TWAS
hub
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Usage
Models
Genes
Traits
[Hub]/) :
Traits
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Crohns Disease (2017)
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chr14:87,606,646-89,154,624
Best TWAS P=7.56e-10 · Best GWAS P=2.02e-12 conditioned to 0.346
87.6M
87.8M
88M
88.2M
88.4M
88.6M
88.8M
89M
89.2M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Stomach Adenocarcinoma
GALC
0.14
0.05
blup
136
0.05
8.0e-05
1.9
-6.2
7.6e-10
-0.33
0.29
0.20
TRUE
1
NTR
Blood
GALC
0.02
0.00
enet
14
0.01
2.6e-04
6.2
-5.7
1.0e-08
-0.35
0.50
0.21
TRUE
2
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
GPR65
0.09
0.01
blup
56
0.06
1.8e-07
-3.1
5.2
2.5e-07
0.78
0.01
0.96
TRUE