TWAS hub - DCLRE1B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0710	0.0260	2.5e-04	0.044	0.036	0.027	0.035	0.028	4.4e-06	3.1e-05	2.8e-04	3.5e-05	2.3e-04
2	GTEx	Breast Mammary Tissue	0.1850	0.0780	4.3e-04	0.017	NA	0.004	NA	0.032	4.5e-02	NA	1.9e-01	NA	9.1e-03
3	GTEx	Cells Transformed fibroblasts	0.0640	0.0300	2.4e-03	0.038	NA	-0.003	NA	0.018	7.8e-04	NA	6.9e-01	NA	1.5e-02
4	GTEx	Esophagus Mucosa	0.1180	0.0450	2.1e-03	0.003	NA	0.005	NA	0.003	1.9e-01	NA	1.3e-01	NA	2.0e-01
5	ROSMAP	Brain Pre-frontal Cortex	0.0781	0.0345	1.4e-04	0.042	0.031	0.052	0.039	0.045	3.5e-06	5.6e-05	2.6e-07	8.1e-06	1.6e-06
6	YFS	Blood	0.2343	0.0294	0.0e+00	0.346	0.312	0.339	0.341	0.343	1.8e-118	1.1e-104	1.5e-115	1.6e-116	1.6e-117
7	TCGA	Breast Invasive Carcinoma	0.0161	0.0101	3.6e-03	-0.001	0.009	0.007	NA	0.000	7.3e-01	5.2e-03	8.9e-03	NA	4.1e-01
8	TCGA	Esophageal Carcinoma	0.1270	0.0660	5.0e-03	0.021	0.078	0.032	NA	0.038	7.2e-02	1.8e-03	3.4e-02	NA	2.3e-02
9	TCGA	Glioblastoma Multiforme	0.1960	0.0920	8.2e-03	-0.008	0.036	0.010	NA	0.004	6.4e-01	3.0e-02	1.5e-01	NA	2.3e-01
10	TCGA	Thyroid Carcinoma	0.0600	0.0280	4.5e-05	0.042	0.040	0.043	NA	0.039	5.2e-05	8.7e-05	4.3e-05	NA	1.0e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Hypothyroidism (self reported)	79.6	182.8	361.0	-5.0	-15.8	-8.4	2.1	-17.4	5.5	-17.3	-14.8	-16.3	-19.0
Rheumatoid Arthritis	77.7	106.9	216.1	-4.3	-10.3	-8.6	2.4	-13.1	3.3	-12.5	-11.1	-13.7	-14.7
Hypothyroidism/myxoedema (self-reported)	64.4	125.7	252.8	-3.6	-13.3	-6.9	2.0	-14.2	5.2	-14.6	-12.6	-12.7	-15.9
Medication: Levothyroxine sodium	47.0	79.6	161.3	-2.9	-10.5	-5.4	1.9	-11.6	3.8	-11.4	-10.0	-10.2	-12.7
Taking other prescription medications	11.6	17.9	33.5	-2.6	-5.7	-3.7	0.6	-5.1	0.2	-4.6	-4.3	-5.2	-5.8
Long-standing illness, disability or infirmity	10.8	16.5	33.2	-2.5	-5.2	-3.3	-0.5	-5.0	0.2	-4.5	-4.1	-5.8	-5.0
Number of treatments/medications taken	7.3	13.2	27.2	-3.9	-4.7	-3.0	0.5	-4.4	-1.9	-3.0	-2.7	-5.2	-4.4
Other serious medical condition/disability diagnosed by doctor	7.2	9.4	17.9	0.5	-2.9	-2.8	0.7	-3.2	2.1	-3.8	-3.5	-4.2	-4.2
Breast Cancer	6.5	15.6	34.5	3.1	3.4	4.0	0.5	5.9	0.5	4.1	3.6	4.8	5.5
Lupus	6.2	9.4	19.8	-0.8	-3.6	-0.8	0.4	-4.3	1.6	-4.5	-2.7	-3.5	-4.3
Crohns Disease (2017)	5.7	12.6	32.7	2.4	2.4	2.9	-0.9	5.7	0.3	4.1	3.6	3.8	5.3
Serious illness, injury or assault to yourself	5.0	6.0	15.1	-3.0	-2.5	-0.9	-0.9	-2.9	-2.6	-0.4	-2.1	-3.9	-2.9
Medication: Cholesterol lowering	4.8	7.5	15.1	-3.2	-3.9	-2.0	0.1	-3.0	-1.4	-2.2	-1.8	-3.8	-3.4
Worry too long after embarrassment	4.7	7.8	17.0	0.7	3.0	3.0	0.2	3.1	-1.0	3.5	2.8	4.1	3.5
Diabetes (self-reported)	4.5	6.9	12.2	-3.2	-3.5	-1.5	-0.1	-2.9	-0.4	-2.8	-2.4	-3.3	-3.3
Overall health rating	4.4	9.4	21.7	-3.4	-4.1	-2.3	-0.2	-3.8	-1.7	-1.9	-2.3	-4.7	-3.5
Pulse wave Arterial Stiffness index	4.1	4.8	9.6	2.5	2.1	1.6	-0.5	3.1	-0.6	2.2	2.5	2.3	2.9
Medication for cholesterol, blood pressure or diabetes	4.0	6.7	15.4	3.3	3.9	1.4	-0.9	2.5	1.0	2.1	1.2	3.8	3.0
Blood White Count	3.9	28.9	60.2	0.9	4.6	4.1	2.8	6.6	-2.3	5.7	7.0	7.3	7.8
Chest pain or discomfort	3.9	5.6	11.3	-2.7	-2.2	-1.7	2.1	-2.8	0.0	-2.7	-1.2	-3.0	-3.4
Heart attack/myocardial infarction (self-reported)	3.9	5.1	10.0	-2.5	-2.5	-2.0	0.6	-2.6	-1.1	-1.7	-2.0	-3.2	-3.0
Bipolar Disorder (2011)	3.8	3.6	7.3	-1.6	-2.7	-2.2	1.5	-2.2	-0.2	-1.6	-2.0	-1.8	-2.1
Mouth/teeth dental problems: Bleeding gums	3.7	4.7	12.1	-3.5	-2.8	-1.8	-0.7	-2.6	-3.2	0.4	-0.6	-1.9	-1.5
Alcohol drinker status: Never	3.7	4.4	9.8	1.1	-3.1	-0.7	0.0	-1.9	1.5	-2.6	-2.5	-2.9	-2.3
Crohns Disease (2012)	3.6	5.7	15.9	1.1	1.4	2.1	-1.3	4.0	-0.0	2.7	2.9	2.1	3.5
Diabetes diagnosed by doctor	3.6	5.9	10.8	-2.8	-3.3	-1.0	-0.2	-2.7	-0.4	-2.5	-2.2	-3.2	-3.2
Pulse wave peak to peak time	3.5	4.1	7.9	-2.1	-1.9	-1.2	0.4	-2.8	0.7	-2.1	-2.5	-2.2	-2.7
Heart attack	3.4	4.3	7.9	-2.5	-2.4	-1.9	0.4	-2.3	-1.2	-1.5	-1.8	-2.8	-2.8
