment	1.4	2.3	5.6	-0.4	0.8	-2.4	1.1	2.3	1.0	1.3	-1.7	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.1	2.6	-1.6	1.2	-0.2	-1.4	0.9	0.3	0.5	1.3	-1.0
Wheeze or whistling in the chest in last year	1.7	3.1	6.9	-0.7	-2.3	1.4	-2.2	-0.4	-1.2	-0.6	2.6	-2.5
Number of children fathered	0.4	0.4	1.3	-1.1	-0.6	-0.3	-1.0	0.8	0.6	0.0	-0.3	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.6	6.7	0.2	0.9	-2.6	1.1	2.0	0.8	1.4	-2.4	1.5
Age at first live birth	0.2	0.3	1.1	-0.1	0.7	-0.9	-0.2	0.2	0.5	1.1	0.2	-0.4
Pulse wave peak to peak time	0.4	0.5	1.6	0.1	1.0	-0.4	-1.2	0.2	-0.2	0.1	0.2	-1.2
Health satisfaction	1.1	1.4	3.1	-0.9	-1.2	-1.6	-0.6	1.8	1.4	1.5	-0.5	0.3
Shortness of breath walking on level ground	0.8	1.0	4.9	-0.7	-2.2	1.4	0.6	-0.7	-0.0	0.1	0.5	0.7
Qualifications: College or University degree	0.7	2.3	6.5	0.8	2.6	-0.5	2.1	-0.8	-0.4	1.5	-1.0	2.2
Eye problems/disorders: None of the above	0.2	0.3	1.0	0.3	-1.0	-0.2	0.4	0.5	0.2	-0.3	-0.3	0.7
Mouth/teeth dental problems: Loose teeth	0.5	0.5	2.1	-0.6	-0.8	0.9	-0.5	0.3	-1.5	-0.1	-0.5	0.5
Emphysema/chronic bronchitis	1.7	1.9	4.5	-1.8	1.3	-1.0	-2.1	1.8	0.1	0.6	0.7	-1.5
Medication for pain relief, constipation, heartburn	0.4	0.7	1.9	0.3	0.1	-1.3	0.1	0.8	1.4	-1.0	-1.1	-0.0
Neck or shoulder pain in last month	1.0	1.4	6.6	-1.8	2.6	-0.6	1.0	0.5	0.6	0.8	-0.2	0.5
Medication: Blood pressure	0.9	1.6	6.2	-0.5	-1.5	0.4	-1.4	-0.0	-2.5	-1.0	0.8	-1.2
Angina (self-reported)	0.8	1.0	2.2	1.4	-1.5	0.1	-0.7	-0.3	-0.7	-1.2	0.5	-1.5
Migraine (self-reported)	0.3	0.4	2.0	-0.2	-1.4	-0.1	-0.6	0.4	0.4	0.9	0.4	0.5
Medication: Ibuprofen	1.8	2.2	5.6	1.3	2.4	-0.8	2.0	0.4	0.8	-0.0	-2.3	1.3
Medication: Allopurinol	0.7	0.9	1.9	-0.2	1.4	-1.2	-0.3	1.3	1.0	-0.3	0.6	-1.1
Medication: Omeprazole	2.7	3.2	8.8	-0.8	-1.7	3.0	-0.8	-2.2	-1.8	-0.9	2.5	-0.8
Medication: Seretide 50 evohaler	0.4	0.5	2.4	0.9	0.6	1.5	-0.1	-0.4	-0.5	-0.4	0.6	-0.2
Mean time to correctly identify matches	0.1	0.1	0.4	-0.1	0.2	-0.2	-0.6	0.4	-0.1	0.1	-0.1	-0.6
Heart disease (mother)	0.6	0.7	1.4	-0.8	-1.2	-0.8	-0.8	0.7	1.1	0.7	-0.1	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.6	-0.1	0.5	-0.6	-0.5	0.7	-0.6	0.7	-0.2	-0.1
Whole body fat mass	0.2	0.8	1.8	1.3	-0.7	0.5	-0.9	0.7	-1.3	-0.7	-0.1	-1.3
Leg fat mass (right)	0.2	0.6	1.8	1.4	-0.6	0.3	-0.6	0.7	-0.6	-0.8	-0.1	-1.1
