Hub : Genes

GALC

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0860 0.0260 1.1e-06 0.054 0.071 0.074 0.074 0.073 3.6e-07 5.1e-09 2.3e-09 2.4e-09 3.0e-09
2 GTEx Adipose Subcutaneous 0.1890 0.0420 1.7e-10 0.182 NA 0.207 NA 0.206 9.0e-15 NA 8.6e-17 NA 9.8e-17
3 GTEx Adipose Visceral Omentum 0.2550 0.0760 4.0e-04 0.004 NA 0.041 NA 0.027 2.0e-01 NA 3.4e-03 NA 1.5e-02
4 GTEx Artery Aorta 0.1640 0.0630 1.2e-03 0.010 NA 0.028 NA 0.016 8.1e-02 NA 1.1e-02 NA 4.4e-02
5 GTEx Artery Tibial 0.1062 0.0387 3.7e-04 0.010 NA 0.056 NA 0.027 5.1e-02 NA 3.5e-05 NA 3.2e-03
6 GTEx Brain Cerebellar Hemisphere 0.3210 0.0770 5.3e-06 0.239 NA 0.358 NA 0.255 8.3e-07 NA 4.4e-10 NA 3.2e-07
7 GTEx Brain Cerebellum 0.4790 0.0810 2.1e-08 0.313 NA 0.260 NA 0.328 5.9e-10 NA 2.7e-08 NA 2.0e-10
8 GTEx Breast Mammary Tissue 0.1090 0.0400 1.6e-03 0.016 NA 0.012 NA 0.018 4.6e-02 NA 7.9e-02 NA 3.8e-02
9 GTEx Breast Mammary Tissue (Male) 0.1331 0.1320 2.0e-01 -0.010 NA -0.012 NA 0.002 6.3e-01 NA 8.3e-01 NA 2.9e-01
10 GTEx Cells EBV-transformed lymphocytes 0.4340 0.0780 2.8e-08 0.233 NA 0.337 NA 0.357 3.6e-08 NA 9.9e-12 NA 1.7e-12
11 GTEx Cells Transformed fibroblasts 0.2310 0.0470 5.9e-11 0.195 NA 0.168 NA 0.189 1.5e-14 NA 1.4e-12 NA 4.0e-14
12 GTEx Colon Transverse 0.2750 0.0660 8.8e-08 0.060 NA 0.174 NA 0.189 7.8e-04 NA 1.1e-08 NA 2.3e-09
13 GTEx Esophagus Mucosa 0.2320 0.0530 1.4e-08 0.160 NA 0.155 NA 0.158 7.6e-11 NA 1.6e-10 NA 1.0e-10
14 GTEx Heart Left Ventricle 0.1199 0.0454 2.0e-03 0.051 NA 0.043 NA 0.031 1.0e-03 NA 2.4e-03 NA 8.7e-03
15 GTEx Liver 0.6080 0.0740 1.2e-08 0.410 NA 0.452 NA 0.392 1.3e-12 NA 3.8e-14 NA 5.5e-12
16 GTEx Lung 0.2131 0.0450 1.5e-09 0.147 NA 0.183 NA 0.174 2.5e-11 NA 5.5e-14 NA 2.5e-13
17 GTEx Muscle Skeletal 0.1905 0.0375 2.8e-14 0.202 NA 0.198 NA 0.209 1.6e-19 NA 4.2e-19 NA 3.3e-20
18 GTEx Nerve Tibial 0.1373 0.0389 7.7e-06 0.078 NA 0.099 NA 0.131 3.7e-06 NA 1.7e-07 NA 1.6e-09
19 GTEx Pancreas 0.2050 0.0640 5.2e-04 0.121 NA 0.045 NA 0.065 9.1e-06 NA 5.4e-03 NA 1.0e-03
20 GTEx Skin Not Sun Exposed Suprapubic 0.2580 0.0550 3.0e-09 0.279 NA 0.216 NA 0.261 1.2e-15 NA 4.7e-12 NA 1.3e-14
21 GTEx Skin Sun Exposed Lower leg 0.2360 0.0460 2.9e-11 0.203 NA 0.235 NA 0.212 1.1e-16 NA 2.2e-19 NA 1.9e-17
22 GTEx Spleen 0.3350 0.1200 5.6e-03 0.000 NA 0.039 NA 0.057 3.2e-01 NA 3.6e-02 NA 1.4e-02
23 GTEx Stomach 0.2600 0.0730 3.5e-05 0.156 NA 0.143 NA 0.138 6.5e-08 NA 2.4e-07 NA 3.9e-07
24 GTEx Testis 0.3870 0.0620 2.3e-12 0.407 NA 0.438 NA 0.442 2.1e-19 NA 3.0e-21 NA 1.9e-21
25 GTEx Thyroid 0.1450 0.0400 3.0e-06 0.023 NA 0.028 NA 0.037 6.1e-03 NA 2.9e-03 NA 8.0e-04
26 METSIM Adipose 0.0720 0.0247 8.4e-06 0.045 0.036 0.037 0.014 0.043 2.2e-07 3.0e-06 2.7e-06 2.6e-03 4.0e-07
27 NTR Blood 0.0172 0.0074 4.1e-03 0.004 0.005 0.010 0.005 0.006 1.9e-02 5.3e-03 2.6e-04 5.2e-03 4.2e-03
28 YFS Blood 0.1458 0.0250 0.0e+00 0.201 0.189 0.214 0.204 0.216 9.2e-64 1.8e-59 2.9e-68 1.2e-64 7.3e-69
29 TCGA Breast Invasive Carcinoma 0.0678 0.0209 8.1e-13 0.093 0.069 0.091 NA 0.088 1.8e-18 4.6e-14 5.5e-18 NA 1.6e-17
30 TCGA Colon Adenocarcinoma 0.0770 0.0380 1.9e-03 0.049 0.028 0.011 NA 0.031 8.0e-04 8.7e-03 7.2e-02 NA 6.9e-03
31 TCGA Glioblastoma Multiforme 0.1240 0.0650 9.2e-03 0.102 0.059 0.073 NA 0.099 5.3e-04 7.4e-03 3.1e-03 NA 6.4e-04
32 TCGA Head and Neck Squamous Cell Carcinoma 0.0688 0.0259 1.8e-06 0.062 0.057 0.049 NA 0.057 1.6e-07 4.9e-07 3.4e-06 NA 5.5e-07
33 TCGA Kidney Renal Papillary Cell Carcinoma 0.0780 0.0370 1.4e-03 0.030 0.049 0.034 NA 0.040 7.2e-03 8.1e-04 4.5e-03 NA 2.4e-03
34 TCGA Brain Lower Grade Glioma 0.1048 0.0432 5.9e-06 0.058 0.050 0.051 NA 0.051 3.2e-07 2.2e-06 1.8e-06 NA 1.6e-06
35 TCGA Lung Adenocarcinoma 0.0551 0.0236 3.9e-05 0.022 0.037 0.035 NA 0.034 1.0e-03 3.0e-05 5.9e-05 NA 6.6e-05
36 TCGA Lung Squamous Cell Carcinoma 0.0763 0.0306 1.1e-06 0.066 0.052 0.061 NA 0.059 5.9e-08 1.3e-06 1.7e-07 NA 2.8e-07
37 TCGA Ovarian Serous Cystadenocarcinoma 0.1930 0.0660 2.0e-06 0.026 0.063 0.051 NA 0.062 6.7e-03 4.6e-05 2.4e-04 NA 5.5e-05
38 TCGA Prostate Adenocarcinoma 0.0838 0.0302 7.9e-07 0.087 0.064 0.066 NA 0.080 2.4e-09 2.9e-07 1.9e-07 NA 1.1e-08
39 TCGA Rectum Adenocarcinoma 0.2320 0.1040 5.2e-03 0.138 0.136 0.126 NA 0.141 4.0e-04 4.4e-04 7.2e-04 NA 3.5e-04
40 TCGA Stomach Adenocarcinoma 0.1350 0.0510 4.3e-05 0.054 0.055 0.021 NA 0.018 9.0e-05 8.0e-05 1.1e-02 NA 1.8e-02
41 TCGA Testicular Germ Cell Tumors 0.2570 0.0820 1.5e-05 0.172 0.155 0.161 NA 0.193 1.1e-06 3.9e-06 2.5e-06 NA 2.3e-07
42 TCGA Thyroid Carcinoma 0.0790 0.0330 1.1e-04 0.070 0.049 0.059 NA 0.064 2.3e-07 1.3e-05 2.1e-06 NA 7.1e-07

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42
Bipolar Disorder (2018) 0.4 0.7 3.1 -0.9 0.7 0.1 0.1 -1.8 1.6 1.4 -0.5 0.1 0.9 0.6 1.0 0.6 0.8 -0.4 1.0 0.8 1.5 0.3 0.4 0.5 1.6 0.7 0.5 1.3 0.7 -0.7 -1.1 0.4 0.8 0.5 0.5 0.5 0.4 0.8 0.8 0.1 0.2 1.1 -0.7 0.6 0.3
Bipolar Disorder or Schizophrenia 0.4 1.0 3.5 -0.0 1.3 -0.2 0.6 -0.5 1.2 1.4 0.7 -0.2 0.8 1.0 1.1 1.0 1.7 -0.4 1.0 1.3 1.3 0.7 0.7 1.0 1.7 0.6 0.8 1.3 1.5 -0.1 -0.3 0.7 1.3 1.3 0.6 1.5 0.9 1.0 0.9 1.3 0.6 1.9 -0.7 0.8 0.7
Depressed Affect (Nagel 2018) 2.4 5.1 16.1 -2.9 -2.8 -2.2 -3.3 -2.9 0.2 -1.8 -3.8 0.6 -0.3 -2.5 -1.9 -1.4 -2.4 2.0 -0.6 -2.5 -1.2 -2.0 -2.0 -2.3 0.3 -1.2 -1.3 -2.4 -4.0 -2.1 -3.8 -2.0 -2.4 -1.8 -1.6 -3.5 -2.3 -1.4 -2.1 -1.6 -1.9 -3.0 -2.3 -1.5 -2.0
Depression (Nagel 2018) 1.6 2.5 11.2 -0.9 -1.6 -1.7 -1.8 -3.1 -0.3 -1.1 -1.8 0.8 -0.9 -1.7 -2.1 -1.0 -2.3 1.4 -1.0 -1.4 -1.3 -1.3 -1.4 -1.0 0.2 -0.8 -1.1 -1.6 -2.3 -3.3 -1.5 -1.4 -1.2 -1.3 -1.4 -1.9 -1.5 -1.5 -1.7 -0.5 -1.3 -1.1 -2.5 -1.2 -1.3
Intelligence (Savage-Jansen 2018) 0.2 0.5 3.1 -0.6 0.7 1.3 0.5 0.4 0.6 0.5 1.8 0.9 0.5 0.8 0.7 0.5 1.2 -0.7 0.5 0.8 0.5 0.6 0.5 0.3 0.3 0.8 0.5 0.4 -0.1 -0.4 -0.8 0.6 0.5 0.6 0.4 0.3 0.7 0.4 0.4 1.3 0.4 0.3 0.4 0.7 0.6
Neuroticism (Nagel 2018) 0.8 1.9 7.9 -1.5 -1.4 -1.7 -2.1 -2.8 0.2 -1.0 -2.7 0.8 -0.2 -1.6 -1.5 -0.4 -1.4 1.1 -0.3 -1.2 -0.9 -1.1 -1.0 -1.4 -0.0 -0.5 -0.6 -1.3 -2.2 -1.6 -2.4 -1.1 -1.0 -1.1 -1.2 -2.0 -1.6 -0.6 -1.2 -0.3 -0.9 -0.9 -2.2 -0.9 -1.1
Schizophrenia (2018) 0.3 0.7 3.2 0.6 1.1 -0.4 0.6 0.7 0.3 0.7 1.2 -0.4 0.3 0.8 0.7 0.7 1.5 -0.2 0.5 1.0 0.5 0.6 0.6 0.9 1.0 -0.0 0.6 0.6 1.4 0.4 0.5 0.6 1.1 1.2 0.4 1.5 0.8 0.5 0.6 1.8 0.7 1.5 -0.5 0.5 0.6
Schizophrenia vs Biploar Disorder 1.5 2.0 4.2 1.3 -1.4 -0.5 -1.4 1.3 -2.0 -1.8 -0.8 -1.0 -1.9 -1.5 -1.8 -1.7 -1.1 0.6 -1.7 -1.8 -1.7 -1.4 -1.4 -1.9 -1.4 -1.4 -1.7 -1.9 -0.6 0.1 1.0 -1.4 -1.9 -1.2 -1.7 -0.6 -1.6 -1.7 -1.5 -0.8 -1.4 -1.1 -0.7 -1.6 -1.4
Worry (Nagel 2018) 0.1 0.3 3.2 -0.3 0.2 -0.5 -0.4 -1.8 0.5 0.4 -1.1 0.2 0.3 -0.2 -0.3 0.5 -0.5 0.1 0.3 0.3 0.2 0.1 0.1 -0.1 -0.5 0.5 0.4 0.2 0.1 -0.9 -0.7 0.1 0.4 0.1 -0.1 0.0 -0.1 0.2 -0.0 0.8 0.2 1.0 -1.4 0.1 0.1
Alzheimer’s Disease (in mother) 0.8 0.9 3.4 0.4 1.1 0.5 0.8 0.9 0.5 0.9 1.4 0.3 0.5 1.0 1.4 0.5 1.0 -0.4 0.9 1.0 1.1 0.7 0.7 1.6 1.3 1.2 0.5 1.3 1.9 0.7 0.9 0.7 0.8 0.8 0.7 1.2 0.7 0.8 1.0 0.7 0.6 1.3 0.8 0.8 0.7
Alzheimer’s Disease (in father) 0.8 0.9 5.6 1.7 0.3 2.2 0.5 2.0 -1.2 -0.4 2.4 -0.3 -0.7 0.3 0.5 -0.6 0.5 0.6 -0.6 0.1 -0.5 -0.1 -0.1 0.1 -1.4 -0.4 -0.5 0.5 0.8 1.8 1.8 -0.1 -0.1 0.5 -0.1 1.9 0.1 -0.4 0.4 0.3 -0.2 -0.4 0.9 -0.4 -0.1
Alzheimer’s Disease (including proxy) 1.0 1.4 5.7 0.1 1.2 2.4 0.6 1.8 0.6 0.8 2.2 -0.5 0.8 1.1 2.1 0.5 1.6 -0.3 1.2 0.9 1.4 0.7 0.7 1.4 0.8 0.9 0.6 1.6 1.6 2.0 0.5 0.7 0.6 1.0 0.8 1.7 0.8 0.9 1.1 0.9 0.6 0.6 1.6 0.9 0.7
Crohns Disease (2017) 3.8 8.4 37.8 -0.4 -2.7 -4.0 -1.9 -3.4 -1.9 -3.1 -4.6 -0.7 -2.0 -2.4 -5.1 -1.8 -4.4 0.6 -2.6 -2.0 -3.5 -1.9 -1.7 -2.2 -0.1 -0.0 -2.1 -4.6 -3.9 -5.7 -1.8 -1.8 -1.5 -2.6 -1.9 -4.7 -1.8 -2.8 -2.5 0.0 -2.1 -1.8 -6.2 -2.3 -1.9
Irritable Bowel Disease (IBD) 1.6 3.8 20.9 -1.0 -1.2 -3.7 -0.8 -2.3 -0.7 -1.6 -4.3 -1.4 -0.6 -0.7 -3.9 -0.2 -3.0 -1.1 -1.0 -0.6 -2.0 -0.2 0.0 -0.6 1.6 0.7 -0.5 -3.4 -2.7 -4.6 -1.8 -0.1 -0.0 -0.8 -0.6 -3.5 -0.2 -0.9 -0.9 1.1 -0.4 -0.5 -4.6 -0.6 -0.2
Ulcerative Colitis (UC) 1.1 2.0 7.9 -1.3 0.9 -2.0 0.6 -0.8 1.0 0.7 -2.3 -1.5 1.2 1.3 -1.0 1.6 -0.3 -2.3 1.2 1.2 0.4 1.6 1.8 1.2 2.8 1.2 1.4 -0.6 -0.6 -1.9 -1.3 1.7 1.6 1.4 1.0 -1.0 1.5 1.3 1.0 1.9 1.4 1.1 -1.3 1.4 1.6
Major Depression (MDD) 0.8 1.0 2.9 0.4 -1.0 -1.7 -0.7 -0.5 -1.0 -1.1 -0.8 1.2 -1.2 -1.4 -1.5 -0.8 -1.4 -0.1 -1.3 -0.9 -1.4 -0.9 -1.0 -0.6 -1.6 -0.5 -0.8 -1.2 -0.4 -0.7 0.4 -1.0 -0.8 -1.1 -1.0 -1.1 -0.9 -1.1 -1.1 -1.0 -0.7 -0.4 -0.9 -1.1 -0.9
Reaction Time 0.3 0.5 1.7 -1.3 0.5 -1.2 0.3 -1.1 1.3 0.8 -0.3 0.2 1.0 0.5 0.1 1.0 0.1 -0.2 0.7 0.4 0.4 0.6 0.7 0.5 0.7 0.5 1.1 0.4 -0.8 -0.4 -1.2 0.6 0.4 0.5 1.1 -0.3 0.5 0.7 0.6 0.9 0.8 -0.1 -0.4 0.7 0.6
Verbal and Numeric Reasoning (VNR) 0.1 0.3 3.4 0.7 -0.0 1.0 0.1 0.1 -0.3 -0.3 1.8 0.5 -0.5 -0.2 -0.1 -0.3 0.3 0.3 -0.3 -0.4 -0.0 -0.4 -0.4 -0.6 -1.2 0.0 -0.4 -0.0 0.4 -0.6 0.4 -0.4 -0.7 -0.3 -0.8 0.4 -0.4 -0.6 -0.7 0.3 -0.4 0.3 -0.0 -0.4 -0.4
Breast Cancer 1.7 4.0 9.1 0.0 -2.5 -0.8 -2.1 -0.3 -2.0 -2.4 -1.4 0.4 -1.8 -2.2 -2.6 -1.9 -2.1 2.1 -2.2 -2.5 -2.5 -2.0 -1.9 -2.4 -2.1 -1.4 -1.8 -2.6 -3.0 -1.0 -0.0 -2.0 -2.3 -1.9 -1.9 -2.1 -2.0 -2.2 -2.2 -1.2 -1.8 -3.0 -1.2 -2.2 -2.0
Ovarian Cancer 3.9 5.2 9.8 1.1 2.6 3.0 2.4 2.6 0.7 2.0 3.1 -1.7 1.6 2.7 1.9 2.1 2.4 -1.9 1.7 2.7 1.3 2.5 2.5 2.1 0.4 2.2 2.1 2.1 2.1 2.3 1.8 2.5 2.5 2.8 2.1 3.1 2.6 2.3 2.5 2.6 2.5 2.0 2.4 2.2 2.5
Prostate Cancer 0.2 0.2 1.0 0.6 -0.3 -0.9 -0.3 0.0 -0.5 -0.1 -0.5 -0.6 -0.4 -0.2 -0.8 -0.3 -0.3 -0.3 -0.3 -0.2 -0.5 -0.2 -0.2 0.1 0.7 -0.1 -0.4 -0.3 -0.1 -0.9 0.7 -0.2 -0.2 -0.5 -0.6 -1.0 -0.8 -0.7 -0.2 -1.0 -0.2 0.1 -0.4 -0.4 -0.2
Age at First Birth 0.3 0.4 5.2 0.4 -0.4 -1.0 -0.1 -0.3 -0.3 -0.3 -0.7 -2.3 -0.3 -0.7 -0.6 -0.1 -0.6 0.3 -0.5 -0.1 -0.4 -0.3 -0.4 -1.0 -0.8 -0.9 -0.1 -0.8 -0.1 -1.5 0.0 -0.4 0.1 -0.4 -0.7 0.0 -0.3 -0.6 -0.6 0.4 -0.1 -0.1 -0.9 -0.3 -0.3
Bipolar Disorder (2011) 0.4 0.4 2.5 0.2 0.7 0.6 0.6 -0.3 0.5 0.6 0.7 -1.6 0.3 0.5 0.5 0.4 -0.1 -0.4 0.5 0.6 0.5 0.4 0.2 0.6 1.6 0.5 0.3 0.5 1.0 -0.4 -0.0 0.3 0.5 0.5 0.1 0.7 0.4 0.5 0.4 0.8 0.3 0.9 -0.0 0.4 0.4
Body Mass Index (BMI) (2010) 0.6 0.9 7.7 -0.7 0.3 -1.9 0.4 -2.0 0.3 0.2 -0.6 0.6 0.3 0.5 -1.1 0.8 -0.4 -1.9 0.3 0.6 -0.4 0.8 0.9 0.4 -0.4 0.5 0.8 -0.9 -0.7 -2.8 -0.4 0.9 0.8 -0.0 0.1 -2.1 0.2 0.1 -0.3 0.7 0.8 0.2 -0.3 0.6 0.8
Coronary Artery Disease (CAD) 0.3 0.3 1.1 0.3 -0.4 -0.9 -0.8 -0.4 -0.3 -0.0 0.5 0.2 -0.7 -0.2 0.1 -0.9 -0.3 0.3 -0.2 -0.6 0.0 -0.9 -0.6 -0.9 -0.0 -0.9 -1.0 0.5 -0.1 0.2 0.2 -0.5 -0.7 -0.4 -1.1 0.0 -0.9 -0.3 -0.8 -0.5 -0.8 -0.4 0.3 -0.8 -0.9
Crohns Disease (2012) 3.7 5.9 23.1 -0.5 -2.3 -2.9 -1.8 -3.2 -1.4 -2.6 -3.0 0.7 -1.6 -2.3 -3.8 -1.6 -3.4 1.3 -2.4 -1.9 -2.9 -1.9 -1.9 -2.2 -0.4 0.2 -1.8 -3.5 -3.1 -4.8 -1.6 -1.8 -1.6 -2.7 -1.5 -4.1 -1.6 -2.6 -2.5 -0.6 -1.8 -1.7 -4.8 -2.1 -1.9