Commuting to job workplace: Car/motor vehicle	3.4	3.9	9.7	2.0	1.1	2.0	0.9	2.5	0.1	2.1	1.5	3.1	2.6
Wears glasses or contact lenses	3.2	3.7	8.2	0.9	-1.7	-2.9	-1.8	-0.5	2.1	-2.4	-2.3	-2.1	-1.5
Age when periods started (menarche)	3.1	7.4	16.4	1.3	2.4	1.6	-0.5	4.1	-0.4	2.8	3.1	4.0	3.7
Alcohol intake frequency.	3.1	7.1	13.7	0.0	-3.5	-2.4	1.1	-3.0	1.0	-2.4	-3.7	-3.5	-3.3
Ever smoked	3.1	5.4	9.3	2.0	2.5	1.8	2.6	2.9	1.3	1.3	3.0	2.5	2.7
Myopia	3.1	4.5	14.7	0.1	-2.2	-1.3	0.4	-2.3	0.6	-2.2	-2.1	-3.8	-2.9
Frequency of tiredness / lethargy in last 2 weeks	2.9	4.8	12.5	-3.4	-1.5	-0.5	0.4	-3.2	-2.0	-0.9	-0.6	-3.5	-2.3
Reaction Time	2.8	5.3	14.1	0.7	2.7	3.8	-0.4	1.8	-0.4	2.5	3.0	2.2	2.6
Allergy or Eczema	2.8	7.4	14.1	1.0	3.0	2.2	-1.0	3.8	-0.8	3.2	3.0	3.6	3.4
Number of incorrect matches in round	2.8	4.6	9.8	-0.9	-3.0	-2.0	-0.3	-2.8	0.5	-1.4	-3.1	-2.1	-2.7
Hayfever/allergic rhinitis (self-reported)	2.8	3.7	9.9	1.6	0.9	3.1	1.3	2.4	0.9	1.4	1.3	2.8	2.1
Birth weight	2.8	6.2	16.2	1.8	3.0	4.0	-0.3	2.6	0.6	1.8	2.5	3.0	2.8
Angina	2.6	3.4	8.6	0.4	-2.0	0.0	0.8	-1.8	0.9	-2.1	-2.7	-2.2	-2.9
Past tobacco smoking	2.6	4.8	8.8	-1.5	-2.1	-1.9	-1.9	-2.6	-0.6	-1.8	-3.0	-2.7	-2.6
Ever unenthusiastic/disinterested for a whole week	2.6	3.1	9.1	-0.9	-1.9	-0.6	3.0	-2.6	0.5	-1.6	-1.1	-2.1	-1.6
Birth weight of first child	2.6	4.8	9.2	1.6	3.0	2.1	0.9	3.0	1.1	1.6	1.8	2.9	2.6
Pulse wave reflection index	2.6	3.2	5.3	2.2	2.0	1.7	-0.6	2.2	-0.0	1.4	1.9	1.9	2.3
Angina (self-reported)	2.6	3.4	8.5	0.5	-1.9	0.2	0.8	-1.8	1.1	-2.2	-2.6	-2.3	-2.9
Medication: Aspirin	2.6	3.4	7.3	-0.4	-2.4	-1.2	0.7	-1.9	0.8	-2.7	-1.8	-2.2	-2.5
Hayfever, allergic rhinitis or eczema	2.5	5.5	11.6	1.2	2.6	2.3	0.4	3.2	-0.0	2.1	2.6	3.4	2.8
Illness, injury, bereavement, stress in last 2 years	2.5	3.0	11.8	3.4	1.6	-0.8	0.2	1.7	2.8	-1.1	-0.1	1.4	1.1
Number of self-reported non-cancer illnesses	2.5	4.3	12.4	-2.1	-3.5	-0.5	0.8	-2.1	-1.2	-1.9	-0.8	-3.0	-2.4
Commuting to job workplace: Public transport	2.4	2.9	8.6	-1.2	-1.0	-2.2	-0.7	-1.8	-0.1	-1.8	-1.5	-2.9	-2.0
Alcohol usually taken with meals	2.3	3.8	9.9	-1.4	-3.1	-1.5	-0.6	-2.2	-0.5	-2.0	-2.0	-1.8	-2.5
Medication: Metformin	2.2	3.1	7.4	-2.6	-2.7	-1.2	-0.0	-2.2	-0.6	-1.2	-1.7	-1.6	-1.9
Basal cell carcinoma (self-reported)	2.2	2.6	4.6	0.0	1.1	0.7	-2.1	1.7	-0.7	1.9	2.0	2.1	1.9
Diabetes (mother)	2.1	2.6	5.4	0.6	1.4	1.8	-0.0	1.8	-1.1	2.3	1.9	1.4	2.3
Tinnitus: Yes, but not now, but have in the past	2.1	2.3	3.2	1.4	-1.8	-1.6	0.7	-1.5	1.8	-1.7	-1.7	-1.6	-0.9
Mean time to correctly identify matches	2.1	4.1	8.5	1.4	2.8	2.9	0.2	1.8	0.3	1.7	2.8	2.1	2.2
Medication: Aspirin	2.1	2.8	5.5	-0.9	-2.2	-1.2	0.9	-1.8	0.2	-2.3	-1.5	-1.9	-2.3
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	4.5	-2.0	-1.6	-1.1	-0.4	-1.9	-0.8	-0.8	-2.1	-1.4	-1.5
Headache pain in last month	2.0	3.4	6.6	-1.8	-2.1	-2.3	1.4	-2.1	0.0	-1.4	-1.5	-2.6	-2.0
Medication: Gliclazide	2.0	2.3	5.5	-1.2	-0.8	-1.3	-0.5	-2.0	0.3	-2.4	-0.7	-2.3	-1.9
Townsend deprivation index at recruitment	1.9	2.6	9.2	-2.2	0.3	-0.1	-0.9	0.4	-3.0	2.5	1.6	0.6	1.5
Number of live births	1.9	2.7	7.7	0.1	1.4	0.6	-0.1	2.1	-1.3	2.4	1.3	2.8	1.8
Health satisfaction	1.9	2.4	5.1	-0.5	-2.1	-0.2	1.4	-2.2	-0.1	-1.0	-1.6	-2.2	-2.0
Coronary Artery Disease (CAD)	1.8	2.2	5.3	0.0	-1.1	-2.3	0.2	-1.5	-0.3	-1.5	-1.7	-1.9	-2.1
Average weekly spirits intake	1.8	2.3	6.5	-0.6	2.5	1.9	1.6	0.6	-0.4	1.2	2.4	1.0	1.0
Average weekly fortified wine intake	1.8	2.1	3.8	1.6	0.9	1.9	-1.5	1.9	0.6	1.1	1.1	1.8	1.5
Supplements: Glucosamine	1.8	2.3	7.6	0.1	1.7	-0.5	-2.8	1.4	-0.7	1.1	2.0	0.8	2.1
Length of working week for main job	1.8	2.0	5.1	-0.6	1.6	2.0	1.2	1.0	-0.9	1.4	2.2	1.0	1.2
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	4.5	1.0	-0.2	-1.3	0.2	-1.7	1.0	-1.8	-1.6	-2.1	-2.0
Illnesses of father: Heart disease	1.8	2.5	6.3	-1.9	-2.5	-1.0	1.2	-2.0	-1.4	-1.1	-1.1	-1.2	-1.6
Mother’s age at death	1.8	2.3	4.8	0.3	1.4	1.0	-0.3	2.2	-0.3	1.6	2.1	2.0	1.9