Arm predicted mass (right)	0.6	3.0	10.5	0.7	0.5	-3.2	-1.0	3.0	0.4	0.9	-2.0	-0.6
Pulse rate, automated reading	1.9	6.3	13.2	1.6	-1.7	3.3	0.2	-2.6	-3.5	-3.6	2.1	-1.9
Alcohol intake frequency.	0.1	0.3	0.9	-0.2	-0.8	0.3	0.6	0.3	0.5	0.3	-0.7	1.0
Comparative height size at age 10	0.4	2.2	6.7	-2.0	-0.6	-0.8	-1.8	0.2	-1.1	-0.3	1.7	-2.6
Number of full sisters	1.1	1.3	3.4	1.9	0.1	-0.7	1.4	0.3	1.2	-0.0	-1.6	1.4
Suffer from ‘nerves’	0.8	1.2	4.2	-0.4	0.9	-2.1	-0.5	1.7	1.1	0.7	-0.5	-0.3
Overall health rating	0.4	1.0	2.3	0.2	-1.5	0.3	-0.9	0.8	-1.5	-1.1	0.6	-1.0
Chest pain or discomfort	0.4	0.5	1.5	0.7	0.5	0.3	-0.8	-0.6	-0.1	-0.1	1.2	-1.2
Had major operations	0.7	0.8	3.4	1.0	-0.2	0.6	-0.3	0.3	-1.1	1.8	-0.3	0.8
Age at last live birth	0.2	0.2	0.8	0.4	0.1	-0.1	-0.9	0.1	-0.4	0.5	0.4	-0.7
Family relationship satisfaction	0.1	0.1	0.4	0.4	-0.2	0.4	-0.3	0.0	0.6	-0.3	0.2	-0.4
Leg pain on walking	1.4	1.7	4.6	0.2	0.1	-1.4	0.7	2.0	1.5	0.5	-2.1	1.3
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.1	0.4	-0.8	1.1	-0.6	-0.0	0.5	0.3	-0.6	0.2
Commuting to job workplace: Car/motor vehicle	1.6	1.8	4.8	-1.6	0.1	-1.4	-1.6	1.5	1.3	2.2	-0.1	-0.6
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	3.2	-0.7	1.6	-1.8	0.7	0.7	0.7	0.9	-1.3	0.7
Medication: Aspirin	0.4	0.5	2.4	0.2	-0.4	-0.3	0.3	0.4	-0.6	1.5	-0.2	0.9
Supplements: Vitamin C	1.1	1.3	3.2	0.9	1.4	-1.0	0.4	0.8	-0.2	1.2	-1.6	1.8
Knee pain experienced in last month	0.7	1.0	2.8	1.6	-0.5	-0.6	0.3	0.8	1.7	-1.5	-0.1	-0.7
Hypertension (Self-reported)	0.3	0.9	3.0	-0.9	0.3	-0.9	-1.7	0.9	-1.2	0.6	0.4	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	3.5	-1.9	-0.7	0.9	-1.5	0.0	-0.7	1.1	1.5	-0.4
Illnesses of father: Heart disease	2.4	3.3	8.9	1.0	-2.4	2.6	1.0	-3.0	-1.8	-1.1	1.3	0.2
Illnesses of siblings: Diabetes	1.2	1.5	4.5	1.8	-1.3	-0.6	1.6	0.0	-0.2	-0.6	-2.1	1.1
Smoking status: Previous	1.6	2.4	9.7	-0.0	0.1	-0.8	2.3	-0.5	0.3	1.4	-1.9	3.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	2.2	-0.1	0.7	-1.5	0.2	0.8	0.3	0.6	-0.1	-0.4
Whole body fat-free mass	0.5	2.8	8.6	1.4	0.8	-2.9	-0.1	2.6	0.5	1.0	-2.5	0.1
Leg fat-free mass (right)	0.4	2.2	7.5	1.7	0.9	-1.9	0.5	1.9	-0.1	0.6	-2.7	0.6
Arm fat percentage (left)	0.5	1.8	4.3	2.1	-1.4	2.0	0.2	-0.7	-1.6	-1.6	-0.2	-0.3