Mean Putamen Volume 0.8 0.9 4.3 -0.0 0.8 -0.1 0.4 1.2 0.8 0.9 2.1 -1.1 0.8 0.7 2.1 0.5 1.9 0.8 0.7 0.8 1.5 0.4 0.3 0.7 0.0 -0.5 0.5 1.4 1.3 1.4 0.3 0.3 0.6 0.3 0.6 1.3 1.1 0.5 0.5 -0.0 0.4 0.7 1.1 0.7 0.4
Fasting Glucose 1.1 1.3 2.8 -0.3 -1.1 -1.0 -1.2 -0.5 -0.5 -0.9 -0.3 0.2 -1.1 -1.2 -1.1 -1.4 -1.4 0.5 -1.1 -1.3 -0.9 -1.3 -1.5 -1.1 1.2 -0.3 -1.4 -1.0 -0.9 -1.6 -0.9 -1.3 -1.4 -1.7 -1.2 -1.4 -1.4 -1.4 -1.2 -1.1 -1.6 -0.8 -1.6 -1.2 -1.3
HbA1C 0.3 0.3 2.4 -1.0 0.0 -0.4 0.2 -0.7 0.8 -0.0 -0.4 -0.4 0.7 0.0 0.4 0.7 0.0 0.2 0.3 -0.1 0.7 -0.0 0.2 -0.1 0.4 1.1 0.7 0.3 -0.6 0.1 -1.6 0.2 -0.1 0.4 0.9 0.7 0.6 0.3 0.5 0.5 0.4 0.2 -0.4 0.2 -0.0
HDL Cholesterol 0.5 0.8 2.3 1.3 -0.4 0.2 -0.7 1.3 -1.1 -0.7 0.2 -1.5 -1.4 -0.8 -0.4 -1.3 -0.1 1.4 -1.1 -0.5 -0.7 -0.9 -1.1 -1.0 -1.0 -0.8 -1.4 -0.4 0.9 0.4 0.9 -0.9 -0.6 -0.5 -0.7 1.0 -0.7 -0.5 -0.5 0.1 -1.2 0.2 -1.0 -1.0 -0.9
LDL Cholesterol 0.5 0.8 1.9 0.2 -1.0 -0.8 -0.5 -0.8 -1.0 -1.3 -0.5 0.6 -1.1 -0.9 -0.8 -1.1 -0.9 0.9 -1.0 -1.0 -0.9 -1.0 -0.9 -1.1 -0.5 -1.3 -1.0 -1.4 -0.9 -0.3 -0.0 -0.9 -0.9 -0.8 -1.0 -0.4 -0.9 -0.7 -0.8 -0.7 -0.9 -1.2 -0.2 -1.0 -1.0
Lupus 2.3 3.5 10.3 -0.4 -2.1 -1.2 -2.1 -0.6 -1.6 -2.1 -3.2 0.9 -1.8 -1.9 -3.0 -1.8 -1.7 0.4 -2.0 -2.1 -2.4 -1.7 -1.7 -2.5 -0.6 -1.3 -1.8 -2.9 -2.6 -1.1 -1.1 -1.7 -1.8 -1.7 -2.1 -2.4 -1.7 -1.6 -1.8 -0.9 -1.8 -1.9 -2.4 -1.9 -1.7
Neuroticism (2016) 1.3 1.9 8.2 -1.5 -1.4 -1.0 -2.1 -1.3 0.2 -1.0 -2.9 -0.4 -0.2 -1.3 -1.0 -0.8 -1.1 1.4 -0.4 -1.7 -0.6 -1.4 -1.2 -0.9 0.5 -1.7 -0.9 -0.9 -2.0 -1.5 -2.1 -1.4 -1.6 -1.0 -0.9 -2.4 -1.3 -0.9 -0.9 -1.8 -1.3 -1.4 -1.8 -1.1 -1.4
Primary Biliary Cirrhosis 1.5 2.1 18.9 4.3 0.9 0.8 1.3 2.5 -2.9 -0.8 1.9 -1.5 -1.6 0.8 -1.2 -0.2 0.4 -1.1 -1.4 1.1 -1.9 0.7 0.7 0.4 -1.9 -0.1 -0.3 -0.8 1.3 0.0 4.3 0.7 1.1 0.3 -0.2 1.1 0.6 -1.0 0.3 0.7 0.7 0.7 -0.2 -0.4 0.7
Rheumatoid Arthritis 0.2 0.3 2.1 -0.0 0.5 -0.5 -0.1 -1.0 0.3 0.4 0.6 0.2 -0.1 0.4 -0.4 0.2 -0.5 -0.9 -0.1 0.5 0.1 0.4 0.3 0.7 0.7 1.4 0.2 -0.2 0.1 -1.1 -0.1 0.4 0.5 -0.2 0.9 -0.5 0.4 -0.4 0.2 0.7 0.2 0.7 -1.4 0.3 0.4
Schizophrenia (2014) 0.5 1.1 3.5 0.2 1.4 -0.6 0.5 0.5 0.9 1.2 0.8 -1.1 0.7 1.2 1.1 1.0 1.6 -0.5 0.9 1.2 1.2 0.8 0.9 1.0 1.8 0.7 0.9 1.0 1.9 -0.2 0.0 0.9 1.2 1.1 1.0 1.3 0.9 0.8 1.1 1.5 0.8 1.8 -0.6 0.9 0.8
Triglycerides 0.1 0.2 1.6 -0.8 0.2 -0.5 0.7 0.0 0.5 -0.1 -0.2 -1.3 0.6 0.3 -0.3 0.8 -0.3 -1.1 0.4 0.1 0.0 0.2 0.5 -0.1 0.2 -0.2 0.8 -0.4 -0.2 -0.7 -0.6 0.3 0.2 0.5 0.2 -0.1 0.3 0.4 0.0 0.3 0.6 -0.0 0.3 0.3 0.2
Type 2 Diabetes (T2D) (2012) 0.2 0.3 2.6 -0.6 0.1 -0.2 0.4 -1.4 0.7 0.5 -0.7 1.6 0.2 0.2 0.1 0.2 0.0 -0.2 0.3 0.1 0.4 0.2 0.1 0.4 1.3 0.6 0.2 0.2 0.0 -1.1 -0.6 0.0 -0.1 -0.1 0.1 -0.3 -0.0 0.2 -0.1 -0.4 0.0 0.2 -0.0 0.2 0.2
Ulcerative Colitis 1.1 1.6 9.0 -1.8 0.6 -1.3 -0.2 -1.6 1.7 0.8 -2.3 -0.9 1.1 0.5 -0.4 1.2 0.4 -1.4 1.0 0.8 0.8 1.0 0.9 0.6 3.0 1.2 1.0 -0.0 0.1 -2.1 -2.0 1.0 1.1 0.8 1.1 -0.9 1.1 1.3 0.8 1.5 0.7 1.8 -2.0 1.1 1.0
Blood Eosinophil Count 0.6 4.5 18.6 -2.1 -2.2 -4.3 -2.6 -3.3 -0.1 -1.7 -3.6 -0.1 -0.4 -2.2 -2.8 -0.7 -2.9 -0.0 -0.5 -1.6 -1.7 -1.4 -1.4 -1.2 0.2 -0.3 -0.9 -2.9 -3.4 -3.6 -3.1 -1.4 -1.0 -1.2 -2.4 -3.6 -2.0 -1.4 -2.3 -0.4 -1.3 -1.7 -3.2 -1.2 -1.4
Blood Platelet Count 0.1 1.6 6.5 -1.5 0.9 1.5 0.5 -0.9 2.5 1.9 -0.4 1.5 1.8 -0.6 1.9 1.6 1.2 -0.2 1.4 1.0 1.5 0.8 -0.2 1.0 1.4 0.8 1.6 2.2 1.5 0.6 -1.1 0.1 1.1 0.7 1.6 0.8 1.0 1.4 1.0 -0.4 1.0 1.8 0.8 1.4 0.8
Blood Red Count 0.3 2.8 6.1 -0.3 -1.8 -1.1 -1.3 -1.1 -1.2 -2.0 -0.7 -0.7 -1.3 -1.7 -1.2 -1.7 -2.5 2.2 -1.4 -2.1 -1.4 -1.9 -1.8 -1.5 -0.2 -1.7 -1.6 -1.7 -1.6 -1.5 -0.7 -1.9 -2.1 -2.1 -1.6 -2.4 -1.9 -1.6 -2.2 -2.4 -1.8 -2.2 -0.4 -1.7 -1.9
Blood White Count 0.1 0.9 7.9 -1.5 0.5 0.3 0.5 -0.9 1.2 1.2 0.4 2.8 1.3 0.8 1.3 0.7 0.1 -0.3 1.0 0.7 1.1 0.7 0.7 0.9 1.7 0.7 0.8 1.1 -0.4 -0.4 -0.9 0.7 0.7 0.3 1.4 -0.7 0.7 0.4 0.7 -0.7 0.7 -0.2 0.8 1.0 0.7
Heel T-Score 0.1 0.6 2.4 -0.6 -1.1 -0.1 -0.5 0.5 -0.4 -0.8 -1.6 -0.7 -0.2 -0.8 -0.8 -0.5 -1.0 1.3 -0.4 -0.8 -0.8 -0.6 -0.5 -0.9 -1.4 -0.5 -0.3 -1.0 -1.5 0.6 -0.5 -0.6 -0.7 -0.4 -0.3 -0.8 -0.8 -0.3 -0.4 -0.9 -0.4 -1.3 -0.2 -0.6 -0.6
BMI 3.1 17.9 59.6 -0.6 -4.6 -5.6 -2.8 -2.4 -3.7 -4.9 -4.2 0.4 -3.3 -4.0 -5.6 -3.7 -6.5 1.4 -3.6 -4.3 -5.0 -3.5 -3.5 -3.5 -2.7 -1.4 -3.6 -6.5 -6.1 -5.2 -1.5 -3.5 -4.1 -4.3 -4.6 -7.7 -4.5 -5.0 -4.8 -3.5 -3.4 -5.8 -3.3 -3.8 -3.5
Height 0.1 1.3 4.6 -0.8 0.6 1.7 0.2 1.3 1.2 0.8 0.7 -2.1 1.6 0.8 1.6 1.0 1.2 0.7 1.3 0.5 1.4 0.8 0.8 0.3 0.7 0.9 1.1 1.2 0.5 1.5 -0.6 0.8 0.4 1.1 1.4 2.0 1.3 1.4 1.3 1.1 0.9 -0.1 1.8 1.1 0.8
Waist Hip Ratio (WHR) 0.6 2.7 4.4 0.8 -1.5 -2.0 -1.2 -0.4 -1.9 -2.0 0.0 2.0 -2.0 -1.5 -1.6 -1.9 -2.0 0.8 -2.0 -1.4 -2.0 -1.7 -1.7 -1.5 -1.3 -1.9 -1.8 -2.0 -1.2 -1.2 0.4 -1.7 -1.4 -1.9 -2.1 -1.5 -1.4 -1.9 -1.9 -2.1 -1.6 -1.8 -0.9 -1.9 -1.7
Systolic Blood Pressure 0.1 0.4 3.8 -0.1 -0.3 -0.7 0.1 -1.8 -0.2 -0.1 -1.3 0.8 -0.4 -0.3 -1.4 0.0 -1.0 -0.6 -0.4 -0.2 -0.7 0.0 -0.0 -0.3 0.7 0.3 -0.1 -0.7 -0.4 -2.0 -0.0 0.0 0.0 -0.3 -0.2 -0.9 0.0 -0.2 -0.2 -0.5 -0.1 0.4 -1.1 -0.2 0.0
Smoking Status 0.5 1.1 3.0 0.4 1.2 1.7 1.5 0.5 0.3 0.8 0.8 1.3 0.9 1.2 0.1 1.2 0.3 -1.4 0.7 1.1 0.1 1.4 1.4 1.1 0.8 1.2 1.2 0.6 0.9 1.7 0.6 1.4 1.2 0.9 0.9 0.6 1.2 1.0 1.1 0.6 1.4 1.2 1.0 1.1 1.4
Allergy or Eczema 0.7 1.7 4.6 -0.7 1.4 -1.5 1.0 0.2 1.0 1.3 0.4 -1.2 1.4 1.4 0.3 1.6 0.3 -1.9 1.2 1.4 0.6 1.8 1.7 2.0 1.2 2.0 1.5 0.6 -0.2 0.8 -0.7 1.8 1.4 1.5 1.6 0.2 1.6 1.2 1.4 2.1 1.6 0.7 -0.1 1.6 1.8
Cardiovascular Disease 0.2 0.6 3.8 0.2 0.3 -0.9 0.6 -0.8 -0.4 0.1 -0.8 1.5 0.3 0.5 -1.1 0.7 -0.3 -1.1 0.1 0.5 -0.7 0.9 0.9 0.5 0.3 1.3 0.6 -0.6 -0.8 -2.0 0.5 0.9 0.5 0.1 0.4 -1.4 0.7 -0.2 0.4 0.6 0.9 -0.1 -0.9 0.5 0.9
Hypothyroidism (self reported) 0.6 1.4 6.3 2.2 -0.5 1.9 0.1 2.5 -2.2 -1.3 1.7 -0.8 -1.5 -0.4 -0.9 -1.2 -0.1 0.5 -1.4 -0.8 -1.6 -0.7 -0.7 -0.5 -0.8 -1.1 -1.2 -0.8 -0.2 1.1 2.1 -0.7 -1.1 -0.9 -1.2 -0.1 -0.7 -1.4 -1.0 -1.0 -0.7 -1.2 0.8 -1.1 -0.7
Respiratory disease 0.1 0.1 1.5 -0.1 -0.4 1.1 0.2 0.1 -0.0 -0.0 -1.2 -0.3 0.3 -0.3 -0.0 0.0 -0.1 -0.5 0.4 -0.1 -0.0 -0.1 -0.0 -0.6 -0.3 0.2 -0.0 0.2 -0.5 0.2 0.2 -0.1 0.1 0.1 -0.3 -0.6 -0.5 -0.1 -0.1 -0.8 -0.0 -0.2 0.0 -0.1 -0.1
Type 2 Diabetes (T2D) (2018) 0.8 1.4 5.3 -1.7 -1.3 -1.9 -1.5 -0.2 0.2 -0.9 -1.4 -2.0 0.1 -0.8 -0.7 -0.7 -1.4 0.6 -0.1 -1.5 -0.3 -0.9 -0.9 -0.5 1.6 -0.1 -0.6 -1.3 -2.3 -1.0 -2.0 -0.9 -1.6 -0.8 -0.8 -2.3 -0.6 -0.8 -1.1 -0.9 -0.9 -2.3 -0.5 -0.6 -0.9
Lung FEV1/FVC ratio 0.7 3.3 6.8 -0.5 -2.2 0.1 -2.1 -0.7 -1.0 -1.7 -0.8 0.0 -1.7 -2.2 -0.9 -2.4 -1.7 2.3 -1.7 -2.3 -1.4 -2.3 -2.3 -1.8 -1.6 -1.8 -2.2 -1.1 -2.0 -0.5 -0.9 -2.3 -2.5 -2.2 -1.8 -1.4 -2.3 -1.6 -2.0 -2.6 -2.4 -2.5 -0.4 -2.0 -2.3
Lung FVC 0.6 2.9 15.0 3.0 2.4 1.8 2.4 2.5 -0.9 1.0 3.9 -0.3 -0.2 2.0 1.0 0.8 2.0 -1.3 0.1 2.1 0.2 1.6 1.5 2.0 -0.6 0.4 0.8 1.3 3.3 0.8 3.1 1.6 1.7 1.1 0.8 1.7 1.3 0.4 1.2 0.8 1.5 2.3 1.6 0.9 1.6
Neuroticism 0.2 0.5 3.1 -1.2 -0.5 -0.8 -1.0 -1.8 0.6 -0.1 -1.5 0.4 0.5 -0.6 -0.9 0.3 -0.4 0.2 0.5 -0.7 -0.2 -0.2 -0.1 -0.6 -0.4 -0.2 0.2 -0.3 -1.3 -0.8 -1.6 -0.2 -0.6 -0.2 -0.7 -1.5 -0.8 -0.0 -0.8 0.3 -0.0 -0.1 -1.0 -0.1 -0.2
Chronotype (morning person) 1.3 3.0 8.2 -2.2 1.3 0.9 1.0 -0.2 2.6 2.1 -0.7 -2.0 2.5 1.6 1.5 2.1 1.6 -2.0 2.3 1.4 2.1 1.8 1.8 1.3 2.9 1.7 2.3 1.6 -0.2 0.1 -1.6 1.8 1.6 1.7 2.3 0.4 1.8 1.9 1.8 1.0 1.9 0.5 1.3 2.1 1.8
Hair Pigment 0.0 0.2 1.4 0.1 0.2 -0.8 0.4 -0.4 0.3 0.4 -0.1 0.6 0.2 0.1 0.5 0.2 1.2 0.8 0.3 0.4 0.3 0.2 0.2 0.7 -0.2 -0.0 0.2 0.6 0.4 0.9 0.0 0.2 0.4 0.4 0.2 0.4 0.1 0.6 0.5 0.3 0.2 0.4 0.3 0.2 0.2
Tanning 0.1 1.4 3.4 -0.3 1.3 1.7 1.0 -0.2 1.2 1.6 1.2 0.6 1.4 1.4 1.5 1.2 1.7 -0.7 1.2 1.3 1.4 1.3 1.2 1.0 1.7 1.4 1.2 1.8 0.7 0.1 -0.2 1.2 1.2 1.0 1.4 0.7 1.5 0.9 1.0 0.8 1.2 1.1 0.9 1.3 1.2
Hand grip strength (left) 0.1 0.3 2.1 -0.0 0.1 1.3 -0.6 0.1 0.1 0.1 -0.4 -1.2 0.3 0.1 0.4 0.3 -0.1 0.2 0.6 0.2 0.4 0.3 0.2 0.0 -0.1 0.7 0.2 0.2 0.1 0.1 -0.1 0.3 0.3 1.1 0.2 1.1 0.2 0.6 0.5 1.4 0.2 0.2 -0.4 0.3 0.2
Number of treatments/medications taken 0.3 0.6 3.9 -1.0 0.1 -1.3 0.3 -1.4 0.8 0.8 -1.1 0.9 0.9 0.3 -0.2 0.7 -0.4 -0.9 0.7 0.2 0.3 0.5 0.5 1.1 0.9 1.3 0.7 0.0 -0.7 -1.3 -0.8 0.5 0.2 -0.4 0.1 -2.0 -0.0 0.0 -0.0 -0.7 0.6 -0.1 0.1 0.5 0.5
Average weekly spirits intake 0.6 0.8 2.8 0.9 -0.6 -0.3 -0.2 0.1 -1.4 -0.8 0.2 1.7 -1.1 -0.4 -1.0 -1.0 -0.8 -0.1 -1.0 -0.9 -1.3 -0.5 -0.5 -0.4 -1.3 0.2 -0.9 -0.8 -0.4 -0.4 1.0 -0.5 -1.1 -0.8 -0.8 -1.3 -1.0 -1.3 -0.8 -1.7 -0.5 -1.2 0.7 -0.8 -0.5
Sensitivity / hurt feelings 0.2 0.4 2.8 0.9 0.8 -0.1 1.0 0.4 -0.3 -0.0 0.5 -1.7 0.2 0.5 -0.4 0.6 0.6 -1.4 0.5 0.3 -0.2 0.5 0.6 0.1 -0.4 0.1 0.4 0.1 0.7 -0.9 0.8 0.5 0.3 0.0 -0.6 -1.0 -0.6 -0.0 -0.2 0.5 0.6 1.0 -0.1 0.3 0.5
Frequency of depressed mood in last 2 weeks 0.9 1.3 5.7 -0.2 -0.9 -2.0 -0.8 -1.2 -0.7 -1.1 -0.9 0.1 -1.0 -1.1 -2.1 -0.6 -1.9 1.0 -1.2 -0.9 -1.3 -0.8 -0.7 -0.4 -0.2 -0.2 -0.7 -1.8 -1.4 -2.0 -0.7 -0.7 -0.7 -1.0 -0.7 -1.4 -0.9 -1.3 -1.2 0.3 -0.7 -0.6 -2.4 -0.9 -0.8
Hearing difficulty/problems: Yes 1.3 2.0 4.9 0.1 -1.7 0.9 -1.9 0.4 -1.1 -1.6 -0.7 0.4 -1.3 -1.7 -1.7 -1.4 -0.6 0.9 -1.4 -1.7 -1.8 -1.7 -1.6 -2.2 -1.5 -1.8 -1.4 -1.1 -1.2 0.1 -0.4 -1.7 -1.6 -1.3 -1.9 -0.8 -2.0 -1.2 -1.8 -1.2 -1.4 -1.3 -0.8 -1.8 -1.7
Relative age of first facial hair 1.8 3.6 12.0 1.7 2.5 1.8 2.7 2.6 0.2 1.6 3.5 0.7 0.6 2.2 2.1 1.5 2.0 -1.6 0.8 2.1 1.2 1.7 1.8 2.2 -0.0 1.6 1.5 2.3 3.0 2.4 2.0 1.7 1.8 1.5 2.0 2.7 1.9 1.3 2.2 1.3 1.8 2.3 1.4 1.4 1.7
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 2.8 -1.0 0.9 -1.5 1.1 -1.6 1.4 1.1 -0.0 0.9 0.8 0.8 -0.1 1.1 -0.7 -0.9 0.8 0.9 0.6 0.8 0.8 1.1 1.7 1.6 1.0 0.5 0.7 -1.7 -1.0 0.8 1.0 0.3 0.4 -0.5 0.4 1.0 0.0 1.0 0.8 1.5 0.3 0.9 0.8
Ever used hormone-replacement therapy (HRT) 1.1 1.3 3.1 -0.1 1.3 1.6 1.4 -0.0 0.8 1.1 0.2 -0.1 1.1 1.2 0.6 1.4 0.7 -1.8 1.0 1.5 0.8 1.6 1.5 1.2 0.4 1.4 1.4 0.9 0.9 0.2 0.3 1.6 1.6 0.6 1.5 0.2 1.6 1.2 1.2 0.5 1.5 1.6 0.9 1.4 1.6
Ever had hysterectomy (womb removed) 0.5 0.5 3.1 0.5 0.9 -0.1 0.6 0.9 0.1 0.5 0.4 -0.6 -0.1 0.6 -0.3 0.6 0.3 -1.5 0.2 0.8 -0.0 0.6 0.6 0.6 0.1 1.2 0.5 0.5 1.3 1.3 0.4 0.6 0.8 0.6 0.5 1.1 0.1 0.7 0.6 0.9 0.6 1.8 -0.3 0.3 0.6
Systolic blood pressure, automated reading 0.6 1.9 4.6 -0.3 -1.6 -1.9 -1.1 -1.8 -0.9 -1.2 -2.1 0.6 -1.3 -1.6 -1.8 -1.3 -1.7 0.2 -1.3 -1.4 -1.3 -1.2 -1.3 -1.9 -0.8 -1.2 -1.3 -1.7 -1.0 -1.7 -0.3 -1.2 -1.2 -1.6 -1.2 -1.8 -1.2 -1.1 -1.2 -2.1 -1.3 -0.9 -0.8 -1.2 -1.2
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 2.0 0.6 -0.5 -1.0 0.2 -0.4 -0.6 -0.7 -0.3 0.3 -0.6 -0.4 -0.8 -0.6 -0.7 0.6 -0.9 -0.5 -0.7 -0.4 -0.4 -0.3 0.3 0.2 -0.5 -1.1 -0.8 -1.4 0.5 -0.4 -0.5 -0.9 -0.3 -1.0 -0.2 -1.0 -0.9 0.2 -0.4 -0.7 -0.9 -0.5 -0.4