Relative age of first facial hair	1.7	3.5	6.9	-0.3	1.9	2.0	0.1	1.9	-1.3	2.1	2.4	2.3	2.6
Medication: Amlodipine	1.7	2.3	5.8	-0.4	-2.4	-0.7	-0.6	-2.0	-0.2	-1.2	-1.1	-2.4	-2.1
High blood pressure (siblings)	1.7	2.5	7.6	-0.0	1.3	1.7	2.7	0.8	-0.5	0.5	2.5	1.3	2.0
Medication: Blood pressure	1.7	3.0	7.7	-2.8	-2.5	-0.4	1.3	-1.6	-1.3	-0.9	-0.0	-2.5	-1.7
Ever had prostate specific antigen (PSA) test	1.7	1.9	4.1	-1.9	-0.3	-1.1	-0.6	-2.0	-0.1	-1.7	-0.9	-1.7	-1.9
Alcohol drinker status: Previous	1.7	1.9	7.2	-1.9	-0.9	-1.8	0.5	-0.7	-1.0	-0.9	-0.4	-2.7	-1.2
Shortness of breath walking on level ground	1.6	1.8	5.0	-0.6	-2.2	-1.1	-0.6	-1.4	-0.6	-0.6	-2.2	-1.5	-1.3
Smoking status: Previous	1.6	2.3	4.9	1.1	1.8	1.1	0.9	1.8	0.4	1.5	1.9	2.2	1.6
Medication: Atorvastatin	1.6	2.0	5.9	-0.7	-1.3	-0.4	-0.1	-1.4	0.8	-2.4	-1.2	-1.7	-2.2
Medication: Omeprazole (e.g. Zanprol)	1.6	1.9	7.7	-2.3	-0.8	-1.3	1.0	-0.6	-2.8	1.2	-1.0	-0.3	-0.4
Bipolar Disorder or Schizophrenia	1.5	3.6	9.5	-1.2	-3.1	-1.8	1.2	-2.0	0.8	-1.8	-2.4	-1.7	-2.0
Irritable Bowel Disease (IBD)	1.5	3.5	8.2	1.8	1.1	2.0	0.4	2.7	0.4	2.1	1.8	1.6	2.9
Fasting Glucose	1.5	1.8	4.5	1.4	1.4	1.1	-0.1	1.5	2.1	-0.6	1.7	1.2	1.2
Medication: Atenolol	1.5	1.9	5.5	-1.4	-2.3	-0.9	0.2	-1.3	-0.8	-1.0	-0.9	-2.0	-1.8
Father’s age at death	1.5	2.0	6.7	0.8	1.5	-0.2	-0.7	2.6	0.4	1.0	1.8	1.9	1.5
Medication for pain relief, constipation, heartburn	1.5	2.6	6.2	2.5	1.6	1.1	-2.3	1.4	2.2	-0.2	0.5	1.4	1.1
Type 2 Diabetes (T2D) (2018)	1.4	2.7	7.3	-2.6	-1.7	-0.0	0.4	-1.5	-0.4	-1.7	-0.6	-2.7	-2.0
Ever had hysterectomy (womb removed)	1.4	1.5	2.4	1.5	1.4	1.4	0.2	1.4	0.0	1.3	1.2	1.4	1.6
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.2	6.2	-2.2	-0.8	-0.2	0.8	-2.0	-0.9	-0.9	-1.1	-2.5	-1.8
Illnesses of siblings	1.4	1.9	5.2	1.9	-1.0	-1.1	-0.6	-0.3	1.9	-1.0	-2.3	-0.6	-1.7
Chronic bronchitis/emphysema (mother)	1.4	1.6	5.9	-2.4	-1.2	-0.5	2.1	-1.0	-1.7	-0.1	0.4	-0.3	-0.2
Medication: Omeprazole	1.4	1.7	7.0	-2.0	-0.9	-0.9	1.2	-0.8	-2.6	1.1	-1.0	-0.6	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.7	7.1	-1.4	-1.0	0.2	0.5	-1.0	-2.7	1.1	-1.3	-1.5	-0.7
Smoking Status	1.3	3.0	8.7	0.5	2.0	1.6	2.9	1.6	0.4	0.7	2.6	1.4	1.7
Current tobacco smoking	1.3	2.1	8.5	1.1	1.3	1.4	2.9	0.9	-0.2	0.7	1.7	1.0	1.7
Pain all over the body in last month	1.3	1.4	6.6	-2.6	0.2	-0.3	0.5	-0.5	-1.9	0.2	1.2	-1.1	0.2
Depression (self-reported)	1.3	1.6	4.4	1.2	-1.6	-0.1	2.1	-1.3	1.4	-1.4	-0.9	-0.8	-0.5
Heart disease (mother)	1.3	1.6	4.7	-0.2	-2.2	-1.2	-0.6	-0.9	-0.5	-1.2	-1.7	-1.7	-1.3
Loneliness, isolation	1.3	1.7	6.7	-0.7	-0.8	0.2	2.6	-1.3	0.6	-1.9	-1.1	-1.2	-1.2
Qualifications: nursing, teaching	1.3	2.0	4.8	0.8	-1.4	-0.5	-0.8	-1.4	1.0	-2.2	-1.4	-1.6	-2.0
Bipolar Disorder (2018)	1.2	1.9	5.0	-0.1	-1.9	-0.3	0.4	-1.9	1.0	-1.5	-2.2	-1.5	-1.0
Sensitivity / hurt feelings	1.2	2.1	6.3	0.3	2.5	1.6	-0.4	1.2	-0.5	1.8	1.1	1.8	1.6
Ever used hormone-replacement therapy (HRT)	1.2	1.5	5.4	1.2	2.3	0.3	-0.6	1.3	-0.4	0.9	1.6	1.0	1.2
Mouth/teeth dental problems	1.2	1.8	5.1	1.5	1.1	1.6	1.0	1.2	1.7	-0.3	0.7	2.3	1.0
Allergy	1.2	2.8	6.9	0.1	-2.0	-1.5	-0.3	-2.0	0.7	-1.6	-2.2	-2.6	-1.8
Hair/balding pattern: Pattern 3	1.2	1.8	6.9	2.6	2.1	-0.2	-1.9	1.2	1.1	0.2	0.4	-0.1	0.7
Illnesses of mother	1.2	1.5	4.8	-1.9	1.0	0.3	-1.4	-1.4	-2.2	1.2	0.3	-0.2	-0.2
Number of children fathered	1.2	1.4	5.3	2.3	0.5	1.1	1.8	-0.5	1.8	-0.6	-0.3	-0.4	-0.1
Medication: Ibuprofen	1.2	1.5	2.9	-1.6	-1.2	-1.5	1.7	-1.1	-0.6	-0.6	-0.2	-1.7	-1.0
Smoking status: Current	1.2	1.9	7.0	0.8	1.3	1.6	2.6	0.8	-0.4	0.5	1.8	0.8	1.5
Ever taken oral contraceptive pill	1.2	1.3	4.0	-2.0	-1.4	-1.0	-0.1	-0.8	-0.2	-0.8	-1.4	-1.1	-1.3
Risk taking	1.2	1.8	4.7	-1.8	-1.3	-2.2	-0.8	-1.0	-0.3	-1.2	-1.2	-1.3	-1.2
Depression (Nagel 2018)	1.1	1.6	6.1	-2.5	-0.1	0.3	0.7	-1.7	-1.9	-0.1	-0.1	-1.5	-0.7
Intelligence (Savage-Jansen 2018)	1.1	3.5	8.7	2.1	2.4	1.0	0.0	3.0	-0.5	2.0	1.7	1.7	2.2
Chronotype (morning person)	1.1	2.5	5.9	-2.0	-2.2	-1.3	-1.7	-1.3	0.0	-1.2	-0.3	-2.4	-1.7