Average weekly red wine intake	1.5	2.2	6.8	-1.0	2.6	-0.6	1.2	0.3	0.2	1.9	-1.6	1.9
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.7	0.4	-0.2	1.6	0.4	-0.9	-1.2	-1.2	0.3	0.7
Mood swings	0.3	0.5	1.3	0.4	0.7	-0.9	-0.6	1.0	-0.5	0.2	-0.2	-1.1
Loneliness, isolation	0.8	1.1	3.3	-0.4	-1.8	0.6	-1.4	0.1	-0.7	0.1	1.3	-1.5
Long-standing illness, disability or infirmity	0.1	0.2	0.7	0.4	-0.1	-0.5	-0.1	0.5	-0.6	-0.8	0.2	-0.3
Ever had bowel cancer screening	0.5	0.5	1.0	-0.3	0.8	1.0	-0.9	-0.2	-0.8	0.7	0.9	-0.5
Diabetes diagnosed by doctor	0.7	1.1	4.3	-0.8	-1.3	-0.1	-1.2	0.7	-2.1	-0.2	0.9	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	2.8	1.2	-1.4	1.2	-0.3	-1.0	-1.7	-0.4	0.3	-0.2
Friendships satisfaction	0.5	0.7	1.8	0.1	-0.0	0.6	1.3	-0.8	1.0	0.5	0.1	1.3
Qualifications: nursing, teaching	0.7	1.1	2.7	0.9	1.0	-0.9	1.3	0.0	1.6	0.6	-1.3	0.9
Commuting to job workplace: Walk	0.6	0.6	1.5	0.3	-1.1	0.7	1.2	-1.0	0.5	-0.3	0.7	0.6
Eye problems/disorders: Cataract	0.7	0.8	1.6	-0.2	-1.1	0.7	-0.8	-0.9	-1.0	-0.9	0.5	-1.3
Mouth/teeth dental problems: Mouth ulcers	1.6	2.5	8.8	1.0	3.0	-2.6	0.7	1.4	1.4	0.6	-1.2	-0.1
Medication for cholesterol	0.3	0.5	1.3	0.8	-0.4	0.3	1.0	-1.1	0.1	-1.0	-0.0	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.1	2.4	7.1	-0.2	0.0	-1.9	1.6	1.3	1.2	1.0	-2.7	2.1
Back pain experienced in last month	0.6	0.9	2.2	0.4	0.1	-1.2	-0.3	1.5	1.3	1.1	-1.1	-0.2
Mineral and other dietary supplements	0.5	0.7	1.9	0.2	-1.4	-0.2	-1.2	1.1	-0.9	-0.4	-0.1	-0.7
Breast cancer (self-reported)	0.3	0.3	0.9	0.4	-0.1	0.2	-0.9	-0.2	-0.8	-0.1	0.5	-1.0
Asthma (self-reported)	6.5	12.9	37.1	2.5	-1.2	6.1	-0.6	-4.7	-4.2	-3.0	4.2	-2.0
Osteoporosis (self-reported)	0.3	0.4	2.3	-0.2	-1.5	-0.7	-0.6	0.5	-0.5	0.0	0.1	-0.4
Osteoarthritis (self-reported)	0.4	0.5	2.2	-0.1	0.6	0.8	0.7	-0.7	1.5	-0.2	0.6	0.2
Medication: Aspirin	0.2	0.3	0.9	0.6	-0.6	-0.4	0.1	0.5	-0.7	0.9	-0.2	0.4
Medication: Gliclazide	1.0	1.2	2.5	-1.3	-1.3	-1.3	-1.1	1.2	-0.3	1.6	-0.3	-0.4
Illnesses of father: None of the above (group 1)	2.1	2.6	6.5	0.1	1.5	-2.2	0.3	2.5	2.5	-0.1	-1.7	0.5
Smoking status: Current	0.7	1.1	3.6	0.4	-0.3	-0.1	-1.2	0.7	-0.8	-1.7	0.5	-1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	4.8	-0.8	1.0	-0.9	0.2	0.7	2.2	0.1	-0.0	0.4
Whole body water mass	0.5	2.8	8.9	1.3	0.9	-3.0	-0.2	2.7	0.6	1.0	-2.4	0.0