Angina 0.2 0.3 2.1 -1.3 -0.1 -0.7 -0.6 -0.2 1.2 0.7 -0.7 -0.6 0.7 0.0 -0.2 0.3 0.3 0.3 0.3 -0.3 0.3 0.0 0.1 0.3 0.8 0.1 0.4 0.6 -1.3 -0.3 -1.4 0.0 -0.3 -0.3 0.2 -1.2 0.1 0.0 -0.2 -0.4 0.1 -0.3 -0.2 0.2 0.0
Medication for hormone replacement therapy 1.3 1.4 3.1 -1.1 1.1 0.4 0.9 1.0 1.3 1.2 -0.1 -1.4 1.6 1.3 1.0 1.4 0.9 -1.6 1.6 0.9 1.2 1.5 1.5 1.2 0.4 0.9 1.6 0.9 0.0 1.0 -0.6 1.5 0.8 1.0 1.8 -0.5 1.3 1.3 1.4 1.1 1.5 0.3 1.2 1.6 1.5
Vitamin and mineral supplements 0.4 0.5 3.8 0.5 -0.3 -0.3 0.2 1.8 -0.6 -0.5 0.2 -1.8 -0.3 -0.0 0.0 -0.4 -0.1 -0.4 -0.4 -0.4 -0.4 -0.2 -0.2 -0.3 -0.3 -0.0 -0.4 -0.3 -0.4 -0.3 0.4 -0.2 -0.6 -1.2 -0.5 -1.9 -0.3 -1.0 -0.8 -1.7 -0.2 -0.9 0.6 -0.3 -0.2
Supplements: Zinc 0.2 0.2 1.3 0.1 0.3 0.3 0.8 -0.5 0.0 0.6 0.4 1.2 0.2 0.5 -0.1 0.3 0.1 0.1 0.2 0.1 0.2 0.4 0.4 0.9 0.0 1.0 0.2 0.2 -0.2 -0.2 0.4 0.4 0.0 0.2 0.2 0.0 0.2 -0.0 0.4 0.1 0.4 -0.0 0.3 0.3 0.4
Medication: Co-codamol 0.6 0.7 4.1 -0.5 0.7 -1.8 0.6 -1.3 0.6 0.7 0.1 2.0 0.7 0.8 -0.1 0.9 -0.1 -0.6 0.4 0.9 0.1 0.8 0.8 1.1 1.4 0.5 0.9 0.1 -0.4 -0.6 -0.6 0.8 0.9 0.1 0.8 -1.1 0.9 0.2 0.5 0.3 0.9 0.3 -0.4 0.7 0.8
Medication: Metformin 2.9 4.0 6.6 -1.3 -2.5 -2.1 -2.6 -1.1 -0.6 -2.0 -2.2 -0.1 -1.3 -2.5 -1.6 -2.1 -2.0 2.1 -1.8 -2.5 -1.4 -2.5 -2.5 -2.3 -0.0 -1.3 -2.0 -1.9 -2.3 -1.2 -2.1 -2.5 -2.4 -2.3 -1.8 -1.9 -2.1 -1.7 -2.3 -1.5 -2.4 -2.3 -2.2 -2.1 -2.5
Diabetes (father) 0.7 0.9 4.5 0.3 -0.7 -1.7 0.4 -2.1 -1.0 -0.8 -1.3 1.1 -0.8 -0.6 -1.3 -0.6 -1.3 -0.1 -0.6 -0.5 -1.1 -0.5 -0.5 -0.8 -1.2 -0.7 -0.6 -1.6 -0.7 -2.1 0.3 -0.5 -0.5 -0.4 -1.2 -1.6 -0.9 -0.8 -0.8 -0.4 -0.5 -1.0 -0.6 -0.7 -0.5
Diabetes (mother) 1.0 1.3 3.5 1.1 -1.0 -1.5 -0.9 0.7 -1.8 -1.3 -0.4 0.3 -1.6 -1.0 -1.7 -1.3 -1.2 0.6 -1.3 -0.8 -1.9 -0.9 -1.0 -0.7 -1.4 -0.1 -1.4 -1.6 -0.9 0.4 0.7 -0.9 -0.8 -0.6 -1.8 -0.7 -1.3 -1.2 -1.3 -0.5 -1.0 -1.1 -1.0 -1.3 -0.9
Severe depression (siblings) 0.6 0.7 4.1 0.8 0.9 0.5 0.8 1.5 -0.1 0.3 1.0 0.3 0.6 0.9 0.8 0.8 0.6 -0.8 0.7 0.8 0.3 0.9 0.9 1.0 0.2 0.6 0.8 0.6 0.7 2.0 0.8 0.9 0.8 0.7 0.9 1.0 0.7 0.7 0.9 0.7 0.9 0.2 1.0 0.7 0.9
Pack years adult smoking proportion 0.8 1.3 8.2 -2.8 -0.8 -1.1 -1.6 -1.5 1.6 0.2 -1.0 1.2 1.3 -0.4 0.9 0.0 -0.1 1.5 1.2 -0.9 1.1 -0.4 -0.4 -0.0 1.0 -1.1 0.2 0.3 -2.0 -0.3 -2.9 -0.4 -0.9 -0.2 -0.2 -1.4 -0.4 0.0 -0.4 -1.7 -0.4 -1.6 1.0 0.2 -0.4
Impedance of leg (right) 1.3 6.1 17.0 0.1 2.4 3.8 1.3 2.0 2.0 2.7 2.8 0.8 2.4 2.4 3.3 2.4 3.7 -0.8 2.5 2.2 2.7 2.2 2.2 2.0 0.6 1.3 2.4 3.4 2.6 4.0 0.7 2.1 2.2 2.8 2.2 4.1 2.5 3.0 2.7 1.7 2.3 2.3 2.9 2.3 2.1
Leg fat-free mass (left) 0.6 3.1 8.5 -0.0 -1.7 -2.1 -0.7 -0.4 -1.7 -2.3 -1.6 -2.3 -1.5 -1.6 -2.4 -1.6 -2.7 0.6 -1.8 -1.7 -2.2 -1.4 -1.4 -1.6 -1.1 -0.2 -1.5 -2.9 -2.2 -2.7 -0.4 -1.4 -1.7 -1.8 -1.3 -2.8 -1.4 -2.1 -1.8 -0.6 -1.4 -2.3 -2.0 -1.6 -1.4
Trunk fat percentage 1.4 5.6 23.8 -1.5 -2.7 -3.1 -1.4 -2.1 -1.2 -2.3 -2.4 0.0 -1.2 -2.2 -2.6 -1.9 -3.6 1.2 -1.7 -2.4 -2.2 -1.8 -1.9 -2.0 -1.1 -0.5 -1.7 -3.2 -3.9 -3.5 -1.9 -1.9 -2.4 -2.8 -2.2 -4.9 -2.1 -2.5 -2.8 -2.4 -1.9 -3.7 -1.0 -1.7 -1.8
Hand grip strength (right) 0.2 0.6 2.5 0.3 -0.8 0.8 -1.4 0.2 -0.8 -0.8 -1.0 -1.3 -0.7 -0.7 -0.6 -0.8 -0.9 1.1 -0.5 -0.8 -0.5 -0.7 -0.8 -1.2 -0.1 -0.0 -0.9 -0.8 -0.7 -0.4 -0.1 -0.7 -0.7 0.2 -0.7 0.4 -0.5 -0.6 -0.4 0.7 -0.9 -0.8 -1.6 -0.7 -0.7
Townsend deprivation index at recruitment 0.8 1.1 4.6 -1.1 0.7 -1.9 0.7 -2.1 1.1 0.7 -1.2 1.2 1.0 0.7 -0.4 1.3 -0.5 -1.1 0.8 1.1 0.4 1.0 1.1 1.3 1.3 1.1 1.2 -0.1 -0.2 -2.1 -1.0 1.1 1.4 0.3 0.9 -1.2 0.7 0.8 0.4 1.1 1.1 1.0 -0.6 1.0 1.0
Current tobacco smoking 0.5 0.8 5.9 -1.6 -0.2 -0.6 -0.3 -2.4 1.3 0.2 -1.4 2.2 1.0 -0.2 -0.5 0.6 -1.2 -0.3 0.7 -0.2 0.1 0.1 0.2 0.2 1.2 -0.1 0.6 -0.2 -1.1 -0.7 -2.0 0.1 -0.1 -0.5 0.1 -1.7 -0.4 0.5 -0.0 -0.6 0.2 0.1 -0.3 0.4 0.1
Average weekly fortified wine intake 0.1 0.1 0.8 0.1 0.0 0.5 -0.9 0.1 0.0 -0.0 0.6 0.2 -0.1 0.0 0.0 0.1 -0.0 -0.0 0.0 -0.0 0.2 0.0 0.0 -0.1 0.4 0.3 0.1 -0.2 0.2 -0.1 0.1 0.0 -0.0 0.1 -0.3 0.1 0.2 -0.5 -0.3 0.6 0.0 0.2 -0.2 0.0 0.0
Maternal smoking around birth 0.2 0.3 1.4 0.2 -0.4 0.3 -0.7 0.6 -0.8 -0.9 -0.3 -0.3 -0.8 -0.5 -0.5 -0.6 -0.1 0.3 -0.8 -0.5 -0.7 -0.6 -0.5 -0.8 -1.2 -0.4 -0.6 -0.9 -0.0 -0.3 -0.0 -0.6 -0.5 -0.6 -0.1 0.0 -0.5 -0.5 -0.6 0.1 -0.5 -0.4 -0.6 -0.6 -0.6
Fed-up feelings 2.4 4.3 17.0 -2.6 -2.6 -2.5 -2.8 -1.9 -0.2 -1.9 -4.1 0.3 -0.5 -2.4 -2.5 -1.2 -2.4 1.6 -1.1 -2.5 -1.6 -1.8 -1.8 -2.0 -0.3 -1.1 -1.1 -2.5 -3.8 -1.2 -3.1 -1.8 -2.2 -1.6 -0.7 -3.0 -1.6 -1.2 -1.5 -1.1 -1.6 -2.7 -3.0 -1.5 -1.8
Frequency of unenthusiasm / disinterest in last 2 weeks 2.1 2.8 14.1 -0.3 -1.7 -1.4 -1.3 -2.2 -1.2 -1.7 -1.4 0.8 -1.2 -1.6 -2.4 -1.3 -2.7 1.4 -1.4 -1.6 -1.7 -1.3 -1.3 -1.1 -0.4 -0.4 -1.4 -2.4 -2.4 -3.8 -0.9 -1.2 -1.6 -1.6 -1.4 -2.3 -1.3 -1.9 -1.7 -0.8 -1.3 -1.7 -2.3 -1.3 -1.2
Relative age voice broke 1.3 2.0 8.7 0.5 1.7 1.1 1.6 1.7 0.5 1.5 2.1 0.6 0.9 1.8 1.8 1.1 1.7 -0.7 0.9 1.6 1.2 1.4 1.4 1.5 0.5 0.4 1.2 1.8 1.4 2.9 1.1 1.4 1.4 1.2 1.5 1.5 1.7 1.2 1.6 0.8 1.4 1.0 1.9 1.3 1.4
Taking other prescription medications 0.3 0.4 1.6 -0.9 0.3 -0.2 0.3 -0.3 1.1 1.0 -0.2 -1.3 0.8 0.4 0.1 0.7 0.0 -1.1 0.9 0.5 0.8 0.6 0.6 0.4 0.4 1.1 0.7 0.5 0.1 -0.4 -0.7 0.6 0.4 -0.1 0.0 -1.0 -0.1 0.4 0.1 -0.6 0.6 0.6 1.1 0.7 0.6
Age when periods started (menarche) 0.1 0.2 1.7 0.3 -0.2 0.3 -0.3 -0.1 -0.6 -0.5 0.9 1.3 -0.2 0.1 -0.2 -0.2 -0.4 0.6 -0.1 -0.1 -0.4 -0.1 -0.1 -0.4 0.8 0.5 -0.2 -0.3 -0.7 0.7 0.3 -0.1 -0.0 0.4 0.0 0.9 0.0 -0.4 0.1 0.6 -0.1 -0.7 -0.4 -0.2 -0.1
Bilateral oophorectomy (both ovaries removed) 0.1 0.2 1.0 0.7 0.3 0.5 0.3 -0.3 -0.2 -0.0 0.2 0.1 -0.3 -0.1 0.1 -0.1 -0.2 0.1 -0.1 0.1 0.0 -0.1 -0.1 -0.1 -0.9 0.2 -0.2 0.3 1.0 -0.5 0.5 -0.1 -0.0 -0.6 -0.6 -0.6 -0.6 -0.2 -0.5 -0.5 -0.2 0.9 0.2 -0.2 -0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 2.2 0.9 -1.1 -0.5 -1.1 0.7 -1.5 -1.3 -1.0 0.9 -1.2 -1.0 -1.0 -1.3 -1.4 1.4 -1.4 -1.0 -1.3 -1.1 -1.1 -1.0 -0.7 -0.9 -1.3 -1.1 -0.8 0.3 0.7 -1.1 -1.0 -1.4 -1.1 -0.9 -1.0 -1.0 -1.0 -1.5 -1.1 -1.1 -0.6 -1.3 -1.1
Tinnitus: Yes, but not now, but have in the past 1.6 1.7 5.4 1.2 -1.1 -1.6 -0.7 -0.3 -1.8 -1.3 -0.9 2.1 -1.5 -1.1 -2.0 -1.2 0.1 -0.1 -1.2 -1.0 -1.9 -0.9 -0.9 -1.2 -1.5 -0.0 -1.3 -1.6 -0.7 -1.4 1.0 -0.9 -0.8 -1.3 -2.0 -2.3 -2.0 -1.7 -1.7 -1.0 -1.0 -0.6 -1.1 -1.3 -0.9
Qualifications: CSEs or equivalent 1.5 2.0 5.4 0.5 1.9 0.8 1.3 0.5 0.9 1.4 1.4 -0.8 1.1 1.6 1.4 1.6 2.1 -1.5 1.1 2.1 1.2 1.5 1.5 1.2 0.8 0.4 1.5 1.6 2.0 0.7 0.6 1.5 2.2 1.3 1.5 1.4 1.5 1.4 1.4 1.7 1.5 2.3 0.5 1.4 1.5
Serious illness, injury or assault to yourself 2.5 3.0 8.1 -1.4 -2.2 -1.4 -2.3 -1.5 -0.3 -1.3 -1.6 1.1 -1.0 -2.0 -1.5 -1.7 -2.3 2.4 -1.2 -2.2 -1.1 -1.9 -1.9 -1.6 0.2 -1.1 -1.6 -1.4 -2.9 -1.1 -1.7 -1.9 -2.2 -1.9 -1.6 -2.0 -1.8 -1.5 -1.8 -2.1 -1.9 -2.4 -1.1 -1.6 -1.9
High blood pressure 0.4 1.1 5.6 0.0 -1.0 -1.7 -0.2 -0.3 -1.3 -1.1 -1.6 1.1 -0.6 -0.6 -2.2 -0.4 -0.9 -0.5 -0.9 -0.8 -2.0 -0.2 -0.2 -0.7 -0.3 0.2 -0.5 -1.8 -2.4 -1.1 0.1 -0.2 -0.6 -0.7 -0.7 -2.1 -0.5 -1.0 -0.9 -0.5 -0.2 -1.8 -0.9 -0.6 -0.2
Hayfever, allergic rhinitis or eczema 0.3 0.7 3.9 0.2 0.7 -1.6 0.4 0.8 -0.2 0.4 -0.2 -1.3 0.4 0.8 -0.6 0.8 0.1 -1.1 0.4 0.8 -0.3 1.0 1.0 1.3 1.2 1.5 0.6 -0.3 -0.5 1.0 0.2 1.0 0.8 1.2 0.6 0.4 1.0 0.4 0.8 2.0 0.9 0.2 -0.9 0.7 1.0
Multivitamins +/- minerals 0.4 0.5 6.4 0.7 0.4 0.6 0.1 -0.7 -0.1 0.1 0.8 1.1 -0.4 -0.0 -0.0 0.1 0.6 0.5 -0.0 0.1 0.1 0.0 0.0 0.2 -0.1 -0.2 0.0 0.3 1.2 0.9 0.8 0.0 0.2 1.0 0.3 2.5 -0.1 0.8 0.7 1.6 0.1 1.1 -0.5 -0.1 0.0
Stomach or abdominal pain in last month 1.5 1.8 7.0 -0.2 1.5 -0.2 1.1 -0.3 1.3 1.7 1.5 1.7 1.5 1.5 2.0 1.4 1.1 -1.1 2.0 1.3 1.9 1.3 1.3 1.8 1.0 0.5 1.4 1.9 1.8 1.0 0.5 1.3 1.1 1.2 0.5 0.3 0.5 1.3 1.1 -0.3 1.3 1.4 2.7 1.5 1.3
Supplements: Glucosamine 3.1 4.1 8.6 1.1 2.7 1.9 2.7 1.4 0.8 1.9 2.9 -0.2 1.6 2.6 2.2 2.1 1.5 -1.7 1.7 2.4 1.7 2.3 2.3 2.5 0.5 1.6 2.1 2.1 2.7 0.5 1.5 2.3 2.1 2.0 2.2 2.2 2.5 1.6 2.3 1.6 2.3 2.0 2.2 2.1 2.3
Diverticular disease/diverticulitis (self-reported) 1.4 1.7 5.9 -0.1 -1.3 -2.1 -0.7 -0.6 -1.3 -1.5 -1.0 1.2 -1.0 -1.0 -2.4 -0.9 -2.3 -0.1 -1.2 -1.3 -2.0 -0.7 -0.7 -1.2 -1.3 -0.7 -0.9 -2.1 -2.4 -1.2 -0.3 -0.7 -1.0 -0.4 -1.6 -1.6 -0.8 -1.2 -1.5 0.3 -0.8 -1.8 -1.2 -1.0 -0.7
Medication: Atenolol 0.3 0.4 2.5 -0.8 -0.3 -0.1 0.1 0.6 0.3 0.1 0.2 -0.6 0.6 0.1 -0.1 0.3 0.7 -0.8 0.5 -0.4 0.0 0.2 0.2 0.3 0.1 0.6 0.4 0.0 -1.6 -0.6 -0.5 0.2 -0.5 -0.1 -0.6 -1.3 -0.4 -0.2 -0.7 -0.7 0.3 -1.2 1.6 0.2 0.2
Medication: Levothyroxine sodium 0.5 0.8 5.5 0.5 -0.6 1.2 -0.2 1.3 -1.4 -0.9 1.0 0.1 -0.5 -0.1 -0.6 -0.9 0.1 0.1 -0.5 -0.9 -1.1 -0.4 -0.4 -0.3 0.0 -1.3 -0.8 -0.7 -1.7 1.1 0.5 -0.4 -1.1 -0.6 -1.1 -1.1 -0.6 -1.2 -0.9 -1.1 -0.5 -2.3 1.3 -0.6 -0.4
Sitting height 0.8 5.8 10.7 -0.6 2.6 2.3 2.4 1.1 2.2 2.5 1.5 -1.7 2.6 2.5 3.0 2.7 2.3 -1.3 2.4 2.6 2.7 2.5 2.5 2.1 1.1 2.7 2.7 2.7 2.5 1.7 0.0 2.5 2.5 2.8 3.0 3.3 2.9 3.0 2.9 2.7 2.5 2.3 1.8 2.7 2.5
Chronic bronchitis/emphysema (father) 2.5 3.0 6.4 -0.8 -2.2 -1.2 -1.6 -0.5 -1.2 -2.2 -2.4 1.4 -1.2 -1.9 -2.4 -1.6 -1.9 1.2 -1.6 -2.2 -2.0 -1.7 -1.7 -2.1 -0.1 -1.1 -1.7 -2.4 -2.4 -0.7 -1.5 -1.7 -2.0 -1.4 -1.3 -1.9 -1.3 -1.6 -1.7 -1.0 -1.8 -2.0 -2.5 -1.6 -1.7
High blood pressure (mother) 0.4 0.6 1.3 -1.1 0.6 -0.5 0.7 -0.9 0.7 0.6 -0.6 -0.3 0.9 0.8 0.1 0.9 -0.5 -0.8 0.8 0.8 0.3 0.9 0.9 0.7 1.0 1.1 0.9 -0.1 -1.0 -0.7 -1.1 0.9 0.7 1.1 0.5 -0.6 0.9 0.6 0.7 0.9 0.9 -0.3 -0.3 0.9 0.9
Body mass index (BMI) 1.8 7.8 29.2 -0.3 -2.8 -4.1 -1.4 -1.8 -2.3 -3.1 -2.6 -0.3 -2.4 -2.6 -3.7 -2.5 -4.4 0.6 -2.7 -2.6 -3.3 -2.3 -2.3 -2.1 -1.6 -0.7 -2.4 -4.1 -3.3 -4.2 -1.0 -2.3 -2.6 -3.4 -2.6 -5.4 -2.8 -3.4 -3.2 -2.3 -2.3 -3.1 -2.8 -2.5 -2.3
Impedance of leg (left) 1.2 5.7 16.3 -0.4 2.2 3.8 1.1 1.5 2.1 2.6 2.4 1.4 2.5 2.3 3.3 2.3 3.5 -0.5 2.6 2.1 2.8 2.1 2.1 1.9 1.1 1.3 2.3 3.4 2.1 4.0 0.2 2.0 2.0 2.7 2.2 3.9 2.4 3.1 2.6 1.5 2.1 1.9 3.0 2.3 2.0
Leg predicted mass (left) 0.6 2.9 8.2 0.1 -1.6 -2.0 -0.6 -0.3 -1.7 -2.3 -1.5 -2.3 -1.5 -1.5 -2.4 -1.6 -2.6 0.6 -1.8 -1.6 -2.2 -1.3 -1.3 -1.6 -1.1 -0.1 -1.5 -2.9 -2.1 -2.6 -0.3 -1.3 -1.7 -1.7 -1.3 -2.6 -1.4 -2.1 -1.8 -0.5 -1.4 -2.2 -2.0 -1.5 -1.3
Trunk fat mass 1.4 5.8 24.4 -1.2 -2.7 -2.9 -1.4 -1.6 -1.5 -2.6 -2.4 -0.6 -1.4 -2.2 -2.8 -2.0 -3.7 1.1 -1.9 -2.5 -2.5 -1.9 -1.9 -2.1 -1.2 -0.4 -1.8 -3.5 -3.9 -3.5 -1.7 -1.9 -2.5 -2.8 -2.1 -4.9 -2.1 -2.7 -2.8 -2.2 -1.9 -3.8 -1.4 -1.9 -1.9
Waist circumference 1.7 6.3 22.6 -0.1 -2.6 -3.2 -1.1 -0.9 -2.4 -3.1 -1.7 -0.3 -2.2 -2.3 -3.2 -2.3 -3.6 0.5 -2.4 -2.5 -3.1 -2.1 -2.1 -2.4 -1.9 -0.6 -2.2 -4.0 -3.2 -3.4 -0.6 -2.1 -2.5 -3.0 -2.5 -4.8 -2.5 -3.1 -3.0 -2.1 -2.1 -3.4 -2.0 -2.3 -2.1
Number of incorrect matches in round 0.9 1.5 4.2 0.2 1.3 0.4 1.4 1.8 0.6 1.5 -0.3 -0.4 0.8 1.3 0.9 1.1 1.5 -1.5 0.8 1.5 0.9 1.4 1.3 1.3 1.3 0.8 1.0 1.5 1.2 0.7 0.9 1.4 1.7 1.0 1.8 1.0 1.6 1.2 2.1 0.6 1.2 1.5 0.3 1.2 1.4