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	3.6	-0.5	1.6	1.0	-0.1	0.8	-1.4	1.9	0.8	1.1	0.8
Noisy workplace	1.1	1.3	3.0	-1.5	-1.3	-1.7	-1.3	-0.1	-1.4	0.7	-0.6	-1.0	-0.4
Emphysema/chronic bronchitis	1.1	1.2	2.9	-0.6	-1.2	-0.4	-1.0	-1.7	-0.7	-0.6	-1.5	-1.3	-1.2
Average weekly red wine intake	1.1	1.6	4.0	-1.5	1.0	-1.3	-2.0	-0.7	0.0	-1.4	-0.1	-1.5	-1.4
Medication: Bendroflumethiazide	1.1	1.6	5.5	-2.1	0.4	-0.1	0.6	0.1	-2.3	1.0	1.6	1.1	0.8
Major Depression (MDD)	1.0	1.2	4.3	0.2	-2.1	-0.6	0.5	-1.3	0.6	-0.8	-1.4	-0.8	-1.2
LDL Cholesterol	1.0	1.6	4.5	-2.0	-0.8	-1.2	-2.1	-1.1	-1.4	0.6	-0.4	-1.3	0.1
Cardiovascular Disease	1.0	3.2	9.4	-3.1	-2.8	-0.1	2.1	-0.9	-1.8	-0.5	-0.5	-2.0	-1.6
Tense / ‘highly strung’	1.0	1.6	7.8	-2.8	-1.4	0.2	0.5	-1.3	-1.7	-0.1	0.2	-0.7	-0.8
Medication: Paracetamol	1.0	1.7	5.1	-2.3	-1.0	-0.9	2.0	-1.0	-1.7	0.5	-0.4	-0.9	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.0	4.9	-0.3	-0.3	-0.9	-1.2	-2.2	0.1	-1.9	-1.5	-1.9	-1.8
Miserableness	1.0	1.7	4.5	-1.9	-1.2	0.7	2.1	-1.4	-1.8	0.3	0.7	-0.8	-0.6
Average weekly beer plus cider intake	1.0	1.5	3.7	1.5	0.4	0.8	1.9	1.3	1.8	0.4	0.5	1.1	1.3
Diastolic blood pressure, automated reading	1.0	3.0	8.9	-0.9	1.8	0.2	-3.0	1.2	-1.5	1.8	2.3	0.8	2.1
Schizophrenia (2018)	0.9	1.9	6.1	-1.4	-2.5	-2.1	0.7	-1.0	0.2	-1.1	-1.2	-0.9	-1.4
HbA1C	0.9	1.0	3.9	-0.9	-2.0	-1.3	-0.9	-1.1	-0.4	-0.1	-0.6	-0.8	-0.8
Maternal smoking around birth	0.9	1.3	4.4	-0.1	1.8	0.5	-0.3	0.7	-1.3	2.1	0.6	0.6	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.3	-1.8	0.4	1.1	1.3	-1.0	-1.8	1.1	0.2	-0.6	0.1
Impedance of leg (left)	0.9	4.5	11.4	-0.7	3.4	2.2	0.0	2.1	-0.9	1.7	2.8	2.3	2.6
Medication: Ramipril	0.9	1.2	5.1	-1.7	-0.5	0.8	1.2	-0.7	-2.2	0.9	0.4	-0.5	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	6.2	-1.2	-0.7	-0.8	2.5	-0.4	-0.5	-0.4	0.3	-1.2	-0.3
Exposure to tobacco smoke at home	0.9	1.0	2.9	-0.2	0.9	0.2	-1.3	1.3	-0.1	1.2	0.4	1.1	1.7
Ever highly irritable/argumentative for 2 days	0.9	1.0	2.7	-1.6	0.6	0.9	0.0	-1.2	-1.6	0.0	0.9	-1.2	-0.3
Loud music exposure frequency	0.9	0.9	3.6	-1.4	-0.5	-0.0	0.8	-1.2	0.1	-1.1	0.1	-1.9	-0.6
Migraine (self-reported)	0.9	1.2	3.7	1.1	-0.8	-0.5	1.9	-0.4	1.8	-1.5	0.2	-0.4	-0.2
Medication: Seretide 50 evohaler	0.9	1.0	4.0	-2.0	0.2	1.6	0.3	-0.7	-1.1	-0.4	1.3	-0.3	-0.3
Number of full sisters	0.9	1.1	2.8	-0.6	-0.8	-1.6	-1.7	-0.7	-0.8	0.4	-1.3	-0.8	-1.0
Illnesses of siblings: Diabetes	0.9	1.2	7.3	-2.7	-1.0	-0.4	1.1	-0.8	-0.4	-1.1	0.0	-0.3	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	4.9	-0.3	2.2	0.7	0.4	0.8	-0.5	0.7	1.1	0.3	1.0
Back pain experienced in last month	0.9	1.2	3.3	-1.8	-1.1	-0.2	0.5	-1.4	-1.4	0.1	-0.4	-1.6	-1.0
Unable to work because of sickness or disability	0.9	1.2	3.1	-1.2	-1.6	-0.3	0.4	-1.5	-0.9	-0.8	-0.6	-1.8	-0.8
Pain experienced in last month	0.9	1.6	7.5	1.6	-0.1	0.2	-0.1	-0.1	2.7	-2.0	-0.7	-0.3	-1.2
Prostate Cancer	0.8	1.1	3.0	-1.3	1.2	-0.3	-1.3	-1.0	-1.7	0.7	0.0	-1.2	-0.8
Lung FVC	0.8	4.2	10.1	-1.1	-0.8	-2.0	-2.0	-2.4	-0.6	-2.1	-1.7	-3.2	-2.9
Impedance of leg (right)	0.8	3.9	8.5	-0.3	2.9	2.0	0.6	2.2	-0.5	1.3	2.7	2.3	2.5
Chronic bronchitis/emphysema (father)	0.8	0.9	1.9	0.7	1.2	0.7	-0.2	1.2	-0.8	1.4	1.2	0.1	0.8
Qualifications: None of the above	0.8	1.7	5.4	-1.2	0.8	0.9	-1.1	0.7	-2.3	2.1	1.4	0.1	1.0
Ever had bowel cancer screening	0.8	0.9	2.6	-1.6	-0.9	-1.4	0.9	-0.4	-0.6	-0.6	0.2	-0.6	-1.4
Alzheimer’s Disease (in father)	0.7	0.7	3.4	-0.5	-0.5	-0.5	-1.1	-0.8	0.4	-0.3	-1.9	-0.7	-0.8
Verbal and Numeric Reasoning (VNR)	0.7	1.6	6.3	2.5	1.0	1.0	0.1	1.6	0.1	1.3	0.6	1.2	1.2
Ovarian Cancer	0.7	1.0	2.6	-1.2	0.9	0.9	0.4	-0.5	-1.6	0.8	1.6	0.3	0.9
Age at First Birth	0.7	1.0	1.8	0.2	-1.3	-0.9	-0.3	-1.2	0.8	-1.4	-1.1	-1.2	-1.0
Neuroticism	0.7	1.7	4.3	-1.8	1.6	1.1	-1.3	0.1	-2.1	1.5	1.1	-0.4	0.4
Hand grip strength (left)	0.7	2.0	5.7	2.0	2.4	0.9	0.9	1.5	1.6	0.3	1.1	0.9	1.2