Leg predicted mass (right)	0.4	2.2	7.3	1.6	0.8	-2.0	0.4	2.0	-0.1	0.6	-2.7	0.6
Arm fat mass (left)	0.3	1.1	4.3	2.1	-1.0	0.6	-0.0	0.4	-1.1	-1.2	-0.9	-0.4
Number of self-reported non-cancer illnesses	2.1	3.7	10.6	0.3	-0.5	2.3	-1.7	-1.2	-3.3	-1.1	2.7	-2.0
Average weekly champagne plus white wine intake	0.6	0.8	1.7	0.1	-0.2	-1.3	0.6	1.3	1.2	0.8	-1.0	0.5
Miserableness	0.8	1.3	4.7	-0.4	1.2	-1.3	-0.1	1.1	1.1	2.2	-1.0	0.3
Guilty feelings	1.8	2.7	6.0	-0.5	0.7	-1.8	0.3	2.3	0.9	2.4	-2.3	1.6
Wears glasses or contact lenses	1.1	1.2	3.6	-0.2	0.0	-1.6	-1.0	1.9	0.9	1.7	-0.3	-0.2
Ever taken oral contraceptive pill	0.7	0.8	2.1	1.1	-0.6	1.2	0.8	-1.0	-0.7	-1.4	-0.2	0.2
Hearing aid user	1.1	1.2	5.8	2.4	0.2	-0.6	0.7	0.2	0.1	-0.6	-1.9	0.0
Mother’s age at death	3.3	4.1	9.7	-1.5	1.9	-3.1	0.1	2.0	1.4	2.6	-2.5	1.4
Financial situation satisfaction	0.8	1.0	3.0	0.4	-0.3	-1.7	0.0	1.6	1.4	1.1	-0.7	0.4
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.7	0.1	1.0	-0.1	0.9	-0.3	1.3	0.1	-0.7	0.5
Commuting to job workplace: Public transport	0.2	0.2	0.6	-0.6	0.2	0.1	-0.8	0.6	-0.3	0.6	0.0	0.2
Eye problems/disorders: Glaucoma	0.8	0.9	2.9	-1.7	1.0	-0.7	-1.0	1.1	0.7	0.8	0.6	-0.6
Medication: Blood pressure	0.3	0.5	1.3	-0.2	0.8	-0.7	-0.4	1.2	0.5	1.0	-0.7	0.3
Pain type(s) experienced in last month: Hip pain	1.0	1.3	4.2	0.7	0.4	-1.4	1.7	0.4	1.0	-0.7	-2.0	0.7
Supplements: Fish oil (including cod liver oil)	0.7	0.9	3.2	-1.2	1.8	-0.6	0.6	-0.2	1.4	0.6	0.4	0.3
High cholesterol (Self-reported)	1.5	2.6	11.7	-0.6	-1.7	-0.5	-3.4	1.6	-0.9	0.3	0.7	-2.2
Medication: Bendroflumethiazide	0.4	0.7	1.6	0.7	0.6	0.6	0.5	-0.7	-1.0	-0.4	-1.2	1.0
Medication: Paracetamol	0.8	1.2	3.2	0.3	-0.0	1.0	-0.7	-0.8	-1.1	-1.0	1.8	-1.8
Medication: Lisinopril	1.3	1.7	5.1	-0.8	-0.0	-1.1	-2.2	1.5	-0.4	0.1	0.8	-2.3
Medication: Atorvastatin	0.8	1.0	5.3	0.6	-1.2	0.9	-0.3	-0.4	-2.3	-0.0	0.9	-0.4
Illnesses of father: High blood pressure	0.3	0.4	0.9	-0.7	-0.1	0.9	-0.0	-1.0	-0.9	0.4	0.4	0.4
Alcohol drinker status: Never	0.2	0.3	0.8	-0.9	-0.9	0.2	-0.2	0.2	-0.3	0.6	-0.1	0.6
Ever smoked	1.1	1.9	6.4	0.4	0.4	-1.5	1.5	0.5	0.7	0.2	-2.5	2.2
Basal metabolic rate	0.4	2.2	6.0	1.6	0.7	-2.5	-0.1	2.3	0.3	0.6	-2.3	-0.0
Leg fat percentage (left)	0.2	0.9	1.8	0.8	-1.4	1.0	-1.0	0.3	-0.9	-0.8	0.5	-1.2