Past tobacco smoking 0.6 1.2 4.2 -0.9 -1.0 -1.9 -1.7 -1.5 0.4 -0.4 -1.0 -0.4 -0.5 -1.1 -0.0 -0.9 -1.0 1.7 -0.6 -1.0 0.1 -1.3 -1.3 -0.3 0.1 -1.4 -0.9 -0.3 -0.9 -2.1 -1.4 -1.3 -1.1 -1.1 -0.6 -0.9 -1.1 -0.6 -1.1 -0.7 -1.3 -0.8 -1.5 -0.9 -1.3
Alcohol usually taken with meals 0.1 0.2 1.5 -0.2 -0.0 1.2 -0.2 0.9 0.2 -0.0 0.4 -0.8 -0.2 0.1 0.2 -0.3 0.7 -0.0 -0.5 -0.2 0.1 -0.0 -0.1 -0.0 0.4 0.1 -0.1 0.0 0.2 0.0 -0.2 -0.0 -0.4 -0.5 1.0 0.2 0.4 0.3 0.1 0.5 -0.2 -0.0 -0.1 0.1 -0.0
Nervous feelings 0.6 1.0 3.6 -0.7 1.1 0.5 0.4 -0.8 1.3 1.2 -0.1 0.4 1.3 0.8 1.2 1.3 1.0 -0.1 1.2 1.0 1.4 0.8 0.9 0.4 0.8 0.6 1.1 1.5 1.3 0.6 -0.7 0.8 1.1 1.1 1.1 1.4 1.0 1.2 1.0 1.5 0.9 1.9 -0.6 1.0 0.8
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.2 2.2 -1.2 -0.3 -0.4 -0.4 -0.0 0.5 -0.1 -1.3 0.1 0.5 -0.3 -0.1 0.1 -0.2 0.8 0.4 -0.3 -0.0 -0.1 -0.1 -0.1 1.0 0.2 0.1 -0.1 -0.9 0.3 -1.5 -0.1 -0.2 0.1 0.4 -0.2 -0.0 0.4 0.2 -0.1 -0.1 -0.5 -0.8 0.1 -0.1
Hearing difficulty/problems with background noise 0.2 0.3 2.3 0.6 0.0 1.5 -0.5 0.9 -0.4 -0.1 -0.4 -0.8 -0.3 -0.0 -0.4 -0.1 1.0 -0.5 0.0 0.0 -0.4 -0.0 -0.0 -0.7 0.1 -0.8 -0.1 0.2 0.7 0.7 0.5 -0.0 0.1 0.0 -0.6 0.3 -0.6 0.2 0.0 -0.7 0.0 0.6 0.5 -0.2 -0.0
Hair/balding pattern: Pattern 2 0.7 0.9 6.7 0.8 0.7 2.2 0.7 0.2 0.0 0.5 1.3 -0.0 0.3 0.5 1.0 0.7 1.3 0.8 0.3 0.9 0.5 0.4 0.5 0.3 -1.1 0.4 0.6 0.9 1.4 1.8 1.2 0.4 0.9 1.1 0.5 2.6 0.8 0.7 0.8 1.4 0.7 1.0 0.7 0.4 0.4
Had menopause 1.0 1.2 5.5 -1.0 0.8 1.1 1.1 -0.5 0.9 1.0 -0.5 1.7 1.1 1.0 -0.3 1.4 -0.0 -2.3 0.9 1.1 0.4 1.5 1.5 0.9 1.0 1.6 1.4 0.2 0.0 -0.9 -0.7 1.5 1.3 0.5 1.3 -1.0 1.2 0.9 1.1 0.2 1.4 1.0 0.6 1.4 1.5
Had other major operations 1.0 1.2 4.1 -0.1 -1.0 -2.0 -1.2 -1.1 -0.3 -0.9 -0.9 0.3 -0.6 -1.3 -0.8 -1.0 -0.6 0.9 -0.5 -1.4 -0.4 -1.1 -1.2 -1.3 -1.0 -0.3 -1.1 -0.6 -0.1 -1.5 -0.8 -1.1 -1.5 -1.4 -1.5 -1.8 -1.4 -0.9 -1.8 -1.4 -1.2 -0.2 -1.0 -1.0 -1.1
Forced vital capacity (FVC) 0.7 2.6 10.5 2.1 1.8 1.8 1.7 3.2 -0.8 0.5 2.9 -1.8 0.2 1.8 1.3 0.8 2.1 0.0 0.3 1.6 0.4 1.4 1.4 1.5 -0.1 0.7 0.8 0.9 2.0 2.0 2.3 1.4 1.3 1.8 1.4 3.1 2.1 0.9 1.6 2.2 1.3 1.1 1.1 1.0 1.4
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 1.3 1.0 -0.5 -0.0 -0.5 0.9 -1.1 -0.8 -0.5 0.3 -0.8 -0.4 -0.5 -0.8 -1.0 1.1 -0.9 -0.4 -0.9 -0.6 -0.6 -0.7 -0.5 -0.3 -0.8 -0.5 -0.2 0.7 0.8 -0.6 -0.5 -0.6 -0.6 -0.2 -0.5 -0.4 -0.4 -0.9 -0.6 -0.7 -0.3 -0.8 -0.6
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 3.0 -0.0 -0.0 -0.5 -0.2 -1.2 0.1 0.2 -1.7 0.9 -0.3 -0.2 -0.9 0.1 -0.3 -0.4 -0.1 0.0 -0.2 0.0 0.0 0.1 0.8 -0.2 0.0 -0.1 0.4 -1.0 -0.2 0.0 0.0 -0.3 -0.4 -0.6 -0.5 0.3 -0.4 -0.3 0.0 0.9 -0.4 -0.1 0.0
Qualifications: None of the above 0.7 1.5 11.8 -0.7 -1.0 -2.5 -0.6 -3.4 -0.3 -0.6 -2.4 1.6 -0.5 -1.0 -1.6 -0.4 -1.9 -0.2 -0.5 -0.5 -1.0 -0.7 -0.6 -0.2 0.4 -0.2 -0.5 -1.3 -1.5 -2.2 -0.6 -0.7 -0.1 -1.1 -1.1 -2.1 -1.4 -0.5 -1.0 -1.3 -0.6 -0.6 -1.1 -0.8 -0.7
Financial difficulties in last 2 years 0.2 0.3 2.2 -1.1 -0.1 0.8 -0.6 -0.8 0.7 0.2 -0.8 0.3 0.7 0.1 0.2 0.5 -0.1 -0.3 0.7 0.2 0.4 0.1 0.2 -0.0 0.9 0.2 0.4 -0.2 -0.6 -1.5 -1.2 0.2 0.3 0.0 -0.2 -1.3 -0.2 0.1 -0.5 0.1 0.2 -0.0 -0.0 0.3 0.1
Mouth/teeth dental problems 0.4 0.6 1.5 1.0 -0.3 1.2 -0.5 0.8 -1.1 -0.9 1.1 -0.5 -1.0 -0.6 0.4 -1.0 -0.5 0.5 -0.7 -0.5 -0.4 -0.9 -0.9 -0.9 -1.2 -1.2 -1.0 -0.2 0.8 0.2 0.9 -0.9 -0.6 -0.5 -1.0 0.5 -0.9 -0.7 -0.7 -0.7 -0.9 -0.1 -0.1 -0.9 -0.9
Heart attack 0.6 0.8 4.3 -2.1 -0.4 -0.1 -0.1 -0.9 1.3 0.5 -1.1 0.8 1.4 0.0 0.4 0.4 0.6 0.2 1.3 -0.3 0.7 0.1 0.1 0.3 1.8 0.4 0.6 0.5 -2.1 -0.8 -2.0 0.1 -0.3 0.5 -0.4 -1.3 -0.4 0.5 -0.3 -0.3 0.2 -1.3 1.0 0.5 0.1
Allergy 0.2 0.4 2.7 -0.9 0.1 0.7 -0.5 -1.6 1.1 0.4 0.4 0.9 0.4 -0.1 1.1 0.1 -0.1 0.6 0.4 -0.1 1.1 -0.3 -0.3 -0.3 -0.2 -0.4 0.1 0.8 0.7 -1.1 -1.0 -0.3 -0.2 -0.2 0.2 0.2 -0.1 0.4 -0.1 -0.2 -0.3 0.6 0.2 0.1 -0.3
Pain all over the body in last month 0.6 0.7 5.1 0.1 0.8 -0.3 0.9 -1.4 0.3 0.7 0.3 2.2 0.4 0.7 -0.5 0.7 -0.4 -1.6 0.3 1.0 -0.2 0.9 0.9 1.3 0.7 1.2 0.7 0.3 0.1 -0.9 0.3 0.9 1.0 0.4 0.8 -0.6 0.6 0.3 0.6 0.6 0.9 0.9 -0.4 0.6 0.9
Diabetes (self-reported) 1.6 2.4 6.0 -0.4 -1.8 -2.4 -1.6 -0.8 -1.0 -1.6 -1.6 -0.3 -1.1 -1.7 -1.8 -1.5 -1.9 0.9 -1.4 -1.9 -1.5 -1.5 -1.5 -1.5 -0.2 -1.2 -1.4 -2.0 -2.2 -1.6 -0.6 -1.5 -1.8 -1.9 -1.4 -2.3 -1.5 -1.7 -1.6 -1.4 -1.5 -2.2 -1.4 -1.5 -1.5
Hayfever/allergic rhinitis (self-reported) 0.8 1.1 4.0 0.2 0.9 -1.3 1.4 0.5 0.0 0.3 -0.2 -2.0 0.6 1.1 -0.5 1.1 1.2 -1.8 0.5 1.2 -0.2 1.5 1.4 1.2 1.1 0.3 1.1 -0.5 -0.0 0.4 0.5 1.5 1.4 1.1 0.8 0.3 1.3 1.0 0.9 1.4 1.4 0.6 0.5 1.1 1.5
Medication: Ramipril 4.0 5.1 13.4 -0.4 -2.7 -3.4 -2.3 0.6 -1.7 -2.5 -1.9 -1.0 -1.6 -2.3 -2.0 -2.4 -3.3 2.5 -2.1 -3.0 -2.0 -2.3 -2.3 -2.2 -0.3 -1.6 -2.3 -2.8 -3.5 -1.8 -0.9 -2.3 -3.0 -2.0 -1.8 -2.4 -1.5 -2.4 -2.4 -1.5 -2.3 -3.7 -2.3 -2.1 -2.3
Medication: Simvastatin 0.2 0.2 2.7 -0.1 0.2 -0.5 0.0 -0.3 -0.0 0.3 -0.3 0.9 0.6 0.4 -0.0 0.5 -0.1 -0.6 0.3 0.1 -0.0 0.4 0.5 0.6 0.6 0.4 0.5 0.0 -0.5 -0.4 0.3 0.4 0.1 -0.5 0.3 -1.6 0.1 -0.4 0.3 -0.8 0.6 -0.6 0.7 0.3 0.4
Fluid intelligence score 0.4 0.9 6.0 0.6 1.0 1.9 0.6 1.1 0.3 0.7 2.4 0.2 0.5 0.8 1.6 0.5 1.3 0.3 0.6 0.6 1.2 0.5 0.5 0.4 -1.1 -0.1 0.4 1.2 1.7 0.9 0.7 0.5 0.2 0.7 0.5 1.6 1.0 0.5 0.6 0.7 0.5 0.9 1.3 0.6 0.5
Illnesses of siblings 1.3 1.8 5.1 -0.1 1.5 1.0 1.1 0.8 1.2 1.5 1.4 0.1 1.1 1.3 1.9 1.1 2.2 -0.7 1.3 1.7 1.6 1.1 1.1 1.5 0.6 0.3 1.1 1.9 1.6 1.6 0.1 1.2 1.7 1.7 1.5 2.2 1.4 1.5 1.8 1.5 1.0 1.6 0.3 1.3 1.2
Neuroticism score 0.7 1.5 7.3 -1.1 -1.3 -1.5 -1.2 -1.3 -0.2 -1.2 -2.7 0.1 -0.2 -1.3 -2.0 -0.5 -1.4 0.9 -0.5 -1.4 -1.2 -0.8 -0.8 -1.2 -0.5 -0.7 -0.5 -1.4 -2.3 -0.9 -1.7 -0.8 -1.2 -0.9 -0.9 -2.1 -1.1 -0.7 -1.2 -0.0 -0.7 -1.1 -2.3 -0.8 -0.8
Weight 0.8 3.9 14.1 -0.3 -2.0 -2.6 -0.8 -0.9 -1.8 -2.4 -1.7 -1.3 -1.6 -1.7 -2.7 -1.7 -3.3 0.6 -2.0 -1.9 -2.5 -1.5 -1.5 -1.5 -1.3 0.0 -1.6 -3.3 -2.6 -3.2 -0.7 -1.5 -1.9 -2.2 -1.5 -3.8 -1.6 -2.3 -2.1 -1.1 -1.5 -2.7 -1.9 -1.6 -1.4
Impedance of arm (right) 0.2 0.9 2.6 -0.9 0.5 1.4 0.2 -0.1 1.4 1.3 0.7 1.1 1.3 0.7 1.4 0.8 1.6 0.9 1.2 0.5 1.5 0.7 0.6 0.7 1.1 0.2 0.9 1.6 0.1 0.8 -0.6 0.7 0.4 0.8 0.9 1.4 1.0 1.1 0.7 0.4 0.6 0.2 1.6 1.0 0.7
Arm fat percentage (right) 2.4 9.4 33.9 -1.2 -3.4 -3.9 -2.0 -2.5 -1.9 -3.1 -3.1 0.1 -2.2 -3.0 -3.6 -2.7 -4.6 1.5 -2.6 -3.1 -3.1 -2.7 -2.7 -2.8 -1.4 -1.2 -2.6 -4.2 -4.2 -4.7 -1.9 -2.7 -3.0 -3.7 -2.9 -5.8 -3.0 -3.4 -3.7 -2.7 -2.8 -3.9 -2.6 -2.6 -2.7
Trunk fat-free mass 0.2 1.1 6.5 0.6 -0.8 -0.4 -0.2 1.0 -1.5 -1.6 -0.3 -2.5 -1.1 -0.8 -1.3 -1.0 -1.3 0.3 -1.3 -1.0 -1.4 -0.8 -0.7 -1.1 -1.0 0.1 -0.9 -1.9 -0.7 -0.8 0.4 -0.7 -1.0 -0.7 -0.5 -0.7 -0.6 -1.2 -0.9 0.3 -0.7 -1.2 -1.4 -1.0 -0.8
Hip circumference 0.7 2.8 11.0 -0.3 -1.6 -1.8 -0.4 -0.4 -1.5 -2.1 -1.3 -2.2 -1.3 -1.4 -2.3 -1.4 -2.7 0.0 -1.5 -1.5 -2.1 -1.2 -1.2 -1.5 -1.1 0.5 -1.3 -2.8 -2.3 -2.5 -0.7 -1.2 -1.5 -1.8 -1.3 -3.3 -1.5 -2.1 -1.9 -0.4 -1.2 -2.2 -1.9 -1.3 -1.2
Time employed in main current job 0.3 0.3 3.1 -0.2 0.5 0.4 0.3 -0.5 0.6 0.7 -0.5 0.7 -0.1 0.1 0.2 0.2 0.3 -0.5 0.0 0.6 0.4 0.1 0.1 0.6 0.9 -0.7 0.1 0.7 1.3 -0.1 -0.4 0.1 0.8 0.0 0.4 0.7 0.2 0.6 0.6 0.0 0.0 1.8 -0.7 0.1 0.1
Alcohol intake versus 10 years previously 1.2 1.9 11.8 -2.2 1.0 -0.9 0.6 -1.0 2.3 1.7 -1.0 -0.7 1.7 1.1 1.3 1.4 1.2 -0.7 1.7 0.9 2.0 1.1 1.1 1.5 3.4 1.6 1.5 1.3 0.2 -0.8 -1.8 1.1 0.9 1.0 1.7 0.1 0.9 1.6 1.0 1.2 1.0 1.0 0.3 1.5 1.1
Father’s age at death 0.9 1.3 8.3 1.9 1.3 0.2 1.7 0.8 -1.0 0.4 2.9 0.1 -0.0 1.2 0.5 0.5 1.1 -1.7 0.4 1.2 0.0 1.2 1.2 1.1 -1.8 0.0 0.4 0.2 1.3 0.1 2.5 1.2 1.1 1.1 -0.2 0.9 0.7 -0.1 0.7 0.6 1.1 0.5 1.7 0.8 1.2
Worrier / anxious feelings 0.5 0.9 5.2 0.5 -0.6 -1.1 -0.7 -1.4 -0.8 -0.5 -1.6 0.0 -1.1 -1.0 -1.6 -0.7 -1.2 0.6 -1.2 -0.8 -1.1 -0.8 -0.8 -0.6 -0.9 -0.5 -0.9 -0.7 -0.3 -0.4 0.3 -0.8 -0.8 -1.0 -0.8 -0.6 -0.9 -0.8 -0.7 -0.3 -0.8 0.3 -2.3 -1.1 -0.8
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 2.9 -1.4 -0.6 -1.6 -0.6 -1.7 0.5 -0.2 -1.2 0.4 0.2 -0.5 -0.1 -0.4 -1.4 1.2 0.1 -0.5 0.1 -0.5 -0.5 0.4 0.7 0.2 -0.4 -0.4 -1.4 -1.6 -1.7 -0.5 -0.6 -0.7 0.0 -1.5 -0.4 -0.4 -0.5 -0.9 -0.6 -1.0 -0.9 -0.2 -0.5
Falls in the last year 0.8 1.1 5.5 -2.2 0.5 0.8 -0.1 -0.6 1.6 0.9 -0.4 -0.3 1.4 0.6 0.9 1.0 0.7 0.0 1.3 0.4 1.2 0.9 0.8 0.5 0.9 1.3 1.1 0.9 -0.2 0.3 -2.4 0.9 0.4 1.4 1.4 1.3 1.4 1.7 1.1 1.7 0.7 0.4 0.1 1.2 0.9
Hair/balding pattern: Pattern 3 1.0 1.4 3.0 0.2 1.5 0.4 1.2 1.6 0.6 1.3 1.1 0.4 1.3 1.7 1.2 1.2 1.4 -1.5 1.4 1.2 0.8 1.4 1.5 1.6 1.2 1.2 1.3 1.6 1.0 0.9 0.9 1.4 1.0 1.2 1.0 0.3 1.1 1.1 1.0 0.9 1.5 0.7 1.7 1.3 1.4
Number of live births 2.8 4.0 9.6 0.9 -2.2 -1.8 -1.6 -0.8 -2.1 -2.5 -1.7 1.3 -1.8 -2.0 -2.7 -2.0 -2.1 0.9 -1.8 -2.4 -2.5 -1.9 -1.8 -1.6 -1.2 -1.5 -1.9 -2.6 -2.1 -1.9 0.7 -1.9 -2.3 -2.1 -2.7 -3.1 -2.5 -2.5 -2.7 -1.7 -1.7 -2.3 -0.8 -2.2 -1.9
Forced expiratory volume in 1-second (FEV1) 0.4 1.4 7.8 1.8 1.2 1.4 1.1 2.8 -0.9 0.2 2.0 -1.8 -0.0 1.2 1.0 0.4 1.7 0.4 0.1 1.0 0.1 1.0 0.9 1.2 -0.3 0.6 0.4 0.7 1.1 1.5 1.9 1.0 0.8 1.3 1.0 2.4 1.5 0.6 1.1 1.6 0.9 0.3 0.9 0.6 1.0
Pulse rate 0.4 0.7 3.0 -0.9 0.5 1.7 0.5 -0.2 1.0 1.0 -0.5 1.4 0.8 0.6 0.4 0.9 0.4 -0.5 0.5 0.6 0.5 0.7 0.8 0.7 0.3 1.2 1.0 1.0 0.1 1.1 -0.7 0.7 0.7 0.8 1.3 0.9 1.0 1.2 0.9 0.6 0.8 0.5 0.4 0.7 0.7
Happiness 1.2 1.5 4.2 -0.5 1.1 0.9 1.3 0.9 0.9 0.7 -0.0 -2.0 1.3 1.2 0.2 1.6 1.3 -1.3 0.9 1.6 0.5 1.6 1.6 0.7 1.7 1.2 1.7 0.3 -0.2 -0.0 -0.7 1.6 1.8 0.7 2.1 0.1 1.7 1.1 1.1 1.5 1.6 0.8 0.2 1.4 1.6
Noisy workplace 0.4 0.4 3.1 -0.8 -0.1 -0.2 0.6 -0.6 0.4 -0.1 -1.6 -1.2 0.8 0.1 -0.9 0.8 -0.4 -0.7 0.5 0.1 -0.2 0.4 0.5 0.2 1.3 1.8 0.7 -0.3 -1.4 -0.2 -0.9 0.4 0.3 0.0 0.0 -0.7 0.0 0.3 0.1 0.2 0.6 -0.1 -0.1 0.3 0.4
Qualifications: A levels/AS levels or equivalent 2.0 4.4 10.2 0.4 2.5 2.6 2.0 1.2 1.5 2.3 3.1 -0.4 1.8 2.3 3.1 2.0 3.2 -1.1 2.0 2.3 2.5 2.0 2.0 2.1 0.4 1.2 2.0 2.7 2.9 1.9 0.9 1.9 2.0 2.0 1.9 2.9 2.2 2.0 2.1 1.6 2.0 2.2 2.5 2.1 1.9
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 2.7 0.1 0.8 0.9 0.5 0.1 0.6 1.2 0.9 1.6 0.5 0.9 0.9 0.5 1.1 -0.5 0.7 0.8 0.7 0.8 0.8 0.8 -0.2 0.7 0.6 1.3 0.5 1.3 0.4 0.8 0.7 1.1 1.0 1.1 0.9 0.7 1.1 0.7 0.7 0.5 0.8 0.8 0.8
Mouth/teeth dental problems: Dentures 0.9 1.5 8.9 -2.9 -1.1 -1.2 -1.1 -2.6 1.9 0.3 -2.6 0.9 1.1 -0.9 -0.1 0.0 -0.6 0.6 0.8 -1.3 0.7 -0.7 -0.6 -0.4 1.4 0.4 0.2 0.3 -1.7 -0.9 -3.0 -0.7 -1.2 -0.7 -0.1 -1.7 -1.1 0.4 -0.7 -1.1 -0.5 -1.1 0.0 -0.0 -0.7
Asthma 0.1 0.1 1.1 0.5 -0.1 0.8 0.6 1.1 -0.4 -0.1 -0.6 -0.5 0.0 -0.0 0.0 -0.1 0.3 -0.0 0.2 0.1 -0.1 0.1 0.1 0.1 -0.1 -0.0 -0.1 0.2 -0.1 0.7 0.9 0.1 0.2 0.1 0.0 -0.1 -0.1 -0.2 0.3 -0.8 0.1 -0.2 0.4 0.0 0.1
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.6 2.1 -0.6 0.6 -0.0 -0.0 -0.4 0.9 0.7 -0.8 0.2 0.9 0.5 0.1 1.0 0.0 -0.9 1.0 0.8 0.5 0.7 0.7 0.9 0.6 1.2 0.8 0.3 -0.4 0.3 -0.9 0.7 1.0 1.3 0.4 0.6 0.5 1.1 0.9 1.4 0.7 0.6 -0.8 0.7 0.7