Diabetes (father)	0.7	0.9	2.8	-0.8	-1.7	0.4	0.8	-1.1	-0.4	-0.6	-0.9	-1.2	-0.7
Severe depression (siblings)	0.7	0.7	2.0	0.9	-0.9	-1.0	1.4	-0.3	0.1	-0.2	-1.2	-1.1	-0.4
Medication: Simvastatin	0.7	1.0	4.7	-1.6	-0.8	-0.8	0.4	0.1	-2.2	0.9	-0.1	-0.3	-0.5
Alcohol intake versus 10 years previously	0.7	1.1	3.0	0.9	-0.4	-0.1	1.1	-1.2	1.7	-1.3	-0.7	-0.9	-0.9
Number of full brothers	0.7	0.9	2.0	-0.7	1.4	-1.2	-0.1	0.3	-1.2	0.5	1.2	0.5	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.3	1.4	-0.2	1.5	1.5	0.6	0.7	0.7	-0.2	0.5	1.1
Commuting to job workplace: Walk	0.7	0.7	3.0	1.7	0.3	-0.4	0.3	0.0	1.3	-0.6	-0.5	-1.2	-0.6
Average weekly champagne plus white wine intake	0.7	0.9	3.8	-1.0	0.7	1.1	-0.7	0.7	-0.8	0.6	2.0	0.6	0.6
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.5	0.0	0.7	0.9	0.9	0.7	-0.5	1.6	-0.3	1.4	1.0
Medication: Paracetamol	0.7	1.1	4.5	-2.1	-0.4	-0.6	0.7	-0.4	-1.9	1.1	0.1	-0.7	-0.2
Number of operations (self-reported)	0.7	1.0	2.2	-0.2	0.8	0.9	-0.0	1.4	-1.3	1.5	1.1	0.4	1.2
Age started oral contraceptive pill	0.7	0.9	4.1	0.9	-0.9	-0.4	-2.0	-0.3	0.0	-1.0	-0.8	-0.3	-1.1
Commuting to job workplace: Cycle	0.7	0.9	2.8	1.0	1.1	1.7	-0.8	1.1	1.0	0.4	0.4	0.5	0.8
Supplements: Calcium	0.7	0.8	3.1	-0.5	-1.0	-1.8	-1.0	-0.3	-1.0	-0.2	-0.7	-0.6	-0.1
Heart disease (siblings)	0.7	0.8	3.2	-0.8	-0.9	-0.8	0.1	-1.8	-0.6	-0.3	-0.9	-1.0	-0.7
Impedance of whole body	0.7	3.4	9.2	-0.9	3.0	2.0	-0.7	1.6	-1.1	1.5	2.3	1.9	2.1
Heel T-Score	0.6	4.6	20.4	-0.7	-1.1	-4.5	1.3	-0.9	1.3	-1.1	-3.7	1.5	-1.5
BMI	0.6	3.4	10.8	-0.9	-3.3	-2.2	0.4	-1.1	-0.3	-0.2	-3.2	-1.5	-1.8
Respiratory disease	0.6	1.3	3.6	-1.1	-0.7	0.2	1.6	-1.9	-0.4	-1.1	-0.1	-1.5	-1.2
Supplements: Zinc	0.6	0.6	2.9	-0.7	0.3	0.0	1.7	0.3	0.6	-0.3	1.3	-0.1	0.6
Relative age voice broke	0.6	1.0	1.8	-0.1	1.0	0.3	-0.0	1.3	-0.7	1.3	1.3	1.0	1.3
Qualifications: CSEs or equivalent	0.6	0.8	4.2	-0.2	-1.5	-0.2	-2.0	-0.3	0.1	0.7	-0.9	0.4	-0.0
High blood pressure (mother)	0.6	0.8	2.0	1.3	-0.9	0.2	1.1	1.3	1.4	-0.6	0.1	-0.2	0.4
Lung cancer (father)	0.6	0.7	1.4	0.5	0.9	0.8	-0.8	0.9	0.2	1.2	1.1	0.6	0.6
Exposure to tobacco smoke outside home	0.6	0.8	3.8	-0.2	1.3	1.3	0.6	-0.0	-0.0	0.1	1.9	-0.1	0.6
Knee pain experienced in last month	0.6	0.9	2.0	-0.2	-1.4	-1.3	-0.8	-0.5	-1.4	0.8	-1.1	-0.7	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	6.6	-0.3	1.4	2.6	0.8	0.6	-0.7	0.8	1.0	0.4	0.6
Mood swings	0.6	1.0	3.7	-1.9	-0.6	-0.0	0.9	-1.4	-1.4	0.1	0.3	-1.0	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	3.9	0.0	0.5	0.4	0.1	2.0	-0.5	1.7	0.6	0.1	1.1
Medication for cholesterol	0.6	0.9	2.8	1.2	1.7	1.2	-0.1	0.2	1.1	0.5	0.7	0.6	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.5	1.2	-1.6	-0.8	0.0	-0.5	0.4	-1.0	-0.5	-0.6	-0.8
Osteoporosis (self-reported)	0.6	0.8	2.4	0.5	1.6	0.4	-0.5	1.0	-0.7	0.6	1.2	0.8	1.0
High cholesterol (Self-reported)	0.6	1.1	3.7	-1.9	-1.7	-0.2	0.2	-0.1	-1.9	0.5	-0.2	-0.5	-0.6
Illnesses of father: High blood pressure	0.6	0.8	2.2	-0.3	-0.6	1.4	-1.1	0.7	-0.7	0.4	1.5	-0.1	0.8
Irritability	0.6	1.1	5.1	-1.5	-0.7	-0.3	2.3	-0.9	-1.2	-0.4	0.4	-0.5	-0.3
Depressed Affect (Nagel 2018)	0.5	1.1	2.7	-1.6	-0.2	1.1	1.2	-1.3	-1.1	-0.2	0.2	-1.4	-0.9
Neuroticism (Nagel 2018)	0.5	1.1	2.6	-1.6	0.8	1.5	0.8	-0.2	-1.6	1.1	0.8	0.2	0.2
Ulcerative Colitis	0.5	0.7	3.2	-0.6	0.1	0.1	-0.6	-1.3	-0.9	0.3	-0.2	-1.8	-0.7
Blood Eosinophil Count	0.5	3.6	7.5	1.8	1.0	1.7	1.0	2.7	1.6	0.6	1.5	2.7	2.7
Frequency of depressed mood in last 2 weeks	0.5	0.8	1.8	-1.1	0.2	1.3	1.1	-1.1	-0.8	-0.4	0.5	-0.9	-0.4
Pack years adult smoking proportion	0.5	0.8	1.5	-0.9	-1.2	-1.2	-0.0	-1.0	-1.0	-0.6	-0.5	-1.1	-0.7
Fed-up feelings	0.5	0.9	3.0	-1.5	0.8	1.7	1.3	-0.4	-0.6	0.3	1.1	-0.5	0.2
Stomach or abdominal pain in last month	0.5	0.6	1.4	-1.2	-0.1	-0.9	0.3	-0.8	-0.5	-0.1	-0.8	-1.1	-0.8
Body mass index (BMI)	0.5	1.9	6.0	-0.5	-2.4	-1.4	0.9	-1.5	-0.3	-0.3	-2.1	-0.8	-1.6
Hearing difficulty/problems with background noise	0.5	0.9	2.7	0.7	0.9	1.6	0.6	0.6	-0.3	0.7	1.3	0.0	1.3