Arm fat-free mass (left)	0.6	2.9	8.8	1.4	0.7	-3.0	-1.0	3.0	0.4	0.9	-1.9	-0.7
Number of operations (self-reported)	0.3	0.5	1.5	1.2	0.6	0.5	0.4	-0.1	-0.6	0.6	-0.7	1.0
Average weekly beer plus cider intake	0.9	1.2	4.0	-0.6	-2.0	-0.3	-1.0	0.4	-0.3	-1.6	0.9	-1.4
Irritability	1.3	2.2	5.7	0.7	2.4	-0.9	2.1	0.3	0.1	1.0	-1.6	2.3
Risk taking	2.3	3.4	7.2	-0.3	2.7	-2.7	-0.0	2.4	2.0	2.0	-1.5	0.1
Ever had prostate specific antigen (PSA) test	1.7	2.0	6.7	0.4	0.3	0.3	2.6	-1.2	-0.0	0.8	-1.6	2.5
Fractured/broken bones in last 5 years	0.4	0.5	1.9	-0.7	-0.5	0.5	-0.8	-0.2	0.1	-0.2	0.9	-1.4
Age started oral contraceptive pill	0.6	0.7	2.3	-0.1	1.1	-1.5	-0.5	0.6	0.4	1.3	-0.0	-0.5
Diastolic blood pressure, automated reading	0.7	2.1	4.4	0.5	-1.2	1.4	-0.6	-1.4	-2.1	-1.9	1.6	-1.5
Ever depressed for a whole week	0.2	0.3	1.5	-0.1	-0.1	-0.4	-0.6	0.5	1.2	0.3	0.3	0.2
Unable to work because of sickness or disability	0.2	0.3	0.6	-0.8	-0.2	0.4	-0.6	0.2	-0.1	-0.5	0.7	-0.8
Commuting to job workplace: Cycle	0.8	1.0	2.8	0.9	0.4	1.0	-0.8	-0.7	-1.7	-0.9	1.1	-1.0
Myopia	0.5	0.7	1.9	-0.2	-0.4	-1.1	-0.0	0.1	1.2	-0.6	1.1	-1.4
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.5	0.5	-0.1	1.2	1.6	-1.0	0.9	-0.6	-0.4	1.0
Cholesterol lowering medication	0.4	0.6	1.8	-0.1	-1.2	0.5	-1.3	0.2	-0.6	-0.5	0.6	-0.8
Medication: Omeprazole (e.g. Zanprol)	3.0	3.6	10.0	-0.7	-1.3	3.2	-0.5	-2.7	-1.8	-0.9	2.8	-0.9
Pain experienced in last month	0.2	0.3	2.1	-0.2	1.4	-0.0	-0.5	-0.1	0.2	0.6	0.4	-0.1
Supplements: Calcium	1.0	1.1	1.9	-1.0	0.5	-1.3	-0.5	1.3	0.9	1.3	-1.4	1.0
Basal cell carcinoma (self-reported)	0.6	0.7	1.6	1.0	0.1	0.7	0.7	-1.0	0.0	1.2	-0.1	1.3
Heart attack/myocardial infarction (self-reported)	0.7	0.9	4.5	-0.1	-2.1	-0.5	-0.9	0.5	0.2	1.1	1.0	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.2	0.3	1.5	-0.8	0.0	1.1	-0.3	1.0	-0.4	0.1
Heart disease (siblings)	0.5	0.6	2.2	0.8	-0.6	-0.4	0.5	1.0	0.2	-0.0	-1.5	0.7
Alcohol drinker status: Previous	0.8	0.9	2.9	-1.7	0.6	-0.6	0.3	0.9	1.2	1.0	-0.8	0.6
Pack years of smoking	0.8	1.1	4.5	-0.0	-0.2	-1.3	-1.0	2.1	-0.2	1.4	-1.0	-0.2
Impedance of whole body	1.4	7.0	23.9	-2.6	-0.8	3.3	-0.8	-3.1	-1.6	-1.4	4.9	-2.4
Leg fat mass (left)	0.2	0.6	1.4	1.2	-0.7	0.1	-0.8	1.0	-0.7	-0.6	-0.3	-1.0
Arm predicted mass (left)	0.5	2.7	8.7	1.2	0.6	-2.8	-1.2	3.0	0.2	0.8	-1.8	-0.8