Medication: Cholesterol lowering 0.5 0.7 4.5 -2.1 -0.5 0.4 -1.1 -1.3 1.4 0.7 -1.4 1.4 1.1 -0.1 0.3 0.3 -0.0 0.3 0.7 -0.3 0.7 0.1 0.1 -0.0 0.9 -0.6 0.5 0.4 -1.7 0.2 -1.7 0.1 -0.3 -0.2 0.0 -1.3 0.1 0.4 -0.1 -1.0 0.2 -1.2 1.3 0.4 0.1
Depression (self-reported) 1.0 1.1 3.3 -1.0 -1.2 -1.6 -0.2 -1.5 -0.4 -1.1 -1.6 0.5 -0.8 -1.1 -1.5 -0.8 -1.4 0.4 -0.8 -1.1 -1.1 -0.8 -0.8 -1.0 -0.0 -0.5 -0.7 -1.8 -1.7 -1.5 -1.6 -0.8 -0.9 -0.7 -0.8 -1.4 -0.9 -0.4 -1.0 -0.2 -0.9 -1.1 -1.4 -0.8 -0.9
Medication: Lansoprazole 4.1 4.7 9.4 -1.8 2.1 2.3 1.8 -0.7 3.0 3.0 1.0 -0.0 2.8 2.2 2.5 2.5 2.0 -1.9 2.8 1.9 2.9 2.2 2.2 1.8 1.9 2.6 2.6 3.1 1.2 1.6 -1.1 2.2 1.7 2.0 2.1 1.5 2.2 2.6 2.2 1.6 2.2 1.9 2.6 2.6 2.2
Prospective memory result 0.6 0.8 3.8 0.2 -1.0 -0.2 -0.3 1.0 -0.8 -1.2 -0.6 -1.4 -0.4 -0.8 -0.7 -0.7 -0.6 0.3 -0.7 -1.0 -0.8 -0.8 -0.7 -0.4 0.5 -1.2 -0.6 -0.7 -0.6 -0.9 0.4 -0.8 -1.0 -1.4 -0.9 -1.3 -0.9 -0.8 -0.9 -1.9 -0.6 -1.0 0.8 -0.8 -0.8
Lung cancer (father) 0.6 0.7 5.5 -1.9 -0.8 0.9 -1.2 0.2 1.2 0.0 -1.4 -0.7 0.5 -0.6 0.6 -0.3 -0.2 1.6 0.2 -0.9 0.8 -0.6 -0.7 -1.1 1.2 0.5 -0.2 0.4 -1.0 0.9 -2.4 -0.6 -0.9 -0.2 0.7 0.4 0.2 0.5 0.1 -0.1 -0.7 -0.8 -0.5 -0.1 -0.7
Illnesses of mother 0.2 0.3 2.7 0.9 -0.0 0.3 -0.4 1.6 -0.4 -0.4 1.1 -1.1 -0.2 -0.2 0.5 -0.2 0.9 0.2 -0.2 -0.3 0.2 -0.3 -0.3 -0.7 -0.4 -1.1 -0.2 0.3 1.0 0.5 0.7 -0.3 -0.3 -0.2 -0.3 0.4 -0.3 -0.3 -0.3 -0.3 -0.2 0.2 0.3 -0.3 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.7 2.4 7.0 1.9 2.0 1.3 1.7 2.6 -0.3 0.9 2.6 -1.4 0.5 1.9 1.4 1.1 2.2 -0.5 0.6 1.8 0.5 1.6 1.6 1.8 -0.1 0.8 1.1 1.4 2.0 1.6 2.0 1.6 1.5 1.6 1.3 2.3 1.7 1.0 1.5 1.6 1.5 1.3 1.3 1.2 1.6
Pulse wave Arterial Stiffness index 0.8 0.9 3.5 0.9 -0.9 -1.7 0.2 -0.7 -1.2 -0.9 -0.7 0.9 -1.4 -1.0 -1.1 -1.0 -1.1 0.7 -1.3 -0.7 -1.0 -0.8 -0.8 -0.7 -1.9 -0.6 -1.0 -1.1 0.0 -0.6 1.1 -0.8 -0.6 -1.1 -1.1 -0.6 -1.0 -1.0 -1.0 -0.7 -0.8 -0.4 -0.4 -1.0 -0.8
Impedance of arm (left) 0.3 1.6 5.2 -0.6 0.9 2.1 0.8 0.6 1.3 1.4 1.1 1.1 1.4 1.1 1.6 1.1 2.1 0.3 1.5 0.8 1.5 1.1 1.1 1.0 1.1 0.7 1.2 1.8 0.4 1.6 -0.1 1.1 0.8 1.5 1.1 2.1 1.4 1.6 1.3 0.8 1.1 0.4 2.3 1.3 1.1
Arm fat mass (right) 2.0 8.3 27.5 -0.5 -3.1 -3.6 -1.6 -1.7 -2.4 -3.3 -2.7 -0.9 -2.4 -2.8 -3.8 -2.6 -4.5 1.1 -2.8 -2.9 -3.3 -2.4 -2.5 -2.6 -1.7 -0.8 -2.5 -4.3 -3.7 -4.4 -1.1 -2.5 -2.9 -3.3 -2.6 -5.2 -2.8 -3.4 -3.3 -2.2 -2.5 -3.6 -2.8 -2.6 -2.4
Trunk predicted mass 0.2 1.1 6.1 0.6 -0.8 -0.4 -0.3 1.0 -1.4 -1.6 -0.3 -2.5 -1.1 -0.8 -1.3 -1.0 -1.4 0.3 -1.3 -1.0 -1.5 -0.8 -0.8 -1.1 -0.9 -0.0 -0.9 -1.9 -0.6 -0.8 0.3 -0.8 -1.0 -0.8 -0.5 -0.7 -0.6 -1.2 -0.9 0.2 -0.8 -1.2 -1.4 -1.0 -0.8
Standing height 0.2 2.4 7.8 -0.2 1.3 2.7 1.3 2.0 0.8 1.0 1.6 -2.1 1.5 1.6 1.7 1.3 1.8 0.1 1.3 1.1 1.3 1.5 1.5 1.0 0.5 1.5 1.5 1.2 0.9 1.8 0.3 1.5 0.9 2.0 1.9 2.8 2.3 1.7 1.8 2.2 1.5 0.2 1.8 1.6 1.5
Length of working week for main job 0.3 0.3 1.5 -1.0 0.3 0.3 0.4 -0.4 0.8 0.4 -0.1 0.6 0.7 0.5 0.8 0.4 0.2 0.3 0.4 0.3 0.8 0.4 0.4 0.3 1.0 0.6 0.4 0.3 -0.3 -0.3 -0.9 0.5 0.3 0.6 1.0 0.8 1.2 0.7 0.7 0.5 0.3 -0.3 0.1 0.7 0.5
Exposure to tobacco smoke at home 2.2 2.4 7.9 -0.6 -1.7 -1.1 -1.3 -1.1 -0.8 -1.5 -2.8 -0.6 -1.0 -1.6 -2.2 -1.1 -2.6 0.8 -1.1 -1.5 -1.7 -1.2 -1.2 -1.7 -0.2 -1.9 -1.1 -2.2 -2.5 -2.2 -1.3 -1.2 -1.3 -1.6 -1.5 -2.6 -1.5 -1.1 -1.4 -1.7 -1.2 -1.9 -1.0 -1.2 -1.2
Breastfed as a baby 0.8 1.0 3.1 -0.7 0.8 1.5 0.6 -0.1 0.9 0.9 -0.3 -0.3 1.0 1.1 0.3 1.0 1.7 -0.8 0.9 0.7 0.6 1.1 1.1 0.8 1.8 0.6 1.1 0.7 0.3 0.3 -0.3 1.1 0.8 1.2 1.4 1.1 1.4 1.4 1.1 1.5 1.0 0.8 0.6 1.1 1.1
Tense / ‘highly strung’ 0.5 0.8 4.6 -0.4 -1.1 -1.0 -0.7 -0.5 -0.4 -0.9 -2.0 -0.3 -0.3 -1.1 -1.4 -0.5 -1.4 0.3 -0.5 -1.0 -0.9 -0.5 -0.5 -1.2 -0.8 -0.5 -0.5 -1.2 -2.1 -0.4 -0.8 -0.5 -0.8 -0.5 -0.8 -1.3 -0.6 -0.6 -0.8 -0.5 -0.5 -1.4 -1.2 -0.6 -0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 1.2 1.8 5.0 -0.1 -1.5 -1.6 -0.6 -0.8 -1.3 -1.6 -1.7 -0.4 -1.2 -1.4 -2.2 -1.1 -1.8 1.1 -1.7 -1.5 -1.9 -1.1 -1.1 -1.4 -1.0 -0.0 -1.1 -1.9 -2.0 -1.1 -0.3 -1.1 -1.4 -1.5 -0.9 -1.7 -0.8 -1.3 -1.4 -0.6 -1.0 -1.4 -1.9 -1.3 -1.1
Hair/balding pattern: Pattern 4 1.0 2.4 4.4 0.3 -1.6 -1.9 -1.2 -1.2 -1.2 -1.5 -2.1 -1.2 -1.4 -1.7 -1.6 -1.7 -1.8 0.5 -1.5 -1.6 -1.4 -1.5 -1.6 -1.8 -1.8 -0.8 -1.8 -1.8 -1.5 -1.6 -0.4 -1.5 -1.5 -1.7 -1.7 -2.1 -1.5 -1.7 -1.7 -1.4 -1.7 -1.4 -1.9 -1.5 -1.5
Birth weight of first child 0.3 0.5 4.6 1.3 0.5 -1.1 -0.4 -0.0 -0.4 -0.1 0.5 -0.5 -0.7 -0.1 -0.4 0.0 0.2 -0.5 -0.6 0.3 -0.4 -0.2 -0.1 -0.4 -0.9 -0.7 -0.1 -0.3 2.1 -1.4 1.2 -0.2 0.2 -0.3 -0.5 0.2 -0.4 -0.4 -0.4 0.5 -0.0 1.8 -1.1 -0.4 -0.2
Peak expiratory flow (PEF) 0.1 0.3 4.6 -0.1 0.1 0.1 0.0 0.9 -0.0 -0.1 -0.5 -2.1 0.4 0.3 0.7 0.0 0.5 0.9 0.2 -0.1 0.4 0.3 0.2 0.7 0.2 -0.3 0.1 0.1 -0.8 0.3 -0.1 0.2 -0.3 0.0 0.7 0.3 0.7 0.3 0.5 -0.3 0.2 -1.1 1.0 0.4 0.3
Pulse wave reflection index 0.2 0.3 1.3 0.9 -0.3 -1.2 0.5 0.3 -0.8 -0.5 -0.4 0.7 -0.7 -0.3 -0.3 -0.7 -0.1 0.3 -0.5 -0.6 -0.4 -0.4 -0.4 -0.3 -0.7 0.2 -0.7 -0.2 0.4 -0.4 1.0 -0.4 -0.6 -0.5 0.0 -0.3 -0.4 -0.7 -0.1 -0.5 -0.5 -0.0 -0.7 -0.5 -0.4
Ever highly irritable/argumentative for 2 days 0.4 0.5 3.0 0.0 -0.7 -0.2 -1.6 0.8 0.1 -0.3 -1.1 -1.7 -0.4 -0.9 -0.2 -0.5 0.3 0.9 -0.6 -0.7 0.1 -0.8 -0.7 -1.0 -0.1 -0.7 -0.6 0.0 -0.0 -0.1 -0.2 -0.8 -0.6 -0.9 -0.4 -0.1 -0.6 -0.2 -0.7 -0.6 -0.7 0.3 -1.0 -0.6 -0.8
Loud music exposure frequency 0.6 0.6 3.4 0.3 -0.6 -0.8 -0.6 -1.2 -0.6 -0.6 -0.4 -0.5 -0.6 -0.7 -1.2 -0.5 -1.5 0.2 -0.7 -0.5 -0.8 -0.5 -0.5 -0.6 -0.6 0.1 -0.6 -1.0 -1.1 -1.8 -0.1 -0.5 -0.5 -0.7 -1.3 -1.2 -0.8 -1.0 -1.1 -0.6 -0.5 -0.5 -1.0 -0.6 -0.5
Qualifications: O levels/GCSEs or equivalent 4.2 6.7 12.7 -0.4 2.9 3.3 2.5 2.1 1.9 2.6 3.3 -1.1 2.5 2.9 3.4 2.6 3.6 -2.3 2.5 2.9 2.7 2.6 2.6 2.2 1.1 2.2 2.6 2.9 2.3 2.6 0.2 2.6 2.7 2.8 2.9 2.9 2.9 2.5 2.8 2.8 2.6 2.0 2.9 2.7 2.6
Mouth/teeth dental problems: Bleeding gums 1.3 1.6 4.0 1.6 1.4 0.4 1.9 1.9 -0.3 0.7 1.1 0.3 0.4 1.4 0.0 1.1 1.1 -1.2 0.2 1.8 -0.1 1.6 1.6 1.5 0.1 1.7 1.1 0.5 0.7 0.6 1.7 1.6 1.8 1.4 1.6 1.6 2.0 0.6 1.6 1.6 1.5 1.1 0.1 1.0 1.6
Blood clot in the leg (DVT) 1.3 1.7 6.2 -0.2 -1.2 -0.9 -1.0 -1.4 -0.8 -1.1 -1.2 1.3 -1.0 -1.2 -1.5 -1.0 -1.7 0.9 -1.1 -1.2 -1.3 -1.1 -1.1 -1.1 -0.5 -1.6 -1.0 -1.6 -1.3 -2.3 -0.6 -1.1 -1.2 -1.9 -1.3 -2.5 -1.2 -1.5 -1.4 -2.2 -1.0 -1.1 -1.0 -1.1 -1.1
Medication: Paracetamol 0.1 0.2 3.2 0.1 0.2 -0.2 -0.1 0.7 0.1 0.5 0.0 -0.2 -0.1 0.0 0.6 -0.1 0.2 0.5 -0.2 0.3 0.3 -0.1 -0.1 0.3 -0.9 0.6 -0.2 0.8 0.7 1.8 0.3 -0.1 0.3 0.0 0.2 0.5 0.3 0.4 0.3 -0.4 -0.2 0.5 -0.2 -0.1 -0.1
Headache pain in last month 0.6 1.1 3.4 -1.7 0.7 0.8 -0.2 -0.8 1.8 1.4 -0.5 0.2 1.6 0.7 1.5 1.3 1.3 -0.3 1.5 1.0 1.6 0.9 0.9 0.4 0.2 -0.2 1.3 1.2 -0.3 1.0 -1.6 0.9 1.1 0.8 1.0 0.3 0.9 1.3 1.0 0.1 1.0 0.3 1.1 1.2 0.9
Medication for cholesterol, blood pressure or diabetes 0.9 1.5 6.8 1.5 1.5 1.0 1.4 1.2 -0.1 0.3 2.3 -0.9 0.2 1.1 1.3 0.8 1.0 -0.4 0.6 1.4 0.7 0.8 0.8 1.4 0.8 1.1 0.6 0.9 2.5 1.2 1.2 0.8 1.3 1.4 0.9 2.6 0.8 0.8 1.2 1.8 0.8 2.0 -0.2 0.6 0.8
Glaucoma (self-reported) 0.3 0.3 2.0 0.4 0.6 0.0 0.7 0.2 0.0 0.3 0.0 -1.4 0.1 0.5 -0.3 0.7 0.3 -0.9 -0.2 0.6 -0.0 0.7 0.7 0.5 -0.3 0.3 0.7 -0.1 0.4 -0.5 0.6 0.7 0.7 0.1 0.8 -0.0 0.9 0.2 0.4 1.2 0.8 0.8 -0.4 0.5 0.7
Gout (self-reported) 1.0 1.4 4.0 -0.5 1.3 1.5 1.2 0.9 1.0 1.2 1.6 1.1 1.2 1.2 1.4 1.3 1.2 -0.8 1.1 1.0 1.0 1.0 1.1 1.1 0.5 1.2 1.4 1.5 1.2 2.0 -0.0 1.0 0.8 1.1 1.3 1.6 0.9 1.5 1.2 0.6 1.3 0.9 1.8 1.1 1.0
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 5.0 1.7 -0.5 2.2 0.2 2.1 -2.2 -1.2 1.7 -0.4 -1.0 0.0 -1.0 -1.0 -0.0 0.3 -1.1 -0.7 -1.7 -0.3 -0.3 -0.2 -0.4 -1.0 -0.8 -1.0 -1.3 1.0 1.9 -0.3 -0.9 -0.6 -1.0 -0.5 -0.4 -1.4 -0.8 -0.7 -0.3 -2.1 1.3 -0.8 -0.3
Medication: Amlodipine 0.3 0.4 2.5 -0.8 -0.7 -1.1 -0.8 -0.4 -0.0 -0.1 -0.6 1.1 0.1 -0.4 -0.5 -0.3 -0.1 0.4 -0.2 -0.9 -0.3 -0.3 -0.3 0.0 0.8 0.1 -0.2 -0.1 -1.6 -0.0 -0.6 -0.4 -0.8 -0.7 -0.3 -1.4 -0.3 -0.6 -0.5 -1.4 -0.3 -1.4 0.4 -0.3 -0.3
Medication: Ventolin 100micrograms inhaler 1.5 2.0 6.7 -0.3 -1.9 -1.1 -1.1 -1.2 -1.0 -1.6 -2.6 1.6 -1.1 -1.8 -2.0 -1.1 -2.4 1.0 -1.4 -1.2 -1.6 -1.3 -1.2 -1.3 -1.3 -1.4 -1.1 -1.9 -2.0 -0.4 -0.5 -1.3 -0.7 -1.1 -1.3 -1.2 -1.1 -1.1 -1.3 -1.3 -1.2 -1.2 -1.5 -1.4 -1.3
Birth weight 0.8 1.7 11.1 3.1 0.3 1.4 0.6 3.1 -2.3 -0.9 1.8 -0.9 -1.3 0.2 -0.8 -0.5 0.3 -0.1 -1.1 -0.0 -1.4 0.1 0.1 -0.1 -2.0 -0.0 -0.5 -0.4 1.1 2.5 3.3 0.1 -0.1 0.7 -0.6 2.4 0.3 -0.5 0.2 1.4 0.2 0.2 0.3 -0.6 0.1
Chronic bronchitis/emphysema (mother) 2.5 2.9 7.1 -0.8 1.7 2.0 2.3 0.8 0.8 1.4 0.2 1.1 1.3 1.9 0.4 1.8 1.5 -2.1 1.2 2.1 0.4 2.1 2.1 1.6 1.9 2.7 1.9 1.0 0.3 1.5 -0.1 2.1 2.3 2.0 2.4 1.4 2.3 1.9 2.2 1.9 2.0 1.2 0.8 1.8 2.1
High blood pressure (siblings) 0.9 1.3 4.3 -0.2 -1.3 -0.9 -0.9 -1.4 -0.8 -1.1 -1.8 0.6 -0.6 -1.1 -1.4 -0.7 -2.1 0.7 -0.7 -1.2 -1.1 -0.9 -0.9 -1.3 -0.4 -0.2 -0.7 -1.5 -1.4 -1.3 -0.4 -0.9 -1.1 -1.2 -1.3 -2.0 -1.3 -1.1 -1.2 -1.2 -0.8 -1.3 -0.7 -0.9 -0.9
Forced vital capacity (FVC), Best measure 0.7 2.7 8.2 2.0 2.1 1.3 1.9 2.6 -0.3 1.0 2.9 -1.5 0.4 1.9 1.4 1.1 2.3 -0.5 0.6 1.9 0.7 1.6 1.6 1.8 0.1 0.6 1.1 1.4 2.5 1.4 2.2 1.6 1.6 1.6 1.4 2.8 1.9 1.1 1.6 1.8 1.5 1.8 1.4 1.2 1.6
Body fat percentage 1.3 5.2 24.1 -1.3 -2.5 -2.9 -1.2 -1.9 -1.4 -2.3 -2.2 0.2 -1.3 -2.0 -2.8 -1.8 -3.6 0.8 -1.7 -2.2 -2.3 -1.7 -1.7 -1.9 -1.2 -0.3 -1.7 -3.3 -3.7 -3.6 -1.7 -1.7 -2.2 -2.7 -2.1 -4.9 -2.0 -2.4 -2.6 -2.2 -1.7 -3.4 -1.2 -1.7 -1.7
Leg fat percentage (right) 1.2 4.3 17.5 -0.5 -2.1 -2.6 -1.3 -1.3 -1.6 -2.3 -1.6 -0.0 -1.6 -2.0 -2.5 -1.8 -3.4 0.4 -1.9 -1.8 -2.4 -1.7 -1.8 -1.9 -1.7 -0.4 -1.8 -3.0 -2.6 -2.9 -1.0 -1.7 -1.8 -2.6 -1.9 -4.2 -2.2 -2.3 -2.5 -2.0 -1.8 -2.5 -1.8 -1.8 -1.7
Arm fat-free mass (right) 0.1 0.8 4.5 0.3 -0.7 -0.5 0.1 0.6 -1.2 -1.5 -0.4 -2.1 -0.7 -0.6 -1.1 -0.7 -1.5 -0.1 -0.9 -0.8 -1.2 -0.5 -0.5 -0.8 -0.7 0.3 -0.6 -1.8 -0.8 -1.0 0.2 -0.5 -0.8 -0.6 -0.6 -1.1 -0.5 -1.0 -0.7 0.0 -0.5 -1.3 -0.8 -0.7 -0.5
Exposure to tobacco smoke outside home 0.6 0.8 3.2 -1.0 -1.1 -0.3 -1.2 -1.3 -0.0 -1.0 -1.8 -0.8 -0.2 -0.9 -1.5 -0.5 -1.0 0.0 -0.1 -0.8 -1.0 -0.5 -0.5 -1.4 -0.1 -0.1 -0.4 -1.4 -1.8 -1.5 -1.5 -0.5 -0.6 0.0 -0.7 -0.9 -0.9 -0.0 -0.8 0.3 -0.6 -0.8 -1.3 -0.4 -0.5
Comparative body size at age 10 0.3 0.8 4.4 0.1 -0.3 -2.1 -0.1 -0.4 -0.5 -0.6 -0.9 -0.8 -1.0 -0.6 -1.4 -0.3 -1.4 -0.8 -1.2 -0.2 -0.9 -0.3 -0.3 -0.3 -1.2 -0.9 -0.4 -1.3 -0.4 -1.4 -0.0 -0.3 -0.3 -1.3 -0.1 -2.0 -0.3 -1.1 -0.6 -0.0 -0.3 0.1 -1.8 -0.5 -0.3
Number of full brothers 0.3 0.4 1.9 -0.9 -0.5 -0.7 -1.0 0.1 0.6 0.1 -1.4 -0.7 0.1 -0.4 0.2 -0.2 0.4 0.9 -0.3 -0.2 0.3 -0.3 -0.3 0.2 1.1 -0.7 -0.1 0.2 -0.7 1.0 -1.2 -0.3 -0.1 -0.9 0.5 -0.7 0.1 0.2 0.1 -0.9 -0.4 -0.3 -0.4 -0.1 -0.3