Asthma	0.5	0.9	2.4	-0.8	0.4	-0.6	1.3	-1.2	0.9	-1.5	0.2	-0.8	-1.0
Peak expiratory flow (PEF)	0.5	1.2	2.8	1.5	1.4	0.6	-1.0	1.0	1.1	0.5	-0.8	1.7	0.6
Comparative body size at age 10	0.5	1.5	5.6	1.0	-0.7	0.6	2.4	-0.7	1.4	-1.2	-1.0	-1.1	-1.2
Wheeze or whistling in the chest in last year	0.5	0.9	1.8	-0.6	1.1	0.9	1.3	0.7	-0.8	0.8	1.3	0.4	0.9
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.4	0.4	-1.1	-0.5	1.5	-0.7	0.4	-1.1	-0.2	-0.4	-0.5
Neck or shoulder pain in last month	0.5	0.8	5.3	-0.2	-0.6	0.3	2.3	-0.0	-0.9	0.2	0.2	-0.9	0.3
Pulse rate, automated reading	0.5	1.5	8.3	-2.2	-0.5	-0.1	-0.3	-0.8	-2.9	1.0	-0.0	0.4	-0.1
Had major operations	0.5	0.6	1.8	-1.1	-0.3	-0.9	0.6	-0.4	-0.3	-0.8	-0.1	-1.3	-0.9
Leg pain on walking	0.5	0.6	1.2	-0.5	-1.0	-1.0	-0.5	-0.4	-1.1	0.6	-0.7	-1.0	-0.4
Hypertension (Self-reported)	0.5	1.4	3.5	-1.8	-0.9	0.9	1.9	-0.1	-1.7	-0.0	1.6	-0.6	-0.1
Handedness (chirality/laterality): Left-handed	0.5	0.6	3.9	0.4	0.9	0.8	2.0	0.3	-0.1	0.7	0.4	0.2	0.4
Mineral and other dietary supplements	0.5	0.7	3.1	0.6	-0.4	1.1	1.8	0.1	0.9	-0.2	-0.7	-0.1	-0.7
Asthma (self-reported)	0.5	1.0	2.9	-0.6	0.2	-0.7	1.2	-1.4	0.9	-1.7	0.0	-1.0	-1.2
Medication: Lisinopril	0.5	0.7	1.4	-0.7	-1.2	0.1	-0.2	0.8	-1.1	1.1	0.9	0.8	0.8
Vascular/heart problems diagnosed by doctor	0.5	1.3	2.7	1.4	1.6	0.0	-1.6	0.7	1.1	0.8	-0.5	1.5	1.2
Worry (Nagel 2018)	0.4	0.8	3.2	-1.8	0.3	1.4	-0.4	-0.7	-1.2	0.2	0.3	0.0	-0.3
Alzheimer’s Disease (in mother)	0.4	0.5	1.6	-1.0	-0.2	0.4	-0.2	-0.8	-0.8	-0.4	0.1	-1.3	-0.9
Type 2 Diabetes (T2D) (2012)	0.4	0.5	2.5	0.9	-0.6	0.5	0.3	0.5	1.6	-0.5	0.0	-0.2	0.1
Blood Platelet Count	0.4	4.3	18.1	-3.3	0.1	0.3	2.6	-1.3	-4.3	0.8	2.3	-0.3	0.0
Vitamin and mineral supplements	0.4	0.6	1.7	-0.9	0.6	-0.4	0.9	-0.9	-1.3	-0.1	0.3	-0.9	-0.8
High blood pressure	0.4	1.2	2.9	-1.6	-1.1	0.6	1.7	-0.1	-1.6	-0.0	1.6	-0.5	-0.2
Multivitamins +/- minerals	0.4	0.5	2.1	0.1	-0.9	0.7	0.5	0.3	1.4	-0.6	-0.0	0.5	0.2
Nervous feelings	0.4	0.7	1.9	-1.4	-0.6	1.3	0.1	-1.0	-0.6	-0.8	0.4	-0.8	-0.8
Hair/balding pattern: Pattern 2	0.4	0.6	1.4	-1.2	0.9	0.2	0.2	0.2	-0.9	1.1	0.6	0.6	0.7
Impedance of arm (right)	0.4	1.8	5.4	-0.1	2.3	1.6	-0.4	1.3	-0.3	0.9	1.7	1.4	1.4
Time employed in main current job	0.4	0.5	1.3	1.1	0.5	0.2	-0.3	0.8	-0.8	1.0	0.4	0.6	0.7
Falls in the last year	0.4	0.5	2.5	-1.0	0.7	0.4	0.7	-0.0	-1.6	0.4	0.0	-0.5	-0.2
Happiness	0.4	0.5	2.2	-0.0	-0.1	0.7	1.5	-1.0	-0.3	-0.2	-0.7	-0.0	-0.5
Prospective memory result	0.4	0.5	2.0	-0.1	-1.3	0.2	1.4	0.7	0.4	-0.1	-0.6	0.6	0.2
Impedance of arm (left)	0.4	1.9	4.8	-0.8	2.2	1.6	-0.9	1.2	-0.8	1.1	1.4	1.5	1.5
Breastfed as a baby	0.4	0.5	1.4	0.4	1.2	-0.6	-1.0	0.4	0.2	0.3	0.0	1.1	0.5
Glaucoma (self-reported)	0.4	0.5	1.1	0.6	-0.9	0.8	0.3	0.8	-1.0	0.8	0.5	-0.4	0.3
Gout (self-reported)	0.4	0.5	1.8	1.3	-0.1	0.5	-0.8	0.6	1.0	0.1	-0.1	0.8	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	3.2	-0.5	0.8	-0.1	-0.6	0.1	-0.5	0.4	1.8	0.5	0.4
Comparative height size at age 10	0.4	2.0	6.5	1.7	0.1	1.5	1.2	-0.5	2.5	-1.3	-1.5	-1.2	-1.1
Age at last live birth	0.4	0.5	1.2	-0.9	0.1	0.7	1.0	-0.9	-0.2	-0.7	0.4	-0.0	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.3	0.3	1.1	-0.5	0.5	0.5	0.2	0.8	-0.5	1.1	0.4
Supplements: Vitamin C	0.4	0.5	1.6	0.8	0.6	-0.4	0.4	1.3	1.1	0.0	0.5	0.3	0.9
Eye problems/disorders: Cataract	0.4	0.4	1.2	0.1	0.5	-0.1	0.8	-1.0	0.8	-1.1	-0.1	-0.4	-0.7
Breast cancer (self-reported)	0.4	0.4	1.5	0.7	0.2	-0.7	1.2	0.5	0.1	0.8	-0.7	0.8	0.1
Illnesses of father: None of the above (group 1)	0.4	0.5	1.4	0.9	0.2	-0.4	-0.5	-0.2	1.2	-0.4	-0.9	-0.1	-0.8
Hearing aid user	0.4	0.4	1.3	0.4	0.8	0.6	1.2	-0.5	-0.4	0.6	-0.8	0.4	0.1
Financial situation satisfaction	0.4	0.6	2.1	-0.9	-0.6	0.2	-0.2	-1.1	-0.5	-0.3	-0.6	-1.4	-0.7
Ever depressed for a whole week	0.4	0.5	1.2	-0.8	-0.9	0.3	0.7	-0.8	-0.6	-0.1	-0.3	-1.1	-0.3
Pack years of smoking	0.4	0.6	1.6	-0.5	-1.0	-1.2	-0.2	-0.8	-0.7	-1.0	-0.4	-1.0	-0.6
Schizophrenia vs Biploar Disorder	0.3	0.4	1.7	0.4	0.4	0.9	-1.3	-0.3	0.3	-0.2	0.5	-0.7	-0.6
Ulcerative Colitis (UC)	0.3	0.5	2.0	0.3	-0.4	0.6	1.4	-0.8	0.2	-0.5	-0.1	-1.0	-0.4
Body Mass Index (BMI) (2010)	0.3	0.4	0.9	0.9	-0.7	0.1	-0.9	-0.1	0.9	0.1	-0.5	-0.7	-0.2
HDL Cholesterol	0.3	0.5	2.0	-1.4	-0.8	-0.8	0.2	-1.0	-0.2	0.0	-0.6	-0.4	-0.8
Primary Biliary Cirrhosis	0.3	0.5	1.2	0.8	0.8	1.1	0.6	0.2	0.8	-0.8	0.2	-0.6	-0.2
Hearing difficulty/problems: Yes	0.3	0.5	1.2	0.0	-1.1	0.7	0.8	-0.7	-0.2	-0.5	-0.7	-0.9	-0.7
Systolic blood pressure, automated reading	0.3	0.9	4.9	0.9	1.0	-0.3	-2.2	0.5	0.4	-0.2	1.0	-0.8	0.3
Medication for hormone replacement therapy	0.3	0.4	0.9	0.4	0.3	0.9	0.5	0.5	0.9	-0.2	0.1	1.0	0.3
Medication: Co-codamol	0.3	0.4	2.7	0.1	-0.1	-0.3	1.6	0.2	0.2	0.0	-1.0	0.3	-0.1
Leg fat-free mass (left)	0.3	1.5	4.8	0.6	-2.2	-0.1	1.4	-1.2	1.0	-0.8	-1.8	-0.4	-1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	3.8	-0.5	0.7	-0.7	0.2	0.2	-0.0	0.9	-0.4	1.9	1.0
Leg predicted mass (left)	0.3	1.6	5.2	0.5	-2.3	-0.2	1.3	-1.2	1.0	-0.8	-1.9	-0.5	-1.4
Waist circumference	0.3	1.0	3.6	0.1	-1.5	-0.2	1.8	-0.5	0.3	-0.0	-1.9	-0.1	-0.9
Had menopause	0.3	0.4	0.9	0.9	-0.2	-0.9	0.8	-0.5	0.8	-0.9	-0.3	0.3	-0.2
Had other major operations	0.3	0.3	1.1	0.5	0.0	0.9	1.0	0.5	-0.5	0.3	0.2	0.3	0.5
Financial difficulties in last 2 years	0.3	0.4	1.2	-1.1	-0.0	-0.7	-0.4	0.7	-0.8	1.0	0.0	-0.5	0.6
Neuroticism score	0.3	0.6	2.0	-1.1	0.3	1.4	0.7	-0.1	-1.0	0.6	0.4	-0.0	0.3
Mouth/teeth dental problems: Dentures	0.3	0.5	1.6	0.8	1.0	-0.0	-1.1	-0.1	0.3	-0.7	-0.0	-1.3	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.9	0.7	0.0	0.3	1.4	0.3	0.5	0.4	-0.4	0.7	0.6
Hair/balding pattern: Pattern 4	0.3	0.7	3.3	-0.5	-1.8	-1.1	-0.3	-0.5	-0.3	-0.4	-1.0	-0.4	-0.5
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	2.9	1.7	-0.2	-0.2	-0.4	0.2	0.2	-0.2	-0.8	0.3	-0.1
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.2	0.6	1.5	0.2	0.3	0.5	0.8	-0.3	0.7	-0.4	-0.1
Age at first live birth	0.3	0.5	1.3	0.2	0.5	0.0	0.9	-0.6	1.0	-1.1	-0.4	-0.5	-1.1
Qualifications: College or University degree	0.3	0.9	2.4	0.6	-1.2	-0.1	-1.0	-0.3	1.4	-1.6	-0.6	-0.9	-0.8
Medication: Allopurinol	0.3	0.4	1.0	0.3	0.3	0.5	-1.0	0.9	0.2	0.9	0.1	0.5	1.0
Suffer from ‘nerves’	0.3	0.4	2.6	0.6	0.3	1.6	-0.5	0.4	-0.2	0.0	0.6	-0.1	0.5
Leg fat-free mass (right)	0.3	1.6	4.7	0.3	-2.2	-0.1	0.8	-1.4	0.8	-0.9	-2.0	-0.8	-1.6
Arm fat percentage (left)	0.3	1.1	3.1	-1.0	-1.8	-0.7	0.7	-1.0	-0.8	0.2	-1.7	0.0	-1.1
Friendships satisfaction	0.3	0.4	1.4	-0.7	0.1	-1.2	-0.2	-0.9	-0.3	-0.3	-0.5	-0.7	-0.5
Leg predicted mass (right)	0.3	1.6	4.6	0.4	-2.1	-0.2	0.8	-1.4	0.9	-0.9	-2.0	-0.8	-1.6
Guilty feelings	0.3	0.4	2.9	-0.3	0.9	-0.0	1.7	0.1	-0.5	0.3	-0.1	-0.6	0.2
Eye problems/disorders: Glaucoma	0.3	0.3	0.9	0.3	0.1	-0.3	-0.0	0.9	-0.7	0.6	0.9	0.4	0.5
Pain type(s) experienced in last month: Hip pain	0.3	0.3	2.1	0.4	0.1	0.9	1.5	-0.0	0.2	-0.1	0.1	0.1	-0.0
Leg fat percentage (left)	0.3	1.1	3.3	-1.8	-1.0	-1.0	0.8	-1.1	-1.4	0.3	-0.8	-0.1	-0.9
Alzheimer’s Disease (including proxy)	0.2	0.3	0.9	-0.0	-0.5	0.1	-0.9	-0.0	-0.1	0.1	-0.8	-0.6	-1.0
Mean Putamen Volume	0.2	0.2	0.4	0.6	0.1	0.4	0.5	0.6	0.6	-0.4	0.0	0.2	0.2
Schizophrenia (2014)	0.2	0.5	0.8	-0.1	-0.9	-0.5	0.5	-0.8	0.9	-0.8	-0.9	-0.6	-0.9
Triglycerides	0.2	0.4	1.4	-0.7	-0.2	1.2	-0.3	-0.1	-0.6	0.3	0.9	0.3	0.6
Waist Hip Ratio (WHR)	0.2	0.9	2.9	0.9	1.1	1.6	0.1	0.3	1.7	-0.5	-0.7	-0.6	-0.3
Tanning	0.2	2.5	6.1	1.8	2.2	1.5	-0.1	1.6	2.5	0.5	0.6	1.9	1.3
Trunk fat percentage	0.2	0.9	2.4	-1.5	-1.2	-0.7	0.2	-0.6	-1.3	0.7	-1.0	0.4	-0.6
Sitting height	0.2	1.2	2.2	0.5	-1.0	1.4	0.6	-0.9	1.2	-1.4	-0.9	-1.3	-1.5
Trunk fat mass	0.2	0.7	1.9	-1.1	-1.4	-0.3	0.7	-0.6	-0.9	0.6	-1.2	0.4	-0.6
Forced vital capacity (FVC)	0.2	0.9	4.0	0.5	0.6	0.6	-2.0	-1.1	-0.5	-0.0	-0.7	-1.5	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.1	-0.9	-0.4	-0.6	0.9	-1.1	0.1	-0.1	-0.7	1.0	0.0
Fluid intelligence score	0.2	0.3	1.6	1.3	0.2	0.9	0.3	-0.7	-0.0	0.2	0.4	-0.4	-0.0