Worry too long after embarrassment 0.2 0.3 2.5 0.6 0.4 -0.8 0.5 0.1 -0.0 0.1 -0.8 -0.3 -0.0 0.1 -0.6 0.4 0.9 -0.1 -0.1 0.3 -0.3 0.3 0.3 0.5 0.4 -0.0 0.3 0.4 0.3 0.5 0.6 0.3 0.5 0.2 0.0 0.4 0.0 0.4 -0.1 1.6 0.4 1.2 -1.1 0.0 0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.3 1.2 -0.7 0.4 -0.7 1.0 -0.6 0.3 0.4 -0.1 0.3 0.5 0.6 -0.6 0.6 -0.6 -0.3 0.3 0.3 -0.1 0.8 0.8 0.7 0.1 0.8 0.7 -0.3 -1.1 -0.4 -0.7 0.8 0.2 0.4 0.7 -0.4 0.8 0.4 0.5 0.7 0.8 -0.4 0.2 0.7 0.8
Wheeze or whistling in the chest in last year 0.8 1.4 3.3 0.1 1.1 1.5 1.4 1.0 0.5 0.9 -0.1 -0.1 1.2 1.2 0.0 1.5 0.8 -1.6 1.2 1.6 0.1 1.6 1.6 1.7 0.6 1.8 1.5 0.8 0.4 1.2 0.5 1.6 1.7 1.2 1.0 0.1 1.1 1.4 1.1 1.0 1.7 1.2 1.1 1.3 1.6
Number of children fathered 0.3 0.3 4.0 0.7 0.4 1.3 0.6 2.0 -0.4 0.2 0.3 -1.4 -0.3 0.4 0.1 -0.0 0.5 -0.5 -0.2 0.4 -0.2 0.3 0.3 -0.1 -0.7 -0.1 0.0 0.3 0.2 1.2 0.8 0.3 0.4 -0.0 0.3 -0.1 0.1 -0.1 0.6 -0.6 0.3 0.1 0.5 0.1 0.3
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 6.3 1.7 0.8 0.6 0.8 2.0 -0.2 0.3 2.5 0.3 -0.6 0.3 0.8 -0.2 1.1 -0.2 -0.5 0.4 0.1 -0.1 -0.0 -0.1 -1.1 -1.0 -0.2 1.3 2.4 1.8 1.8 -0.1 0.2 -0.6 0.4 1.0 -0.0 0.1 0.1 -0.5 -0.0 1.5 0.7 -0.2 -0.1
Age at first live birth 0.2 0.3 1.7 -0.6 0.0 -0.3 -0.9 -0.6 0.8 0.5 0.6 -0.1 0.2 -0.2 0.9 -0.0 0.8 1.1 0.4 -0.1 0.9 -0.2 -0.2 -0.9 -0.8 -0.3 -0.0 0.6 0.3 0.1 -0.8 -0.2 -0.1 0.8 -0.2 1.3 0.0 0.2 -0.1 1.2 -0.3 0.2 -0.5 0.2 -0.2
Pulse wave peak to peak time 0.7 0.9 3.7 -0.8 0.9 1.6 -0.2 0.7 1.1 0.8 0.8 -0.9 1.3 1.0 1.1 1.0 1.0 -0.6 1.2 0.7 0.9 0.8 0.8 0.7 1.9 0.8 0.9 1.0 0.0 0.5 -1.0 0.8 0.6 1.1 1.1 0.7 1.0 1.0 1.0 1.0 0.7 0.4 0.1 1.0 0.8
Health satisfaction 0.4 0.6 4.0 -1.1 -1.0 -0.7 0.1 0.4 -0.1 -0.7 -1.0 -0.3 0.3 -0.6 -0.5 -0.3 -0.7 0.6 0.1 -1.0 -0.4 -0.5 -0.4 -0.6 1.0 1.1 -0.2 -0.6 -2.0 0.4 -1.1 -0.5 -1.0 -0.4 -0.4 -1.3 -0.5 -0.8 -0.8 -0.6 -0.4 -1.7 0.3 -0.3 -0.5
Shortness of breath walking on level ground 0.2 0.2 1.6 -1.0 -0.3 0.9 -0.2 -0.1 0.7 0.2 -0.3 -1.0 0.4 -0.2 -0.2 0.2 -0.3 0.8 0.1 -0.4 0.1 -0.2 -0.2 -0.5 0.6 0.6 0.2 0.1 -0.8 1.0 -1.3 -0.2 -0.5 -0.1 0.1 0.2 -0.0 0.1 -0.0 0.4 -0.1 -0.4 -0.0 -0.1 -0.2
Qualifications: College or University degree 0.5 1.5 8.8 1.0 1.3 1.3 0.6 1.8 0.5 1.0 3.0 -0.1 0.6 1.3 2.2 0.4 1.6 0.9 0.8 0.5 1.6 0.7 0.6 0.7 -0.0 0.5 0.4 1.6 2.0 1.7 1.0 0.7 -0.0 1.2 1.1 2.6 1.6 0.6 1.3 0.9 0.5 0.8 1.4 0.9 0.7
Eye problems/disorders: None of the above 0.9 1.1 2.7 -1.2 -1.5 -0.4 -1.6 0.3 0.1 -0.5 -1.5 -0.7 -0.4 -1.4 -0.3 -1.0 -0.6 0.8 -0.2 -1.6 0.1 -1.2 -1.2 -1.5 -0.8 0.1 -1.0 -0.4 -1.4 0.9 -1.4 -1.2 -1.4 -0.6 -1.1 -0.5 -1.6 -0.7 -1.1 -0.9 -1.3 -1.3 -0.4 -0.9 -1.2
Mouth/teeth dental problems: Loose teeth 0.5 0.6 3.1 -0.2 -0.9 -0.8 -0.3 -1.3 -0.3 -0.5 -1.8 1.1 -0.5 -0.9 -1.1 -0.5 -0.9 0.8 -0.6 -0.8 -0.7 -0.6 -0.6 -0.9 -1.2 0.7 -0.5 -0.8 -0.8 -0.8 -0.2 -0.6 -0.7 -0.5 -0.3 -0.8 -0.7 -0.6 -0.5 -0.4 -0.6 -0.2 -1.2 -0.6 -0.6
Emphysema/chronic bronchitis 0.2 0.2 1.0 -0.1 -0.3 0.8 0.2 0.8 -0.2 -0.1 -0.2 0.7 0.0 -0.1 -0.3 -0.2 0.8 -0.3 0.2 0.1 -0.5 0.0 0.0 -0.1 0.4 0.4 -0.1 -0.0 -1.0 0.6 -0.2 0.0 0.3 0.2 -0.8 -0.5 -0.4 -0.0 -0.6 -0.3 0.0 -0.7 0.8 -0.1 0.0
Medication for pain relief, constipation, heartburn 0.3 0.4 3.6 0.6 -0.5 0.4 -0.2 0.4 -0.9 -1.0 0.8 -0.0 -0.9 -0.5 -0.1 -0.9 -0.3 1.1 -0.7 -0.7 -0.4 -0.7 -0.7 -0.7 0.1 -1.9 -0.8 -0.4 0.2 -0.1 0.7 -0.7 -0.8 -0.4 -0.3 0.8 -0.4 -0.6 -0.4 -0.2 -0.8 -0.3 -0.0 -0.7 -0.7
Neck or shoulder pain in last month 0.2 0.3 1.3 1.1 0.2 -1.1 -0.1 -0.1 -0.7 -0.3 0.2 0.8 -0.8 -0.0 -0.9 -0.3 -0.7 -0.1 -0.6 0.2 -0.9 -0.1 -0.1 0.1 -0.5 -0.6 -0.4 -0.4 0.7 -0.3 1.0 -0.1 0.3 -0.1 -0.7 0.2 -0.4 -0.1 -0.2 -0.6 -0.1 0.8 -0.3 -0.4 -0.1
Medication: Blood pressure 2.3 4.0 12.2 -0.9 -2.4 -2.3 -1.8 -1.2 -1.0 -1.5 -2.9 0.9 -1.2 -2.1 -2.7 -1.7 -2.2 0.8 -1.7 -2.5 -1.9 -1.7 -1.7 -2.2 -1.6 -1.5 -1.6 -2.3 -3.5 -2.0 -1.1 -1.7 -2.6 -2.2 -2.0 -3.4 -1.8 -1.8 -2.2 -2.1 -1.6 -3.0 -1.1 -1.7 -1.7
Angina (self-reported) 0.2 0.3 2.0 -1.4 -0.0 -0.5 -0.4 -0.0 1.3 0.8 -0.6 -0.5 0.9 0.1 0.0 0.4 0.4 0.3 0.5 -0.2 0.4 0.1 0.1 0.4 0.8 0.0 0.5 0.8 -1.1 -0.1 -1.4 0.1 -0.2 -0.2 0.4 -1.0 0.2 0.2 -0.0 -0.3 0.2 -0.2 -0.1 0.3 0.1
Migraine (self-reported) 0.3 0.4 3.8 -1.2 0.0 -0.8 -0.8 -1.2 0.8 0.4 -1.5 1.9 0.3 0.1 -0.1 0.3 0.1 0.4 0.1 0.1 0.3 0.1 0.1 0.4 0.8 -0.9 0.4 -0.2 -0.5 0.4 -1.3 0.1 0.2 -0.1 0.7 -0.5 0.4 0.6 0.6 -0.6 0.2 -0.2 0.2 0.3 0.1
Medication: Ibuprofen 0.3 0.4 1.3 -0.1 0.7 -0.0 0.1 -0.1 0.5 0.6 -0.2 0.2 0.8 0.5 0.1 1.0 -0.2 -0.9 0.8 0.8 0.4 0.7 0.8 0.8 -0.0 1.0 0.8 0.3 -0.0 -0.1 -0.4 0.7 1.0 1.0 0.3 0.3 0.5 0.6 0.7 1.1 0.8 0.7 -0.7 0.7 0.7
Medication: Allopurinol 0.4 0.5 2.6 -1.2 0.4 1.2 0.7 0.4 1.1 0.8 0.6 1.0 1.0 0.4 0.8 0.7 0.7 0.1 0.6 0.2 0.8 0.3 0.4 0.2 0.3 0.7 0.9 1.0 0.1 1.6 -0.9 0.3 -0.0 0.3 1.0 0.9 0.7 0.9 0.7 -0.0 0.6 0.2 1.1 0.6 0.3
Medication: Omeprazole 1.4 1.6 6.5 0.5 1.5 0.2 1.6 0.3 0.4 1.4 1.4 0.2 1.2 1.6 0.6 1.6 0.9 -2.5 1.6 1.3 1.0 1.7 1.7 1.5 -0.4 1.8 1.5 0.7 1.1 0.4 1.2 1.7 1.2 1.3 0.1 0.0 0.8 0.9 1.0 0.7 1.8 1.1 2.1 1.5 1.7
Medication: Seretide 50 evohaler 0.5 0.6 6.3 0.2 0.6 -0.6 0.8 -0.3 0.2 0.8 -0.2 2.5 0.6 0.6 0.2 0.9 0.2 -0.3 0.5 0.9 0.5 0.9 1.0 1.1 0.0 0.9 0.9 0.3 0.2 0.3 0.7 0.9 1.0 0.6 0.7 0.1 0.8 0.5 0.8 0.2 1.0 0.3 0.5 0.8 0.9
Mean time to correctly identify matches 0.2 0.3 1.8 -1.2 0.1 -1.4 -0.1 -1.3 1.0 0.4 -0.6 0.2 0.6 0.1 -0.3 0.5 -0.1 -0.1 0.4 -0.1 0.1 0.3 0.3 0.1 0.7 0.2 0.6 0.2 -0.8 -0.9 -1.2 0.3 -0.1 -0.2 0.8 -1.0 -0.1 0.3 0.1 0.1 0.4 -0.1 -0.3 0.4 0.3
Heart disease (mother) 3.4 4.1 9.7 2.7 -1.6 -0.0 -0.6 -0.4 -3.1 -2.6 0.5 0.4 -2.9 -1.7 -2.6 -2.3 -2.3 1.7 -2.7 -2.0 -2.9 -1.9 -1.9 -1.7 -2.9 -0.9 -2.3 -2.4 -0.4 -1.5 2.1 -1.9 -2.2 -2.2 -2.4 -1.1 -2.3 -2.6 -2.4 -1.1 -1.8 -1.3 -0.9 -2.5 -1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.4 5.0 -0.5 -0.1 0.6 -0.0 -0.3 0.6 0.1 -1.2 -2.2 1.0 -0.1 0.2 0.7 -0.2 0.3 0.7 0.2 0.3 0.2 0.3 0.2 0.9 0.4 0.6 0.2 -0.5 0.5 -0.9 0.2 0.5 0.6 0.4 0.6 0.6 0.5 0.3 0.7 0.4 0.2 -0.7 0.4 0.2
Whole body fat mass 1.4 5.7 24.8 -1.2 -2.6 -3.0 -1.3 -1.8 -1.5 -2.5 -2.5 -0.5 -1.4 -2.2 -3.0 -1.9 -3.8 0.8 -1.9 -2.4 -2.5 -1.8 -1.8 -2.1 -1.3 -0.3 -1.7 -3.6 -3.8 -3.8 -1.7 -1.8 -2.4 -2.7 -2.1 -5.0 -2.2 -2.6 -2.8 -2.0 -1.8 -3.5 -1.6 -1.8 -1.8
Leg fat mass (right) 1.4 5.6 21.9 -0.7 -2.5 -2.9 -1.3 -1.2 -1.8 -2.7 -2.3 -0.7 -1.7 -2.2 -3.0 -1.9 -3.8 0.6 -2.2 -2.3 -2.7 -1.9 -1.9 -2.1 -1.7 -0.5 -1.8 -3.6 -3.3 -3.4 -1.2 -1.9 -2.3 -2.8 -2.0 -4.7 -2.2 -2.6 -2.7 -1.9 -1.8 -3.2 -2.1 -2.0 -1.9
Arm predicted mass (right) 0.1 0.6 4.6 0.3 -0.5 -0.5 0.2 0.7 -1.2 -1.3 -0.2 -2.2 -0.7 -0.5 -1.0 -0.5 -1.4 -0.1 -0.8 -0.7 -1.1 -0.4 -0.4 -0.7 -1.0 0.4 -0.5 -1.7 -0.6 -0.8 0.2 -0.4 -0.7 -0.5 -0.4 -1.0 -0.4 -0.9 -0.5 0.0 -0.3 -1.1 -0.8 -0.6 -0.4
Pulse rate, automated reading 0.1 0.3 2.9 -0.1 -0.2 -0.2 -0.1 -1.2 -0.1 0.0 -0.4 1.7 -0.2 -0.3 -0.2 -0.2 -1.2 0.4 -0.6 -0.2 -0.3 -0.3 -0.3 -0.2 -1.1 -0.1 -0.2 -0.0 -0.2 -1.0 -0.2 -0.3 -0.3 -0.8 0.3 -0.7 -0.2 -0.3 -0.1 -0.9 -0.2 -0.1 -0.6 -0.3 -0.3
Alcohol intake frequency. 0.6 1.4 7.2 -1.5 0.9 -1.6 0.6 -0.8 1.3 1.1 -1.0 -1.2 1.1 1.0 0.2 1.4 0.2 -1.1 0.9 1.2 0.8 1.1 1.1 1.3 2.7 2.0 1.4 0.3 -0.1 -1.2 -1.2 1.1 1.4 0.5 1.6 -0.7 0.6 1.1 0.8 1.6 1.2 0.8 -0.4 1.1 1.1
Comparative height size at age 10 0.0 0.3 3.4 0.5 0.2 1.0 0.5 1.1 -0.2 0.1 0.5 -1.8 0.1 0.3 0.2 0.0 0.3 0.6 -0.2 0.1 0.1 0.3 0.3 -0.0 -0.9 -0.0 0.2 0.2 0.0 -0.1 0.7 0.3 -0.1 0.1 0.2 0.2 0.6 -0.0 0.1 -0.1 0.3 -0.5 1.0 0.2 0.3
Number of full sisters 1.6 2.0 4.4 -1.4 1.1 1.5 0.5 -1.2 1.6 1.4 -0.3 0.8 2.1 1.2 0.9 1.8 1.6 -1.4 2.0 1.2 1.4 1.6 1.6 0.9 1.4 2.0 1.8 1.3 0.0 0.2 -1.0 1.6 1.4 1.9 1.5 1.2 1.4 1.8 1.4 2.0 1.6 1.0 0.8 1.7 1.6
Suffer from ‘nerves’ 0.6 0.9 3.3 -1.1 0.6 0.3 0.3 -1.6 1.2 0.8 -0.8 1.8 1.2 0.6 0.3 1.1 -0.0 0.2 1.1 0.6 0.8 0.8 0.9 1.0 1.2 1.2 1.1 0.8 -0.0 -0.5 -1.3 0.8 0.7 1.3 1.0 0.9 0.9 1.2 0.8 1.8 0.9 0.9 -0.8 1.0 0.8
Overall health rating 0.8 1.7 7.1 -0.6 -1.1 -2.5 -0.2 -1.8 -0.3 -0.9 -2.4 2.2 -0.6 -1.0 -2.2 -0.5 -2.4 0.3 -0.9 -0.8 -1.7 -0.8 -0.7 0.1 0.4 0.8 -0.5 -1.4 -1.5 -1.9 -0.8 -0.8 -0.6 -1.3 -0.8 -2.7 -1.2 -0.9 -1.2 -0.7 -0.6 -0.4 -2.1 -1.0 -0.8
Chest pain or discomfort 0.1 0.2 1.5 0.7 0.1 0.7 -0.0 -0.1 -0.2 0.1 -0.1 1.1 -0.4 -0.1 -0.6 -0.1 0.2 0.4 -0.2 0.2 -0.4 -0.1 -0.1 0.5 -0.3 0.7 -0.2 0.3 0.9 -0.2 1.0 -0.1 0.2 0.1 -0.8 0.1 -0.4 -0.2 -0.3 0.3 -0.1 1.2 -0.5 -0.4 -0.1
Had major operations 1.7 2.0 4.1 0.3 1.8 -0.4 1.4 0.8 0.7 1.6 1.4 0.1 1.3 2.0 0.9 1.7 1.2 -1.5 1.2 1.6 0.9 1.8 1.8 1.7 1.1 1.5 1.6 1.1 0.9 0.9 0.5 1.8 1.4 1.8 1.6 1.0 1.9 1.2 1.7 1.7 1.8 1.1 0.8 1.6 1.8
Age at last live birth 0.3 0.5 3.4 1.5 0.6 -1.1 0.2 -0.3 -0.8 0.1 1.0 0.2 -0.6 0.4 -0.4 0.1 0.2 -0.3 -0.4 0.5 -0.3 0.5 0.5 -0.2 -1.5 0.2 0.1 -0.3 1.0 -0.4 1.5 0.5 0.6 0.7 -0.1 1.0 0.4 -0.3 0.0 1.8 0.4 0.8 -0.6 0.2 0.5
Family relationship satisfaction 0.5 0.6 2.0 -0.7 0.2 -0.8 1.0 0.0 0.2 -0.2 -1.3 0.5 0.8 0.5 -0.9 0.8 -0.4 -0.7 0.5 0.5 -0.6 0.9 0.9 0.9 1.4 0.8 1.0 -0.8 -1.1 -1.0 -0.8 0.9 0.8 0.4 1.0 -1.2 0.7 0.5 0.7 0.5 1.0 -0.3 -0.4 0.7 0.9
Leg pain on walking 1.0 1.3 3.5 -0.9 1.2 -0.1 1.2 -0.0 1.3 1.5 0.3 -0.9 1.5 1.3 0.9 1.5 0.6 -1.4 1.4 0.9 1.3 1.3 1.4 1.4 1.4 1.3 1.6 1.3 0.4 0.4 -0.5 1.3 0.8 0.8 1.2 0.2 1.1 1.1 1.1 0.4 1.5 0.7 1.9 1.4 1.3
Qualifications: NVQ or HND or HNC or equivalent 2.0 2.4 4.3 -0.8 -1.9 -0.8 -1.9 -0.5 -0.5 -1.6 -1.8 -1.1 -0.9 -1.9 -1.4 -1.5 -2.0 1.4 -1.3 -1.9 -1.3 -1.8 -1.8 -1.8 -0.9 -1.2 -1.5 -1.2 -1.9 -1.8 -1.4 -1.8 -1.7 -1.7 -1.4 -1.8 -1.6 -1.4 -1.8 -0.8 -1.8 -1.5 -2.1 -1.6 -1.8
Commuting to job workplace: Car/motor vehicle 0.4 0.4 3.2 0.3 -0.2 -0.1 0.3 1.6 -0.9 -0.7 0.7 -1.7 -0.1 0.3 -0.6 -0.1 -0.2 0.5 -0.3 -0.3 -1.1 0.2 0.2 0.2 0.2 -0.2 0.1 -0.9 -1.5 -0.2 0.1 0.2 -0.4 0.3 -0.1 -0.5 0.4 -0.4 0.0 0.2 0.3 -1.8 0.3 -0.1 0.2
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 1.8 0.9 -0.9 -0.8 -0.2 -0.2 -1.2 -1.3 0.3 0.3 -1.1 -0.9 -0.6 -1.2 -1.3 0.8 -1.1 -1.0 -0.8 -1.0 -1.0 -1.1 -0.6 -0.6 -1.1 -1.1 -0.1 -0.9 0.8 -1.0 -1.1 -0.9 -1.1 -0.4 -0.9 -1.3 -1.0 -0.8 -1.0 -1.0 -0.4 -1.1 -1.0
Medication: Aspirin 1.3 1.7 7.8 -1.6 -1.3 -2.1 -0.8 -2.2 0.1 -0.5 -2.4 2.2 -0.2 -1.0 -1.4 -0.7 -1.3 0.5 -0.5 -1.3 -0.8 -0.7 -0.7 -0.2 0.5 0.4 -0.5 -1.3 -2.5 -1.7 -1.8 -0.7 -1.2 -1.2 -0.5 -2.8 -1.0 -0.8 -1.0 -1.3 -0.7 -2.0 -0.8 -0.6 -0.7
Supplements: Vitamin C 0.3 0.4 1.6 -1.0 0.3 -0.7 -0.2 -1.3 0.8 0.6 -0.9 0.8 0.4 0.2 -0.3 0.5 -0.4 -0.4 0.5 0.5 0.2 0.4 0.4 0.7 1.1 0.2 0.5 -0.0 -0.1 -0.1 -1.0 0.4 0.7 0.8 0.1 0.6 0.3 0.8 0.3 1.1 0.3 0.6 -0.2 0.4 0.4
Knee pain experienced in last month 0.7 1.1 5.9 0.4 -0.7 -2.4 -0.3 -0.3 -0.7 -0.7 -0.7 -0.2 -0.9 -0.7 -1.0 -0.8 -1.5 0.6 -0.8 -0.6 -1.0 -0.8 -0.7 -0.5 -0.4 -1.4 -0.7 -1.0 -0.8 -1.4 0.2 -0.8 -0.8 -1.6 -1.6 -2.4 -1.5 -1.0 -1.5 -2.0 -0.7 -0.9 0.6 -0.9 -0.8
Hypertension (Self-reported) 0.3 0.9 4.5 -0.1 -0.8 -1.5 -0.0 -0.7 -1.0 -0.8 -1.7 1.1 -0.3 -0.4 -2.1 -0.2 -0.8 -0.7 -0.6 -0.6 -1.6 -0.1 -0.0 -0.7 -0.1 0.4 -0.2 -1.5 -2.1 -1.5 0.0 -0.1 -0.4 -0.5 -0.6 -2.0 -0.4 -0.8 -0.7 -0.4 0.0 -1.3 -0.9 -0.4 -0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 2.0 -0.6 0.9 0.3 0.3 -0.1 1.2 1.3 0.1 0.9 1.1 0.7 1.3 1.0 1.1 -1.2 1.3 1.1 1.4 0.9 0.9 0.6 0.1 0.1 1.0 1.2 0.9 1.0 -0.3 0.9 1.1 0.4 0.2 -0.2 0.5 1.0 0.7 -0.6 0.8 1.0 1.4 1.1 0.9
Illnesses of father: Heart disease 0.2 0.3 1.6 -1.3 0.0 0.4 -0.4 -0.9 0.9 0.5 -0.9 0.7 0.8 0.1 0.5 0.4 0.2 0.1 0.6 0.2 0.7 0.1 0.1 -0.2 0.7 -0.0 0.4 0.5 -0.3 -0.3 -1.0 0.1 0.2 -0.1 0.5 -0.5 0.1 0.5 0.5 -0.6 0.2 0.0 0.5 0.4 0.1
Illnesses of siblings: Diabetes 0.5 0.6 3.5 -1.1 -0.9 -0.6 -0.4 -0.7 -0.1 -0.4 -1.5 -0.3 -0.1 -0.5 -1.0 -0.3 -0.7 0.1 -0.3 -1.1 -0.6 -0.4 -0.3 -0.8 0.2 -0.2 -0.1 -0.8 -1.9 -0.7 -0.9 -0.4 -1.1 -0.6 -0.1 -1.4 -0.7 -0.3 -0.6 -0.6 -0.2 -1.6 0.6 -0.3 -0.4
Smoking status: Previous 0.4 0.5 3.6 1.3 0.4 1.1 1.0 1.9 -1.1 -0.3 1.0 -0.4 -0.5 0.4 -0.7 0.0 0.9 -1.1 -0.5 0.3 -0.8 0.5 0.4 -0.4 -1.1 0.7 0.0 -0.3 0.7 1.4 1.6 0.4 0.3 0.2 -0.1 0.4 0.4 -0.3 0.1 0.0 0.4 0.4 0.7 -0.0 0.5
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 4.2 -0.2 0.6 2.0 0.5 1.6 0.4 0.5 0.2 -1.9 0.5 0.7 1.0 0.5 1.0 0.6 0.4 0.5 0.8 0.5 0.5 0.2 -0.1 0.3 0.5 0.7 0.6 1.9 -0.1 0.5 0.4 0.7 1.3 1.9 1.3 0.9 1.2 0.8 0.5 0.4 0.4 0.6 0.5
Whole body fat-free mass 0.3 1.9 6.4 0.3 -1.3 -1.2 -0.5 0.4 -1.6 -2.0 -0.9 -2.5 -1.3 -1.2 -1.8 -1.3 -2.0 0.5 -1.5 -1.4 -1.8 -1.1 -1.1 -1.4 -1.0 -0.1 -1.3 -2.4 -1.4 -1.6 -0.0 -1.1 -1.4 -1.2 -1.0 -1.7 -1.1 -1.6 -1.4 -0.2 -1.1 -1.8 -1.6 -1.3 -1.1
Leg fat-free mass (right) 0.5 2.8 8.0 -0.2 -1.7 -2.0 -0.7 -0.4 -1.6 -2.2 -1.7 -2.1 -1.4 -1.5 -2.3 -1.5 -2.6 0.7 -1.6 -1.7 -2.0 -1.3 -1.3 -1.5 -0.8 -0.2 -1.5 -2.8 -2.2 -2.6 -0.6 -1.3 -1.7 -1.6 -1.2 -2.6 -1.3 -2.0 -1.7 -0.5 -1.4 -2.3 -1.9 -1.4 -1.3
Arm fat percentage (left) 1.7 6.9 28.4 -1.0 -2.8 -3.4 -1.4 -2.0 -1.8 -2.8 -2.7 -0.0 -1.8 -2.4 -3.3 -2.2 -4.1 0.9 -2.2 -2.5 -2.8 -2.1 -2.1 -2.2 -1.2 -0.6 -2.1 -3.8 -3.9 -4.3 -1.6 -2.1 -2.4 -3.0 -2.4 -5.3 -2.4 -3.0 -3.1 -2.2 -2.2 -3.5 -2.1 -2.1 -2.1
Average weekly red wine intake 0.8 1.2 4.9 -0.2 -1.1 -0.6 -1.1 -0.6 -0.5 -1.4 -0.5 -0.0 -1.0 -1.3 -0.6 -1.1 -0.7 1.7 -1.2 -1.2 -0.9 -1.4 -1.4 -1.9 -1.2 -0.7 -1.1 -1.2 -0.1 -1.0 -0.8 -1.4 -1.3 -0.8 -0.6 -0.0 -0.9 -0.8 -0.8 -0.2 -1.3 -0.6 -2.2 -1.2 -1.4
Handedness (chirality/laterality): Left-handed 1.2 1.4 3.2 0.5 1.3 0.8 1.0 0.3 0.1 0.8 0.7 1.6 0.9 1.3 0.5 1.3 1.3 -1.5 0.9 1.5 0.2 1.5 1.5 1.2 0.2 1.2 1.1 0.9 0.9 0.9 0.7 1.5 1.6 1.7 1.4 1.3 1.4 1.1 1.7 1.8 1.4 1.3 0.3 1.2 1.5
Mood swings 1.6 2.8 8.5 -1.9 -2.0 -2.0 -1.9 -1.0 -0.0 -1.7 -2.8 -0.1 -0.3 -1.9 -2.0 -0.9 -2.2 1.7 -1.0 -2.1 -1.4 -1.5 -1.4 -1.6 -0.1 -0.2 -0.8 -1.9 -2.9 -1.2 -2.5 -1.5 -2.0 -1.6 -0.7 -2.7 -1.5 -1.1 -1.7 -0.9 -1.3 -2.1 -2.5 -1.2 -1.5
Loneliness, isolation 1.1 1.5 6.0 -1.9 -1.4 -1.5 -1.0 -1.2 0.1 -1.0 -2.3 -0.3 0.2 -1.1 -1.4 -0.4 -1.5 0.7 -0.1 -1.4 -0.6 -0.6 -0.6 -0.8 0.2 0.2 -0.3 -1.8 -2.4 -2.4 -2.2 -0.6 -1.1 -0.9 0.0 -2.5 -0.6 -0.8 -0.7 -0.0 -0.6 -1.6 -1.6 -0.3 -0.6
Long-standing illness, disability or infirmity 0.2 0.2 2.0 -0.5 -0.1 -1.0 0.0 -1.3 0.4 0.2 -0.5 0.2 0.0 -0.2 -0.6 0.2 -0.8 0.0 -0.1 0.1 -0.1 -0.1 -0.0 0.5 0.9 0.7 0.1 -0.0 0.3 -1.4 -0.5 -0.1 0.3 -0.3 -0.4 -0.3 -0.1 0.2 -0.5 0.2 -0.0 0.9 -0.4 -0.1 -0.1
Ever had bowel cancer screening 0.2 0.2 1.4 1.2 0.4 -0.5 0.4 -0.2 -0.4 0.3 0.7 0.2 -0.5 0.1 -0.1 -0.2 0.1 -0.4 -0.3 0.4 0.0 0.1 0.0 -0.3 -1.2 0.2 -0.3 0.1 1.1 0.9 1.1 0.1 0.4 0.0 -0.5 0.5 -0.1 -0.1 0.1 0.2 -0.1 1.0 -0.1 -0.1 0.1
Diabetes diagnosed by doctor 0.7 1.2 3.2 -0.9 -1.4 -1.7 -1.4 -0.7 -0.2 -1.0 -1.4 -0.5 -0.4 -1.2 -1.0 -0.9 -1.3 0.8 -0.8 -1.5 -0.7 -1.2 -1.1 -0.9 0.4 -0.3 -0.9 -1.2 -1.8 -1.0 -1.2 -1.2 -1.5 -1.3 -0.7 -1.6 -0.9 -0.9 -1.1 -0.8 -1.1 -1.7 -0.9 -0.9 -1.2
Ever had stillbirth, spontaneous miscarriage or termination 1.9 2.0 6.1 0.9 -1.2 -0.1 -0.6 0.9 -1.7 -1.3 0.4 0.3 -1.6 -0.9 -1.1 -1.8 -1.1 1.2 -1.6 -1.7 -1.5 -1.4 -1.4 -1.3 -1.2 -2.5 -1.6 -1.2 -1.2 0.1 0.9 -1.4 -2.0 -1.6 -1.8 -1.4 -1.6 -1.9 -1.7 -2.0 -1.4 -2.2 0.6 -1.6 -1.4
Friendships satisfaction 1.7 2.1 6.4 0.9 -1.6 -1.6 -0.8 1.0 -2.2 -2.5 -1.7 -0.8 -1.3 -1.3 -2.3 -1.3 -0.8 0.6 -1.5 -1.4 -2.4 -1.0 -1.0 -1.3 -1.1 -0.8 -1.2 -2.5 -2.1 -0.7 0.4 -1.0 -1.1 -1.2 -0.9 -2.0 -1.1 -1.6 -1.4 -0.4 -0.9 -2.1 -1.6 -1.4 -1.0
Qualifications: nursing, teaching 0.5 0.8 5.2 0.6 0.7 2.1 0.3 2.1 0.1 0.4 2.3 -0.5 0.2 0.6 1.0 0.1 1.8 0.0 0.4 0.4 0.6 0.5 0.4 -0.1 -0.9 0.5 0.2 0.9 0.9 2.2 0.4 0.4 -0.0 0.5 0.4 1.2 0.3 0.4 0.5 0.7 0.3 0.3 1.3 0.5 0.5
Commuting to job workplace: Walk 0.3 0.3 1.8 -0.8 0.1 -0.3 -0.1 -0.5 0.9 0.5 -0.6 0.5 0.6 0.0 0.2 0.6 0.8 -0.3 0.6 0.1 0.8 0.3 0.3 0.1 0.3 -0.5 0.6 0.3 0.3 1.4 -0.5 0.3 0.4 0.5 0.4 1.0 0.3 1.0 0.3 0.8 0.4 0.6 0.7 0.5 0.3
Eye problems/disorders: Cataract 0.5 0.5 4.6 2.0 0.7 0.8 0.8 0.9 -1.2 -0.4 1.5 0.8 -0.6 0.6 -0.3 0.0 -0.2 -0.4 -0.6 0.5 -0.9 0.4 0.4 0.4 -0.1 -0.9 0.0 -0.4 0.7 -0.0 2.1 0.4 0.3 0.0 0.3 0.2 0.8 -0.5 0.4 0.3 0.4 0.2 0.1 -0.0 0.4
Mouth/teeth dental problems: Mouth ulcers 0.8 1.2 8.7 1.1 1.0 0.2 1.2 2.9 -0.9 0.2 1.6 -1.1 0.1 1.4 -0.6 0.9 0.8 -1.4 -0.1 1.1 -0.8 1.4 1.4 1.5 0.3 0.9 0.9 -0.3 -0.1 1.7 1.5 1.4 1.1 1.1 0.7 0.5 1.5 0.1 0.9 1.4 1.4 0.1 0.7 0.7 1.4
Medication for cholesterol 0.5 0.7 3.5 0.4 0.8 1.2 0.5 -0.4 0.6 1.0 1.0 0.6 0.1 0.4 0.9 0.4 1.4 -0.2 0.4 0.9 1.0 0.4 0.4 -0.1 -0.7 -1.1 0.4 1.2 1.8 0.9 0.8 0.4 0.9 0.5 -0.0 1.9 0.3 0.9 0.5 0.2 0.4 1.6 1.1 0.4 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.0 5.8 -0.5 -0.8 -2.3 -1.0 -2.4 0.4 -0.3 -1.0 0.6 -0.3 -1.1 -0.6 -0.4 -2.1 0.7 -0.3 -0.8 0.0 -1.0 -0.9 -0.3 -0.3 -0.2 -0.5 -0.5 -0.3 -0.7 -0.7 -1.0 -0.8 -1.4 -1.4 -1.5 -1.2 -0.9 -1.4 -1.7 -0.8 -0.2 -0.6 -0.8 -1.0
Back pain experienced in last month 0.3 0.4 2.6 -0.4 0.1 -0.8 0.2 -1.2 0.3 0.5 -1.6 -0.3 0.5 0.2 -0.6 0.9 -0.1 -0.3 0.6 0.4 0.1 0.7 0.7 0.1 -0.3 0.6 0.8 -0.3 -0.5 -0.3 -0.0 0.7 0.7 1.2 -0.5 0.6 0.3 1.0 0.2 1.4 0.8 0.4 0.3 0.5 0.7
Mineral and other dietary supplements 2.8 3.7 7.1 1.0 -2.2 -0.5 -2.1 1.1 -2.3 -2.3 -1.2 -0.5 -2.5 -2.0 -2.5 -2.4 -1.4 1.2 -2.7 -2.2 -2.6 -2.0 -2.1 -2.4 -1.7 -1.6 -2.4 -2.3 -2.0 0.7 0.5 -2.0 -2.1 -1.7 -1.9 -0.8 -1.7 -2.1 -2.2 -0.9 -2.1 -2.1 -2.1 -2.3 -2.0
Breast cancer (self-reported) 0.1 0.1 0.4 -0.1 -0.1 0.4 -0.0 0.2 -0.0 -0.1 -0.2 -0.5 -0.0 0.0 0.0 -0.1 0.6 0.2 0.0 -0.1 -0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.1 0.1 0.4 -0.1 0.1 -0.1 0.1 0.6 0.1 -0.1 0.4 0.4 -0.4 0.0 -0.3 0.4 0.1 0.1
Asthma (self-reported) 0.1 0.2 1.4 0.5 -0.1 1.0 0.7 1.2 -0.4 -0.0 -0.3 -0.3 0.1 -0.0 0.1 -0.1 0.3 -0.1 0.1 0.1 -0.0 0.0 0.1 0.0 -0.3 -0.2 -0.1 0.3 -0.0 0.7 0.9 0.1 0.2 -0.1 -0.1 -0.2 -0.3 -0.4 0.2 -1.0 0.1 -0.1 0.6 -0.1 0.1
Osteoporosis (self-reported) 0.5 0.6 3.0 -0.3 0.7 -1.7 1.1 -1.2 0.9 0.9 1.0 0.4 0.6 0.5 0.9 0.7 0.9 -0.6 0.8 0.8 1.0 0.6 0.6 0.7 -0.1 0.8 0.7 0.7 1.1 -0.3 -0.1 0.6 0.9 0.5 0.4 0.4 0.4 0.5 0.5 0.5 0.6 1.1 0.6 0.7 0.6
Osteoarthritis (self-reported) 0.8 1.0 2.9 0.3 1.3 -0.9 1.3 -1.4 0.7 1.3 0.6 0.7 0.4 1.1 -0.1 1.2 0.5 -1.6 0.6 1.7 0.2 1.3 1.3 1.2 0.3 1.0 1.1 0.6 0.9 -0.9 0.4 1.3 1.7 0.7 0.4 0.1 0.7 1.0 0.6 0.9 1.3 1.6 0.6 1.0 1.3
Medication: Aspirin 1.3 1.6 7.6 -1.4 -1.3 -1.8 -0.9 -1.9 -0.1 -0.7 -2.1 2.5 -0.2 -1.0 -1.4 -0.7 -1.2 0.5 -0.5 -1.4 -0.8 -0.8 -0.7 -0.4 0.3 0.5 -0.6 -1.3 -2.4 -1.6 -1.5 -0.8 -1.3 -1.1 -0.7 -2.8 -1.0 -1.1 -1.1 -1.4 -0.7 -2.1 -0.6 -0.6 -0.8
Medication: Gliclazide 1.6 1.8 9.2 -2.5 -1.6 -2.0 -1.9 -2.4 0.8 -0.6 -3.0 1.0 0.1 -1.4 -0.8 -0.6 -0.8 0.5 -0.2 -1.1 -0.1 -1.0 -1.0 -1.3 1.0 -0.0 -0.6 -1.1 -2.5 -1.5 -2.7 -1.0 -0.8 -1.1 -0.5 -1.8 -0.6 -0.2 -0.7 -0.5 -1.1 -1.6 -1.3 -0.6 -1.0
Illnesses of father: None of the above (group 1) 0.3 0.4 1.6 0.4 0.6 1.0 0.2 1.0 0.1 0.4 0.9 -1.1 0.2 0.5 0.3 0.6 0.3 -0.5 0.6 0.5 0.4 0.5 0.6 0.8 0.6 0.4 0.5 0.4 0.5 0.7 0.6 0.5 0.6 0.8 -0.2 1.0 0.1 0.6 -0.1 1.2 0.6 0.7 1.1 0.4 0.5
Smoking status: Current 0.4 0.7 5.6 -1.5 -0.1 -0.3 -0.2 -2.3 1.2 0.2 -1.1 2.4 0.9 -0.1 -0.5 0.6 -1.2 -0.3 0.7 -0.1 0.1 0.2 0.2 0.2 1.0 -0.0 0.6 -0.2 -1.0 -0.2 -1.8 0.2 0.1 -0.2 0.1 -1.3 -0.4 0.6 0.1 -0.3 0.2 0.2 -0.3 0.4 0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.4 5.1 1.0 1.8 0.8 1.3 2.0 -0.0 0.9 2.3 -1.1 0.5 1.7 1.4 1.0 1.2 -1.1 0.7 1.7 0.6 1.4 1.3 1.5 0.3 0.8 1.1 0.9 1.4 0.8 1.1 1.4 1.4 1.0 1.2 0.7 1.4 0.5 1.1 0.5 1.3 0.8 1.5 1.1 1.4
Whole body water mass 0.3 1.9 6.2 0.3 -1.3 -1.2 -0.4 0.4 -1.6 -2.0 -0.9 -2.5 -1.4 -1.2 -1.8 -1.3 -2.0 0.5 -1.5 -1.4 -1.8 -1.1 -1.1 -1.4 -1.0 -0.1 -1.3 -2.4 -1.4 -1.6 0.1 -1.1 -1.4 -1.2 -1.0 -1.7 -1.1 -1.7 -1.4 -0.2 -1.1 -1.8 -1.6 -1.3 -1.1
Leg predicted mass (right) 0.5 2.6 7.6 -0.2 -1.6 -2.0 -0.6 -0.5 -1.5 -2.1 -1.6 -2.0 -1.3 -1.4 -2.2 -1.4 -2.5 0.6 -1.6 -1.6 -2.0 -1.2 -1.2 -1.4 -0.7 -0.1 -1.4 -2.8 -2.2 -2.5 -0.6 -1.2 -1.6 -1.5 -1.2 -2.5 -1.2 -1.9 -1.6 -0.4 -1.3 -2.3 -1.8 -1.4 -1.2
Arm fat mass (left) 1.7 7.0 26.0 -0.6 -2.8 -3.4 -1.3 -1.7 -2.1 -3.0 -2.5 -0.7 -2.0 -2.5 -3.3 -2.3 -4.2 1.0 -2.4 -2.6 -2.9 -2.2 -2.2 -2.3 -1.3 -0.5 -2.2 -3.9 -3.4 -4.3 -1.1 -2.2 -2.6 -3.1 -2.4 -5.1 -2.5 -3.2 -3.1 -2.1 -2.2 -3.4 -2.4 -2.3 -2.2
Number of self-reported non-cancer illnesses 1.3 2.3 4.4 -1.6 1.3 -1.2 1.3 -1.8 1.7 1.9 -1.2 1.8 2.0 1.6 0.4 1.9 0.8 -1.3 1.5 1.5 1.1 2.0 2.0 1.9 1.4 2.1 2.0 0.7 -0.7 -1.2 -1.0 2.0 1.6 1.1 1.8 -1.2 2.0 1.4 1.6 0.4 1.9 0.4 0.9 2.0 2.0
Average weekly champagne plus white wine intake 0.9 1.3 7.1 1.9 1.2 1.8 1.0 2.7 -0.7 0.4 2.3 -0.0 -0.3 1.1 1.1 0.3 1.2 0.4 -0.2 1.0 0.3 0.6 0.7 1.2 -0.6 -0.0 0.3 0.8 1.7 1.9 2.3 0.6 0.7 0.4 0.7 1.9 0.9 0.3 1.2 0.4 0.7 0.7 1.4 0.3 0.6
Miserableness 1.8 3.1 6.5 -0.5 -2.2 -2.0 -2.4 -1.1 -1.0 -1.9 -2.6 -0.1 -1.0 -2.2 -2.3 -1.4 -1.4 1.5 -1.3 -2.3 -1.6 -1.8 -1.7 -2.2 -1.2 -1.8 -1.4 -2.0 -2.1 -1.2 -1.2 -1.8 -2.0 -1.8 -1.7 -2.1 -2.1 -1.7 -2.1 -1.2 -1.7 -1.5 -2.3 -1.7 -1.8
Guilty feelings 0.8 1.2 6.8 -1.3 -1.1 -1.7 -0.7 -2.6 0.4 -0.7 -2.5 1.6 -0.1 -1.1 -1.2 -0.4 -0.9 0.9 -0.2 -1.0 -0.5 -0.7 -0.7 -0.9 0.1 -0.7 -0.4 -0.9 -1.7 -1.5 -1.6 -0.7 -0.8 -1.1 -0.5 -1.9 -1.2 -0.1 -0.9 -0.5 -0.7 -0.6 -1.4 -0.5 -0.7
Wears glasses or contact lenses 1.5 1.8 3.7 1.1 -1.5 0.2 -1.2 0.4 -1.9 -1.8 -0.1 0.2 -1.7 -1.4 -1.7 -1.6 -1.2 0.8 -1.7 -1.7 -1.8 -1.4 -1.4 -1.8 -1.8 -1.0 -1.6 -1.4 -0.8 0.6 0.9 -1.4 -1.6 -1.3 -1.6 -0.5 -1.3 -1.6 -1.3 -0.9 -1.4 -1.1 -0.8 -1.6 -1.4
Ever taken oral contraceptive pill 2.3 2.5 4.3 -1.0 1.6 0.4 1.1 0.9 1.8 1.9 0.7 -1.4 2.0 1.5 1.8 2.0 1.2 -1.3 2.0 1.8 1.9 1.6 1.7 1.6 0.9 1.7 1.9 1.7 1.0 1.1 -0.5 1.6 1.9 2.1 1.3 1.8 1.9 2.0 1.6 2.0 1.8 1.5 1.2 1.8 1.7
Hearing aid user 2.8 3.1 5.9 0.4 -2.0 -0.8 -1.8 -0.2 -1.5 -2.1 -1.1 -1.5 -1.9 -2.1 -1.7 -2.2 -1.2 1.2 -1.7 -2.1 -1.8 -2.2 -2.2 -2.2 -1.0 -1.8 -2.2 -1.6 -0.7 -1.1 -0.2 -2.2 -2.2 -1.9 -2.4 -1.5 -2.3 -2.0 -2.4 -2.1 -2.2 -1.2 -1.2 -2.1 -2.1