Weight	0.2	1.0	3.7	0.1	-1.9	-0.1	1.3	-0.9	0.1	-0.1	-1.7	-0.1	-1.1
Arm fat percentage (right)	0.2	1.0	3.0	-0.7	-1.7	-0.9	0.7	-0.9	-0.6	0.1	-1.6	-0.1	-1.1
Trunk fat-free mass	0.2	1.1	4.1	1.6	-1.0	1.0	2.0	-0.1	1.4	-0.6	-0.6	0.2	-0.3
Hip circumference	0.2	1.1	3.9	-0.5	-1.7	-0.3	2.0	-0.5	-0.6	0.4	-1.5	0.4	-0.7
Worrier / anxious feelings	0.2	0.3	1.1	-1.1	0.2	0.6	0.7	-0.3	-0.3	0.2	-0.4	0.8	-0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	4.4	0.3	0.1	0.6	-2.1	-0.7	-0.6	0.3	-1.1	-1.0	-0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.7	1.0	-0.1	-0.2	0.3	0.0	1.1	-1.3	-0.2	-0.2	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	3.0	-0.3	0.0	0.5	-1.7	-0.7	-0.8	-0.1	-1.1	-1.1	-0.6
Arm fat mass (right)	0.2	0.8	3.1	-0.0	-1.7	-0.5	1.1	-0.6	-0.3	0.3	-1.5	0.1	-0.9
Trunk predicted mass	0.2	1.1	4.0	1.6	-1.0	0.9	2.0	-0.1	1.4	-0.6	-0.6	0.2	-0.3
Standing height	0.2	2.3	8.2	1.7	1.1	2.9	0.8	1.6	1.0	0.7	0.8	1.9	1.5
Blood clot in the leg (DVT)	0.2	0.3	1.1	-0.9	-0.4	0.5	0.1	-0.7	-1.1	0.1	0.3	0.3	0.1
Forced vital capacity (FVC), Best measure	0.2	0.9	2.6	0.1	0.3	0.5	-1.6	-0.9	-0.5	-0.5	-1.0	-1.6	-0.9
Body fat percentage	0.2	0.9	2.4	-1.5	-1.2	-0.7	0.5	-0.7	-1.2	0.5	-1.1	0.3	-0.7
Leg fat percentage (right)	0.2	0.9	2.0	-1.4	-1.1	-0.9	1.2	-0.8	-1.1	0.3	-0.7	0.2	-0.7
Eye problems/disorders: None of the above	0.2	0.2	0.4	0.4	-0.5	-0.0	-0.4	-0.4	0.6	0.1	-0.5	-0.6	-0.3
Whole body fat mass	0.2	0.7	2.3	-0.8	-1.5	-0.4	1.1	-0.6	-0.6	0.3	-1.2	0.4	-0.7
Leg fat mass (right)	0.2	0.8	2.7	-0.5	-1.6	-0.4	1.3	-0.8	-0.3	0.1	-1.4	0.2	-0.9
Family relationship satisfaction	0.2	0.3	2.3	0.1	1.5	-0.1	0.1	-0.2	0.2	-0.2	0.4	-0.3	-0.1
Whole body fat-free mass	0.2	1.0	2.4	1.0	-1.5	0.5	1.6	-0.6	1.2	-0.7	-1.1	-0.1	-0.8
Osteoarthritis (self-reported)	0.2	0.2	1.3	0.3	-0.1	-0.1	-0.3	1.1	0.4	-0.1	0.0	0.7	0.4
Whole body water mass	0.2	1.2	2.6	1.2	-1.6	0.4	1.6	-0.6	1.4	-0.8	-1.3	-0.1	-0.9
Arm fat mass (left)	0.2	0.9	3.2	-0.3	-1.8	-0.3	0.9	-0.8	-0.5	0.3	-1.5	0.1	-1.0
Medication: Blood pressure	0.2	0.4	1.5	-0.2	-0.5	0.2	-0.2	0.6	-1.2	0.3	0.6	0.8	0.4
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.4	0.4	0.4	-0.4	-1.2	-0.0	0.4	-0.5	0.6	-0.1	0.4
Basal metabolic rate	0.2	1.2	3.3	1.0	-1.8	0.3	1.5	-0.7	1.1	-0.6	-1.4	-0.2	-0.9
Arm fat-free mass (left)	0.2	1.0	2.3	1.3	-1.3	0.1	1.5	-0.6	1.2	-0.5	-1.1	-0.0	-0.8
Fractured/broken bones in last 5 years	0.2	0.3	0.9	-0.5	-0.5	-0.1	0.5	0.9	0.0	-0.1	0.4	0.4	0.8
Cholesterol lowering medication	0.2	0.2	1.0	-0.4	-0.4	-0.1	0.2	1.0	-0.6	0.2	0.4	0.7	0.0
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.6	-0.8	-0.4	0.5	0.3	-0.6	-0.7	-0.0	0.3	0.4	0.1
Leg fat mass (left)	0.2	0.8	2.5	-0.6	-1.6	-0.4	1.1	-0.9	-0.4	0.1	-1.4	0.2	-0.9
Arm predicted mass (left)	0.2	0.9	2.3	1.2	-1.5	-0.0	1.5	-0.5	1.0	-0.5	-1.1	-0.0	-0.8
Neuroticism (2016)	0.1	0.2	0.6	-0.5	0.2	0.1	0.3	0.3	-0.5	0.8	0.3	0.7	0.0
Height	0.1	2.1	9.5	0.6	2.2	3.1	0.6	0.5	0.2	0.4	1.6	1.2	0.9
Systolic Blood Pressure	0.1	0.7	2.4	-0.2	0.9	0.8	-1.1	-0.1	-1.0	0.1	1.6	-1.0	0.2
Lung FEV1/FVC ratio	0.1	0.5	1.3	0.6	0.2	0.5	0.7	1.0	1.1	-0.5	-0.2	0.9	0.6
Hair Pigment	0.1	2.3	6.5	-2.5	-1.6	-1.6	0.1	-1.3	-1.6	-1.0	-0.5	-2.2	-1.4
Hand grip strength (right)	0.1	0.3	1.0	0.3	1.0	0.1	-0.5	-0.7	0.7	-0.5	-0.3	-0.4	-0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.4	-0.7	-0.1	-0.5	0.4	-0.0	-0.0	0.3	-0.1	-0.5	-0.5
Pulse rate	0.1	0.2	0.4	0.6	-0.5	-0.2	0.3	0.3	0.5	-0.2	-0.6	-0.3	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.6	-0.4	-0.2	0.6	-0.3	-0.0	-0.8	0.5	-0.4	-0.2	-0.3
Medication: Lansoprazole	0.1	0.1	0.8	-0.1	-0.1	-0.0	-0.1	-0.2	-0.2	-0.4	-0.1	-0.9	-0.6
Arm fat-free mass (right)	0.1	0.7	2.4	0.8	-1.3	0.4	1.6	-0.3	0.9	-0.3	-0.9	0.3	-0.5
Arm predicted mass (right)	0.1	0.7	2.1	1.0	-1.2	0.3	1.5	-0.2	0.9	-0.3	-1.1	0.4	-0.5
Blood Red Count	0.0	0.3	1.0	0.2	0.7	-0.1	-1.0	0.4	0.2	0.3	0.3	-0.3	0.7

Hub : Genes

DCLRE1B

Models

Trait associations