Mother’s age at death 1.0 1.2 3.1 -0.0 1.0 1.0 0.9 1.6 0.9 1.0 1.1 -1.1 1.2 1.1 1.3 1.0 1.3 -0.7 1.4 1.0 1.1 1.1 1.0 1.3 1.1 1.3 1.0 1.3 0.6 1.8 0.1 1.1 1.1 1.3 1.1 1.1 0.9 1.0 1.2 1.5 1.0 0.9 0.6 1.2 1.1
Financial situation satisfaction 0.7 0.9 4.1 -1.9 -0.0 -0.1 -0.6 -1.7 1.4 0.5 -0.7 1.0 1.7 0.4 0.4 1.1 0.6 -0.7 1.5 0.5 0.8 0.7 0.7 0.1 1.7 0.8 1.0 0.1 -1.5 -0.6 -2.0 0.7 0.8 0.4 0.5 -1.5 0.3 0.2 0.3 0.5 0.7 -0.4 -0.1 0.9 0.6
Tinnitus: Yes, now most or all of the time 1.0 1.2 6.0 -2.0 -1.4 0.5 -2.4 -0.4 0.8 -0.6 -1.1 -1.3 0.3 -1.1 0.2 -0.7 -0.5 1.9 0.0 -1.4 0.3 -1.1 -1.1 -1.3 0.2 -1.6 -0.6 -0.0 -1.7 -0.3 -2.3 -1.1 -1.4 -0.7 -0.6 -0.5 -0.6 -0.4 -1.0 -1.0 -1.1 -1.4 -0.2 -0.5 -1.1
Commuting to job workplace: Public transport 0.4 0.4 2.8 1.7 0.2 0.3 0.4 -0.4 -1.1 -0.4 0.6 0.9 -1.0 -0.0 -0.4 -0.4 -0.8 -0.6 -0.6 0.3 -0.6 -0.1 -0.1 -0.4 -1.1 -0.1 -0.6 -0.5 0.9 -0.9 1.5 -0.1 0.3 -0.6 -0.4 -0.4 -0.6 -0.7 -0.3 -0.2 -0.2 0.7 -0.5 -0.4 -0.1
Eye problems/disorders: Glaucoma 0.1 0.2 1.6 0.2 0.1 -0.0 0.2 -0.6 0.1 -0.0 -0.1 -1.3 -0.1 -0.1 -0.7 0.3 0.2 -0.4 -0.4 0.2 -0.4 0.1 0.1 -0.1 -0.6 -0.5 0.3 -0.1 -0.0 -1.0 0.1 0.1 0.2 -0.3 0.2 -0.2 0.1 0.0 -0.3 0.9 0.2 0.7 -0.8 -0.1 0.1
Medication: Blood pressure 0.5 1.0 4.3 0.2 -0.9 -1.5 -0.1 0.1 -1.3 -1.2 -1.0 -0.2 -0.5 -0.4 -1.4 -0.6 -1.4 0.3 -0.7 -0.8 -1.5 -0.5 -0.4 -0.3 0.9 1.2 -0.6 -1.5 -1.9 -1.4 0.0 -0.5 -0.8 -0.8 -0.7 -2.1 -0.5 -1.4 -0.9 -0.6 -0.4 -1.7 -0.8 -0.7 -0.5
Pain type(s) experienced in last month: Hip pain 0.3 0.3 1.4 -0.7 0.1 -0.5 0.2 -1.1 0.4 0.2 -1.0 0.4 0.7 0.2 -0.7 0.7 0.3 -0.6 0.5 0.4 -0.3 0.6 0.7 0.3 1.2 0.2 0.7 -0.2 -0.8 -0.6 -0.6 0.6 0.7 0.5 -0.2 -0.6 0.2 0.6 -0.3 0.8 0.7 -0.1 0.6 0.5 0.6
Supplements: Fish oil (including cod liver oil) 1.3 1.7 4.6 -1.4 1.1 0.5 1.6 -1.1 1.7 1.2 0.4 0.1 2.0 1.2 1.4 1.9 0.6 -0.9 2.1 1.4 1.5 1.3 1.4 1.4 1.1 1.0 1.8 0.9 0.3 -1.0 -1.1 1.4 1.6 1.5 0.8 0.2 0.7 1.5 1.1 1.1 1.5 0.9 1.4 1.6 1.4
High cholesterol (Self-reported) 0.1 0.3 0.9 0.3 0.6 0.9 -0.1 0.1 0.3 0.7 0.8 0.7 0.3 0.6 0.5 0.6 0.8 -0.2 0.3 0.6 0.3 0.4 0.5 0.8 0.1 0.2 0.6 0.7 0.7 0.1 0.7 0.4 0.5 -0.2 0.1 -0.6 0.0 0.1 0.2 -0.6 0.6 0.4 0.9 0.3 0.4
Medication: Bendroflumethiazide 0.4 0.6 3.1 -0.4 0.3 -0.7 1.1 0.1 -0.0 0.4 -0.1 1.2 0.7 0.8 -0.2 0.7 0.2 -0.7 0.5 0.4 -0.1 0.9 1.0 1.1 0.4 1.2 0.9 -0.1 -1.3 -0.2 0.0 0.9 0.4 0.4 0.6 -0.8 1.0 0.0 0.4 -0.1 1.1 -1.2 1.8 0.8 0.9
Medication: Paracetamol 0.5 0.7 2.9 0.7 -0.6 -1.2 -0.6 0.4 -0.9 -0.6 -0.3 -0.3 -1.0 -0.8 -0.5 -1.1 -0.9 1.1 -1.2 -0.6 -0.8 -1.0 -1.0 -0.4 -1.7 -0.4 -1.2 -0.3 0.1 0.8 0.7 -1.0 -0.7 -1.0 -0.9 -0.5 -0.6 -0.9 -0.9 -1.3 -1.0 -0.4 -0.8 -1.1 -1.0
Medication: Lisinopril 0.2 0.3 2.7 -0.3 0.0 -0.9 0.2 -1.6 0.2 0.2 -1.0 0.6 0.0 -0.0 -0.7 0.3 -0.2 -1.4 0.2 0.0 -0.2 0.1 0.2 -0.3 -0.1 0.4 0.3 -0.4 -0.1 -0.1 -0.2 0.1 0.0 -0.3 -0.2 -1.0 -0.9 0.4 -0.2 0.1 0.3 0.3 0.1 0.0 0.1
Medication: Atorvastatin 0.4 0.4 2.4 -1.4 -0.6 1.6 -0.9 -0.2 0.9 0.0 -0.9 1.5 0.5 -0.4 -0.1 -0.0 0.3 1.0 0.2 -0.5 0.0 -0.3 -0.3 -0.1 1.2 0.2 0.1 0.1 -1.2 0.1 -1.3 -0.3 -0.5 -0.3 0.2 -0.7 -0.0 0.5 -0.2 -0.4 -0.2 -0.7 -0.0 -0.0 -0.3
Illnesses of father: High blood pressure 0.6 0.7 2.7 0.3 1.0 -0.4 1.1 0.3 -0.0 0.8 0.8 1.6 0.6 1.0 0.5 0.8 0.9 -0.9 0.5 1.3 0.3 1.2 1.1 1.0 -0.3 0.7 0.8 0.4 0.2 0.0 0.7 1.2 1.3 0.9 0.8 0.4 1.2 0.4 1.1 0.7 1.1 0.3 0.5 0.9 1.2
Alcohol drinker status: Never 0.6 0.7 3.3 -0.6 -0.9 -0.5 -0.9 -0.4 -0.1 -0.7 -1.4 -0.5 -0.7 -0.9 -0.8 -0.7 -1.0 0.0 -0.7 -0.8 -0.6 -0.9 -0.9 -1.0 0.5 -0.1 -0.7 -0.8 -0.7 -1.4 -0.9 -0.9 -0.7 -1.0 -0.2 -1.0 -1.1 -0.5 -0.7 -0.5 -0.9 -0.4 -1.8 -0.8 -0.9
Ever smoked 1.0 1.7 5.2 0.7 1.4 1.8 1.8 0.8 0.3 1.1 1.5 1.3 1.2 1.5 0.9 1.3 1.1 -1.7 1.4 1.3 0.8 1.6 1.5 0.9 0.7 1.3 1.2 1.1 1.2 2.3 1.1 1.6 1.3 1.3 0.6 1.0 1.1 0.9 1.5 0.5 1.5 1.1 2.3 1.4 1.6
Basal metabolic rate 0.5 2.6 7.5 0.2 -1.6 -1.6 -0.7 0.0 -1.8 -2.2 -1.1 -2.3 -1.5 -1.5 -2.1 -1.6 -2.5 0.7 -1.8 -1.6 -2.0 -1.3 -1.3 -1.6 -1.3 -0.2 -1.5 -2.7 -1.8 -2.1 -0.2 -1.3 -1.7 -1.6 -1.3 -2.2 -1.3 -2.0 -1.7 -0.5 -1.4 -2.1 -1.9 -1.5 -1.3
Leg fat percentage (left) 1.4 4.9 19.3 -0.7 -2.4 -2.6 -1.4 -1.6 -1.6 -2.5 -1.9 0.5 -1.7 -2.1 -2.7 -2.0 -3.6 0.6 -2.0 -2.0 -2.6 -1.9 -1.9 -2.1 -1.5 -0.5 -1.9 -3.1 -3.0 -2.9 -1.3 -1.9 -2.0 -2.7 -2.1 -4.4 -2.4 -2.3 -2.6 -2.1 -1.9 -2.8 -1.8 -2.0 -1.9
Arm fat-free mass (left) 0.4 1.9 5.3 0.5 -1.2 -1.4 -0.6 0.1 -1.6 -1.9 -0.7 -2.2 -1.5 -1.2 -1.8 -1.3 -2.1 0.5 -1.7 -1.3 -1.7 -1.2 -1.1 -1.4 -1.3 -0.2 -1.3 -2.3 -0.9 -1.8 0.1 -1.2 -1.4 -1.4 -1.0 -1.6 -1.1 -1.7 -1.4 -0.4 -1.1 -1.4 -1.8 -1.3 -1.2
Number of operations (self-reported) 1.9 2.9 5.0 -0.5 2.2 -0.3 1.8 -0.2 1.7 2.1 1.4 0.4 2.0 2.1 1.8 2.0 1.9 -1.9 2.1 1.8 1.9 2.1 2.0 2.1 0.1 1.5 2.0 2.0 1.9 1.2 -0.1 2.0 1.4 1.2 1.5 -0.0 1.4 1.9 1.5 0.6 2.0 1.9 2.2 2.1 2.1
Average weekly beer plus cider intake 0.8 1.2 4.2 -0.7 0.9 0.7 1.5 -0.2 0.8 1.1 -0.3 0.6 1.3 1.1 0.6 1.2 1.1 -2.0 1.3 1.1 0.6 1.4 1.4 0.7 0.2 1.4 1.3 0.7 -0.1 1.3 -0.1 1.4 1.2 1.6 1.2 0.8 1.2 1.6 1.4 1.0 1.4 0.4 1.2 1.3 1.4
Irritability 0.6 1.1 6.0 -2.2 0.3 0.3 -0.3 -0.3 1.8 0.7 -1.1 -0.5 1.7 0.4 0.6 1.3 0.3 -0.0 1.5 0.5 1.0 0.7 0.8 0.4 1.6 1.3 1.3 0.5 -0.9 0.7 -2.4 0.7 0.7 1.2 1.2 0.4 0.9 1.5 0.9 1.1 0.8 0.1 -0.6 1.1 0.7
Risk taking 0.4 0.6 4.8 -0.1 -0.8 0.3 -0.0 0.4 -1.0 -1.0 -0.4 1.6 -0.3 -0.2 -0.9 -0.7 -0.4 0.5 -0.5 -0.9 -1.0 -0.2 -0.2 -0.3 -0.3 0.1 -0.5 -1.1 -1.9 0.1 -0.1 -0.2 -1.0 -0.3 -0.1 -1.3 0.0 -0.8 -0.3 -0.7 -0.3 -2.2 0.0 -0.3 -0.2
Ever had prostate specific antigen (PSA) test 0.2 0.2 0.7 -0.2 -0.4 -0.5 -0.3 -0.1 0.4 0.1 -0.8 0.4 -0.3 -0.6 -0.2 -0.4 -0.3 0.4 -0.6 -0.6 0.1 -0.6 -0.6 -0.8 -0.6 0.1 -0.4 0.3 0.2 0.3 -0.5 -0.6 -0.7 -0.6 -0.3 -0.2 -0.4 -0.2 -0.4 -0.4 -0.6 0.2 -0.8 -0.5 -0.6
Fractured/broken bones in last 5 years 0.9 1.1 2.8 -1.0 1.0 -0.1 0.9 -0.4 1.6 1.4 0.3 -0.1 1.5 0.9 1.7 1.2 1.4 -0.8 1.5 1.2 1.7 1.0 1.0 0.9 0.9 0.2 1.2 1.3 0.7 0.2 -0.7 1.0 1.3 1.1 1.1 0.8 1.1 1.3 1.2 0.2 1.0 0.8 0.9 1.3 1.0
Age started oral contraceptive pill 0.9 1.2 3.6 -0.2 -1.1 -0.7 -0.3 -1.3 -0.5 -1.2 -0.1 -1.2 -0.8 -1.3 -1.2 -1.0 -1.6 0.2 -0.7 -1.1 -1.1 -1.3 -1.2 -1.6 -0.9 -0.9 -1.0 -1.2 -0.7 -1.6 -0.8 -1.3 -1.0 -0.9 -1.9 -0.9 -1.6 -0.9 -1.7 -0.8 -1.2 -0.6 -0.7 -1.2 -1.3
Diastolic blood pressure, automated reading 0.1 0.3 2.2 -0.4 -0.3 -0.3 0.2 -1.5 -0.1 -0.2 -1.0 0.9 -0.4 -0.3 -0.7 -0.3 -1.1 -0.2 -0.2 -0.3 -0.4 -0.2 -0.2 -0.7 -0.3 0.6 -0.3 -0.5 -0.3 -1.2 -0.4 -0.2 -0.3 -0.2 -0.2 -0.6 -0.4 -0.1 -0.2 -0.7 -0.3 0.0 -0.3 -0.2 -0.2
Ever depressed for a whole week 0.2 0.3 2.3 -1.0 -0.5 -0.9 -0.7 -0.4 0.4 0.1 -1.5 0.1 -0.1 -0.6 -0.2 -0.3 -0.1 0.9 -0.2 -0.5 0.0 -0.6 -0.6 -0.4 0.1 -0.1 -0.3 0.1 -0.4 0.6 -1.1 -0.6 -0.4 -0.5 -0.2 -0.4 -0.5 0.0 -0.5 -0.2 -0.5 -0.0 -0.9 -0.4 -0.6
Unable to work because of sickness or disability 1.9 2.5 5.2 -0.7 1.9 0.6 1.4 -0.3 1.6 2.0 1.3 1.4 1.7 1.9 1.3 1.9 1.4 -1.9 1.7 1.8 1.5 1.9 1.9 1.7 1.3 2.3 1.9 1.8 1.2 0.5 -0.4 1.9 1.7 1.4 1.9 0.6 1.5 1.7 1.7 1.4 1.9 1.8 1.0 1.9 1.9
Commuting to job workplace: Cycle 0.4 0.5 2.9 -0.6 0.5 0.1 -0.6 -0.9 1.3 0.9 0.1 -0.3 0.5 0.1 1.4 0.4 0.6 0.5 0.7 0.3 1.4 -0.1 -0.1 0.0 -0.2 0.1 0.2 1.4 1.7 0.5 -0.9 -0.1 0.2 0.2 0.3 0.9 0.1 0.7 0.2 0.1 -0.1 1.7 -0.5 0.3 -0.1
Myopia 0.3 0.4 3.0 -1.0 -0.3 -1.0 -0.5 -0.2 0.3 0.1 -1.0 -1.7 0.3 0.0 -0.6 0.1 -0.4 0.0 0.3 -0.4 0.1 0.3 0.2 -0.1 0.8 1.0 0.2 -0.6 -1.5 -0.1 -1.3 0.3 -0.2 0.8 0.0 -0.1 0.6 0.3 -0.0 1.2 0.1 -0.9 -0.4 0.4 0.3
Vascular/heart problems diagnosed by doctor 0.4 1.1 8.2 0.9 1.1 1.8 0.5 0.8 0.6 0.8 2.2 -1.5 -0.0 0.6 1.9 0.2 0.7 0.3 0.4 1.0 1.4 0.2 0.2 0.7 -0.3 -0.2 0.2 1.4 2.9 1.1 0.8 0.2 0.8 0.7 0.6 2.4 0.4 0.7 0.8 0.7 0.1 1.9 0.7 0.4 0.2
Cholesterol lowering medication 0.2 0.2 2.7 0.7 0.4 0.0 0.6 0.4 -0.5 -0.2 0.8 0.4 0.0 0.4 -0.0 0.3 -0.6 0.1 -0.1 0.3 -0.4 0.2 0.3 1.1 0.4 1.6 0.2 -0.1 0.4 -0.7 0.6 0.2 0.2 -0.0 0.4 -0.4 0.2 -0.5 0.4 0.2 0.4 0.1 -0.4 0.0 0.2
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 2.6 1.1 0.7 -0.4 0.9 0.3 -0.6 0.4 1.1 0.5 0.3 0.7 -0.2 0.7 0.2 -1.4 0.5 0.4 0.0 0.8 0.8 0.5 -1.3 1.5 0.6 -0.2 0.8 0.1 1.6 0.8 0.2 0.6 -0.6 -0.2 0.1 -0.1 0.3 0.2 0.9 0.5 1.0 0.5 0.8
Pain experienced in last month 0.6 1.0 4.4 0.4 -1.0 0.0 -0.8 0.9 -1.0 -1.4 0.3 -0.3 -1.0 -1.1 -0.6 -1.3 -0.8 0.9 -1.4 -1.3 -0.7 -1.2 -1.3 -1.2 -0.4 -0.4 -1.3 -1.1 -0.2 -0.5 0.1 -1.2 -1.4 -1.2 -0.1 -0.2 -0.3 -1.6 -0.8 -0.0 -1.3 -0.9 -2.1 -1.1 -1.2
Supplements: Calcium 0.5 0.6 1.9 0.3 1.0 0.2 0.7 -0.3 0.4 0.7 0.6 0.6 0.4 0.8 0.5 0.8 0.6 -0.4 0.2 1.1 0.4 0.8 0.8 1.4 0.6 0.6 0.7 0.5 1.1 -0.4 0.4 0.8 1.1 0.6 1.0 0.7 1.3 0.5 1.0 0.9 0.8 1.2 -0.4 0.7 0.8
Basal cell carcinoma (self-reported) 0.1 0.1 0.7 -0.3 -0.1 0.1 -0.4 -0.8 0.4 0.4 -0.0 -0.7 -0.1 -0.1 -0.3 0.0 0.3 0.1 0.2 0.2 0.2 0.1 0.1 -0.6 0.1 -0.6 -0.0 0.0 -0.2 -0.6 -0.4 0.1 0.4 0.2 -0.6 -0.2 -0.5 0.1 -0.2 0.3 -0.1 0.3 0.2 0.1 0.1
Heart attack/myocardial infarction (self-reported) 0.7 1.0 4.9 -2.2 -0.3 -0.1 0.1 -1.0 1.5 0.7 -1.2 0.7 1.6 0.2 0.6 0.6 0.8 -0.0 1.6 -0.2 0.9 0.3 0.3 0.5 2.1 0.7 0.8 0.6 -2.1 -0.7 -2.1 0.3 -0.2 0.6 -0.2 -1.2 -0.3 0.7 -0.2 -0.1 0.4 -1.2 1.2 0.7 0.3
Deep venous thrombosis (DVT) (self-reported) 1.3 1.7 6.6 0.1 -1.1 -0.9 -0.9 -1.2 -0.9 -1.2 -0.9 1.2 -1.1 -1.1 -1.6 -1.0 -1.8 0.9 -1.2 -1.1 -1.5 -1.1 -1.0 -1.1 -0.7 -1.6 -1.0 -1.6 -1.2 -2.3 -0.4 -1.1 -1.1 -1.9 -1.4 -2.6 -1.3 -1.6 -1.4 -2.2 -1.0 -1.0 -1.1 -1.1 -1.1
Heart disease (siblings) 2.7 3.3 9.7 -0.3 -2.1 -1.4 -1.8 -0.5 -1.4 -2.0 -1.7 0.0 -1.5 -1.7 -2.4 -1.8 -2.2 1.2 -1.8 -2.5 -2.1 -1.7 -1.7 -1.4 -0.2 -1.4 -1.6 -2.3 -2.1 -2.2 -0.6 -1.7 -2.6 -2.4 -1.5 -3.1 -1.9 -2.0 -2.1 -2.3 -1.6 -2.2 -0.6 -1.8 -1.7
Alcohol drinker status: Previous 2.7 3.1 6.6 -1.6 1.9 -0.1 1.0 -0.3 2.1 1.9 0.2 -0.4 1.9 1.8 1.2 2.3 1.8 -1.3 1.7 2.0 1.6 1.9 2.0 1.8 2.3 1.9 2.3 1.4 1.1 0.5 -1.1 1.9 2.1 1.6 2.6 1.3 1.9 2.4 2.1 2.6 2.1 1.9 0.4 2.0 1.9
Pack years of smoking 0.5 0.8 4.4 -2.1 -0.5 -0.9 -1.0 -1.0 1.2 0.2 -0.3 1.0 1.2 -0.1 0.9 0.1 0.2 1.1 1.1 -0.7 1.0 -0.2 -0.2 0.1 0.8 -0.8 0.2 0.5 -1.5 -0.1 -2.1 -0.2 -0.7 -0.1 -0.2 -1.2 -0.3 0.1 -0.2 -1.6 -0.2 -1.4 1.3 0.3 -0.2
Impedance of whole body 0.6 3.1 7.8 -1.0 1.3 2.6 0.6 0.6 2.0 2.1 1.4 1.5 2.1 1.6 2.6 1.6 2.6 0.3 2.1 1.2 2.4 1.4 1.4 1.4 1.4 0.9 1.7 2.6 0.9 2.5 -0.5 1.4 1.2 1.9 1.7 2.8 1.9 2.3 1.8 0.9 1.4 0.8 2.7 1.8 1.4
Leg fat mass (left) 1.4 5.5 22.0 -0.7 -2.5 -2.8 -1.3 -1.3 -1.8 -2.7 -2.4 -0.4 -1.7 -2.2 -3.1 -1.9 -3.9 0.6 -2.1 -2.3 -2.8 -1.9 -1.9 -2.1 -1.7 -0.4 -1.8 -3.6 -3.4 -3.2 -1.3 -1.9 -2.3 -2.7 -2.1 -4.7 -2.3 -2.6 -2.7 -1.9 -1.8 -3.2 -2.1 -2.0 -1.9
Arm predicted mass (left) 0.4 2.0 5.2 0.2 -1.4 -1.3 -0.8 -0.0 -1.5 -1.9 -1.1 -1.8 -1.4 -1.3 -1.7 -1.4 -2.2 0.5 -1.6 -1.5 -1.7 -1.3 -1.2 -1.6 -1.3 -0.3 -1.3 -2.3 -1.2 -1.7 -0.1 -1.2 -1.6 -1.5 -1.1 -1.9 -1.3 -1.7 -1.5 -0.6 -1.2 -1.6 -1.7 -1.4 -1.2